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Dai Stephens - Publications

Affiliations: 
University of Sussex, Falmer, England, United Kingdom 
Area:
behavioral neuroscience, alcohol and drug abuse
Website:
http://www.lifesci.susx.ac.uk/home/Dai_Stephens/

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Macpherson T, Dixon CI, Robertson J, Sindarto MM, Janak PH, Belelli D, Lambert JJ, Stephens DN, King SL. α4-containing GABA receptors on DRD2-neurons of the nucleus accumbens mediate instrumental responding for conditioned reinforcers, and its potentiation by cocaine. Eneuro. PMID 37553242 DOI: 10.1523/ENEURO.0236-23.2023  0.825
2019 Dixon CI, Walker SE, Swinny J, Belelli D, Lambert JJ, King SL, Stephens DN. Early-life stress influences acute and sensitized responses of adult mice to cocaine by interacting with GABAA α2 receptor expression. Behavioural Pharmacology. PMID 30724801 DOI: 10.1097/Fbp.0000000000000466  0.815
2018 Mitchell SJ, Maguire EP, Cunningham L, Gunn BG, Linke M, Zechner U, Dixon CI, King SL, Stephens DN, Swinny JD, Belelli D, Lambert JJ. Early-life adversity selectively impairs α2-GABA receptor expression in the mouse nucleus accumbens and influences the behavioral effects of cocaine. Neuropharmacology. PMID 30138693 DOI: 10.1016/J.Neuropharm.2018.08.021  0.811
2017 Duka T, Nikolaou K, King SL, Banaschewski T, Bokde AL, Büchel C, Carvalho FM, Conrod PJ, Flor H, Gallinat J, Garavan H, Heinz A, Jia T, Gowland P, Martinot JL, ... ... Stephens DN, et al. GABRB1 Single Nucleotide Polymorphism Associated with Altered Brain Responses (but not Performance) during Measures of Impulsivity and Reward Sensitivity in Human Adolescents. Frontiers in Behavioral Neuroscience. 11: 24. PMID 28261068 DOI: 10.3389/Fnbeh.2017.00024  0.503
2016 Stephens DN, King SL, Lambert JJ, Belelli D, Duka T. GABAA Receptor Subtype Involvement in Addictive Behaviour. Genes, Brain, and Behavior. PMID 27539865 DOI: 10.1111/Gbb.12321  0.54
2015 Duka T, Dixon CI, Trick L, Crombag HS, King SL, Stephens DN. Motivational Effects of Methylphenidate are Associated with GABRA2 Variants Conferring Addiction Risk. Frontiers in Behavioral Neuroscience. 9: 304. PMID 26635556 DOI: 10.3389/Fnbeh.2015.00304  0.793
2014 Dixon CI, Halbout B, King SL, Stephens DN. Deletion of the GABAA α2-subunit does not alter self administration of cocaine or reinstatement of cocaine seeking. Psychopharmacology. 231: 2695-703. PMID 24481569 DOI: 10.1007/S00213-014-3443-3  0.81
2014 Maguire EP, Macpherson T, Swinny JD, Dixon CI, Herd MB, Belelli D, Stephens DN, King SL, Lambert JJ. Tonic inhibition of accumbal spiny neurons by extrasynaptic α4βδ GABAA receptors modulates the actions of psychostimulants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 823-38. PMID 24431441 DOI: 10.1523/Jneurosci.3232-13.2014  0.809
2014 Weir RK, Dudley JA, Yan TC, Grabowska EM, Peña-Oliver Y, Ripley TL, Stephens DN, Stanford SC, Hunt SP. The influence of test experience and NK1 receptor antagonists on the performance of NK1R-/- and wild type mice in the 5-Choice Serial Reaction-Time Task. Journal of Psychopharmacology (Oxford, England). 28: 270-81. PMID 23845920 DOI: 10.1177/0269881113495722  0.32
2013 Anstee QM, Knapp S, Maguire EP, Hosie AM, Thomas P, Mortensen M, Bhome R, Martinez A, Walker SE, Dixon CI, Ruparelia K, Montagnese S, Kuo YT, Herlihy A, Bell JD, ... ... Stephens DN, et al. Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition. Nature Communications. 4: 2816. PMID 24281383 DOI: 10.1038/Ncomms3816  0.712
2013 Stephens DN, Crombag HS, Duka T. The challenge of studying parallel behaviors in humans and animal models. Current Topics in Behavioral Neurosciences. 13: 611-45. PMID 21671191 DOI: 10.1007/7854_2011_133  0.616
2013 Macpherson T, Stephens D, King S. C.16 - Extrasynaptic Alpha4-Containing Gabaa Receptors Within The Nucleus Accumbens Produce Pathway-Specific Effects On Expression Of Cocaine-Induced Conditioned Place Preference Behavioural Pharmacology. 24. DOI: 10.1097/01.Fbp.0000434800.02419.2F  0.474
2013 Dixon C, Walker S, Lambert J, Belelli D, King S, Stephens D. C.15 - EARLY LIFE STRESS ALTERS RESPONSIVITY TO COCAINE Behavioural Pharmacology. 24: e34. DOI: 10.1097/01.Fbp.0000434799.94795.2E  0.752
2013 Lambert J, Maguire E, Cunningham L, Mitchell S, Gunn B, Walker S, Claire D, King S, Jerome SS, Stephens D, Belelli D. S.6.3 - STRESS EXPOSURE DURING EARLY DEVELOPMENT ALTERS ACCUMBENS GABAA RECEPTOR FUNCTION IN ADULTHOOD AND RESULTS IN SENSITIZED RESPONSES TO COCAINE Behavioural Pharmacology. 24: e7. DOI: 10.1097/01.Fbp.0000434706.84012.1B  0.306
2012 Dixon CI, Walker SE, King SL, Stephens DN. Deletion of the gabra2 gene results in hypersensitivity to the acute effects of ethanol but does not alter ethanol self administration. Plos One. 7: e47135. PMID 23115637 DOI: 10.1371/Journal.Pone.0047135  0.768
2012 Whelan R, Conrod PJ, Poline JB, Lourdusamy A, Banaschewski T, Barker GJ, Bellgrove MA, Büchel C, Byrne M, Cummins TD, Fauth-Bühler M, Flor H, Gallinat J, Heinz A, Ittermann B, ... ... Stephens DN, et al. Adolescent impulsivity phenotypes characterized by distinct brain networks. Nature Neuroscience. 15: 920-5. PMID 22544311 DOI: 10.1038/Nn.3092  0.388
2012 Peña-Oliver Y, Buchman VL, Dalley JW, Robbins TW, Schumann G, Ripley TL, King SL, Stephens DN. Deletion of alpha-synuclein decreases impulsivity in mice. Genes, Brain, and Behavior. 11: 137-46. PMID 22142176 DOI: 10.1111/j.1601-183X.2011.00758.x  0.521
2011 Duka T, Crombag HS, Stephens DN. Experimental medicine in drug addiction: towards behavioral, cognitive and neurobiological biomarkers. Journal of Psychopharmacology (Oxford, England). 25: 1235-55. PMID 21169391 DOI: 10.1177/0269881110388324  0.65
2011 Halbout B, Perreau-Lenz S, Dixon CI, Stephens DN, Spanagel R. Per1(Brdm1) mice self-administer cocaine and reinstate cocaine-seeking behaviour following extinction. Behavioural Pharmacology. 22: 76-80. PMID 21127416 DOI: 10.1097/Fbp.0B013E328341E9Ca  0.805
2010 Schumann G, Loth E, Banaschewski T, Barbot A, Barker G, Büchel C, Conrod PJ, Dalley JW, Flor H, Gallinat J, Garavan H, Heinz A, Itterman B, Lathrop M, Mallik C, ... ... Stephens DN, et al. The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology. Molecular Psychiatry. 15: 1128-39. PMID 21102431 DOI: 10.1038/Mp.2010.4  0.39
2010 O'Connor EC, Stephens DN, Crombag HS. Modeling appetitive Pavlovian-instrumental interactions in mice. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 8.25. PMID 20938924 DOI: 10.1002/0471142301.ns0825s53  0.676
2010 Novak M, Halbout B, O'Connor EC, Rodriguez Parkitna J, Su T, Chai M, Crombag HS, Bilbao A, Spanagel R, Stephens DN, Schütz G, Engblom D. Incentive learning underlying cocaine-seeking requires mGluR5 receptors located on dopamine D1 receptor-expressing neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 11973-82. PMID 20826661 DOI: 10.1523/Jneurosci.2550-10.2010  0.827
2010 O'Connor EC, Crombag HS, Mead AN, Stephens DN. The mGluR5 antagonist MTEP dissociates the acquisition of predictive and incentive motivational properties of reward-paired stimuli in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1807-17. PMID 20375996 DOI: 10.1038/Npp.2010.48  0.802
2010 Stephens DN, Duka T, Crombag HS, Cunningham CL, Heilig M, Crabbe JC. Reward sensitivity: issues of measurement, and achieving consilience between human and animal phenotypes. Addiction Biology. 15: 145-68. PMID 20148777 DOI: 10.1111/J.1369-1600.2009.00193.X  0.669
2010 Dixon CI, Morris HV, Breen G, Desrivieres S, Jugurnauth S, Steiner RC, Vallada H, Guindalini C, Laranjeira R, Messas G, Rosahl TW, Atack JR, Peden DR, Belelli D, Lambert JJ, ... ... Stephens DN, et al. Cocaine effects on mouse incentive-learning and human addiction are linked to alpha2 subunit-containing GABAA receptors. Proceedings of the National Academy of Sciences of the United States of America. 107: 2289-94. PMID 20133874 DOI: 10.1073/Pnas.0910117107  0.821
2009 Morris HV, Nilsson S, Dixon CI, Stephens DN, Clifton PG. Alpha1- and alpha2-containing GABAA receptor modulation is not necessary for benzodiazepine-induced hyperphagia. Appetite. 52: 675-83. PMID 19501766 DOI: 10.1016/J.Appet.2009.03.006  0.734
2009 George SA, Hutson PH, Stephens DN. Differential effects of MPEP and diazepam in tests of conditioned emotional response and Pavlovian-to-instrumental transfer suggests 'anxiolytic' effects are mediated by different mechanisms. Psychopharmacology. 204: 499-509. PMID 19205667 DOI: 10.1007/S00213-009-1479-6  0.593
2008 Morris HV, Dawson GR, Reynolds DS, Atack JR, Rosahl TW, Stephens DN. Alpha2-containing GABA(A) receptors are involved in mediating stimulant effects of cocaine. Pharmacology, Biochemistry, and Behavior. 90: 9-18. PMID 18358520 DOI: 10.1016/j.pbb.2008.02.010  0.348
2008 Dixon CI, Rosahl TW, Stephens DN. Targeted deletion of the GABRA2 gene encoding alpha2-subunits of GABA(A) receptors facilitates performance of a conditioned emotional response, and abolishes anxiolytic effects of benzodiazepines and barbiturates. Pharmacology, Biochemistry, and Behavior. 90: 1-8. PMID 18313124 DOI: 10.1016/J.Pbb.2008.01.015  0.778
2007 Mead AN, Zamanillo D, Becker N, Stephens DN. AMPA-receptor GluR1 subunits are involved in the control over behavior by cocaine-paired cues. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 343-53. PMID 16495937 DOI: 10.1038/Sj.Npp.1301045  0.824
2006 Mead AN, Morris HV, Dixon CI, Rulten SL, Mayne LV, Zamanillo D, Stephens DN. AMPA receptor GluR2, but not GluR1, subunit deletion impairs emotional response conditioning in mice. Behavioral Neuroscience. 120: 241-8. PMID 16719688 DOI: 10.1037/0735-7044.120.2.241  0.806
2006 Collinson N, Atack JR, Laughton P, Dawson GR, Stephens DN. An inverse agonist selective for alpha5 subunit-containing GABAA receptors improves encoding and recall but not consolidation in the Morris water maze. Psychopharmacology. 188: 619-28. PMID 16633803 DOI: 10.1007/s00213-006-0361-z  0.648
2005 Mead AN, Brown G, Le Merrer J, Stephens DN. Effects of deletion of gria1 or gria2 genes encoding glutamatergic AMPA-receptor subunits on place preference conditioning in mice. Psychopharmacology. 179: 164-71. PMID 15619119 DOI: 10.1007/S00213-004-2071-8  0.831
2005 Stephens D, Mead A. S6 EXPLORING THE ROLE OF AMPA RECEPTOR SUBUNITS IN ADDICTIVE PROCESSES USING MICE WITH TARGETED DELETIONS OF GLUR1 AND GLUR2 SUBUNITS Behavioural Pharmacology. 16: S2. DOI: 10.1097/00008877-200509001-00006  0.791
2004 Stephens DN, Mead AN. Behavioural plasticity-induced changes in drug response. Commentary on Badiani and Robinson drug-induced neurobehavioral plasticity: the role of environmental context. Behavioural Pharmacology. 15: 377-80. PMID 15343063 DOI: 10.1097/00008877-200409000-00011  0.751
2004 Horwood JM, Ripley TL, Stephens DN. Evidence for disrupted NMDA receptor function in tissue plasminogen activator knockout mice. Behavioural Brain Research. 150: 127-38. PMID 15033286 DOI: 10.1016/S0166-4328(03)00248-1  0.786
2003 Mead AN, Stephens DN. Involvement of AMPA receptor GluR2 subunits in stimulus-reward learning: evidence from glutamate receptor gria2 knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9500-7. PMID 14573529 DOI: 10.1523/Jneurosci.23-29-09500.2003  0.828
2003 Stephens DN, Mead AN. What role do GluR1 subunits play in drug abuse? Trends in Neurosciences. 26: 181-2; author reply . PMID 12689767 DOI: 10.1016/S0166-2236(03)00080-8  0.764
2003 Mead AN, Stephens DN. Selective disruption of stimulus-reward learning in glutamate receptor gria1 knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1041-8. PMID 12574434 DOI: 10.1523/Jneurosci.23-03-01041.2003  0.822
2002 Ripley TL, Gadd CA, De Felipe C, Hunt SP, Stephens DN. Lack of self-administration and behavioural sensitisation to morphine, but not cocaine, in mice lacking NK1 receptors. Neuropharmacology. 43: 1258-68. PMID 12527475 DOI: 10.1016/S0028-3908(02)00295-2  0.422
2002 Stephens DN, Mead AN, Ripley TL. Studying the neurobiology of stimulant and alcohol abuse and dependence in genetically manipulated mice. Behavioural Pharmacology. 13: 327-45. PMID 12394407 DOI: 10.1097/00008877-200209000-00004  0.765
2002 Brown G, Stephens DN. Effects of cocaine on responding for ethanol or sucrose under a progressive ratio schedule. Behavioural Pharmacology. 13: 157-62. PMID 11981228  0.327
2001 Horwood JM, Ripley TL, Stephens DN. DRL performance in mice with deletion of tPA, uPA or PAI-1 genes. Behavioural Pharmacology. 12: 487-96. PMID 11742143  0.776
2001 Ripley TL, Horwood JM, Stephens DN. Evidence for impairment of behavioural inhibition in performance of operant tasks in tPA-/- mice. Behavioural Brain Research. 125: 215-27. PMID 11682113 DOI: 10.1016/S0166-4328(01)00303-5  0.795
2000 Jackson A, Mead AN, Stephens DN. Behavioural effects of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate-receptor antagonists and their relevance to substance abuse. Pharmacology & Therapeutics. 88: 59-76. PMID 11033384 DOI: 10.1016/S0163-7258(00)00078-4  0.791
2000 Stephens DN, Elliman TD, Dunworth SJ. State-dependent behavioural sensitization: evidence from a chlordiazepoxide state. Behavioural Pharmacology. 11: 161-7. PMID 10877121  0.305
2000 Dunworth SJ, Mead AN, Stephens DN. Previous experience of withdrawal from chronic diazepam ameliorates the aversiveness of precipitated withdrawal and reduces withdrawal-induced c-fos expression in nucleus accumbens. The European Journal of Neuroscience. 12: 1501-8. PMID 10762378 DOI: 10.1046/J.1460-9568.2000.00036.X  0.782
1999 Mead AN, Vasilaki A, Spyraki C, Duka T, Stephens DN. AMPA-receptor involvement in c-fos expression in the medial prefrontal cortex and amygdala dissociates neural substrates of conditioned activity and conditioned reward. The European Journal of Neuroscience. 11: 4089-98. PMID 10583497 DOI: 10.1046/J.1460-9568.1999.00828.X  0.787
1999 Mead AN, Stephens DN. CNQX but not NBQX prevents expression of amphetamine-induced place preference conditioning: a role for the glycine site of the NMDA receptor, but not AMPA receptors. The Journal of Pharmacology and Experimental Therapeutics. 290: 9-15. PMID 10381753  0.786
1999 Ripley TL, Rocha BA, Oglesby MW, Stephens DN. Increased sensitivity to cocaine, and over-responding during cocaine self-administration in tPA knockout mice. Brain Research. 826: 117-27. PMID 10216203 DOI: 10.1016/S0006-8993(99)01280-9  0.407
1998 Mead AN, Stephens DN. AMPA-receptors are involved in the expression of amphetamine-induced behavioural sensitisation, but not in the expression of amphetamine-induced conditioned activity in mice. Neuropharmacology. 37: 1131-8. PMID 9833643 DOI: 10.1016/S0028-3908(98)00101-4  0.817
1998 Jackson A, Mead AN, Rocha BA, Stephens DN. AMPA receptors and motivation for drug: effect of the selective antagonist NBQX on behavioural sensitization and on self-administration in mice. Behavioural Pharmacology. 9: 457-67. PMID 9832931 DOI: 10.1097/00008877-199809000-00009  0.825
1998 Dunworth SJ, Stephens DN. Sensitisation to repeated withdrawal, in mice treated chronically with diazepam, is blocked by an NMDA receptor antagonist. Psychopharmacology. 136: 308-10. PMID 9566818 DOI: 10.1007/s002130050571  0.318
1998 Ripley TL, Stephens DN. EFFECT OF COCAINE ON DRL PERFORMANCE IN tPA-/- MICE Behavioural Pharmacology. 9: S77. DOI: 10.1097/00008877-199808000-00177  0.372
1998 Mead AN, Stephens DN. THE ROLE OF AMPA RECEPTORS IN CONDITIONED REINFORCEMENT Behavioural Pharmacology. 9: S61. DOI: 10.1097/00008877-199808000-00133  0.782
1989 Stephens DN, Weidmann R. Blockade of FG 7142 kindling by anticonvulsants acting at sites distant from the benzodiazepine receptor. Brain Research. 492: 89-98. PMID 2546658 DOI: 10.1016/0006-8993(89)90892-5  0.319
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