| Year |
Citation |
Score |
| 2019 |
Ajasin DO, Rao VR, Wu X, Ramasamy S, Pujato M, Ruiz AP, Fiser A, Bresnick AR, Kalpana GV, Prasad VR. CCL2 mobilizes ALIX to facilitate Gag-p6 mediated HIV-1 virion release. Elife. 8. PMID 31172941 DOI: 10.7554/Elife.35546 |
0.578 |
|
| 2019 |
Ruiz AP, Ajasin DO, Ramasamy S, DesMarais V, Eugenin EA, Prasad VR. A Naturally Occurring Polymorphism in the HIV-1 Tat Basic Domain Inhibits Uptake by Bystander Cells and Leads to Reduced Neuroinflammation. Scientific Reports. 9: 3308. PMID 30824746 DOI: 10.1038/S41598-019-39531-5 |
0.526 |
|
| 2018 |
Ajasin DO, Rao VR, Wu X, Ramasamy S, Pujato M, Ruiz AP, Fiser A, Bresnick AR, Kalpana GV, Prasad VR. Author response: CCL2 mobilizes ALIX to facilitate Gag-p6 mediated HIV-1 virion release Elife. DOI: 10.7554/Elife.35546.047 |
0.463 |
|
| 2017 |
Kuniholm MH, Liang H, Anastos K, Gustafson D, Kassaye S, Nowicki M, Sha BE, Pawlowski EJ, Gange SJ, Aouizerat BE, Pushkarsky T, Bukrinsky MI, Prasad VR. Association of a 3' untranslated region polymorphism in proprotein convertase subtilisin/kexin type 9 with HIV viral load and CD4+ levels in HIV/hepatitis C virus coinfected women. Aids (London, England). 31: 2483-2492. PMID 29120899 DOI: 10.1097/Qad.0000000000001648 |
0.518 |
|
| 2017 |
Prasad VR, Kalpana GV. FISHing Out the Hidden Enemy: Advances in Detecting and Measuring Latent HIV-Infected Cells. Mbio. 8. PMID 28928214 DOI: 10.1128/Mbio.01433-17 |
0.456 |
|
| 2017 |
Kuniholm MH, Liang H, Anastos K, Gustafson D, Kassaye S, Nowicki M, Sha BE, Pawlowski EJ, Gange SJ, Aouizerat BE, Pushkarsky T, Bukrinsky MI, Prasad VR. Association of a 3' Untranslated Region Polymorphism in PCSK9 with HIV Viral Load and CD4+ Levels in HIV/Hepatitis C Virus Co-Infected Women. Aids (London, England). PMID 28926398 DOI: 10.1097/QAD.0000000000001648 |
0.396 |
|
| 2016 |
Rao VR, Eugenin EA, Prasad VR. Evaluating the Role of Viral Proteins in HIV-Mediated Neurotoxicity Using Primary Human Neuronal Cultures. Methods in Molecular Biology (Clifton, N.J.). 1354: 367-76. PMID 26714725 DOI: 10.1007/978-1-4939-3046-3_25 |
0.434 |
|
| 2016 |
Ruiz AP, Prasad VR. Measuring the Uptake and Transactivation Function of HIV-1 Tat Protein in a Trans-cellular Cocultivation Setup. Methods in Molecular Biology (Clifton, N.J.). 1354: 353-66. PMID 26714724 DOI: 10.1007/978-1-4939-3046-3_24 |
0.451 |
|
| 2015 |
Dara J, Dow A, Cromwell E, Sturdevant CB, Mallewa M, Swanstrom R, Van Rie A, Prasad VR. Multivariable analysis to determine if HIV-1 Tat dicysteine motif is associated with neurodevelopmental delay in HIV-infected children in Malawi. Behavioral and Brain Functions : Bbf. 11: 38. PMID 26678821 DOI: 10.1186/S12993-015-0083-7 |
0.508 |
|
| 2015 |
G Aralaguppe SP, Sharma S, Menon M, Prasad VR, Saravanan S, Murugavel KG, Solomon S, Ranga U. The evolving profile of the signature amino acid residues in HIV-1 subtype C Tat. Aids Research and Human Retroviruses. PMID 26678403 DOI: 10.1089/Aid.2015.0208 |
0.42 |
|
| 2015 |
Duclair S, Gautam A, Ellington A, Prasad VR. High-affinity RNA Aptamers Against the HIV-1 Protease Inhibit Both In Vitro Protease Activity and Late Events of Viral Replication. Molecular Therapy. Nucleic Acids. 4: e228. PMID 25689224 DOI: 10.1038/Mtna.2015.1 |
0.801 |
|
| 2014 |
Garforth SJ, Lwatula C, Prasad VR. The lysine 65 residue in HIV-1 reverse transcriptase function and in nucleoside analog drug resistance. Viruses. 6: 4080-94. PMID 25341667 DOI: 10.3390/V6104080 |
0.815 |
|
| 2014 |
Rao VR, Neogi U, Eugenin E, Prasad VR. The gp120 protein is a second determinant of decreased neurovirulence of Indian HIV-1C isolates compared to southern African HIV-1C isolates. Plos One. 9: e107074. PMID 25188269 DOI: 10.1371/Journal.Pone.0107074 |
0.488 |
|
| 2014 |
Neogi U, Rao SD, Bontell I, Verheyen J, Rao VR, Gore SC, Soni N, Shet A, Schülter E, Ekstrand ML, Wondwossen A, Kaiser R, Madhusudhan MS, Prasad VR, Sonnerborg A. Novel tetra-peptide insertion in Gag-p6 ALIX-binding motif in HIV-1 subtype C associated with protease inhibitor failure in Indian patients. Aids (London, England). 28: 2319-22. PMID 25102091 DOI: 10.1097/Qad.0000000000000419 |
0.529 |
|
| 2014 |
Prasad VR, Bukrinsky MI. New clues to understanding HIV nonprogressors: low cholesterol blocks HIV trans infection. Mbio. 5: e01396-14. PMID 24917601 DOI: 10.1128/Mbio.01396-14 |
0.461 |
|
| 2014 |
Rao VR, Ruiz AP, Prasad VR. Viral and cellular factors underlying neuropathogenesis in HIV associated neurocognitive disorders (HAND). Aids Research and Therapy. 11: 13. PMID 24894206 DOI: 10.1186/1742-6405-11-13 |
0.487 |
|
| 2014 |
Shaked I, Hanna DB, Gleißner C, Marsh B, Plants J, Tracy D, Anastos K, Cohen M, Golub ET, Karim R, Lazar J, Prasad V, Tien PC, Young MA, Landay AL, et al. Macrophage inflammatory markers are associated with subclinical carotid artery disease in women with human immunodeficiency virus or hepatitis C virus infection. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1085-92. PMID 24651679 DOI: 10.1161/Atvbaha.113.303153 |
0.357 |
|
| 2014 |
Hanna LE, Neogi U, Ranga U, Swaminathan S, Prasad VR. Phylogenetic characterization of six full-length HIV-1 subtype C molecular clones from three patients: identification of rare subtype C strains containing two NF-κB motifs in the long terminal repeat. Aids Research and Human Retroviruses. 30: 586-91. PMID 24387762 DOI: 10.1089/Aid.2013.0275 |
0.528 |
|
| 2013 |
Mathew S, Nguyen M, Wu X, Pal A, Shah VB, Prasad VR, Aiken C, Kalpana GV. INI1/hSNF5-interaction defective HIV-1 IN mutants exhibit impaired particle morphology, reverse transcription and integration in vivo. Retrovirology. 10: 66. PMID 23799881 DOI: 10.1186/1742-4690-10-66 |
0.579 |
|
| 2013 |
Rao VR, Neogi U, Talboom JS, Padilla L, Rahman M, Fritz-French C, Gonzalez-Ramirez S, Verma A, Wood C, Ruprecht RM, Ranga U, Azim T, Joska J, Eugenin E, Shet A, ... ... Prasad VR, et al. Clade C HIV-1 isolates circulating in Southern Africa exhibit a greater frequency of dicysteine motif-containing Tat variants than those in Southeast Asia and cause increased neurovirulence. Retrovirology. 10: 61. PMID 23758766 DOI: 10.1186/1742-4690-10-61 |
0.541 |
|
| 2012 |
Lwatula C, Garforth SJ, Prasad VR. Lys66 residue as a determinant of high mismatch extension and misinsertion rates of HIV-1 reverse transcriptase. The Febs Journal. 279: 4010-24. PMID 22925131 DOI: 10.1111/J.1742-4658.2012.08807.X |
0.843 |
|
| 2012 |
Kim J, Wang L, Li Y, Becnel KD, Frey KM, Garforth SJ, Prasad VR, Schinazi RF, Liotta DC, Anderson KS. Pre-steady state kinetic analysis of cyclobutyl derivatives of 2′-deoxyadenosine 5′-triphosphate as inhibitors of HIV-1 reverse transcriptase Bioorganic and Medicinal Chemistry Letters. 22: 4064-4067. PMID 22595174 DOI: 10.1016/J.Bmcl.2012.04.078 |
0.583 |
|
| 2012 |
Neogi U, Gupta S, Sahoo PN, Shet A, Rao SD, Ranga U, Prasad VR. Genetic characterization of HIV type 1 Tat exon 1 from a southern Indian clinical cohort: identification of unique epidemiological signature residues. Aids Research and Human Retroviruses. 28: 1152-6. PMID 22236201 DOI: 10.1089/Aid.2011.0380 |
0.549 |
|
| 2011 |
Ramalingam D, Duclair S, Datta SA, Ellington A, Rein A, Prasad VR. RNA aptamers directed to human immunodeficiency virus type 1 Gag polyprotein bind to the matrix and nucleocapsid domains and inhibit virus production. Journal of Virology. 85: 305-14. PMID 20980522 DOI: 10.1128/Jvi.02626-09 |
0.772 |
|
| 2010 |
Garforth SJ, Domaoal RA, Lwatula C, Landau MJ, Meyer AJ, Anderson KS, Prasad VR. K65R and K65A substitutions in HIV-1 reverse transcriptase enhance polymerase fidelity by decreasing both dNTP misinsertion and mispaired primer extension efficiencies. Journal of Molecular Biology. 401: 33-44. PMID 20538005 DOI: 10.1016/J.Jmb.2010.06.001 |
0.82 |
|
| 2010 |
Drosopoulos WC, Prasad VR. The telomerase-specific T motif is a restrictive determinant of repetitive reverse transcription by human telomerase. Molecular and Cellular Biology. 30: 447-59. PMID 19917726 DOI: 10.1128/Mcb.00853-09 |
0.396 |
|
| 2009 |
Rao VR, Eugenin EA, Berman JW, Prasad VR. Methods to study monocyte migration induced by HIV-infected cells. Methods in Molecular Biology (Clifton, N.J.). 485: 295-309. PMID 19020833 DOI: 10.1007/978-1-59745-170-3_20 |
0.515 |
|
| 2009 |
Mandal D, Prasad VR. Analysis of 2-LTR circle junctions of viral DNA in infected cells. Methods in Molecular Biology (Clifton, N.J.). 485: 73-85. PMID 19020819 DOI: 10.1007/978-1-59745-170-3_6 |
0.486 |
|
| 2008 |
Rao VR, Sas AR, Eugenin EA, Siddappa NB, Bimonte-Nelson H, Berman JW, Ranga U, Tyor WR, Prasad VR. HIV-1 clade-specific differences in the induction of neuropathogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10010-6. PMID 18829958 DOI: 10.1523/Jneurosci.2955-08.2008 |
0.551 |
|
| 2008 |
Garforth SJ, Parniak MA, Prasad VR. Utilization of a deoxynucleoside diphosphate substrate by HIV reverse transcriptase. Plos One. 3: e2074. PMID 18446195 DOI: 10.1371/Journal.Pone.0002074 |
0.631 |
|
| 2008 |
Silverman AP, Garforth SJ, Prasad VR, Kool ET. Probing the active site steric flexibility of HIV-1 reverse transcriptase: different constraints for DNA- versus RNA-templated synthesis. Biochemistry. 47: 4800-7. PMID 18366188 DOI: 10.1021/Bi702427Y |
0.512 |
|
| 2008 |
Dash PK, Siddappa NB, Mangaiarkarasi A, Mahendarkar AV, Roshan P, Anand KK, Mahadevan A, Satishchandra P, Shankar SK, Prasad VR, Ranga U. Exceptional molecular and coreceptor-requirement properties of molecular clones isolated from an Human Immunodeficiency Virus Type-1 subtype C infection. Retrovirology. 5: 25. PMID 18328091 DOI: 10.1186/1742-4690-5-25 |
0.486 |
|
| 2007 |
Braun SE, Shi X, Qiu G, Wong FE, Joshi PJ, Prasad VR, Johnson RP. Instability of retroviral vectors with HIV-1-specific RT aptamers due to cryptic splice sites in the U6 promoter. Aids Research and Therapy. 4: 24. PMID 17941994 DOI: 10.1186/1742-6405-4-24 |
0.472 |
|
| 2007 |
Drosopoulos WC, Prasad VR. The active site residue Valine 867 in human telomerase reverse transcriptase influences nucleotide incorporation and fidelity. Nucleic Acids Research. 35: 1155-68. PMID 17264120 DOI: 10.1093/Nar/Gkm002 |
0.544 |
|
| 2007 |
Garforth SJ, Kim TW, Parniak MA, Kool ET, Prasad VR. Site-directed mutagenesis in the fingers subdomain of HIV-1 reverse transcriptase reveals a specific role for the beta3-beta4 hairpin loop in dNTP selection. Journal of Molecular Biology. 365: 38-49. PMID 17055529 DOI: 10.1016/J.Jmb.2006.09.057 |
0.556 |
|
| 2006 |
Dash C, Fisher TS, Prasad VR, Le Grice SF. Examining interactions of HIV-1 reverse transcriptase with single-stranded template nucleotides by nucleoside analog interference. The Journal of Biological Chemistry. 281: 27873-81. PMID 16867979 DOI: 10.1074/Jbc.M603970200 |
0.674 |
|
| 2006 |
Mandal D, Dash C, Le Grice SF, Prasad VR. Analysis of HIV-1 replication block due to substitutions at F61 residue of reverse transcriptase reveals additional defects involving the RNase H function. Nucleic Acids Research. 34: 2853-63. PMID 16723431 DOI: 10.1093/Nar/Gkl360 |
0.599 |
|
| 2006 |
Aravindhan V, Narayanan S, Gautham N, Prasad V, Kannan P, Jacobs WR, Narayanan P. T-h-2 immunity and CD3+CD45RBlow-activated T cells in mice immunized with recombinant bacillus Calmette-Guérin expressing HIV-1 principal neutralizing determinant epitope. Fems Immunology and Medical Microbiology. 47: 45-55. PMID 16706787 DOI: 10.1111/J.1574-695X.2006.00061.X |
0.344 |
|
| 2006 |
Garforth SJ, Wu YY, Prasad VR. Structural features of mouse telomerase RNA are responsible for the lower activity of mouse telomerase versus human telomerase. The Biochemical Journal. 397: 399-406. PMID 16669789 DOI: 10.1042/Bj20060456 |
0.374 |
|
| 2006 |
Curr K, Tripathi S, Lennerstrand J, Larder BA, Prasad VR. Influence of naturally occurring insertions in the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase on polymerase fidelity and mutation frequencies in vitro. The Journal of General Virology. 87: 419-28. PMID 16432030 DOI: 10.1099/Vir.0.81458-0 |
0.817 |
|
| 2006 |
Hamburgh ME, Curr KA, Monaghan M, Rao VR, Tripathi S, Preston BD, Sarafianos S, Arnold E, Darden T, Prasad VR. Structural determinants of slippage-mediated mutations by human immunodeficiency virus type 1 reverse transcriptase. The Journal of Biological Chemistry. 281: 7421-8. PMID 16423828 DOI: 10.1074/Jbc.M511380200 |
0.814 |
|
| 2005 |
Fisher TS, Joshi P, Prasad VR. HIV-1 reverse transcriptase mutations that confer decreased in vitro susceptibility to anti-RT DNA aptamer RT1t49 confer cross resistance to other anti-RT aptamers but not to standard RT inhibitors. Aids Research and Therapy. 2: 8. PMID 16207371 DOI: 10.1186/1742-6405-2-8 |
0.752 |
|
| 2005 |
Drosopoulos WC, Direnzo R, Prasad VR. Human telomerase RNA template sequence is a determinant of telomere repeat extension rate. The Journal of Biological Chemistry. 280: 32801-10. PMID 16061476 DOI: 10.1074/Jbc.M506319200 |
0.375 |
|
| 2005 |
Joshi PJ, North TW, Prasad VR. Aptamers directed to HIV-1 reverse transcriptase display greater efficacy over small hairpin RNAs targeted to viral RNA in blocking HIV-1 replication. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 677-86. PMID 15851006 DOI: 10.1016/J.Ymthe.2005.01.013 |
0.585 |
|
| 2004 |
Rezende LF, Prasad VR. Nucleoside-analog resistance mutations in HIV-1 reverse transcriptase and their influence on polymerase fidelity and viral mutation rates. The International Journal of Biochemistry & Cell Biology. 36: 1716-34. PMID 15183340 DOI: 10.1016/J.Biocel.2004.02.025 |
0.627 |
|
| 2004 |
Hehl EA, Joshi P, Kalpana GV, Prasad VR. Interaction between human immunodeficiency virus type 1 reverse transcriptase and integrase proteins. Journal of Virology. 78: 5056-67. PMID 15113887 DOI: 10.1128/Jvi.78.10.5056-5067.2004 |
0.785 |
|
| 2004 |
Ranga U, Shankarappa R, Siddappa NB, Ramakrishna L, Nagendran R, Mahalingam M, Mahadevan A, Jayasuryan N, Satishchandra P, Shankar SK, Prasad VR. Tat protein of human immunodeficiency virus type 1 subtype C strains is a defective chemokine. Journal of Virology. 78: 2586-90. PMID 14963162 DOI: 10.1128/Jvi.78.5.2586-2590.2004 |
0.478 |
|
| 2003 |
Joshi PJ, Fisher TS, Prasad VR. Anti-HIV inhibitors based on nucleic acids: emergence of aptamers as potent antivirals. Current Drug Targets. Infectious Disorders. 3: 383-400. PMID 14754437 DOI: 10.2174/1568005033481060 |
0.707 |
|
| 2003 |
Fisher TS, Darden T, Prasad VR. Mutations proximal to the minor groove-binding track of human immunodeficiency virus type 1 reverse transcriptase differentially affect utilization of RNA versus DNA as template. Journal of Virology. 77: 5837-45. PMID 12719577 DOI: 10.1128/Jvi.77.10.5837-5845.2003 |
0.673 |
|
| 2003 |
Fisher TS, Darden T, Prasad VR. Substitutions at Phe61 in the beta3-beta4 hairpin of HIV-1 reverse transcriptase reveal a role for the Fingers subdomain in strand displacement DNA synthesis. Journal of Molecular Biology. 325: 443-59. PMID 12498795 DOI: 10.1016/S0022-2836(02)01225-1 |
0.699 |
|
| 2002 |
Joshi P, Prasad VR. Potent inhibition of human immunodeficiency virus type 1 replication by template analog reverse transcriptase inhibitors derived by SELEX (systematic evolution of ligands by exponential enrichment). Journal of Virology. 76: 6545-57. PMID 12050367 DOI: 10.1128/Jvi.76.13.6545-6557.2002 |
0.586 |
|
| 2002 |
Fisher TS, Prasad VR. Substitutions of Phe61 located in the vicinity of template 5'-overhang influence polymerase fidelity and nucleoside analog sensitivity of HIV-1 reverse transcriptase. The Journal of Biological Chemistry. 277: 22345-52. PMID 11948182 DOI: 10.1074/Jbc.M200282200 |
0.73 |
|
| 2002 |
Fisher TS, Joshi P, Prasad VR. Mutations that confer resistance to template-analog inhibitors of human immunodeficiency virus (HIV) type 1 reverse transcriptase lead to severe defects in HIV replication. Journal of Virology. 76: 4068-72. PMID 11907245 DOI: 10.1128/Jvi.76.8.4068-4072.2002 |
0.749 |
|
| 2001 |
Rezende LF, Kew Y, Prasad VR. The Effect of Increased Processivity on Overall Fidelity of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Journal of Biomedical Science. 8: 197-205. DOI: 10.1159/000054033 |
0.621 |
|
| 2000 |
Shah FS, Curr KA, Hamburgh ME, Parniak M, Mitsuya H, Arnez JG, Prasad VR. Differential influence of nucleoside analog-resistance mutations K65R and L74V on the overall mutation rate and error specificity of human immunodeficiency virus type 1 reverse transcriptase. The Journal of Biological Chemistry. 275: 27037-44. PMID 10833521 DOI: 10.1074/Jbc.M002881200 |
0.804 |
|
| 1999 |
Lin JH, Makris A, McMahon C, Bear SE, Patriotis C, Prasad VR, Brent R, Golemis EA, Tsichlis PN. The ankyrin repeat-containing adaptor protein Tvl-1 is a novel substrate and regulator of Raf-1 Journal of Biological Chemistry. 274: 14706-14715. PMID 10329666 DOI: 10.1074/Jbc.274.21.14706 |
0.303 |
|
| 1999 |
Wu X, Liu H, Xiao H, Conway JA, Hehl E, Kalpana GV, Prasad V, Kappes JC. Human immunodeficiency virus type 1 integrase protein promotes reverse transcription through specific interactions with the nucleoprotein reverse transcription complex Journal of Virology. 73: 2126-2135. PMID 9971795 DOI: 10.1128/Jvi.73.3.2126-2135.1999 |
0.793 |
|
| 1998 |
Hamburgh ME, Drosopoulos WC, Prasad VR. The influence of 3TC-resistance mutations E89G and M184V in the human immunodeficiency virus reverse transcriptase on mispair extension efficiency. Nucleic Acids Research. 26: 4389-94. PMID 9742239 DOI: 10.1093/Nar/26.19.4389 |
0.844 |
|
| 1998 |
Drosopoulos WC, Rezende LF, Wainberg MA, Prasad VR. Virtues of being faithful: can we limit the genetic variation in human immunodeficiency virus? Journal of Molecular Medicine (Berlin, Germany). 76: 604-12. PMID 9725762 DOI: 10.1007/S001090050257 |
0.6 |
|
| 1998 |
Rezende LF, Drosopoulos WC, Prasad VR. The influence of 3TC resistance mutation M184I on the fidelity and error specificity of human immunodeficiency virus type 1 reverse transcriptase. Nucleic Acids Research. 26: 3066-72. PMID 9611256 DOI: 10.1093/Nar/26.12.3066 |
0.644 |
|
| 1998 |
Kew Y, Olsen LR, Japour AJ, Prasad VR. Insertions into the beta3-beta4 hairpin loop of HIV-1 reverse transcriptase reveal a role for fingers subdomain in processive polymerization. The Journal of Biological Chemistry. 273: 7529-37. PMID 9516454 DOI: 10.1074/Jbc.273.13.7529 |
0.554 |
|
| 1998 |
Hsu M, Inouye P, Rezende L, Richard N, Li Z, Prasad VR, Wainberg MA. Higher fidelity of RNA-dependent DNA mispair extension by M184V drug-resistant than wild-type reverse transcriptase of human immunodeficiency virus type 1. Nucleic Acids Research. 25: 4532-6. PMID 9358162 DOI: 10.1093/Nar/25.22.4532 |
0.585 |
|
| 1998 |
Drosopoulos WC, Prasad VR. Increased Misincorporation Fidelity Observed for Nucleoside Analog Resistance Mutations M184V and E89G in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Does Not Correlate with the Overall Error Rate Measured In Vitro Journal of Virology. 72: 4224-4230. DOI: 10.1128/Jvi.72.5.4224-4230.1998 |
0.614 |
|
| 1998 |
Rezende LF, Curr K, Ueno T, Mitsuya H, Prasad VR. The Impact of Multidideoxynucleoside Resistance-Conferring Mutations in Human Immunodeficiency Virus Type 1 Reverse Transcriptase on Polymerase Fidelity and Error Specificity Journal of Virology. 72: 2890-2895. DOI: 10.1128/Jvi.72.4.2890-2895.1998 |
0.857 |
|
| 1997 |
Mak J, Khorchid A, Cao Q, Huang Y, Lowy I, Parniak MA, Prasad VR, Wainberg MA, Kleiman L. Effects of mutations in Pr160gag-pol upon tRNA(Lys3) and Pr160gag-plo incorporation into HIV-1. Journal of Molecular Biology. 265: 419-31. PMID 9034361 DOI: 10.1006/Jmbi.1996.0742 |
0.59 |
|
| 1996 |
Prasad VR, Drosopoulos WC, Hamburgh ME. Perspective: research highlights at the Albert Einstein College of Medicine Center for AIDS research. Approaches to control drug resistance in HIV: the role of increased polymerase fidelity. Aids Research and Human Retroviruses. 12: 959-63. PMID 8827210 DOI: 10.1089/Aid.1996.12.959 |
0.79 |
|
| 1996 |
Wainberg MA, Drosopoulos WC, Salomon H, Hsu M, Borkow G, Parniak M, Gu Z, Song Q, Manne J, Islam S, Castriota G, Prasad VR. Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase. Science (New York, N.Y.). 271: 1282-5. PMID 8638110 DOI: 10.1126/Science.271.5253.1282 |
0.62 |
|
| 1996 |
Yang G, Song Q, Charles M, Drosopoulos WC, Arnold E, Prasad VR. Use of chimeric human immunodeficiency virus types 1 and 2 reverse transcriptases for structure-function analysis and for mapping susceptibility to nonnucleoside inhibitors. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association. 11: 326-33. PMID 8601218 DOI: 10.1097/00042560-199604010-00002 |
0.623 |
|
| 1996 |
Drosopoulos WC, Prasad VR. Increased polymerase fidelity of E89G, a nucleoside analog-resistant variant of human immunodeficiency virus type 1 reverse transcriptase. Journal of Virology. 70: 4834-4838. DOI: 10.1128/Jvi.70.7.4834-4838.1996 |
0.534 |
|
| 1996 |
Kew Y, Salomon H, Olsen LR, Wainberg MA, Prasad VR. The nucleoside analog-resistant E89G mutant of human immunodeficiency virus type 1 reverse transcriptase displays a broader cross-resistance that extends to nonnucleoside inhibitors. Antimicrobial Agents and Chemotherapy. 40: 1711-1714. DOI: 10.1128/Aac.40.7.1711 |
0.497 |
|
| 1992 |
Prasad VR, Lowy I, de los Santos T, Chiang L, Goff SP. Isolation and characterization of a dideoxyguanosine triphosphate-resistant mutant of human immunodeficiency virus reverse transcriptase. Proceedings of the National Academy of Sciences of the United States of America. 88: 11363-7. PMID 1722328 DOI: 10.1073/Pnas.88.24.11363 |
0.471 |
|
| 1992 |
Song Q, Yang G, Goff SP, Prasad VR. Mutagenesis of the Glu-89 residue in human immunodeficiency virus type 1 (HIV-1) and HIV-2 reverse transcriptases: effects on nucleoside analog resistance. Journal of Virology. 66: 7568-7571. DOI: 10.1128/Jvi.66.12.7568-7571.1992 |
0.573 |
|
| 1991 |
Prasad VR, Goff SP. Structure-function studies of HIV reverse transcriptase. Annals of the New York Academy of Sciences. 616: 11-21. PMID 1706569 DOI: 10.1111/J.1749-6632.1990.Tb17823.X |
0.516 |
|
| 1990 |
Prasad VR, Myrick K, Haseltine W, Goff SP. Expression of enzymatically active reverse transcriptase of simian immunodeficiency virus in bacteria: sensitivity to nucleotide analogue inhibitors. Virology. 179: 896-900. PMID 1700544 DOI: 10.1016/0042-6822(90)90164-M |
0.458 |
|
| 1989 |
Prasad VR, Goff SP. Linker insertion mutagenesis of the human immunodeficiency virus reverse transcriptase expressed in bacteria: definition of the minimal polymerase domain. Proceedings of the National Academy of Sciences of the United States of America. 86: 3104-8. PMID 2470090 DOI: 10.1073/Pnas.86.9.3104 |
0.446 |
|
| 1988 |
Tanese N, Prasad VR, Goff SP. Structural requirements for bacterial expression of stable, enzymatically active fusion proteins containing the human immunodeficiency virus reverse transcriptase. Dna (Mary Ann Liebert, Inc.). 7: 407-16. PMID 2462482 |
0.352 |
|
| 1987 |
Lazo PA, Prasad V, Tsichlis PN. Splice acceptor site for the env message of Moloney murine leukemia virus Journal of Virology. 61: 2038-2041. PMID 3573155 DOI: 10.1128/Jvi.61.6.2038-2041.1987 |
0.325 |
|
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