| Year |
Citation |
Score |
| 2024 |
Swarnkar G, Semenkovich NP, Arra M, Mims DK, Naqvi SK, Peterson T, Mbalaviele G, Wu CL, Abu-Amer Y. DNA hypomethylation ameliorates erosive inflammatory arthritis by modulating interferon regulatory factor-8. Proceedings of the National Academy of Sciences of the United States of America. 121: e2310264121. PMID 38319963 DOI: 10.1073/pnas.2310264121 |
0.351 |
|
| 2023 |
Liu M, Jayaraman K, Mehla J, Diwan D, Nelson JW, Hussein AE, Vellimana AK, Abu-Amer Y, Zipfel GJ, Athiraman U. Isoflurane Conditioning Provides Protection against Subarachnoid Hemorrhage Induced Delayed Cerebral Ischemia through NF-kB Inhibition. Biomedicines. 11. PMID 37189781 DOI: 10.3390/biomedicines11041163 |
0.373 |
|
| 2023 |
MacLauchlan S, Kushwaha P, Tai A, Chen J, Manning C, Swarnkar G, Abu-Amer Y, Fitzgerald KA, Sharma S, Gravallese EM. STING-dependent interferon signatures restrict osteoclast differentiation and bone loss in mice. Proceedings of the National Academy of Sciences of the United States of America. 120: e2210409120. PMID 37023130 DOI: 10.1073/pnas.2210409120 |
0.448 |
|
| 2022 |
Sun K, Wang C, Xiao J, Brodt MD, Yuan L, Yang T, Alippe Y, Hu H, Hao D, Abu-Amer Y, Silva MJ, Shen J, Mbalaviele G. Fracture healing is delayed in the absence of gasdermin - interleukin-1 signaling. Elife. 11. PMID 35244027 DOI: 10.7554/eLife.75753 |
0.318 |
|
| 2022 |
Arra M, Swarnkar G, Alippe Y, Mbalaviele G, Abu-Amer Y. IκB-ζ signaling promotes chondrocyte inflammatory phenotype, senescence, and erosive joint pathology. Bone Research. 10: 12. PMID 35145063 DOI: 10.1038/s41413-021-00183-9 |
0.41 |
|
| 2021 |
Alippe Y, Kress D, Ricci B, Sun K, Yang T, Wang C, Xiao J, Abu-Amer Y, Mbalaviele G. Actions of the NLRP3 and NLRC4 inflammasomes overlap in bone resorption. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21837. PMID 34383985 DOI: 10.1096/fj.202100767RR |
0.37 |
|
| 2021 |
Swarnkar G, Arra M, Adapala S, Abu-Amer Y. Methods to Analyze the Roles of TAK1, TRAF6, and NEMO in the Regulation of NF-κB Signaling by RANK Stimulation During Osteoclastogenesis. Methods in Molecular Biology (Clifton, N.J.). 2366: 267-282. PMID 34236644 DOI: 10.1007/978-1-0716-1669-7_16 |
0.512 |
|
| 2021 |
Swarnkar G, Arra M, Adapala S, Abu-Amer Y. Methods to Analyze the Roles of TAK1, TRAF6, and NEMO in the Regulation of NF-κB Signaling by RANK Stimulation During Osteoclastogenesis. Methods in Molecular Biology (Clifton, N.J.). 2366: 267-282. PMID 34236644 DOI: 10.1007/978-1-0716-1669-7_16 |
0.512 |
|
| 2021 |
Golman M, Li X, Skouteris D, Abraham AA, Song L, Abu-Amer Y, Thomopoulos S. Enhanced Tendon-to-Bone Healing via IKKβ Inhibition in a Rat Rotator Cuff Model. The American Journal of Sports Medicine. 363546520985203. PMID 33507808 DOI: 10.1177/0363546520985203 |
0.383 |
|
| 2020 |
Xiao J, Wang C, Yao JC, Alippe Y, Yang T, Kress D, Sun K, Kostecki KL, Monahan JB, Veis DJ, Abu-Amer Y, Link DC, Mbalaviele G. Radiation causes tissue damage by dysregulating inflammasome-gasdermin D signaling in both host and transplanted cells. Plos Biology. 18: e3000807. PMID 32760056 DOI: 10.1371/Journal.Pbio.3000807 |
0.321 |
|
| 2020 |
Arra M, Swarnkar G, Ke K, Otero JE, Ying J, Duan X, Maruyama T, Rai MF, O'Keefe RJ, Mbalaviele G, Shen J, Abu-Amer Y. LDHA-mediated ROS generation in chondrocytes is a potential therapeutic target for osteoarthritis. Nature Communications. 11: 3427. PMID 32647171 DOI: 10.1038/S41467-020-17242-0 |
0.663 |
|
| 2020 |
Adapala NS, Swarnkar G, Arra M, Shen J, Mbalaviele G, Ke K, Abu-Amer Y. Inflammatory osteolysis is regulated by site-specific ISGylation of the scaffold protein NEMO. Elife. 9. PMID 32202502 DOI: 10.7554/Elife.56095 |
0.506 |
|
| 2020 |
Ying J, Xu T, Wang C, Jin H, Tong P, Guan J, Abu-Amer Y, O'Keefe R, Shen J. Dnmt3b ablation impairs fracture repair through upregulation of Notch pathway. Jci Insight. 5. PMID 32051335 DOI: 10.1172/Jci.Insight.131816 |
0.341 |
|
| 2020 |
Adapala NS, Swarnkar G, Arra M, Shen J, Mbalaviele G, Ke K, Abu-Amer Y. Author response: Inflammatory osteolysis is regulated by site-specific ISGylation of the scaffold protein NEMO Elife. DOI: 10.7554/Elife.56095.Sa2 |
0.355 |
|
| 2019 |
Ke K, Arra M, Abu-Amer Y. Mechanisms Underlying Bone Loss Associated with Gut Inflammation. International Journal of Molecular Sciences. 20. PMID 31847438 DOI: 10.3390/Ijms20246323 |
0.466 |
|
| 2019 |
Wang C, Xiao J, Nowak K, Gunasekera K, Alippe Y, Speckman S, Yang T, Kress D, Abu-Amer Y, Hottiger MO, Mbalaviele G. PARP1 hinders histone H2B occupancy at the NFATc1 promoter to restrain osteoclast differentiation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 31793068 DOI: 10.1002/jbmr.3927 |
0.366 |
|
| 2019 |
Chen TH, Arra M, Mbalaviele G, Swarnkar G, Abu-Amer Y. Inflammatory Responses Reprogram T Through Impairment of Neuropilin-1. Scientific Reports. 9: 10429. PMID 31320680 DOI: 10.1038/S41598-019-46934-X |
0.364 |
|
| 2019 |
Ke K, Chen TH, Arra M, Mbalaviele G, Swarnkar G, Abu-Amer Y. Attenuation of NF-κB in intestinal epithelial cells is sufficient to mitigate the bone loss co-morbidity of experimental mouse colitis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 31107556 DOI: 10.1002/Jbmr.3759 |
0.559 |
|
| 2019 |
Abu-Amer W, Arra M, Clohisy JCF, Abu-Amer Y, Swarnkar G. Targeting vascular endothelial growth factor ameliorates PMMA-particles induced inflammatory osteolysis in murine calvaria. Bone. 123: 86-91. PMID 30904629 DOI: 10.1016/J.Bone.2019.03.025 |
0.382 |
|
| 2019 |
Abraham AC, Shah SA, Golman M, Song L, Li X, Kurtaliaj I, Akbar M, Millar NL, Abu-Amer Y, Galatz LM, Thomopoulos S. Targeting the NF-κB signaling pathway in chronic tendon disease. Science Translational Medicine. 11. PMID 30814338 DOI: 10.1126/Scitranslmed.Aav4319 |
0.499 |
|
| 2019 |
Abu-Amer Y. NF-kB mediates inflammation-induced metabolic and senescence changes in OA Osteoarthritis and Cartilage. 27: S20-S21. DOI: 10.1016/J.JOCA.2019.02.028 |
0.321 |
|
| 2018 |
Xiao J, Wang C, Yao JC, Alippe Y, Xu C, Kress D, Civitelli R, Abu-Amer Y, Kanneganti TD, Link DC, Mbalaviele G. Gasdermin D mediates the pathogenesis of neonatal-onset multisystem inflammatory disease in mice. Plos Biology. 16: e3000047. PMID 30388107 DOI: 10.1371/Journal.Pbio.3000047 |
0.364 |
|
| 2018 |
Rohatgi N, Zou W, Collins PL, Brestoff JR, Chen TH, Abu-Amer Y, Teitelbaum SL. ASXL1 impairs osteoclast formation by epigenetic regulation of NFATc1. Blood Advances. 2: 2467-2477. PMID 30266822 DOI: 10.1182/Bloodadvances.2018018309 |
0.483 |
|
| 2018 |
Wang C, Hockerman S, Jacobsen EJ, Alippe Y, Selness SR, Hope HR, Hirsch JL, Mnich SJ, Saabye MJ, Hood WF, Bonar SL, Abu-Amer Y, Haimovich A, Hoffman HM, Monahan JB, et al. Selective inhibition of the p38α MAPK-MK2 axis inhibits inflammatory cues including inflammasome priming signals. The Journal of Experimental Medicine. PMID 29549113 DOI: 10.1084/Jem.20172063 |
0.419 |
|
| 2017 |
Chen M, Zhou H, Xu Y, Qiu L, Hu Z, Qin X, Chen S, Zhang Y, Cao Q, Abu-Amer Y, Ying Z. Lung-Specific Overexpression of Constitutively Active IKK2 Induces Pulmonary and Systemic Inflammations but Not Hypothalamic Inflammation and Glucose Intolerance. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 29036520 DOI: 10.1093/Toxsci/Kfx154 |
0.352 |
|
| 2017 |
Wang C, Abu-Amer Y, J O'Keefe R, Shen J. Loss of Dnmt3b in Chondrocytes Leads to Delayed Endochondral Ossification and Fracture Repair. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 29024060 DOI: 10.1002/Jbmr.3305 |
0.341 |
|
| 2017 |
Swarnkar G, Chen TH, Arra M, Nasir AM, Mbalaviele G, Abu-Amer Y. NUMBL Interacts with TAK1, TRAF6 and NEMO to Negatively Regulate NF-κB Signaling During Osteoclastogenesis. Scientific Reports. 7: 12600. PMID 28974699 DOI: 10.1038/S41598-017-12707-7 |
0.538 |
|
| 2017 |
Alippe Y, Wang C, Ricci B, Xiao J, Qu C, Zou W, Novack DV, Abu-Amer Y, Civitelli R, Mbalaviele G. Bone matrix components activate the NLRP3 inflammasome and promote osteoclast differentiation. Scientific Reports. 7: 6630. PMID 28747793 DOI: 10.1038/S41598-017-07014-0 |
0.46 |
|
| 2017 |
Wang C, Xu CX, Alippe Y, Qu C, Xiao J, Schipani E, Civitelli R, Abu-Amer Y, Mbalaviele G. Chronic inflammation triggered by the NLRP3 inflammasome in myeloid cells promotes growth plate dysplasia by mesenchymal cells. Scientific Reports. 7: 4880. PMID 28687790 DOI: 10.1038/S41598-017-05033-5 |
0.479 |
|
| 2016 |
Zou W, Rohatgi N, Chen TH, Schilling J, Abu-Amer Y, Teitelbaum SL. PPAR-γ regulates pharmacological but not physiological or pathological osteoclast formation. Nature Medicine. 22: 1203-1205. PMID 27824823 DOI: 10.1038/Nm.4208 |
0.38 |
|
| 2016 |
Swarnkar G, Shim K, Nasir AM, Seehra K, Chen HP, Mbalaviele G, Abu-Amer Y. Myeloid Deletion of Nemo Causes Osteopetrosis in Mice Owing to Upregulation of Transcriptional Repressors. Scientific Reports. 6: 29896. PMID 27435916 DOI: 10.1038/Srep29896 |
0.502 |
|
| 2016 |
Shen J, Abu-Amer Y, O'Keefe RJ, McAlinden A. Inflammation and epigenetic regulation in osteoarthritis. Connective Tissue Research. PMID 27389927 DOI: 10.1080/03008207.2016.1208655 |
0.433 |
|
| 2016 |
Wang C, Qu C, Alippe Y, Bonar SL, Civitelli R, Abu-Amer Y, Hottiger MO, Mbalaviele G. Poly-ADP-ribosylation-mediated degradation of ARTD1 by the NLRP3 inflammasome is a prerequisite for osteoclast maturation. Cell Death & Disease. 7: e2153. PMID 27010854 DOI: 10.1038/Cddis.2016.58 |
0.561 |
|
| 2015 |
Chen TH, Swarnkar G, Mbalaviele G, Abu-Amer Y. Myeloid lineage skewing due to exacerbated NF-κB signaling facilitates osteopenia in Scurfy mice. Cell Death & Disease. 6: e1723. PMID 25880090 DOI: 10.1038/Cddis.2015.87 |
0.575 |
|
| 2015 |
Swarnkar G, Abu-Amer Y. Regulation of NF-κB signaling in osteoclasts and myeloid progenitors. Methods in Molecular Biology (Clifton, N.J.). 1280: 527-42. PMID 25736770 DOI: 10.1007/978-1-4939-2422-6_31 |
0.574 |
|
| 2015 |
Swarnkar G, Karuppaiah K, Mbalaviele G, Chen TH, Abu-Amer Y. Osteopetrosis in TAK1-deficient mice owing to defective NF-κB and NOTCH signaling. Proceedings of the National Academy of Sciences of the United States of America. 112: 154-9. PMID 25535389 DOI: 10.1073/Pnas.1415213112 |
0.534 |
|
| 2015 |
Qu C, Bonar SL, Hickman-Brecks CL, Abu-Amer S, McGeough MD, Peña CA, Broderick L, Yang C, Grimston SK, Kading J, Abu-Amer Y, Novack DV, Hoffman HM, Civitelli R, Mbalaviele G. NLRP3 mediates osteolysis through inflammation-dependent and -independent mechanisms. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1269-79. PMID 25477279 DOI: 10.1096/Fj.14-264804 |
0.499 |
|
| 2014 |
Swarnkar G, Zhang K, Mbalaviele G, Long F, Abu-Amer Y. Constitutive activation of IKK2/NF-κB impairs osteogenesis and skeletal development. Plos One. 9: e91421. PMID 24618907 DOI: 10.1371/Journal.Pone.0091421 |
0.442 |
|
| 2014 |
Cassel SL, Janczy JR, Bing X, Wilson SP, Olivier AK, Otero JE, Iwakura Y, Shayakhmetov DM, Bassuk AG, Abu-Amer Y, Brogden KA, Burns TL, Sutterwala FS, Ferguson PJ. Inflammasome-independent IL-1β mediates autoinflammatory disease in Pstpip2-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 111: 1072-7. PMID 24395802 DOI: 10.1073/Pnas.1318685111 |
0.627 |
|
| 2013 |
Zhang Y, Otero JE, Abu-Amer Y. Ubiquitin-like domain of IKKβ regulates osteoclastogenesis and osteolysis. Calcified Tissue International. 93: 78-85. PMID 23686246 DOI: 10.1007/S00223-013-9735-5 |
0.717 |
|
| 2013 |
Abu-Amer Y. NF-κB signaling and bone resorption Osteoporosis International. 24: 2377-2386. PMID 23468073 DOI: 10.1007/S00198-013-2313-X |
0.604 |
|
| 2013 |
Yamanaka Y, Clohisy JC, Ito H, Matsuno T, Abu-Amer Y. Blockade of JNK and NFAT pathways attenuates orthopedic particle-stimulated osteoclastogenesis of human osteoclast precursors and murine calvarial osteolysis. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 31: 67-72. PMID 22847537 DOI: 10.1002/Jor.22200 |
0.5 |
|
| 2012 |
Otero JE, Chen T, Zhang K, Abu-Amer Y. Constitutively active canonical NF-κB pathway induces severe bone loss in mice. Plos One. 7: e38694. PMID 22685599 DOI: 10.1371/Journal.Pone.0038694 |
0.728 |
|
| 2012 |
Alhawagri M, Yamanaka Y, Ballard D, Oltz E, Abu-Amer Y. Lysine392, a K63-linked ubiquitination site in NEMO, mediates inflammatory osteoclastogenesis and osteolysis. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 30: 554-60. PMID 21913221 DOI: 10.1002/Jor.21555 |
0.569 |
|
| 2011 |
Yamanaka Y, Karuppaiah K, Abu-Amer Y. Polyubiquitination events mediate polymethylmethacrylate (PMMA) particle activation of NF-kappaB pathway. The Journal of Biological Chemistry. 286: 23735-41. PMID 21566132 DOI: 10.1074/Jbc.M111.223669 |
0.511 |
|
| 2011 |
Dai S, Abu-Amer W, Karuppaiah K, Abu-Amer Y. Evidence that the kinase-truncated c-Src regulates NF-κB signaling by targeting NEMO Journal of Cellular Biochemistry. 112: 2463-2470. PMID 21538482 DOI: 10.1002/Jcb.23170 |
0.519 |
|
| 2010 |
Darwech I, Otero JE, Alhawagri MA, Abu-Amer Y. Tyrosine phosphorylation is required for IkappaB kinase-beta (IKKbeta) activation and function in osteoclastogenesis. The Journal of Biological Chemistry. 285: 25522-30. PMID 20534585 DOI: 10.1074/Jbc.M110.121533 |
0.687 |
|
| 2010 |
Zhang Z, Xing X, Hensley G, Chang LW, Liao W, Abu-Amer Y, Sandell LJ. Resistin induces expression of proinflammatory cytokines and chemokines in human articular chondrocytes via transcription and messenger RNA stabilization. Arthritis and Rheumatism. 62: 1993-2003. PMID 20506172 DOI: 10.1002/Art.27473 |
0.349 |
|
| 2010 |
Otero JE, Dai S, Alhawagri MA, Darwech I, Abu-Amer Y. IKKbeta activation is sufficient for RANK-independent osteoclast differentiation and osteolysis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 1282-94. PMID 20200955 DOI: 10.1002/Jbmr.4 |
0.732 |
|
| 2009 |
Darwech I, Otero J, Alhawagri M, Dai S, Abu-Amer Y. Impediment of NEMO oligomerization inhibits osteoclastogenesis and osteolysis. Journal of Cellular Biochemistry. 108: 1337-45. PMID 19830703 DOI: 10.1002/Jcb.22364 |
0.722 |
|
| 2009 |
Abu-Amer Y. Inflammation, cancer, and bone loss. Current Opinion in Pharmacology. 9: 427-33. PMID 19577517 DOI: 10.1016/J.Coph.2009.06.007 |
0.453 |
|
| 2008 |
Yamanaka Y, Abu-Amer W, Foglia D, Otero J, Clohisy JC, Abu-Amer Y. NFAT2 is an essential mediator of orthopedic particle-induced osteoclastogenesis. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 26: 1577-84. PMID 18655139 DOI: 10.1002/Jor.20714 |
0.683 |
|
| 2008 |
Otero JE, Dai S, Foglia D, Alhawagri M, Vacher J, Pasparakis M, Abu-Amer Y. Defective osteoclastogenesis by IKKbeta-null precursors is a result of receptor activator of NF-kappaB ligand (RANKL)-induced JNK-dependent apoptosis and impaired differentiation. The Journal of Biological Chemistry. 283: 24546-53. PMID 18567579 DOI: 10.1074/Jbc.M800434200 |
0.717 |
|
| 2008 |
Abu-Amer Y, Darwech I, Otero J. Role of the NF-kappaB axis in immune modulation of osteoclasts and bone loss. Autoimmunity. 41: 204-11. PMID 18365833 DOI: 10.1080/08916930701694543 |
0.702 |
|
| 2007 |
Dufort FJ, Bleiman BF, Gumina MR, Blair D, Wagner DJ, Roberts MF, Abu-Amer Y, Chiles TC. Cutting edge: IL-4-mediated protection of primary B lymphocytes from apoptosis via Stat6-dependent regulation of glycolytic metabolism. Journal of Immunology (Baltimore, Md. : 1950). 179: 4953-7. PMID 17911579 DOI: 10.4049/Jimmunol.179.8.4953 |
0.34 |
|
| 2007 |
Abu-Amer Y, Darwech I, Clohisy JC. Aseptic loosening of total joint replacements: mechanisms underlying osteolysis and potential therapies. Arthritis Research & Therapy. 9: S6. PMID 17634145 DOI: 10.1186/Ar2170 |
0.457 |
|
| 2007 |
Kiesel J, Miller C, Abu-Amer Y, Aurora R. Systems level analysis of osteoclastogenesis reveals intrinsic and extrinsic regulatory interactions. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 236: 2181-97. PMID 17584858 DOI: 10.1002/Dvdy.21206 |
0.499 |
|
| 2006 |
Yamanaka Y, Abu-Amer Y, Faccio R, Clohisy JC. Map kinase c-JUN N-terminal kinase mediates PMMA induction of osteoclasts. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 24: 1349-57. PMID 16732613 DOI: 10.1002/Jor.20199 |
0.524 |
|
| 2006 |
Clohisy JC, Yamanaka Y, Faccio R, Abu-Amer Y. Inhibition of IKK activation, through sequestering NEMO, blocks PMMA-induced osteoclastogenesis and calvarial inflammatory osteolysis. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 24: 1358-65. PMID 16705717 DOI: 10.1002/Jor.20184 |
0.589 |
|
| 2006 |
Mbalaviele G, Anderson G, Jones A, De Ciechi P, Settle S, Mnich S, Thiede M, Abu-Amer Y, Portanova J, Monahan J. Inhibition of p38 mitogen-activated protein kinase prevents inflammatory bone destruction. The Journal of Pharmacology and Experimental Therapeutics. 317: 1044-53. PMID 16501068 DOI: 10.1124/Jpet.105.100362 |
0.53 |
|
| 2006 |
Abu-Amer Y, Faccio R. Therapeutic approaches in bone pathogeneses: targeting the IKK/NF-κB axis Future Rheumatology. 1: 133-146. DOI: 10.2217/17460816.1.1.133 |
0.585 |
|
| 2005 |
Abu-Amer Y. Advances in osteoclast differentiation and function. Current Drug Targets. Immune, Endocrine and Metabolic Disorders. 5: 347-55. PMID 16178795 DOI: 10.2174/1568008054863808 |
0.489 |
|
| 2005 |
Hirayama T, Dai S, Abbas S, Yamanaka Y, Abu-Amer Y. Inhibition of inflammatory bone erosion by constitutively active STAT-6 through blockade of JNK and NF-kappaB activation. Arthritis and Rheumatism. 52: 2719-29. PMID 16142755 DOI: 10.1002/Art.21286 |
0.616 |
|
| 2005 |
Silva MJ, Brodt MD, Ko M, Abu-Amer Y. Impaired marrow osteogenesis is associated with reduced endocortical bone formation but does not impair periosteal bone formation in long bones of SAMP6 mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 419-27. PMID 15746986 DOI: 10.1359/Jbmr.041128 |
0.41 |
|
| 2004 |
Kitaura H, Sands MS, Aya K, Zhou P, Hirayama T, Uthgenannt B, Wei S, Takeshita S, Novack DV, Silva MJ, Abu-Amer Y, Ross FP, Teitelbaum SL. Marrow stromal cells and osteoclast precursors differentially contribute to TNF-alpha-induced osteoclastogenesis in vivo. Journal of Immunology (Baltimore, Md. : 1950). 173: 4838-46. PMID 15470024 DOI: 10.4049/Jimmunol.173.8.4838 |
0.437 |
|
| 2004 |
Abu-Amer Y, Abbas S, Hirayama T. TNF receptor type 1 regulates RANK ligand expression by stromal cells and modulates osteoclastogenesis. Journal of Cellular Biochemistry. 93: 980-9. PMID 15389885 DOI: 10.1002/Jcb.20197 |
0.412 |
|
| 2004 |
Dai S, Hirayama T, Abbas S, Abu-Amer Y. The IkappaB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks osteoclastogenesis and bone erosion in inflammatory arthritis. The Journal of Biological Chemistry. 279: 37219-22. PMID 15252035 DOI: 10.1074/Jbc.C400258200 |
0.587 |
|
| 2004 |
Clohisy JC, Hirayama T, Frazier E, Han SK, Abu-Amer Y. NF-kB signaling blockade abolishes implant particle-induced osteoclastogenesis. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 22: 13-20. PMID 14656654 DOI: 10.1016/S0736-0266(03)00156-6 |
0.534 |
|
| 2003 |
Clohisy JC, Roy BC, Biondo C, Frazier E, Willis D, Teitelbaum SL, Abu-Amer Y. Direct inhibition of NF-kappa B blocks bone erosion associated with inflammatory arthritis. Journal of Immunology (Baltimore, Md. : 1950). 171: 5547-53. PMID 14607962 DOI: 10.4049/Jimmunol.171.10.5547 |
0.58 |
|
| 2003 |
Abbas S, Clohisy JC, Abu-Amer Y. Mitogen-activated protein (MAP) kinases mediate PMMA-induction of osteoclasts Journal of Orthopaedic Research. 21: 1041-1048. PMID 14554217 DOI: 10.1016/S0736-0266(03)00081-0 |
0.524 |
|
| 2003 |
Abbas S, Zhang YH, Clohisy JC, Abu-Amer Y. Tumor necrosis factor-alpha inhibits pre-osteoblast differentiation through its type-1 receptor. Cytokine. 22: 33-41. PMID 12946103 DOI: 10.1016/S1043-4666(03)00106-6 |
0.55 |
|
| 2003 |
Khan E, Abu-Amer Y. Activation of peroxisome proliferator-activated receptor-gamma inhibits differentiation of preosteoblasts. The Journal of Laboratory and Clinical Medicine. 142: 29-34. PMID 12878983 DOI: 10.1016/S0022-2143(03)00058-1 |
0.483 |
|
| 2003 |
Gupta A, Lee BS, Khadeer MA, Tang Z, Chellaiah M, Abu-Amer Y, Goldknopf J, Hruska KA. Leupaxin is a critical adaptor protein in the adhesion zone of the osteoclast. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 18: 669-85. PMID 12674328 DOI: 10.1359/Jbmr.2003.18.4.669 |
0.415 |
|
| 2003 |
Abbas S, Abu-Amer Y. Dominant-negative IkappaB facilitates apoptosis of osteoclasts by tumor necrosis factor-alpha. The Journal of Biological Chemistry. 278: 20077-82. PMID 12637573 DOI: 10.1074/Jbc.M208619200 |
0.543 |
|
| 2003 |
Clohisy JC, Frazier E, Hirayama T, Abu-Amer Y. RANKL is an essential cytokine mediator of polymethylmethacrylate particle-induced osteoclastogenesis. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 21: 202-12. PMID 12568950 DOI: 10.1016/S0736-0266(02)00133-X |
0.52 |
|
| 2002 |
Lam J, Abu-Amer Y, Nelson CA, Fremont DH, Ross FP, Teitelbaum SL. Tumour necrosis factor superfamily cytokines and the pathogenesis of inflammatory osteolysis. Annals of the Rheumatic Diseases. 61: ii82-3. PMID 12379631 DOI: 10.1136/Ard.61.Suppl_2.Ii82 |
0.471 |
|
| 2002 |
Clohisy JC, Teitelbaum S, Chen S, Erdmann JM, Abu-Amer Y. Tumor necrosis factor-alpha mediates polymethylmethacrylate particle-induced NF-kappaB activation in osteoclast precursor cells. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 20: 174-81. PMID 11918294 DOI: 10.1016/S0736-0266(01)00088-2 |
0.537 |
|
| 2001 |
Abu-Amer Y, Dowdy SF, Ross FP, Clohisy JC, Teitelbaum SL. TAT Fusion Proteins Containing Tyrosine 42-deleted IκBα Arrest Osteoclastogenesis Journal of Biological Chemistry. 276: 30499-30503. PMID 11408488 DOI: 10.1074/jbc.M104725200 |
0.42 |
|
| 2001 |
Abu-Amer Y. IL-4 abrogates osteoclastogenesis through STAT6-dependent inhibition of NF-κB Journal of Clinical Investigation. 107: 1375-1385. PMID 11390419 DOI: 10.1172/Jci10530 |
0.486 |
|
| 2001 |
Zhang YH, Heulsmann A, Tondravi MM, Mukherjee A, Abu-Amer Y. Tumor necrosis factor-α (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathways Journal of Biological Chemistry. 276: 563-568. PMID 11032840 DOI: 10.1074/Jbc.M008198200 |
0.554 |
|
| 2000 |
Abu-Amer Y, Erdmann J, Alexopoulou L, Kollias G, Patrick Ross F, Teitelbaum SL. Tumor necrosis factor receptors types 1 and 2 differentially regulate osteoclastogenesis Journal of Biological Chemistry. 275: 27307-27310. PMID 10874036 DOI: 10.1074/Jbc.M003886200 |
0.492 |
|
| 2000 |
Mbalaviele G, Abu-Amer Y, Meng A, Jaiswal R, Beck S, Pittenger MF, Thiede MA, Marshak DR. Activation of peroxisome proliferator-activated receptor-gamma pathway inhibits osteoclast differentiation. The Journal of Biological Chemistry. 275: 14388-93. PMID 10799521 DOI: 10.1074/Jbc.275.19.14388 |
0.429 |
|
| 2000 |
Inoue M, Ross FP, Erdmann JM, Abu-Amer Y, Wei S, Teitelbaum SL. Tumor necrosis factor α regulates αvβ5 integrin expression by osteoclast precursors in vitro and in vivo Endocrinology. 141: 284-290. PMID 10614649 DOI: 10.1210/Endo.141.1.7285 |
0.452 |
|
| 1999 |
Adams AE, Abu-Amer Y, Chappel J, Stueckle S, Ross FP, Teitelbaum SL, Suva LJ. 1,25 dihydroxyvitamin D3 and dexamethasone induce the cyclooxygenase 1 gene in osteoclast-supporting stromal cells. Journal of Cellular Biochemistry. 74: 587-95. PMID 10440928 DOI: 10.1002/(Sici)1097-4644(19990915)74:4<587::Aid-Jcb8>3.0.Co;2-G |
0.372 |
|
| 1999 |
Merkel KD, Erdmann JM, McHugh KP, Abu-Amer Y, Ross FP, Teitelbaum SL. Tumor necrosis factor-α mediates orthopedic implant osteolysis American Journal of Pathology. 154: 203-210. PMID 9916934 DOI: 10.1016/S0002-9440(10)65266-2 |
0.462 |
|
| 1998 |
Abu-Amer Y, Rossl FP, McHugh KP, Livolsi A, Peyron JF, Teitelbaum SL. Tumor necrosis factor-α activation of nuclear transcription factor-κB in marrow macrophages is mediated by c-Src tyrosine phosphorylation of IκBα Journal of Biological Chemistry. 273: 29417-29423. PMID 9792645 DOI: 10.1074/Jbc.273.45.29417 |
0.543 |
|
| 1997 |
Chappel J, Ross FP, Abu-Amer Y, Shaw A, Teitelbaum SL. 1,25-dihydroxyvitamin D3 regulates pp60(c-src) activity and expression of a pp60(c-src) activating phosphatase Journal of Cellular Biochemistry. 67: 432-438. PMID 9383703 DOI: 10.1002/(Sici)1097-4644(19971215)67:4<432::Aid-Jcb2>3.0.Co;2-T |
0.306 |
|
| 1997 |
Abu-Amer Y, Tondravi MM. NF-κB and bone: The breaking point Nature Medicine. 3: 1189-1190. PMID 9359684 DOI: 10.1038/Nm1197-1189 |
0.531 |
|
| 1997 |
Abu-Amer Y, Ross FP, Edwards J, Teitelbaum SL. Lipopolysaccharide-stimulated osteoclastogenesis is mediated by tumor necrosis factor via its P55 receptor Journal of Clinical Investigation. 100: 1557-1565. PMID 9294124 DOI: 10.1172/Jci119679 |
0.481 |
|
| 1997 |
Abu-Amer Y, Ross FP, Schlesinger P, Tondravi MM, Teitelbaum SL. Substrate recognition by osteoclast precursors induces C- src/microtubule association Journal of Cell Biology. 137: 247-254. PMID 9105052 DOI: 10.1083/Jcb.137.1.247 |
0.357 |
|
| 1996 |
Matayoshi A, Brown C, Dipersio JF, Haug J, Abu-Amer Y, Liapis H, Kuestner R, Pacifici R. Human blood-mobilized hematopoietic precursors differentiate into osteoclasts in the absence of stromal cells Proceedings of the National Academy of Sciences of the United States of America. 93: 10785-10790. PMID 8855258 DOI: 10.1073/Pnas.93.20.10785 |
0.403 |
|
| 1995 |
Teitelbaum SL, Abu-Amer Y, Ross FP. Molecular mechanisms of bone resorption Journal of Cellular Biochemistry. 59: 1-10. PMID 8530528 DOI: 10.1002/Jcb.240590102 |
0.403 |
|
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