Gregory G. Freund - Publications

Affiliations: 
University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Immunology, Biochemistry

94 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Towers AE, Oelschlager ML, Juda MB, Jain S, Gainey SJ, Freund GG. HFD refeeding in mice after fasting impairs learning by activating caspase-1 in the brain. Metabolism: Clinical and Experimental. 153989. PMID 31697963 DOI: 10.1016/J.Metabol.2019.153989  0.319
2019 Towers AE, Oelschlager ML, Lorenz M, Gainey SJ, McCusker RH, Krauklis SA, Freund GG. Handling stress impairs learning through a mechanism involving caspase-1 activation and adenosine signaling. Brain, Behavior, and Immunity. PMID 31108171 DOI: 10.1016/J.Bbi.2019.05.025  0.367
2019 Towers A, Jain S, Oelschlager M, Gainey S, Freund G. Abstract # 3164 Memory impairment following high-fat diet refeeding is related to caspase-1 activation and oxidative stress in the amygdala Brain, Behavior, and Immunity. 76: e34. DOI: 10.1016/J.Bbi.2018.11.281  0.352
2018 Towers AE, York JM, Baynard T, Gainey SJ, Freund GG. Mouse Testing Methods in Psychoneuroimmunology 2.0: Measuring Behavioral Responses. Methods in Molecular Biology (Clifton, N.J.). 1781: 221-258. PMID 29705851 DOI: 10.1007/978-1-4939-7828-1_13  0.702
2017 Blackmore S, Hernandez J, Juda M, Ryder E, Freund GG, Johnson RW, Steelman AJ. Influenza infection triggers disease in a genetic model of experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28696309 DOI: 10.1073/Pnas.1620415114  0.478
2017 Towers AE, Oelschlager ML, Patel J, Gainey SJ, McCusker RH, Freund GG. Acute fasting inhibits central caspase-1 activity reducing anxiety-like behavior and increasing novel object and object location recognition. Metabolism: Clinical and Experimental. 71: 70-82. PMID 28521881 DOI: 10.1016/J.Metabol.2017.03.005  0.351
2016 Gainey SJ, Kwakwa KA, Bray JK, Pillote MM, Tir VL, Towers AE, Freund GG. Short-Term High-Fat Diet (HFD) Induced Anxiety-Like Behaviors and Cognitive Impairment Are Improved with Treatment by Glyburide. Frontiers in Behavioral Neuroscience. 10: 156. PMID 27563288 DOI: 10.3389/Fnbeh.2016.00156  0.368
2016 Juda M, Brooks A, Towers A, Freund G, McCusker R, Steelman A. Abstract # 1862 Indoleamine-2,3-dioxgenase 1 (Ido1) protects against viral encephalitis Brain, Behavior, and Immunity. 57: e42. DOI: 10.1016/J.Bbi.2016.07.138  0.312
2016 Towers A, Oelschlager M, Patel J, Freund G. Abstract # 1771 Experimental procedures performed sequentially exert a stress that activates caspase-1 and impairs memory in mice Brain, Behavior, and Immunity. 57: e19. DOI: 10.1016/J.Bbi.2016.07.064  0.331
2015 Moon ML, Joesting JJ, Blevins NA, Lawson MA, Gainey SJ, Towers AE, McNeil LK, Freund GG. IL-4 Knock Out Mice Display Anxiety-Like Behavior. Behavior Genetics. 45: 451-60. PMID 25772794 DOI: 10.1007/S10519-015-9714-X  0.396
2015 Dostal C, Towers A, Gainey S, Freund G, Kelley K, McCusker R. Neuron-derived insulin-like growth factor (IGF)-I is necessary for normal cognition and hedonic activity of mice Brain, Behavior, and Immunity. 49: e50. DOI: 10.1016/J.Bbi.2015.06.183  0.333
2015 Gainey S, Tir V, Pillote M, Freund G. Glyburide administration reduces anxiety-like behaviors and mild cognitive impairment induced by short-term high-fat diet feeding exhibiting a role for the hippocampus and amygdala Brain, Behavior, and Immunity. 49: e19. DOI: 10.1016/J.Bbi.2015.06.083  0.33
2015 Towers AE, Oelschlager M, Patel J, Lawson M, McCusker R, Freund G. Acute calorie restriction modifies cognition and anxiety-like behavior in mice by regulating IL-1β priming and activation within the brain Brain Behavior and Immunity. 49. DOI: 10.1016/J.Bbi.2015.06.079  0.375
2014 Joesting JJ, Moon ML, Gainey SJ, Tisza BL, Blevins NA, Freund GG. Fasting Induces IL-1 Resistance and Free-Fatty Acid-Mediated Up-Regulation of IL-1R2 and IL-1RA. Frontiers in Immunology. 5: 315. PMID 25071776 DOI: 10.3389/Fimmu.2014.00315  0.36
2014 Chiu GS, Darmody PT, Walsh JP, Moon ML, Kwakwa KA, Bray JK, McCusker RH, Freund GG. Adenosine through the A2A adenosine receptor increases IL-1β in the brain contributing to anxiety. Brain, Behavior, and Immunity. 41: 218-31. PMID 24907587 DOI: 10.1016/J.Bbi.2014.05.018  0.406
2014 Towers A, Freund G. 137. Acute calorie restriction as a modulator of anxiety-like behavior Brain, Behavior, and Immunity. 40: e40. DOI: 10.1016/J.Bbi.2014.06.157  0.39
2014 Gainey S, Kwakwa K, Bray J, Pillote M, Freund G. 136. Region-specific differences of high-fat diet induced cognitive impairments between the amygdala and hippocampus Brain, Behavior, and Immunity. 40: e39-e40. DOI: 10.1016/J.Bbi.2014.06.156  0.302
2013 York JM, Blevins NA, McNeil LK, Freund GG. Mouse short- and long-term locomotor activity analyzed by video tracking software. Journal of Visualized Experiments : Jove. PMID 23851627 DOI: 10.3791/50252  0.673
2013 Kaczmarczyk MM, Machaj AS, Chiu GS, Lawson MA, Gainey SJ, York JM, Meling DD, Martin SA, Kwakwa KA, Newman AF, Woods JA, Kelley KW, Wang Y, Miller MJ, Freund GG. Methylphenidate prevents high-fat diet (HFD)-induced learning/memory impairment in juvenile mice. Psychoneuroendocrinology. 38: 1553-64. PMID 23411461 DOI: 10.1016/J.Psyneuen.2013.01.004  0.775
2013 Burton MD, Rytych JL, Freund GG, Johnson RW. Central inhibition of interleukin-6 trans-signaling during peripheral infection reduced neuroinflammation and sickness in aged mice. Brain, Behavior, and Immunity. 30: 66-72. PMID 23354002 DOI: 10.1016/J.Bbi.2013.01.002  0.553
2013 Peters VA, Joesting JJ, Freund GG. IL-1 receptor 2 (IL-1R2) and its role in immune regulation. Brain, Behavior, and Immunity. 32: 1-8. PMID 23195532 DOI: 10.1016/J.Bbi.2012.11.006  0.331
2013 Chiu G, Darmody P, Walsh J, Kwakwa K, Freund G. 25. Adenosine impairs locomotor activity and food intake via the A2A/PKA/KATP channel-dependent activation of caspase 1 Brain, Behavior, and Immunity. 32: e7-e8. DOI: 10.1016/J.Bbi.2013.07.037  0.362
2012 Chiu GS, Chatterjee D, Darmody PT, Walsh JP, Meling DD, Johnson RW, Freund GG. Hypoxia/reoxygenation impairs memory formation via adenosine-dependent activation of caspase 1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 13945-55. PMID 23035103 DOI: 10.1523/Jneurosci.0704-12.2012  0.699
2012 Chen L, Teasdale MT, Kaczmarczyk MM, Freund GG, Miller MJ. Development of a Lactobacillus specific T-RFLP method to determine lactobacilli diversity in complex samples. Journal of Microbiological Methods. 91: 262-8. PMID 22981747 DOI: 10.1016/J.Mimet.2012.08.005  0.744
2012 York JM, Blevins NA, Baynard T, Freund GG. Mouse testing methods in psychoneuroimmunology: an overview of how to measure sickness, depressive/anxietal, cognitive, and physical activity behaviors. Methods in Molecular Biology (Clifton, N.J.). 934: 243-76. PMID 22933150 DOI: 10.1007/978-1-62703-071-7_13  0.7
2012 York JM, McDaniel AW, Blevins NA, Guillet RR, Allison SO, Cengel KA, Freund GG. Individually ventilated cages cause chronic low-grade hypoxia impacting mice hematologically and behaviorally. Brain, Behavior, and Immunity. 26: 951-8. PMID 22561683 DOI: 10.1016/J.Bbi.2012.04.008  0.699
2012 Kaczmarczyk MM, Miller MJ, Freund GG. The health benefits of dietary fiber: beyond the usual suspects of type 2 diabetes mellitus, cardiovascular disease and colon cancer. Metabolism: Clinical and Experimental. 61: 1058-66. PMID 22401879 DOI: 10.1016/J.Metabol.2012.01.017  0.753
2012 York JM, Blevins NA, Meling DD, Peterlin MB, Gridley DS, Cengel KA, Freund GG. The biobehavioral and neuroimmune impact of low-dose ionizing radiation. Brain, Behavior, and Immunity. 26: 218-27. PMID 21958477 DOI: 10.1016/J.Bbi.2011.09.006  0.676
2012 Park MJ, Yoo SW, Choe BS, Dantzer R, Freund GG. Acute hypoglycemia causes depressive-like behaviors in mice. Metabolism: Clinical and Experimental. 61: 229-36. PMID 21820138 DOI: 10.1016/J.Metabol.2011.06.013  0.334
2012 Peters V, Meling D, Kwakwa K, Freund G. 163. Macrophages up-regulate IL-1 receptor type 2 (IL-1R2) gene expression during acute hypoxia Brain, Behavior, and Immunity. 26: S45-S46. DOI: 10.1016/J.Bbi.2012.07.187  0.339
2012 Chiu G, Chatterjee D, Darmody P, Walsh J, Johnson R, Freund G. 144. Adenosine receptor-dependent activation of caspase 1 impairs memory formation after hypoxia/reoxygenation Brain, Behavior, and Immunity. 26: S40. DOI: 10.1016/J.Bbi.2012.07.168  0.545
2012 Moon M, Blevins N, York J, Gainey S, Freund G. 134. Free fatty acids (FFAs) induce sickness behavior via a Toll-like receptor (TLR)4 independent pathway Brain, Behavior, and Immunity. 26: S37. DOI: 10.1016/J.Bbi.2012.07.158  0.724
2012 Joesting J, Blevins N, McNeil L, Chiu G, Gainey S, Nemeth A, Freund G. 104. Interleukin (IL)-4 knockout (KO) mice show anxiety-like behaviors that appear dependent on IL-1 receptor antagonist (RA) Brain, Behavior, and Immunity. 26: S29. DOI: 10.1016/J.Bbi.2012.07.128  0.391
2011 Moon ML, McNeil LK, Freund GG. Macrophages make me sick: how macrophage activation states influence sickness behavior. Psychoneuroendocrinology. 36: 1431-40. PMID 21855222 DOI: 10.1016/J.Psyneuen.2011.07.002  0.316
2011 Lavin DN, Joesting JJ, Chiu GS, Moon ML, Meng J, Dilger RN, Freund GG. Fasting induces an anti-inflammatory effect on the neuroimmune system which a high-fat diet prevents. Obesity (Silver Spring, Md.). 19: 1586-94. PMID 21527899 DOI: 10.1038/Oby.2011.73  0.426
2011 Peters V, Meling D, Chiu G, Freund G. 178. Activation of IL-1R2 by acute hypoxia Brain, Behavior, and Immunity. 25: S230. DOI: 10.1016/J.Bbi.2011.07.181  0.313
2011 Kaczmarczyk M, Machaj A, Martin S, Miller M, Baynard T, Freund G. 140. The effect of a short course high-fat diet on bio-behaviors in juvenile mice Brain, Behavior, and Immunity. 25: S219. DOI: 10.1016/J.Bbi.2011.07.143  0.774
2010 Sherry CL, Kim SS, Dilger RN, Bauer LL, Moon ML, Tapping RI, Fahey GC, Tappenden KA, Freund GG. Sickness behavior induced by endotoxin can be mitigated by the dietary soluble fiber, pectin, through up-regulation of IL-4 and Th2 polarization. Brain, Behavior, and Immunity. 24: 631-40. PMID 20138982 DOI: 10.1016/J.Bbi.2010.01.015  0.38
2010 Lavin D, Joesting J, Chiu G, Moon M, Freund G. Phenotypic characterization of diet-induced obese mice in the fed and fasted states Brain Behavior and Immunity. 24. DOI: 10.1016/J.Bbi.2010.07.232  0.311
2010 Chiu G, Chatterjee D, Johnson R, Freund G. The impact of acute hypoxia on learning and memory Brain, Behavior, and Immunity. 24: S40. DOI: 10.1016/J.Bbi.2010.07.131  0.425
2010 York J, McDaniel A, Blevins N, Guillet R, Allison S, Freund G. Ventilated caging systems can affect mouse behavior Brain, Behavior, and Immunity. 24: S38-S39. DOI: 10.1016/J.Bbi.2010.07.127  0.664
2010 Kaczmarczyk M, Machaj S, Miller M, Freund G. The effect of a short course high-fat diet on behavior in juvenile mice Brain, Behavior, and Immunity. 24: S36. DOI: 10.1016/J.Bbi.2010.07.119  0.774
2009 O'Connor JC, Johnson DR, Freund GG. Psychoneuroimmune implications of type 2 diabetes: redux. Immunology and Allergy Clinics of North America. 29: 339-58. PMID 19389586 DOI: 10.1016/J.Iac.2009.02.004  0.563
2009 Sherry CL, Kim SS, Freund GG. Accelerated recovery from acute hypoxia in obese mice is due to obesity-associated up-regulation of interleukin-1 receptor antagonist. Endocrinology. 150: 2660-7. PMID 19213834 DOI: 10.1210/En.2008-1622  0.376
2009 Sherry CL, Kramer JM, York JM, Freund GG. Behavioral recovery from acute hypoxia is reliant on leptin. Brain, Behavior, and Immunity. 23: 169-75. PMID 18854211 DOI: 10.1016/J.Bbi.2008.09.011  0.716
2009 York J, McDaniel A, Peters V, Lavin D, Freund G. 140. Acute hypoxia causes anhedonia and weight loss in mice, which is absent after a second hypoxic exposure Brain, Behavior, and Immunity. 23: S64. DOI: 10.1016/J.Bbi.2009.06.145  0.671
2009 Sherry C, Kim S, Dilger R, Chung B, Bauer L, Tapping R, Fahey G, Tappenden K, Freund G. 110. Dietary soluble fiber alters Th1/Th2 balance in c57bl/6j mice improving LPS-induced fever and anorexia Brain, Behavior, and Immunity. 23: S55. DOI: 10.1016/J.Bbi.2009.06.115  0.313
2009 Kaczmarczyk M, Lavin D, Miller M, Freund G. 62. The effect of a high fat diet on burrowing behavior in mice over a 12-week period Brain, Behavior, and Immunity. 23: S42. DOI: 10.1016/J.Bbi.2009.06.067  0.772
2008 Park MJ, Guest CB, Barnes MB, Martin J, Ahmad U, York JM, Freund GG. Blocking of beta-2 adrenergic receptors hastens recovery from hypoglycemia-associated social withdrawal. Psychoneuroendocrinology. 33: 1411-8. PMID 18814973 DOI: 10.1016/J.Psyneuen.2008.08.005  0.667
2008 Guest CB, Park MJ, Johnson DR, Freund GG. The implication of proinflammatory cytokines in type 2 diabetes. Frontiers in Bioscience : a Journal and Virtual Library. 13: 5187-94. PMID 18508580 DOI: 10.2741/3074  0.321
2008 Guest CB, Deszo EL, Hartman ME, York JM, Kelley KW, Freund GG. Ca2+/calmodulin-dependent kinase kinase alpha is expressed by monocytic cells and regulates the activation profile. Plos One. 3: e1606. PMID 18270593 DOI: 10.1371/Journal.Pone.0001606  0.761
2008 Dantzer R, O'Connor JC, Freund GG, Johnson RW, Kelley KW. From inflammation to sickness and depression: when the immune system subjugates the brain. Nature Reviews. Neuroscience. 9: 46-56. PMID 18073775 DOI: 10.1038/Nrn2297  0.643
2008 Johnson DR, Sherry CL, York JM, Freund GG. Acute hypoxia, diabetes, and neuroimmune dysregulation: converging mechanisms in the brain. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 14: 235-9. PMID 18000066 DOI: 10.1177/1073858407309544  0.692
2008 Chen J, Buchanan JB, Sparkman NL, Godbout JP, Freund GG, Johnson RW. Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system. Brain, Behavior, and Immunity. 22: 301-11. PMID 17951027 DOI: 10.1016/J.Bbi.2007.08.014  0.67
2008 Lavin D, Sherry C, O’Connor J, Dantzer R, Freund G. 63. Diet-induced obesity causes depressive-like behavior in mice Brain, Behavior, and Immunity. 22: 19. DOI: 10.1016/J.Bbi.2008.04.064  0.326
2008 Sherry C, Kim S, Dilger R, Fahey G, Tappenden K, Freund G. 51. Soluble fiber enhances recovery from LPS-induced social withdrawal in a manner dependent on IL-4 Brain, Behavior, and Immunity. 22: 15. DOI: 10.1016/J.Bbi.2008.04.052  0.311
2007 Strle K, McCusker RH, Tran L, King A, Johnson RW, Freund GG, Dantzer R, Kelley KW. Novel activity of an anti-inflammatory cytokine: IL-10 prevents TNFalpha-induced resistance to IGF-I in myoblasts. Journal of Neuroimmunology. 188: 48-55. PMID 17572510 DOI: 10.1016/J.Jneuroim.2007.05.003  0.543
2007 Guest CB, Hartman ME, O'Connor JC, Chakour KS, Sovari AA, Freund GG. Phagocytosis of cholesteryl ester is amplified in diabetic mouse macrophages and is largely mediated by CD36 and SR-A. Plos One. 2: e511. PMID 17551591 DOI: 10.1371/Journal.Pone.0000511  0.6
2007 O'Connor JC, Sherry CL, Guest CB, Freund GG. Type 2 diabetes impairs insulin receptor substrate-2-mediated phosphatidylinositol 3-kinase activity in primary macrophages to induce a state of cytokine resistance to IL-4 in association with overexpression of suppressor of cytokine signaling-3. Journal of Immunology (Baltimore, Md. : 1950). 178: 6886-93. PMID 17513737 DOI: 10.4049/Jimmunol.178.11.6886  0.645
2007 Lin KI, Johnson DR, Freund GG. LPS-dependent suppression of social exploration is augmented in type 1 diabetic mice. Brain, Behavior, and Immunity. 21: 775-82. PMID 17321107 DOI: 10.1016/J.Bbi.2007.01.004  0.359
2007 Johnson DR, O'Connor JC, Hartman ME, Tapping RI, Freund GG. Acute hypoxia activates the neuroimmune system, which diabetes exacerbates. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 1161-6. PMID 17267571 DOI: 10.1523/Jneurosci.4560-06.2007  0.629
2007 Sherry CL, O'Connor JC, Kramer JM, Freund GG. Augmented lipopolysaccharide-induced TNF-alpha production by peritoneal macrophages in type 2 diabetic mice is dependent on elevated glucose and requires p38 MAPK. Journal of Immunology (Baltimore, Md. : 1950). 178: 663-70. PMID 17202326 DOI: 10.4049/Jimmunol.178.2.663  0.609
2007 Guest CB, Yan G, O'connor JC, Freund GG. Obesity and immunity Psychoneuroimmunology, Two-Volume Set. 2: 993-1011. DOI: 10.1016/B978-012088576-3/50054-X  0.493
2006 Johnson DR, O'Connor JC, Satpathy A, Freund GG. Cytokines in type 2 diabetes. Vitamins and Hormones. 74: 405-41. PMID 17027525 DOI: 10.1016/S0083-6729(06)74017-1  0.598
2006 O'Connor JC, Johnson DR, Freund GG. Psychoneuroimmune implications of type 2 diabetes. Neurologic Clinics. 24: 539-59. PMID 16877123 DOI: 10.1016/J.Ncl.2006.03.001  0.572
2006 Strle K, Broussard SR, McCusker RH, Shen WH, LeCleir JM, Johnson RW, Freund GG, Dantzer R, Kelley KW. C-jun N-terminal kinase mediates tumor necrosis factor-alpha suppression of differentiation in myoblasts. Endocrinology. 147: 4363-73. PMID 16777978 DOI: 10.1210/En.2005-1541  0.502
2006 Strle K, Broussard SR, McCusker RH, Tran L, Johnson RW, Freund GG, Dantzer R, Kelley KW. New function for an old inhibitor: IL-10 ameliorates suppression of myogenesis caused by proinflammatory cytokines Brain, Behavior, and Immunity. 20: 68. DOI: 10.1016/J.Bbi.2006.04.152  0.518
2006 Johnson DR, Beck ML, O’Connor JC, Hartman ME, Tapping RI, Freund GG. Hypoxia-induced neuroimmune activation results in sickness behavior that is mediated by IL-1β Brain, Behavior, and Immunity. 20: 36. DOI: 10.1016/J.Bbi.2006.04.068  0.357
2005 Johnson DR, O'Connor JC, Dantzer R, Freund GG. Inhibition of vagally mediated immune-to-brain signaling by vanadyl sulfate speeds recovery from sickness. Proceedings of the National Academy of Sciences of the United States of America. 102: 15184-9. PMID 16217019 DOI: 10.1073/Pnas.0507191102  0.656
2005 O'Connor JC, Satpathy A, Hartman ME, Horvath EM, Kelley KW, Dantzer R, Johnson RW, Freund GG. IL-1beta-mediated innate immunity is amplified in the db/db mouse model of type 2 diabetes. Journal of Immunology (Baltimore, Md. : 1950). 174: 4991-7. PMID 15814729 DOI: 10.4049/Jimmunol.174.8.4991  0.698
2005 Baum JI, O'Connor JC, Seyler JE, Anthony TG, Freund GG, Layman DK. Leucine reduces the duration of insulin-induced PI 3-kinase activity in rat skeletal muscle. American Journal of Physiology. Endocrinology and Metabolism. 288: E86-91. PMID 15339747 DOI: 10.1152/Ajpendo.00272.2004  0.573
2005 Strle K, Broussard SR, McCusker RH, LeCleir JM, Johnson RW, Freund GG, Dantzer R, Kelley KW. # 133 Cytokine-induced IGF-I resistance in muscle cells is mediated by c-Jun N-terminal kinase Brain, Behavior, and Immunity. 19: e68-e69. DOI: 10.1016/J.Bbi.2005.10.140  0.478
2005 Johnson DR, O’Connor JC, Mack CN, Freund GG. #63 db/db Mice exhibit impaired recovery from hypoxia-induced sickness behavior Brain, Behavior, and Immunity. 19: e33. DOI: 10.1016/J.Bbi.2005.10.069  0.332
2004 Day SJ, O'Shaughnessy DL, O'Connor JC, Freund GG. Additional collection devices used in conjunction with the SurePath Liquid-Based Pap Test broom device do not enhance diagnostic utility. Bmc Women's Health. 4: 6. PMID 15363102 DOI: 10.1186/1472-6874-4-6  0.536
2004 Strle K, Broussard SR, McCusker RH, Shen WH, Johnson RW, Freund GG, Dantzer R, Kelley KW. Proinflammatory cytokine impairment of insulin-like growth factor I-induced protein synthesis in skeletal muscle myoblasts requires ceramide. Endocrinology. 145: 4592-602. PMID 15256490 DOI: 10.1210/En.2003-1749  0.517
2004 Shen WH, Jackson ST, Broussard SR, McCusker RH, Strle K, Freund GG, Johnson RW, Dantzer R, Kelley KW. IL-1beta suppresses prolonged Akt activation and expression of E2F-1 and cyclin A in breast cancer cells. Journal of Immunology (Baltimore, Md. : 1950). 172: 7272-81. PMID 15187102 DOI: 10.4049/Jimmunol.172.12.7272  0.536
2004 Hartman ME, O'Connor JC, Godbout JP, Minor KD, Mazzocco VR, Freund GG. Insulin receptor substrate-2-dependent interleukin-4 signaling in macrophages is impaired in two models of type 2 diabetes mellitus. The Journal of Biological Chemistry. 279: 28045-50. PMID 15123681 DOI: 10.1074/Jbc.M404368200  0.719
2004 Yoon P, Keylock KT, Hartman ME, Freund GG, Woods JA. Macrophage hypo-responsiveness to interferon-γ in aged mice is associated with impaired signaling through Jak-STAT Mechanisms of Ageing and Development. 125: 137-143. PMID 15037019 DOI: 10.1016/J.Mad.2003.11.010  0.325
2004 Shen WH, Yin Y, Broussard SR, McCusker RH, Freund GG, Dantzer R, Kelley KW. Tumor necrosis factor alpha inhibits cyclin A expression and retinoblastoma hyperphosphorylation triggered by insulin-like growth factor-I induction of new E2F-1 synthesis. The Journal of Biological Chemistry. 279: 7438-46. PMID 14681231 DOI: 10.1074/Jbc.M310264200  0.302
2004 Deszo EL, Brake DK, Kelley KW, Freund GG. IL-4-dependent CD86 expression requires JAK/STAT6 activation and is negatively regulated by PKCdelta. Cellular Signalling. 16: 271-80. PMID 14636897 DOI: 10.1016/S0898-6568(03)00137-2  0.773
2003 Broussard SR, McCusker RH, Novakofski JE, Strle K, Shen WH, Johnson RW, Freund GG, Dantzer R, Kelley KW. Cytokine-hormone interactions: tumor necrosis factor alpha impairs biologic activity and downstream activation signals of the insulin-like growth factor I receptor in myoblasts. Endocrinology. 144: 2988-96. PMID 12810554 DOI: 10.1210/En.2003-0087  0.494
2003 O'Connor JC, Freund GG. Vanadate and rapamycin synergistically enhance insulin-stimulated glucose uptake. Metabolism: Clinical and Experimental. 52: 666-74. PMID 12800089 DOI: 10.1016/S0026-0495(03)00026-X  0.579
2002 Day SJ, Deszo EL, Freund GG. Dual sampling of the endocervix and its impact on AutoCyte Prep endocervical adequacy. American Journal of Clinical Pathology. 118: 41-6. PMID 12109854 DOI: 10.1309/U72E-Xd57-Nf4J-Xvg8  0.733
2002 Strle K, Zhou JH, Broussard SR, Venters HD, Johnson RW, Freund GG, Dantzer R, Kelley KW. IL-10 promotes survival of microglia without activating Akt. Journal of Neuroimmunology. 122: 9-19. PMID 11777539 DOI: 10.1016/S0165-5728(01)00444-1  0.544
2002 Godbout JP, Pesavento J, Hartman ME, Manson SR, Freund GG. Methylglyoxal enhances cisplatin-induced cytotoxicity by activating protein kinase Cδ Journal of Biological Chemistry. 277: 2554-2561. PMID 11707430 DOI: 10.1074/Jbc.M100385200  0.561
2001 Strle K, Zhou JH, Shen WH, Broussard SR, Johnson RW, Freund GG, Dantzer R, Kelley KW. Interleukin-10 in the brain. Critical Reviews in Immunology. 21: 427-49. PMID 11942558 DOI: 10.1615/Critrevimmunol.V21.I5.20  0.548
2001 Zhou JH, Broussard SR, Strle K, Freund GG, Johnson RW, Dantzer R, Kelley KW. IL-10 inhibits apoptosis of promyeloid cells by activating insulin receptor substrate-2 and phosphatidylinositol 3'-kinase. Journal of Immunology (Baltimore, Md. : 1950). 167: 4436-42. PMID 11591769 DOI: 10.4049/Jimmunol.167.8.4436  0.552
2001 Venters HD, Broussard SR, Zhou JH, Bluthé RM, Freund GG, Johnson RW, Dantzer R, Kelley KW. Tumor necrosis factorα and insulin-like growth factor-I in the brain: Is the whole greater than the sum of its parts? Journal of Neuroimmunology. 119: 151-165. PMID 11585617 DOI: 10.1016/S0165-5728(01)00388-5  0.467
2001 Deszo EL, Brake DK, Cengel KA, Kelley KW, Freund GG. CD45 negatively regulates monocytic cell differentiation by inhibiting phorbol 12-myristate 13-acetate-dependent activation and tyrosine phosphorylation of protein kinase Cdelta. The Journal of Biological Chemistry. 276: 10212-7. PMID 11124968 DOI: 10.1074/Jbc.M010589200  0.762
2001 Broussard SR, Zhou JH, Venters HD, Bluthé RM, Freund GG, Johnson RW, Dantzer R, Kelley KW. At the interface of environment-immune interactions: Cytokine and growth-factor receptors Journal of Animal Science. 79: E268. DOI: 10.2527/Jas2001.79E-Supple268X  0.445
2000 Schacher DH, VanHoy RW, Liu Q, Arkins S, Dantzer R, Freund GG, Kelley KW. Developmental expression of insulin receptor substrate-2 during dimethylsulfoxide-induced differentiation of human HL-60 cells Journal of Immunology. 164: 113-120. PMID 10605001 DOI: 10.4049/Jimmunol.164.1.113  0.309
1999 Godbout JP, Cengel KA, Cheng SL, Minshall C, Kelley KW, Freund GG. Insulin activates caspase-3 by a phosphatidylinositol 3'-kinase-dependent pathway Cellular Signalling. 11: 15-23. PMID 10206340 DOI: 10.1016/S0898-6568(98)00024-2  0.561
1998 Cengel KA, Godbout JP, Freund GG. Phosphatidylinositol 3@?-kinase is associated with a serine kinase that is activated by okadaic acid Biochemical and Biophysical Research Communications. 242: 513-517. PMID 9464247 DOI: 10.1006/Bbrc.1997.7996  0.542
1998 Godbout JP, Deszo E, Cengel KA, Freund GG. Activation of caspase-3 is required for cisplatinum - Dependent apoptosis Faseb Journal. 12: A778.  0.491
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