Philip Stork - Publications

Affiliations: 
Vollum Institute Oregon Health and Science University, Portland, OR 
Area:
cAMP signaling, Rap1 signaling

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Rauen KA, Schoyer L, Schill L, Stronach B, Albeck J, Andresen BS, Cavé H, Ellis M, Fruchtman SM, Gelb BD, Gibson CC, Gripp K, Hefner E, Huang WYC, Itkin M, ... ... Stork PJS, et al. Proceedings of the fifth international RASopathies symposium: When development and cancer intersect. American Journal of Medical Genetics. Part A. e40632. PMID 30302932 DOI: 10.1002/Ajmg.A.40632  0.305
2017 Takahashi M, Li Y, Dillon TJ, Kariya Y, Stork PJS. Phosphorylation of the C-Raf N-region promotes Raf dimerization. Molecular and Cellular Biology. PMID 28694330 DOI: 10.1128/MCB.00132-17  0.458
2017 Tillo SE, Xiong WH, Takahashi M, Miao S, Andrade AL, Fortin DA, Yang G, Qin M, Smoody BF, Stork PJS, Zhong H. Liberated PKA Catalytic Subunits Associate with the Membrane via Myristoylation to Preferentially Phosphorylate Membrane Substrates. Cell Reports. 19: 617-629. PMID 28423323 DOI: 10.1016/J.Celrep.2017.03.070  0.359
2016 Takahashi M, Li Y, Dillon TJ, Stork PJ. Phosphorylation of Rap1 by cAMP-dependent protein kinase (PKA) creates a binding site for KSR to sustain ERK activation by cAMP. The Journal of Biological Chemistry. PMID 28003362 DOI: 10.1074/jbc.M116.768986  0.525
2016 Li Y, Dillon TJ, Takahashi M, Earley KT, Stork PJ. PKA-independent Ras activation cooperates with Rap1 to mediate activation of ERKs by cAMP. The Journal of Biological Chemistry. PMID 27531745 DOI: 10.1074/jbc.M116.730978  0.46
2015 Obara Y, Nagasawa R, Nemoto W, Pellegrino MJ, Takahashi M, Habecker BA, Stork PJ, Ichiyanagi O, Ito H, Tomita Y, Ishii K, Nakahata N. ERK5 induces ankrd1 for catecholamine biosynthesis and homeostasis in adrenal medullary cells. Cellular Signalling. PMID 26739108 DOI: 10.1016/J.Cellsig.2015.12.016  0.425
2014 Chattergoon NN, Louey S, Stork PJ, Giraud GD, Thornburg KL. Unexpected maturation of PI3K and MAPK-ERK signaling in fetal ovine cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. 307: H1216-25. PMID 25128174 DOI: 10.1152/Ajpheart.00833.2013  0.472
2013 Hu J, Stites EC, Yu H, Germino EA, Meharena HS, Stork PJ, Kornev AP, Taylor SS, Shaw AS. Allosteric activation of functionally asymmetric RAF kinase dimers. Cell. 154: 1036-46. PMID 23993095 DOI: 10.1016/J.Cell.2013.07.046  0.5
2013 Takahashi M, Dillon TJ, Liu C, Kariya Y, Wang Z, Stork PJ. Protein kinase A-dependent phosphorylation of Rap1 regulates its membrane localization and cell migration. The Journal of Biological Chemistry. 288: 27712-23. PMID 23946483 DOI: 10.1074/jbc.M113.466904  0.424
2013 Li Y, Takahashi M, Stork PJ. Ras-mutant cancer cells display B-Raf binding to Ras that activates extracellular signal-regulated kinase and is inhibited by protein kinase A phosphorylation. The Journal of Biological Chemistry. 288: 27646-57. PMID 23893412 DOI: 10.1074/jbc.M113.463067  0.427
2013 Dillon TJ, Takahashi M, Li Y, Tavisala S, Murray SE, Moran AE, Parker DC, Stork PJ. B-Raf is required for positive selection and survival of DP cells, but not for negative selection of SP cells. International Immunology. 25: 259-69. PMID 23334952 DOI: 10.1093/Intimm/Dxs104  0.438
2012 Chattergoon NN, Louey S, Stork P, Giraud GD, Thornburg KL. Mid-gestation ovine cardiomyocytes are vulnerable to mitotic suppression by thyroid hormone Reproductive Sciences. 19: 642-649. PMID 22421446 DOI: 10.1177/1933719111432860  0.452
2012 Chattergoon NN, Giraud GD, Louey S, Stork P, Fowden AL, Thornburg KL. Thyroid hormone drives fetal cardiomyocyte maturation Faseb Journal. 26: 397-408. PMID 21974928 DOI: 10.1096/Fj.10-179895  0.32
2010 Liu C, Takahashi M, Li Y, Dillon TJ, Kaech S, Stork PJ. The interaction of Epac1 and Ran promotes Rap1 activation at the nuclear envelope. Molecular and Cellular Biology. 30: 3956-69. PMID 20547757 DOI: 10.1128/MCB.00242-10  0.313
2009 Obara Y, Yamauchi A, Takehara S, Nemoto W, Takahashi M, Stork PJ, Nakahata N. ERK5 activity is required for nerve growth factor-induced neurite outgrowth and stabilization of tyrosine hydroxylase in PC12 cells. The Journal of Biological Chemistry. 284: 23564-73. PMID 19581298 DOI: 10.1074/jbc.M109.027821  0.584
2009 Obara Y, Nakahata N, Stork PJ. [cAMP signaling for ERK activation in neuronal cells]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 133: 63-8. PMID 19218743 DOI: JST.JSTAGE/fpj/133.63  0.451
2008 Liu C, Takahashi M, Li Y, Song S, Dillon TJ, Shinde U, Stork PJ. Ras is required for the cyclic AMP-dependent activation of Rap1 via Epac2. Molecular and Cellular Biology. 28: 7109-25. PMID 18824540 DOI: 10.1128/MCB.01060-08  0.321
2007 Obara Y, Horgan AM, Stork PJ. The requirement of Ras and Rap1 for the activation of ERKs by cAMP, PACAP, and KCl in cerebellar granule cells. Journal of Neurochemistry. 101: 470-82. PMID 17254020 DOI: 10.1111/J.1471-4159.2006.04390.X  0.514
2006 Pellegrino MJ, Stork PJ. Sustained activation of extracellular signal-regulated kinase by nerve growth factor regulates c-fos protein stabilization and transactivation in PC12 cells. Journal of Neurochemistry. 99: 1480-93. PMID 17223854 DOI: 10.1111/j.1471-4159.2006.04250.x  0.528
2006 Wang Z, Dillon TJ, Pokala V, Mishra S, Labudda K, Hunter B, Stork PJ. Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation. Molecular and Cellular Biology. 26: 2130-45. PMID 16507992 DOI: 10.1128/MCB.26.6.2130-2145.2006  0.514
2005 Stork PJ, Dillon TJ. Multiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functions. Blood. 106: 2952-61. PMID 16076873 DOI: 10.1182/blood-2005-03-1062  0.521
2005 Dillon TJ, Carey KD, Wetzel SA, Parker DC, Stork PJ. Regulation of the small GTPase Rap1 and extracellular signal-regulated kinases by the costimulatory molecule CTLA-4. Molecular and Cellular Biology. 25: 4117-28. PMID 15870282 DOI: 10.1128/Mcb.25.10.4117-4128.2005  0.421
2005 Mishra S, Smolik SM, Forte MA, Stork PJ. Ras-independent activation of ERK signaling via the torso receptor tyrosine kinase is mediated by Rap1. Current Biology : Cb. 15: 366-70. PMID 15723799 DOI: 10.1016/j.cub.2005.02.022  0.414
2004 Obara Y, Labudda K, Dillon TJ, Stork PJ. PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells. Journal of Cell Science. 117: 6085-94. PMID 15546918 DOI: 10.1242/jcs.01527  0.577
2003 Sundgren NC, Giraud GD, Schultz JM, Lasarev MR, Stork PJ, Thornburg KL. Extracellular signal-regulated kinase and phosphoinositol-3 kinase mediate IGF-1 induced proliferation of fetal sheep cardiomyocytes. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 285: R1481-9. PMID 12947030 DOI: 10.1152/ajpregu.00232.2003  0.377
2003 Dillon TJ, Karpitski V, Wetzel SA, Parker DC, Shaw AS, Stork PJ. Ectopic B-Raf expression enhances extracellular signal-regulated kinase (ERK) signaling in T cells and prevents antigen-presenting cell-induced anergy. The Journal of Biological Chemistry. 278: 35940-9. PMID 12855697 DOI: 10.1074/Jbc.M301506200  0.471
2003 Stork PJ. Does Rap1 deserve a bad Rap? Trends in Biochemical Sciences. 28: 267-75. PMID 12765839 DOI: 10.1016/S0968-0004(03)00087-2  0.393
2003 Horgan AM, Stork PJ. Examining the mechanism of Erk nuclear translocation using green fluorescent protein. Experimental Cell Research. 285: 208-20. PMID 12706116 DOI: 10.1016/S0014-4827(03)00037-5  0.587
2003 Carey KD, Watson RT, Pessin JE, Stork PJ. The requirement of specific membrane domains for Raf-1 phosphorylation and activation. The Journal of Biological Chemistry. 278: 3185-96. PMID 12446733 DOI: 10.1074/Jbc.M207014200  0.456
2002 Schmitt JM, Stork PJ. Galpha and Gbeta gamma require distinct Src-dependent pathways to activate Rap1 and Ras. The Journal of Biological Chemistry. 277: 43024-32. PMID 12221082 DOI: 10.1074/jbc.M204006200  0.506
2002 Stork PJ, Schmitt JM. Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation. Trends in Cell Biology. 12: 258-66. PMID 12074885 DOI: 10.1016/S0962-8924(02)02294-8  0.556
2002 Vaudry D, Stork PJ, Lazarovici P, Eiden LE. Signaling pathways for PC12 cell differentiation: making the right connections. Science (New York, N.Y.). 296: 1648-9. PMID 12040181 DOI: 10.1126/science.1071552  0.516
2002 Schmitt JM, Stork PJ. PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1. Molecular Cell. 9: 85-94. PMID 11804588 DOI: 10.1016/S1097-2765(01)00432-4  0.53
2001 Billiard J, Grewal SS, Lukaesko L, Stork PJ, Rotwein P. Hormonal control of insulin-like growth factor I gene transcription in human osteoblasts: dual actions of cAMP-dependent protein kinase on CCAAT/enhancer-binding protein delta. The Journal of Biological Chemistry. 276: 31238-46. PMID 11390399 DOI: 10.1074/jbc.M103634200  0.387
2001 Schmitt JM, Stork PJ. Cyclic AMP-mediated inhibition of cell growth requires the small G protein Rap1. Molecular and Cellular Biology. 21: 3671-83. PMID 11340161 DOI: 10.1128/MCB.21.11.3671-3683.2001  0.512
2000 Florio T, Thellung S, Arena S, Corsaro A, Bajetto A, Schettini G, Stork PJ. Somatostatin receptor 1 (SSTR1)-mediated inhibition of cell proliferation correlates with the activation of the MAP kinase cascade: role of the phosphotyrosine phosphatase SHP-2. Journal of Physiology, Paris. 94: 239-50. PMID 11088001 DOI: 10.1016/S0928-4257(00)00214-X  0.617
2000 Carey KD, Dillon TJ, Schmitt JM, Baird AM, Holdorf AD, Straus DB, Shaw AS, Stork PJ. CD28 and the tyrosine kinase lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1. Molecular and Cellular Biology. 20: 8409-19. PMID 11046138 DOI: 10.1128/Mcb.20.22.8409-8419.2000  0.47
2000 York RD, Molliver DC, Grewal SS, Stenberg PE, McCleskey EW, Stork PJ. Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1. Molecular and Cellular Biology. 20: 8069-83. PMID 11027277 DOI: 10.1128/MCB.20.21.8069-8083.2000  0.644
2000 Grewal SS, Fass DM, Yao H, Ellig CL, Goodman RH, Stork PJ. Calcium and cAMP signals differentially regulate cAMP-responsive element-binding protein function via a Rap1-extracellular signal-regulated kinase pathway. The Journal of Biological Chemistry. 275: 34433-41. PMID 10950954 DOI: 10.1074/jbc.M004728200  0.558
2000 Schmitt JM, Stork PJ. beta 2-adrenergic receptor activates extracellular signal-regulated kinases (ERKs) via the small G protein rap1 and the serine/threonine kinase B-Raf. The Journal of Biological Chemistry. 275: 25342-50. PMID 10840035 DOI: 10.1074/jbc.M003213200  0.491
2000 Grewal SS, Horgan AM, York RD, Withers GS, Banker GA, Stork PJ. Neuronal calcium activates a Rap1 and B-Raf signaling pathway via the cyclic adenosine monophosphate-dependent protein kinase. The Journal of Biological Chemistry. 275: 3722-8. PMID 10652372 DOI: 10.1074/Jbc.275.5.3722  0.633
1999 Grewal SS, York RD, Stork PJ. Extracellular-signal-regulated kinase signalling in neurons. Current Opinion in Neurobiology. 9: 544-53. PMID 10508738 DOI: 10.1016/S0959-4388(99)00010-0  0.62
1999 Silberbach M, Gorenc T, Hershberger RE, Stork PJ, Steyger PS, Roberts CT. Extracellular signal-regulated protein kinase activation is required for the anti-hypertrophic effect of atrial natriuretic factor in neonatal rat ventricular myocytes. The Journal of Biological Chemistry. 274: 24858-64. PMID 10455158 DOI: 10.1074/Jbc.274.35.24858  0.539
1999 Laderoute KR, Mendonca HL, Calaoagan JM, Knapp AM, Giaccia AJ, Stork PJ. Mitogen-activated protein kinase phosphatase-1 (MKP-1) expression is induced by low oxygen conditions found in solid tumor microenvironments. A candidate MKP for the inactivation of hypoxia-inducible stress-activated protein kinase/c-Jun N-terminal protein kinase activity. The Journal of Biological Chemistry. 274: 12890-7. PMID 10212278 DOI: 10.1074/Jbc.274.18.12890  0.455
1999 Chen T, Cho RW, Stork PJ, Weber MJ. Elevation of cyclic adenosine 3',5'-monophosphate potentiates activation of mitogen-activated protein kinase by growth factors in LNCaP prostate cancer cells. Cancer Research. 59: 213-8. PMID 9892209  0.409
1999 Florio T, Yao H, Carey KD, Dillon TJ, Stork PJ. Somatostatin activation of mitogen-activated protein kinase via somatostatin receptor 1 (SSTR1). Molecular Endocrinology (Baltimore, Md.). 13: 24-37. PMID 9892010 DOI: 10.1210/mend.13.1.0224  0.593
1998 York RD, Yao H, Dillon T, Ellig CL, Eckert SP, McCleskey EW, Stork PJ. Rap1 mediates sustained MAP kinase activation induced by nerve growth factor. Nature. 392: 622-6. PMID 9560161 DOI: 10.1038/33451  0.639
1998 Yao H, York RD, Misra-Press A, Carr DW, Stork PJ. The cyclic adenosine monophosphate-dependent protein kinase (PKA) is required for the sustained activation of mitogen-activated kinases and gene expression by nerve growth factor. The Journal of Biological Chemistry. 273: 8240-7. PMID 9525930 DOI: 10.1074/jbc.273.14.8240  0.651
1997 Vossler MR, Yao H, York RD, Pan MG, Rim CS, Stork PJ. cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway. Cell. 89: 73-82. PMID 9094716  0.654
1997 Hirsch DD, Stork PJ. Mitogen-activated protein kinase phosphatases inactivate stress-activated protein kinase pathways in vivo. The Journal of Biological Chemistry. 272: 4568-75. PMID 9020184 DOI: 10.1074/jbc.272.7.4568  0.569
1997 Magi-Galluzzi C, Mishra R, Fiorentino M, Montironi R, Yao H, Capodieci P, Wishnow K, Kaplan I, Stork PJ, Loda M. Mitogen-activated protein kinase phosphatase 1 is overexpressed in prostate cancers and is inversely related to apoptosis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 76: 37-51. PMID 9010448  0.426
1996 Loda M, Capodieci P, Mishra R, Yao H, Corless C, Grigioni W, Wang Y, Magi-Galluzzi C, Stork PJ. Expression of mitogen-activated protein kinase phosphatase-1 in the early phases of human epithelial carcinogenesis. The American Journal of Pathology. 149: 1553-64. PMID 8909245  0.393
1996 Enslen H, Tokumitsu H, Stork PJ, Davis RJ, Soderling TR. Regulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascade. Proceedings of the National Academy of Sciences of the United States of America. 93: 10803-8. PMID 8855261 DOI: 10.1073/Pnas.93.20.10803  0.537
1996 Florio T, Perrino BA, Stork PJ. Cyclic 3,5 adenoise monophosphate and cyclosporin A inhibit cellular proliferation and serine/threonine protein phosphatase activity in pituitary cells. Endocrinology. 137: 4409-18. PMID 8828502 DOI: 10.1210/endo.137.10.8828502  0.465
1996 Leav I, Galluzzi CM, Ziar J, Stork PJ, Ho SM, Loda M. Mitogen-activated protein kinase and mitogen-activated kinase phosphatase-1 expression in the Noble rat model of sex hormone-induced prostatic dysplasia and carcinoma. Laboratory Investigation; a Journal of Technical Methods and Pathology. 75: 361-70. PMID 8804359  0.484
1996 Vossler MR, Yao H, Stork PJS. Mechanism of cAMP activation of MAP kinase in neuroendocrine cells Journal of Investigative Medicine. 44: 153A.  0.478
1995 Roberson MS, Misra-Press A, Laurance ME, Stork PJ, Maurer RA. A role for mitogen-activated protein kinase in mediating activation of the glycoprotein hormone alpha-subunit promoter by gonadotropin-releasing hormone. Molecular and Cellular Biology. 15: 3531-9. PMID 7791760 DOI: 10.1128/Mcb.15.7.3531  0.435
1995 Misra-Press A, Rim CS, Yao H, Roberson MS, Stork PJ. A novel mitogen-activated protein kinase phosphatase. Structure, expression, and regulation. The Journal of Biological Chemistry. 270: 14587-96. PMID 7782322 DOI: 10.1074/Jbc.270.24.14587  0.542
1995 Yao H, Labudda K, Rim C, Capodieci P, Loda M, Stork PJ. Cyclic adenosine monophosphate can convert epidermal growth factor into a differentiating factor in neuronal cells. The Journal of Biological Chemistry. 270: 20748-53. PMID 7657657 DOI: 10.1074/jbc.270.35.20748  0.494
1995 Pan MG, Wang YH, Hirsch DD, Labudda K, Stork PJ. The Wnt-1 proto-oncogene regulates MAP kinase activation by multiple growth factors in PC12 cells. Oncogene. 11: 2005-12. PMID 7478519  0.516
1994 Florio T, Rim C, Hershberger RE, Loda M, Stork PJ. The somatostatin receptor SSTR1 is coupled to phosphotyrosine phosphatase activity in CHO-K1 cells. Molecular Endocrinology (Baltimore, Md.). 8: 1289-97. PMID 7854346 DOI: 10.1210/mend.8.10.7854346  0.304
1992 Pan MG, Florio T, Stork PJ. G protein activation of a hormone-stimulated phosphatase in human tumor cells. Science (New York, N.Y.). 256: 1215-7. PMID 1350382  0.311
1991 Sevarino KA, Stork P. Multiple preprosomatostatin sorting signals mediate secretion via discrete cAMP- and tetradecanoylphorbolacetate-responsive pathways Journal of Biological Chemistry. 266: 18507-18512. PMID 1680862  0.302
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