John J. Kopchick - Publications

Affiliations: 
Ohio University, Athens, OH, United States 
Area:
Molecular Biology, Medicine and Surgery, Biochemistry

372 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 List EO, Berryman DE, Basu R, Buchman M, Funk K, Kulkarni P, Duran-Ortiz S, Qian Y, Jensen EA, Young JA, Yildirim G, Yakar S, Kopchick JJ. The effects of 20-kDa human placental GH in male and female GH deficient mice: an improved human GH? Endocrinology. PMID 32556100 DOI: 10.1210/endocr/bqaa097  0.88
2020 Young JA, Henry BE, Benencia F, Bell S, List EO, Kopchick JJ, Berryman DE. GHR Mice are protected from obesity-related white adipose tissue inflammation. Journal of Neuroendocrinology. e12854. PMID 32350959 DOI: 10.1111/jne.12854  0.88
2020 Wasinski F, Pedroso JAB, Dos Santos WO, Furigo IC, Garcia-Galiano D, Elias CF, List EO, Kopchick JJ, Szawka RE, Donato J. Tyrosine hydroxylase neurons regulate growth hormone secretion via short-loop negative feedback. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32317389 DOI: 10.1523/JNEUROSCI.2531-19.2020  0.84
2020 Wasinski F, Furigo IC, Teixeira PDS, Ramos-Lobo AM, Peroni CN, Bartolini P, List EO, Kopchick JJ, Donato J. Growth Hormone Receptor Deletion Reduces the Density of Axonal Projections from Hypothalamic Arcuate Nucleus Neurons. Neuroscience. PMID 32229232 DOI: 10.1016/j.neuroscience.2020.03.037  0.84
2020 Jensen EA, Young JA, Jackson Z, Busken J, List EO, Carroll RK, Kopchick JJ, Murphy ER, Berryman DE. Growth hormone deficiency and excess alter the gut microbiome in adult male mice. Endocrinology. PMID 32100023 DOI: 10.1210/endocr/bqaa026  0.88
2020 Høyer KL, Høgild ML, List EO, Lee KY, Kissinger E, Sharma R, Erik Magnusson N, Puri V, Kopchick JJ, Jørgensen JOL, Jessen N. The acute effects of growth hormone in adipose tissue is associated with suppression of antilipolytic signals. Physiological Reports. 8: e14373. PMID 32073221 DOI: 10.14814/phy2.14373  0.84
2019 Basu R, Kopchick JJ. The effects of growth hormone on therapy resistance in cancer. Cancer Drug Resistance (Alhambra, Calif.). 2: 827-846. PMID 32382711 DOI: 10.20517/cdr.2019.27  0.56
2019 List EO, Berryman DE, Jensen EA, Kulkarni P, McKenna S, Kopchick JJ. New insights of growth hormone (GH) actions from tissue-specific GH receptor knockouts in mice. Archives of Endocrinology and Metabolism. 63: 557-567. PMID 31939480 DOI: 10.20945/2359-3997000000185  0.88
2019 Duran-Ortiz S, Noboa V, Kopchick JJ. Tissue-specific disruption of the growth hormone receptor (GHR) in mice: An update. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 51: 1-5. PMID 31923746 DOI: 10.1016/j.ghir.2019.12.004  0.76
2019 Kopchick JJ, Berryman DE, Puri V, Lee KY, Jorgensen JOL. The effects of growth hormone on adipose tissue: old observations, new mechanisms. Nature Reviews. Endocrinology. PMID 31780780 DOI: 10.1038/s41574-019-0280-9  0.88
2019 Isola JVV, Zanini BM, Sidhom S, Kopchick JJ, Bartke A, Masternak MM, Stout MB, Schneider A. 17α-Estradiol promotes ovarian aging in growth hormone receptor knockout mice, but not wild-type littermates. Experimental Gerontology. 129: 110769. PMID 31698046 DOI: 10.1016/j.exger.2019.110769  0.56
2019 Basu R, Kulkarni P, Qian Y, Walsh C, Arora P, Davis E, Duran-Ortiz S, Funk K, Ibarra D, Kruse C, Mathes S, McHugh T, Brittain A, Berryman DE, List EO, ... ... Kopchick JJ, et al. Growth Hormone Upregulates Melanocyte-Inducing Transcription Factor Expression and Activity via JAK2-STAT5 and SRC Signaling in GH Receptor-Positive Human Melanoma. Cancers. 11. PMID 31547367 DOI: 10.3390/cancers11091352  0.88
2019 Quaresma PGF, Teixeira PDS, Furigo IC, Wasinski F, Couto GC, Frazão R, List EO, Kopchick JJ, Donato J. Growth hormone/STAT5 signaling in proopiomelanocortin neurons regulates glucoprivic hyperphagia. Molecular and Cellular Endocrinology. 498: 110574. PMID 31494175 DOI: 10.1016/j.mce.2019.110574  0.84
2019 Teixeira PDS, Couto GC, Furigo IC, List EO, Kopchick JJ, Donato J. Central growth hormone action regulates metabolism during pregnancy. American Journal of Physiology. Endocrinology and Metabolism. PMID 31479305 DOI: 10.1152/ajpendo.00229.2019  0.84
2019 Bohlen TM, Zampieri TT, Furigo IC, Teixeira PD, List EO, Kopchick J, Donato J, Frazao R. Central growth hormone signaling is not required for the timing of puberty. The Journal of Endocrinology. PMID 31470413 DOI: 10.1530/JOE-19-0242  0.84
2019 Furigo IC, de Souza GO, Teixeira PDS, Guadagnini D, Frazão R, List EO, Kopchick JJ, Prada PO, Donato J. Growth hormone enhances the recovery of hypoglycemia ventromedial hypothalamic neurons. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201901315R. PMID 31366244 DOI: 10.1096/fj.201901315R  0.84
2019 Brittain AL, Kopchick JJ. A review of renal GH/IGF1 family gene expression in chronic kidney diseases. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 48: 1-4. PMID 31352157 DOI: 10.1016/j.ghir.2019.07.001  0.56
2019 Swindell WR, Kruse CPS, List EO, Berryman DE, Kopchick JJ. ALS blood expression profiling identifies new biomarkers, patient subgroups, and evidence for neutrophilia and hypoxia. Journal of Translational Medicine. 17: 170. PMID 31118040 DOI: 10.1186/s12967-019-1909-0  0.88
2019 List EO, Berryman DE, Buchman M, Jensen EA, Funk K, Duran-Ortiz S, Qian Y, Young JA, Slyby J, McKenna S, Kopchick JJ. GH "knockout" mice have increased subcutaneous adipose tissue with decreased fibrosis and enhanced insulin sensitivity. Endocrinology. PMID 31099824 DOI: 10.1210/en.2019-00167  0.88
2019 Young JA, Jensen EA, Stevens A, Duran-Ortiz S, List EO, Berryman DE, Kopchick JJ. Characterization of an intestine-specific GH receptor knockout (IntGHRKO) mouse. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 46: 5-15. PMID 31078722 DOI: 10.1016/j.ghir.2019.05.001  0.88
2019 Kruse CPS, Cottrill DA, Kopchick JJ. Could calgranulins and advanced glycated end products potentiate acromegaly pathophysiology? Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 46: 1-4. PMID 31071497 DOI: 10.1016/j.ghir.2019.04.002  0.32
2019 Furigo IC, Teixeira PDS, de Souza GO, Couto GCL, Romero GG, Perelló M, Frazão R, Elias LL, Metzger M, List EO, Kopchick JJ, Donato J. Author Correction: Growth hormone regulates neuroendocrine responses to weight loss via AgRP neurons. Nature Communications. 10: 980. PMID 30804339 DOI: 10.1038/s41467-019-09022-2  0.84
2019 Furigo IC, Teixeira PDS, de Souza GO, Couto GCL, Romero GG, Perelló M, Frazão R, Elias LL, Metzger M, List EO, Kopchick JJ, J D. Growth hormone regulates neuroendocrine responses to weight loss via AgRP neurons. Nature Communications. 10: 662. PMID 30737388 DOI: 10.1038/s41467-019-08607-1  0.84
2018 List EO, Berryman DE, Buchman M, Parker C, Funk K, Bell S, Duran-Ortiz S, Qian Y, Young JA, Wilson C, Slyby J, McKenna S, Jensen EA, Kopchick JJ. Adipocyte-specific GH receptor null (AdGHRKO) mice have enhanced insulin sensitivity with reduced liver triglycerides. Endocrinology. PMID 30462209 DOI: 10.1210/en.2018-00850  0.88
2018 Sharma R, Luong Q, Sharma VM, Harberson M, Harper B, Colborn A, Berryman DE, Jessen N, Jørgensen JOL, Kopchick JJ, Puri V, Lee KY. Growth hormone controls lipolysis by regulation of FSP27 expression. The Journal of Endocrinology. 239: 289-301. PMID 30400015 DOI: 10.1530/JOE-18-0282  0.88
2018 Buchman M, Bell S, Kopchick JJ. Growth Hormone Discovery and Structure. Pediatric Endocrinology Reviews : Per. 16: 2-10. PMID 30378777 DOI: 10.17458/per.vol16.2018.bbk.ghdiscoverystructure  0.36
2018 Liu Z, Solesio ME, Schaffler MB, Frikha-Benayed D, Rosen CJ, Werner H, Kopchick JJ, Pavlov EV, Abramov AY, Yakar S. Mitochondrial Function Is Compromised in Cortical Bone Osteocytes of Long-Lived Growth Hormone Receptor Null Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 30216544 DOI: 10.1002/jbmr.3573  0.36
2018 Duran-Ortiz S, Bell S, Kopchick JJ. Standardizing protocols dealing with growth hormone receptor gene disruption in mice using the Cre-lox system. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 42: 52-57. PMID 30195091 DOI: 10.1016/j.ghir.2018.08.003  0.76
2018 Nelson CN, List EO, Ieremia M, Constantin L, Chhabra Y, Kopchick JJ, Waters MJ. Growth hormone activated STAT5 is required for induction of beige fat in vivo. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 42: 40-51. PMID 30193158 DOI: 10.1016/j.ghir.2018.08.004  0.84
2018 Swindell WR, List EO, Berryman DE, Kopchick JJ. Transcriptional profiling identifies strain-specific effects of caloric restriction and opposite responses in human and mouse white adipose tissue. Aging. PMID 29708498 DOI: 10.18632/aging.101424  0.88
2018 Johannsson G, Bidlingmaier M, Biller B, Boguszewski M, Casanueva FF, Chanson P, Choong CS, Clayton PE, Clemmons D, Dattani M, Frystyk J, Ho KKY, Hoffman A, Horikawa R, Juul A, ... Kopchick J, et al. Growth Hormone Research Society perspective on biomarkers of GH action in children and adults. Endocrine Connections. PMID 29483159 DOI: 10.1530/EC-18-0047  0.36
2018 Basu R, Qian Y, Kopchick JJ. MECHANISMS IN ENDOCRINOLOGY: Lessons from growth hormone receptor gene disrupted mice: Are there benefits of endocrine defects? European Journal of Endocrinology. PMID 29459441 DOI: 10.1530/EJE-18-0018  0.76
2018 Hjortebjerg R, Berryman DE, Comisford R, List EO, Oxvig C, Bjerre M, Frystyk J, Kopchick JJ. Depot-specific and GH-dependent regulation of IGF binding protein-4, pregnancy-associated plasma protein-A, and stanniocalcin-2 in murine adipose tissue. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. PMID 29398370 DOI: 10.1016/j.ghir.2018.01.001  0.88
2018 Fang Y, Hill CM, Darcy J, Reyes-Ordoñez A, Arauz E, McFadden S, Zhang C, Osland J, Gao J, Zhang T, Frank SJ, Javors MA, Yuan R, Kopchick JJ, Sun LY, et al. Effects of rapamycin on growth hormone receptor knockout mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 29378959 DOI: 10.1073/pnas.1717065115  0.56
2017 Householder LA, Comisford R, Duran-Ortiz S, Lee K, Troike K, Wilson C, Jara A, Harberson M, List EO, Kopchick JJ, Berryman DE. Increased fibrosis: A novel means by which GH influences white adipose tissue function. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. PMID 29279183 DOI: 10.1016/j.ghir.2017.12.010  0.88
2017 Duran-Ortiz S, Noboa V, Kopchick JJ. Disruption of the GH receptor gene in adult mice and in insulin sensitive tissues. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. PMID 29198419 DOI: 10.1016/j.ghir.2017.11.003  0.76
2017 Brittain AL, Basu R, Qian Y, Kopchick JJ. Growth Hormone and the Epithelial-to-Mesenchymal Transition. The Journal of Clinical Endocrinology and Metabolism. PMID 28938477 DOI: 10.1210/jc.2017-01000  0.76
2017 Consitt LA, Saneda A, Saxena G, List EO, Kopchick JJ. Mice overexpressing growth hormone exhibit increased skeletal muscle myostatin and MuRF1 with attenuation of muscle mass. Skeletal Muscle. 7: 17. PMID 28870245 DOI: 10.1186/s13395-017-0133-y  0.84
2017 Duran-Ortiz S, Brittain AL, Kopchick JJ. The impact of growth hormone on proteomic profiles: a review of mouse and adult human studies. Clinical Proteomics. 14: 24. PMID 28670222 DOI: 10.1186/s12014-017-9160-2  0.76
2017 Troike KM, Henry BE, Jensen EA, Young JA, List EO, Kopchick JJ, Berryman DE. Impact of Growth Hormone on Regulation of Adipose Tissue. Comprehensive Physiology. 7: 819-840. PMID 28640444 DOI: 10.1002/cphy.c160027  0.88
2017 Hine C, Kim HJ, Zhu Y, Harputlugil E, Longchamp A, Matos MS, Ramadoss P, Bauerle K, Brace L, Asara JM, Ozaki CK, Cheng SY, Singha S, Ahn KH, Kimmelman A, ... ... Kopchick JJ, et al. Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production. Cell Metabolism. 25: 1320-1333.e5. PMID 28591635 DOI: 10.1016/j.cmet.2017.05.003  0.56
2017 Fang Y, McFadden S, Darcy J, Hill CM, Huber JA, Verhulst S, Kopchick JJ, Miller RA, Sun LY, Bartke A. Differential effects of early-life nutrient restriction in long-lived GHR-KO and normal mice. Geroscience. PMID 28523599 DOI: 10.1007/s11357-017-9978-6  0.56
2017 Soendergaard C, Young JA, Kopchick JJ. Growth Hormone Resistance-Special Focus on Inflammatory Bowel Disease. International Journal of Molecular Sciences. 18. PMID 28486400 DOI: 10.3390/ijms18051019  0.52
2017 Liu Z, Han T, Fishman S, Butler J, Zimmermann T, Tremblay F, Harbison C, Agrawal N, Kopchick JJ, Schaffler MB, Yakar S. Ablation of hepatic production of the acid labile subunit in the bovine-GH transgenic mice; effects on organ and skeletal growth. Endocrinology. PMID 28475811 DOI: 10.1210/en.2016-1952  0.36
2017 Cady G, Landeryou T, Garratt M, Kopchick JJ, Qi N, Garcia-Galiano D, Elias CF, Myers MG, Miller RA, Sandoval DA, Sadagurski M. Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neurons. Molecular Metabolism. 6: 393-405. PMID 28462074 DOI: 10.1016/j.molmet.2017.03.001  0.52
2017 Hjortebjerg R, Berryman DE, Comisford R, Frank SJ, List EO, Bjerre M, Frystyk J, Kopchick JJ. Insulin, IGF-1, and GH Receptors are Altered in an Adipose Tissue Depot-Specific Manner in Male Mice with Modified GH Action. Endocrinology. PMID 28323915 DOI: 10.1210/en.2017-00084  0.88
2017 Bennis MT, Schneider A, Victoria B, Do A, Wiesenborn DS, Spinel L, Gesing A, Kopchick JJ, Siddiqi SA, Masternak MM. The role of transplanted visceral fat from the long-lived growth hormone receptor knockout mice on insulin signaling. Geroscience. 39: 51-59. PMID 28299640 DOI: 10.1007/s11357-017-9957-y  0.44
2017 Basu R, Baumgaertel N, Wu S, Kopchick JJ. Growth Hormone Receptor Knockdown Sensitizes Human Melanoma Cells to Chemotherapy by Attenuating Expression of ABC Drug Efflux Pumps. Hormones & Cancer. PMID 28293855 DOI: 10.1007/s12672-017-0292-7  0.56
2017 Basu R, Wu S, Kopchick JJ. Targeting growth hormone receptor in human melanoma cells attenuates tumor progression and epithelial mesenchymal transition via suppression of multiple oncogenic pathways. Oncotarget. PMID 28223541 DOI: 10.18632/oncotarget.15375  0.56
2016 Berryman DE, Henry B, Hjortebjerg R, List EO, Kopchick JJ. Developments in our understanding of the effects of growth hormone on white adipose tissue from mice: implications to the clinic. Expert Review of Endocrinology & Metabolism. 11: 197-207. PMID 28435436 DOI: 10.1586/17446651.2016.1147950  0.88
2016 List EO, Jensen E, Kowalski J, Buchman M, Berryman DE, Kopchick JJ. Diet-induced weight loss is sufficient to reduce senescent cell number in white adipose tissue of weight-cycled mice. Nutrition and Healthy Aging. 4: 95-99. PMID 28035346 DOI: 10.3233/NHA-1614  0.88
2016 Junnila RK, Duran-Ortiz S, Suer O, Sustarsic EG, Berryman DE, List EO, Kopchick JJ. Disruption of the growth hormone receptor gene in adult mice increases maximal lifespan in females. Endocrinology. en20161649. PMID 27732088 DOI: 10.1210/en.2016-1649  0.88
2016 Gesing A, Wiesenborn D, Do A, Menon V, Schneider A, Victoria B, Stout MB, Kopchick JJ, Bartke A, Masternak MM. A Long-lived Mouse Lacking Both Growth Hormone and Growth Hormone Receptor: A New Animal Model for Aging Studies. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 27688483 DOI: 10.1093/gerona/glw193  0.56
2016 Brooks NE, Hjortebjerg R, Henry BE, List EO, Kopchick JJ, Berryman DE. Fibroblast growth factor 21, fibroblast growth factor receptor 1, and β-Klotho expression in bovine growth hormone transgenic and growth hormone receptor knockout mice. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 30: 22-30. PMID 27585733 DOI: 10.1016/j.ghir.2016.08.003  0.88
2016 Hascup KN, Lynn MK, Fitzgerald PJ, Randall S, Kopchick JJ, Boger HA, Bartke A, Hascup ER. Enhanced Cognition and Hypoglutamatergic Signaling in a Growth Hormone Receptor Knockout Mouse Model of Successful Aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 27208894 DOI: 10.1093/gerona/glw088  0.56
2016 Jara A, Liu X, Sim D, Benner CM, Duran-Ortiz S, Qian Y, List EO, Berryman DE, Kim JK, Kopchick JJ. Cardiac-specific disruption of GH receptor alters glucose homeostasis while maintaining normal cardiac performance in adult male mice. Endocrinology. en20151686. PMID 27035649 DOI: 10.1210/en.2015-1686  1
2016 Christiansen JS, Backeljauw P, Bidlingmaier M, Biller B, Boguszewski M, Casanueva FF, Chanson P, Chatelain P, Choong CS, Clemmons DR, Cohen L, Cohen P, Frystyk J, Grimberg A, Hasegawa Y, ... ... Kopchick JJ, et al. Growth Hormone Research Society Perspective on the Development of Long-Acting Growth Hormone Preparations. European Journal of Endocrinology / European Federation of Endocrine Societies. PMID 27009113 DOI: 10.1530/EJE-16-0111  1
2016 Liu Y, Knop E, Knop N, Sullivan DA, List EO, Kopchick JJ, Kam WR, Ding J. Growth Hormone Influence on the Morphology and Size of the Mouse Meibomian Gland. Journal of Ophthalmology. 2016: 5728071. PMID 26981277 DOI: 10.1155/2016/5728071  1
2016 Visser WE, Bombardieri CR, Zevenbergen C, Barnhoorn S, Ottaviani A, van der Pluijm I, Brandt R, Kaptein E, van Heerebeek R, van Toor H, Garinis GA, Peeters RP, Medici M, van Ham W, Vermeij WP, ... ... Kopchick JJ, et al. Tissue-Specific Suppression of Thyroid Hormone Signaling in Various Mouse Models of Aging. Plos One. 11: e0149941. PMID 26953569 DOI: 10.1371/journal.pone.0149941  1
2016 Young JA, List EO, Kopchick JJ. Deconstructing the Growth Hormone Receptor(GHR): Physical and Metabolic Phenotypes of Tissue-Specific GHR Gene-Disrupted Mice. Progress in Molecular Biology and Translational Science. 138: 27-39. PMID 26940385 DOI: 10.1016/bs.pmbts.2015.10.014  1
2016 Bartke A, List EO, Kopchick JJ. The somatotropic axis and aging: Benefits of endocrine defects. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 27: 41-45. PMID 26925766 DOI: 10.1016/j.ghir.2016.02.002  1
2016 Spadaro O, Goldberg EL, Camell CD, Youm YH, Kopchick JJ, Nguyen KY, Bartke A, Sun LY, Dixit VD. Growth Hormone Receptor Deficiency Protects against Age-Related NLRP3 Inflammasome Activation and Immune Senescence. Cell Reports. PMID 26876170 DOI: 10.1016/j.celrep.2016.01.044  1
2016 Jara A, Kopchick JJ. Young at Heart. Endocrinology. 157: 44-5. PMID 26717472 DOI: 10.1210/en.2015-1977  1
2016 Berryman DE, Henry B, Hjortebjerg R, List EO, Kopchick JJ. Developments in our understanding of the effects of growth hormone on white adipose tissue from mice: Implications to the clinic Expert Review of Endocrinology and Metabolism. 11: 197-207. DOI: 10.1586/17446651.2016.1147950  1
2015 Allen DB, Backeljauw P, Bidlingmaier M, Biller B, Boguszewski M, Burman P, Butler G, Chihara K, Christiansen JS, Cianfarani S, Clayton PE, Clemmons D, Cohen P, Darendeliler F, Deal C, ... ... Kopchick JJ, et al. Growth Hormone Safety Workshop Position Paper: a critical appraisal of recombinant human growth hormone therapy in children and adults. European Journal of Endocrinology / European Federation of Endocrine Societies. PMID 26563978 DOI: 10.1530/EJE-15-0873  1
2015 Stout MB, Swindell WR, Zhi X, Rohde K, List EO, Berryman DE, Kopchick JJ, Gesing A, Fang Y, Masternak MM. Transcriptome profiling reveals divergent expression shifts in brown and white adipose tissue from long-lived GHRKO mice. Oncotarget. 6: 26702-15. PMID 26436954 DOI: 10.18632/oncotarget.5760  1
2015 Comisford R, Lubbers ER, Householder LA, Suer O, Tchkonia T, Kirkland JL, List EO, Kopchick JJ, Berryman DE. Growth Hormone Receptor Antagonist Transgenic Mice Have Increased Subcutaneous Adipose Tissue Mass, Altered Glucose Homeostasis and No Change in White Adipose Tissue Cellular Senescence. Gerontology. PMID 26372907 DOI: 10.1159/000439050  1
2015 Sadagurski M, Landeryou T, Cady G, Kopchick JJ, List EO, Berryman DE, Bartke A, Miller RA. Growth hormone modulates hypothalamic inflammation in long-lived pituitary dwarf mice. Aging Cell. PMID 26268661 DOI: 10.1111/acel.12382  1
2015 List EO, Berryman DE, Ikeno Y, Hubbard GB, Funk K, Comisford R, Young JA, Stout MB, Tchkonia T, Masternak MM, Bartke A, Kirkland JL, Miller RA, Kopchick JJ. Removal of growth hormone receptor (GHR) in muscle of male mice replicates some of the health benefits seen in global GHR-/- mice. Aging. 7: 500-12. PMID 26233957  0.88
2015 Kopchick JJ. Lessons learned from studies with the growth hormone receptor. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. PMID 26216709 DOI: 10.1016/j.ghir.2015.06.003  1
2015 Cordoba-Chacon J, Majumdar N, List EO, Diaz-Ruiz A, Frank SJ, Manzano A, Bartrons R, Puchowicz M, Kopchick JJ, Kineman RD. Growth hormone inhibits hepatic de novo lipogenesis in adult mice. Diabetes. PMID 26015548 DOI: 10.2337/db15-0370  1
2015 López-Villar E, Martos-Moreno GÁ, Chowen JA, Okada S, Kopchick JJ, Argente J. A proteomic approach to obesity and type 2 diabetes. Journal of Cellular and Molecular Medicine. 19: 1455-70. PMID 25960181 DOI: 10.1111/jcmm.12600  0.76
2015 Olarescu NC, Berryman DE, Householder LA, Lubbers ER, List EO, Benencia F, Kopchick JJ, Bollerslev J. GH action influences adipogenesis of mouse adipose tissue-derived mesenchymal stem cells. The Journal of Endocrinology. 226: 13-23. PMID 25943560 DOI: 10.1530/JOE-15-0012  1
2015 Longo VD, Antebi A, Bartke A, Barzilai N, Brown-Borg HM, Caruso C, Curiel TJ, de Cabo R, Franceschi C, Gems D, Ingram DK, Johnson TE, Kennedy BK, Kenyon C, Klein S, ... Kopchick JJ, et al. Interventions to Slow Aging in Humans: Are We Ready? Aging Cell. 14: 497-510. PMID 25902704 DOI: 10.1111/acel.12338  1
2015 Zawada I, Masternak MM, List EO, Stout MB, Berryman DE, Lewinski A, Kopchick JJ, Bartke A, Karbownik-Lewinska M, Gesing A. Gene expression of key regulators of mitochondrial biogenesis is sex dependent in mice with growth hormone receptor deletion in liver. Aging. 7: 195-204. PMID 25855408  1
2015 Bartke A, Kopchick JJ. The forgotten lactogenic activity of growth hormone: important implications for rodent studies. Endocrinology. 156: 1620-2. PMID 25730109 DOI: 10.1210/en.2015-1097  1
2015 Arum O, Dawson JA, Smith DL, Kopchick JJ, Allison DB, Bartke A. Do altered energy metabolism or spontaneous locomotion 'mediate' decelerated senescence? Aging Cell. 14: 483-90. PMID 25720347 DOI: 10.1111/acel.12318  1
2015 Hascup ER, Wang F, Kopchick JJ, Bartke A. Inflammatory and Glutamatergic Homeostasis Are Involved in Successful Aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 25711529 DOI: 10.1093/gerona/glv010  1
2015 Christensen B, Ludvigsen M, Nellemann B, Kopchick JJ, Honoré B, Jørgensen JO. Serum proteomic changes after randomized prolonged erythropoietin treatment and/or endurance training: detection of novel biomarkers. Plos One. 10: e0117119. PMID 25679398 DOI: 10.1371/journal.pone.0117119  1
2015 Lim SV, Marenzana M, Hopkinson M, List EO, Kopchick JJ, Pereira M, Javaheri B, Roux JP, Chavassieux P, Korbonits M, Chenu C. Excessive growth hormone expression in male GH transgenic mice adversely alters bone architecture and mechanical strength. Endocrinology. 156: 1362-71. PMID 25646711 DOI: 10.1210/en.2014-1572  1
2015 Benencia F, Harshman S, Duran-Ortiz S, Lubbers ER, List EO, Householder L, Al-Naeeli M, Liang X, Welch L, Kopchick JJ, Berryman DE. Male bovine GH transgenic mice have decreased adiposity with an adipose depot-specific increase in immune cell populations. Endocrinology. 156: 1794-803. PMID 25521584 DOI: 10.1210/en.2014-1794  1
2015 Dominick G, Berryman DE, List EO, Kopchick JJ, Li X, Miller RA, Garcia GG. Regulation of mTOR activity in Snell dwarf and GH receptor gene-disrupted mice. Endocrinology. 156: 565-75. PMID 25456069 DOI: 10.1210/en.2014-1690  1
2015 Yang T, Householder LA, Lubbers ER, List EO, Troike K, Vesel C, Duran-Ortiz S, Kopchick JJ, Berryman DE. Growth hormone receptor antagonist transgenic mice are protected from hyperinsulinemia and glucose intolerance despite obesity when placed on a HF diet. Endocrinology. 156: 555-64. PMID 25406017 DOI: 10.1210/en.2014-1617  1
2015 Gesing A, Wang F, List EO, Berryman DE, Masternak MM, Lewinski A, Karbownik-Lewinska M, Kopchick JJ, Bartke A. Expression of apoptosis-related genes in liver-specific growth hormone receptor gene-disrupted mice is sex dependent. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 70: 44-52. PMID 24550353 DOI: 10.1093/gerona/glu008  1
2014 Arum O, Saleh J, Boparai R, Turner J, Kopchick J, Khardori R, Bartke A. Interaction of growth hormone receptor/binding protein gene disruption and caloric restriction for insulin sensitivity and attenuated aging. F1000research. 3: 256. PMID 25789159 DOI: 10.12688/f1000research.5378.1  1
2014 Arum O, Boparai RK, Saleh JK, Wang F, Dirks AL, Turner JG, Kopchick JJ, Liu JL, Khardori RK, Bartke A. Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted (GHR-KO) mice attenuates phenotypic features of slow aging. Aging Cell. 13: 981-1000. PMID 25244225 DOI: 10.1111/acel.12262  1
2014 Baquedano E, Ruiz-Lopez AM, Sustarsic EG, Herpy J, List EO, Chowen JA, Frago LM, Kopchick JJ, Argente J. The absence of GH signaling affects the susceptibility to high-fat diet-induced hypothalamic inflammation in male mice. Endocrinology. 155: 4856-67. PMID 25237935 DOI: 10.1210/en.2014-1367  1
2014 Brown-Borg HM, Rakoczy SG, Wonderlich JA, Rojanathammanee L, Kopchick JJ, Armstrong V, Raasakka D. Growth hormone signaling is necessary for lifespan extension by dietary methionine. Aging Cell. 13: 1019-27. PMID 25234161 DOI: 10.1111/acel.12269  1
2014 Schneider A, Zhi X, Bartke A, Kopchick JJ, Masternak MM. Effect of growth hormone receptor gene disruption and PMA treatment on the expression of genes involved in primordial follicle activation in mice ovaries. Age (Dordrecht, Netherlands). 36: 9701. PMID 25099774 DOI: 10.1007/s11357-014-9701-9  1
2014 Stout MB, Tchkonia T, Pirtskhalava T, Palmer AK, List EO, Berryman DE, Lubbers ER, Escande C, Spong A, Masternak MM, Oberg AL, LeBrasseur NK, Miller RA, Kopchick JJ, Bartke A, et al. Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice. Aging. 6: 575-86. PMID 25063774  1
2014 Martos-Moreno GÁ, Sackmann-Sala L, Barrios V, Berrymann DE, Okada S, Argente J, Kopchick JJ. Proteomic analysis allows for early detection of potential markers of metabolic impairment in very young obese children. International Journal of Pediatric Endocrinology. 2014: 9. PMID 24949022 DOI: 10.1186/1687-9856-2014-9  0.76
2014 Cheng CW, Adams GB, Perin L, Wei M, Zhou X, Lam BS, Da Sacco S, Mirisola M, Quinn DI, Dorff TB, Kopchick JJ, Longo VD. Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression. Cell Stem Cell. 14: 810-23. PMID 24905167 DOI: 10.1016/j.stem.2014.04.014  1
2014 Arum O, Saleh JK, Boparai RK, Kopchick JJ, Khardori RK, Bartke A. Preservation of blood glucose homeostasis in slow-senescing somatotrophism-deficient mice subjected to intermittent fasting begun at middle or old age. Age (Dordrecht, Netherlands). 36: 9651. PMID 24789008 DOI: 10.1007/s11357-014-9651-2  1
2014 List EO, Berryman DE, Funk K, Jara A, Kelder B, Wang F, Stout MB, Zhi X, Sun L, White TA, LeBrasseur NK, Pirtskhalava T, Tchkonia T, Jensen EA, Zhang W, ... ... Kopchick JJ, et al. Liver-specific GH receptor gene-disrupted (LiGHRKO) mice have decreased endocrine IGF-I, increased local IGF-I, and altered body size, body composition, and adipokine profiles. Endocrinology. 155: 1793-805. PMID 24517230 DOI: 10.1210/en.2013-2086  1
2014 Jara A, Benner CM, Sim D, Liu X, List EO, Householder LA, Berryman DE, Kopchick JJ. Elevated systolic blood pressure in male GH transgenic mice is age dependent. Endocrinology. 155: 975-86. PMID 24424040 DOI: 10.1210/en.2013-1899  1
2014 Nielsen RH, Clausen NM, Schjerling P, Larsen JO, Martinussen T, List EO, Kopchick JJ, Kjaer M, Heinemeier KM. Chronic alterations in growth hormone/insulin-like growth factor-I signaling lead to changes in mouse tendon structure. Matrix Biology : Journal of the International Society For Matrix Biology. 34: 96-104. PMID 24080228 DOI: 10.1016/j.matbio.2013.09.005  1
2014 Kopchick JJ, List EO, Kelder B, Gosney ES, Berryman DE. Evaluation of growth hormone (GH) action in mice: discovery of GH receptor antagonists and clinical indications. Molecular and Cellular Endocrinology. 386: 34-45. PMID 24035867 DOI: 10.1016/j.mce.2013.09.004  1
2014 Sackmann-Sala L, Berryman DE, Lubbers ER, Zhang H, Vesel CB, Troike KM, Gosney ES, List EO, Kopchick JJ. Age-related and depot-specific changes in white adipose tissue of growth hormone receptor-null mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 69: 34-43. PMID 23873966 DOI: 10.1093/gerona/glt110  1
2014 Arum O, Rickman DJ, Kopchick JJ, Bartke A. The slow-aging growth hormone receptor/binding protein gene-disrupted (GHR-KO) mouse is protected from aging-resultant neuromusculoskeletal frailty. Age (Dordrecht, Netherlands). 36: 117-27. PMID 23824747 DOI: 10.1007/s11357-013-9551-x  1
2014 Hong SL, Longo KA, Gosney E, Kopchick JJ. Increased metabolic flexibility and complexity in a long-lived growth hormone insensitive mouse model. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 69: 274-81. PMID 23788654 DOI: 10.1093/gerona/glt090  1
2014 Berryman DE, Lubbers ER, Magon V, List EO, Kopchick JJ. A dwarf mouse model with decreased GH/IGF-1 activity that does not experience life-span extension: potential impact of increased adiposity, leptin, and insulin with advancing age. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 69: 131-41. PMID 23695394 DOI: 10.1093/gerona/glt069  1
2013 Berryman DE, List EO, Kopchick JJ. Repression of GH signaling: one extended life to live! Aging. 5: 723-4. PMID 24142421  1
2013 Sustarsic EG, Junnila RK, Kopchick JJ. Human metastatic melanoma cell lines express high levels of growth hormone receptor and respond to GH treatment. Biochemical and Biophysical Research Communications. 441: 144-50. PMID 24134847 DOI: 10.1016/j.bbrc.2013.10.023  1
2013 S?uczanowska-G??bowska S, Laszczy?ska M, Piotrowska K, G??bowski W, Rumianowski B, Masternak M, Arum O, Kucia M, Kopchick JJ, Bartke A, Ratajczak MZ. The effect of calorie restriction on the presence of apoptotic ovarian cells in normal wild type mice and low-plasma-IGF-1 Laron dwarf mice. Journal of Ovarian Research. 6: 67. PMID 24063422 DOI: 10.1186/1757-2215-6-67  1
2013 Junnila RK, Kopchick JJ. Significance of the disulphide bonds of human growth hormone. Endokrynologia Polska. 64: 300-5. PMID 24002958 DOI: 10.5603/EP.2013.0009  1
2013 Li X, Bartke A, Berryman DE, Funk K, Kopchick JJ, List EO, Sun L, Miller RA. Direct and indirect effects of growth hormone receptor ablation on liver expression of xenobiotic metabolizing genes. American Journal of Physiology. Endocrinology and Metabolism. 305: E942-50. PMID 23941873 DOI: 10.1152/ajpendo.00304.2013  1
2013 Piotrowska K, Borkowska SJ, Wiszniewska B, LaszczyÅ„ska M, SÅ‚uczanowska-GÅ‚abowska S, Havens AM, Kopchick JJ, Bartke A, Taichman RS, Kucia M, Ratajczak MZ. The effect of low and high plasma levels of insulin-like growth factor-1 (IGF-1) on the morphology of major organs: studies of Laron dwarf and bovine growth hormone transgenic (bGHTg) mice. Histology and Histopathology. 28: 1325-36. PMID 23613169  1
2013 Junnila RK, List EO, Berryman DE, Murrey JW, Kopchick JJ. The GH/IGF-1 axis in ageing and longevity. Nature Reviews. Endocrinology. 9: 366-76. PMID 23591370 DOI: 10.1038/nrendo.2013.67  1
2013 Deal CL, Tony M, Höybye C, Allen DB, Tauber M, Christiansen JS. GrowthHormone Research Society workshop summary: consensus guidelines for recombinant human growth hormone therapy in Prader-Willi syndrome. The Journal of Clinical Endocrinology and Metabolism. 98: E1072-87. PMID 23543664 DOI: 10.1210/jc.2012-3888  1
2013 List EO, Berryman DE, Funk K, Gosney ES, Jara A, Kelder B, Wang X, Kutz L, Troike K, Lozier N, Mikula V, Lubbers ER, Zhang H, Vesel C, Junnila RK, ... ... Kopchick JJ, et al. The role of GH in adipose tissue: lessons from adipose-specific GH receptor gene-disrupted mice. Molecular Endocrinology (Baltimore, Md.). 27: 524-35. PMID 23349524 DOI: 10.1210/me.2012-1330  1
2013 Jara A, Kopchick JJ. Proteomics: A comprehensive approach Anales De Pediatria. 78: 137-139. PMID 23265721 DOI: 10.1016/j.anpedi.2012.10.007  1
2013 Lubbers ER, List EO, Jara A, Sackman-Sala L, Cordoba-Chacon J, Gahete MD, Kineman RD, Boparai R, Bartke A, Kopchick JJ, Berryman DE. Adiponectin in mice with altered GH action: links to insulin sensitivity and longevity? The Journal of Endocrinology. 216: 363-74. PMID 23261955 DOI: 10.1530/JOE-12-0505  1
2013 List EO, Berryman DE, Wright-Piekarski J, Jara A, Funk K, Kopchick JJ. The effects of weight cycling on lifespan in male C57BL/6J mice. International Journal of Obesity (2005). 37: 1088-94. PMID 23229739 DOI: 10.1038/ijo.2012.203  1
2013 Martos-Moreno GA, Kopchick JJ, Argente J. Adipokines in healthy and obese children Anales De Pediatria. 78. PMID 23228441 DOI: 10.1016/j.anpedi.2012.10.008  1
2013 Martos-Moreno GA, Sackmann-Sala L, Berryman DE, Blome DW, Argente J, Kopchick JJ. [Anatomical heterogeneity in the proteome of human subcutaneous adipose tissue]. Anales De Pediatría (Barcelona, Spain : 2003). 78: 140-8. PMID 23228439 DOI: 10.1016/j.anpedi.2012.10.010  0.88
2013 Gesing A, Masternak MM, Lewinski A, Karbownik-Lewinska M, Kopchick JJ, Bartke A. Decreased levels of proapoptotic factors and increased key regulators of mitochondrial biogenesis constitute new potential beneficial features of long-lived growth hormone receptor gene-disrupted mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 68: 639-51. PMID 23197187 DOI: 10.1093/gerona/gls231  1
2013 Ding J, Sackmann-Sala L, Kopchick JJ. Mouse models of growth hormone action and aging: a proteomic perspective. Proteomics. 13: 674-85. PMID 23019135 DOI: 10.1002/pmic.201200271  1
2013 Luca G, Calvitti M, Mancuso F, Falabella G, Arato I, Bellucci C, List EO, Bellezza E, Angeli G, Lilli C, Bodo M, Becchetti E, Kopchick JJ, Cameron DF, Baroni T, et al. Reversal of experimental Laron Syndrome by xenotransplantation of microencapsulated porcine Sertoli cells. Journal of Controlled Release : Official Journal of the Controlled Release Society. 165: 75-81. PMID 22964394 DOI: 10.1016/j.jconrel.2012.08.028  1
2013 Kucia M, Masternak M, Liu R, Shin DM, Ratajczak J, Mierzejewska K, Spong A, Kopchick JJ, Bartke A, Ratajczak MZ. The negative effect of prolonged somatotrophic/insulin signaling on an adult bone marrow-residing population of pluripotent very small embryonic-like stem cells (VSELs). Age (Dordrecht, Netherlands). 35: 315-30. PMID 22218782 DOI: 10.1007/s11357-011-9364-8  1
2012 Giani JF, Miquet JG, Muñoz MC, Burghi V, Toblli JE, Masternak MM, Kopchick JJ, Bartke A, Turyn D, Dominici FP. Upregulation of the angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas receptor axis in the heart and the kidney of growth hormone receptor knock-out mice. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 22: 224-33. PMID 22947377 DOI: 10.1016/j.ghir.2012.08.003  1
2012 S?uczanowska-G??bowska S, Laszczy?ska M, Piotrowska K, G??bowski W, Kopchick JJ, Bartke A, Kucia M, Ratajczak MZ. Morphology of ovaries in laron dwarf mice, with low circulating plasma levels of insulin-like growth factor-1 (IGF-1), and in bovine GH-transgenic mice, with high circulating plasma levels of IGF-1. Journal of Ovarian Research. 5: 18. PMID 22747742 DOI: 10.1186/1757-2215-5-18  1
2012 Burgos-Ramos E, Sackmann-Sala L, Baquedano E, Cruz-Topete D, Barrios V, Argente J, Kopchick JJ. Central leptin and insulin administration modulates serum cytokine- and lipoprotein-related markers. Metabolism: Clinical and Experimental. 61: 1646-57. PMID 22658937 DOI: 10.1016/j.metabol.2012.05.001  0.76
2012 Christensen B, Lundby C, Jessen N, Nielsen TS, Vestergaard PF, Møller N, Pilegaard H, Pedersen SB, Kopchick JJ, Jørgensen JO. Evaluation of functional erythropoietin receptor status in skeletal muscle in vivo: acute and prolonged studies in healthy human subjects. Plos One. 7: e31857. PMID 22384088 DOI: 10.1371/journal.pone.0031857  1
2012 Ding J, Berryman DE, Jara A, Kopchick JJ. Age- and sex-associated plasma proteomic changes in growth hormone receptor gene-disrupted mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 67: 830-40. PMID 22156438 DOI: 10.1093/gerona/glr212  1
2012 Masternak MM, Bartke A, Wang F, Spong A, Gesing A, Fang Y, Salmon AB, Hughes LF, Liberati T, Boparai R, Kopchick JJ, Westbrook R. Metabolic effects of intra-abdominal fat in GHRKO mice. Aging Cell. 11: 73-81. PMID 22040032 DOI: 10.1111/j.1474-9726.2011.00763.x  1
2012 Sackmann-Sala L, Berryman DE, Lubbers ER, Vesel CB, Troike KM, List EO, Munn RD, Ikeno Y, Kopchick JJ. Decreased insulin sensitivity and increased oxidative damage in wasting adipose tissue depots of wild-type mice. Age (Dordrecht, Netherlands). 34: 1225-37. PMID 21953241 DOI: 10.1007/s11357-011-9304-7  1
2012 Sackmann-Sala L, Berryman DE, Munn RD, Lubbers ER, Kopchick JJ. Heterogeneity among white adipose tissue depots in male C57BL/6J mice. Obesity (Silver Spring, Md.). 20: 101-11. PMID 21779095 DOI: 10.1038/oby.2011.235  1
2011 Liang R, Khanna A, Muthusamy S, Li N, Sarojini H, Kopchick JJ, Masternak MM, Bartke A, Wang E. Post-transcriptional regulation of IGF1R by key microRNAs in long-lived mutant mice. Aging Cell. 10: 1080-8. PMID 21967153 DOI: 10.1111/j.1474-9726.2011.00751.x  1
2011 Ding J, List EO, Bower BD, Kopchick JJ. Differential effects of growth hormone versus insulin-like growth factor-I on the mouse plasma proteome. Endocrinology. 152: 3791-802. PMID 21791560 DOI: 10.1210/en.2011-1217  1
2011 Longo KA, Govek EK, Nolan A, McDonagh T, Charoenthongtrakul S, Giuliana DJ, Morgan K, Hixon J, Zhou C, Kelder B, Kopchick JJ, Saunders JO, Navia MA, Curtis R, DiStefano PS, et al. Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity. The Journal of Pharmacology and Experimental Therapeutics. 339: 115-24. PMID 21775475 DOI: 10.1124/jpet.111.183764  1
2011 Ding J, Okada S, Jørgensen JO, Kopchick JJ. Novel serum protein biomarkers indicative of growth hormone doping in healthy human subjects. Proteomics. 11: 3565-71. PMID 21751372 DOI: 10.1002/pmic.201100077  1
2011 Martin BT, List EO, Kopchick JJ, Sauvé Y, Harvey S. Selective inner retinal dysfunction in growth hormone transgenic mice. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 21: 219-27. PMID 21705251 DOI: 10.1016/j.ghir.2011.05.008  1
2011 Cruz-Topete D, Jorgensen JO, Christensen B, Sackmann-Sala L, Krusenstjerna-Hafstrøm T, Jara A, Okada S, Kopchick JJ. Identification of new biomarkers of low-dose GH replacement therapy in GH-deficient patients. The Journal of Clinical Endocrinology and Metabolism. 96: 2089-97. PMID 21543428 DOI: 10.1210/jc.2011-0197  0.76
2011 Berryman DE, List EO, Sackmann-Sala L, Lubbers E, Munn R, Kopchick JJ. Growth hormone and adipose tissue: beyond the adipocyte. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 21: 113-23. PMID 21470887 DOI: 10.1016/j.ghir.2011.03.002  1
2011 Ding J, Berryman DE, Kopchick JJ. Plasma proteomic profiles of bovine growth hormone transgenic mice as they age. Transgenic Research. 20: 1305-20. PMID 21365322 DOI: 10.1007/s11248-011-9499-5  1
2011 Cruz-Topete D, List EO, Okada S, Kelder B, Kopchick JJ. Proteomic changes in the heart of diet-induced pre-diabetic mice. Journal of Proteomics. 74: 716-27. PMID 21354350 DOI: 10.1016/j.jprot.2011.02.018  1
2011 Fukushima T, Arai T, Ariga-Nedachi M, Okajima H, Ooi Y, Iijima Y, Sone M, Cho Y, Ando Y, Kasahara K, Ozoe A, Yoshihara H, Chida K, Okada S, Kopchick JJ, et al. Insulin receptor substrates form high-molecular-mass complexes that modulate their availability to insulin/insulin-like growth factor-I receptor tyrosine kinases. Biochemical and Biophysical Research Communications. 404: 767-73. PMID 21168390 DOI: 10.1016/j.bbrc.2010.12.045  0.76
2011 List EO, Sackmann-Sala L, Berryman DE, Funk K, Kelder B, Gosney ES, Okada S, Ding J, Cruz-Topete D, Kopchick JJ. Endocrine parameters and phenotypes of the growth hormone receptor gene disrupted (GHR-/-) mouse. Endocrine Reviews. 32: 356-86. PMID 21123740 DOI: 10.1210/er.2010-0009  1
2011 Cruz-Topete D, Christensen B, Sackmann-Sala L, Okada S, Jorgensen JO, Kopchick JJ. Serum proteome changes in acromegalic patients following transsphenoidal surgery: novel biomarkers of disease activity. European Journal of Endocrinology / European Federation of Endocrine Societies. 164: 157-67. PMID 21059862 DOI: 10.1530/EJE-10-0754  0.76
2011 Neggers SJ, Kopchick JJ, Jørgensen JO, van der Lely AJ. Hypothesis: Extra-hepatic acromegaly: a new paradigm? European Journal of Endocrinology / European Federation of Endocrine Societies. 164: 11-6. PMID 21045065 DOI: 10.1530/EJE-10-0969  1
2011 Christensen B, Sackmann-Sala L, Cruz-Topete D, Jørgensen JO, Jessen N, Lundby C, Kopchick JJ. Novel serum biomarkers for erythropoietin use in humans: a proteomic approach. Journal of Applied Physiology (Bethesda, Md. : 1985). 110: 149-56. PMID 20966191 DOI: 10.1152/japplphysiol.00665.2010  1
2011 Ding J, Kopchick JJ. Plasma biomarkers of mouse aging. Age (Dordrecht, Netherlands). 33: 291-307. PMID 20842533 DOI: 10.1007/s11357-010-9179-z  1
2011 Kopchick JJ, Tanda H, Berryman DE, Laron Z. Conclusions and future studies Laron Syndrome - From Man to Mouse: Lessons From Clinical and Experimental Experience. 513-520. DOI: 10.1007/978-3-642-11183-9_59  1
2011 Bower BD, Kopchick JJ. Cancer Laron Syndrome - From Man to Mouse: Lessons From Clinical and Experimental Experience. 495-505. DOI: 10.1007/978-3-642-11183-9_57  1
2011 Gosney ES, Kopchick JJ. GHR knockout and the CNS Laron Syndrome - From Man to Mouse: Lessons From Clinical and Experimental Experience. 489-493. DOI: 10.1007/978-3-642-11183-9_56  1
2011 Cruz-Topete D, Kopchick JJ. Cardiac function in GHR-/-mice Laron Syndrome - From Man to Mouse: Lessons From Clinical and Experimental Experience. 473-479. DOI: 10.1007/978-3-642-11183-9_54  1
2011 Ding J, Kopchick JJ. Skeletal muscle Laron Syndrome - From Man to Mouse: Lessons From Clinical and Experimental Experience. 465-471. DOI: 10.1007/978-3-642-11183-9_53  1
2011 Sackmann-Sala L, Miles DRB, Kopchick JJ. Metabolism and metabolic regulation Laron Syndrome - From Man to Mouse: Lessons From Clinical and Experimental Experience. 451-463. DOI: 10.1007/978-3-642-11183-9_52  1
2011 Kopchick JJ, Blischak JD. The Laron mouse Laron Syndrome - From Man to Mouse: Lessons From Clinical and Experimental Experience. 429-432. DOI: 10.1007/978-3-642-11183-9_49  1
2011 Laron Z, Kopchick JJ. Preface Laron Syndrome - From Man to Mouse: Lessons From Clinical and Experimental Experience. DOI: 10.1007/978-3-642-11183-9  1
2010 Rouet V, Bogorad RL, Kayser C, Kessal K, Genestie C, Bardier A, Grattan DR, Kelder B, Kopchick JJ, Kelly PA, Goffin V. Local prolactin is a target to prevent expansion of basal/stem cells in prostate tumors. Proceedings of the National Academy of Sciences of the United States of America. 107: 15199-204. PMID 20699217 DOI: 10.1073/pnas.0911651107  1
2010 Coschigano KT, Wetzel AN, Obichere N, Sharma A, Lee S, Rasch R, Guigneaux MM, Flyvbjerg A, Wood TG, Kopchick JJ. Identification of differentially expressed genes in the kidneys of growth hormone transgenic mice Growth Hormone and Igf Research. 20: 345-355. PMID 20655258 DOI: 10.1016/j.ghir.2010.06.001  1
2010 Okada S, List EO, Sankaran S, Kopchick JJ. Plasma Protein Biomarkers Correlated with the Development of Diet-Induced Type 2 Diabetes in Mice. Clinical Proteomics. 6: 6-17. PMID 20625478 DOI: 10.1007/s12014-009-9040-5  1
2010 Doi SQ, Chilakamarri GC, Mendonca MC, Araujo M, Nguyen N, Zuhl I, List EO, Kopchick JJ, Hirata MH, Sellitti DF. Increased class A scavenger receptor and glomerular lipid precede mesangial matrix expansion in the bGH mouse model. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 20: 326-32. PMID 20576456 DOI: 10.1016/j.ghir.2010.05.002  1
2010 Xu J, Okada S, Tan L, Goodrum KJ, Kopchick JJ, Kieliszewski MJ. Human growth hormone expressed in tobacco cells as an arabinogalactan-protein fusion glycoprotein has a prolonged serum life. Transgenic Research. 19: 849-67. PMID 20135224 DOI: 10.1007/s11248-010-9367-8  0.76
2010 Berryman DE, List EO, Palmer AJ, Chung MY, Wright-Piekarski J, Lubbers E, O'Connor P, Okada S, Kopchick JJ. Two-year body composition analyses of long-lived GHR null mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 65: 31-40. PMID 19901018 DOI: 10.1093/gerona/glp175  1
2010 Callewaert F, Venken K, Kopchick JJ, Torcasio A, van Lenthe GH, Boonen S, Vanderschueren D. Sexual dimorphism in cortical bone size and strength but not density is determined by independent and time-specific actions of sex steroids and IGF-1: evidence from pubertal mouse models. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 617-26. PMID 19888832 DOI: 10.1359/jbmr.090828  1
2010 Longo KA, Berryman DE, Kelder B, Charoenthongtrakul S, Distefano PS, Geddes BJ, Kopchick JJ. Daily energy balance in growth hormone receptor/binding protein (GHR -/-) gene-disrupted mice is achieved through an increase in dark-phase energy efficiency. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 20: 73-9. PMID 19747867 DOI: 10.1016/j.ghir.2009.08.002  1
2009 Ding J, List EO, Okada S, Kopchick JJ. Perspective: proteomic approach to detect biomarkers of human growth hormone. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 19: 399-407. PMID 19501004 DOI: 10.1016/j.ghir.2009.04.018  1
2009 List EO, Palmer AJ, Berryman DE, Bower B, Kelder B, Kopchick JJ. Growth hormone improves body composition, fasting blood glucose, glucose tolerance and liver triacylglycerol in a mouse model of diet-induced obesity and type 2 diabetes Diabetologia. 52: 1647-1655. PMID 19468705 DOI: 10.1007/s00125-009-1402-z  1
2009 Fan Y, Menon RK, Cohen P, Hwang D, Clemens T, DiGirolamo DJ, Kopchick JJ, Le Roith D, Trucco M, Sperling MA. Liver-specific deletion of the growth hormone receptor reveals essential role of growth hormone signaling in hepatic lipid metabolism. The Journal of Biological Chemistry. 284: 19937-44. PMID 19460757 DOI: 10.1074/jbc.M109.014308  1
2009 Swindell WR, Masternak MM, Kopchick JJ, Conover CA, Bartke A, Miller RA. Endocrine regulation of heat shock protein mRNA levels in long-lived dwarf mice. Mechanisms of Ageing and Development. 130: 393-400. PMID 19428459 DOI: 10.1016/j.mad.2009.03.004  1
2009 Sackmann-Sala L, Ding J, Frohman LA, Kopchick JJ. Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 19: 471-7. PMID 19386527 DOI: 10.1016/j.ghir.2009.03.001  1
2009 Izzard AS, Emerson M, Prehar S, Neyses L, Trainer P, List EO, Kopchick JJ, Heagerty AM. The cardiovascular phenotype of a mouse model of acromegaly. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 19: 413-9. PMID 19269870 DOI: 10.1016/j.ghir.2008.12.006  1
2009 Bonkowski MS, Dominici FP, Arum O, Rocha JS, Al Regaiey KA, Westbrook R, Spong A, Panici J, Masternak MM, Kopchick JJ, Bartke A. Disruption of growth hormone receptor prevents calorie restriction from improving insulin action and longevity. Plos One. 4: e4567. PMID 19234595 DOI: 10.1371/journal.pone.0004567  1
2009 Ikeno Y, Hubbard GB, Lee S, Cortez LA, Lew CM, Webb CR, Berryman DE, List EO, Kopchick JJ, Bartke A. Reduced incidence and delayed occurrence of fatal neoplastic diseases in growth hormone receptor/binding protein knockout mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 522-9. PMID 19228785 DOI: 10.1093/gerona/glp017  1
2009 Bartke A, Kopchick J. Comment on: Kloting et al. (2008) Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth: Diabetes 57:2074-2082. Diabetes. 58: e3; author reply e4. PMID 19114718 DOI: 10.2337/db08-1308  1
2009 Kraemer WJ, Vingren JL, Schuenke MD, Kopchick JJ, Volek JS, Fragala MS, Häkkinen K, Jen-Ho, Thomas GA, Staron RS. Effect of circulating growth hormone on muscle IGF-I protein concentration in female mice with growth hormone receptor gene disruption. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 19: 242-4. PMID 19083250 DOI: 10.1016/j.ghir.2008.10.006  1
2009 Stevenson AE, Evans BA, Gevers EF, Elford C, McLeod RW, Perry MJ, El-Kasti MM, Coschigano KT, Kopchick JJ, Evans SL, Wells T. Does adiposity status influence femoral cortical strength in rodent models of growth hormone deficiency? American Journal of Physiology. Endocrinology and Metabolism. 296: E147-56. PMID 19001545 DOI: 10.1152/ajpendo.90689.2008  1
2009 Nass R, Johannsson G, Christiansen JS, Kopchick JJ, Thorner MO. The aging population--is there a role for endocrine interventions? Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 19: 89-100. PMID 18977675 DOI: 10.1016/j.ghir.2008.09.002  1
2009 Palmer AJ, Chung MY, List EO, Walker J, Okada S, Kopchick JJ, Berryman DE. Age-related changes in body composition of bovine growth hormone transgenic mice. Endocrinology. 150: 1353-60. PMID 18948397 DOI: 10.1210/en.2008-1199  1
2008 Berryman DE, Christiansen JS, Johannsson G, Thorner MO, Kopchick JJ. Role of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 18: 455-71. PMID 18710818 DOI: 10.1016/j.ghir.2008.05.005  1
2008 Schuenke MD, Kopchick JJ, Hikida RS, Kraemer WJ, Staron RS. Effects of growth hormone overexpression vs. growth hormone receptor gene disruption on mouse hindlimb muscle fiber type composition. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 18: 479-86. PMID 18499495 DOI: 10.1016/j.ghir.2008.04.003  1
2008 List EO, Berryman DE, Bower B, Sackmann-Sala L, Gosney E, Ding J, Okada S, Kopchick JJ. The use of proteomics to study infectious diseases. Infectious Disorders Drug Targets. 8: 31-45. PMID 18473905 DOI: 10.2174/187152608784139640  1
2008 Baudet ML, Hassanali Z, Sawicki G, List EO, Kopchick JJ, Harvey S. Growth hormone action in the developing neural retina: a proteomic analysis. Proteomics. 8: 389-401. PMID 18203262 DOI: 10.1002/pmic.200700952  1
2007 Berryman DE, Palmer AJ, Gosney ES, Swaminathan S, DeSantis D, Kopchick JJ. Discovery and uses of pegvisomant: a growth hormone antagonist. Endokrynologia Polska. 58: 322-9. PMID 18058724  1
2007 Swanson SM, Kopchick JJ. Nuclear localization of growth hormone receptor: another age of discovery for cytokine action? Science's Stke : Signal Transduction Knowledge Environment. 2007: pe69. PMID 18056914 DOI: 10.1126/stke.4152007pe69  1
2007 Chandrashekar V, Dawson CR, Martin ER, Rocha JS, Bartke A, Kopchick JJ. Age-related alterations in pituitary and testicular functions in long-lived growth hormone receptor gene-disrupted mice. Endocrinology. 148: 6019-25. PMID 17872367 DOI: 10.1210/en.2007-0837  1
2007 Kelder B, Berryman DE, Clark R, Li A, List EO, Kopchick JJ. CIDE-A gene expression is decreased in white adipose tissue of growth hormone receptor/binding protein gene disrupted mice and with high-fat feeding of normal mice. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 17: 346-51. PMID 17544797 DOI: 10.1016/j.ghir.2007.04.006  1
2007 Kelder B, Boyce K, Kriete A, Clark R, Berryman DE, Nagatomi S, List EO, Braughler M, Kopchick JJ. CIDE-A is expressed in liver of old mice and in type 2 diabetic mouse liver exhibiting steatosis. Comparative Hepatology. 6: 4. PMID 17472743 DOI: 10.1186/1476-5926-6-4  1
2007 List EO, Berryman DE, Palmer AJ, Qiu L, Sankaran S, Kohn DT, Kelder B, Okada S, Kopchick JJ. Analysis of mouse skin reveals proteins that are altered in a diet-induced diabetic state: a new method for detection of type 2 diabetes. Proteomics. 7: 1140-9. PMID 17390296 DOI: 10.1002/pmic.200600641  1
2007 Kopchick JJ, Sackmann-Sala L, Ding J. Primer: molecular tools used for the understanding of endocrinology. Nature Clinical Practice. Endocrinology & Metabolism. 3: 355-68. PMID 17377618 DOI: 10.1038/ncpendmet0446  1
2007 del Rincon JP, Iida K, Gaylinn BD, McCurdy CE, Leitner JW, Barbour LA, Kopchick JJ, Friedman JE, Draznin B, Thorner MO. Growth hormone regulation of p85alpha expression and phosphoinositide 3-kinase activity in adipose tissue: mechanism for growth hormone-mediated insulin resistance. Diabetes. 56: 1638-46. PMID 17363744 DOI: 10.2337/db06-0299  1
2007 Al-Regaiey KA, Masternak MM, Bonkowski MS, Panici JA, Kopchick JJ, Bartke A. Effects of caloric restriction and growth hormone resistance on insulin-related intermediates in the skeletal muscle. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 62: 18-26. PMID 17301033  1
2007 Reddy GR, Pushpanathan MJ, Ransom RF, Holzman LB, Brosius FC, Diakonova M, Mathieson P, Saleem MA, List EO, Kopchick JJ, Frank SJ, Menon RK. Identification of the glomerular podocyte as a target for growth hormone action. Endocrinology. 148: 2045-55. PMID 17272398 DOI: 10.1210/en.2006-1285  1
2007 Davies JS, Gevers EF, Stevenson AE, Coschigano KT, El-Kasti MM, Bull MJ, Elford C, Evans BA, Kopchick JJ, Wells T. Adiposity profile in the dwarf rat: an unusually lean model of profound growth hormone deficiency. American Journal of Physiology. Endocrinology and Metabolism. 292: E1483-94. PMID 17264226 DOI: 10.1152/ajpendo.00417.2006  0.6
2007 Venken K, Movérare-Skrtic S, Kopchick JJ, Coschigano KT, Ohlsson C, Boonen S, Bouillon R, Vanderschueren D. Impact of androgens, growth hormone, and IGF-I on bone and muscle in male mice during puberty. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 22: 72-82. PMID 17014385 DOI: 10.1080/14041040701390278  1
2007 Zhang X, Mehta RG, Lantvit DD, Coschigano KT, Kopchick JJ, Green JE, Hedayat S, Christov KT, Ray VH, Unterman TG, Swanson SM. Inhibition of estrogen-independent mammary carcinogenesis by disruption of growth hormone signaling. Carcinogenesis. 28: 143-50. PMID 16916863 DOI: 10.1093/carcin/bgl138  1
2007 Smid JR, Rowland JE, Young WG, Coschigano KT, Kopchick JJ, Waters MJ. Mouse moler dentin size/shape is dependent on growth hormone status Journal of Dental Research. 86: 463-468. DOI: 10.1177/154405910708600514  1
2007 Kopchick JJ, Sackmann-Sala L. Metabolic effects of growth hormone Anales De Pediatria. 66: 24-30. DOI: 10.1157/13097354  1
2006 Clark RP, Schuenke M, Keeton SM, Staron RS, Kopchick JJ. Effects of growth hormone and insulin-like growth factor I on muscle in mouse models of human growth disorders. Hormone Research. 66: 26-34. PMID 17259718 DOI: 10.1159/000096620  1
2006 Flint DJ, Binart N, Boumard S, Kopchick JJ, Kelly P. Developmental aspects of adipose tissue in GH receptor and prolactin receptor gene disrupted mice: site-specific effects upon proliferation, differentiation and hormone sensitivity. The Journal of Endocrinology. 191: 101-11. PMID 17065393 DOI: 10.1677/joe.1.06939  1
2006 van der Lely AJ, Kopchick JJ. Growth hormone receptor antagonists. Neuroendocrinology. 83: 264-8. PMID 17047392 DOI: 10.1159/000095537  1
2006 Manhès C, Kayser C, Bertheau P, Kelder B, Kopchick JJ, Kelly PA, Touraine P, Goffin V. Local over-expression of prolactin in differentiating mouse mammary gland induces functional defects and benign lesions, but no carcinoma. The Journal of Endocrinology. 190: 271-85. PMID 16899561 DOI: 10.1677/joe.1.06829  1
2006 Tiong JD, Gosney E, Ding J, Chin E, Kopchick JJ. A liver specific gene that is expressed in growth hormone transgenic mice and in normal female mice as a function of age. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 16: 145-56. PMID 16723264 DOI: 10.1016/j.ghir.2006.03.011  1
2006 Sotiropoulos A, Ohanna M, Kedzia C, Menon RK, Kopchick JJ, Kelly PA, Pende M. Growth hormone promotes skeletal muscle cell fusion independent of insulin-like growth factor 1 up-regulation. Proceedings of the National Academy of Sciences of the United States of America. 103: 7315-20. PMID 16670201 DOI: 10.1073/pnas.0510033103  1
2006 Robertson K, Kopchick JJ, Liu JL. Growth hormone receptor gene deficiency causes delayed insulin responsiveness in skeletal muscles without affecting compensatory islet cell overgrowth in obese mice. American Journal of Physiology. Endocrinology and Metabolism. 291: E491-8. PMID 16621895 DOI: 10.1152/ajpendo.00378.2005  1
2006 Berryman DE, List EO, Kohn DT, Coschigano KT, Seeley RJ, Kopchick JJ. Effect of growth hormone on susceptibility to diet-induced obesity. Endocrinology. 147: 2801-8. PMID 16556764 DOI: 10.1210/en.2006-0086  1
2006 Masternak MM, Al-Regaiey KA, Del Rosario Lim MM, Jimenez-Ortega V, Panici JA, Bonkowski MS, Kopchick JJ, Wang Z, Bartke A. Caloric restriction and growth hormone receptor knockout: effects on expression of genes involved in insulin action in the heart. Experimental Gerontology. 41: 417-29. PMID 16524678 DOI: 10.1016/j.exger.2006.01.009  1
2006 Beyea JA, Sawicki G, Olson DM, List E, Kopchick JJ, Harvey S. Growth hormone (GH) receptor knockout mice reveal actions of GH in lung development. Proteomics. 6: 341-8. PMID 16287172 DOI: 10.1002/pmic.200500168  1
2006 Egecioglu E, Bjursell M, Ljungberg A, Dickson SL, Kopchick JJ, Bergström G, Svensson L, Oscarsson J, Törnell J, Bohlooly-Y M. Growth hormone receptor deficiency results in blunted ghrelin feeding response, obesity, and hypolipidemia in mice. American Journal of Physiology. Endocrinology and Metabolism. 290: E317-25. PMID 16174655 DOI: 10.1152/ajpendo.00181.2005  1
2005 Masternak MM, Al-Regaiey KA, Del Rosario Lim MM, Jimenez-Ortega V, Panici JA, Bonkowski MS, Kopchick JJ, Bartke A. Effects of caloric restriction and growth hormone resistance on the expression level of peroxisome proliferator-activated receptors superfamily in liver of normal and long-lived growth hormone receptor/binding protein knockout mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 60: 1394-8. PMID 16339324  1
2005 Venken K, Schuit F, Van Lommel L, Tsukamoto K, Kopchick JJ, Coschigano K, Ohlsson C, Movérare S, Boonen S, Bouillon R, Vanderschueren D. Growth without growth hormone receptor: estradiol is a major growth hormone-independent regulator of hepatic IGF-I synthesis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 2138-49. PMID 16294267 DOI: 10.1359/JBMR.050811  1
2005 Machado MO, Hirata RD, Sellitti DF, Iotti R, Iotti A, Cusumano AM, Riordan GP, Coschigano KT, Kopchick JJ, Zuhl I, Nguyen N, Hirata MH, Doi SQ. Growth hormone promotes glomerular lipid accumulation in bGH mice. Kidney International. 68: 2019-28. PMID 16221202 DOI: 10.1111/j.1523-1755.2005.00656.x  0.6
2005 Boyce K, Kriete A, Nagatomi S, Kelder B, Coschigano K, Kopchick JJ. Phenotypical enrichment strategies for microarray data analysis applied in a type II diabetes study. Omics : a Journal of Integrative Biology. 9: 251-65. PMID 16209639 DOI: 10.1089/omi.2005.9.251  1
2005 Wang Z, Prins GS, Coschigano KT, Kopchick JJ, Green JE, Ray VH, Hedayat S, Christov KT, Unterman TG, Swanson SM. Disruption of growth hormone signaling retards early stages of prostate carcinogenesis in the C3(1)/T antigen mouse. Endocrinology. 146: 5188-96. PMID 16141391 DOI: 10.1210/en.2005-0607  1
2005 Qiu L, List EO, Kopchick JJ. Differentially expressed proteins in the pancreas of diet-induced diabetic mice. Molecular & Cellular Proteomics : McP. 4: 1311-8. PMID 15961380 DOI: 10.1074/mcp.M500016-MCP200  1
2005 Nilsson L, Binart N, Bohlooly-Y M, Bramnert M, Egecioglu E, Kindblom J, Kelly PA, Kopchick JJ, Ormandy CJ, Ling C, Billig H. Prolactin and growth hormone regulate adiponectin secretion and receptor expression in adipose tissue. Biochemical and Biophysical Research Communications. 331: 1120-6. PMID 15882993 DOI: 10.1016/j.bbrc.2005.04.026  1
2005 Guo Y, Lu Y, Houle D, Robertson K, Tang Z, Kopchick JJ, Liu YL, Liu JL. Pancreatic islet-specific expression of an insulin-like growth factor-I transgene compensates islet cell growth in growth hormone receptor gene-deficient mice. Endocrinology. 146: 2602-9. PMID 15731363 DOI: 10.1210/en.2004-1203  1
2005 Salmon AB, Murakami S, Bartke A, Kopchick J, Yasumura K, Miller RA. Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress. American Journal of Physiology. Endocrinology and Metabolism. 289: E23-9. PMID 15701676 DOI: 10.1152/ajpendo.00575.2004  1
2005 Bartke A, Heiman M, Turyn D, Dominici F, Kopchick JJ. The role of growth hormone signaling in the control of ageing Neuroimmune Biology. 4: 123-137. DOI: 10.1016/S1567-7443(04)80010-3  1
2005 Kopchick JJ, Qiu L, Gosney E, Keller C, Palmer A, Sankaran S. Growth Hormone Antagonists. A Pharmacological Tool in Present and Future Therapies The Somatotrophic Axis in Brain Function. 313-326. DOI: 10.1016/B978-012088484-1/50027-6  1
2004 Itoh E, Iida K, Kim DS, Del Rincon JP, Coschigano KT, Kopchick JJ, Thorner MO. Lack of contribution of 11betaHSD1 and glucocorticoid action to reduced muscle mass associated with reduced growth hormone action. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 14: 462-6. PMID 15519255 DOI: 10.1016/j.ghir.2004.07.002  0.6
2004 Maamra M, Kopchick JJ, Strasburger CJ, Ross RJM. Pegvisomant, a growth hormone-specific antagonist, undergoes cellular internalization Journal of Clinical Endocrinology and Metabolism. 89: 4532-4537. PMID 15356058 DOI: 10.1210/jc.2003-031781  1
2004 Bartke A, Peluso MR, Moretz N, Wright C, Bonkowski M, Winters TA, Shanahan MF, Kopchick JJ, Banz WJ. Effects of Soy-derived diets on plasma and liver lipids, glucose tolerance, and longevity in normal, long-lived and short-lived mice. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et MéTabolisme. 36: 550-8. PMID 15326565 DOI: 10.1055/s-2004-825796  1
2004 Young WG, Ramirez-Yañez GO, Daley TJ, Smid JR, Coshigano KT, Kopchick JJ, Waters MJ. Growth hormone and epidermal growth factor in salivary glands of giant and dwarf transgenic mice. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 52: 1191-7. PMID 15314086 DOI: 10.1369/jhc.4A6294.2004  1
2004 Iida K, Itoh E, Kim DS, del Rincon JP, Coschigano KT, Kopchick JJ, Thorner MO. Muscle mechano growth factor is preferentially induced by growth hormone in growth hormone-deficient lit/lit mice. The Journal of Physiology. 560: 341-9. PMID 15308683 DOI: 10.1113/jphysiol.2004.069500  0.6
2004 Pennisi PA, Kopchick JJ, Thorgeirsson S, LeRoith D, Yakar S. Role of growth hormone (GH) in liver regeneration. Endocrinology. 145: 4748-55. PMID 15242989 DOI: 10.1210/en.2004-0655  1
2004 Berryman DE, List EO, Coschigano KT, Behar K, Kim JK, Kopchick JJ. Comparing adiposity profiles in three mouse models with altered GH signaling. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 14: 309-18. PMID 15231300 DOI: 10.1016/j.ghir.2004.02.005  1
2004 Iida K, del Rincon JP, Kim DS, Itoh E, Coschigano KT, Kopchick JJ, Thorner MO. Regulation of full-length and truncated growth hormone (GH) receptor by GH in tissues of lit/lit or bovine GH transgenic mice. American Journal of Physiology. Endocrinology and Metabolism. 287: E566-73. PMID 15165994 DOI: 10.1152/ajpendo.00110.2004  0.6
2004 Liu JL, Coschigano KT, Robertson K, Lipsett M, Guo Y, Kopchick JJ, Kumar U, Liu YL. Disruption of growth hormone receptor gene causes diminished pancreatic islet size and increased insulin sensitivity in mice. American Journal of Physiology. Endocrinology and Metabolism. 287: E405-13. PMID 15138153 DOI: 10.1152/ajpendo.00423.2003  1
2004 Muller AF, Kopchick JJ, Flyvbjerg A, van der Lely AJ. Clinical review 166: Growth hormone receptor antagonists. The Journal of Clinical Endocrinology and Metabolism. 89: 1503-11. PMID 15070905 DOI: 10.1210/jc.2002-022049  1
2004 McIlwain DL, Hoke VB, Kopchick JJ, Fuller CR, Lund PK. Differential inhibition of postnatal brain, spinal cord and body growth by a growth hormone antagonist. Bmc Neuroscience. 5: 6. PMID 15018641 DOI: 10.1186/1471-2202-5-6  1
2004 Wang J, Zhou J, Cheng CM, Kopchick JJ, Bondy CA. Evidence supporting dual, IGF-I-independent and IGF-I-dependent, roles for GH in promoting longitudinal bone growth Journal of Endocrinology. 180: 247-255. PMID 14765976 DOI: 10.1677/joe.0.1800247  1
2004 Iida K, Del Rincon JP, Kim DS, Itoh E, Nass R, Coschigano KT, Kopchick JJ, Thorner MO. Tissue-specific regulation of growth hormone (GH) receptor and insulin-like growth factor-I gene expression in the pituitary and liver of GH-deficient (lit/lit) mice and transgenic mice that overexpress bovine GH (bGH) or a bGH antagonist. Endocrinology. 145: 1564-70. PMID 14726438 DOI: 10.1210/en.2003-1486  0.6
2004 Yakar S, Setser J, Zhao H, Stannard B, Haluzik M, Glatt V, Bouxsein ML, Kopchick JJ, LeRoith D. Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice. The Journal of Clinical Investigation. 113: 96-105. PMID 14702113 DOI: 10.1172/JCI17763  0.36
2004 Smid JR, Rowland JE, Young WG, Daley TJ, Coschigano KT, Kopchick JJ, Waters MJ. Mouse cellular cementum is highly dependent on growth hormone status. Journal of Dental Research. 83: 35-9. PMID 14691110  1
2003 Kopchick JJ. Discovery and development of a new class of drugs: GH antagonists Journal of Endocrinological Investigation. 26: 16-26. PMID 15497656  1
2003 Kopchick JJ. History and future of growth hormone research. Hormone Research. 60: 103-12. PMID 14671406 DOI: 10.1159/000074510  1
2003 Coschigano KT, Holland AN, Riders ME, List EO, Flyvbjerg A, Kopchick JJ. Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span. Endocrinology. 144: 3799-810. PMID 12933651 DOI: 10.1210/en.2003-0374  1
2003 Bernichtein S, Kayser C, Dillner K, Moulin S, Kopchick JJ, Martial JA, Norstedt G, Isaksson O, Kelly PA, Goffin V. Development of pure prolactin receptor antagonists. The Journal of Biological Chemistry. 278: 35988-99. PMID 12824168 DOI: 10.1074/jbc.M305687200  1
2003 Kopchick JJ. Discovery and mechanism of action of pegvisomant. European Journal of Endocrinology / European Federation of Endocrine Societies. 148: S21-5. PMID 12670297  1
2003 Parsons SA, Banks GB, Rowland JA, Coschigano KT, Kopchick JJ, Waters MJ, Noakes PG. Genetic disruption of the growth hormone receptor does not influence motoneuron survival in the developing mouse. The International Journal of Developmental Biology. 47: 41-9. PMID 12653250  1
2003 Bartke A, Chandrashekar V, Dominici F, Turyn D, Kinney B, Steger R, Kopchick JJ. Insulin-like growth factor 1 (IGF-1) and aging: controversies and new insights. Biogerontology. 4: 1-8. PMID 12652183 DOI: 10.1023/A:1022448532248  1
2003 Li Y, Knapp JR, Kopchick JJ. Enlargement of interscapular brown adipose tissue in growth hormone antagonist transgenic and in growth hormone receptor gene-disrupted dwarf mice. Experimental Biology and Medicine (Maywood, N.J.). 228: 207-15. PMID 12563029  1
2002 Kopchick JJ, List EO, Kohn DT, Keidan GM, Qiu L, Okada S. Perspective: Proteomics-See "Spots" Run. Endocrinology. 143: 1990-1994. PMID 28201417 DOI: 10.1210/endo.143.6.8882  0.84
2002 Kelly PA, Bachelot A, Kedzia C, Hennighausen L, Ormandy CJ, Kopchick JJ, Binart N. The role of prolactin and growth hormone in mammary gland development. Molecular and Cellular Endocrinology. 197: 127-31. PMID 12431805 DOI: 10.1016/S0303-7207(02)00286-1  1
2002 Miller RA, Chang Y, Galecki AT, Al-Regaiey K, Kopchick JJ, Bartke A. Gene expression patterns in calorically restricted mice: partial overlap with long-lived mutant mice. Molecular Endocrinology (Baltimore, Md.). 16: 2657-66. PMID 12403853 DOI: 10.1210/me.2002-0142  1
2002 Hauck SJ, Aaron JM, Wright C, Kopchick JJ, Bartke A. Antioxidant enzymes, free-radical damage, and response to paraquat in liver and kidney of long-living growth hormone receptor/binding protein gene-disrupted mice. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et MéTabolisme. 34: 481-6. PMID 12384824 DOI: 10.1055/s-2002-34787  1
2002 Kopchick JJ, Parkinson C, Stevens EC, Trainer PJ. Growth hormone receptor antagonists: discovery, development, and use in patients with acromegaly. Endocrine Reviews. 23: 623-46. PMID 12372843 DOI: 10.1210/er.2001-0022  1
2002 Leonard AE, Kelder B, Bobik EG, Chuang LT, Lewis CJ, Kopchick JJ, Mukerji P, Huang YS. Identification and expression of mammalian long-chain PUFA elongation enzymes. Lipids. 37: 733-40. PMID 12371743  1
2002 Zaczek D, Hammond J, Suen L, Wandji S, Service D, Bartke A, Chandrashekar V, Coschigano K, Kopchick J. Impact of growth hormone resistance on female reproductive function: new insights from growth hormone receptor knockout mice. Biology of Reproduction. 67: 1115-24. PMID 12297526  0.56
2002 Bachelot A, Monget P, Imbert-Bolloré P, Coshigano K, Kopchick JJ, Kelly PA, Binart N. Growth hormone is required for ovarian follicular growth. Endocrinology. 143: 4104-12. PMID 12239122 DOI: 10.1210/en.2002-220087  1
2002 Keene DE, Suescun MO, Bostwick MG, Chandrashekar V, Bartke A, Kopchick JJ. Puberty is delayed in male growth hormone receptor gene-disrupted mice. Journal of Andrology. 23: 661-8. PMID 12185100  1
2002 Kopchick JJ, List EO, Kohn DT, Keidan GM, Qiu L, Okada S. Perspective: proteomics--see "spots" run. Endocrinology. 143: 1990-4. PMID 12021159 DOI: 10.1210/endo.143.6.8882  1
2001 Kopchick JJ, Okada S. Growth hormone receptor antagonists: Discovery and potential uses Growth Hormone and Igf Research. 11. PMID 11527080  1
2001 Doi SQ, Rasaiah S, Tack I, Mysore J, Kopchick JJ, Moore J, Hirszel P, Striker LJ, Striker GE. Low-protein diet suppresses serum insulin-like growth factor-1 and decelerates the progression of growth hormone-induced glomerulosclerosis. American Journal of Nephrology. 21: 331-9. PMID 11509807 DOI: 10.1159/000046270  0.44
2001 Bartke A, Coschigano K, Kopchick J, Chandrashekar V, Mattison J, Kinney B, Hauck S. Genes that prolong life: relationships of growth hormone and growth to aging and life span. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 56: B340-9. PMID 11487592  0.56
2001 Pollak M, Blouin MJ, Zhang JC, Kopchick JJ. Reduced mammary gland carcinogenesis in transgenic mice expressing a growth hormone antagonist British Journal of Cancer. 85: 428-430. PMID 11487276 DOI: 10.1054/bjoc.2001.1895  1
2001 Chandrashekar V, Bartke A, Awoniyi CA, Tsai-Morris CH, Dufau ML, Russell LD, Kopchick JJ. Testicular endocrine function in GH receptor gene disrupted mice. Endocrinology. 142: 3443-50. PMID 11459789 DOI: 10.1210/endo.142.8.8298  0.56
2001 Turner ND, Knapp JR, Byers FM, Kopchick JJ. Physical and mechanical characteristics of tibias from transgenic mice expressing mutant bovine growth hormone genes Proceedings of the Society For Experimental Biology and Medicine. 226: 133-139. PMID 11446437  1
2001 Li Y, Kelder B, Kopchick JJ. Identification, isolation, and cloning of growth hormone (GH)-inducible interscapular brown adipose complementary deoxyribonucleic acid from GH antagonist mice. Endocrinology. 142: 2937-45. PMID 11416014 DOI: 10.1210/endo.142.7.8233  1
2001 Hauck SJ, Hunter WS, Danilovich N, Kopchick JJ, Bartke A. Reduced levels of thyroid hormones, insulin, and glucose, and lower body core temperature in the growth hormone receptor/binding protein knockout mouse. Experimental Biology and Medicine (Maywood, N.J.). 226: 552-8. PMID 11395925  1
2001 Kelder B, Mukeji P, Kirchner S, Hovanec G, Leonard AE, Chuang LT, Kopchick JJ, Huang YS. Expression of fungal desaturase genes in cultured mammalian cells. Molecular and Cellular Biochemistry. 219: 7-11. PMID 11354256 DOI: 10.1023/A:1011023632564  1
2001 List EO, Coschigano KT, Kopchick JJ. Growth hormone receptor/binding protein (GHR/BP) knockout mice: A 3-year update Molecular Genetics and Metabolism. 73: 1-10. PMID 11350177 DOI: 10.1006/mgme.2001.3164  1
2001 Kinney BA, Coschigano KT, Kopchick JJ, Steger RW, Bartke A. Evidence that age-induced decline in memory retention is delayed in growth hormone resistant GH-R-KO (Laron) mice. Physiology & Behavior. 72: 653-60. PMID 11336996 DOI: 10.1016/S0031-9384(01)00423-1  1
2001 Zhang Y, Guan R, Jiang J, Kopchick JJ, Black RA, Baumann G, Frank SJ. Growth Hormone (GH)-induced Dimerization Inhibits Phorbol Ester-stimulated GH Receptor Proteolysis Journal of Biological Chemistry. 276: 24565-24573. PMID 11309389 DOI: 10.1074/jbc.M101281200  1
2001 Okada S, Kopchick JJ. Biological effects of growth hormone and its antagonist Trends in Molecular Medicine. 7: 126-132. PMID 11286784 DOI: 10.1016/S1471-4914(01)01933-5  1
2001 Gallego MI, Binart N, Robinson GW, Okagaki R, Coschigano KT, Perry J, Kopchick JJ, Oka T, Kelly PA, Hennighausen L. Prolactin, growth hormone, and epidermal growth factor activate Stat5 in different compartments of mammary tissue and exert different and overlapping developmental effects. Developmental Biology. 229: 163-75. PMID 11133161 DOI: 10.1006/dbio.2000.9961  0.6
2001 Li Z, Gu T, Kelder B, Kopchick JJ. Analysis of fatty acids in mouse cells using reversed-phase high-performance liquid chromatography Chromatographia. 54: 463-467.  1
2000 Bartke A, Brown-Borg H, Kinney B, Mattison J, Wright C, Hauck S, Coschigano K, Kopchick J. Growth hormone and aging. Journal of the American Aging Association. 23: 219-25. PMID 23604867 DOI: 10.1007/s11357-000-0021-x  0.56
2000 Das T, Johns PW, Goffin V, Kelly P, Kelder B, Kopchick J, Buxton K, Mukerji P. High-level expression of biologically active human prolactin from recombinant baculovirus in insect cells. Protein Expression and Purification. 20: 265-73. PMID 11049750 DOI: 10.1006/prep.2000.1290  1
2000 Kopchick JJ, Andry JM. Growth hormone (GH), GH receptor, and signal transduction Molecular Genetics and Metabolism. 71: 293-314. PMID 11001823 DOI: 10.1006/mgme.2000.3068  1
2000 Dominici FP, Arostegui Diaz G, Bartke A, Kopchick JJ, Turyn D. Compensatory alterations of insulin signal transduction in liver of growth hormone receptor knockout mice. The Journal of Endocrinology. 166: 579-90. PMID 10974652  1
2000 Coschigano KT, Clemmons D, Bellush LL, Kopchick JJ. Assessment of growth parameters and life span of GHR/BP gene-disrupted mice Endocrinology. 141: 2608-2613. PMID 10875265 DOI: 10.1210/en.141.7.2608  1
2000 Leonard AE, Kelder B, Bobik EG, Chuang LT, Parker-Barnes JM, Thurmond JM, Kroeger PE, Kopchick JJ, Huang YS, Mukerji P. cDNA cloning and characterization of human Delta5-desaturase involved in the biosynthesis of arachidonic acid. The Biochemical Journal. 347: 719-24. PMID 10769175 DOI: 10.1042/0264-6021:3470719  1
2000 Asa SL, Coschigano KT, Bellush L, Kopchick JJ, Ezzat S. Evidence for growth hormone (GH) autoregulation in pituitary somatotrophs in GH antagonist-Transgenic mice and GH receptor-deficient mice American Journal of Pathology. 156: 1009-1015. PMID 10702416  1
2000 Bellush LL, Doublier S, Holland AN, Striker LJ, Striker GE, Kopchick JJ. Protection against diabetes-induced nephropathy in growth hormone receptor/binding protein gene-disrupted mice Endocrinology. 141: 163-168. PMID 10614635 DOI: 10.1210/en.141.1.163  1
1999 Bartke A, Chandrashekar V, Turyn D, Steger RW, Debeljuk L, Winters TA, Mattison JA, Danilovich NA, Croson W, Wernsing DR, Kopchick JJ. Effects of growth hormone overexpression and growth hormone resistance on neuroendocrine and reproductive functions in transgenic and knock-out mice. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 222: 113-23. PMID 10564535 DOI: 10.1046/j.1525-1373.1999.d01-121.x  0.56
1999 Zhang Y, Jiang J, Kopchick JJ, Frank SJ. Disulfide linkage of growth hormone (GH) receptors (GHR) reflects GH- induced GHR dimerization. Association of JAK2 with the GHR is enhanced by receptor dimerization Journal of Biological Chemistry. 274: 33072-33084. PMID 10551877 DOI: 10.1074/jbc.274.46.33072  1
1999 Kopchick JJ, Laron Z. Is the Laron mouse an accurate model of Laron syndrome? Molecular Genetics and Metabolism. 68: 232-236. PMID 10527674 DOI: 10.1006/mgme.1999.2890  1
1999 Kopchick JJ, Bellush LL, Coschigano KT. Transgenic models of growth hormone action Annual Review of Nutrition. 19: 437-461. PMID 10448532 DOI: 10.1146/annurev.nutr.19.1.437  1
1999 Goffin V, Bernichtein S, Carrière O, Bennett WF, Kopchick JJ, Kelly PA. The human growth hormone antagonist B2036 does not interact with the prolactin receptor Endocrinology. 140: 3853-3856. PMID 10433247  1
1999 Haldankar R, Kopchick JJ, Ridgway D. Stable production of a human growth hormone antagonist from CHO cells adapted to serum-free suspension culture Biotechnology Progress. 15: 336-346. PMID 10356250 DOI: 10.1021/bp9900460  1
1999 Danilovich N, Wernsing D, Coschigano KT, Kopchick JJ, Bartke A. Deficits in female reproductive function in GH-R-KO mice; role of IGF-I. Endocrinology. 140: 2637-40. PMID 10342852 DOI: 10.1210/endo.140.6.6992  1
1999 Flyvbjerg A, Bennett WF, Rasch R, Kopchick JJ, Scarlett JA. Inhibitory effect of a growth hormone receptor antagonist (G120K-PEG) on renal enlargement, glomerular hypertrophy, and urinary albumin excretion in experimental diabetes in mice Diabetes. 48: 377-382. PMID 10334317 DOI: 10.2337/diabetes.48.2.377  1
1999 Ruan W, Powell-Braxton L, Kopchick JJ, Kleinberg DL. Evidence that insulin-like growth factor I and growth hormone are required for prostate gland development Endocrinology. 140: 1984-1989. PMID 10218945  1
1999 Chandrashekar V, Bartke A, Coschigano KT, Kopchick JJ. Pituitary and testicular function in growth hormone receptor gene knockout mice. Endocrinology. 140: 1082-8. PMID 10067829 DOI: 10.1210/endo.140.3.6557  1
1999 Prieto PA, Kopchick JJ, Kelder B. Transgenic animals and nutrition research Journal of Nutritional Biochemistry. 10: 682-695. DOI: 10.1016/S0955-2863(99)00063-7  1
1998 Cheriathundam E, Doi SQ, Knapp JR, Jasser MZ, Kopchick JJ, Alvares AP. Consequences of overexpression of growth hormone in transgenic mice on liver cytochrome P450 enzymes Biochemical Pharmacology. 55: 1481-1487. PMID 10076541 DOI: 10.1016/S0006-2952(97)00667-9  1
1998 Sotelo AI, Bartke A, Kopchick JJ, Knapp JR, Turyn D. Growth hormone (GH) receptors, binding proteins and IGF-I concentrations in the serum of transgenic mice expressing bovine GH agonist or antagonist. The Journal of Endocrinology. 158: 53-9. PMID 9713326 DOI: 10.1677/joe.0.1580053  1
1998 Kopchick J, Chen XZ, Li Y, Steger RW, Yun JS, Wagner TE, Bartke A. Differential in vivo activities of bovine growth hormone analogues. Transgenic Research. 7: 61-71. PMID 9556914  0.76
1998 Turner ND, Knapp JR, Byers FM, Kopchick JJ. Expression of mutant bovine growth hormone genes in mice perturbs age- related nutrient utilization patterns Journal of Nutrition. 128: 520-524. PMID 9482758  1
1997 Kelder B, Richmond C, Stavnezer E, List EO, Kopchick JJ. Production, characterization and functional activities of v-Ski in cultured cells Gene. 202: 15-21. PMID 9427540 DOI: 10.1016/S0378-1119(97)00439-3  1
1997 Zhou Y, Xu BC, Maheshwari HG, He L, Reed M, Lozykowski M, Okada S, Cataldo L, Coschigamo K, Wagner TE, Baumann G, Kopchick JJ. A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse). Proceedings of the National Academy of Sciences of the United States of America. 94: 13215-20. PMID 9371826 DOI: 10.1073/pnas.94.24.13215  0.76
1997 Zhou Y, He L, Baumann G, Kopchick JJ. Deletion of the mouse GH-binding protein (mGHBP) mRNA polyadenylation and splicing sites does not abolish production of mGHBP Journal of Molecular Endocrinology. 19: 1-13. PMID 9278856  1
1997 Thurmond JM, Hards RG, Seipelt CT, Leonard AE, Hansson L, Strömqvist M, Byström M, Enquist K, Xu BC, Kopchick JJ, Mukerji P. Expression and characterization of phosphorylated recombinant human beta-casein in Escherichia coli. Protein Expression and Purification. 10: 202-8. PMID 9226716 DOI: 10.1006/prep.1997.0737  1
1997 Smith LE, Kopchick JJ, Chen W, Knapp J, Kinose F, Daley D, Foley E, Smith RG, Schaeffer JM. Essential role of growth hormone in ischemia-induced retinal neovascularization. Science (New York, N.Y.). 276: 1706-9. PMID 9180082 DOI: 10.1126/science.276.5319.1706  1
1997 Chen NY, Chen WY, Kopchick JJ. Liver and kidney growth hormone (GH) receptors are regulated differently in diabetic GH and GH antagonist transgenic mice Endocrinology. 138: 1988-1994. PMID 9112397  1
1997 Yang CW, Striker GE, Chen WY, Kopchick JJ, Striker LJ. Differential expression of glomerular extracellular matrix and growth factor mRNA in rapid and slowly progressive glomerulosclerosis: Studies in mice transgenic for native or mutated growth hormone Laboratory Investigation. 76: 467-476. PMID 9111509  1
1997 Chen NY, Chen WY, Striker LJ, Striker GE, Kopchick JJ. Co-expression of bovine growth hormone (GH) and human GH antagonist genes in transgenic mice Endocrinology. 138: 851-854. PMID 9003027 DOI: 10.1210/en.138.2.851  1
1997 Kopchick JJ, Woodley FW. Chapter 3 Regulation of growth hormone gene expression Advances in Molecular and Cellular Endocrinology. 1: 51-82. DOI: 10.1016/S1569-2566(97)80034-8  1
1996 Wang X, Darus CJ, Xu BC, Kopchick JJ. Identification of growth hormone receptor (GHR) tyrosine residues required for GHR phosphorylation and JAK2 and STAT5 activation Molecular Endocrinology. 10: 1249-1260. PMID 9121492 DOI: 10.1210/me.10.10.1249  1
1996 Zhou Y, He L, Kopchick JJ. Structural comparison of a portion of the rat and mouse growth hormone receptor/binding protein genes Gene. 177: 257-259. PMID 8921876 DOI: 10.1016/0378-1119(96)00277-6  1
1996 Chen NY, Chen WY, Kopchick JJ. A growth hormone antagonist protects mice against streptozotocin induced glomerulosclerosis even in the presence of elevated levels of glucose and glycated hemoglobin Endocrinology. 137: 5163-5165. PMID 8895392 DOI: 10.1210/en.137.11.5163  1
1996 Bellush LL, Wright AM, Walker JP, Kopchick J, Colvin RA. Caloric restriction and spatial learning in old mice. Physiology & Behavior. 60: 541-7. PMID 8840916 DOI: 10.1016/S0031-9384(96)80029-1  1
1996 Xu BC, Wang X, Darus CJ, Kopchick JJ. Growth hormone promotes the association of transcription factor STAT5 with the growth hormone receptor Journal of Biological Chemistry. 271: 19768-19773. PMID 8702683 DOI: 10.1074/jbc.271.33.19768  1
1996 Harding PA, Wang X, Okada S, Chen WY, Wan W, Kopchick JJ. Growth hormone (GH) and a GH antagonist promote GH receptor dimerization and internalization Journal of Biological Chemistry. 271: 6708-6712. PMID 8636090 DOI: 10.1074/jbc.271.12.6708  1
1996 Tuck MT, James CB, Kelder B, Kopchick JJ. Elevation of internal 6-methyladenine mRNA methyltransferase activity after cellular transformation. Cancer Letters. 103: 107-13. PMID 8616802 DOI: 10.1016/0304-3835(96)04203-6  1
1996 Mode A, Tollet P, Wells T, Carmignac DF, Clark RG, Chen WY, Kopchick JJ, Robinson IC. The human growth hormone (hGH) antagonist G120RhGH does not antagonize GH in the rat, but has paradoxical agonist activity, probably via the prolactin receptor. Endocrinology. 137: 447-54. PMID 8593788 DOI: 10.1210/endo.137.2.8593788  0.4
1996 Turner ND, Bvers FM, Knapp JR, Kopchick JJ. Regulation of bone characteristics by altered body composition in bGH transgenic mice Faseb Journal. 10.  1
1996 Mehta BV, Mehta SB, Rabelo LC, Kopchick JJ. Artificial intelligence techniques for analyzing the 3-D structure of proteins: Designing new proteins Biomedical Engineering - Applications, Basis and Communications. 8: 556-565.  1
1995 Hikida RS, Knapp JR, Chen WY, Gozdanovic JA, Kopchick JJ. Effects of bovine growth hormone analogs on mouse skeletal muscle structure Growth, Development and Aging. 59: 121-128. PMID 8675366  1
1995 Souza SC, Frick GP, Wang X, Kopchick JJ, Lobo RB, Goodman HM. A single arginine residue determines species specificity of the human growth hormone receptor. Proceedings of the National Academy of Sciences of the United States of America. 92: 959-63. PMID 7862673 DOI: 10.1073/pnas.92.4.959  1
1995 Chen NY, Chen WY, Bellush L, Yang CW, Striker LJ, Striker GE, Kopchick JJ. Effects of streptozotocin treatment in growth hormone (GH) and GH antagonist transgenic mice Endocrinology. 136: 660-667. PMID 7835300  1
1995 Dattani MT, Hindmarsh PC, Brook CGD, Robinson ICAF, Kopchick JJ, Marshall NJ. G120R, a human growth hormone antagonist, shows zinc-dependent agonist and antagonist activity on Nb2 cells Journal of Biological Chemistry. 270: 9222-9226. PMID 7721840 DOI: 10.1074/jbc.270.16.9222  1
1995 Harding PA, Wang XZ, Kopchick JJ. Growth hormone (GH)-induced tyrosine-phosphorylated proteins in cells that express GH receptors Receptor. 5: 81-92. PMID 7580939  1
1995 Xu BC, Wang X, James C, Kopchick JJ. Characterization of growth hormone-induced tyrosine-phosphorylated proteins in mouse cells that express GH receptors Receptor. 5: 105-116. PMID 7580936  1
1995 Xu BC, Chen WY, Gu T, Ridgway D, Wiehl P, Okada S, Kopchick JJ. Effects of growth hormone antagonists on 3T3-F442A preadipocyte differentiation Journal of Endocrinology. 146: 131-139. PMID 7561609  1
1995 Hou YT, Coleman TA, Kopchick JJ. AP-4- and AP-5-like proteins from mouse L cells are trans-activators and bind to the GT-II region of SV40 early TRE in a mutually exclusive manner Gene. 162: 197-203. PMID 7557429  1
1995 Chen WY, Chen NY, Yun J, Wight DC, Wang XZ, Wagner TE, Kopchick JJ. Amino acid residues in the third α-helix of growth hormone involved in growth promoting activity Molecular Endocrinology. 9: 292-302. PMID 7539887  1
1995 Wang X, Souza SC, Kelder B, Cioffi JA, Kopchick JJ. A 40-amino acid segment of the growth hormone receptor cytoplasmic domain is essential for GH-induced tyrosine-phosphorylated cytosolic proteins Journal of Biological Chemistry. 270: 6261-6266. PMID 7534308 DOI: 10.1074/jbc.270.11.6261  1
1995 Prieto PA, Mukerji P, Kelder B, Erney R, Gonzalez D, Yun JS, Smith DF, Moremen KW, Nardelli C, Pierce M. Remodeling of mouse milk glycoconjugates by transgenic expression of a human glycosyltransferase. The Journal of Biological Chemistry. 270: 29515-9. PMID 7493992 DOI: 10.1074/jbc.270.49.29515  1
1995 Liu ZH, Striker LJ, Phillips C, Chen NY, Chen WY, Kopchick JJ, Striker GE. Growth hormone expression is required for the development of diabetic glomerulosclerosis in mice Kidney International, Supplement. PMID 7474687  1
1994 Jura J, Kopchick JJ, Chen WY, Wagner TE, Modlinski JA, Reed MA, Knapp JR, Smorag Z. In vitro and in vivo development of bovine embryos from zygotes and 2-cell embryos microinjected with exogenous DNA. Theriogenology. 41: 1259-66. PMID 16727479 DOI: 10.1016/0093-691X(94)90483-Y  0.4
1994 Chen WY, Chen NY, Yun J, Wagner TE, Kopchick JJ. In vitro and in vivo studies of antagonistic effects of human growth hormone analogs Journal of Biological Chemistry. 269: 15892-15897. PMID 8195244  1
1994 Knapp JR, Kopchick JJ. The use of transgenic mice in nutrition research Journal of Nutrition. 124: 461-468. PMID 8145066  1
1994 Giraldi FP, Mizobuchi M, Horowitz ZD, Downs TR, Aleppo G, Kier A, Wagner T, Yun JS, Kopchick JJ, Frohman LA. Development of neuroepithelial tumors of the adrenal medulla in transgenic mice expressing a mouse hypothalamic growth hormone-releasing hormone promoter-simian virus-40 T-antigen fusion gene Endocrinology. 134: 1219-1224. PMID 8119162 DOI: 10.1210/endo.134.3.8119162  1
1994 Chiu PY, Chaudhuri S, Harding PA, Kopchick JJ, Donkin S, Etherton TD. Cloning of a pig glucose transporter 4 cDNA fragment: use in developing a sensitive ribonuclease protection assay for quantifying low-abundance glucose transporter 4 mRNA in porcine adipose tissue Journal of Animal Science. 72: 1196-1203. PMID 8056664  1
1994 Chen WY, Chen N, Yun J, Wagner TE, Kopchick JJ. In vitro and in vivo studies of the antagonistic effects of human growth hormone analogs Journal of Biological Chemistry. 269: 20806. PMID 8051183  1
1994 Cui C, Wani MA, Wight D, Kopchick J, Stambrook PJ. Reporter genes in transgenic mice Transgenic Research. 3: 182-194. PMID 8025596 DOI: 10.1007/BF01973986  1
1994 Harding PA, Wang XZ, Kelder B, Souza S, Okada S, Kopchick JJ. In vitro mutagenesis of growth hormone receptor Asn-linked glycosylation sites Molecular and Cellular Endocrinology. 106: 171-180. PMID 7895905 DOI: 10.1016/0303-7207(94)90200-3  1
1994 Zhou Y, He L, Kopchick JJ. An exon encoding the mouse growth hormone binding protein (mGHBP) carboxy terminus is located between exon 7 and 8 of the mouse growth hormone receptor gene Receptor. 4: 223-227. PMID 7894338  1
1994 Knapp JR, Chen WY, Turner ND, Byers FM, Kopchick JJ. Growth patterns and body composition of transgenic mice expressing mutated bovine somatotropin genes Journal of Animal Science. 72: 2812-2819. PMID 7730173  1
1994 Zhou Y, Xu B, Wang X, Chen WY, Kopchick JJ. Functional expression of a mouse growth hormone receptor cDNA in transfected mouse L cells Receptor. 4: 143-155. PMID 7529079  1
1994 Wang X, Xu B, Souza SC, Kopchick JJ. Growth hormone (GH) induces tyrosine-phosphorylated proteins in mouse L cells that express recombinant GH receptors Proceedings of the National Academy of Sciences of the United States of America. 91: 1391-1395. PMID 7509070  1
1994 Gu T, Gu Y, Zheng Y, Wiehl PE, Kopchick JJ. Phase separation of acetonitrile-water mixture in protein purification Separations Technology. 4: 258-260. DOI: 10.1016/0956-9618(94)80031-6  1
1993 Campbell RM, Chen WY, Wiehl P, Kelder B, Kopchick JJ, Scanes CG. A growth hormone (GH) analog that antagonizes the lipolytic effect but retains full insulin-like (antilipolytic) activity of GH Proceedings of the Society For Experimental Biology and Medicine. 203: 311-316. PMID 8516343  1
1993 Yang CW, Striker LJ, Kopchick JJ, Chen WY, Pesce CM, Peten EP, Striker GE. Glomerulosclerosis in mice transgenic for native or mutated bovine growth hormone gene Kidney International, Supplement. 39. PMID 8468934  1
1993 Wang X, Cioffi JA, Kelder B, Harding PA, Chen WY, Kopchick JJ. Expression of a functional porcine growth hormone receptor cDNA in mouse L cells Molecular and Cellular Endocrinology. 94: 89-96. PMID 8375578 DOI: 10.1016/0303-7207(93)90055-O  1
1993 Belecky-Adams T, Wight DC, Kopchick JJ, Parysek LM. Intragenic sequences are required for cell type-specific and injury-induced expression of the rat peripherin gene Journal of Neuroscience. 13: 5056-5065. PMID 8254361  1
1993 Eisen EJ, Fortman M, Chen WY, Kopchick JJ. Effect of genetic background on growth of mice hemizygous for wild-type or dwarf mutated bovine growth hormone transgenes Theoretical and Applied Genetics: International Journal of Plant Breeding Research. 87: 161-169. DOI: 10.1007/BF00223760  1
1992 Chen XZ, Shafer AW, Yun JS, Li YS, Wagner TE, Kopchick JJ. Conversion of bovine growth hormone cysteine residues to serine affects secretion by cultured cells and growth rates in transgenic mice. Molecular Endocrinology (Baltimore, Md.). 6: 598-606. PMID 1584223 DOI: 10.1210/mend.6.4.1584223  1
1992 Okada S, Chen WY, Wiehl P, Kelder B, Goodman HM, Guller S, Sonenberg M, Kopchick JJ. A growth hormone (GH) analog can antagonize the ability of native GH to promote differentiation of 3T3-F442A preadipocytes and stimulate insulin-like and lipolytic activities in primary rat adipocytes. Endocrinology. 130: 2284-90. PMID 1547740 DOI: 10.1210/endo.130.4.1547740  1
1992 Kopchick JJ. Biotechnology and food safety Journal of the American Veterinary Medical Association. 201: 228-234. PMID 1500314  1
1992 Coleman TA, Hou YT, Kopchick JJ. The SV40 early transcriptional regulatory element is unable to direct gene expression in pituitary GH-3 cells Gene Expression. 2: 175-189. PMID 1321682  1
1991 Coleman TA, Chomczynski P, Frohman LA, Kopchick JJ. A comparison of transcriptional regulatory element activities in transformed and non-transformed rat anterior pituitary cells Molecular and Cellular Endocrinology. 75: 91-100. PMID 2050277 DOI: 10.1016/0303-7207(91)90223-F  1
1991 Chen WY, White ME, Wagner TE, Kopchick JJ. Functional antagonism between endogenous mouse growth hormone (GH) and a GH analog results in dwarf transgenic mice. Endocrinology. 129: 1402-8. PMID 1874179 DOI: 10.1210/endo-129-3-1402  1
1991 Me Andrew SJ, Chen NY, Kelder B, Cioffi JA, Kopchick JJ. Effects of a leucine analog on growth hormone processing and secretion by cultured cells Journal of Biological Chemistry. 266: 15016-15020. PMID 1869539  1
1991 Chen WY, Wight DC, Mehta BV, Wagner TE, Kopchick JJ. Glycine 119 of bovine growth hormone is critical for growth-promoting activity. Molecular Endocrinology (Baltimore, Md.). 5: 1845-52. PMID 1791834 DOI: 10.1210/mend-5-12-1845  1
1991 Coleman TA, Hou Yt, Kopchick JJ. Importance of SV40 early 5′ distal sequences in directing heterologous gene expression Gene. 106: 243-248. PMID 1657724 DOI: 10.1016/0378-1119(91)90205-P  1
1991 Kopchick JJ, Cioffi JA. Exogenous and endogenous effects of growth hormone in animals Livestock Production Science. 27: 61-75. DOI: 10.1016/0301-6226(91)90046-S  1
1990 Chen WY, Wight DC, Wagner TE, Kopchick JJ. Expression of a mutated bovine growth hormone gene suppresses growth of transgenic mice Proceedings of the National Academy of Sciences of the United States of America. 87: 5061-5065. PMID 2367524  1
1990 Cioffi JA, Wang X, Kopchick JJ. Porcine growth hormone receptor cDNA sequence Nucleic Acids Research. 18: 6451. PMID 2243805 DOI: 10.1093/nar/18.21.6451  1
1990 Kopchick JJ, McAndrew SJ, Shafer A, Blue WT, Yun JS, Wagner TE, Chen WY. In-vitro mutagenesis of the bovine growth hormone gene Journal of Reproduction and Fertility. Supplement. 41: 25-35. PMID 2213712  1
1990 Chen HY, Garber EA, Mills E, Smith J, Kopchick JJ, DiLella AG, Smith RG. Vectors, promoters, and expression of genes in chick embryos Journal of Reproduction and Fertility. Supplement. 41: 173-182. PMID 2170640  1
1990 Brar AK, Coleman TA, Kopchick JJ, Frohman LA. Expression of a cytomegalovirus-human growth hormone-releasing hormone precursor fusion gene in transfected GH3 cells Molecular and Cellular Endocrinology. 71: 105-115. PMID 2165457 DOI: 10.1016/0303-7207(90)90247-6  1
1990 Fernández E, Kopchick JJ. Quantitative determination of growth hormone by immunoblotting Analytical Biochemistry. 191: 268-271. PMID 2085173 DOI: 10.1016/0003-2697(90)90218-X  1
1989 Kelder B, Chen H, Kopchick JJ. Activation of the mouse metallothionein-I promoter in transiently transfected avian cells Gene. 76: 75-80. PMID 2744481 DOI: 10.1016/0378-1119(89)90009-7  1
1988 Cascieri MA, Hayes NS, Kelder B, Kopchick JJ, Chicchi GG, Slater EE, Bayne ML. Inability of a mouse cell line transformed to produce biologically active recombinant human insulin-like growth factor I (IGF-I) to respond to exogenously added IGF-I. Endocrinology. 122: 1314-20. PMID 2964361 DOI: 10.1210/endo-122-4-1314  1
1987 Pasleau F, Leung F, Kopchick JJ. A comparison of bovine growth hormone expression directed by bGH genomic or intronless DNA in transiently transfected eukaryotic cells Gene. 57: 47-52. PMID 2828181 DOI: 10.1016/0378-1119(87)90175-2  1
1987 Gorewit RC, Chen HY, Kopchick JJ. Growth hormone gene expression in myoepithelial cells directed by various eucaryotic transcriptional regulatory sequences Febs Letters. 225: 238-242. PMID 2826241 DOI: 10.1016/0014-5793(87)81165-1  1
1986 Stacey DW, Kopchick JJ, Kahn M. The effects of transcriptional regulatory sequences introduced into a retroviral genome Dna (Mary Ann Liebert, Inc.). 5: 195-202. PMID 3013546  1
1986 Kopchick JJ, Pasleau F, Leung FC. Expression of the bovine growth hormone gene in cultured rodent cells Basic Life Sciences. 37: 19-37. PMID 3010933  1
1985 Burch WM, Corda G, Kopchick JJ, Leung FC. Homologous and heterologous growth hormones fail to stimulate avian cartilage growth in vitro Journal of Clinical Endocrinology and Metabolism. 60: 747-750. PMID 4038715  1
1985 Pasleau F, Tocci MJ, Leung F, Kopchick JJ. Growth hormone gene expression in eukaryotic cells directed by the Rous sarcoma virus long terminal repeat or cytomegalovirus immediate-early promoter Gene. 38: 227-232. PMID 2998944 DOI: 10.1016/0378-1119(85)90221-5  1
1985 Kopchick JJ, Malavarca RH, Livelli TJ, Leung FC. Use of avian retroviral-bovine growth hormone DNA recombinants to direct expression of biologically active growth hormone by cultured fibroblasts Dna. 4: 23-31. PMID 2982557  1
1985 Pasleau F, Tocci MJ, Leung FC, Kopchick JJ. Growth hormone gene expression in eucaryotic cells directed by the Rous aSrcoma viral long terminal repeat or cytomegalovirus immediate early promoter-regulator Federation Proceedings. 44.  1
1985 Leung FC, Jones B, Steelman l. S, Kopchick JJ. Purified recombinant bovine growth hormone from cultured fibroblasts is biologically active Federation Proceedings. 44.  1
1984 Chinsky J, Soeiro R, Kopchick J. Fv-1 host cell restriction of friend leukemia virus: microinjection of unintegrated viral DNA. Journal of Virology. 50: 271-4. PMID 6699946  1
1984 Kopchick JJ, Stacey DW. Differences in intracellular DNA ligation after microinjection and transfection Molecular and Cellular Biology. 4: 240-246. PMID 6321956  1
1983 Thornton GB, Kopchick JJ, Stacey DW, Banerjee AK. Microinjection of vesicular stomatitis virus ribonucleoprotein into animal cells yields infectious virus Biochemical and Biophysical Research Communications. 116: 1160-1167. PMID 6316970 DOI: 10.1016/S0006-291X(83)80264-2  1
1983 Kopchick JJ, Stacey DW. Selective ligation of DNA molecules following microinjection Journal of Biological Chemistry. 258: 11528-11536. PMID 6311814  1
1982 Cullen BR, Kopchick JJ, Stacey DW. Effect of intron size on splicing efficiency in retroviral transcripts Nucleic Acids Research. 10: 6177-6190. PMID 6292870 DOI: 10.1093/nar/10.19.6177  1
1981 Kopchick JJ, Cullen BR, Stacey DW. Rapid analysis of small nucleic acid samples by gel electrophoresis Analytical Biochemistry. 115: 419-423. PMID 6272606 DOI: 10.1016/0003-2697(81)90027-0  1
1981 Kopchick JJ, Ju G, Skalka AM, Stacey DW. Biological activity of cloned retroviral DNA in microinjected cells Proceedings of the National Academy of Sciences of the United States of America. 78: 4383-4387. PMID 6270676  1
1981 Kopchick JJ, Harless J, Geisser BS, Killam R, Hewitt RR, Arlinghaus RB. Endodeoxyribonuclease activity associated with Rauscher murine leukemia virus Journal of Virology. 37: 274-283. PMID 6260982  1
1980 Ng VL, Kopchick JJ, Karshin WL, Wood TG, Arlinghaus RB. The structural relatedness of the virus core proteins on Rauscher and Moloney murine leukaemia virus Journal of General Virology. 47: 161-170. PMID 7365462  1
1979 Kopchick JJ, Karshin WL, Arlinghaus RB. Tryptic peptide analysis of gag and gag-pol gene products of Rauscher murine leukemia virus Journal of Virology. 30: 610-623. PMID 469995  1
1979 Kopchick JJ, Hartline RA. alpha-Hydroxyglutarate as an intermediate in the catabolism of alpha-aminoadipate by Pseudomonas putida Journal of Biological Chemistry. 254: 3259-3263. PMID 429347  1
1978 Kopchick JJ, Jamjoom GA, Watson KF, Arlinghaus RB. Biosynthesis of reverse transcriptase from Rauscher murine leukemia virus by synthesis and cleavage of a gag-pol read-through viral precursor polyprotein Proceedings of the National Academy of Sciences of the United States of America. 75: 2016-2020. PMID 77022  1
1978 Murphy EC, Kopchick JJ, Watson KF, Arlinghaus RB. Cell-free synthesis of a precursor polyprotein containing both gag and pol gene products by Rauscher murine leukemia virus 35S RNA Cell. 13: 359-369. PMID 75071 DOI: 10.1016/0092-8674(78)90204-0  1
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