Xiang-Dong Fu - Publications

University of California, San Diego, La Jolla, CA 
Cell Biology, Molecular Biology, Biochemistry

183 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Qian H, Kang X, Hu J, Zhang D, Liang Z, Meng F, Zhang X, Xue Y, Maimon R, Dowdy SF, Devaraj NK, Zhou Z, Mobley WC, Cleveland DW, Fu XD. Reversing a model of Parkinson's disease with in situ converted nigral neurons. Nature. 582: 550-556. PMID 32581380 DOI: 10.1038/s41586-020-2388-4  1
2020 López-Erauskin J, Tadokoro T, Baughn MW, Myers B, McAlonis-Downes M, Chillon-Marinas C, Asiaban JN, Artates J, Bui AT, Vetto AP, Lee SK, Le AV, Sun Y, Jambeau M, Boubaker J, ... ... Fu XD, et al. ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS. Neuron. 106: 354. PMID 32325059 DOI: 10.1016/j.neuron.2020.04.006  0.8
2020 Van Nostrand EL, Pratt GA, Yee BA, Wheeler EC, Blue SM, Mueller J, Park SS, Garcia KE, Gelboin-Burkhart C, Nguyen TB, Rabano I, Stanton R, Sundararaman B, Wang R, Fu XD, et al. Principles of RNA processing from analysis of enhanced CLIP maps for 150 RNA binding proteins. Genome Biology. 21: 90. PMID 32252787 DOI: 10.1186/s13059-020-01982-9  0.4
2020 Gou LT, Lim DH, Ma W, Aubol BE, Hao Y, Wang X, Zhao J, Liang Z, Shao C, Zhang X, Meng F, Li H, Zhang X, Xu R, Li D, ... ... Fu XD, et al. Initiation of Parental Genome Reprogramming in Fertilized Oocyte by Splicing Kinase SRPK1-Catalyzed Protamine Phosphorylation. Cell. PMID 32169215 DOI: 10.1016/j.cell.2020.02.020  1
2020 Zhou B, Li X, Luo D, Lim DH, Zhou Y, Fu XD. Author Correction: GRID-seq for comprehensive analysis of global RNA-chromatin interactions. Nature Protocols. PMID 32060493 DOI: 10.1038/s41596-020-0308-6  0.92
2020 Fan JB, Miyauchi S, Xu HZ, Liu D, Kim LJY, Burkart C, Cheng H, Arimoto KI, Yan M, Zhou Y, Gyorffy B, Knobeloch KP, Rich JN, Cang H, Fu XD, et al. Type I Interferon Regulates a Coordinated Gene Network to Enhance Cytotoxic T Cell-Mediated Tumor Killing. Cancer Discovery. PMID 31974171 DOI: 10.1158/2159-8290.CD-19-0608  0.8
2020 Chen JY, Lim DH, Fu XD. Mechanistic Dissection of RNA-Binding Proteins in Regulated Gene Expression at Chromatin Levels. Cold Spring Harbor Symposia On Quantitative Biology. PMID 31900328 DOI: 10.1101/sqb.2019.84.039222  0.92
2019 Wang G, Luo X, Liang Y, Kaneko K, Li H, Fu XD, Feng GS. A tumorigenic index for quantitative analysis of liver cancer initiation and progression. Proceedings of the National Academy of Sciences of the United States of America. PMID 31843886 DOI: 10.1073/pnas.1911193116  0.8
2019 Dai P, Wang X, Gou LT, Li ZT, Wen Z, Chen ZG, Hua MM, Zhong A, Wang L, Su H, Wan H, Qian K, Liao L, Li J, Tian B, ... ... Fu XD, et al. A Translation-Activating Function of MIWI/piRNA during Mouse Spermiogenesis. Cell. 179: 1566-1581.e16. PMID 31835033 DOI: 10.1016/j.cell.2019.11.022  0.8
2019 Hu WJ, Ling HQ, Fu XD. [Development and application of the plant phenomics analysis platform]. Yi Chuan = Hereditas. 41: 1060-1066. PMID 31735708 DOI: 10.16288/j.yczz.19-277  0.52
2019 Li H, Fan J, Zhao Y, Zhang X, Dai B, Zhan J, Yin Z, Nie X, Fu XD, Chen C, Wang DW. Nuclear miR-320 Mediates Diabetes-Induced Cardiac Dysfunction by Activating Transcription of Fatty Acid Metabolic Genes to Cause Lipotoxicity in the Heart. Circulation Research. PMID 31638474 DOI: 10.1161/CIRCRESAHA.119.314898  0.8
2019 Li X, Fu XD. Author Correction: Chromatin-associated RNAs as facilitators of functional genomic interactions. Nature Reviews. Genetics. PMID 31273305 DOI: 10.1038/s41576-019-0155-x  0.8
2019 Xiao R, Chen JY, Liang Z, Luo D, Chen G, Lu ZJ, Chen Y, Zhou B, Li H, Du X, Yang Y, San M, Wei X, Liu W, Lécuyer E, ... ... Fu XD, et al. Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription. Cell. 178: 107-121.e18. PMID 31251911 DOI: 10.1016/j.cell.2019.06.001  0.92
2019 Zhou B, Li X, Luo D, Lim DH, Zhou Y, Fu XD. GRID-seq for comprehensive analysis of global RNA-chromatin interactions. Nature Protocols. PMID 31175345 DOI: 10.1038/s41596-019-0172-4  0.92
2019 Li X, Fu XD. Chromatin-associated RNAs as facilitators of functional genomic interactions. Nature Reviews. Genetics. PMID 31160792 DOI: 10.1038/s41576-019-0135-1  0.8
2019 Chen JY, Zhang X, Fu XD, Chen L. R-ChIP for genome-wide mapping of R-loops by using catalytically inactive RNASEH1. Nature Protocols. PMID 30996261 DOI: 10.1038/s41596-019-0154-6  0.92
2019 Liu C, Spinozzi S, Chen JY, Fang X, Feng W, Perkins G, Cattaneo P, Guimarães-Camboa N, Dalton ND, Peterson KL, Wu T, Ouyang K, Fu XD, Evans SM, Chen J. Nexilin is a New Component of Junctional Membrane Complexes Required for Cardiac T-Tubule Formation. Circulation. PMID 30982350 DOI: 10.1161/CIRCULATIONAHA.119.039751  0.92
2019 Hu J, Gao C, Wei C, Xue Y, Shao C, Hao Y, Gou LT, Zhou Y, Zhang J, Ren S, Chen J, Wang Y, Fu XD. RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure. Proceedings of the National Academy of Sciences of the United States of America. PMID 30867288 DOI: 10.1073/pnas.1822176116  0.8
2018 López-Erauskin J, Tadokoro T, Baughn MW, Myers B, McAlonis-Downes M, Chillon-Marinas C, Asiaban JN, Artates J, Bui AT, Vetto AP, Lee SK, Le AV, Sun Y, Jambeau M, Boubaker J, ... ... Fu XD, et al. ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS. Neuron. PMID 30344044 DOI: 10.1016/j.neuron.2018.09.044  0.8
2018 Hu J, Qian H, Xue Y, Fu XD. PTB/nPTB: master regulators of neuronal fate in mammals. Biophysics Reports. 4: 204-214. PMID 30310857 DOI: 10.1007/s41048-018-0066-y  0.8
2018 Zhang K, Zhang X, Cai Z, Zhou J, Cao R, Zhao Y, Chen Z, Wang D, Ruan W, Zhao Q, Liu G, Xue Y, Qin Y, Zhou B, Wu L, ... ... Fu XD, et al. A novel class of microRNA-recognition elements that function only within open reading frames. Nature Structural & Molecular Biology. PMID 30297778 DOI: 10.1038/s41594-018-0136-3  0.8
2018 Zhou Z, Qiu J, Liu W, Zhou Y, Plocinik RM, Li H, Hu Q, Ghosh G, Adams JA, Rosenfeld MG, Fu XD. The Akt-SRPK-SR Axis Constitutes a Major Pathway in Transducing EGF Signaling to Regulate Alternative Splicing in the Nucleus. Molecular Cell. 71: 872. PMID 30193100 DOI: 10.1016/j.molcel.2018.08.024  1
2018 Hatcher JM, Wu G, Zeng C, Zhu J, Meng F, Patel S, Wang W, Ficarro SB, Leggett AL, Powell CE, Marto JA, Zhang K, Ki Ngo JC, Fu XD, Zhang T, et al. SRPKIN-1: A Covalent SRPK1/2 Inhibitor that Potently Converts VEGF from Pro-angiogenic to Anti-angiogenic Isoform. Cell Chemical Biology. PMID 29478907 DOI: 10.1016/j.chembiol.2018.01.013  0.72
2018 Bao X, Guo X, Yin M, Tariq M, Lai Y, Kanwal S, Zhou J, Li N, Lv Y, Pulido-Quetglas C, Wang X, Ji L, Khan MJ, Zhu X, Luo Z, ... ... Fu XD, et al. Capturing the interactome of newly transcribed RNA. Nature Methods. PMID 29431736 DOI: 10.1038/nmeth.4595  0.92
2018 Chen L, Chen JY, Huang YJ, Gu Y, Qiu J, Qian H, Shao C, Zhang X, Hu J, Li H, He S, Zhou Y, Abdel-Wahab O, Zhang DE, Fu XD. The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations. Molecular Cell. 69: 412-425.e6. PMID 29395063 DOI: 10.1016/j.molcel.2017.12.029  0.92
2017 Ouyang H, Zhang K, Fox-Walsh K, Yang Y, Zhang C, Huang J, Li H, Zhou Y, Fu XD. The RNA binding protein EWS is broadly involved in the regulation of pri-miRNA processing in mammalian cells. Nucleic Acids Research. 45: 12481-12495. PMID 30053258 DOI: 10.1093/nar/gkx912  0.8
2017 Liang Y, Feng Y, Zong M, Wei X, Lee J, Feng Y, Li H, Yang G, Wu ZJ, Fu XD, Feng GS. β-Catenin Deficiency in Hepatocytes Aggravates Hepatocarcinogenesis Driven by Oncogenic β-Catenin and MET. Hepatology (Baltimore, Md.). PMID 29152756 DOI: 10.1002/hep.29661  0.8
2017 Chen L, Chen JY, Zhang X, Gu Y, Xiao R, Shao C, Tang P, Qian H, Luo D, Li H, Zhou Y, Zhang DE, Fu XD. R-ChIP Using Inactive RNase H Reveals Dynamic Coupling of R-loops with Transcriptional Pausing at Gene Promoters. Molecular Cell. PMID 29104020 DOI: 10.1016/j.molcel.2017.10.008  0.92
2017 Li Q, Zheng S, Han A, Lin CH, Stoilov P, Fu XD, Black DL. Correction: The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation. Elife. 6. PMID 28990924 DOI: 10.7554/eLife.31550  0.52
2017 Li X, Zhou B, Chen L, Gou LT, Li H, Fu XD. GRID-seq reveals the global RNA-chromatin interactome. Nature Biotechnology. PMID 28922346 DOI: 10.1038/nbt.3968  0.8
2017 Jiang L, Shao C, Wu QJ, Chen G, Zhou J, Yang B, Li H, Gou LT, Zhang Y, Wang Y, Yeo GW, Zhou Y, Fu XD. NEAT1 scaffolds RNA-binding proteins and the Microprocessor to globally enhance pri-miRNA processing. Nature Structural & Molecular Biology. PMID 28846091 DOI: 10.1038/nsmb.3455  0.8
2017 Gou LT, Kang JY, Dai P, Wang X, Li F, Zhao S, Zhang M, Hua MM, Lu Y, Zhu Y, Li Z, Chen H, Wu LG, Li D, Fu XD, et al. Ubiquitination-Deficient Mutations in Human Piwi Cause Male Infertility by Impairing Histone-to-Protamine Exchange during Spermiogenesis. Cell. PMID 28552346 DOI: 10.1016/j.cell.2017.04.034  0.8
2016 Yi J, Shen HF, Qiu JS, Huang MF, Zhang WJ, Ding JC, Zhu XY, Zhou Y, Fu XD, Liu W. JMJD6 and U2AF65 co-regulate alternative splicing in both JMJD6 enzymatic activity dependent and independent manner. Nucleic Acids Research. PMID 27899633 DOI: 10.1093/nar/gkw1144  0.8
2016 Lim SM, Choi BO, Oh SI, Choi WJ, Oh KW, Nahm M, Xue Y, Choi JH, Choi JY, Kim YE, Chung KW, Fu XD, Ki CS, Kim SH. Patient fibroblasts-derived induced neurons demonstrate autonomous neuronal defects in adult-onset Krabbe disease. Oncotarget. PMID 27780934 DOI: 10.18632/oncotarget.12812  0.72
2016 Zhu K, Lei PJ, Ju LG, Wang X, Huang K, Yang B, Shao C, Zhu Y, Wei G, Fu XD, Li L, Wu M. SPOP-containing complex regulates SETD2 stability and H3K36me3-coupled alternative splicing. Nucleic Acids Research. PMID 27614073 DOI: 10.1093/nar/gkw814  0.8
2016 Li H, Zhang X, Wang F, Zhou L, Yin Z, Fan J, Nie X, Wang P, Fu XD, Chen C, Wang D. MiR-21 Lowers Blood Pressure in Spontaneous Hypertensive Rats By Up-Regulating Mitochondrial Translation. Circulation. PMID 27542393 DOI: 10.1161/CIRCULATIONAHA.116.023926  0.48
2016 Qiu J, Zhou B, Thol F, Zhou Y, Chen L, Shao C, DeBoever C, Hou J, Li H, Chaturvedi A, Ganser A, Bejar R, Zhang DE, Fu XD, Heuser M. Distinct splicing signatures affect converged pathways in myelodysplastic syndrome patients carrying mutations in different splicing regulators. Rna (New York, N.Y.). PMID 27492256 DOI: 10.1261/rna.056101.116  0.8
2016 Aubol BE, Wu G, Keshwani MM, Movassat M, Fattet L, Hertel KJ, Fu XD, Adams JA. Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing. Molecular Cell. PMID 27397683 DOI: 10.1016/j.molcel.2016.05.034  1
2016 Wei C, Xiao R, Chen L, Cui H, Zhou Y, Xue Y, Hu J, Zhou B, Tsutsui T, Qiu J, Li H, Tang L, Fu XD. RBFox2 Binds Nascent RNA to Globally Regulate Polycomb Complex 2 Targeting in Mammalian Genomes. Molecular Cell. 62: 982. PMID 27315558 DOI: 10.1016/j.molcel.2016.06.003  0.8
2016 Chen L, Liu Z, Zhou B, Wei C, Zhou Y, Rosenfeld MG, Fu XD, Chisholm AD, Jin Y. CELF RNA binding proteins promote axon regeneration in C. elegans and mammals through alternative splicing of Syntaxins. Elife. 5. PMID 27253061 DOI: 10.7554/eLife.16072  0.8
2016 Wei C, Xiao R, Chen L, Cui H, Zhou Y, Xue Y, Hu J, Zhou B, Tsutsui T, Qiu J, Li H, Fu XD. RBFox2 Binds Nascent RNA to Globally Regulate Polycomb Complex 2 Targeting in Mammalian Genomes. Molecular Cell. PMID 27211866 DOI: 10.1016/j.molcel.2016.04.013  0.8
2016 Xue Y, Qian H, Hu J, Zhou B, Zhou Y, Hu X, Karakhanyan A, Pang Z, Fu XD. Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells. Nature Neuroscience. PMID 27110916 DOI: 10.1038/nn.4297  0.68
2016 Scekic-Zahirovic J, Sendscheid O, El Oussini H, Jambeau M, Sun Y, Mersmann S, Wagner M, Dieterlé S, Sinniger J, Dirrig-Grosch S, Drenner K, Birling MC, Qiu J, Zhou Y, Li H, ... Fu XD, et al. Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss. The Embo Journal. PMID 26951610 DOI: 10.15252/embj.201592559  0.4
2016 Zhang ZN, Freitas BC, Qian H, Lux J, Acab A, Trujillo CA, Herai RH, Nguyen Huu VA, Wen JH, Joshi-Barr S, Karpiak JV, Engler AJ, Fu XD, Muotri AR, Almutairi A. Layered hydrogels accelerate iPSC-derived neuronal maturation and reveal migration defects caused by MeCP2 dysfunction. Proceedings of the National Academy of Sciences of the United States of America. PMID 26944080 DOI: 10.1073/pnas.1521255113  0.6
2016 Lim SM, Choi WJ, Oh KW, Xue Y, Choi JY, Kim SH, Nahm M, Kim YE, Lee J, Noh MY, Lee S, Hwang S, Ki CS, Fu XD, Kim SH. Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis. Molecular Neurodegeneration. 11: 8. PMID 26795035 DOI: 10.1186/s13024-016-0075-6  1
2016 Hu J, Sun T, Wang H, Chen Z, Wang S, Yuan L, Liu T, Li HR, Wang P, Feng Y, Wang Q, McLendon RE, Friedman AH, Keir ST, Bigner DD, ... ... Fu XD, et al. MiR-215 Is Induced Post-transcriptionally via HIF-Drosha Complex and Mediates Glioma-Initiating Cell Adaptation to Hypoxia by Targeting KDM1B. Cancer Cell. 29: 49-60. PMID 26766590 DOI: 10.1016/j.ccell.2015.12.005  1
2015 Marina RJ, Fu XD. Diabetic Insult-Induced Redistribution of MicroRNA in Spatially Organized Mitochondria in Cardiac Muscle. Circulation. Cardiovascular Genetics. 8: 747-8. PMID 26671968 DOI: 10.1161/CIRCGENETICS.115.001258  0.4
2015 Gao C, Ren S, Lee JH, Qiu J, Chapski DJ, Rau CD, Zhou Y, Abdellatif M, Nakano A, Vondriska TM, Xiao X, Fu XD, Chen JN, Wang Y. RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure. The Journal of Clinical Investigation. PMID 26619120 DOI: 10.1172/JCI84015  1
2015 Chen F, Zhou Y, Qi YB, Khivansara V, Li H, Chun SY, Kim JK, Fu XD, Jin Y. Context-dependent modulation of Pol II CTD phosphatase SSUP-72 regulates alternative polyadenylation in neuronal development. Genes & Development. 29: 2377-90. PMID 26588990 DOI: 10.1101/gad.266650.115  0.52
2015 Martinez NM, Agosto L, Qiu J, Mallory MJ, Gazzara MR, Barash Y, Fu XD, Lynch KW. Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation. Genes & Development. 29: 2054-66. PMID 26443849 DOI: 10.1101/gad.267245.115  0.8
2015 Cole BS, Tapescu I, Allon SJ, Mallory MJ, Qiu J, Lake RJ, Fan HY, Fu XD, Lynch KW. Global analysis of physical and functional RNA targets of hnRNP L reveals distinct sequence and epigenetic features of repressed and enhanced exons. Rna (New York, N.Y.). PMID 26437669 DOI: 10.1261/rna.052969.115  0.8
2015 Tang FC, Wang HY, Ma MM, Guan TW, Pan L, Yao DC, Chen YL, Chen WB, Tu YS, Fu XD. CyPA-CD147-ERK1/2-cyclin D2 signaling pathway is upregulated during rat left ventricular hypertrophy. Sheng Li Xue Bao : [Acta Physiologica Sinica]. 67: 393-400. PMID 26300251  0.88
2015 Yarosh CA, Tapescu I, Thompson MG, Qiu J, Mallory MJ, Fu XD, Lynch KW. TRAP150 interacts with the RNA-binding domain of PSF and antagonizes splicing of numerous PSF-target genes in T cells. Nucleic Acids Research. PMID 26261210 DOI: 10.1093/nar/gkv816  0.8
2015 Komeno Y, Huang YJ, Qiu J, Lin L, Xu Y, Zhou Y, Chen L, Monterroza DD, Li H, DeKelver RC, Yan M, Fu XD, Zhang DE. SRSF2 is essential for hematopoiesis and its myelodysplastic syndromes-related mutations dysregulate alternative pre-mRNA splicing. Molecular and Cellular Biology. PMID 26124281 DOI: 10.1128/MCB.00202-15  1
2015 Wang L, Zhou Y, Xu L, Xiao R, Lu X, Chen L, Chong J, Li H, He C, Fu XD, Wang D. Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex. Nature. PMID 26123024 DOI: 10.1038/nature14482  1
2015 Cai Z, Cao R, Zhang K, Xue Y, Zhang C, Zhou Y, Zhou J, Sun H, Fu XD. Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote Tumorigenesis. The Journal of Biological Chemistry. PMID 26117336 DOI: 10.1074/jbc.M115.661504  1
2015 Li G, Xu F, Zhu J, Krawczyk M, Zhang Y, Yuan J, Patel S, Wang Y, Lin Y, Zhang M, Cai H, Chen D, Zhang M, Cao G, Yeh E, ... ... Fu XD, et al. Transcription factor Paired Box 6 controls limbal stem cell lineage in development and disease. The Journal of Biological Chemistry. PMID 26045558 DOI: 10.1074/jbc.M115.662940  0.6
2015 Wu T, Fu XD. Genomic functions of U2AF in constitutive and regulated splicing. Rna Biology. 12: 479-85. PMID 25901584 DOI: 10.1080/15476286.2015.1020272  0.6
2015 Mallory MJ, Allon SJ, Qiu J, Gazzara MR, Tapescu I, Martinez NM, Fu XD, Lynch KW. Induced transcription and stability of CELF2 mRNA drives widespread alternative splicing during T-cell signaling. Proceedings of the National Academy of Sciences of the United States of America. 112: E2139-48. PMID 25870297 DOI: 10.1073/pnas.1423695112  0.8
2015 Chang AT, Liu Y, Ayyanathan K, Benner C, Jiang Y, Prokop JW, Paz H, Wang D, Li HR, Fu XD, Rauscher FJ, Yang J. An evolutionarily conserved DNA architecture determines target specificity of the TWIST family bHLH transcription factors. Genes & Development. 29: 603-16. PMID 25762439 DOI: 10.1101/gad.242842.114  0.52
2015 Wei C, Qiu J, Zhou Y, Xue Y, Hu J, Ouyang K, Banerjee I, Zhang C, Chen B, Li H, Chen J, Song LS, Fu XD. Repression of the Central Splicing Regulator RBFox2 Is Functionally Linked to Pressure Overload-Induced Heart Failure. Cell Reports. PMID 25753418 DOI: 10.1016/j.celrep.2015.02.013  1
2015 Gou LT, Dai P, Yang JH, Xue Y, Hu YP, Zhou Y, Kang JY, Wang X, Li H, Hua MM, Zhao S, Hu SD, Wu LG, Shi HJ, Li Y, ... Fu XD, et al. Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis. Cell Research. 25: 266. PMID 25645811 DOI: 10.1038/cr.2015.14  0.8
2015 Sun S, Ling SC, Qiu J, Albuquerque CP, Zhou Y, Tokunaga S, Li H, Qiu H, Bui A, Yeo GW, Huang EJ, Eggan K, Zhou H, Fu XD, Lagier-Tourenne C, et al. ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP. Nature Communications. 6: 6171. PMID 25625564 DOI: 10.1038/ncomms7171  1
2015 Zhang P, Kang JY, Gou LT, Wang J, Xue Y, Skogerboe G, Dai P, Huang DW, Chen R, Fu XD, Liu MF, He S. MIWI and piRNA-mediated cleavage of messenger RNAs in mouse testes. Cell Research. 25: 193-207. PMID 25582079 DOI: 10.1038/cr.2015.4  0.8
2015 Keshwani MM, Aubol BE, Fattet L, Ma CT, Qiu J, Jennings PA, Fu XD, Adams JA. Conserved proline-directed phosphorylation regulates SR protein conformation and splicing function. The Biochemical Journal. 466: 311-22. PMID 25529026 DOI: 10.1042/BJ20141373  1
2014 Fong N, Kim H, Zhou Y, Ji X, Qiu J, Saldi T, Diener K, Jones K, Fu XD, Bentley DL. Pre-mRNA splicing is facilitated by an optimal RNA polymerase II elongation rate. Genes & Development. 28: 2663-76. PMID 25452276 DOI: 10.1101/gad.252106.114  0.4
2014 Shao C, Yang B, Wu T, Huang J, Tang P, Zhou Y, Zhou J, Qiu J, Jiang L, Li H, Chen G, Sun H, Zhang Y, Denise A, Zhang DE, ... Fu XD, et al. Mechanisms for U2AF to define 3' splice sites and regulate alternative splicing in the human genome. Nature Structural & Molecular Biology. 21: 997-1005. PMID 25326705 DOI: 10.1038/nsmb.2906  1
2014 Liu Y, Xue Y, Ridley S, Zhang D, Rezvani K, Fu XD, Wang H. Direct reprogramming of Huntington's disease patient fibroblasts into neuron-like cells leads to abnormal neurite outgrowth, increased cell death, and aggregate formation. Plos One. 9: e109621. PMID 25275533 DOI: 10.1371/journal.pone.0109621  1
2014 Fu XD, Ares M. Context-dependent control of alternative splicing by RNA-binding proteins. Nature Reviews. Genetics. 15: 689-701. PMID 25112293 DOI: 10.1038/nrg3778  1
2014 Zhang X, Zuo X, Yang B, Li Z, Xue Y, Zhou Y, Huang J, Zhao X, Zhou J, Yan Y, Zhang H, Guo P, Sun H, Guo L, Zhang Y, ... Fu XD, et al. MicroRNA directly enhances mitochondrial translation during muscle differentiation. Cell. 158: 607-19. PMID 25083871 DOI: 10.1016/j.cell.2014.05.047  1
2014 Ouyang H, Xue Y, Lin Y, Zhang X, Xi L, Patel S, Cai H, Luo J, Zhang M, Zhang M, Yang Y, Li G, Li H, Jiang W, Yeh E, ... ... Fu XD, et al. WNT7A and PAX6 define corneal epithelium homeostasis and pathogenesis. Nature. 511: 358-61. PMID 25030175 DOI: 10.1038/nature13465  1
2014 Aubol BE, Plocinik RM, Keshwani MM, McGlone ML, Hagopian JC, Ghosh G, Fu XD, Adams JA. N-terminus of the protein kinase CLK1 induces SR protein hyperphosphorylation. The Biochemical Journal. 462: 143-52. PMID 24869919 DOI: 10.1042/BJ20140494  1
2014 Gou LT, Dai P, Yang JH, Xue Y, Hu YP, Zhou Y, Kang JY, Wang X, Li H, Hua MM, Zhao S, Hu SD, Wu LG, Shi HJ, Li Y, ... Fu XD, et al. Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis. Cell Research. 24: 680-700. PMID 24787618 DOI: 10.1038/cr.2014.41  1
2014 Schaffer AE, Eggens VR, Caglayan AO, Reuter MS, Scott E, Coufal NG, Silhavy JL, Xue Y, Kayserili H, Yasuno K, Rosti RO, Abdellateef M, Caglar C, Kasher PR, Cazemier JL, ... ... Fu XD, et al. CLP1 founder mutation links tRNA splicing and maturation to cerebellar development and neurodegeneration. Cell. 157: 651-63. PMID 24766810 DOI: 10.1016/j.cell.2014.03.049  1
2014 Wang P, Zhou Z, Hu A, Ponte de Albuquerque C, Zhou Y, Hong L, Sierecki E, Ajiro M, Kruhlak M, Harris C, Guan KL, Zheng ZM, Newton AC, Sun P, Zhou H, ... Fu XD, et al. Both decreased and increased SRPK1 levels promote cancer by interfering with PHLPP-mediated dephosphorylation of Akt. Molecular Cell. 54: 378-91. PMID 24703948 DOI: 10.1016/j.molcel.2014.03.007  1
2014 Zhou Y, Li HR, Huang J, Jin G, Fu XD. Multiplex analysis of polyA-linked sequences (MAPS): an RNA-seq strategy to profile poly(A+) RNA. Methods in Molecular Biology (Clifton, N.J.). 1125: 169-78. PMID 24590789 DOI: 10.1007/978-1-62703-971-0_15  1
2014 Han A, Stoilov P, Linares AJ, Zhou Y, Fu XD, Black DL. De novo prediction of PTBP1 binding and splicing targets reveals unexpected features of its RNA recognition and function. Plos Computational Biology. 10: e1003442. PMID 24499931 DOI: 10.1371/journal.pcbi.1003442  1
2014 Li Q, Zheng S, Han A, Lin CH, Stoilov P, Fu XD, Black DL. The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation. Elife. 3: e01201. PMID 24448406 DOI: 10.7554/eLife.01201  0.44
2014 Fu X, Shen Y. Study of collective user behaviour in twitter: A fuzzy approach Neural Computing and Applications. 25: 1603-1614. DOI: 10.1007/s00521-014-1642-9  1
2013 Mo S, Ji X, Fu XD. Unique role of SRSF2 in transcription activation and diverse functions of the SR and hnRNP proteins in gene expression regulation. Transcription. 4: 251-9. PMID 24406341  0.72
2013 Lagier-Tourenne C, Baughn M, Rigo F, Sun S, Liu P, Li HR, Jiang J, Watt AT, Chun S, Katz M, Qiu J, Sun Y, Ling SC, Zhu Q, Polymenidou M, ... ... Fu XD, et al. Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration. Proceedings of the National Academy of Sciences of the United States of America. 110: E4530-9. PMID 24170860 DOI: 10.1073/pnas.1318835110  1
2013 Fu XD, Sun XQ, Wang HY, Guo JF, Zhang GZ, Xu QH. Genetic polymorphisms of the TLR4 gene and their association with susceptibility to type 2 diabetes mellitus in the Chinese population. Genetics and Molecular Research : Gmr. 12: 3813-20. PMID 24085443 DOI: 10.4238/2013.September.19.13  0.88
2013 Yoshioka N, Gros E, Li HR, Kumar S, Deacon DC, Maron C, Muotri AR, Chi NC, Fu XD, Yu BD, Dowdy SF. Efficient generation of human iPSCs by a synthetic self-replicative RNA. Cell Stem Cell. 13: 246-54. PMID 23910086 DOI: 10.1016/j.stem.2013.06.001  1
2013 Aubol BE, Plocinik RM, Hagopian JC, Ma CT, McGlone ML, Bandyopadhyay R, Fu XD, Adams JA. Partitioning RS domain phosphorylation in an SR protein through the CLK and SRPK protein kinases. Journal of Molecular Biology. 425: 2894-909. PMID 23707382 DOI: 10.1016/j.jmb.2013.05.013  1
2013 Ji X, Zhou Y, Pandit S, Huang J, Li H, Lin CY, Xiao R, Burge CB, Fu XD. SR proteins collaborate with 7SK and promoter-associated nascent RNA to release paused polymerase. Cell. 153: 855-68. PMID 23663783 DOI: 10.1016/j.cell.2013.04.028  1
2013 Wang Y, Jiang L, Ji X, Yang B, Zhang Y, Fu XD. Hepatitis B viral RNA directly mediates down-regulation of the tumor suppressor microRNA miR-15a/miR-16-1 in hepatocytes. The Journal of Biological Chemistry. 288: 18484-93. PMID 23649629 DOI: 10.1074/jbc.M113.458158  0.76
2013 Pandit S, Zhou Y, Shiue L, Coutinho-Mansfield G, Li H, Qiu J, Huang J, Yeo GW, Ares M, Fu XD. Genome-wide analysis reveals SR protein cooperation and competition in regulated splicing. Molecular Cell. 50: 223-35. PMID 23562324 DOI: 10.1016/j.molcel.2013.03.001  1
2013 Zhou Z, Fu XD. Regulation of splicing by SR proteins and SR protein-specific kinases. Chromosoma. 122: 191-207. PMID 23525660 DOI: 10.1007/s00412-013-0407-z  1
2013 Xue Y, Ouyang K, Huang J, Zhou Y, Ouyang H, Li H, Wang G, Wu Q, Wei C, Bi Y, Jiang L, Cai Z, Sun H, Zhang K, Zhang Y, ... ... Fu XD, et al. Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated MicroRNA circuits Cell. 152: 82-96. PMID 23313552 DOI: 10.1016/j.cell.2012.11.045  1
2012 Dembowski JA, An P, Scoulos-Hanson M, Yeo G, Han J, Fu XD, Grabowski PJ. Alternative Splicing of a Novel Inducible Exon Diversifies the CASK Guanylate Kinase Domain. Journal of Nucleic Acids. 2012: 816237. PMID 23008758 DOI: 10.1155/2012/816237  1
2012 Yu FX, Zhao B, Panupinthu N, Jewell JL, Lian I, Wang LH, Zhao J, Yuan H, Tumaneng K, Li H, Fu XD, Mills GB, Guan KL. Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling. Cell. 150: 780-91. PMID 22863277 DOI: 10.1016/j.cell.2012.06.037  1
2012 Tripathi V, Song DY, Zong X, Shevtsov SP, Hearn S, Fu XD, Dundr M, Prasanth KV. SRSF1 regulates the assembly of pre-mRNA processing factors in nuclear speckles. Molecular Biology of the Cell. 23: 3694-706. PMID 22855529 DOI: 10.1091/mbc.E12-03-0206  1
2012 Zhou Z, Qiu J, Liu W, Zhou Y, Plocinik RM, Li H, Hu Q, Ghosh G, Adams JA, Rosenfeld MG, Fu XD. The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus. Molecular Cell. 47: 422-33. PMID 22727668 DOI: 10.1016/j.molcel.2012.05.014  1
2012 Li H, Qiu J, Fu XD. RASL-seq for massively parallel and quantitative analysis of gene expression. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 4.13.1-9. PMID 22470064 DOI: 10.1002/0471142727.mb0413s98  0.8
2012 Chow ML, Pramparo T, Winn ME, Barnes CC, Li HR, Weiss L, Fan JB, Murray S, April C, Belinson H, Fu XD, Wynshaw-Boris A, Schork NJ, Courchesne E. Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages. Plos Genetics. 8: e1002592. PMID 22457638 DOI: 10.1371/journal.pgen.1002592  1
2012 Li H, Zhou H, Wang D, Qiu J, Zhou Y, Li X, Rosenfeld MG, Ding S, Fu XD. Versatile pathway-centric approach based on high-throughput sequencing to anticancer drug discovery. Proceedings of the National Academy of Sciences of the United States of America. 109: 4609-14. PMID 22396588 DOI: 10.1073/pnas.1200305109  1
2012 Chow ML, Winn ME, Li HR, April C, Wynshaw-Boris A, Fan JB, Fu XD, Courchesne E, Schork NJ. Preprocessing and Quality Control Strategies for Illumina DASL Assay-Based Brain Gene Expression Studies with Semi-Degraded Samples. Frontiers in Genetics. 3: 11. PMID 22375143 DOI: 10.3389/fgene.2012.00011  1
2012 Ji X, Fu XD. The mediator couples transcription and splicing. Molecular Cell. 45: 433-4. PMID 22365824 DOI: 10.1016/j.molcel.2012.02.003  0.72
2012 Xiao R, Tang P, Yang B, Huang J, Zhou Y, Shao C, Li H, Sun H, Zhang Y, Fu XD. Nuclear matrix factor hnRNP U/SAF-A exerts a global control of alternative splicing by regulating U2 snRNP maturation. Molecular Cell. 45: 656-68. PMID 22325991 DOI: 10.1016/j.molcel.2012.01.009  1
2012 Xu J. Technological innovation, productivity and competitiveness: Evidence from China’s it manufacturing sector China's Role in Global Economic Recovery. 253-271. DOI: 10.4324/9780203803257  0.68
2011 Chow ML, Li HR, Winn ME, April C, Barnes CC, Wynshaw-Boris A, Fan JB, Fu XD, Courchesne E, Schork NJ. Genome-wide expression assay comparison across frozen and fixed postmortem brain tissue samples. Bmc Genomics. 12: 449. PMID 21906392 DOI: 10.1186/1471-2164-12-449  1
2011 Gao XH, Xiao SL, Yao QF, Wang YJ, Fu XD. An updated GA signaling 'relief of repression' regulatory model. Molecular Plant. 4: 601-6. PMID 21690205 DOI: 10.1093/mp/ssr046  0.84
2011 Plocinik RM, Li S, Liu T, Hailey KL, Whitesides J, Whitehouse J, Ma CT, Fu XD, Gosh G, Woods VL, Jennings PA, Adams JA. Regulating SR protein phosphorylation through regions outside the kinase domain of SRPK1. Journal of Molecular Biology. 410: 131-45. PMID 21600902 DOI: 10.1016/j.jmb.2011.04.077  1
2011 Wang D, Garcia-Bassets I, Benner C, Li W, Su X, Zhou Y, Qiu J, Liu W, Kaikkonen MU, Ohgi KA, Glass CK, Rosenfeld MG, Fu XD. Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA. Nature. 474: 390-4. PMID 21572438 DOI: 10.1038/nature10006  1
2011 Cho S, Hoang A, Sinha R, Zhong XY, Fu XD, Krainer AR, Ghosh G. Interaction between the RNA binding domains of Ser-Arg splicing factor 1 and U1-70K snRNP protein determines early spliceosome assembly. Proceedings of the National Academy of Sciences of the United States of America. 108: 8233-8. PMID 21536904 DOI: 10.1073/pnas.1017700108  1
2011 Fox-Walsh K, Davis-Turak J, Zhou Y, Li H, Fu XD. A multiplex RNA-seq strategy to profile poly(A+) RNA: application to analysis of transcription response and 3' end formation. Genomics. 98: 266-71. PMID 21515359 DOI: 10.1016/j.ygeno.2011.04.003  1
2011 Han J, Xiong J, Wang D, Fu XD. Pre-mRNA splicing: where and when in the nucleus. Trends in Cell Biology. 21: 336-43. PMID 21514162 DOI: 10.1016/j.tcb.2011.03.003  0.8
2011 Ahn EY, DeKelver RC, Lo MC, Nguyen TA, Matsuura S, Boyapati A, Pandit S, Fu XD, Zhang DE. SON controls cell-cycle progression by coordinated regulation of RNA splicing. Molecular Cell. 42: 185-98. PMID 21504830 DOI: 10.1016/j.molcel.2011.03.014  0.8
2011 Huang C, Xie MH, Liu W, Yang B, Yang F, Huang J, Huang J, Wu Q, Fu XD, Zhang Y. A structured RNA in hepatitis B virus post-transcriptional regulatory element represses alternative splicing in a sequence-independent and position-dependent manner. The Febs Journal. 278: 1533-46. PMID 21371260 DOI: 10.1111/j.1742-4658.2011.08077.x  0.76
2011 Lovci MT, Li HR, Fu XD, Yeo GW. RNA-seq analysis of gene expression and alternative splicing by double-random priming strategy. Methods in Molecular Biology (Clifton, N.J.). 729: 247-55. PMID 21365495 DOI: 10.1007/978-1-61779-065-2_16  1
2011 Harismendy O, Notani D, Song X, Rahim NG, Tanasa B, Heintzman N, Ren B, Fu XD, Topol EJ, Rosenfeld MG, Frazer KA. 9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response. Nature. 470: 264-8. PMID 21307941 DOI: 10.1038/nature09753  1
2011 Wang W, Barnaby JY, Tada Y, Li H, Tör M, Caldelari D, Lee DU, Fu XD, Dong X. Timing of plant immune responses by a central circadian regulator. Nature. 470: 110-4. PMID 21293378 DOI: 10.1038/nature09766  0.8
2011 Han J, Ding JH, Byeon CW, Kim JH, Hertel KJ, Jeong S, Fu XD. SR proteins induce alternative exon skipping through their activities on the flanking constitutive exons. Molecular and Cellular Biology. 31: 793-802. PMID 21135118 DOI: 10.1128/MCB.01117-10  1
2010 Liu W, Zhou Y, Hu Z, Sun T, Denise A, Fu XD, Zhang Y. Regulation of splicing enhancer activities by RNA secondary structures. Febs Letters. 584: 4401-7. PMID 20888818 DOI: 10.1016/j.febslet.2010.09.039  1
2010 Ma CT, Ghosh G, Fu XD, Adams JA. Mechanism of dephosphorylation of the SR protein ASF/SF2 by protein phosphatase 1. Journal of Molecular Biology. 403: 386-404. PMID 20826166 DOI: 10.1016/j.jmb.2010.08.024  1
2010 Fox-Walsh K, Fu XD. Chromatin: the final frontier in splicing regulation? Developmental Cell. 18: 336-8. PMID 20230741 DOI: 10.1016/j.devcel.2010.03.002  0.56
2009 Xue Y, Zhou Y, Wu T, Zhu T, Ji X, Kwon YS, Zhang C, Yeo G, Black DL, Sun H, Fu XD, Zhang Y. Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping. Molecular Cell. 36: 996-1006. PMID 20064465 DOI: 10.1016/j.molcel.2009.12.003  1
2009 Lin C, Yang L, Tanasa B, Hutt K, Ju BG, Ohgi K, Zhang J, Rose DW, Fu XD, Glass CK, Rosenfeld MG. Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer. Cell. 139: 1069-83. PMID 19962179 DOI: 10.1016/j.cell.2009.11.030  1
2009 Wang D, Fu XD. DNA interaction networks: an information highway for regulated gene expression in the 3-dimentional space of the nucleus. Cell Research. 19: 1316-9. PMID 19956184 DOI: 10.1038/cr.2009.133  0.8
2009 Wang F, Fu XD, Zhou Y, Zhang Y. Down-regulation of the cyclin E1 oncogene expression by microRNA-16-1 induces cell cycle arrest in human cancer cells. Bmb Reports. 42: 725-30. PMID 19944013  1
2009 Nunez E, Fu XD, Rosenfeld MG. Nuclear organization in the 3D space of the nucleus - cause or consequence? Current Opinion in Genetics & Development. 19: 424-36. PMID 19846290 DOI: 10.1016/j.gde.2009.07.005  1
2009 Zhong XY, Wang P, Han J, Rosenfeld MG, Fu XD. SR proteins in vertical integration of gene expression from transcription to RNA processing to translation. Molecular Cell. 35: 1-10. PMID 19595711 DOI: 10.1016/j.molcel.2009.06.016  1
2009 Ma CT, Hagopian JC, Ghosh G, Fu XD, Adams JA. Regiospecific phosphorylation control of the SR protein ASF/SF2 by SRPK1. Journal of Molecular Biology. 390: 618-34. PMID 19477182 DOI: 10.1016/j.jmb.2009.05.060  1
2009 Zhong XY, Ding JH, Adams JA, Ghosh G, Fu XD. Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones. Genes & Development. 23: 482-95. PMID 19240134 DOI: 10.1101/gad.1752109  1
2009 Yeo GW, Coufal NG, Liang TY, Peng GE, Fu XD, Gage FH. An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells. Nature Structural & Molecular Biology. 16: 130-7. PMID 19136955 DOI: 10.1038/nsmb.1545  1
2008 Li H, Lovci MT, Kwon YS, Rosenfeld MG, Fu XD, Yeo GW. Determination of tag density required for digital transcriptome analysis: application to an androgen-sensitive prostate cancer model. Proceedings of the National Academy of Sciences of the United States of America. 105: 20179-84. PMID 19088194 DOI: 10.1073/pnas.0807121105  1
2008 Hu Q, Kwon YS, Nunez E, Cardamone MD, Hutt KR, Ohgi KA, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG, Fu XD. Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules. Proceedings of the National Academy of Sciences of the United States of America. 105: 19199-204. PMID 19052240 DOI: 10.1073/pnas.0810634105  1
2008 Gao XH, Huang XZ, Xiao SL, Fu XD. Evolutionarily conserved DELLA-mediated gibberellin signaling in plants. Journal of Integrative Plant Biology. 50: 825-34. PMID 18713393 DOI: 10.1111/j.1744-7909.2008.00703.x  0.84
2008 Hagopian JC, Ma CT, Meade BR, Albuquerque CP, Ngo JC, Ghosh G, Jennings PA, Fu XD, Adams JA. Adaptable molecular interactions guide phosphorylation of the SR protein ASF/SF2 by SRPK1. Journal of Molecular Biology. 382: 894-909. PMID 18687337 DOI: 10.1016/j.jmb.2008.07.055  1
2008 Lin S, Coutinho-Mansfield G, Wang D, Pandit S, Fu XD. The splicing factor SC35 has an active role in transcriptional elongation. Nature Structural & Molecular Biology. 15: 819-26. PMID 18641664 DOI: 10.1038/nsmb.1461  1
2008 Nunez E, Kwon YS, Hutt KR, Hu Q, Cardamone MD, Ohgi KA, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG, Fu XD. Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules. Cell. 134: 189. PMID 18630350 DOI: 10.1016/j.cell.2008.06.045  1
2008 Pandit S, Wang D, Fu XD. Functional integration of transcriptional and RNA processing machineries. Current Opinion in Cell Biology. 20: 260-5. PMID 18436438 DOI: 10.1016/j.ceb.2008.03.001  0.8
2008 Nunez E, Kwon YS, Hutt KR, Hu Q, Cardamone MD, Ohgi KA, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG, Fu XD. Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules. Cell. 132: 996-1010. PMID 18358812 DOI: 10.1016/j.cell.2008.01.051  1
2008 Ngo JC, Giang K, Chakrabarti S, Ma CT, Huynh N, Hagopian JC, Dorrestein PC, Fu XD, Adams JA, Ghosh G. A sliding docking interaction is essential for sequential and processive phosphorylation of an SR protein by SRPK1. Molecular Cell. 29: 563-76. PMID 18342604 DOI: 10.1016/j.molcel.2007.12.017  1
2008 Ma CT, Velazquez-Dones A, Hagopian JC, Ghosh G, Fu XD, Adams JA. Ordered multi-site phosphorylation of the splicing factor ASF/SF2 by SRPK1. Journal of Molecular Biology. 376: 55-68. PMID 18155240 DOI: 10.1016/j.jmb.2007.08.029  1
2007 Lin S, Fu XD. SR proteins and related factors in alternative splicing. Advances in Experimental Medicine and Biology. 623: 107-22. PMID 18380343  1
2007 Coutinho-Mansfield GC, Xue Y, Zhang Y, Fu XD. PTB/nPTB switch: a post-transcriptional mechanism for programming neuronal differentiation. Genes & Development. 21: 1573-7. PMID 17606635 DOI: 10.1101/gad.1575607  0.76
2007 Xiao R, Sun Y, Ding JH, Lin S, Rose DW, Rosenfeld MG, Fu XD, Li X. Splicing regulator SC35 is essential for genomic stability and cell proliferation during mammalian organogenesis. Molecular and Cellular Biology. 27: 5393-402. PMID 17526736 DOI: 10.1128/MCB.00288-07  1
2007 Lukasiewicz R, Velazquez-Dones A, Huynh N, Hagopian J, Fu XD, Adams J, Ghosh G. Structurally unique yeast and mammalian serine-arginine protein kinases catalyze evolutionarily conserved phosphorylation reactions. The Journal of Biological Chemistry. 282: 23036-43. PMID 17517895 DOI: 10.1074/jbc.M611305200  1
2007 Wang J, Scully K, Zhu X, Cai L, Zhang J, Prefontaine GG, Krones A, Ohgi KA, Zhu P, Garcia-Bassets I, Liu F, Taylor H, Lozach J, Jayes FL, Korach KS, ... ... Fu XD, et al. Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature. 446: 882-7. PMID 17392792 DOI: 10.1038/nature05671  1
2007 Kwon YS, Garcia-Bassets I, Hutt KR, Cheng CS, Jin M, Liu D, Benner C, Wang D, Ye Z, Bibikova M, Fan JB, Duan L, Glass CK, Rosenfeld MG, Fu XD. Sensitive ChIP-DSL technology reveals an extensive estrogen receptor alpha-binding program on human gene promoters. Proceedings of the National Academy of Sciences of the United States of America. 104: 4852-7. PMID 17360330 DOI: 10.1073/pnas.0700715104  1
2007 Hu A, Fu XD. Splicing oncogenes. Nature Structural & Molecular Biology. 14: 174-5. PMID 17334403 DOI: 10.1038/nsmb0307-174  0.68
2007 Garcia-Bassets I, Kwon YS, Telese F, Prefontaine GG, Hutt KR, Cheng CS, Ju BG, Ohgi KA, Wang J, Escoubet-Lozach L, Rose DW, Glass CK, Fu XD, Rosenfeld MG. Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors. Cell. 128: 505-18. PMID 17289570 DOI: 10.1016/j.cell.2006.12.038  1
2007 Ngo JC, Gullingsrud J, Giang K, Yeh MJ, Fu XD, Adams JA, McCammon JA, Ghosh G. SR protein kinase 1 is resilient to inactivation. Structure (London, England : 1993). 15: 123-33. PMID 17223538 DOI: 10.1016/j.str.2006.11.011  1
2006 Wang HS, Chen XC, Li MZ, Zhang W, Deng QY, Fu XD, Zhang HM, Wang H, Zhou BP. [Study on specific cellular immunity of enhance intracellular survival antigen of Mycobacterium tuberculosis in patients with pulmonary tuberculosis]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue = Chinese Critical Care Medicine = Zhongguo Weizhongbing Jijiuyixue. 18: 498-500. PMID 16887067  0.8
2006 Li HR, Wang-Rodriguez J, Nair TM, Yeakley JM, Kwon YS, Bibikova M, Zheng C, Zhou L, Zhang K, Downs T, Fu XD, Fan JB. Two-dimensional transcriptome profiling: identification of messenger RNA isoform signatures in prostate cancer from archived paraffin-embedded cancer specimens. Cancer Research. 66: 4079-88. PMID 16618727 DOI: 10.1158/0008-5472.CAN-05-4264  0.72
2006 Zhang C, Li HR, Fan JB, Wang-Rodriguez J, Downs T, Fu XD, Zhang MQ. Profiling alternatively spliced mRNA isoforms for prostate cancer classification. Bmc Bioinformatics. 7: 202. PMID 16608523 DOI: 10.1186/1471-2105-7-202  0.72
2006 Ding JH, Zhong XY, Hagopian JC, Cruz MM, Ghosh G, Feramisco J, Adams JA, Fu XD. Regulated cellular partitioning of SR protein-specific kinases in mammalian cells. Molecular Biology of the Cell. 17: 876-85. PMID 16319169 DOI: 10.1091/mbc.E05-10-0963  1
2005 Xu X, Fu XD. Conditional knockout mice to study alternative splicing in vivo. Methods (San Diego, Calif.). 37: 387-92. PMID 16314268 DOI: 10.1016/j.ymeth.2005.07.019  1
2005 Lin S, Xiao R, Sun P, Xu X, Fu XD. Dephosphorylation-dependent sorting of SR splicing factors during mRNP maturation. Molecular Cell. 20: 413-25. PMID 16285923 DOI: 10.1016/j.molcel.2005.09.015  1
2005 Zheng CL, Fu XD, Gribskov M. Characteristics and regulatory elements defining constitutive splicing and different modes of alternative splicing in human and mouse. Rna (New York, N.Y.). 11: 1777-87. PMID 16251388 DOI: 10.1261/rna.2660805  0.64
2005 Zheng CL, Kwon YS, Li HR, Zhang K, Coutinho-Mansfield G, Yang C, Nair TM, Gribskov M, Fu XD. MAASE: an alternative splicing database designed for supporting splicing microarray applications. Rna (New York, N.Y.). 11: 1767-76. PMID 16251387 DOI: 10.1261/rna.2650905  0.8
2005 Velazquez-Dones A, Hagopian JC, Ma CT, Zhong XY, Zhou H, Ghosh G, Fu XD, Adams JA. Mass spectrometric and kinetic analysis of ASF/SF2 phosphorylation by SRPK1 and Clk/Sty. The Journal of Biological Chemistry. 280: 41761-8. PMID 16223727 DOI: 10.1074/jbc.M504156200  1
2005 Ngo JC, Chakrabarti S, Ding JH, Velazquez-Dones A, Nolen B, Aubol BE, Adams JA, Fu XD, Ghosh G. Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2. Molecular Cell. 20: 77-89. PMID 16209947 DOI: 10.1016/j.molcel.2005.08.025  1
2005 Zheng Y, Fu XD, Ou JH. Suppression of hepatitis B virus replication by SRPK1 and SRPK2 via a pathway independent of the phosphorylation of the viral core protein. Virology. 342: 150-8. PMID 16122776 DOI: 10.1016/j.virol.2005.07.030  0.56
2005 Xu X, Yang D, Ding JH, Wang W, Chu PH, Dalton ND, Wang HY, Bermingham JR, Ye Z, Liu F, Rosenfeld MG, Manley JL, Ross J, Chen J, Xiao RP, ... ... Fu XD, et al. ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle. Cell. 120: 59-72. PMID 15652482 DOI: 10.1016/j.cell.2004.11.036  1
2004 Fan JB, Yeakley JM, Bibikova M, Chudin E, Wickham E, Chen J, Doucet D, Rigault P, Zhang B, Shen R, McBride C, Li HR, Fu XD, Oliphant A, Barker DL, et al. A versatile assay for high-throughput gene expression profiling on universal array matrices. Genome Research. 14: 878-85. PMID 15123585 DOI: 10.1101/gr.2167504  1
2004 Zheng CL, Nair TM, Gribskov M, Kwon YS, Li HR, Fu XD. A database designed to computationally aid an experimental approach to alternative splicing. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 78-88. PMID 14992494  0.64
2004 Ding JH, Xu X, Yang D, Chu PH, Dalton ND, Ye Z, Yeakley JM, Cheng H, Xiao RP, Ross J, Chen J, Fu XD. Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart. The Embo Journal. 23: 885-96. PMID 14963485 DOI: 10.1038/sj.emboj.7600054  1
2003 Aubol BE, Chakrabarti S, Ngo J, Shaffer J, Nolen B, Fu XD, Ghosh G, Adams JA. Processive phosphorylation of alternative splicing factor/splicing factor 2. Proceedings of the National Academy of Sciences of the United States of America. 100: 12601-6. PMID 14555757 DOI: 10.1073/pnas.1635129100  1
2003 Yun CY, Velazquez-Dones AL, Lyman SK, Fu XD. Phosphorylation-dependent and -independent nuclear import of RS domain-containing splicing factors and regulators. The Journal of Biological Chemistry. 278: 18050-5. PMID 12637531 DOI: 10.1074/jbc.M211714200  0.96
2002 Yeakley JM, Fan JB, Doucet D, Luo L, Wickham E, Ye Z, Chee MS, Fu XD. Profiling alternative splicing on fiber-optic arrays. Nature Biotechnology. 20: 353-8. PMID 11923840 DOI: 10.1038/nbt0402-353  0.64
2001 Wang HY, Xu X, Ding JH, Bermingham JR, Fu XD. SC35 plays a role in T cell development and alternative splicing of CD45. Molecular Cell. 7: 331-42. PMID 11239462 DOI: 10.1016/S1097-2765(01)00181-2  1
2001 Nolen B, Yun CY, Wong CF, McCammon JA, Fu XD, Ghosh G. The structure of Sky1p reveals a novel mechanism for constitutive activity. Nature Structural Biology. 8: 176-83. PMID 11175909 DOI: 10.1038/84178  1
2000 Yun CY, Fu XD. Conserved SR protein kinase functions in nuclear import and its action is counteracted by arginine methylation in Saccharomyces cerevisiae. The Journal of Cell Biology. 150: 707-18. PMID 10952997  0.96
1999 Yeakley JM, Tronchère H, Olesen J, Dyck JA, Wang HY, Fu XD. Phosphorylation regulates in vivo interaction and molecular targeting of serine/arginine-rich pre-mRNA splicing factors. The Journal of Cell Biology. 145: 447-55. PMID 10225947  0.88
1999 Wang HY, Arden KC, Bermingham JR, Viars CS, Lin W, Boyer AD, Fu XD. Localization of serine kinases, SRPK1 (SFRSK1) and SRPK2 (SFRSK2), specific for the SR family of splicing factors in mouse and human chromosomes. Genomics. 57: 310-5. PMID 10198174 DOI: 10.1006/geno.1999.5770  1
1998 Wang HY, Lin W, Dyck JA, Yeakley JM, Songyang Z, Cantley LC, Fu XD. SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells. The Journal of Cell Biology. 140: 737-50. PMID 9472028  0.88
1995 Fu XD. The superfamily of arginine/serine-rich splicing factors Rna (New York, N.Y.). 1: 663-680. PMID 7585252  1
1994 Gui JF, Lane WS, Fu XD. A serine kinase regulates intracellular localization of splicing factors in the cell cycle. Nature. 369: 678-82. PMID 8208298 DOI: 10.1038/369678a0  0.36
1993 Fu XD. Specific commitment of different pre-mRNAs to splicing by single SR proteins Nature. 365: 82-85. PMID 8361546 DOI: 10.1038/365082a0  1
1992 Fu XD, Maniatis T. The 35-kDa mammalian splicing factor SC35 mediates specific interactions between U1 and U2 small nuclear ribonucleoprotein particles at the 3' splice site Proceedings of the National Academy of Sciences of the United States of America. 89: 1725-1729. PMID 1531875  1
1992 Fu XD, Mayeda A, Maniatis T, Krainer AR. General splicing factors SF2 and SC35 have equivalent activities in vitro, and both affect alternative 5' and 3' splice site selection. Proceedings of the National Academy of Sciences of the United States of America. 89: 11224-8. PMID 1454802  1
1992 Fu XD, Maniatis T. Isolation of a complementary DNA that encodes the mammalian splicing factor SC35 Science. 256: 535-538. PMID 1373910  1
1991 Fu XD, Katz RA, Skalka AM, Maniatis T. The role of branchpoint and 3'-exon sequences in the control of balanced splicing of avian retrovirus RNA. Genes & Development. 5: 211-20. PMID 1847346  1
1991 Spector DL, Fu XD, Maniatis T. Associations between distinct pre-mRNA splicing components and the cell nucleus Embo Journal. 10: 3467-3481. PMID 1833187  1
1990 Fu XD, Maniatis T. Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus. Nature. 343: 437-41. PMID 2137203 DOI: 10.1038/343437a0  1
1989 Leis J, Phillips N, Fu X, Tuazon PT, Traugh JA. Phosphorylation of avian retrovirus matrix protein by Ca2+/phospholipid-dependent protein kinase. European Journal of Biochemistry / Febs. 179: 415-22. PMID 2537209  1
1988 Jentoft JE, Smith LM, Fu XD, Johnson M, Leis J. Conserved cysteine and histidine residues of the avian myeloblastosis virus nucleocapsid protein are essential for viral replication but are not "zinc-binding fingers". Proceedings of the National Academy of Sciences of the United States of America. 85: 7094-8. PMID 2845395 DOI: 10.1073/pnas.85.19.7094  1
1988 Fu X, Katz RA, Skalka AM, Leis J. Site-directed mutagenesis of the avian retrovirus nucleocapsid protein, pp12. Mutation which affects RNA binding in vitro blocks viral replication Journal of Biological Chemistry. 263: 2140-2145. PMID 2828360  1
1988 Fu XD, Tuazon PT, Traugh JA, Leis J. Site-directed mutagenesis of the avian retrovirus nucleocapsid protein, pp 12, at Serine 40, the primary site of phosphorylation in vivo. The Journal of Biological Chemistry. 263: 2134-9. PMID 2448305  1
1986 Katz RA, Fu XD, Skalka AM, Leis J. Avian retrovirus nucleocapsid protein, pp12, produced in Escherichia coli has biochemical properties identical to unphosphorylated viral protein Gene. 50: 361-369. PMID 2438190 DOI: 10.1016/0378-1119(86)90340-9  1
1985 Fu X, Phillips N, Jentoft J, Tuazon PT, Traugh JA, Leis J. Site-specific phosphorylation of avian retrovirus nucleocapsid protein pp12 regulates binding to viral RNA. Evidence for different protein conformations. The Journal of Biological Chemistry. 260: 9941-7. PMID 2991270  1
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