Issar Smith - Publications

Affiliations: 
1967-2004 New York University, New York, NY, United States 
 2004-2015 University of Medicine and Dentistry of New Jersey, Piscataway Township, New Jersey, United States 
Area:
Microbiology Biology
Website:
https://phri.njms.rutgers.edu/faculty-and-research/emeritus-faculty/

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Yang X, Gao J, Smith I, Dubnau E, Sampson NS. Cholesterol is not an essential source of nutrition for Mycobacterium tuberculosis during infection. Journal of Bacteriology. 193: 1473-6. PMID 21257778 DOI: 10.1128/Jb.01210-10  0.339
2010 Hernandez Pando R, Aguilar LD, Smith I, Manganelli R. Immunogenicity and protection induced by a Mycobacterium tuberculosis sigE mutant in a BALB/c mouse model of progressive pulmonary tuberculosis. Infection and Immunity. 78: 3168-76. PMID 20457786 DOI: 10.1128/Iai.00023-10  0.355
2010 Ryndak MB, Wang S, Smith I, Rodriguez GM. The Mycobacterium tuberculosis high-affinity iron importer, IrtA, contains an FAD-binding domain. Journal of Bacteriology. 192: 861-9. PMID 19948799 DOI: 10.1128/Jb.00223-09  0.379
2010 Nesbitt NM, Yang X, Fontán P, Kolesnikova I, Smith I, Sampson NS, Dubnau E. A thiolase of Mycobacterium tuberculosis is required for virulence and production of androstenedione and androstadienedione from cholesterol. Infection and Immunity. 78: 275-82. PMID 19822655 DOI: 10.1128/Iai.00893-09  0.412
2009 Janagama HK, Senthilkumar TM, Bannantine JP, Rodriguez GM, Smith I, Paustian ML, McGarvey JA, Sreevatsan S. Identification and functional characterization of the iron-dependent regulator (IdeR) of Mycobacterium avium subsp. paratuberculosis. Microbiology (Reading, England). 155: 3683-90. PMID 19684064 DOI: 10.1099/Mic.0.031948-0  0.397
2009 Fontán PA, Voskuil MI, Gomez M, Tan D, Pardini M, Manganelli R, Fattorini L, Schoolnik GK, Smith I. The Mycobacterium tuberculosis sigma factor sigmaB is required for full response to cell envelope stress and hypoxia in vitro, but it is dispensable for in vivo growth. Journal of Bacteriology. 191: 5628-33. PMID 19592585 DOI: 10.1128/Jb.00510-09  0.394
2008 Ryndak M, Wang S, Smith I. PhoP, a key player in Mycobacterium tuberculosis virulence. Trends in Microbiology. 16: 528-34. PMID 18835713 DOI: 10.1016/J.Tim.2008.08.006  0.424
2008 Rao PK, Rodriguez GM, Smith I, Li Q. Protein dynamics in iron-starved Mycobacterium tuberculosis revealed by turnover and abundance measurement using hybrid-linear ion trap-Fourier transform mass spectrometry. Analytical Chemistry. 80: 6860-9. PMID 18690695 DOI: 10.1021/Ac800288T  0.349
2008 Fontán PA, Aris V, Alvarez ME, Ghanny S, Cheng J, Soteropoulos P, Trevani A, Pine R, Smith I. Mycobacterium tuberculosis sigma factor E regulon modulates the host inflammatory response. The Journal of Infectious Diseases. 198: 877-85. PMID 18657035 DOI: 10.1086/591098  0.456
2008 Fontán P, Aris V, Ghanny S, Soteropoulos P, Smith I. Global transcriptional profile of Mycobacterium tuberculosis during THP-1 human macrophage infection. Infection and Immunity. 76: 717-25. PMID 18070897 DOI: 10.1128/Iai.00974-07  0.473
2007 Williams DL, Pittman TL, Deshotel M, Oby-Robinson S, Smith I, Husson R. Molecular basis of the defective heat stress response in Mycobacterium leprae. Journal of Bacteriology. 189: 8818-27. PMID 17933896 DOI: 10.1128/Jb.00601-07  0.346
2007 Yang X, Dubnau E, Smith I, Sampson NS. Rv1106c from Mycobacterium tuberculosis is a 3beta-hydroxysteroid dehydrogenase. Biochemistry. 46: 9058-67. PMID 17630785 DOI: 10.1021/Bi700688X  0.336
2007 Rehren G, Walters S, Fontan P, Smith I, Zárraga AM. Differential gene expression between Mycobacterium bovis and Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 87: 347-59. PMID 17433778 DOI: 10.1016/J.Tube.2007.02.004  0.762
2007 Maciag A, Dainese E, Rodriguez GM, Milano A, Provvedi R, Pasca MR, Smith I, Palù G, Riccardi G, Manganelli R. Global analysis of the Mycobacterium tuberculosis Zur (FurB) regulon. Journal of Bacteriology. 189: 730-40. PMID 17098899 DOI: 10.1128/Jb.01190-06  0.508
2006 Giacomini E, Sotolongo A, Iona E, Severa M, Remoli ME, Gafa V, Lande R, Fattorini L, Smith I, Manganelli R, Coccia EM. Infection of human dendritic cells with a Mycobacterium tuberculosis sigE mutant stimulates production of high levels of interleukin-10 but low levels of CXCL10: impact on the T-cell response. Infection and Immunity. 74: 3296-304. PMID 16714557 DOI: 10.1128/Iai.01687-05  0.345
2006 Walters SB, Dubnau E, Kolesnikova I, Laval F, Daffe M, Smith I. The Mycobacterium tuberculosis PhoPR two-component system regulates genes essential for virulence and complex lipid biosynthesis. Molecular Microbiology. 60: 312-30. PMID 16573683 DOI: 10.1111/J.1365-2958.2006.05102.X  0.756
2006 Dainese E, Rodrigue S, Delogu G, Provvedi R, Laflamme L, Brzezinski R, Fadda G, Smith I, Gaudreau L, Palù G, Manganelli R. Posttranslational regulation of Mycobacterium tuberculosis extracytoplasmic-function sigma factor sigma L and roles in virulence and in global regulation of gene expression. Infection and Immunity. 74: 2457-61. PMID 16552079 DOI: 10.1128/Iai.74.4.2457-2461.2006  0.481
2006 Rodriguez GM, Smith I. Identification of an ABC transporter required for iron acquisition and virulence in Mycobacterium tuberculosis. Journal of Bacteriology. 188: 424-30. PMID 16385031 DOI: 10.1128/Jb.188.2.424-430.2006  0.453
2005 Mendelson M, Walters S, Smith I, Kaplan G. Strain-specific mycobacterial lipids and the stimulation of protective immunity to tuberculosis. Tuberculosis (Edinburgh, Scotland). 85: 407-13. PMID 16249121 DOI: 10.1016/J.Tube.2005.08.004  0.725
2005 Smith I, Nathan C, Peavy HH. Progress and new directions in genetics of tuberculosis: an NHLBI working group report. American Journal of Respiratory and Critical Care Medicine. 172: 1491-6. PMID 16192449 DOI: 10.1164/Rccm.200506-997Ws  0.382
2005 Dubnau E, Chan J, Mohan VP, Smith I. responses of mycobacterium tuberculosis to growth in the mouse lung. Infection and Immunity. 73: 3754-7. PMID 15908407 DOI: 10.1128/Iai.73.6.3754-3757.2005  0.394
2004 Marras SA, Gold B, Kramer FR, Smith I, Tyagi S. Real-time measurement of in vitro transcription. Nucleic Acids Research. 32: e72. PMID 15155820 DOI: 10.1093/Nar/Gnh068  0.631
2004 Manganelli R, Fattorini L, Tan D, Iona E, Orefici G, Altavilla G, Cusatelli P, Smith I. The extra cytoplasmic function sigma factor sigma(E) is essential for Mycobacterium tuberculosis virulence in mice. Infection and Immunity. 72: 3038-41. PMID 15102817 DOI: 10.1128/Iai.72.5.3038-3041.2004  0.366
2004 Manganelli R, Provvedi R, Rodrigue S, Beaucher J, Gaudreau L, Smith I, Proveddi R. Sigma factors and global gene regulation in Mycobacterium tuberculosis. Journal of Bacteriology. 186: 895-902. PMID 14761983 DOI: 10.1128/Jb.186.4.895-902.2004  0.378
2003 Timm J, Post FA, Bekker LG, Walther GB, Wainwright HC, Manganelli R, Chan WT, Tsenova L, Gold B, Smith I, Kaplan G, McKinney JD. Differential expression of iron-, carbon-, and oxygen-responsive mycobacterial genes in the lungs of chronically infected mice and tuberculosis patients. Proceedings of the National Academy of Sciences of the United States of America. 100: 14321-6. PMID 14623960 DOI: 10.1073/Pnas.2436197100  0.699
2003 Smith I. Mycobacterium tuberculosis pathogenesis and molecular determinants of virulence. Clinical Microbiology Reviews. 16: 463-96. PMID 12857778 DOI: 10.1128/Cmr.16.3.463-496.2003  0.387
2003 Dubnau E, Smith I. Mycobacterium tuberculosis gene expression in macrophages. Microbes and Infection / Institut Pasteur. 5: 629-37. PMID 12787739 DOI: 10.1016/S1286-4579(03)00090-X  0.45
2003 Rodriguez GM, Smith I. Mechanisms of iron regulation in mycobacteria: role in physiology and virulence. Molecular Microbiology. 47: 1485-94. PMID 12622807 DOI: 10.1046/J.1365-2958.2003.03384.X  0.39
2002 Beaucher J, Rodrigue S, Jacques PE, Smith I, Brzezinski R, Gaudreau L. Novel Mycobacterium tuberculosis anti-sigma factor antagonists control sigmaF activity by distinct mechanisms. Molecular Microbiology. 45: 1527-40. PMID 12354223 DOI: 10.1046/J.1365-2958.2002.03135.X  0.316
2002 Manganelli R, Voskuil MI, Schoolnik GK, Dubnau E, Gomez M, Smith I. Role of the extracytoplasmic-function sigma factor sigma(H) in Mycobacterium tuberculosis global gene expression. Molecular Microbiology. 45: 365-74. PMID 12123450 DOI: 10.1046/J.1365-2958.2002.03005.X  0.493
2002 Raynaud C, Guilhot C, Rauzier J, Bordat Y, Pelicic V, Manganelli R, Smith I, Gicquel B, Jackson M. Phospholipases C are involved in the virulence of Mycobacterium tuberculosis. Molecular Microbiology. 45: 203-17. PMID 12100560 DOI: 10.1046/J.1365-2958.2002.03009.X  0.482
2002 Rodriguez GM, Voskuil MI, Gold B, Schoolnik GK, Smith I. ideR, An essential gene in mycobacterium tuberculosis: role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress response. Infection and Immunity. 70: 3371-81. PMID 12065475 DOI: 10.1128/Iai.70.7.3371-3381.2002  0.732
2002 Dubnau E, Fontán P, Manganelli R, Soares-Appel S, Smith I. Mycobacterium tuberculosis genes induced during infection of human macrophages. Infection and Immunity. 70: 2787-95. PMID 12010964 DOI: 10.1128/Iai.70.6.2787-2795.2002  0.454
2002 Shafikhani SH, Mandic-Mulec I, Strauch MA, Smith I, Leighton T. Postexponential regulation of sin operon expression in Bacillus subtilis. Journal of Bacteriology. 184: 564-71. PMID 11751836 DOI: 10.1128/Jb.184.2.564-571.2002  0.383
2001 Gold B, Rodriguez GM, Marras SA, Pentecost M, Smith I. The Mycobacterium tuberculosis IdeR is a dual functional regulator that controls transcription of genes involved in iron acquisition, iron storage and survival in macrophages. Molecular Microbiology. 42: 851-65. PMID 11722747 DOI: 10.1046/J.1365-2958.2001.02684.X  0.73
2001 Manganelli R, Voskuil MI, Schoolnik GK, Smith I. The Mycobacterium tuberculosis ECF sigma factor sigmaE: role in global gene expression and survival in macrophages. Molecular Microbiology. 41: 423-37. PMID 11489128 DOI: 10.1046/J.1365-2958.2001.02525.X  0.485
2000 Shin BS, Choi SK, Smith I, Park SH. Analysis of tnrA alleles which result in a glucose-resistant sporulation phenotype in Bacillus subtilis. Journal of Bacteriology. 182: 5009-12. PMID 10940050 DOI: 10.1128/Jb.182.17.5009-5012.2000  0.418
2000 Dubnau E, Chan J, Raynaud C, Mohan VP, Lanéelle MA, Yu K, Quémard A, Smith I, Daffé M. Oxygenated mycolic acids are necessary for virulence of Mycobacterium tuberculosis in mice. Molecular Microbiology. 36: 630-7. PMID 10844652 DOI: 10.1046/J.1365-2958.2000.01882.X  0.343
1999 Rodriguez GM, Gold B, Gomez M, Dussurget O, Smith I. Identification and characterization of two divergently transcribed iron regulated genes in Mycobacterium tuberculosis. Tubercle and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease. 79: 287-98. PMID 10707257 DOI: 10.1054/Tuld.1999.0219  0.704
1999 Dussurget O, Timm J, Gomez M, Gold B, Yu S, Sabol SZ, Holmes RK, Jacobs WR, Smith I. Transcriptional control of the iron-responsive fxbA gene by the mycobacterial regulator IdeR Journal of Bacteriology. 181: 3402-3408. PMID 10348851 DOI: 10.1128/Jb.181.11.3402-3408.1999  0.711
1999 Manganelli R, Dubnau E, Tyagi S, Kramer FR, Smith I. Differential expression of 10 sigma factor genes in Mycobacterium tuberculosis. Molecular Microbiology. 31: 715-24. PMID 10027986 DOI: 10.1046/J.1365-2958.1999.01212.X  0.484
1998 Smith I, Dussurget O, Rodriguez GM, Timm J, Gomez M, Dubnau J, Gold B, Manganelli R. Extra and intracellular expression of Mycobacterium tuberculosis genes. Tubercle and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease. 79: 91-7. PMID 10645446 DOI: 10.1054/Tuld.1998.0010  0.746
1998 Lewis RJ, Brannigan JA, Offen WA, Smith I, Wilkinson AJ. An evolutionary link between sporulation and prophage induction in the structure of a repressor:anti-repressor complex. Journal of Molecular Biology. 283: 907-12. PMID 9799632 DOI: 10.1006/Jmbi.1998.2163  0.332
1998 Dussurget O, Smith I. Interdependence of mycobacterial iron regulation, oxidative-stress response and isoniazid resistance. Trends in Microbiology. 6: 354-8. PMID 9778728 DOI: 10.1016/S0966-842X(98)01307-9  0.347
1998 Gomez M, Doukhan L, Nair G, Smith I. sigA is an essential gene in Mycobacterium smegmatis. Molecular Microbiology. 29: 617-28. PMID 9720877 DOI: 10.1046/J.1365-2958.1998.00960.X  0.467
1996 Dussurget O, Rodriguez M, Smith I. An ideR mutant of Mycobacterium smegmatis has derepressed siderophore production and an altered oxidative-stress response. Molecular Microbiology. 22: 535-44. PMID 8939436 DOI: 10.1046/J.1365-2958.1996.1461511.X  0.406
1995 Predich M, Doukhan L, Nair G, Smith I. Characterization of RNA polymerase and two sigma-factor genes from Mycobacterium smegmatis. Molecular Microbiology. 15: 355-66. PMID 7746156 DOI: 10.1111/J.1365-2958.1995.Tb02249.X  0.428
1995 Mandic-Mulec I, Doukhan L, Smith I. The Bacillus subtilis SinR protein is a repressor of the key sporulation gene spo0A. Journal of Bacteriology. 177: 4619-27. PMID 7642487 DOI: 10.1128/Jb.177.16.4619-4627.1995  0.43
1995 Schmitt MP, Predich M, Doukhan L, Smith I, Holmes RK. Characterization of an iron-dependent regulatory protein (IdeR) of Mycobacterium tuberculosis as a functional homolog of the diphtheria toxin repressor (DtxR) from Corynebacterium diphtheriae Infection and Immunity. 63: 4284-4289. PMID 7591059 DOI: 10.1128/Iai.63.11.4284-4289.1995  0.444
1995 Doukhan L, Predich M, Nair G, Dussurget O, Mandic-Mulec I, Cole ST, Smith DR, Smith I. Genomic organization of the mycobacterial sigma gene cluster. Gene. 165: 67-70. PMID 7489918 DOI: 10.1016/0378-1119(95)00427-8  0.427
1993 Bai U, Mandic-Mulec I, Smith I. SinI modulates the activity of SinR, a developmental switch protein of Bacillus subtilis, by protein-protein interaction. Genes & Development. 7: 139-48. PMID 8422983 DOI: 10.1101/Gad.7.1.139  0.419
1992 Mandic-Mulec I, Gaur N, Bai U, Smith I. Sin, a stage-specific repressor of cellular differentiation. Journal of Bacteriology. 174: 3561-9. PMID 1592811 DOI: 10.1128/Jb.174.11.3561-3569.1992  0.382
1992 Predich M, Nair G, Smith I. Bacillus subtilis early sporulation genes kinA, spo0F, and spo0A are transcribed by the RNA polymerase containing sigma H. Journal of Bacteriology. 174: 2771-8. PMID 1569009 DOI: 10.1128/Jb.174.9.2771-2778.1992  0.426
1992 Smith I, Dubnau E, Predich M, Bai U, Rudner R. Early spo gene expression in Bacillus subtilis: the role of interrelated signal transduction systems. Biochimie. 74: 669-78. PMID 1391046 DOI: 10.1016/0300-9084(92)90139-6  0.388
1991 Healy J, Weir J, Smith I, Losick R. Post-transcriptional control of a sporulation regulatory gene encoding transcription factor sigma H in Bacillus subtilis. Molecular Microbiology. 5: 477-87. PMID 1904128 DOI: 10.1111/J.1365-2958.1991.Tb02131.X  0.399
1991 Gaur NK, Oppenheim J, Smith I. The Bacillus subtilis sin gene, a regulator of alternate developmental processes, codes for a DNA-binding protein. Journal of Bacteriology. 173: 678-86. PMID 1898931 DOI: 10.1128/Jb.173.2.678-686.1991  0.391
1991 Weir J, Predich M, Dubnau E, Nair G, Smith I. Regulation of spo0H, a gene coding for the Bacillus subtilis sigma H factor. Journal of Bacteriology. 173: 521-9. PMID 1898930 DOI: 10.1128/Jb.173.2.521-529.1991  0.434
1991 Smith I, Mandić-Mulec I, Gaur N. The role of negative control in sporulation. Research in Microbiology. 142: 831-9. PMID 1664536 DOI: 10.1016/0923-2508(91)90062-F  0.418
1990 Bai U, Lewandoski M, Dubnau E, Smith I. Temporal regulation of the Bacillus subtilis early sporulation gene spo0F. Journal of Bacteriology. 172: 5432-9. PMID 2118512 DOI: 10.1128/Jb.172.9.5432-5439.1990  0.666
1990 Weinrauch Y, Penchev R, Dubnau E, Smith I, Dubnau D. A Bacillus subtilis regulatory gene product for genetic competence and sporulation resembles sensor protein members of the bacterial two-component signal-transduction systems. Genes & Development. 4: 860-72. PMID 2116363 DOI: 10.1101/Gad.4.5.860  0.4
1988 Dubnau E, Weir J, Nair G, Carter L, Moran C, Smith I. Bacillus sporulation gene spo0H codes for sigma 30 (sigma H). Journal of Bacteriology. 170: 1054-62. PMID 3277943 DOI: 10.1128/Jb.170.3.1054-1062.1988  0.362
1988 Lewandoski M, Smith I. Use of a versatile lacZ vector to analyze the upstream region of the Bacillus subtilis spoOF gene. Plasmid. 20: 148-54. PMID 3148946 DOI: 10.1016/0147-619X(88)90018-2  0.654
1988 Gaur NK, Cabane K, Smith I. Structure and expression of the Bacillus subtilis sin operon. Journal of Bacteriology. 170: 1046-53. PMID 3125149 DOI: 10.1128/Jb.170.3.1046-1053.1988  0.452
1987 Dubnau EJ, Cabane K, Smith I. Regulation of spo0H, an early sporulation gene in bacilli. Journal of Bacteriology. 169: 1182-91. PMID 3102457 DOI: 10.1128/Jb.169.3.1182-1191.1987  0.436
1986 Gaur NK, Dubnau E, Smith I. Characterization of a cloned Bacillus subtilis gene that inhibits sporulation in multiple copies. Journal of Bacteriology. 168: 860-9. PMID 3096962 DOI: 10.1128/Jb.168.2.860-869.1986  0.36
1986 Lewandoski M, Dubnau E, Smith I. Transcriptional regulation of the spo0F gene of Bacillus subtilis. Journal of Bacteriology. 168: 870-7. PMID 2430944 DOI: 10.1128/Jb.168.2.870-877.1986  0.626
1984 Weir J, Dubnau E, Ramakrishna N, Smith I. Bacillus subtilis spo0H gene. Journal of Bacteriology. 157: 405-12. PMID 6420389 DOI: 10.1128/Jb.157.2.405-412.1984  0.377
1984 Ramakrishna N, Dubnau E, Smith I. The complete DNA sequence and regulatory regions of the Bacillus licheniformis spoOH gene. Nucleic Acids Research. 12: 1779-90. PMID 6322121 DOI: 10.1093/Nar/12.4.1779  0.37
1981 Dubnau E, Ramakrishna N, Cabane K, Smith I. Cloning of an early sporulation gene in Bacillus subtilis. Journal of Bacteriology. 147: 622-32. PMID 6167566 DOI: 10.1128/Jb.147.2.622-632.1981  0.341
1980 Smith I, Paress P, Cabane K, Dubnau E. Genetics and physiology of the rel system of Bacillus subtilis. Molecular & General Genetics : Mgg. 178: 271-9. PMID 6248722 DOI: 10.1007/Bf00270472  0.308
1979 Williams G, Smith I. Chromosomal mutations causing resistance to tetracycline in Bacillus subtilis. Molecular & General Genetics : Mgg. 177: 23-9. PMID 119896 DOI: 10.1007/Bf00267249  0.319
1978 Smith I, Paress P, Pestka S. Thiostrepton-resistant mutants exhibit relaxed synthesis of RNA. Proceedings of the National Academy of Sciences of the United States of America. 75: 5993-7. PMID 104297 DOI: 10.1073/Pnas.75.12.5993  0.344
1972 Smith I, Smith H, Pifko S. Preparation and use of RNA-cellulose columns. Analytical Biochemistry. 48: 27-32. PMID 4625254 DOI: 10.1016/0003-2697(72)90166-2  0.309
1971 Smith I, Colli W, Oishi M. Studies on the physical linkage of antibiotic resistance markers to ribosomal RNA genes in Bacillus subtilis Journal of Molecular Biology. 62: 111-119. PMID 5003312 DOI: 10.1016/0022-2836(71)90134-3  0.404
1971 Colli W, Smith I, Oishi M. Physical linkage between 5 s, 16 s and 23 s ribosomal RNA genes in Bacillus subtilis Journal of Molecular Biology. 56: 117-127. PMID 4995655 DOI: 10.1016/0022-2836(71)90088-X  0.339
1965 Dubnau D, Smith I, Morell P, Marmur J. Gene conservation in Bacillus species. I. Conserved genetic and nucleic acid base sequence homologies. Proceedings of the National Academy of Sciences of the United States of America. 54: 491-8. PMID 4956287 DOI: 10.1073/Pnas.54.2.491  0.301
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