Jack David Scott - Publications

2001 Colorado State University, Fort Collins, CO 

9 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Scott JD, DeMong DE, Greshock TJ, Basu K, Dai X, Harris J, Hruza A, Li SW, Lin SI, Liu H, Macala MK, Hu Z, Mei H, Zhang H, Walsh P, et al. Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity. Journal of Medicinal Chemistry. PMID 28245354 DOI: 10.1021/Acs.Jmedchem.7B00045  0.726
2015 Fell MJ, Mirescu C, Basu K, Cheewatrakoolpong B, DeMong DE, Ellis JM, Hyde LA, Lin Y, Markgraf CG, Mei H, Miller M, Poulet FM, Scott JD, Smith MD, Yin Z, et al. MLi-2, a potent, selective and centrally active compound for exploring the therapeutic potential and safety of LRRK2 kinase inhibition. The Journal of Pharmacology and Experimental Therapeutics. PMID 26407721 DOI: 10.1124/Jpet.115.227587  0.726
2002 Scott JD, Williams RM. Chemistry and biology of the tetrahydroisoquinoline antitumor antibiotics. Chemical Reviews. 102: 1669-730. PMID 11996547 DOI: 10.1021/Cr010212U  0.371
2002 Scott JD, Williams RM. Total synthesis of (-)-tetrazomine. Determination of the stereochemistry of tetrazomine and the synthesis and biological activity of tetrazomine analogues. Journal of the American Chemical Society. 124: 2951-6. PMID 11902886 DOI: 10.1021/Ja0174027  0.365
2001 Scott JD, Williams RM. Total Synthesis of (-)-Tetrazomine and Determination of Its Stereochemistry. Angewandte Chemie (International Ed. in English). 40: 1463-1465. PMID 29712345 DOI: 10.1002/1521-3773(20010417)40:8<1463::Aid-Anie1463>3.0.Co;2-8  0.363
2001 Scott JD, Williams RM. Total Synthesis of (-)-Tetrazomine and Determination of Its Stereochemistry This work was supported by the National Institutes of Health (Grant CA85419). We are grateful to Yamanouchi Pharmaceutical Co. for providing a generous gift of natural tetrazomine. Angewandte Chemie (International Ed. in English). 40: 1463-1465. PMID 11317303 DOI: 10.1002/1521-3773(20010417)40:8<1463::AID-ANIE1463>3.0.CO;2-8  0.371
2000 Herberich B, Scott JD, Williams RM. Synthesis of a netropsin conjugate of a water-soluble epi-quinocarcin analogue: the importance of stereochemistry at nitrogen. Bioorganic & Medicinal Chemistry. 8: 523-32. PMID 10732968 DOI: 10.1016/S0968-0896(99)00314-4  0.349
2000 Scott JD, Williams RM. Synthetic studies on tetrazomine: lipase PS resolution of racemic cis-β-hydroxypipecolic acid Tetrahedron Letters. 41: 8413-8416. DOI: 10.1016/S0040-4039(00)01527-6  0.353
1998 Scott JD, Tippie TN, Williams RM. Synthetic studies on tetrazomine: Stereochemical assignment of the β-hydroxypipecolic acid Tetrahedron Letters. 39: 3659-3662. DOI: 10.1016/S0040-4039(98)00642-X  0.355
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