Alan K. Meeker, Ph.D. - Publications

Affiliations: 
2001 Johns Hopkins University, Baltimore, MD 
Area:
Molecular Biology, Cell Biology

111 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Marrone MT, Joshu CE, Peskoe SB, De Marzo AM, Heaphy CM, Lupold SE, Meeker AK, Platz EA. Adding the Team into T1 Translational Research: A Case Study of Multidisciplinary Team Science in the Evaluation of Biomarkers of Prostate Cancer Risk and Prognosis. Clinical Chemistry. PMID 30518666 DOI: 10.1373/clinchem.2018.293365  0.48
2018 Brosnan-Cashman JA, Yuan M, Graham MK, Rizzo AJ, Myers KM, Davis C, Zhang R, Esopi DM, Raabe EH, Eberhart CG, Heaphy CM, Meeker AK. ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner. Plos One. 13: e0204159. PMID 30226859 DOI: 10.1371/journal.pone.0204159  0.32
2018 Trabzonlu L, Kulac I, Zheng Q, Hicks JL, Haffner MC, Nelson WG, Sfanos KS, Ertunc O, Lotan TL, Heaphy CM, Meeker AK, Yegnasubramanian S, De Marzo AM. Molecular Pathology of High-Grade Prostatic Intraepithelial Neoplasia: Challenges and Opportunities. Cold Spring Harbor Perspectives in Medicine. PMID 30082453 DOI: 10.1101/cshperspect.a030403  0.48
2018 Weber KA, Heaphy CM, Joshu CE, Lu J, Rohrmann S, Bienstock JL, Agurs-Collins T, Meeker AK, Platz EA. Racial differences in maternal and umbilical cord blood leukocyte telomere length and their correlations. Cancer Causes & Control : Ccc. PMID 29980985 DOI: 10.1007/s10552-018-1054-8  0.32
2018 Tran PT, Meeker AK, Platz EA. Association between statin drug use and peripheral blood leukocyte telomere length in the National Health and Nutrition Examination Survey 1999-2002: a cross-sectional study. Annals of Epidemiology. PMID 29853162 DOI: 10.1016/j.annepidem.2018.04.010  0.32
2018 Bell WR, Meeker AK, Rizzo A, Rajpara S, Rosenthal IM, Flores Bellver M, Aparicio Domingo S, Zhong X, Barber JR, Joshu CE, Canto-Soler MV, Eberhart CG, Heaphy CM. A UNIQUE TELOMERE DNA EXPANSION PHENOTYPE IN HUMAN RETINAL ROD PHOTORECEPTORS ASSOCIATED WITH AGING AND DISEASE. Brain Pathology (Zurich, Switzerland). PMID 29668072 DOI: 10.1111/bpa.12618  0.32
2018 Haffner MC, Guner G, Taheri D, Netto GJ, Palsgrove DN, Zheng Q, Guedes LB, Kim K, Tsai H, Esopi DM, Lotan T, Sharma R, Meeker AK, Chinnaiyan AM, Nelson WG, et al. Comprehensive evaluation of PD-L1 expression in primary and metastatic prostate cancer. The American Journal of Pathology. PMID 29577933 DOI: 10.1016/j.ajpath.2018.02.014  0.48
2017 Joshu CE, Peskoe SB, Heaphy CM, Kenfield SA, Mucci LA, Giovannucci EL, Stampfer MJ, Yoon G, Lee TK, Hicks JL, De Marzo AM, Meeker AK, Platz EA. Current or recent smoking is associated with more variable telomere length in prostate stromal cells and prostate cancer cells. The Prostate. PMID 29164645 DOI: 10.1002/pros.23462  0.48
2017 Baena-Del Valle JA, Zheng Q, Esopi DM, Rubenstein M, Hubbard GK, Moncaliano MC, Hruszkewycz A, Vaghasia A, Yegnasubramanian S, Wheelan SJ, Meeker AK, Heaphy CM, Graham MK, De Marzo AM. MYC drives overexpression of telomerase RNA (hTR/TERC) in prostate cancer. The Journal of Pathology. PMID 28888037 DOI: 10.1002/path.4980  0.48
2017 Brennen WN, Zhang B, Kulac I, Kisteman LN, Antony L, Wang H, Meeker AK, De Marzo AM, Garraway IP, Denmeade SR, Isaacs JT. Mesenchymal stem cell infiltration during neoplastic transformation of the human prostate. Oncotarget. PMID 28493842 DOI: 10.18632/oncotarget.17362  0.48
2017 Peskoe SB, Barber JR, Zheng Q, Meeker AK, De Marzo AM, Platz EA, Lupold SE. Differential long-term stability of microRNAs and RNU6B snRNA in 12-20 year old archived formalin-fixed paraffin-embedded specimens. Bmc Cancer. 17: 32. PMID 28061773 DOI: 10.1186/s12885-016-3008-4  0.48
2016 Weber KA, Heaphy CM, Rohrmann S, Gonzalez B, Bienstock JL, Agurs-Collins T, Platz EA, Meeker AK. Influence of In Utero Maternal and Neonate Factors on Cord Blood Leukocyte Telomere Length: Clues to the Racial Disparity in Prostate Cancer? Prostate Cancer. 2016: 3691650. PMID 28070423 DOI: 10.1155/2016/3691650  0.32
2016 Holdhoff M, Guner G, Rodriguez FJ, Hicks JL, Zheng Q, Forman MS, Ye X, Grossman SA, Meeker AK, Heaphy CM, Eberhart CG, De Marzo AM, Arav-Boger R. Absence of cytomegalovirus in glioblastoma and other high-grade gliomas by real-time PCR, immunohistochemistry and in situ hybridization. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28034905 DOI: 10.1158/1078-0432.CCR-16-1490  0.48
2016 Kim JY, Brosnan-Cashman JA, An S, Kim SJ, Song KB, Kim MS, Kim MJ, Hwang DW, Meeker AK, Yu E, Kim SC, Hruban RH, Heaphy CM, Hong SM. Alternative lengthening of telomeres in primary pancreatic neuroendocrine neoplasms is associated with aggressive clinical behavior and poor survival. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27663587 DOI: 10.1158/1078-0432.CCR-16-1147  0.32
2016 Mukherjee A, Kumar B, Hatano K, Russell LM, Trock BJ, Searson PC, Meeker AK, Pomper MG, Lupold SE. Development and application of a novel model system to study 'active' and 'passive' tumor targeting. Molecular Cancer Therapeutics. PMID 27486224 DOI: 10.1158/1535-7163.MCT-16-0051  0.88
2016 Hackeng WM, Brosens LA, Poruk KE, Noë M, Hosoda W, Poling JS, Rizzo A, Campbell-Thompson M, Atkinson MA, Konukiewitz B, Klöppel G, Heaphy CM, Meeker AK, Wood LD. Aberrant Menin expression is an early event in pancreatic neuroendocrine tumorigenesis. Human Pathology. PMID 27342911 DOI: 10.1016/j.humpath.2016.06.006  0.88
2016 Shekhani MT, Barber JR, Bezerra SM, Heaphy CM, Roibon ND, Taheri D, Reis LO, Guner G, Joshu CE, Netto GJ, Meeker AK. Hi-res telomere FISH reveals intriguing anomalies in germ cell tumors. Human Pathology. PMID 27085557 DOI: 10.1016/j.humpath.2016.03.015  0.32
2016 Suryo Rahmanto Y, Jung JG, Wu RC, Kobayashi Y, Heaphy CM, Meeker AK, Wang TL, Shih IM. Inactivating ARID1A Tumor Suppressor Enhances TERT Transcription and Maintains Telomere Length in Cancer Cells. The Journal of Biological Chemistry. PMID 26953344 DOI: 10.1074/jbc.M115.707612  0.32
2015 Bodelon C, Heaphy CM, Meeker AK, Geller B, Vacek PM, Weaver DL, Chicoine RE, Shepherd JA, Mahmoudzadeh AP, Patel DA, Brinton LA, Sherman ME, Gierach GL. Leukocyte telomere length and its association with mammographic density and proliferative diagnosis among women undergoing diagnostic image-guided breast biopsy. Bmc Cancer. 15: 823. PMID 26519084 DOI: 10.1186/s12885-015-1860-2  0.88
2015 Cochran RL, Cidado J, Kim M, Zabransky DJ, Croessmann S, Chu D, Wong HY, Beaver JA, Cravero K, Erlanger B, Parsons H, Heaphy CM, Meeker AK, Lauring J, Park BH. Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes. Oncotarget. PMID 26246475  0.32
2015 Heaphy CM, Asch-Kendrick R, Argani P, Meeker AK, Cimino-Mathews A. Telomere length alterations unique to invasive lobular carcinoma. Human Pathology. 46: 1197-203. PMID 26092192 DOI: 10.1016/j.humpath.2015.05.001  0.88
2015 Joshu CE, Peskoe SB, Heaphy CM, Kenfield SA, Van Blarigan EL, Mucci LA, Giovannucci EL, Stampfer MJ, Yoon G, Lee TK, Hicks JL, De Marzo AM, Meeker AK, Platz EA. Prediagnostic Obesity and Physical Inactivity Are Associated with Shorter Telomere Length in Prostate Stromal Cells. Cancer Prevention Research (Philadelphia, Pa.). 8: 737-42. PMID 25990087 DOI: 10.1158/1940-6207.CAPR-15-0097  0.88
2015 Taube JM, Young GD, McMiller TL, Chen S, Salas JT, Pritchard TS, Xu H, Meeker AK, Fan J, Cheadle C, Berger AE, Pardoll DM, Topalian SL. Differential expression of immune-regulatory genes associated with PD-L1 display in melanoma: implications for PD-1 pathway blockade. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 25944800 DOI: 10.1158/1078-0432.CCR-15-0244  0.88
2015 Heaphy CM, Gaonkar G, Peskoe SB, Joshu CE, De Marzo AM, Lucia MS, Goodman PJ, Lippman SM, Thompson IM, Platz EA, Meeker AK. Prostate stromal cell telomere shortening is associated with risk of prostate cancer in the placebo arm of the Prostate Cancer Prevention Trial. The Prostate. 75: 1160-6. PMID 25893825 DOI: 10.1002/pros.22997  0.88
2015 Ferguson LR, Chen H, Collins AR, Connell M, Damia G, Dasgupta S, Malhotra M, Meeker AK, Amedei A, Amin A, Ashraf SS, Aquilano K, Azmi AS, Bhakta D, Bilsland A, et al. Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition. Seminars in Cancer Biology. PMID 25869442 DOI: 10.1016/j.semcancer.2015.03.005  0.88
2015 Julin B, Shui I, Heaphy CM, Joshu CE, Meeker AK, Giovannucci E, De Vivo I, Platz EA. Circulating leukocyte telomere length and risk of overall and aggressive prostate cancer British Journal of Cancer. 112: 769-776. PMID 25562437 DOI: 10.1038/bjc.2014.640  0.88
2015 Borodovsky A, Meeker AK, Kirkness EF, Zhao Q, Eberhart CG, Gallia GL, Riggins GJ. A model of a patient-derived IDH1 mutant anaplastic astrocytoma with alternative lengthening of telomeres. Journal of Neuro-Oncology. 121: 479-87. PMID 25471051 DOI: 10.1007/s11060-014-1672-2  0.88
2015 Cochran RL, Cidado J, Kim M, Zabransky DJ, Croessmann S, Chu D, Wong HY, Beaver JA, Cravero K, Erlanger B, Parsons H, Heaphy CM, Meeker AK, Lauring J, Park BH. Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes Oncotarget. 6: 25240-25251. DOI: 10.18632/oncotarget.4595  0.88
2015 Martin AM, Nirschl TR, Nirschl CJ, Francica BJ, Kochel CM, van Bokhoven A, Meeker AK, Lucia MS, Anders RA, DeMarzo AM, Drake CG. Paucity of PD-L1 expression in prostate cancer: innate and adaptive immune resistance Prostate Cancer and Prostatic Diseases. DOI: 10.1038/pcan.2015.39  0.88
2014 Zheng Q, Peskoe SB, Ribas J, Rafiqi F, Kudrolli T, Meeker AK, De Marzo AM, Platz EA, Lupold SE. Investigation of miR-21, miR-141, and miR-221 expression levels in prostate adenocarcinoma for associated risk of recurrence after radical prostatectomy. The Prostate. 74: 1655-62. PMID 25252191 DOI: 10.1002/pros.22883  0.88
2014 Bhavsar NA, Bream JH, Meeker AK, Drake CG, Peskoe SB, Dabitao D, De Marzo AM, Isaacs WB, Platz EA. A peripheral circulating TH1 cytokine profile is inversely associated with prostate cancer risk in CLUE II. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 23: 2561-7. PMID 25150281 DOI: 10.1158/1055-9965.EPI-14-0010  0.88
2014 Zhang Y, Calado R, Rao M, Hong JA, Meeker AK, Dumitriu B, Atay S, McCormick PJ, Garfield SH, Wangsa D, Padilla-Nash HM, Burkett S, Zhang M, Kunst TF, Peterson NR, et al. Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas. Plos One. 9: e101010. PMID 24983628 DOI: 10.1371/journal.pone.0101010  0.88
2014 Hurwitz LM, Heaphy CM, Joshu CE, Isaacs WB, Konishi Y, De Marzo AM, Isaacs SD, Wiley KE, Platz EA, Meeker AK. Telomere length as a risk factor for hereditary prostate cancer. The Prostate. 74: 359-64. PMID 24285042 DOI: 10.1002/pros.22755  0.88
2013 Haffner MC, Mosbruger T, Esopi DM, Fedor H, Heaphy CM, Walker DA, Adejola N, Gürel M, Hicks J, Meeker AK, Halushka MK, Simons JW, Isaacs WB, De Marzo AM, Nelson WG, et al. Tracking the clonal origin of lethal prostate cancer. The Journal of Clinical Investigation. 123: 4918-22. PMID 24135135 DOI: 10.1172/JCI70354  0.88
2013 Heaphy CM, Schreck KC, Raabe E, Mao XG, An P, Chu Q, Poh W, Jiao Y, Rodriguez FJ, Odia Y, Meeker AK, Eberhart CG. A glioblastoma neurosphere line with alternative lengthening of telomeres. Acta Neuropathologica. 126: 607-8. PMID 24022427 DOI: 10.1007/s00401-013-1174-x  0.88
2013 Mourkioti F, Kustan J, Kraft P, Day JW, Zhao MM, Kost-Alimova M, Protopopov A, DePinho RA, Bernstein D, Meeker AK, Blau HM. Role of telomere dysfunction in cardiac failure in Duchenne muscular dystrophy. Nature Cell Biology. 15: 895-904. PMID 23831727 DOI: 10.1038/ncb2790  0.88
2013 Heaphy CM, Yoon GS, Peskoe SB, Joshu CE, Lee TK, Giovannucci E, Mucci LA, Kenfield SA, Stampfer MJ, Hicks JL, De Marzo AM, Platz EA, Meeker AK. Prostate cancer cell telomere length variability and stromal cell telomere length as prognostic markers for metastasis and death. Cancer Discovery. 3: 1130-41. PMID 23779129 DOI: 10.1158/2159-8290.CD-13-0135  0.88
2013 Wood LD, Heaphy CM, Daniel HD, Naini BV, Lassman CR, Arroyo MR, Kamel IR, Cosgrove DP, Boitnott JK, Meeker AK, Torbenson MS. Chromophobe hepatocellular carcinoma with abrupt anaplasia: a proposal for a new subtype of hepatocellular carcinoma with unique morphological and molecular features. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 26: 1586-93. PMID 23640129 DOI: 10.1038/modpathol.2013.68  0.88
2013 Killela PJ, Reitman ZJ, Jiao Y, Bettegowda C, Agrawal N, Diaz LA, Friedman AH, Friedman H, Gallia GL, Giovanella BC, Grollman AP, He TC, He Y, Hruban RH, Jallo GI, ... ... Meeker AK, et al. TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal. Proceedings of the National Academy of Sciences of the United States of America. 110: 6021-6. PMID 23530248 DOI: 10.1073/pnas.1303607110  0.88
2013 Matthaei M, Lackner EM, Meng H, Hicks JL, Meeker AK, Eberhart CG, Jun AS. Tissue microarray analysis of cyclin-dependent kinase inhibitors p21 and p16 in Fuchs dystrophy. Cornea. 32: 473-8. PMID 23132454 DOI: 10.1097/ICO.0b013e31826f324e  0.88
2013 Nguyen DN, Heaphy CM, de Wilde RF, Orr BA, Odia Y, Eberhart CG, Meeker AK, Rodriguez FJ. Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas. Brain Pathology (Zurich, Switzerland). 23: 237-43. PMID 22928601 DOI: 10.1111/j.1750-3639.2012.00630.x  0.88
2012 Matthaei M, Meng H, Meeker AK, Eberhart CG, Jun AS. Endothelial Cdkn1a (p21) overexpression and accelerated senescence in a mouse model of Fuchs endothelial corneal dystrophy. Investigative Ophthalmology & Visual Science. 53: 6718-27. PMID 22956607 DOI: 10.1167/iovs.12-9669  0.88
2012 Jiao Y, Killela PJ, Reitman ZJ, Rasheed AB, Heaphy CM, de Wilde RF, Rodriguez FJ, Rosemberg S, Oba-Shinjo SM, Nagahashi Marie SK, Bettegowda C, Agrawal N, Lipp E, Pirozzi C, Lopez G, ... ... Meeker AK, et al. Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas. Oncotarget. 3: 709-22. PMID 22869205  0.88
2012 Lovejoy CA, Li W, Reisenweber S, Thongthip S, Bruno J, de Lange T, De S, Petrini JH, Sung PA, Jasin M, Rosenbluh J, Zwang Y, Weir BA, Hatton C, Ivanova E, ... ... Meeker AK, et al. Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway. Plos Genetics. 8: e1002772. PMID 22829774 DOI: 10.1371/journal.pgen.1002772  0.88
2012 de Wilde RF, Heaphy CM, Maitra A, Meeker AK, Edil BH, Wolfgang CL, Ellison TA, Schulick RD, Molenaar IQ, Valk GD, Vriens MR, Borel Rinkes IH, Offerhaus GJ, Hruban RH, Matsukuma KE. Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 25: 1033-9. PMID 22575867 DOI: 10.1038/modpathol.2012.53  0.88
2012 Zhou X, Meeker AK, Makambi KH, Kosti O, Kallakury BV, Sidawy MK, Loffredo CA, Zheng YL. Telomere length variation in normal epithelial cells adjacent to tumor: potential biomarker for breast cancer local recurrence. Carcinogenesis. 33: 113-8. PMID 22072619 DOI: 10.1093/carcin/bgr248  0.88
2011 Konishi H, Mohseni M, Tamaki A, Garay JP, Croessmann S, Karnan S, Ota A, Wong HY, Konishi Y, Karakas B, Tahir K, Abukhdeir AM, Gustin JP, Cidado J, Wang GM, ... ... Meeker AK, et al. Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 17773-8. PMID 21987798 DOI: 10.1073/pnas.1110969108  0.88
2011 Haffner MC, Chaux A, Meeker AK, Esopi DM, Gerber J, Pellakuru LG, Toubaji A, Argani P, Iacobuzio-Donahue C, Nelson WG, Netto GJ, De Marzo AM, Yegnasubramanian S. Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers. Oncotarget. 2: 627-37. PMID 21896958 DOI: 10.18632/oncotarget.316  0.88
2011 Heaphy CM, Subhawong AP, Hong SM, Goggins MG, Montgomery EA, Gabrielson E, Netto GJ, Epstein JI, Lotan TL, Westra WH, Shih IeM, Iacobuzio-Donahue CA, Maitra A, Li QK, Eberhart CG, ... ... Meeker AK, et al. Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes. The American Journal of Pathology. 179: 1608-15. PMID 21888887 DOI: 10.1016/j.ajpath.2011.06.018  0.88
2011 Wang Y, Meeker AK, Kowalski J, Tsai HL, Somervell H, Heaphy C, Sangenario LE, Prasad N, Westra WH, Zeiger MA, Umbricht CB. Telomere length is related to alternative splice patterns of telomerase in thyroid tumors. The American Journal of Pathology. 179: 1415-24. PMID 21763260 DOI: 10.1016/j.ajpath.2011.05.056  0.88
2011 Toubaji A, Albadine R, Meeker AK, Isaacs WB, Lotan T, Haffner MC, Chaux A, Epstein JI, Han M, Walsh PC, Partin AW, De Marzo AM, Platz EA, Netto GJ. Increased gene copy number of ERG on chromosome 21 but not TMPRSS2-ERG fusion predicts outcome in prostatic adenocarcinomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 24: 1511-20. PMID 21743434 DOI: 10.1038/modpathol.2011.111  0.88
2011 Heaphy CM, de Wilde RF, Jiao Y, Klein AP, Edil BH, Shi C, Bettegowda C, Rodriguez FJ, Eberhart CG, Hebbar S, Offerhaus GJ, McLendon R, Rasheed BA, He Y, Yan H, ... ... Meeker AK, et al. Altered telomeres in tumors with ATRX and DAXX mutations. Science (New York, N.Y.). 333: 425. PMID 21719641 DOI: 10.1126/science.1207313  0.88
2011 Toivanen R, Berman DM, Wang H, Pedersen J, Frydenberg M, Meeker AK, Ellem SJ, Risbridger GP, Taylor RA. Brief report: a bioassay to identify primary human prostate cancer repopulating cells. Stem Cells (Dayton, Ohio). 29: 1310-4. PMID 21674698 DOI: 10.1002/stem.668  0.88
2011 Kuhn E, Meeker AK, Visvanathan K, Gross AL, Wang TL, Kurman RJ, Shih IeM. Telomere length in different histologic types of ovarian carcinoma with emphasis on clear cell carcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 24: 1139-45. PMID 21499239 DOI: 10.1038/modpathol.2011.67  0.88
2011 Ryu B, Moriarty WF, Stine MJ, DeLuca A, Kim DS, Meeker AK, Grills LD, Switzer RA, Eller MS, Alani RM. Global analysis of BRAFV600E target genes in human melanocytes identifies matrix metalloproteinase-1 as a critical mediator of melanoma growth. The Journal of Investigative Dermatology. 131: 1579-83. PMID 21451543 DOI: 10.1038/jid.2011.65  0.88
2011 Haffner MC, De Marzo AM, Meeker AK, Nelson WG, Yegnasubramanian S. Transcription-induced DNA double strand breaks: both oncogenic force and potential therapeutic target? Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3858-64. PMID 21385925 DOI: 10.1158/1078-0432.CCR-10-2044  0.88
2011 Heaphy CM, Meeker AK. The potential utility of telomere-related markers for cancer diagnosis. Journal of Cellular and Molecular Medicine. 15: 1227-38. PMID 21352473 DOI: 10.1111/j.1582-4934.2011.01284.x  0.88
2011 Lotan TL, Gupta NS, Wang W, Toubaji A, Haffner MC, Chaux A, Hicks JL, Meeker AK, Bieberich CJ, De Marzo AM, Epstein JI, Netto GJ. ERG gene rearrangements are common in prostatic small cell carcinomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 24: 820-8. PMID 21336263 DOI: 10.1038/modpathol.2011.7  0.88
2011 Heaphy CM, Subhawong AP, Gross AL, Konishi Y, Kouprina N, Argani P, Visvanathan K, Meeker AK. Shorter telomeres in luminal B, HER-2 and triple-negative breast cancer subtypes. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 24: 194-200. PMID 21057458 DOI: 10.1038/modpathol.2010.198  0.88
2011 Hong SM, Heaphy CM, Shi C, Eo SH, Cho H, Meeker AK, Eshleman JR, Hruban RH, Goggins M. Telomeres are shortened in acinar-to-ductal metaplasia lesions associated with pancreatic intraepithelial neoplasia but not in isolated acinar-to-ductal metaplasias Modern Pathology. 24: 256-266. PMID 20871595 DOI: 10.1038/modpathol.2010.181  0.88
2010 Hector A, Montgomery EA, Karikari C, Canto M, Dunbar KB, Wang JS, Feldmann G, Hong SM, Haffner MC, Meeker AK, Holland SJ, Yu J, Heckrodt TJ, Zhang J, Ding P, et al. The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma. Cancer Biology & Therapy. 10: 1009-18. PMID 20818175 DOI: 10.4161/cbt.10.10.13248  0.88
2010 Perl S, Kushner JA, Buchholz BA, Meeker AK, Stein GM, Hsieh M, Kirby M, Pechhold S, Liu EH, Harlan DM, Tisdale JF. Significant human beta-cell turnover is limited to the first three decades of life as determined by in vivo thymidine analog incorporation and radiocarbon dating. The Journal of Clinical Endocrinology and Metabolism. 95: E234-9. PMID 20660050 DOI: 10.1210/jc.2010-0932  0.88
2010 Haffner MC, Aryee MJ, Toubaji A, Esopi DM, Albadine R, Gurel B, Isaacs WB, Bova GS, Liu W, Xu J, Meeker AK, Netto G, De Marzo AM, Nelson WG, Yegnasubramanian S. Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements. Nature Genetics. 42: 668-75. PMID 20601956 DOI: 10.1038/ng.613  0.88
2009 Albadine R, Latour M, Toubaji A, Haffner M, Isaacs WB, A Platz E, Meeker AK, Demarzo AM, Epstein JI, Netto GJ. TMPRSS2-ERG gene fusion status in minute (minimal) prostatic adenocarcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 22: 1415-22. PMID 19734849 DOI: 10.1038/modpathol.2009.121  0.88
2009 Subhawong AP, Heaphy CM, Argani P, Konishi Y, Kouprina N, Nassar H, Vang R, Meeker AK. The alternative lengthening of telomeres phenotype in breast carcinoma is associated with HER-2 overexpression. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 22: 1423-31. PMID 19734843 DOI: 10.1038/modpathol.2009.125  0.88
2009 Sfanos KS, Bruno TC, Meeker AK, De Marzo AM, Isaacs WB, Drake CG. Human prostate-infiltrating CD8+ T lymphocytes are oligoclonal and PD-1+. The Prostate. 69: 1694-703. PMID 19670224 DOI: 10.1002/pros.21020  0.88
2009 Koorstra JB, Hong SM, Shi C, Meeker AK, Ryu JK, Offerhaus GJ, Goggins MG, Hruban RH, Maitra A. Widespread activation of the DNA damage response in human pancreatic intraepithelial neoplasia. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 22: 1439-45. PMID 19668150 DOI: 10.1038/modpathol.2009.114  0.88
2009 Vander Griend DJ, Konishi Y, De Marzo AM, Isaacs JT, Meeker AK. Dual-label centromere and telomere FISH identifies human, rat, and mouse cell contribution to Multispecies recombinant urogenital sinus xenografts. The Prostate. 69: 1557-64. PMID 19562732 DOI: 10.1002/pros.21001  0.88
2009 Fujita K, Pavlovich CP, Netto GJ, Konishi Y, Isaacs WB, Ali S, De Marzo A, Meeker AK. Specific detection of prostate cancer cells in urine by multiplex immunofluorescence cytology. Human Pathology. 40: 924-33. PMID 19368959 DOI: 10.1016/j.humpath.2009.01.004  0.88
2009 Lotan TL, Toubaji A, Albadine R, Latour M, Herawi M, Meeker AK, DeMarzo AM, Platz EA, Epstein JI, Netto GJ. TMPRSS2-ERG gene fusions are infrequent in prostatic ductal adenocarcinomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 22: 359-65. PMID 19151660 DOI: 10.1038/modpathol.2008.236  0.88
2008 Wang Y, Kowalski J, Tsai HL, Marik R, Prasad N, Somervell H, Lo PK, Sangenario LE, Dyrskjot L, Orntoft TF, Westra WH, Meeker AK, Eshleman JR, Umbricht CB, Zeiger MA. Differentiating alternative splice variant patterns of human telomerase reverse transcriptase in thyroid neoplasms. Thyroid : Official Journal of the American Thyroid Association. 18: 1055-63. PMID 18816183 DOI: 10.1089/thy.2008.0101  0.88
2008 Sfanos KS, Bruno TC, Maris CH, Xu L, Thoburn CJ, DeMarzo AM, Meeker AK, Isaacs WB, Drake CG. Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 3254-61. PMID 18519750 DOI: 10.1158/1078-0432.CCR-07-5164  0.88
2008 Cummings SD, Ryu B, Samuels MA, Yu X, Meeker AK, Healey MA, Alani RM. Id1 delays senescence of primary human melanocytes. Molecular Carcinogenesis. 47: 653-9. PMID 18240291 DOI: 10.1002/mc.20422  0.88
2008 Joshua AM, Evans A, Van der Kwast T, Zielenska M, Meeker AK, Chinnaiyan A, Squire JA. Prostatic preneoplasia and beyond. Biochimica Et Biophysica Acta. 1785: 156-81. PMID 18166163 DOI: 10.1016/j.bbcan.2007.12.001  0.88
2008 Bechan GI, Meeker AK, De Marzo AM, Racke F, Jaffe R, Sugar E, Arceci RJ. Telomere length shortening in Langerhans cell histiocytosis. British Journal of Haematology. 140: 420-8. PMID 18162125 DOI: 10.1111/j.1365-2141.2007.06904.x  0.88
2007 Stewénius Y, Jin Y, Øra I, de Kraker J, Bras J, Frigyesi A, Alumets J, Sandstedt B, Meeker AK, Gisselsson D. Defective chromosome segregation and telomere dysfunction in aggressive Wilms' tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 6593-602. PMID 18006759 DOI: 10.1158/1078-0432.CCR-07-1081  0.88
2007 Kawai T, Hiroi S, Nakanishi K, Meeker AK. Telomere length and telomerase expression in atypical adenomatous hyperplasia and small bronchioloalveolar carcinoma of the lung. American Journal of Clinical Pathology. 127: 254-62. PMID 17210516 DOI: 10.1309/91PY0RBD9W8Y5GNX  0.88
2006 Hansel DE, Meeker AK, Hicks J, De Marzo AM, Lillemoe KD, Schulick R, Hruban RH, Maitra A, Argani P. Telomere length variation in biliary tract metaplasia, dysplasia, and carcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 19: 772-9. PMID 16557277 DOI: 10.1038/modpathol.3800591  0.88
2006 Meeker AK. Telomeres and telomerase in prostatic intraepithelial neoplasia and prostate cancer biology. Urologic Oncology. 24: 122-30. PMID 16520276 DOI: 10.1016/j.urolonc.2005.11.002  0.88
2004 Meeker AK, Argani P. Telomere shortening occurs early during breast tumorigenesis: a cause of chromosome destabilization underlying malignant transformation? Journal of Mammary Gland Biology and Neoplasia. 9: 285-96. PMID 15557801 DOI: 10.1023/B:JOMG.0000048775.04140.92  0.88
2004 Zeiger MA, Meeker AK. Telomerase as drug and drug target for the treatment of thyroid cancer Current Drug Targets: Immune, Endocrine and Metabolic Disorders. 4: 253-256. PMID 15379727 DOI: 10.2174/1568008043339794  0.88
2004 Meeker AK, Hicks JL, Iacobuzio-Donahue CA, Montgomery EA, Westra WH, Chan TY, Ronnett BM, De Marzo AM. Telomere length abnormalities occur early in the initiation of epithelial carcinogenesis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 3317-26. PMID 15161685 DOI: 10.1158/1078-0432.CCR-0984-03  0.88
2004 Montgomery E, Argani P, Hicks JL, DeMarzo AM, Meeker AK. Telomere lengths of translocation-associated and nontranslocation-associated sarcomas differ dramatically. The American Journal of Pathology. 164: 1523-9. PMID 15111298 DOI: 10.1016/S0002-9440(10)63710-8  0.88
2004 Meeker AK, Hicks JL, Gabrielson E, Strauss WM, De Marzo AM, Argani P. Telomere shortening occurs in subsets of normal breast epithelium as well as in situ and invasive carcinoma. The American Journal of Pathology. 164: 925-35. PMID 14982846 DOI: 10.1016/S0002-9440(10)63180-X  0.88
2004 De Marzo AM, DeWeese TL, Platz EA, Meeker AK, Nakayama M, Epstein JI, Isaacs WB, Nelson WG. Pathological and molecular mechanisms of prostate carcinogenesis: implications for diagnosis, detection, prevention, and treatment. Journal of Cellular Biochemistry. 91: 459-77. PMID 14755677 DOI: 10.1002/jcb.10747  0.88
2004 Meeker AK, De Marzo AM. Recent advances in telomere biology: implications for human cancer. Current Opinion in Oncology. 16: 32-8. PMID 14685090 DOI: 10.1097/00001622-200401000-00007  0.88
2003 De Marzo AM, Meeker AK, Zha S, Luo J, Nakayama M, Platz EA, Isaacs WB, Nelson WG. Human prostate cancer precursors and pathobiology. Urology. 62: 55-62. PMID 14607218 DOI: 10.1016/j.urology.2003.09.053  0.88
2002 Meeker AK, Hicks JL, Platz EA, March GE, Bennett CJ, Delannoy MJ, De Marzo AM. Telomere shortening is an early somatic DNA alteration in human prostate tumorigenesis. Cancer Research. 62: 6405-9. PMID 12438224  0.88
2002 van Heek NT, Meeker AK, Kern SE, Yeo CJ, Lillemoe KD, Cameron JL, Offerhaus GJ, Hicks JL, Wilentz RE, Goggins MG, De Marzo AM, Hruban RH, Maitra A. Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia. The American Journal of Pathology. 161: 1541-7. PMID 12414502 DOI: 10.1016/S0002-9440(10)64432-X  0.88
2002 Meeker AK, Gage WR, Hicks JL, Simon I, Coffman JR, Platz EA, March GE, De Marzo AM. Telomere length assessment in human archival tissues: combined telomere fluorescence in situ hybridization and immunostaining. The American Journal of Pathology. 160: 1259-68. PMID 11943711 DOI: 10.1016/S0002-9440(10)62553-9  0.88
1998 De Marzo AM, Nelson WG, Meeker AK, Coffey DS. Stem cell features of benign and malignant prostate epithelial cells. The Journal of Urology. 160: 2381-92. PMID 9817389 DOI: 10.1016/S0022-5347(01)62196-7  0.88
1998 De Marzo AM, Meeker AK, Epstein JI, Coffey DS. Prostate stem cell compartments: expression of the cell cycle inhibitor p27Kip1 in normal, hyperplastic, and neoplastic cells. The American Journal of Pathology. 153: 911-9. PMID 9736039 DOI: 10.1016/S0002-9440(10)65632-5  0.88
1998 Meeker AK, Sack GH. A fusion protein between serum amyloid A and staphylococcal nuclease - Synthesis, purification, and structural studies Proteins: Structure, Function and Genetics. 30: 381-387. PMID 9533622 DOI: 10.1002/(SICI)1097-0134(19980301)30:4<381::AID-PROT5>3.0.CO;2-M  0.88
1997 Meeker AK, Coffey DS. Telomerase: a promising marker of biological immortality of germ, stem, and cancer cells. A review. Biochemistry. Biokhimii︠a︡. 62: 1323-31. PMID 9467857  0.88
1996 Meeker AK, Sommerfeld HJ, Coffey DS. Telomerase is activated in the prostate and seminal vesicles of the castrated rat. Endocrinology. 137: 5743-6. PMID 8940411 DOI: 10.1210/endo.137.12.8940411  0.88
1996 Meeker AK, Garcia-Moreno E. B, Shortle D. Contributions of the ionizable amino acids to the stability of staphylococcal nuclease Biochemistry. 35: 6443-6449. PMID 8639591 DOI: 10.1021/bi960171+  0.88
1996 Sommerfeld HJ, Meeker AK, Piatyszek MA, Bova GS, Shay JW, Coffey DS. Telomerase activity: a prevalent marker of malignant human prostate tissue. Cancer Research. 56: 218-22. PMID 8548767  0.88
1995 Green SM, Gittis AG, Meeker AK, Lattman EE. One-step evolution of a dimer from a monomeric protein. Nature Structural Biology. 2: 746-51. PMID 7552745 DOI: 10.1038/nsb0995-746  0.88
1995 Sommerfeld HJ, Meeker AK, Posadas EM, Coffey DS. Frontiers in prostate cancer: Telomeres and chaos Cancer. 75: 2027-2035.  0.88
1994 Stites WE, Meeker AK, Shortle D. Evidence for strained interactions between side-chains and the polypeptide backbone Journal of Molecular Biology. 235: 27-32. PMID 8289248 DOI: 10.1016/S0022-2836(05)80008-7  0.88
1992 Green SM, Meeker AK, Shortle D. Contributions of the polar, uncharged amino acids to the stability of staphylococcal nuclease: Evidence for mutational effects on the free energy of the denatured state Biochemistry. 31: 5717-5728. PMID 1610820  0.88
1991 Weber DJ, Meeker AK, Mildvan AS. Interactions of the acid and base catalysts on staphylococcal nuclease as studied in a double mutant. Biochemistry. 30: 6103-14. PMID 1676297  0.88
1990 Shortle D, Stites WE, Meeker AK. Contributions of the large hydrophobic amino acids to the stability of staphylococcal nuclease Biochemistry. 29: 8033-8041. PMID 2261461  0.88
1989 Shortle D, Meeker AK, Gerring SL. Effects of denaturants at low concentrations on the reversible denaturation of staphylococcal nuclease Archives of Biochemistry and Biophysics. 272: 103-113. PMID 2544138 DOI: 10.1016/0003-9861(89)90200-2  0.88
1989 Shortle D, Meeker AK. Residual structure in large fragments of staphylococcal nuclease: Effects of amino acid substitutions Biochemistry. 28: 936-944. PMID 2540825  0.88
1988 Loll PJ, Meeker AK, Shortle D, Pease M, Lattman EE. Crystallization and preliminary X-ray analysis of a quadruple mutant of staphylococcal nuclease Journal of Biological Chemistry. 263: 18190-18192. PMID 3192532  0.88
1988 Shortle D, Meeker AK, Freire E. Stability mutants of staphylococcal nuclease: Large compensating enthalpy-entropy changes for the reversible denaturation reaction Biochemistry. 27: 4761-4768. PMID 3167015  0.88
1987 Talmadge JE, Talmadge CB, Zbar B, McEwen R, Meeker AK, Tribble H. In vivo immunologic selection of class I major histocompatibility complex gene deletion variants from the B16-BL6 melanoma. Journal of the National Cancer Institute. 78: 1215-21. PMID 3473258  0.88
1986 Hartmann D, Adams JS, Meeker AK, Schneider MA, Lenz BF, Talmadge JE. Dissociation of Therapeutic and Toxic Effects of Polyinosinic-Polycytidylic Acid Admixed with Poly-L-lysine and Solubilized with Carboxymethyl Cellulose in Tumor-bearing Mice Cancer Research. 46: 1331-1338. PMID 3484679  0.88
1986 Shortle D, Meeker AK. Mutant forms of staphylococcal nuclease with altered patterns of guanidine hydrochloride and urea denaturation Proteins: Structure, Function and Genetics. 1: 81-89. PMID 3449854  0.88
1984 Talmadge JE, Schneider ME, Meeker AK, Adams J. Stimulation of murine lymphocytes (NK cells and T cells) by human recombinant interleukin-2 (IL-2) Federation Proceedings. 43.  0.88
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