Richard A. Laursen - Related publications

1966- Boston University, Boston, MA, United States 
Biochemistry, protein chemistry
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Nguyen AT, Szeto C, Gras S. The pockets guide to HLA class I molecules. Biochemical Society Transactions. 49: 2319-2331. PMID 34581761 DOI: 10.1042/BST20210410   
2021 Monsarrat C, Compain G, André C, Engilberge S, Martiel I, Oliéric V, Wolff P, Brillet K, Landolfo M, Silva da Veiga C, Wagner J, Guichard G, Burnouf DY. Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. Journal of Medicinal Chemistry. PMID 34806883 DOI: 10.1021/acs.jmedchem.1c00918   
2021 Milorey B, Schwalbe H, O'Neill N, Schweitzer-Stenner R. Repeating Aspartic Acid Residues Prefer Turn-like Conformations in the Unfolded State: Implications for Early Protein Folding. The Journal of Physical Chemistry. B. PMID 34619031 DOI: 10.1021/acs.jpcb.1c06472   
2021 Arakawa T, Tokunaga M, Kita Y, Niikura T, Baker RW, Reimer JM, Leschziner AE. Structure Analysis of Proteins and Peptides by Difference Circular Dichroism Spectroscopy. The Protein Journal. PMID 34709521 DOI: 10.1007/s10930-021-10024-7   
2021 Adegawa S, Yamaguchi N, Sato R. The base and root of domain II loops of Cry toxins contribute to binding to Bombyx mori ABC transporter C2. The Febs Journal. PMID 34618400 DOI: 10.1111/febs.16224   
2021 Fumagalli G, Carbajo RJ, Nissink JWM, Tart J, Dou R, Thomas AP, Spring DR. Targeting a Novel KRAS Binding Site: Application of One-Component Stapling of Small (5-6-mer) Peptides. Journal of Medicinal Chemistry. PMID 34787423 DOI: 10.1021/acs.jmedchem.1c01334   
2021 Hussain M, Cummins MC, Endo-Streeter S, Sondek J, Kuhlman B. Designer proteins that competitively inhibit Gα by targeting its effector site. The Journal of Biological Chemistry. 101348. PMID 34715131 DOI: 10.1016/j.jbc.2021.101348   
2021 Cuy-Chaparro L, Bohórquez MD, Arévalo-Pinzón G, Castañeda-Ramírez JJ, Suárez CF, Pabón L, Ordóñez D, Gallego-López GM, Suárez CE, Moreno-Pérez DA, Patarroyo MA. Ligand-Receptor Interaction: AMA-1 Contains Small Regions Governing Bovine Erythrocyte Binding. International Journal of Molecular Sciences. 22. PMID 33450807 DOI: 10.3390/ijms22020714   
2021 Sun Z, Zheng S, Zhao H, Niu Z, Lu Y, Pan Y, Yang Y. To improve the predictions of binding residues with DNA, RNA, carbohydrate, and peptide via multi-task deep neural networks. Ieee/Acm Transactions On Computational Biology and Bioinformatics. PMID 34637380 DOI: 10.1109/TCBB.2021.3118916   
2021 Conseil G, Cole SPC. The First Cytoplasmic Loop in the Core Structure of the ABCC1 (Multidrug Resistance Protein 1; MRP1) Transporter Contains Multiple Amino Acids Essential for Its Expression. International Journal of Molecular Sciences. 22. PMID 34575890 DOI: 10.3390/ijms22189710   
2021 Golysheva EA, Boyle AL, Biondi B, Ruzza P, Kros A, Raap J, Toniolo C, Formaggio F, Dzuba SA. Probing the E/K Peptide Coiled-Coil Assembly by Double Electron-Electron Resonance and Circular Dichroism. Biochemistry. 60: 19-30. PMID 33320519 DOI: 10.1021/acs.biochem.0c00773   
2021 Seok J, Hong J, Park J, Kim KJ. Structural analysis of the peptidoglycan editing factor PdeF from Bacillus cereus ATCC 14579. Biochemical and Biophysical Research Communications. 583: 43-48. PMID 34735878 DOI: 10.1016/j.bbrc.2021.10.051   
2021 Balogh BD, Szunyog G, Lukács M, Szakács B, Sóvágó I, Várnagy K. Thermodynamics and structural characterization of the nickel(II) and zinc(II) complexes of various peptide fragments of tau protein. Dalton Transactions (Cambridge, England : 2003). 50: 14411-14420. PMID 34569575 DOI: 10.1039/d1dt02324a   
2021 Tabandeh S, Lemus CE, Leon L. Deciphering the Role of π-Interactions in Polyelectrolyte Complexes Using Rationally Designed Peptides. Polymers. 13. PMID 34202468 DOI: 10.3390/polym13132074   
2021 Palzkill T, Boragine DM, Huang W, Su LH. Deep Sequencing of a Systematic Peptide Library Reveals Conformationally-Constrained Protein Interface Peptides that Disrupt a Protein-Protein Interaction. Chembiochem : a European Journal of Chemical Biology. PMID 34821011 DOI: 10.1002/cbic.202100504   
2021 Kumar A, Kumar P, Saumya KU, Giri R. Investigating the conformational dynamics of SARS-CoV-2 NSP6 protein with emphasis on non-transmembrane 91-112 & 231-290 regions. Microbial Pathogenesis. 161: 105236. PMID 34648928 DOI: 10.1016/j.micpath.2021.105236   
2021 Catalano C, Al Mughram MH, Guo Y, Kellogg GE. 3D interaction homology: Hydropathic interaction environments of serine and cysteine are strikingly different and their roles adapt in membrane proteins. Current Research in Structural Biology. 3: 239-256. PMID 34693344 DOI: 10.1016/j.crstbi.2021.09.002   
2021 Dawson WM, Martin FJO, Rhys GG, Shelley KL, Brady RL, Woolfson DN. Coiled coils 9-to-5: rational design of α-helical barrels with tunable oligomeric states. Chemical Science. 12: 6923-6928. PMID 34745518 DOI: 10.1039/d1sc00460c   
2021 Mahindra A, Tejeda G, Rossi M, Janha O, Herbert I, Morris C, Morgan DC, Beattie W, Montezano AC, Hudson B, Tobin AB, Bhella D, Touyz RM, Jamieson AG, Baillie GS, et al. Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction. Plos One. 16: e0260283. PMID 34793553 DOI: 10.1371/journal.pone.0260283   
2021 Hallinan JP, Doyle LA, Shen BW, Gewe MM, Takushi B, Kennedy MA, Friend D, Roberts JM, Bradley P, Stoddard BL. Design of functionalised circular tandem repeat proteins with longer repeat topologies and enhanced subunit contact surfaces. Communications Biology. 4: 1240. PMID 34716407 DOI: 10.1038/s42003-021-02766-y   
2021 Chan HTH, Moesser MA, Walters RK, Malla TR, Twidale RM, John T, Deeks HM, Johnston-Wood T, Mikhailov V, Sessions RB, Dawson W, Salah E, Lukacik P, Strain-Damerell C, Owen CD, et al. Discovery of SARS-CoV-2 M peptide inhibitors from modelling substrate and ligand binding. Chemical Science. 12: 13686-13703. PMID 34760153 DOI: 10.1039/d1sc03628a   
2021 Chrustowicz J, Sherpa D, Teyra J, Loke MS, Popowicz GM, Basquin J, Sattler M, Prabu JR, Sidhu SS, Schulman BA. Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases. Journal of Molecular Biology. 434: 167347. PMID 34767800 DOI: 10.1016/j.jmb.2021.167347   
2021 Singh J, Maurya A, Singh PK, Viswanathan V, Ahmad MI, Sharma P, Sharma S, Singh TP. A Peptide Bond from the Inter-lobe Segment in the Bilobal Lactoferrin Acts as a Preferred Site for Cleavage for Serine Proteases to Generate the Perfect C-lobe: Structure of the Pepsin Hydrolyzed Lactoferrin C-lobe at 2.28 Å Resolution. The Protein Journal. PMID 34734372 DOI: 10.1007/s10930-021-10028-3   
2021 Zhao Q, Yuan JJ, Hu F, Qian C, Tian CF, Wang JT, Gao D, Yi W, Wang HB. Isolation, physicochemical, and structure-function relationship of the hydrophobic variant of Fc-fusion proteins that bind to TNF-α receptor, HS002 and HS002A. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1186: 123026. PMID 34781108 DOI: 10.1016/j.jchromb.2021.123026   
2021 He T, Liu J, Wang JP. Development of a Dihydropteroate Synthase-Based Fluorescence Polarization Assay for Detection of Sulfonamides and Studying Its Recognition Mechanism. Journal of Agricultural and Food Chemistry. PMID 34783550 DOI: 10.1021/acs.jafc.1c05674   
2021 Guo S, Zahiri H, Stevens C, Spaanderman DC, Milroy LG, Ottmann C, Brunsveld L, Voets IK, Davies PL. Molecular basis for inhibition of adhesin-mediated bacterial-host interactions through a peptide-binding domain. Cell Reports. 37: 110002. PMID 34788627 DOI: 10.1016/j.celrep.2021.110002   
2021 Morgan BR, Massi F. The Role of Substrate Mediated Allostery in the Catalytic Competency of the Bacterial Oligosaccharyltransferase PglB. Frontiers in Molecular Biosciences. 8: 740904. PMID 34604309 DOI: 10.3389/fmolb.2021.740904   
2021 Correia VG, Trovão F, Pinheiro BA, Brás JLA, Silva LM, Nunes C, Coimbra MA, Liu Y, Feizi T, Fontes CMGA, Mulloy B, Chai W, Carvalho AL, Palma AS. Mapping Molecular Recognition of β1,3-1,4-Glucans by a Surface Glycan-Binding Protein from the Human Gut Symbiont Bacteroides ovatus. Microbiology Spectrum. e0182621. PMID 34817219 DOI: 10.1128/Spectrum.01826-21   
2021 Rübbelke M, Hamilton J, Binder F, Bauer M, King J, Nar H, Zeeb M. Discovery and Structure-Based Optimization of Fragments Binding the Mixed Lineage Kinase Domain-like Protein Executioner Domain. Journal of Medicinal Chemistry. PMID 34672548 DOI: 10.1021/acs.jmedchem.1c00686   
2021 Ho TNT, Lee HS, Swaminathan S, Goodwin L, Rai N, Ushay B, Lewis RJ, Rosengren KJ, Conibear AC. Posttranslational modifications of α-conotoxins: sulfotyrosine and C-terminal amidation stabilise structures and increase acetylcholine receptor binding. Rsc Medicinal Chemistry. 12: 1574-1584. PMID 34671739 DOI: 10.1039/d1md00182e   
2021 Lü Y, Bai J, Tan D, Chen T, Shan A. [The effects of hinge structure on the biological activity of antimicrobial peptides and its application in molecular design: a review]. Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology. 37: 3142-3150. PMID 34622623 DOI: 10.13345/j.cjb.200728   
2021 Lee KH, Chang YC, Chen TF, Juan HF, Tsai HK, Chen CY. Connecting MHC-I-binding motifs with HLA alleles via deep learning. Communications Biology. 4: 1194. PMID 34663927 DOI: 10.1038/s42003-021-02716-8   
2021 Yan XF, Yang C, Wang M, Yong Y, Deng Y, Gao YG. Structural analyses of the AAA+ ATPase domain of the transcriptional regulator GtrR in the BDSF quorum sensing system in Burkholderia cenocepacia. Febs Letters. PMID 34837384 DOI: 10.1002/1873-3468.14244   
2021 Lee WC, Jang A, Lee JY, Kim Y. Structural implication of substrate binding by peptidoglycan remodeling enzyme MepS. Biochemical and Biophysical Research Communications. 583: 178-183. PMID 34741988 DOI: 10.1016/j.bbrc.2021.10.050   
2021 Jiang Z, Xiao SR, Liu R. Dissecting and predicting different types of binding sites in nucleic acids based on structural information. Briefings in Bioinformatics. PMID 34624074 DOI: 10.1093/bib/bbab411   
2021 Huang Q, Ng EY, Li Q, Kang C.  H,  N and  C resonance assignments of the Q61H mutant of human KRAS bound to GDP. Biomolecular Nmr Assignments. PMID 34787842 DOI: 10.1007/s12104-021-10058-z   
2021 Nagata T, Shinya S, Ohnuma T, Fukamizo T. Multi-functionality of a tryptophan residue conserved in substrate-binding groove of GH19 chitinases. Scientific Reports. 11: 2494. PMID 33510258 DOI: 10.1038/s41598-021-81903-3   
2021 Zhang W, Liu M, Dupont RL, Huang K, Yu L, Liu S, Wang X, Wang C. Conservation and Identity Selection of Cationic Residues Flanking the Hydrophobic Regions in Intermediate Filament Superfamily. Frontiers in Chemistry. 9: 752630. PMID 34540811 DOI: 10.3389/fchem.2021.752630   
2021 Yang F, Guo L, Li Y, Wang G, Wang J, Zhang C, Fang GX, Chen X, Liu L, Yan X, Liu Q, Qu C, Xu Y, Xiao P, Zhu Z, et al. Structure, function and pharmacology of human itch receptor complexes. Nature. PMID 34789875 DOI: 10.1038/s41586-021-04077-y   
2021 Lamichhane TR, Ghimire MP. Evaluation of SARS-CoV-2 main protease and inhibitor interactions using dihedral angle distributions and radial distribution function. Heliyon. 7: e08220. PMID 34693066 DOI: 10.1016/j.heliyon.2021.e08220   
2021 Takashima H, Yoshimori A, Honda E, Taguri T, Ozawa J, Kasai M, Shuto S, Takehara D. Visualized and Quantitative Conformational Analysis of Peptidomimetics. Acs Omega. 6: 26601-26612. PMID 34661014 DOI: 10.1021/acsomega.1c03967   
2021 Zegota MM, Müller MA, Lantzberg B, Kizilsavas G, Coelho JAS, Moscariello P, Martínez-Negro M, Morsbach S, Gois PMP, Wagner M, Ng DYW, Kuan SL, Weil T. Dual Stimuli-Responsive Dynamic Covalent Peptide Tags: Toward Sequence-Controlled Release in Tumor-like Microenvironments. Journal of the American Chemical Society. PMID 34632780 DOI: 10.1021/jacs.1c06559   
2021 Hu A, Zhao Q, Chen L, Zhao J, Wang Y, Feng K, Wu L, Xie M, Zhou X, Xiao L, Ming Z, Zhang M, Yao R. Identification of Conserved and Divergent Strigolactone Receptors in Sugarcane Reveals a Key Residue Crucial for Plant Branching Control. Frontiers in Plant Science. 12: 747160. PMID 34858455 DOI: 10.3389/fpls.2021.747160   
2021 Sharma AK, Dyba M, Tonelli M, Smith B, Gillette WK, Esposito D, Nissley DV, McCormick F, Maciag AE. NMR H, C, N backbone resonance assignments of the T35S and oncogenic T35S/Q61L mutants of human KRAS4b in the active, GppNHp-bound conformation. Biomolecular Nmr Assignments. PMID 34686998 DOI: 10.1007/s12104-021-10050-7   
2021 Heyne M, Shirian J, Cohen I, Peleg Y, Radisky ES, Papo N, Shifman JM. Climbing Up and Down Binding Landscapes through Deep Mutational Scanning of Three Homologous Protein-Protein Complexes. Journal of the American Chemical Society. PMID 34609866 DOI: 10.1021/jacs.1c08707   
2021 Zhang J, Wang K, Xue P, Chen X, Bian L. Molecular recognition and interaction between human plasminogen Kringle 5 and voltage-dependent anion channel-1 by biological specificity technologies and molecular dynamic simulation. Biophysical Chemistry. 280: 106710. PMID 34741992 DOI: 10.1016/j.bpc.2021.106710   
2021 Nakayoshi T, Kato K, Kurimoto E, Oda A. Virtual Alanine Scan of the Main Protease Active Site in Severe Acute Respiratory Syndrome Coronavirus 2. International Journal of Molecular Sciences. 22. PMID 34576002 DOI: 10.3390/ijms22189837   
2021 Nguyen TAT, Hoang MH, Luc TT, Dang TKN, Nguyen TMT, Vo TN. Two new -kaurane-type diterpene diastereomers isolated from . Natural Product Research. 1-8. PMID 34736370 DOI: 10.1080/14786419.2021.2000412   
2021 Agarwal N, Jaiswal N, Gulati K, Gangele K, Nagar N, Kumar D, Poluri KM. Molecular Insights into Conformational Heterogeneity and Enhanced Structural Integrity of DNA Binding Protein Hup at Low pH. Biochemistry. PMID 34665609 DOI: 10.1021/acs.biochem.1c00395   
2021 Li H, Dong S, Duan L. Difference in the binding mechanisms of ABT-263/43b with Bcl-xL/Bcl-2: computational perspective on the accurate binding free energy analysis. Journal of Molecular Modeling. 27: 317. PMID 34633547 DOI: 10.1007/s00894-021-04924-9