Donald A. Simone - Publications

Affiliations: 
Neuroscience University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Neuroscience Biology, Physiology Biology

130 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Banik RK, Sia T, Ibrahim MM, Sivanesan E, Uhelski M, Pena A, Streicher JM, Simone DA. Increases in local skin temperature correlate with spontaneous foot lifting and heat hyperalgesia in both incisional inflammatory models of pain. Pain Reports. 8: e1097. PMID 37711430 DOI: 10.1097/PR9.0000000000001097  0.34
2023 Rogness VM, Juliette J, Khasabova IA, Gupta K, Khasabov SG, Simone DA. Descending facilitation of nociceptive transmission from the rostral ventromedial medulla contributes to hyperalgesia in mice with sickle cell disease. Neuroscience. PMID 37330194 DOI: 10.1016/j.neuroscience.2023.06.007  0.307
2023 Khasabova IA, Khasabov SG, Johns M, Juliette J, Zheng A, Morgan H, Flippen A, Allen K, Golovko MY, Golovko SA, Zhang W, Marti J, Cain D, Seybold VS, Simone DA. Exosome-associated lysophosphatidic acid signaling contributes to cancer pain. Pain. PMID 37278638 DOI: 10.1097/j.pain.0000000000002967  0.371
2023 Cataldo G, Lunzer MM, Akgün E, Wong HL, Portoghese PS, Simone DA. MMG22 potently blocks hyperalgesia in cisplatin-treated mice. Neuroscience. PMID 36805004 DOI: 10.1016/j.neuroscience.2023.02.006  0.313
2021 Khasabova IA, Seybold VS, Simone DA. The role of PPARγ in chemotherapy-evoked pain. Neuroscience Letters. 135845. PMID 33774149 DOI: 10.1016/j.neulet.2021.135845  0.328
2021 Khasabov SG, Rogness VM, Beeson MB, Vulchanova-Hart L, Yuan LL, Simone DA, Tran PV. The nAChR chaperone TMEM35a (NACHO) contributes to the development of hyperalgesia in mice. Neuroscience. PMID 33422618 DOI: 10.1016/j.neuroscience.2020.12.027  0.388
2020 Tran PV, Johns ME, McAdams B, Abrahante JE, Simone DA, Banik RK. Global transcriptome analysis of rat dorsal root ganglia to identify molecular pathways involved in incisional pain. Molecular Pain. 16: 1744806920956480. PMID 32909881 DOI: 10.1177/1744806920956480  0.411
2020 Uhelski ML, Bruce D, Speltz R, Wilcox GL, Simone DA. Topical Application of Loperamide/Oxymorphindole, Mu and Delta Opioid Receptor Agonists, Reduces Sensitization of C-fiber Nociceptors that Possess Na1.8. Neuroscience. PMID 32858141 DOI: 10.1016/J.Neuroscience.2020.08.022  0.451
2020 Khasabova IA, Golovko MY, Golovko SA, Simone DA, Khasabov SG. Intrathecal Administration of Resolvin D1 and E1 Decreases Hyperalgesia in Mice with Bone Cancer Pain: Involvement of Endocannabinoid Signaling. Prostaglandins & Other Lipid Mediators. 106479. PMID 32745525 DOI: 10.1016/J.Prostaglandins.2020.106479  0.487
2020 Speltz R, Lunzer MM, Shueb SS, Akgün E, Reed R, Kalyuzhny A, Portoghese PS, Simone DA. The bivalent ligand, MMG22, reduces neuropathic pain after nerve injury without the side effects of traditional opioids. Pain. PMID 32345918 DOI: 10.1097/J.Pain.0000000000001902  0.498
2020 Khasabov SG, Truong H, Rogness VM, Alloway KD, Simone DA, Giesler GJ. Responses of neurons in the primary somatosensory cortex to itch- and pain-producing stimuli in rats. Journal of Neurophysiology. PMID 32292106 DOI: 10.1152/Jn.00038.2020  0.46
2020 Uhelski ML, McAdams B, Johns ME, Kabadi RA, Simone DA, Banik RK. Lack of relationship between epidermal denervation by capsaicin and incisional pain behaviours: A laser scanning confocal microscopy study in rats. European Journal of Pain (London, England). PMID 32219920 DOI: 10.1002/Ejp.1564  0.424
2019 Sheub SS, Erb SJ, Lunzer MM, Speltz R, Harding-Rose C, Akgün E, Simone DA, Portoghese PS. Targeting MOR-mGluR heteromers reduces bone cancer pain by activating MOR and inhibiting mGluR5. Neuropharmacology. 107690. PMID 31271770 DOI: 10.1016/J.Neuropharm.2019.107690  0.507
2019 Barney CC, Merbler AM, Simone DA, Walk D, Symons FJ. Investigating the Feasibility of a Modified Quantitative Sensory Testing Approach to Profile Sensory Function and Predict Pain Outcomes Following Intrathecal Baclofen Implant Surgery in Cerebral Palsy. Pain Medicine (Malden, Mass.). PMID 31268147 DOI: 10.1093/Pm/Pnz114  0.401
2019 Uhelski ML, Simone DA. Sensitization of Nociceptors and Dorsal Horn Neurons Contributes to Pain in Sickle Cell Disease. Neuroscience Letters. PMID 30995520 DOI: 10.1016/J.Neulet.2019.04.013  0.442
2019 Cataldo G, Erb SJ, Lunzer MM, Luong N, Akgün E, Portoghese PS, Olson JK, Simone DA. The bivalent ligand MCC22 potently attenuates hyperalgesia in a mouse model of cisplatin-evoked neuropathic pain without tolerance or reward. Neuropharmacology. PMID 30970233 DOI: 10.1016/J.Neuropharm.2019.04.004  0.511
2019 Khasabova IA, Uhelski M, Khasabov S, Gupta K, Seybold VS, Simone DA. Sensitization of nociceptors by prostaglandin E-glycerol contributes to hyperalgesia in mice with sickle cell disease. Blood. PMID 30796025 DOI: 10.1182/Blood-2018-11-884346  0.472
2018 Khasabova IA, Khasabov SG, Olson JK, Uhelski ML, Kim AH, Albino-Ramírez AM, Wagner CL, Seybold VS, Simone DA. Pioglitazone, a PPARγ agonist, reduces cisplatin-evoked neuropathic pain by protecting against oxidative stress. Pain. PMID 30507781 DOI: 10.1097/J.Pain.0000000000001448  0.495
2018 Lipshetz B, Khasabov SG, Truong H, Netoff TI, Simone DA, Giesler GJ. Responses of thalamic neurons to itch- and pain-producing stimuli in rats. Journal of Neurophysiology. PMID 29873617 DOI: 10.1152/Jn.00264.2018  0.454
2018 Kaliappan S, Simone DA, Banik RK. Nonlinear Inverted-U Shaped Relationship between Aging and Epidermal Innervation in the Rat Plantar Hind Paw: a Laser Scanning Confocal Microscopy Study. The Journal of Pain : Official Journal of the American Pain Society. PMID 29660414 DOI: 10.1016/J.Jpain.2018.04.002  0.357
2018 Cataldo G, Lunzer MM, Olson JK, Akgün E, Belcher JD, Vercellotti GM, Portoghese PS, Simone DA. The bivalent ligand MCC22 potently attenuates nociception in a murine model of sickle cell disease. Pain. PMID 29578946 DOI: 10.1097/J.Pain.0000000000001225  0.502
2018 Simone D, Gupta K. Prostaglandin E2 Glyceryl Ester Contributes to Hyperalgesia in a Humanized Model Pf Sickle Cell Disease through P2Y6 Receptors Blood. 132: 1075-1075. DOI: 10.1182/Blood-2018-99-118945  0.419
2018 Strichartz G, Khasabov S, Barr T, Wang J, Simone D. Modulation of chronic post-thoracotomy pain by NK-1 neurons in the rostral ventromedial medulla is not paralleled by changes spinal MAPKinase activation The Journal of Pain. 19: S14. DOI: 10.1016/J.Jpain.2017.12.065  0.448
2017 Khasabov SG, Malecha P, Noack J, Tabakov J, Giesler GJ, Simone DA. Hyperalgesia and sensitization of dorsal horn neurons following activation of NK-1 receptors in the rostral ventromedial medulla. Journal of Neurophysiology. jn.00478.2017. PMID 28794197 DOI: 10.1152/Jn.00478.2017  0.519
2017 Khasabov SG, Wang JC, Simone DA, Strichartz GR. A role for neurokinin-1 receptor neurons in the rostral ventromedial medulla in the development of chronic postthoracotomy pain. Pain. 158: 1332-1341. PMID 28622274 DOI: 10.1097/J.Pain.0000000000000919  0.512
2017 Uhelski ML, Gupta K, Simone DA. Sensitization of C-fiber nociceptors in mice with sickle cell disease is decreased by local inhibition of anandamide hydrolysis. Pain. PMID 28570479 DOI: 10.1097/J.Pain.0000000000000966  0.511
2017 Khasabov SG, Chi-Fei Wang J, Simone DA, Strichartz GR. A role for nk-1 neurons in the rostral ventromedial medulla in the development of chronic post-thoracotomy pain. Pain. PMID 28394854 DOI: 10.1097/j.pain.0000000000000919  0.393
2017 Uhelski ML, Bruce DJ, Seguela P, Wilcox GL, Simone DA. In vivo optogenetic activation of Nav1.8+ cutaneous nociceptors and their responses to natural stimuli. Journal of Neurophysiology. jn.00083.2017. PMID 28298301 DOI: 10.1152/Jn.00083.2017  0.397
2015 Matson DJ, Hamamoto DT, Bregman H, Cooke M, DiMauro EF, Huang L, Johnson D, Li X, McDermott J, Morgan C, Wilenkin B, Malmberg AB, McDonough SI, Simone DA. Inhibition of Inactive States of Tetrodotoxin-Sensitive Sodium Channels Reduces Spontaneous Firing of C-Fiber Nociceptors and Produces Analgesia in Formalin and Complete Freund's Adjuvant Models of Pain. Plos One. 10: e0138140. PMID 26379236 DOI: 10.1371/Journal.Pone.0138140  0.782
2015 Cataldo G, Rajput S, Gupta K, Simone DA. Sensitization of nociceptive spinal neurons contributes to pain in a transgenic model of sickle cell disease. Pain. 156: 722-30. PMID 25630029 DOI: 10.1097/J.Pain.0000000000000104  0.505
2015 Chizhmakov I, Kulyk V, Khasabova I, Khasabov S, Simone D, Bakalkin G, Gordienko D, Verkhratsky A, Krishtal O. Molecular mechanism for opioid dichotomy: bidirectional effect of μ-opioid receptors on P2X₃ receptor currents in rat sensory neurones. Purinergic Signalling. 11: 171-81. PMID 25592684 DOI: 10.1007/S11302-015-9443-X  0.389
2015 Uhelski ML, Khasabova IA, Simone DA. Inhibition of anandamide hydrolysis attenuates nociceptor sensitization in a murine model of chemotherapy-induced peripheral neuropathy. Journal of Neurophysiology. 113: 1501-10. PMID 25505113 DOI: 10.1152/Jn.00692.2014  0.531
2015 Khasabov SG, Malecha P, Noack J, Tabakov J, Okamoto K, Bereiter DA, Simone DA. Activation of rostral ventromedial medulla neurons by noxious stimulation of cutaneous and deep craniofacial tissues. Journal of Neurophysiology. 113: 14-22. PMID 25185804 DOI: 10.1152/Jn.00125.2014  0.431
2015 Cataldo G, Lunzer MM, Simone DA, Akgün E, Belcher JD, Vercellotti GM, Portoghese PS. Targeting Putative Mu Opioid/Chemokine Receptor Type 5 Heteromers Potently Attenuates Nociception in a Murine Model of Sickle Cell Disease Blood. 126: 277-277. DOI: 10.1182/Blood.V126.23.277.277  0.462
2015 Strichartz G, Wang J, Khasabov S, Kojima K, Simone D, Vacanti C. (285) Spinal cord-derived neural stem cells restore hyperalgesic responses previously diminished by chemical ablation of NK-1 expressing neurons in the rat spinal cord The Journal of Pain. 16: S47. DOI: 10.1016/J.Jpain.2015.01.203  0.323
2014 Khasabova IA, Yao X, Paz J, Lewandowski CT, Lindberg AE, Coicou L, Burlakova N, Simone DA, Seybold VS. JZL184 is anti-hyperalgesic in a murine model of cisplatin-induced peripheral neuropathy. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 90: 67-75. PMID 25304184 DOI: 10.1016/J.Phrs.2014.09.008  0.452
2014 de Carvalho Barbosa M, Kosturakis AK, Eng C, Wendelschafer-Crabb G, Kennedy WR, Simone DA, Wang XS, Cleeland CS, Dougherty PM. A quantitative sensory analysis of peripheral neuropathy in colorectal cancer and its exacerbation by oxaliplatin chemotherapy. Cancer Research. 74: 5955-62. PMID 25183707 DOI: 10.1158/0008-5472.Can-14-2060  0.344
2014 Paul J, Lei J, Jha R, Nguyen J, Simone DA, Gupta K. Heme Induced Spinal Microglial Cell Activation By TLR4 and Endoplasmic Reticulum Stress in Sickle Mice Blood. 124: 452-452. DOI: 10.1182/Blood.V124.21.452.452  0.404
2013 Khasabov SG, Simone DA. Loss of neurons in rostral ventromedial medulla that express neurokinin-1 receptors decreases the development of hyperalgesia Neuroscience. 250: 151-165. PMID 23831426 DOI: 10.1016/J.Neuroscience.2013.06.057  0.468
2013 Vincent L, Vang D, Nguyen J, Gupta M, Luk K, Ericson ME, Simone DA, Gupta K. Mast cell activation contributes to sickle cell pathobiology and pain in mice. Blood. 122: 1853-62. PMID 23775718 DOI: 10.1182/Blood-2013-04-498105  0.446
2013 Uhelski ML, Cain DM, Harding-Rose C, Simone DA. The non-selective cannabinoid receptor agonist WIN 55,212-2 attenuates responses of C-fiber nociceptors in a murine model of cancer pain. Neuroscience. 247: 84-94. PMID 23673278 DOI: 10.1016/J.Neuroscience.2013.05.003  0.549
2013 Khasabova IA, Holman M, Morse T, Burlakova N, Coicou L, Harding-Rose C, Simone DA, Seybold VS. Increased anandamide uptake by sensory neurons contributes to hyperalgesia in a model of cancer pain. Neurobiology of Disease. 58: 19-28. PMID 23644187 DOI: 10.1016/J.Nbd.2013.04.018  0.495
2012 Khasabov SG, Brink TS, Schupp M, Noack J, Simone DA. Changes in response properties of rostral ventromedial medulla neurons during prolonged inflammation: modulation by neurokinin-1 receptors. Neuroscience. 224: 235-48. PMID 22917610 DOI: 10.1016/J.Neuroscience.2012.08.029  0.47
2012 Davidson S, Zhang X, Khasabov SG, Moser HR, Honda CN, Simone DA, Giesler GJ. Pruriceptive spinothalamic tract neurons: physiological properties and projection targets in the primate. Journal of Neurophysiology. 108: 1711-23. PMID 22723676 DOI: 10.1152/Jn.00206.2012  0.381
2012 Khasabova IA, Khasabov S, Paz J, Harding-Rose C, Simone DA, Seybold VS. Cannabinoid type-1 receptor reduces pain and neurotoxicity produced by chemotherapy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 7091-101. PMID 22593077 DOI: 10.1523/Jneurosci.0403-12.2012  0.532
2012 Cain DM, Vang D, Simone DA, Hebbel RP, Gupta K. Mouse models for studying pain in sickle disease: effects of strain, age, and acuteness. British Journal of Haematology. 156: 535-44. PMID 22171826 DOI: 10.1111/J.1365-2141.2011.08977.X  0.453
2012 Brink TS, Pacharinsak C, Khasabov SG, Beitz AJ, Simone DA. Differential modulation of neurons in the rostral ventromedial medulla by neurokinin-1 receptors. Journal of Neurophysiology. 107: 1210-21. PMID 22031765 DOI: 10.1152/Jn.00678.2011  0.508
2012 Vincent L, Nguyen J, Vang D, Taiwo OB, Luk K, Ansonoff M, Ericson M, Simone D, Pintar JE, Hebbel RP, Gupta K. Mast Cell Activation Contributes to Neurogenic Inflammation and Pain in Sickle Cell Disease Blood. 120: 374-374. DOI: 10.1182/Blood.V120.21.374.374  0.402
2011 Simone DA, Khasabov SG, Cain DM, Hamamoto DT, Khasabova IA. Changes in response properties of nociceptors and dorsal horn neurons in a murine model of cancer pain. Fiziolohichnyĭ Zhurnal (Kiev, Ukraine : 1994). 57: 75-7. PMID 22185016 DOI: 10.15407/Fz57.05.075  0.781
2011 Khasabova IA, Gielissen J, Chandiramani A, Harding-Rose C, Odeh DA, Simone DA, Seybold VS. CB1 and CB2 receptor agonists promote analgesia through synergy in a murine model of tumor pain. Behavioural Pharmacology. 22: 607-16. PMID 21610490 DOI: 10.1097/Fbp.0B013E3283474A6D  0.483
2011 Khasabova IA, Chandiramani A, Harding-Rose C, Simone DA, Seybold VS. Increasing 2-arachidonoyl glycerol signaling in the periphery attenuates mechanical hyperalgesia in a model of bone cancer pain. Pharmacological Research. 64: 60-7. PMID 21440630 DOI: 10.1016/J.Phrs.2011.03.007  0.508
2010 Selim MM, Wendelschafer-Crabb G, Hodges JS, Simone DA, Foster SX, Vanhove GF, Kennedy WR. Variation in quantitative sensory testing and epidermal nerve fiber density in repeated measurements. Pain. 151: 575-81. PMID 20851518 DOI: 10.1016/J.Pain.2010.06.034  0.445
2010 Schmidt BL, Hamamoto DT, Simone DA, Wilcox GL. Mechanism of cancer pain. Molecular Interventions. 10: 164-78. PMID 20539035 DOI: 10.1124/Mi.10.3.7  0.783
2010 Kennedy WR, Vanhove GF, Lu SP, Tobias J, Bley KR, Walk D, Wendelschafer-Crabb G, Simone DA, Selim MM. A randomized, controlled, open-label study of the long-term effects of NGX-4010, a high-concentration capsaicin patch, on epidermal nerve fiber density and sensory function in healthy volunteers. The Journal of Pain : Official Journal of the American Pain Society. 11: 579-87. PMID 20400377 DOI: 10.1016/J.Jpain.2009.09.019  0.452
2010 Kohli DR, Li Y, Khasabov SG, Gupta P, Kehl LJ, Ericson ME, Nguyen J, Gupta V, Hebbel RP, Simone DA, Gupta K. Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids. Blood. 116: 456-65. PMID 20304807 DOI: 10.1182/Blood-2010-01-260372  0.481
2010 Anuforo J, Nguyen J, Luk K, Wallen-Friedman S, Kohli D, Vang D, Ericson M, Simone D, Hebbel RP, Gupta K. Association of Non-Healing Wounds, Pain and Neurochemical Alterations In Sickle Cell Disease Blood. 116: 842-842. DOI: 10.1182/Blood.V116.21.842.842  0.427
2009 Schweizerhof M, Stösser S, Kurejova M, Njoo C, Gangadharan V, Agarwal N, Schmelz M, Bali KK, Michalski CW, Brugger S, Dickenson A, Simone DA, Kuner R. Hematopoietic colony-stimulating factors mediate tumor-nerve interactions and bone cancer pain. Nature Medicine. 15: 802-7. PMID 19525966 DOI: 10.1038/Nm.1976  0.461
2009 Davidson S, Zhang X, Khasabov SG, Simone DA, Giesler GJ. Relief of itch by scratching: state-dependent inhibition of primate spinothalamic tract neurons. Nature Neuroscience. 12: 544-6. PMID 19349977 DOI: 10.1038/Nn.2292  0.445
2009 Potenzieri C, Brink TS, Simone DA. Excitation of cutaneous C nociceptors by intraplantar administration of anandamide. Brain Research. 1268: 38-47. PMID 19285051 DOI: 10.1016/J.Brainres.2009.02.061  0.783
2009 Chizhmakov I, Mamenko N, Volkova T, Khasabova I, Simone DA, Krishtal O. P2X receptors in sensory neurons co-cultured with cancer cells exhibit a decrease in opioid sensitivity European Journal of Neuroscience. 29: 76-86. PMID 19077126 DOI: 10.1111/J.1460-9568.2008.06556.X  0.455
2009 Kohli DR, Li Y, Khasabov SG, Ericson ME, Gupta P, Simone DA, Hebbel RP, Gupta K. Cannabinoids as Analgesics for Pain in Sickle Cell Disease. Blood. 114: 822-822. DOI: 10.1182/Blood.V114.22.822.822  0.488
2008 Khasabova IA, Khasabov SG, Harding-Rose C, Coicou LG, Seybold BA, Lindberg AE, Steevens CD, Simone DA, Seybold VS. A decrease in anandamide signaling contributes to the maintenance of cutaneous mechanical hyperalgesia in a model of bone cancer pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11141-52. PMID 18971457 DOI: 10.1523/Jneurosci.2847-08.2008  0.524
2008 Simone DA, Khasabov SG, Hamamoto DT. Changes in response properties of nociceptive dorsal horn neurons in a murine model of cancer pain. Sheng Li Xue Bao : [Acta Physiologica Sinica]. 60: 635-44. PMID 18958372  0.787
2008 Potenzieri C, Brink TS, Pacharinsak C, Simone DA. Cannabinoid modulation of cutaneous Adelta nociceptors during inflammation. Journal of Neurophysiology. 100: 2794-806. PMID 18784270 DOI: 10.1152/Jn.90809.2008  0.791
2008 Davidson S, Zhang X, Khasabov SG, Simone DA, Giesler GJ. Termination zones of functionally characterized spinothalamic tract neurons within the primate posterior thalamus. Journal of Neurophysiology. 100: 2026-37. PMID 18701750 DOI: 10.1152/Jn.90810.2008  0.371
2008 Hamamoto DT, Khasabov SG, Cain DM, Simone DA. Tumor-evoked sensitization of C nociceptors: a role for endothelin. Journal of Neurophysiology. 100: 2300-11. PMID 18684911 DOI: 10.1152/Jn.01337.2007  0.78
2008 Potenzieri C, Harding-Rose C, Simone DA. The cannabinoid receptor agonist, WIN 55, 212-2, attenuates tumor-evoked hyperalgesia through peripheral mechanisms. Brain Research. 1215: 69-75. PMID 18486111 DOI: 10.1016/J.Brainres.2008.03.063  0.812
2008 Pacharinsak C, Khasabov SG, Beitz AJ, Simone DA. NK-1 receptors in the rostral ventromedial medulla contribute to hyperalgesia produced by intraplantar injection of capsaicin. Pain. 139: 34-46. PMID 18407414 DOI: 10.1016/J.Pain.2008.02.032  0.489
2007 Khasabov SG, Hamamoto DT, Harding-Rose C, Simone DA. Tumor-evoked hyperalgesia and sensitization of nociceptive dorsal horn neurons in a murine model of cancer pain. Brain Research. 1180: 7-19. PMID 17935703 DOI: 10.1016/J.Brainres.2007.08.075  0.805
2007 Khasabova IA, Stucky CL, Harding-Rose C, Eikmeier L, Beitz AJ, Coicou LG, Hanson AE, Simone DA, Seybold VS. Chemical interactions between fibrosarcoma cancer cells and sensory neurons contribute to cancer pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10289-98. PMID 17881535 DOI: 10.1523/Jneurosci.2851-07.2007  0.462
2007 Davidson S, Zhang X, Yoon CH, Khasabov SG, Simone DA, Giesler GJ. The itch-producing agents histamine and cowhage activate separate populations of primate spinothalamic tract neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10007-14. PMID 17855615 DOI: 10.1523/Jneurosci.2862-07.2007  0.397
2007 Hamamoto DT, Giridharagopalan S, Simone DA. Acute and chronic administration of the cannabinoid receptor agonist CP 55,940 attenuates tumor-evoked hyperalgesia. European Journal of Pharmacology. 558: 73-87. PMID 17250825 DOI: 10.1016/J.Ejphar.2006.11.062  0.794
2007 Budai D, Khasabov SG, Mantyh PW, Simone DA. NK-1 receptors modulate the excitability of ON cells in the rostral ventromedial medulla. Journal of Neurophysiology. 97: 1388-95. PMID 17182914 DOI: 10.1152/Jn.00450.2006  0.414
2005 Gilchrist LS, Cain DM, Harding-Rose C, Kov AN, Wendelschafer-Crabb G, Kennedy WR, Simone DA. Re-organization of P2X3 receptor localization on epidermal nerve fibers in a murine model of cancer pain. Brain Research. 1044: 197-205. PMID 15885218 DOI: 10.1016/J.Brainres.2005.02.081  0.461
2005 Wacnik PW, Eikmeier LJ, Simone DA, Wilcox GL, Beitz AJ. Nociceptive characteristics of tumor necrosis factor-alpha in naive and tumor-bearing mice. Neuroscience. 132: 479-91. PMID 15802198 DOI: 10.1016/J.Neuroscience.2004.12.035  0.309
2005 Khasabov SG, Ghilardi JR, Mantyh PW, Simone DA. Spinal neurons that express NK-1 receptors modulate descending controls that project through the dorsolateral funiculus. Journal of Neurophysiology. 93: 998-1006. PMID 15456795 DOI: 10.1152/Jn.01160.2003  0.435
2005 Johanek LM, Simone DA. Cannabinoid agonist, CP 55,940, prevents capsaicin-induced sensitization of spinal cord dorsal horn neurons. Journal of Neurophysiology. 93: 989-97. PMID 15385593 DOI: 10.1152/Jn.00673.2004  0.772
2004 Johanek LM, Simone DA. Activation of peripheral cannabinoid receptors attenuates cutaneous hyperalgesia produced by a heat injury. Pain. 109: 432-42. PMID 15157704 DOI: 10.1016/J.Pain.2004.02.020  0.772
2004 Khasabova IA, Harding-Rose C, Simone DA, Seybold VS. Differential Effects of CB1 and Opioid Agonists on Two Populations of Adult Rat Dorsal Root Ganglion Neurons Journal of Neuroscience. 24: 1744-1753. PMID 14973253 DOI: 10.1523/Jneurosci.4298-03.2004  0.403
2004 Simone DA, Zhang X, Li J, Zhang JM, Honda CN, LaMotte RH, Giesler GJ. Comparison of responses of primate spinothalamic tract neurons to pruritic and algogenic stimuli. Journal of Neurophysiology. 91: 213-22. PMID 14715718 DOI: 10.1152/Jn.00527.2003  0.457
2003 Hamamoto DT, Simone DA. Characterization of cutaneous primary afferent fibers excited by acetic acid in a model of nociception in frogs. Journal of Neurophysiology. 90: 566-77. PMID 12750420 DOI: 10.1152/Jn.00324.2003  0.738
2003 Kehl LJ, Hamamoto DT, Wacnik PW, Croft DL, Norsted BD, Wilcox GL, Simone DA. A cannabinoid agonist differentially attenuates deep tissue hyperalgesia in animal models of cancer and inflammatory muscle pain. Pain. 103: 175-86. PMID 12749972 DOI: 10.1016/S0304-3959(02)00450-5  0.79
2003 Turner MS, Hamamoto DT, Hodges JS, Maccecchini ML, Simone DA. SYM 2081, an agonist that desensitizes kainate receptors, attenuates capsaicin and inflammatory hyperalgesia. Brain Research. 973: 252-64. PMID 12738069 DOI: 10.1016/S0006-8993(03)02525-3  0.774
2002 Khasabova IA, Simone DA, Seybold VS. Cannabinoids attenuate depolarization-dependent Ca2+ influx in intermediate-size primary afferent neurons of adult rats Neuroscience. 115: 613-625. PMID 12421626 DOI: 10.1016/S0306-4522(02)00449-9  0.395
2002 Khasabov SG, Rogers SD, Ghilardi JR, Peters CM, Mantyh PW, Simone DA. Spinal neurons that possess the substance P receptor are required for the development of central sensitization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9086-98. PMID 12388616 DOI: 10.1523/Jneurosci.22-20-09086.2002  0.464
2002 Reichert JA, Daughters RS, Rivard R, Simone DA. Peripheral and preemptive opiod anticocieption in a mouse visceral pain model | Antinocicepción opiácea periférica y preventiva en un modelo de dolor visceral en ratón Revista De La Sociedad Espanola Del Dolor. 9: 423-431.  0.335
2001 Cain DM, Wacnik PW, Eikmeier L, Beitz A, Wilcox GL, Simone DA. Functional interactions between tumor and peripheral nerve in a model of cancer pain in the mouse. Pain Medicine (Malden, Mass.). 2: 15-23. PMID 15102313 DOI: 10.1046/J.1526-4637.2001.002001015.X  0.469
2001 Cain DM, Wacnik PW, Turner M, Wendelschafer-Crabb G, Kennedy WR, Wilcox GL, Simone DA. Functional interactions between tumor and peripheral nerve: changes in excitability and morphology of primary afferent fibers in a murine model of cancer pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9367-76. PMID 11717370 DOI: 10.1046/J.1529-8027.2002.02011_5.X  0.417
2001 Guo A, Simone DA, Stone LS, Fairbanks CA, Wang J, Elde R. Developmental shift of vanilloid receptor 1 (VR1) terminals into deeper regions of the superficial dorsal horn: correlation with a shift from TrkA to Ret expression by dorsal root ganglion neurons. The European Journal of Neuroscience. 14: 293-304. PMID 11553280 DOI: 10.1046/J.0953-816X.2001.01665.X  0.385
2001 Johanek LM, Heitmiller DR, Turner M, Nader N, Hodges J, Simone DA. Cannabinoids attenuate capsaicin-evoked hyperalgesia through spinal and peripheral mechanisms. Pain. 93: 303-15. PMID 11514089 DOI: 10.1016/S0304-3959(01)00336-0  0.785
2001 Khasabov SG, Cain DM, Thong D, Mantyh PW, Simone DA. Enhanced responses of spinal dorsal horn neurons to heat and cold stimuli following mild freeze injury to the skin Journal of Neurophysiology. 86: 986-996. PMID 11495966 DOI: 10.1152/Jn.2001.86.2.986  0.391
2001 Cain DM, Khasabov SG, Simone DA. Response properties of mechanoreceptors and nociceptors in mouse glabrous skin: An in vivo study Journal of Neurophysiology. 85: 1561-1574. PMID 11287480 DOI: 10.1152/Jn.2001.85.4.1561  0.371
2001 Khalili N, Wendelschafer-Crabb G, Kennedy WR, Simone DA. Influence of thermode size for detecting heat pain dysfunction in a capsaicin model of epidermal nerve fiber loss Pain. 91: 241-250. PMID 11275380 DOI: 10.1016/S0304-3959(00)00444-9  0.476
2001 Cain DM, Wacnik PW, Simone DA. Animal models of cancer pain may reveal novel approaches to palliative care Pain. 91: 1-4. PMID 11240072 DOI: 10.1016/S0304-3959(01)00287-1  0.372
2001 Reichert JA, Daughters RS, Rivard R, Simone DA. Peripheral and preemptive opioid antinociception in a mouse visceral pain model Pain. 89: 221-227. PMID 11166478 DOI: 10.1016/S0304-3959(00)00365-1  0.436
2000 Hamamoto DT, Forkey MW, Davis WL, Kajander KC, Simone DA. The role of pH and osmolarity in evoking the acetic acid-induced wiping response in a model of nociception in frogs. Brain Research. 862: 217-29. PMID 10799688 DOI: 10.1016/S0006-8993(00)02138-7  0.72
2000 Simone DA, Seybold VS. Cannabinoids: Worthwhile analgesics? Journal of Pain. 1: 18-19. DOI: 10.1016/S1526-5900(00)90084-1  0.403
1999 Nichols ML, Allen BJ, Rogers SD, Ghilardi JR, Honore P, Luger NM, Finke MP, Li J, Lappi DA, Simone DA, Mantyh PW. Transmission of chronic nociception by spinal neurons expressing the substance P receptor. Science (New York, N.Y.). 286: 1558-61. PMID 10567262 DOI: 10.1126/Science.286.5444.1558  0.508
1999 Nolano M, Simone DA, Wendelschafer-Crabb G, Johnson T, Hazen E, Kennedy WR. Topical capsaicin in humans: Parallel loss of epidermal nerve fibers and pain sensation Pain. 81: 135-145. PMID 10353501 DOI: 10.1016/S0304-3959(99)00007-X  0.45
1999 Li J, Daughters RS, Bullis C, Bengiamin R, Stucky MW, Brennan J, Simone DA. The cannabinoid receptor agonist WIN 55,212-2 mesylate blocks the development of hyperalgesia produced by capsaicin in rats. Pain. 81: 25-33. PMID 10353490 DOI: 10.1016/S0304-3959(98)00263-2  0.548
1999 Allen BJ, Li J, Menning PM, Rogers SD, Ghilardi J, Mantyh PW, Simone DA. Primary afferent fibers that contribute to increased substance P receptor internalization in the spinal cord after injury. Journal of Neurophysiology. 81: 1379-90. PMID 10085363 DOI: 10.1152/Jn.1999.81.3.1379  0.401
1999 Li J, Simone DA, Larson AA. Windup leads to characteristics of central sensitization. Pain. 79: 75-82. PMID 9928779 DOI: 10.1016/S0304-3959(98)00154-7  0.404
1998 Simone DA, Nolano M, Johnson T, Wendelschafer-Crabb G, Kennedy WR. Intradermal injection of capsaicin in humans produces degeneration and subsequent reinnervation of epidermal nerve fibers: Correlation with sensory function Journal of Neuroscience. 18: 8947-8959. PMID 9787000 DOI: 10.1523/Jneurosci.18-21-08947.1998  0.404
1997 Mantyh PW, Rogers SD, Honore P, Allen BJ, Ghilardi JR, Li J, Daughters RS, Lappi DA, Wiley RG, Simone DA. Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptor. Science (New York, N.Y.). 278: 275-9. PMID 9323204 DOI: 10.1126/Science.278.5336.275  0.421
1997 Allen BJ, Rogers SD, Ghilardi JR, Menning PM, Kuskowski MA, Basbaum AI, Simone DA, Mantyh PW. Noxious cutaneous thermal stimuli induce a graded release of endogenous substance P in the spinal cord: imaging peptide action in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5921-7. PMID 9221788 DOI: 10.1523/Jneurosci.17-15-05921.1997  0.427
1997 Simone DA, Kajander KC. Responses of cutaneous A-fiber nociceptors to noxious cold Journal of Neurophysiology. 77: 2049-2060. PMID 9114254 DOI: 10.1152/Jn.1997.77.4.2049  0.355
1997 Simone DA, Marchettini P, Ochoa JL. Reply to the commentaries Pain Forum. 6: 225-227. DOI: 10.1016/S1082-3174(97)70014-X  0.438
1997 Simone DA, Marchettini P, Ochoa JL. Primary afferent nerve fibers that contribute to muscle pain sensation in humans Pain Forum. 6: 207-212. DOI: 10.1016/S1082-3174(97)70004-7  0.4
1996 Marchettini P, Simone DA, Caputi G, Ochoa JL. Pain from excitation of identified muscle nociceptors in humans Brain Research. 740: 109-116. PMID 8973804 DOI: 10.1016/S0006-8993(96)00851-7  0.435
1996 Gilchrist HD, Allard BL, Simone DA. Enhanced withdrawal responses to heat and mechanical stimuli following intraplantar injection of Capsaicin in rats Pain. 67: 179-188. PMID 8895246 DOI: 10.1016/0304-3959(96)03104-1  0.445
1996 Simone DA, Kajander KC. Excitation of rat cutaneous nociceptors by noxious cold Neuroscience Letters. 213: 53-56. PMID 8844711 DOI: 10.1016/0304-3940(96)12838-X  0.367
1994 Simone DA, Marchettini P, Caputi G, Ochoa JL. Identification of muscle afferents subserving sensation of deep pain in humans Journal of Neurophysiology. 72: 883-889. PMID 7983543 DOI: 10.1152/Jn.1994.72.2.883  0.441
1993 Simone DA, Hanson ME, Bernau NA, Pubols BH. Nociceptive neurons of the raccoon lateral thalamus Journal of Neurophysiology. 69: 318-328. PMID 8459269 DOI: 10.1152/Jn.1993.69.2.318  0.37
1993 Simone DA. Mediators of spinal hyperexcitability and hyperalgesia Aps Journal. 2: 283-286. DOI: 10.1016/S1058-9139(05)80260-8  0.453
1992 Simone DA. Neural mechanisms of hyperalgesia Current Opinion in Neurobiology. 2: 479-483. PMID 1525546 DOI: 10.1016/0960-9822(92)90685-4  0.456
1992 Yarnitsky D, Simone DA, Dotson RM, Cline MA, Ochoa JL. Single C nociceptor responses and psychophysical parameters of evoked pain: effect of rate of rise of heat stimuli in humans. The Journal of Physiology. 450: 581-92. PMID 1432719 DOI: 10.1113/Jphysiol.1992.Sp019144  0.42
1991 Simone DA, Sorkin LS, Oh U, Chung JM, Owens C, LaMotte RH, Willis WD. Neurogenic hyperalgesia: central neural correlates in responses of spinothalamic tract neurons. Journal of Neurophysiology. 66: 228-46. PMID 1919669 DOI: 10.1152/Jn.1991.66.1.228  0.505
1991 Baumann TK, Simone DA, Shain CN, LaMotte RH. Neurogenic hyperalgesia: the search for the primary cutaneous afferent fibers that contribute to capsaicin-induced pain and hyperalgesia. Journal of Neurophysiology. 66: 212-27. PMID 1919668 DOI: 10.1152/Jn.1991.66.1.212  0.506
1991 LaMotte RH, Shain CN, Simone DA, Tsai EF. Neurogenic hyperalgesia: psychophysical studies of underlying mechanisms. Journal of Neurophysiology. 66: 190-211. PMID 1919666 DOI: 10.1152/Jn.1991.66.1.190  0.476
1991 Simone DA, Pubols BH. The raccoon lateral cervical nucleus: A single-unit analysis Journal of Neurophysiology. 65: 1411-1421. PMID 1875250 DOI: 10.1152/Jn.1991.65.6.1411  0.338
1991 Simone DA, Ochoa J. Early and late effects of prolonged topical capsaicin on cutaneous sensibility and neurogenic vasodilatation in humans Pain. 47: 285-294. PMID 1784499 DOI: 10.1016/0304-3959(91)90217-L  0.471
1991 Simone DA, Alreja M, LaMotte RH. Psychophysical studies of the itch sensation and itchy skin ("alloknesis") produced by intracutaneous injection of histamine. Somatosensory & Motor Research. 8: 271-9. PMID 1767623 DOI: 10.3109/08990229109144750  0.401
1989 Simone DA, Baumann TK, LaMotte RH. Dose-dependent pain and mechanical hyperalgesia in humans after intradermal injection of capsaicin. Pain. 38: 99-107. PMID 2780068 DOI: 10.1016/0304-3959(89)90079-1  0.444
1989 Simone DA, Baumann TK, Collins JG, LaMotte RH. Sensitization of cat dorsal horn neurons to innocuous mechanical stimulation after intradermal injection of capsaicin. Brain Research. 486: 185-9. PMID 2720428 DOI: 10.1016/0006-8993(89)91293-6  0.431
1987 Simone DA, Ngeow JY, Putterman GJ, LaMotte RH. Hyperalgesia to heat after intradermal injection of capsaicin. Brain Research. 418: 201-3. PMID 3664271 DOI: 10.1016/0006-8993(87)90982-6  0.455
1987 Simone DA, Ngeow JY, Whitehouse J, Becerra-Cabal L, Putterman GJ, LaMotte RH. The magnitude and duration of itch produced by intracutaneous injections of histamine. Somatosensory Research. 5: 81-92. PMID 3423533 DOI: 10.3109/07367228709144620  0.344
1987 LaMotte RH, Simone DA, Baumann TK, Shain CN, Alreja M. Hypothesis for novel classes of chemoreceptors mediating chemogenic pain and itch Pain. 30: S15. DOI: 10.1016/0304-3959(87)91109-2  0.419
1983 Bodnar RJ, Simone DA, Kordower JH, Kirchgessner AL, Nilaver G. Capsaicin treatment and stress-induced analgesia. Pharmacology, Biochemistry, and Behavior. 18: 65-71. PMID 6681908 DOI: 10.1016/0091-3057(83)90253-8  0.31
1983 Simone DA, Bodnar RJ. Tail-pinch hyperalgesia and analgesia: Test-specific opioid and nonopioid actions Learning and Motivation. 14: 367-379. DOI: 10.1016/0023-9690(83)90023-1  0.304
1982 Bodnar RJ, Simone D, Kelly DD, Brutus M, Glusman M, Meibach R. Time-dependent and dose-dependent effects of fenfluramine upon pain thresholds Bulletin of the Psychonomic Society. 19: 355-358. DOI: 10.3758/BF03330281  0.312
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