| Year |
Citation |
Score |
| 2021 |
Sletten AC, Davidson JW, Yagabasan B, Moores S, Schwaiger-Haber M, Fujiwara H, Gale S, Jiang X, Sidhu R, Gelman S, Zhao S, Patti G, Ory DS, Schaffer JE. Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis. Nature Communications. 12: 5214. PMID 34471131 DOI: 10.1038/s41467-021-25457-y |
0.441 |
|
| 2020 |
Schaffer JE. Death by lipids: the role of small nucleolar RNAs in metabolic stress. The Journal of Biological Chemistry. PMID 32393576 DOI: 10.1074/Jbc.Aw120.011105 |
0.54 |
|
| 2020 |
Peterson LR, Jiang X, Chen L, Goldberg AC, Farmer MS, Ory DS, Schaffer JE. Alterations in plasma triglycerides and ceramides: links with cardiac function in humans with type 2 diabetes. Journal of Lipid Research. PMID 32393551 DOI: 10.1194/Jlr.Ra120000669 |
0.353 |
|
| 2020 |
Feltes M, Gale SE, Moores S, Ory DS, Schaffer JE. Monitoring the itinerary of lysosomal cholesterol in Niemann-Pick Type C1-deficient cells after cyclodextrin treatment. Journal of Lipid Research. PMID 31988149 DOI: 10.1194/Jlr.Ra119000571 |
0.361 |
|
| 2020 |
Schaffer JE. Death by Lipids: role of noncoding RNAs in metabolic stress The Faseb Journal. 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.00168 |
0.396 |
|
| 2019 |
Sidhu R, Mondjinou Y, Qian M, Song H, Kumar AB, Hong X, Hsu FF, Dietzen DJ, Yanjanin NM, Porter FD, Berry-Kravis E, Vite CH, Gelb MH, Schaffer JE, Ory DS, et al. N-Acyl-O-phosphocholineserines: structures of a novel class of lipids that are biomarkers for Niemann-Pick C1 disease. Journal of Lipid Research. PMID 31201291 DOI: 10.1194/Jlr.Ra119000157 |
0.335 |
|
| 2019 |
Davidson J, Molitor E, Moores S, Gale SE, Subramanian K, Jiang X, Sidhu R, Kell P, Zhang J, Fujiwara H, Davidson C, Helquist P, Melancon BJ, Grigalunas M, Liu G, ... ... Schaffer JE, et al. 2-Hydroxypropyl-β-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. PMID 31051283 DOI: 10.1016/J.Bbalip.2019.04.011 |
0.309 |
|
| 2019 |
Feltes M, Moores S, Gale SE, Krishnan K, Mydock-McGrane L, Covey DF, Ory DS, Schaffer JE. Synthesis and characterization of diazirine alkyne probes for the study of intracellular cholesterol trafficking. Journal of Lipid Research. PMID 30617147 DOI: 10.1194/Jlr.D091470 |
0.377 |
|
| 2018 |
Goldberg IJ, Reue K, Abumrad NA, Bickel PE, Cohen S, Fisher EA, Galis ZS, Granneman JG, Lewandowski ED, Murphy R, Olive M, Schaffer JE, Schwartz-Longacre L, Shulman GI, Walther TC, et al. Deciphering the Role of Lipid Droplets in Cardiovascular Disease: A Report From the 2017 National Heart, Lung, and Blood Institute Workshop. Circulation. 138: 305-315. PMID 30012703 DOI: 10.1161/Circulationaha.118.033704 |
0.319 |
|
| 2018 |
Rimer JM, Lee J, Holley CL, Crowder RJ, Chen DL, Hanson PI, Ory DS, Schaffer JE. Long-Range Function of Secreted Small Nucleolar RNAs that Direct 2'-O-Methylation. The Journal of Biological Chemistry. PMID 29980600 DOI: 10.1074/Jbc.Ra118.003410 |
0.695 |
|
| 2018 |
Sletten AC, Peterson LR, Schaffer JE. Manifestations and mechanisms of myocardial lipotoxicity in obesity. Journal of Internal Medicine. PMID 29331057 DOI: 10.1111/Joim.12728 |
0.406 |
|
| 2017 |
Tsushima K, Bugger H, Wende AR, Soto J, Jenson GA, Tor AR, McGlauflin R, Kenny HC, Zhang Y, Souvenir R, Hu XX, Black CL, Pereira RO, Lira VA, Spitzer K, ... ... Schaffer JE, et al. Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induces Post-Translational Modifications of AKAP121, DRP1 and OPA1 That Promote Mitochondrial Fission. Circulation Research. PMID 29092894 DOI: 10.1161/Circresaha.117.311307 |
0.327 |
|
| 2017 |
Li MW, Sletten AC, Lee J, Pyles KD, Matkovich SJ, Ory DS, Schaffer JE. Nuclear export factor 3 regulates localization of small nucleolar RNAs. The Journal of Biological Chemistry. PMID 29021253 DOI: 10.1074/Jbc.M117.818146 |
0.409 |
|
| 2017 |
Jackson CE, Scruggs BS, Schaffer JE, Hanson PI. Effects of Inhibiting VPS4 Support a General Role for ESCRTs in Extracellular Vesicle Biogenesis. Biophysical Journal. PMID 28629620 DOI: 10.1016/J.Bpj.2017.05.032 |
0.754 |
|
| 2016 |
McCommis KS, Hodges WT, Brunt EM, Nalbantoglu I, McDonald WG, Holley C, Fujiwara H, Schaffer JE, Colca JR, Finck BN. Targeting the Mitochondrial Pyruvate Carrier Attenuates Fibrosis in a Mouse Model of Nonalcoholic Steatohepatitis. Hepatology (Baltimore, Md.). PMID 28027586 DOI: 10.1002/Hep.29025 |
0.679 |
|
| 2016 |
Lee J, Harris AN, Holley CL, Mahadevan J, Pyles KD, Lavagnino Z, Scherrer DE, Fujiwara H, Sidhu R, Zhang J, Huang SC, Piston DW, Remedi MS, Urano F, Ory DS, ... Schaffer JE, et al. Rpl13a small nucleolar RNAs regulate systemic glucose metabolism. The Journal of Clinical Investigation. PMID 27820699 DOI: 10.1172/Jci88069 |
0.723 |
|
| 2016 |
Caputa G, Schaffer JE. RNA Regulation of Lipotoxicity and Metabolic Stress. Diabetes. PMID 27288006 DOI: 10.2337/Db16-0147 |
0.418 |
|
| 2016 |
Schaffer JE. Lipotoxicity: The Many Roads to Cell Dysfunction and Cell Death: Introduction to a thematic review series. Journal of Lipid Research. PMID 27260998 DOI: 10.1194/Jlr.E069880 |
0.303 |
|
| 2016 |
Jiang X, Sidhu R, Mydock-McGrane L, Hsu FF, Covey DF, Scherrer DE, Earley B, Gale SE, Farhat NY, Porter FD, Dietzen DJ, Orsini JJ, Berry-Kravis E, Zhang X, Reunert J, ... ... Schaffer JE, et al. Development of a bile acid-based newborn screen for Niemann-Pick disease type C. Science Translational Medicine. 8: 337ra63. PMID 27147587 DOI: 10.1126/Scitranslmed.Aaf2326 |
0.307 |
|
| 2015 |
Airhart S, Cade WT, Jiang H, Coggan AR, Racette SB, Korenblat K, Spearie CA, Waller S, O'Connor R, Bashir A, Ory DS, Schaffer JE, Novak E, Farmer M, Waggoner AD, et al. A Diet Rich in Medium-chain Fatty Acids Improves Systolic Function and Alters the Lipidomic Profile in Patients with Type 2 Diabetes: a Pilot Study. The Journal of Clinical Endocrinology and Metabolism. jc20153292. PMID 26652763 DOI: 10.1210/Jc.2015-3292 |
0.371 |
|
| 2015 |
Iaea DB, Gale SE, Bielska AA, Krishnan K, Fujiwara H, Jiang H, Maxfield FR, Schlesinger PH, Covey DF, Schaffer JE, Ory DS. A novel intrinsically fluorescent probe for study of uptake and trafficking of 25-hydroxycholesterol. Journal of Lipid Research. PMID 26497473 DOI: 10.1194/Jlr.D064287 |
0.376 |
|
| 2015 |
Caputa G, Zhao S, Criado AE, Ory DS, Duncan JG, Schaffer JE. RNASET2 is required for ROS propagation during oxidative stress-mediated cell death. Cell Death and Differentiation. PMID 26206090 DOI: 10.1038/Cdd.2015.105 |
0.474 |
|
| 2015 |
Praggastis M, Tortelli B, Zhang J, Fujiwara H, Sidhu R, Chacko A, Chen Z, Chung C, Lieberman AP, Sikora J, Davidson C, Walkley SU, Pipalia NH, Maxfield FR, Schaffer JE, et al. A Murine Niemann-Pick C1 I1061T Knock-In Model Recapitulates the Pathological Features of the Most Prevalent Human Disease Allele. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8091-106. PMID 26019327 DOI: 10.1523/Jneurosci.4173-14.2015 |
0.34 |
|
| 2015 |
Jinn S, Brandis KA, Ren A, Chacko A, Dudley-Rucker N, Gale SE, Sidhu R, Fujiwara H, Jiang H, Olsen BN, Schaffer JE, Ory DS. snoRNA U17 regulates cellular cholesterol trafficking. Cell Metabolism. 21: 855-67. PMID 25980348 DOI: 10.1016/J.Cmet.2015.04.010 |
0.39 |
|
| 2015 |
Holley CL, Li MW, Scruggs BS, Matkovich SJ, Ory DS, Schaffer JE. Cytosolic accumulation of small nucleolar RNAs (snoRNAs) is dynamically regulated by NADPH oxidase. The Journal of Biological Chemistry. 290: 11741-8. PMID 25792744 DOI: 10.1074/Jbc.M115.637413 |
0.785 |
|
| 2015 |
Elezaby A, Sverdlov AL, Tu VH, Soni K, Luptak I, Qin F, Liesa M, Shirihai OS, Rimer J, Schaffer JE, Wilson S C, Edward J M. Mitochondrial remodeling in mice with cardiomyocyte-specific lipid overload. Journal of Molecular and Cellular Cardiology. 79: 275-83. PMID 25497302 DOI: 10.1016/J.Yjmcc.2014.12.001 |
0.434 |
|
| 2013 |
Brandis KA, Gale S, Jinn S, Langmade SJ, Dudley-Rucker N, Jiang H, Sidhu R, Ren A, Goldberg A, Schaffer JE, Ory DS. Box C/D small nucleolar RNA (snoRNA) U60 regulates intracellular cholesterol trafficking. The Journal of Biological Chemistry. 288: 35703-13. PMID 24174535 DOI: 10.1074/Jbc.M113.488577 |
0.434 |
|
| 2013 |
Fan M, Sidhu R, Fujiwara H, Tortelli B, Zhang J, Davidson C, Walkley SU, Bagel JH, Vite C, Yanjanin NM, Porter FD, Schaffer JE, Ory DS. Identification of Niemann-Pick C1 disease biomarkers through sphingolipid profiling. Journal of Lipid Research. 54: 2800-14. PMID 23881911 DOI: 10.1194/Jlr.M040618 |
0.321 |
|
| 2013 |
Schilling JD, Machkovech HM, He L, Diwan A, Schaffer JE. TLR4 activation under lipotoxic conditions leads to synergistic macrophage cell death through a TRIF-dependent pathway. Journal of Immunology (Baltimore, Md. : 1950). 190: 1285-96. PMID 23275600 DOI: 10.4049/Jimmunol.1202208 |
0.413 |
|
| 2013 |
Schilling JD, Machkovech HM, He L, Sidhu R, Fujiwara H, Weber K, Ory DS, Schaffer JE. Palmitate and lipopolysaccharide trigger synergistic ceramide production in primary macrophages. The Journal of Biological Chemistry. 288: 2923-32. PMID 23250746 DOI: 10.1074/Jbc.M112.419978 |
0.35 |
|
| 2013 |
Li X, Gonzalez O, Shen X, Barnhart S, Kramer F, Kanter JE, Vivekanandan-Giri A, Tsuchiya K, Handa P, Pennathur S, Kim F, Coleman RA, Schaffer JE, Bornfeldt KE. Endothelial acyl-CoA synthetase 1 is not required for inflammatory and apoptotic effects of a saturated fatty acid-rich environment. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 232-40. PMID 23241406 DOI: 10.1161/Atvbaha.112.252239 |
0.39 |
|
| 2013 |
Crawford PA, Schaffer JE. Metabolic stress in the myocardium: adaptations of gene expression. Journal of Molecular and Cellular Cardiology. 55: 130-8. PMID 22728216 DOI: 10.1016/J.Yjmcc.2012.06.008 |
0.366 |
|
| 2012 |
Schilling JD, Machkovech HM, Kim AH, Schwendener R, Schwedwener R, Schaffer JE. Macrophages modulate cardiac function in lipotoxic cardiomyopathy. American Journal of Physiology. Heart and Circulatory Physiology. 303: H1366-73. PMID 23042950 DOI: 10.1152/Ajpheart.00111.2012 |
0.316 |
|
| 2012 |
Scruggs BS, Michel CI, Ory DS, Schaffer JE. SmD3 regulates intronic noncoding RNA biogenesis. Molecular and Cellular Biology. 32: 4092-103. PMID 22869524 DOI: 10.1128/Mcb.00022-12 |
0.786 |
|
| 2011 |
Michel CI, Holley CL, Scruggs BS, Sidhu R, Brookheart RT, Listenberger LL, Behlke MA, Ory DS, Schaffer JE. Small nucleolar RNAs U32a, U33, and U35a are critical mediators of metabolic stress. Cell Metabolism. 14: 33-44. PMID 21723502 DOI: 10.1016/J.Cmet.2011.04.009 |
0.71 |
|
| 2010 |
Porter FD, Scherrer DE, Lanier MH, Langmade SJ, Molugu V, Gale SE, Olzeski D, Sidhu R, Dietzen DJ, Fu R, Wassif CA, Yanjanin NM, Marso SP, House J, Vite C, ... Schaffer JE, et al. Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease. Science Translational Medicine. 2: 56ra81. PMID 21048217 DOI: 10.1126/Scitranslmed.3001417 |
0.359 |
|
| 2010 |
Ory DS, Schaffer JE. ApoA-1 in diabetes: damaged goods. Diabetes. 59: 2358-9. PMID 20876728 DOI: 10.2337/Db10-1040 |
0.379 |
|
| 2010 |
Ory D, Porter F, Scherrer D, Lanier M, Langmade S, Molugu V, Gale S, Olzeski D, Sidhu R, Wassif C, Yanjanin N, Schaffer J. 99. Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann–Pick C1 disease Molecular Genetics and Metabolism. 99. DOI: 10.1016/J.Ymgme.2009.10.116 |
0.31 |
|
| 2009 |
Liu L, Shi X, Bharadwaj KG, Ikeda S, Yamashita H, Yagyu H, Schaffer JE, Yu YH, Goldberg IJ. DGAT1 expression increases heart triglyceride content but ameliorates lipotoxicity. The Journal of Biological Chemistry. 284: 36312-23. PMID 19778901 DOI: 10.1074/Jbc.M109.049817 |
0.354 |
|
| 2009 |
Brookheart RT, Michel CI, Schaffer JE. As a matter of fat. Cell Metabolism. 10: 9-12. PMID 19583949 DOI: 10.1016/J.Cmet.2009.03.011 |
0.782 |
|
| 2009 |
Brookheart RT, Michel CI, Listenberger LL, Ory DS, Schaffer JE. The non-coding RNA gadd7 is a regulator of lipid-induced oxidative and endoplasmic reticulum stress. The Journal of Biological Chemistry. 284: 7446-54. PMID 19150982 DOI: 10.1074/Jbc.M806209200 |
0.779 |
|
| 2009 |
Gale SE, Westover EJ, Dudley N, Krishnan K, Merlin S, Scherrer DE, Han X, Zhai X, Brockman HL, Brown RE, Covey DF, Schaffer JE, Schlesinger P, Ory DS. Side chain oxygenated cholesterol regulates cellular cholesterol homeostasis through direct sterol-membrane interactions. The Journal of Biological Chemistry. 284: 1755-64. PMID 18996837 DOI: 10.1074/Jbc.M807210200 |
0.409 |
|
| 2008 |
Zhang JR, Coleman T, Langmade SJ, Scherrer DE, Lane L, Lanier MH, Feng C, Sands MS, Schaffer JE, Semenkovich CF, Ory DS. Niemann-Pick C1 protects against atherosclerosis in mice via regulation of macrophage intracellular cholesterol trafficking. The Journal of Clinical Investigation. 118: 2281-90. PMID 18483620 DOI: 10.1172/Jci32561 |
0.392 |
|
| 2008 |
Gelsthorpe ME, Baumann N, Millard E, Gale SE, Langmade SJ, Schaffer JE, Ory DS. Niemann-Pick type C1 I1061T mutant encodes a functional protein that is selected for endoplasmic reticulum-associated degradation due to protein misfolding. The Journal of Biological Chemistry. 283: 8229-36. PMID 18216017 DOI: 10.1074/Jbc.M708735200 |
0.713 |
|
| 2006 |
Borradaile NM, Han X, Harp JD, Gale SE, Ory DS, Schaffer JE. Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death. Journal of Lipid Research. 47: 2726-37. PMID 16960261 DOI: 10.1194/Jlr.M600299-Jlr200 |
0.48 |
|
| 2006 |
Gale SE, Frolov A, Han X, Bickel PE, Cao L, Bowcock A, Schaffer JE, Ory DS. A regulatory role for 1-acylglycerol-3-phosphate-O-acyltransferase 2 in adipocyte differentiation. The Journal of Biological Chemistry. 281: 11082-9. PMID 16495223 DOI: 10.1074/Jbc.M509612200 |
0.388 |
|
| 2006 |
Richards MR, Harp JD, Ory DS, Schaffer JE. Fatty acid transport protein 1 and long-chain acyl coenzyme A synthetase 1 interact in adipocytes. Journal of Lipid Research. 47: 665-72. PMID 16357361 DOI: 10.1194/Jlr.M500514-Jlr200 |
0.494 |
|
| 2006 |
Borradaile NM, Buhman KK, Listenberger LL, Magee CJ, Morimoto ET, Ory DS, Schaffer JE. A critical role for eukaryotic elongation factor 1A-1 in lipotoxic cell death. Molecular Biology of the Cell. 17: 770-8. PMID 16319173 DOI: 10.1091/Mbc.E05-08-0742 |
0.794 |
|
| 2005 |
Borradaile NM, Schaffer JE. Lipotoxicity in the heart. Current Hypertension Reports. 7: 412-7. PMID 16386196 DOI: 10.1007/S11906-005-0035-Y |
0.404 |
|
| 2005 |
Millard EE, Gale SE, Dudley N, Zhang J, Schaffer JE, Ory DS. The sterol-sensing domain of the Niemann-Pick C1 (NPC1) protein regulates trafficking of low density lipoprotein cholesterol. The Journal of Biological Chemistry. 280: 28581-90. PMID 15908696 DOI: 10.1074/Jbc.M414024200 |
0.727 |
|
| 2005 |
Chiu HC, Kovacs A, Blanton RM, Han X, Courtois M, Weinheimer CJ, Yamada KA, Brunet S, Xu H, Nerbonne JM, Welch MJ, Fettig NM, Sharp TL, Sambandam N, Olson KM, ... ... Schaffer JE, et al. Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy. Circulation Research. 96: 225-33. PMID 15618539 DOI: 10.1161/01.Res.0000154079.20681.B9 |
0.382 |
|
| 2004 |
Lee Y, Naseem RH, Duplomb L, Park BH, Garry DJ, Richardson JA, Schaffer JE, Unger RH. Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 101: 13624-9. PMID 15347805 DOI: 10.1073/Pnas.0405499101 |
0.371 |
|
| 2004 |
Kwon G, Pappan KL, Marshall CA, Schaffer JE, McDaniel ML. cAMP Dose-dependently prevents palmitate-induced apoptosis by both protein kinase A- and cAMP-guanine nucleotide exchange factor-dependent pathways in beta-cells. The Journal of Biological Chemistry. 279: 8938-45. PMID 14688288 DOI: 10.1074/Jbc.M310330200 |
0.348 |
|
| 2004 |
Zhang J, Dudley-Rucker N, Crowley JR, Lopez-Perez E, Issandou M, Schaffer JE, Ory DS. The steroidal analog GW707 activates the SREBP pathway through disruption of intracellular cholesterol trafficking. Journal of Lipid Research. 45: 223-31. PMID 14617742 DOI: 10.1194/Jlr.M300409-Jlr200 |
0.406 |
|
| 2003 |
Schaffer JE. Lipotoxicity: when tissues overeat. Current Opinion in Lipidology. 14: 281-7. PMID 12840659 DOI: 10.1097/00041433-200306000-00008 |
0.376 |
|
| 2003 |
Frolov A, Zielinski SE, Crowley JR, Dudley-Rucker N, Schaffer JE, Ory DS. NPC1 and NPC2 regulate cellular cholesterol homeostasis through generation of low density lipoprotein cholesterol-derived oxysterols. The Journal of Biological Chemistry. 278: 25517-25. PMID 12719428 DOI: 10.1074/Jbc.M302588200 |
0.362 |
|
| 2003 |
Moulson CL, Martin DR, Lugus JJ, Schaffer JE, Lind AC, Miner JH. Cloning of wrinkle-free, a previously uncharacterized mouse mutation, reveals crucial roles for fatty acid transport protein 4 in skin and hair development. Proceedings of the National Academy of Sciences of the United States of America. 100: 5274-9. PMID 12697906 DOI: 10.1073/Pnas.0431186100 |
0.338 |
|
| 2003 |
Listenberger LL, Han X, Lewis SE, Cases S, Farese RV, Ory DS, Schaffer JE. Triglyceride accumulation protects against fatty acid-induced lipotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 100: 3077-82. PMID 12629214 DOI: 10.1073/Pnas.0630588100 |
0.762 |
|
| 2003 |
Richards MR, Listenberger LL, Kelly AA, Lewis SE, Ory DS, Schaffer JE. Oligomerization of the murine fatty acid transport protein 1. The Journal of Biological Chemistry. 278: 10477-83. PMID 12533547 DOI: 10.1074/Jbc.M212469200 |
0.757 |
|
| 2003 |
Buhman KK, Newberry EP, Schaffer JE, Chao EH, Davidson NO. The ATP binding domain of fatty acid transport protein (FATP) 4, but not FATP2 is essential for long chain fatty acid import Gastroenterology. 124: A432. DOI: 10.1016/S0016-5085(03)82180-7 |
0.336 |
|
| 2002 |
Listenberger LL, Schaffer JE. Mechanisms of lipoapoptosis: implications for human heart disease. Trends in Cardiovascular Medicine. 12: 134-8. PMID 12007739 DOI: 10.1016/S1050-1738(02)00152-4 |
0.749 |
|
| 2002 |
Schaffer JE. Fatty acid transport: the roads taken. American Journal of Physiology. Endocrinology and Metabolism. 282: E239-46. PMID 11788354 DOI: 10.1152/Ajpendo.00462.2001 |
0.412 |
|
| 2002 |
Souza SC, Muliro KV, Liscum L, Lien P, Yamamoto MT, Schaffer JE, Dallal GE, Wang X, Kraemer FB, Obin M, Greenberg AS. Modulation of hormone-sensitive lipase and protein kinase A-mediated lipolysis by perilipin A in an adenoviral reconstituted system. The Journal of Biological Chemistry. 277: 8267-72. PMID 11751901 DOI: 10.1074/Jbc.M108329200 |
0.38 |
|
| 2001 |
Frolov A, Srivastava K, Daphna-Iken D, Traub LM, Schaffer JE, Ory DS. Cholesterol Overload Promotes Morphogenesis of a Niemann-Pick C (NPC)-like Compartment Independent of Inhibition of NPC1 or HE1/NPC2 Function Journal of Biological Chemistry. 276: 46414-46421. PMID 11571306 DOI: 10.1074/Jbc.M108099200 |
0.37 |
|
| 2001 |
Lewis SE, Listenberger LL, Ory DS, Schaffer JE. Membrane topology of the murine fatty acid transport protein 1. The Journal of Biological Chemistry. 276: 37042-50. PMID 11470793 DOI: 10.1074/Jbc.M105556200 |
0.73 |
|
| 2001 |
Chiu HC, Kovacs A, Ford DA, Hsu FF, Garcia R, Herrero P, Saffitz JE, Schaffer JE. A novel mouse model of lipotoxic cardiomyopathy Journal of Clinical Investigation. 107: 813-822. PMID 11285300 DOI: 10.1172/Jci10947 |
0.413 |
|
| 2001 |
Listenberger LL, Ory DS, Schaffer JE. Palmitate-induced apoptosis can occur through a ceramide-independent pathway. The Journal of Biological Chemistry. 276: 14890-5. PMID 11278654 DOI: 10.1074/Jbc.M010286200 |
0.76 |
|
| 2000 |
Millard EE, Srivastava K, Traub LM, Schaffer JE, Ory DS. Niemann-pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis. The Journal of Biological Chemistry. 275: 38445-51. PMID 10964915 DOI: 10.1074/Jbc.M003180200 |
0.729 |
|
| 1999 |
Stuhlsatz-Krouper SM, Bennett NE, Schaffer JE. Molecular aspects of fatty acid transport: Mutations in the IYTSGTTGXPK motif impair fatty acid transport protein function Prostaglandins Leukotrienes and Essential Fatty Acids. 60: 285-289. PMID 10471110 DOI: 10.1016/S0952-3278(99)80001-5 |
0.366 |
|
| 1998 |
Stuhlsatz-Krouper SM, Bennett NE, Schaffer JE. Substitution of alanine for serine 250 in the murine fatty acid transport protein inhibits long chain fatty acid transport Journal of Biological Chemistry. 273: 28642-28650. PMID 9786857 DOI: 10.1074/Jbc.273.44.28642 |
0.356 |
|
| 1998 |
Hui TY, Frohnert BI, Smith AJ, Schaffer JE, Bernlohr DA. Characterization of the murine fatty acid transport protein gene and its insulin response sequence. The Journal of Biological Chemistry. 273: 27420-9. PMID 9765271 DOI: 10.1074/Jbc.273.42.27420 |
0.379 |
|
| 1996 |
Man MZ, Hui TY, Schaffer JE, Lodish HF, Bernlohr DA. Regulation of the murine adipocyte fatty acid transporter gene by insulin Molecular Endocrinology. 10: 1021-1028. PMID 8843418 DOI: 10.1210/Mend.10.8.8843418 |
0.465 |
|
| 1995 |
Schaffer JE, Lodish HF. Molecular mechanism of long-chain fatty acid uptake Trends in Cardiovascular Medicine. 5: 218-224. DOI: 10.1016/1050-1738(95)00102-6 |
0.544 |
|
| 1994 |
Schaffer JE, Lodish HF. Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein Cell. 79: 427-436. PMID 7954810 DOI: 10.1016/0092-8674(94)90252-6 |
0.527 |
|
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