Year |
Citation |
Score |
2011 |
Zhang F, Lowe ER, Rick DL, Qiu X, Leibold E, Cruzan G, Bartels MJ. In vitro metabolism, glutathione conjugation, and CYP isoform specificity of epoxidation of 4-vinylphenol. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 41: 6-23. PMID 20925585 DOI: 10.3109/00498254.2010.523735 |
0.339 |
|
2004 |
Yu L, Liu H, Li W, Zhang F, Luckie C, van Breemen RB, Thatcher GR, Bolton JL. Oxidation of raloxifene to quinoids: potential toxic pathways via a diquinone methide and o-quinones. Chemical Research in Toxicology. 17: 879-88. PMID 15257612 DOI: 10.1021/Tx0342722 |
0.69 |
|
2003 |
Liu X, Zhang F, Liu H, Burdette JE, Li Y, Overk CR, Pisha E, Yao J, van Breemen RB, Swanson SM, Bolton JL. Effect of halogenated substituents on the metabolism and estrogenic effects of the equine estrogen, equilenin. Chemical Research in Toxicology. 16: 741-9. PMID 12807357 DOI: 10.1021/Tx030001F |
0.728 |
|
2003 |
Johnson BM, Qiu SX, Zhang S, Zhang F, Burdette JE, Yu L, Bolton JL, van Breemen RB. Identification of novel electrophilic metabolites of piper methysticum Forst (Kava). Chemical Research in Toxicology. 16: 733-40. PMID 12807356 DOI: 10.1021/Tx020113R |
0.683 |
|
2001 |
Zhang F, Swanson SM, van Breemen RB, Liu X, Yang Y, Gu C, Bolton JL. Equine estrogen metabolite 4-hydroxyequilenin induces DNA damage in the rat mammary tissues: formation of single-strand breaks, apurinic sites, stable adducts, and oxidized bases. Chemical Research in Toxicology. 14: 1654-9. PMID 11743748 DOI: 10.1021/Tx010158C |
0.697 |
|
2001 |
Yao D, Zhang F, Yu L, Yang Y, van Breemen RB, Bolton JL. Synthesis and reactivity of potential toxic metabolites of tamoxifen analogues: droloxifene and toremifene o-quinones. Chemical Research in Toxicology. 14: 1643-53. PMID 11743747 DOI: 10.1021/Tx010137I |
0.69 |
|
2001 |
Zhang F, Yao D, Hua Y, van Breemen RB, Bolton JL. Synthesis and reactivity of the catechol metabolites from the equine estrogen, 8,9-dehydroestrone. Chemical Research in Toxicology. 14: 754-63. PMID 11409947 DOI: 10.1021/Tx010049Y |
0.717 |
|
2001 |
Spink DC, Zhang F, Hussain MM, Katz BH, Liu X, Hilker DR, Bolton JL. Metabolism of equilenin in MCF-7 and MDA-MB-231 human breast cancer cells. Chemical Research in Toxicology. 14: 572-81. PMID 11368557 DOI: 10.1021/Tx000219R |
0.634 |
|
2001 |
Hua Y, Wainhaus SB, Yang Y, Shen L, Xiong Y, Xu X, Zhang F, Bolton JL, van Breemen RB. Comparison of negative and positive ion electrospray tandem mass spectrometry for the liquid chromatography tandem mass spectrometry analysis of oxidized deoxynucleosides. Journal of the American Society For Mass Spectrometry. 12: 80-7. PMID 11142363 DOI: 10.1016/S1044-0305(00)00191-4 |
0.562 |
|
2000 |
Chen Y, Liu X, Pisha E, Constantinou AI, Hua Y, Shen L, van Breemen RB, Elguindi EC, Blond SY, Zhang F, Bolton JL. A metabolite of equine estrogens, 4-hydroxyequilenin, induces DNA damage and apoptosis in breast cancer cell lines. Chemical Research in Toxicology. 13: 342-50. PMID 10813650 DOI: 10.1021/Tx990186J |
0.688 |
|
2000 |
Zhang F, Fan PW, Liu X, Shen L, van Breemen RB, Bolton JL. Synthesis and reactivity of a potential carcinogenic metabolite of tamoxifen: 3,4-dihydroxytamoxifen-o-quinone. Chemical Research in Toxicology. 13: 53-62. PMID 10649967 DOI: 10.1021/Tx990145N |
0.763 |
|
2000 |
Fan PW, Zhang F, Bolton JL. 4-Hydroxylated metabolites of the antiestrogens tamoxifen and toremifene are metabolized to unusually stable quinone methides. Chemical Research in Toxicology. 13: 45-52. PMID 10649966 DOI: 10.1021/Tx990144V |
0.748 |
|
1999 |
Zhang F, Chen Y, Pisha E, Shen L, Xiong Y, van Breemen RB, Bolton JL. The major metabolite of equilin, 4-hydroxyequilin, autoxidizes to an o-quinone which isomerizes to the potent cytotoxin 4-hydroxyequilenin-o-quinone. Chemical Research in Toxicology. 12: 204-13. PMID 10027800 DOI: 10.1021/Tx980217V |
0.734 |
|
1999 |
Zhang F, Bolton JL. Synthesis of the equine estrogen metabolites 2-hydroxyequilin and 2-hydroxyequilenin. Chemical Research in Toxicology. 12: 200-3. PMID 10027799 DOI: 10.1021/Tx980189G |
0.669 |
|
1998 |
Bolton JL, Pisha E, Zhang F, Qiu S. Role of quinoids in estrogen carcinogenesis. Chemical Research in Toxicology. 11: 1113-27. PMID 9778307 DOI: 10.1021/Tx9801007 |
0.557 |
|
1998 |
Chen Y, Shen L, Zhang F, Lau SS, van Breemen RB, Nikolic D, Bolton JL. The equine estrogen metabolite 4-hydroxyequilenin causes DNA single-strand breaks and oxidation of DNA bases in vitro. Chemical Research in Toxicology. 11: 1105-11. PMID 9760286 DOI: 10.1021/Tx980083L |
0.617 |
|
1998 |
Chang M, Zhang F, Shen L, Pauss N, Alam I, van Breemen RB, Blond SY, Bolton JL. Inhibition of glutathione S-transferase activity by the quinoid metabolites of equine estrogens. Chemical Research in Toxicology. 11: 758-65. PMID 9671538 DOI: 10.1021/Tx9702190 |
0.74 |
|
1998 |
Shen L, Qiu S, Chen Y, Zhang F, van Breemen RB, Nikolic D, Bolton JL. Alkylation of 2'-deoxynucleosides and DNA by the Premarin metabolite 4-hydroxyequilenin semiquinone radical. Chemical Research in Toxicology. 11: 94-101. PMID 9511900 DOI: 10.1021/Tx970181R |
0.601 |
|
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