| Year |
Citation |
Score |
| 2020 |
Lin L, Metherel AH, Di Miceli M, Liu Z, Sahin C, Fioramonti X, Cummins CL, Layé S, Bazinet RP. Tetracosahexaenoylethanolamide, a novel n-acylethanolamide, is elevated in ischemia and increases neuronal output. Journal of Lipid Research. PMID 32826272 DOI: 10.1194/Jlr.Ra120001024 |
0.322 |
|
| 2019 |
Omeragic A, Kara-Yacoubian N, Kelschenbach J, Sahin C, Cummins CL, Volsky DJ, Bendayan R. Peroxisome Proliferator-Activated Receptor-gamma agonists exhibit anti-inflammatory and antiviral effects in an EcoHIV mouse model. Scientific Reports. 9: 9428. PMID 31263138 DOI: 10.1038/S41598-019-45878-6 |
0.303 |
|
| 2019 |
Magomedova L, Tiefenbach J, Zilberman E, Le Billan F, Voisin V, Saikali M, Boivin V, Robitaille M, Gueroussov S, Irimia M, Ray D, Patel R, Xu C, Jeyasuria P, Bader GD, ... ... Cummins CL, et al. ARGLU1 is a transcriptional coactivator and splicing regulator important for stress hormone signaling and development. Nucleic Acids Research. PMID 30698747 DOI: 10.1093/Nar/Gkz010 |
0.332 |
|
| 2018 |
Tiefenbach J, Magomedova L, Liu J, Reunov AA, Tsai R, Eappen NS, Jockusch RA, Nislow C, Cummins CL, Krause HM. Idebenone and coenzyme Q are novel PPARα/γ ligands, with potential for treatment of fatty liver diseases. Disease Models & Mechanisms. 11. PMID 30171034 DOI: 10.1242/Dmm.034801 |
0.337 |
|
| 2018 |
Rasheed A, Cummins CL. Beyond the Foam Cell: The Role of LXRs in Preventing Atherogenesis. International Journal of Molecular Sciences. 19. PMID 30087224 DOI: 10.3390/Ijms19082307 |
0.335 |
|
| 2018 |
Mohan H, Brandt SL, Kim JH, Wong F, Lai M, Prentice KJ, Al Rijjal D, Magomedova L, Batchuluun B, Burdett E, Bhattacharjee A, Cummins CL, Belsham DD, Cox B, Liu Y, et al. 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid (CMPF) Prevents HFD Induced Insulin Resistance via the Maintenance of Hepatic Lipid Homeostasis. Diabetes, Obesity & Metabolism. PMID 30062833 DOI: 10.1111/Dom.13483 |
0.314 |
|
| 2018 |
Rasheed A, Tsai R, Cummins CL. Loss of the Liver X Receptors Disrupts the Balance of Hematopoietic Populations, With Detrimental Effects on Endothelial Progenitor Cells. Journal of the American Heart Association. 7. PMID 29739800 DOI: 10.1161/Jaha.117.007787 |
0.32 |
|
| 2018 |
Rasheed A, Tsai R, Rayner KJ, Cummins CL. Abstract 623: Activating Liver X Receptors Alters Endothelial Progenitor Cell Differentiation and Enhances the Release of Factors that Reduce Atherosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.623 |
0.318 |
|
| 2017 |
Jongstra-Bilen J, Zhang CX, Wisnicki T, Li MK, White-Alfred S, Ilaalagan R, Ferri DM, Deonarain A, Wan MH, Hyduk SJ, Cummins CL, Cybulsky MI. Oxidized Low-Density Lipoprotein Loading of Macrophages Downregulates TLR-Induced Proinflammatory Responses in a Gene-Specific and Temporal Manner through Transcriptional Control. Journal of Immunology (Baltimore, Md. : 1950). PMID 28784845 DOI: 10.4049/Jimmunol.1601363 |
0.304 |
|
| 2017 |
Raitsin S, Tong J, Kish S, Xu X, Magomedova L, Cummins C, Andreazza AC, Scola G, Baker G, Meyer JH. Subchronic Glucocorticoids, Glutathione Depletion and a Postpartum Model Elevate Monoamine Oxidase A Activity in the Prefrontal Cortex of Rats. Brain Research. PMID 28435083 DOI: 10.1016/J.Brainres.2017.03.032 |
0.324 |
|
| 2017 |
Patel R, Magomedova L, Tsai R, Angers S, Orellana A, Cummins CL. Separating the Anti-Inflammatory and Diabetogenic Effects of Glucocorticoids through LXRβ Antagonism. Endocrinology. PMID 28324010 DOI: 10.1210/En.2017-00094 |
0.347 |
|
| 2016 |
Zeng K, Tian L, Patel R, Shao W, Song Z, Liu L, Manuel J, Ma X, McGilvray I, Cummins CL, Weng J, Jin T. Diet polyphenol curcumin stimulates hepatic Fgf21 production and restores its sensitivity in high fat diet fed male mice. Endocrinology. jc20161596. PMID 27967217 DOI: 10.1210/En.2016-1596 |
0.332 |
|
| 2016 |
Bashiri A, Nesan D, Tavallaee G, Sue-Chue-Lam I, Chien K, Maguire GF, Naples M, Zhang J, Magomedova L, Adeli K, Cummins CL, Ng DS. Cellular cholesterol accumulation modulates high fat high sucrose (HFHS) diet-induced ER stress and hepatic inflammasome activation in the development of non-alcoholic steatohepatitis. Biochimica Et Biophysica Acta. PMID 27090939 DOI: 10.1016/J.Bbalip.2016.04.005 |
0.324 |
|
| 2015 |
Huroy S, Kanawaty A, Magomedova L, Cummins CL, George SR, van der Kooy D, Henderson JT. EphB2 Reverse Signaling Regulates Learned Opiate Tolerance via Hippocampal Function. Behavioural Brain Research. PMID 26408450 DOI: 10.1016/J.Bbr.2015.09.023 |
0.303 |
|
| 2015 |
Ahmed S, Bott D, Gomez A, Tamblyn L, Rasheed A, MacPherson L, Sugamori KS, Cho T, Yang Y, Grant DM, Cummins CL, Matthews J. Loss of the Mono-ADP-Ribosyltransferase, TIPARP, Increases Sensitivity to Dioxin-Induced Steatohepatitis and Lethality. The Journal of Biological Chemistry. PMID 25975270 DOI: 10.1074/Jbc.M115.660100 |
0.329 |
|
| 2015 |
Magomedova L, Cummins CL. Glucocorticoids and Metabolic Control. Handbook of Experimental Pharmacology. PMID 25917083 DOI: 10.1007/164_2015_1 |
0.329 |
|
| 2015 |
Patel R, Bookout AL, Magomedova L, Owen BM, Consiglio GP, Shimizu M, Zhang Y, Mangelsdorf DJ, Kliewer SA, Cummins CL. Glucocorticoids regulate the metabolic hormone FGF21 in a feed-forward loop. Molecular Endocrinology (Baltimore, Md.). 29: 213-23. PMID 25495872 DOI: 10.1210/Me.2014-1259 |
0.362 |
|
| 2014 |
Patel R, Williams-Dautovich J, Cummins CL. Minireview: New molecular mediators of glucocorticoid receptor activity in metabolic tissues Molecular Endocrinology. 28: 999-1011. PMID 24766141 DOI: 10.1210/Me.2014-1062 |
0.348 |
|
| 2014 |
Chow EC, Magomedova L, Quach HP, Patel R, Durk MR, Fan J, Maeng HJ, Irondi K, Anakk S, Moore DD, Cummins CL, Pang KS. Vitamin D receptor activation down-regulates the small heterodimer partner and increases CYP7A1 to lower cholesterol. Gastroenterology. 146: 1048-59. PMID 24365583 DOI: 10.1053/J.Gastro.2013.12.027 |
0.369 |
|
| 2014 |
Patel M, Wang XX, Magomedova L, John R, Rasheed A, Santamaria H, Wang W, Tsai R, Qiu L, Orellana A, Advani A, Levi M, Cummins CL. Liver X receptors preserve renal glomerular integrity under normoglycaemia and in diabetes in mice Diabetologia. 57: 435-446. PMID 24201575 DOI: 10.1007/S00125-013-3095-6 |
0.321 |
|
| 2013 |
Chan GNY, Patel R, Cummins CL, Bendayan R. Induction of P-glycoprotein by antiretroviral drugs in human brain microvessel endothelial cells Antimicrobial Agents and Chemotherapy. 57: 4481-4488. PMID 23836171 DOI: 10.1128/Aac.00486-13 |
0.399 |
|
| 2012 |
Hazra S, Rasheed A, Bhatwadekar A, Wang X, Shaw LC, Patel M, Caballero S, Magomedova L, Solis N, Yan Y, Wang W, Thinschmidt JS, Verma A, Li Q, Levi M, ... Cummins CL, et al. Liver X receptor modulates diabetic retinopathy outcome in a mouse model of streptozotocin-induced diabetes. Diabetes. 61: 3270-9. PMID 22891211 DOI: 10.2337/Db11-1596 |
0.332 |
|
| 2012 |
Wollam J, Magner DB, Magomedova L, Rass E, Shen Y, Rottiers V, Habermann B, Cummins CL, Antebi A. A novel 3-hydroxysteroid dehydrogenase that regulates reproductive development and longevity Plos Biology. 10. PMID 22505847 DOI: 10.1371/Journal.Pbio.1001305 |
0.352 |
|
| 2012 |
Hager L, Li L, Pun H, Liu L, Hossain MA, Maguire GF, Naples M, Baker C, Magomedova L, Tam J, Adeli K, Cummins CL, Connelly PW, Ng DS. Lecithin:cholesterol acyltransferase deficiency protects against cholesterol-induced hepatic endoplasmic reticulum stress in mice. The Journal of Biological Chemistry. 287: 20755-68. PMID 22500017 DOI: 10.1074/Jbc.M112.340919 |
0.332 |
|
| 2011 |
Luciani GM, Magomedova L, Puckrin R, Urbanus ML, Wallace IM, Giaever G, Nislow C, Cummins CL, Roy PJ. Dafadine inhibits DAF-9 to promote dauer formation and longevity of Caenorhabditis elegans. Nature Chemical Biology. 7: 891-3. PMID 22057127 DOI: 10.1038/Nchembio.698 |
0.319 |
|
| 2011 |
Wollam J, Magomedova L, Magner DB, Shen Y, Rottiers V, Motola DL, Mangelsdorf DJ, Cummins CL, Antebi A. The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity. Aging Cell. 10: 879-84. PMID 21749634 DOI: 10.1111/J.1474-9726.2011.00733.X |
0.356 |
|
| 2011 |
Chan GN, Hoque MT, Cummins CL, Bendayan R. Regulation of P-glycoprotein by orphan nuclear receptors in human brain microvessel endothelial cells. Journal of Neurochemistry. 118: 163-75. PMID 21517853 DOI: 10.1111/J.1471-4159.2011.07288.X |
0.421 |
|
| 2011 |
Chow EC, Durk MR, Cummins CL, Pang KS. 1Alpha,25-dihydroxyvitamin D3 up-regulates P-glycoprotein via the vitamin D receptor and not farnesoid X receptor in both fxr(-/-) and fxr(+/+) mice and increased renal and brain efflux of digoxin in mice in vivo. The Journal of Pharmacology and Experimental Therapeutics. 337: 846-59. PMID 21421739 DOI: 10.1124/Jpet.111.179101 |
0.4 |
|
| 2011 |
Patel R, Patel M, Tsai R, Lin V, Bookout AL, Zhang Y, Magomedova L, Li T, Chan JF, Budd C, Mangelsdorf DJ, Cummins CL. LXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice. The Journal of Clinical Investigation. 121: 431-41. PMID 21123945 DOI: 10.1172/Jci41681 |
0.394 |
|
| 2011 |
Schmidt DR, Schmidt S, Holmstrom SR, Makishima M, Yu RT, Cummins CL, Mangelsdorf DJ, Kliewer SA. AKR1B7 is induced by the farnesoid X receptor and metabolizes bile acids. The Journal of Biological Chemistry. 286: 2425-32. PMID 21081494 DOI: 10.1074/Jbc.M110.181230 |
0.366 |
|
| 2011 |
Gottschalk S, Cummins CL, Leibfritz D, Christians U, Benet LZ, Serkova NJ. Age and sex differences in the effects of the immunosuppressants cyclosporine, sirolimus and everolimus on rat brain metabolism. Neurotoxicology. 32: 50-7. PMID 21075140 DOI: 10.1016/J.Neuro.2010.10.006 |
0.47 |
|
| 2009 |
Zhang Y, Chan JF, Cummins CL. Liver X Receptors as Therapeutic Targets for Managing Cholesterol: Implications for Atherosclerosis and Other Inflammatory Conditions. Clinical Lipidology. 4: 29-40. PMID 20852746 DOI: 10.2217/17584299.4.1.29 |
0.363 |
|
| 2008 |
Lee YK, Schmidt DR, Cummins CL, Choi M, Peng L, Zhang Y, Goodwin B, Hammer RE, Mangelsdorf DJ, Kliewer SA. Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis. Molecular Endocrinology (Baltimore, Md.). 22: 1345-56. PMID 18323469 DOI: 10.1210/Me.2007-0565 |
0.4 |
|
| 2007 |
Katona BW, Cummins CL, Ferguson AD, Li T, Schmidt DR, Mangelsdorf DJ, Covey DF. Synthesis, characterization, and receptor interaction profiles of enantiomeric bile acids. Journal of Medicinal Chemistry. 50: 6048-58. PMID 17963371 DOI: 10.1021/Jm0707931 |
0.321 |
|
| 2007 |
Umetani M, Domoto H, Gormley AK, Yuhanna IS, Cummins CL, Javitt NB, Korach KS, Shaul PW, Mangelsdorf DJ. 27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen. Nature Medicine. 13: 1185-92. PMID 17873880 DOI: 10.1038/Nm1641 |
0.346 |
|
| 2007 |
Houten SM, Volle DH, Cummins CL, Mangelsdorf DJ, Auwerx J. In vivo imaging of farnesoid X receptor activity reveals the ileum as the primary bile acid signaling tissue. Molecular Endocrinology (Baltimore, Md.). 21: 1312-23. PMID 17426284 DOI: 10.1210/Me.2007-0113 |
0.35 |
|
| 2007 |
Gerisch B, Rottiers V, Li D, Motola DL, Cummins CL, Lehrach H, Mangelsdorf DJ, Antebi A. A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling. Proceedings of the National Academy of Sciences of the United States of America. 104: 5014-9. PMID 17360327 DOI: 10.1073/Pnas.0700847104 |
0.334 |
|
| 2007 |
Volle DH, Duggavathi R, Magnier BC, Houten SM, Cummins CL, Lobaccaro JM, Verhoeven G, Schoonjans K, Auwerx J. The small heterodimer partner is a gonadal gatekeeper of sexual maturation in male mice. Genes & Development. 21: 303-15. PMID 17289919 DOI: 10.1101/Gad.409307 |
0.378 |
|
| 2006 |
Cummins CL, Mangelsdorf DJ. Liver X receptors and cholesterol homoeostasis: Spotlight on the adrenal gland Biochemical Society Transactions. 34: 1110-1113. PMID 17073762 DOI: 10.1042/Bst0341110 |
0.375 |
|
| 2006 |
Cummins CL, Volle DH, Zhang Y, McDonald JG, Sion B, Lefrançois-Martinez AM, Caira F, Veyssière G, Mangelsdorf DJ, Lobaccaro JM. Liver X receptors regulate adrenal cholesterol balance. The Journal of Clinical Investigation. 116: 1902-12. PMID 16823488 DOI: 10.1172/Jci28400 |
0.356 |
|
| 2006 |
Rottiers V, Motola DL, Gerisch B, Cummins CL, Nishiwaki K, Mangelsdorf DJ, Antebi A. Hormonal control of C. elegans dauer formation and life span by a Rieske-like oxygenase. Developmental Cell. 10: 473-82. PMID 16563875 DOI: 10.1016/J.Devcel.2006.02.008 |
0.328 |
|
| 2006 |
Motola DL, Cummins CL, Rottiers V, Sharma KK, Li T, Li Y, Suino-Powell K, Xu HE, Auchus RJ, Antebi A, Mangelsdorf DJ. Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans. Cell. 124: 1209-23. PMID 16529801 DOI: 10.1016/J.Cell.2006.01.037 |
0.353 |
|
| 2005 |
Inagaki T, Choi M, Moschetta A, Peng L, Cummins CL, McDonald JG, Luo G, Jones SA, Goodwin B, Richardson JA, Gerard RD, Repa JJ, Mangelsdorf DJ, Kliewer SA. Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis. Cell Metabolism. 2: 217-25. PMID 16213224 DOI: 10.1016/J.Cmet.2005.09.001 |
0.381 |
|
| 2004 |
Benet LZ, Cummins CL, Wu CY. Unmasking the dynamic interplay between efflux transporters and metabolic enzymes. International Journal of Pharmaceutics. 277: 3-9. PMID 15158963 DOI: 10.1016/J.Ijpharm.2002.12.002 |
0.552 |
|
| 2004 |
Volle DH, Repa JJ, Mazur A, Cummins CL, Val P, Henry-Berger J, Caira F, Veyssiere G, Mangelsdorf DJ, Lobaccaro JM. Regulation of the aldo-keto reductase gene akr1b7 by the nuclear oxysterol receptor LXRalpha (liver X receptor-alpha) in the mouse intestine: putative role of LXRs in lipid detoxification processes. Molecular Endocrinology (Baltimore, Md.). 18: 888-98. PMID 14739254 DOI: 10.1210/Me.2003-0338 |
0.399 |
|
| 2004 |
Cummins CL, Jacobsen W, Christians U, Benet LZ. CYP3A4-transfected Caco-2 cells as a tool for understanding biochemical absorption barriers: studies with sirolimus and midazolam. The Journal of Pharmacology and Experimental Therapeutics. 308: 143-55. PMID 14569063 DOI: 10.1124/Jpet.103.058065 |
0.558 |
|
| 2003 |
Benet LZ, Cummins CL, Wu CY. Transporter-enzyme interactions: implications for predicting drug-drug interactions from in vitro data. Current Drug Metabolism. 4: 393-8. PMID 14529371 DOI: 10.2174/1389200033489389 |
0.549 |
|
| 2003 |
Cummins CL, Salphati L, Reid MJ, Benet LZ. In vivo modulation of intestinal CYP3A metabolism by P-glycoprotein: studies using the rat single-pass intestinal perfusion model. The Journal of Pharmacology and Experimental Therapeutics. 305: 306-14. PMID 12649383 DOI: 10.1124/Jpet.102.044719 |
0.536 |
|
| 2002 |
Unger M, Holzgrabe U, Jacobsen W, Cummins C, Benet LZ. Inhibition of cytochrome P450 3A4 by extracts and kavalactones of Piper methysticum (Kava-Kava). Planta Medica. 68: 1055-8. PMID 12494328 DOI: 10.1055/S-2002-36360 |
0.463 |
|
| 2002 |
Cummins CL, Wu CY, Benet LZ. Sex-related differences in the clearance of cytochrome P450 3A4 substrates may be caused by P-glycoprotein. Clinical Pharmacology and Therapeutics. 72: 474-89. PMID 12426511 DOI: 10.1067/Mcp.2002.128388 |
0.469 |
|
| 2002 |
Cummins CL, Jacobsen W, Benet LZ. Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4. The Journal of Pharmacology and Experimental Therapeutics. 300: 1036-45. PMID 11861813 DOI: 10.1124/Jpet.300.3.1036 |
0.547 |
|
| 2002 |
Flanagan SD, Cummins CL, Susanto M, Liu X, Takahashi LH, Benet LZ. Comparison of furosemide and vinblastine secretion from cell lines overexpressing multidrug resistance protein (P-glycoprotein) and multidrug resistance-associated proteins (MRP1 and MRP2). Pharmacology. 64: 126-34. PMID 11834888 DOI: 10.1159/000056161 |
0.497 |
|
| 2001 |
Cummins CL, Mangravite LM, Benet LZ. Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate. Pharmaceutical Research. 18: 1102-9. PMID 11587480 DOI: 10.1023/A:1010914624111 |
0.536 |
|
| 2001 |
Benet LZ, Cummins CL. The drug efflux-metabolism alliance: biochemical aspects. Advanced Drug Delivery Reviews. 50: S3-11. PMID 11576692 DOI: 10.1016/S0169-409X(01)00178-8 |
0.545 |
|
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