Eduardo M. Sotomayor - Publications

Affiliations: 
Biology (Cell Biology, Microbiology, Molecular Biology) University of South Florida, Tampa, FL, United States 
Area:
Cell Biology, Immunology, Molecular Biology

270 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Vidal-Vanaclocha F, Crende O, García de Durango C, Herreros-Pomares A, López-Doménech S, González Á, Ruiz-Casares E, Vilboux T, Caruso R, Duran H, Gil A, Ielpo B, Lapuente F, Quijano Y, Vicente E, ... ... Sotomayor EM, et al. Liver Prometastatic Reaction: Stimulating Factors and Responsive Cancer Phenotypes. Seminars in Cancer Biology. PMID 32805395 DOI: 10.1016/J.Semcancer.2020.08.001  0.314
2020 Banik D, Noonepalle S, Hadley M, Palmer E, Gracia-Hernandez M, Zevallos-Delgado C, Manhas N, Simonyan H, Young CN, Popratiloff A, Chiappinelli KB, Fernandes R, Sotomayor EM, Villagra A. HDAC6 plays a non-canonical role in the regulation of anti-tumor immune responses, dissemination, and invasiveness of breast cancer. Cancer Research. PMID 32605998 DOI: 10.1158/0008-5472.Can-19-3738  0.346
2020 Beltrán BE, Villela L, Torres MA, Otero V, Fiad L, Peña C, Cabrera ME, León P, Idrobo H, Castro DA, Paredes S, Perdomo I, Abello V, Rojas C, Ramirez-Ibargüen A, ... ... Sotomayor EM, et al. A Multi-Institutional Validation of the Prognostic Value of the Neutrophil-to-Lymphocyte Ratio in Patients With Diffuse Large B-Cell Lymphoma: A Study From The Latin American Group of Lymphoproliferative Disorders (GELL). Clinical Lymphoma, Myeloma & Leukemia. PMID 32513598 DOI: 10.1016/J.Clml.2020.04.016  0.362
2020 Rao R, Nalluri S, Fiskus W, Savoie A, Buckley KM, Ha K, Balusu R, Joshi A, Coothankandaswamy V, Tao J, Sotomayor E, Atadja P, Bhalla KN. Editor's Note: Role of CAAT/Enhancer Binding Protein Homologous Protein in Panobinostat-mediated Potentiation of Bortezomib-induced Lethal Endoplasmic Reticulum Stress in Mantle Cell Lymphoma Cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 26: 1531. PMID 32169966 DOI: 10.1158/1078-0432.Ccr-20-0412  0.33
2019 Yue L, Sharma V, Horvat NP, Akuffo AA, Beatty MS, Murdun C, Colin C, Billington J, Goodheart WE, Sahakian E, Zhang L, Powers JJ, Amin NE, Lambert-Showers QT, Darville LN, ... ... Sotomayor EM, et al. HDAC11 Deficiency or Inhibition Disrupts Oncogene-Induced Stress Hematopoiesis in Myeloproliferative Neoplasms. Blood. PMID 31750881 DOI: 10.1182/Blood.2019895326  0.4
2019 Beltran BE, Paredes S, Castro D, Cotrina E, Sotomayor EM, Castillo JJ. High Red Cell Distribution Width is an Adverse Predictive and Prognostic Factor in Patients With Diffuse Large B-Cell Lymphoma Treated With Chemoimmunotherapy. Clinical Lymphoma, Myeloma & Leukemia. PMID 31320254 DOI: 10.1016/J.Clml.2019.06.005  0.357
2019 Li W, Gupta SK, Han W, Kundson RA, Nelson S, Knutson D, Greipp PT, Elsawa SF, Sotomayor EM, Gupta M. Targeting MYC activity in double-hit lymphoma with MYC and BCL2 and/or BCL6 rearrangements with epigenetic bromodomain inhibitors. Journal of Hematology & Oncology. 12: 73. PMID 31288832 DOI: 10.1186/S13045-019-0761-2  0.409
2019 Zhao X, Ren Y, Lawlor M, Shah BD, Park PMC, Lwin T, Wang X, Liu K, Wang M, Gao J, Li T, Xu M, Silva AS, Lee K, Zhang T, ... ... Sotomayor EM, et al. BCL2 Amplicon Loss and Transcriptional Remodeling Drives ABT-199 Resistance in B Cell Lymphoma Models. Cancer Cell. 35: 752-766.e9. PMID 31085176 DOI: 10.1016/J.Ccell.2019.04.005  0.341
2019 Kahl BS, Dreyling M, Gordon LI, Martin P, Quintanilla-Martinez L, Sotomayor EM. Recent advances and future directions in mantle cell lymphoma research: report of the 2018 mantle cell lymphoma consortium workshop. Leukemia & Lymphoma. 1-13. PMID 30696305 DOI: 10.1080/10428194.2019.1571205  0.375
2019 Cheng F, Yan D, Chen J, Keidar M, Sotomayor E. Cold Plasma with Immunomodulatory Properties Has Significant Anti-Lymphoma Activities in Vitro and In Vivo Blood. 134: 5307-5307. DOI: 10.1182/Blood-2019-131065  0.473
2019 Sharma V, Yue L, Horvat NP, Christodoulidou A, Akuffo AA, Beatty M, Murdun C, Billington J, Goodheart WE, Sahakian E, Zhang L, Powers JJ, Amin NE, Lambert-Showers QT, Darville L, ... ... Sotomayor E, et al. Selective Targeting of Histone Deacetylase 11 Disables Metabolism of Myeloproliferative Neoplasms Blood. 134: 474-474. DOI: 10.1182/Blood-2019-127235  0.394
2019 Alsharif R, Nassereddine S, Akin E, Karcher D, Smith M, Sotomayor E, Dunleavy K. Short-Course Therapy in Newly Diagnosed Immunodeficiency-Associated Aggressive B-Cell Lymphoma Blood. 134: 5355-5355. DOI: 10.1182/Blood-2019-124081  0.34
2019 M LV, Ramirez-Ibarguen A, Beltrán BE, Otero V, Castro DA, Candelaria M, Pérez-Jacobo F, Montaño Figueroa E, Peña C, Paredes SR, Best C, Gómez-De León A, Gomez-Almaguer D, Ruiz-Arguelles GJ, Idrobo H, ... ... Sotomayor E, et al. Assessment of Different Biological Variables (Serum Albumin, β-2-Microglobulin, Lymphocyte/Monocyte ratio, Neutrophil/Lymphocyte ratio, Platelet/Lymphocyte ratio) in a Retrospective Cohort of 525 Diffuse Large B-Cell Lymphomas As Predictor Factor(s) for Overall Survival Blood. 134: 1613-1613. DOI: 10.1182/Blood-2019-123841  0.304
2019 Idrobo H, Beltrán BE, M LV, Torres Viera M, Otero V, Fiad L, Peña C, Castro DA, Huerta- Collado YM, Paredes SR, Perdomo I, León P, Rojas C, Abello V, Osuna Pérez M, ... ... Sotomayor E, et al. Serum Albumin Is an Independent Factor Predicting Survival in Patients with Peripheral T Cell Lymphoma: A Multi-Institutional Study from the Latin American Working Group for Lymphomas (GELL) Blood. 134: 4047-4047. DOI: 10.1182/Blood-2019-123588  0.312
2019 Malpica Castillo LE, Peña C, Rojas C, León P, Beltrán BE, Castro DA, Huerta- Collado YM, Quinones M, Paredes SR, Idrobo H, Perdomo I, Abello V, Fiad L, Otero V, Torres Viera M, ... ... Sotomayor E, et al. Identifying a Simple Clinical Prognostic Model for Aggressive Adult T-Cell Leukemia/Lymphoma in Latin American Population and Its Validation: A Large International Study of the Latin America Working Group for Lymphomas (GELL) Blood. 134: 4045-4045. DOI: 10.1182/Blood-2019-122976  0.343
2019 Beltrán B, Otero V, Peña C, Fiad L, Mahuad C, Perdomo I, Castro Uriol D, Torres Viera M, Rodriguez M, Chisesi T, Valvert F, Ignacio G, Chiattone C, Villela L, Idrobo H, ... ... Sotomayor E, et al. PRE-TREATMENT SERUM ALBUMIN LEVEL AS A MEANS OF IMPROVING PROGNOSTIC MODELS IN PERIPHERAL T-CELL LYMPHOMAS: A STUDY FROM THE LATIN AMERICAN GROUP OF LYMPHOMAS (GELL) Hematological Oncology. 37: 463-464. DOI: 10.1002/Hon.142_2631  0.369
2018 Maharaj K, Powers JJ, Achille A, Deng S, Fonseca R, Pabon-Saldana M, Quayle SN, Jones SS, Villagra A, Sotomayor EM, Sahakian E, Pinilla-Ibarz J. Silencing of HDAC6 as a therapeutic target in chronic lymphocytic leukemia. Blood Advances. 2: 3012-3024. PMID 30425065 DOI: 10.1182/Bloodadvances.2018020065  0.45
2018 Ren Y, Bi C, Zhao X, Lwin T, Wang C, Yuan J, Silva AS, Shah BD, Fang B, Li T, Koomen JM, Jiang H, Chavez JC, Pham L, Sudalagunta PR, ... ... Sotomayor EM, et al. PLK1 stabilizes a MYC-dependent kinase network in aggressive B cell lymphomas. The Journal of Clinical Investigation. PMID 30260324 DOI: 10.1172/Jci122533  0.371
2018 Castillo JJ, Beltran BE, Miranda RN, Young KH, Chavez JC, Sotomayor EM. EBV-positive diffuse large B-cell lymphoma, not otherwise specified: 2018 update on diagnosis, risk-stratification and management. American Journal of Hematology. 93: 953-962. PMID 29984868 DOI: 10.1002/Ajh.25112  0.336
2018 Beltran BE, Castro D, De La Cruz-Vargas JA, Cotrina E, Gallo A, Sotomayor EM, Castillo JJ. The neutrophil-lymphocyte ratio is prognostic in patients with early stage aggressive peripheral T cell lymphoma. British Journal of Haematology. PMID 29479670 DOI: 10.1111/Bjh.15141  0.399
2018 Beltrán BE, Paredes S, Cotrina E, Sotomayor EM, Castillo JJ. The impact of the neutrophil:lymphocyte ratio in response and survival of patients with de novo diffuse large B-cell lymphoma. Leukemia Research. 67: 82-85. PMID 29477024 DOI: 10.1016/J.Leukres.2018.02.011  0.334
2018 Paredes S, Beltran BE, Sotomayor EM, Castillo JJ, Salas R. High RDW as a predictive and prognostic factor in patients with diffuse large B-cell lymphoma treated with chemoimmunotherapy. Journal of Clinical Oncology. 36: e19547-e19547. DOI: 10.1200/Jco.2018.36.15_Suppl.E19547  0.343
2018 Nogues JC, Wang ZM, Chisholm SS, Smith M, Sotomayor E, Chiappinelli K. The Effect of TET Mutations on DNA Methyltransferase Cytotoxicity and ERV Induction in B and T Cell Malignancies Blood. 132: 5157-5157. DOI: 10.1182/Blood-2018-99-120281  0.373
2018 Mostofa A, Distler A, Meads MB, Sahakian E, Powers JJ, Nguyen T, Alsina M, Nishihori T, Baz R, Pinilla Ibarz J, Sotomayor E, Shain KH, Brayer JB. Functional Analysis of HDAC11 in Plasma Cell Development and Multiple Myeloma Survival Blood. 132: 3223-3223. DOI: 10.1182/Blood-2018-99-119119  0.461
2018 Ren Y, Bi C, Zhao X, Lwin T, Cheng W, Yuan J, Siqueira Silva A, Shah BD, Fang B, Li T, Koomen JM, Jiang H, Chavez JC, Pham LV, Sudalagunta PR, ... ... Sotomayor E, et al. Pharmacoproteomics Identifies PLK1 As Vulnerability for Aggressive B-Cell Lymphomas Blood. 132: 2853-2853. DOI: 10.1182/Blood-2018-99-118004  0.415
2018 Beltrán BE, Castro DA, Vega J, Malaga JM, Postigo M, Gallo A, Sotomayor E, Castillo JJ. The Impact on Survival of EBV Positive Diffuse Large B- Cell Lymphoma, Not Otherwise Specified in Young Adults Blood. 132: 5407-5407. DOI: 10.1182/Blood-2018-99-117662  0.35
2018 Beltrán BE, Castro DA, Huerta- Collado YM, Malaga JM, Postigo M, Sotomayor E, Castillo JJ. Clinical Characteristics and Survival in Patients with EBV Positive Diffuse Large B- Cell Lymphoma, Not Otherwise Specified: Report of 60 Cases Blood. 132: 2986-2986. DOI: 10.1182/Blood-2018-99-117185  0.335
2018 Chen J, Cheng F, Wang M, Sahakian E, Powers JJ, Pinilla Ibarz J, Smith MR, Sotomayor E. Loss of HDAC11 Promotes Myeloid-Derived Suppressor Cells Inhibition of T Cell Function in a Murine Lymphoma Microenvironment Blood. 132: 1105-1105. DOI: 10.1182/Blood-2018-99-117007  0.481
2018 Cheng F, Ren Y, Chen J, Wang Z, Li T, Dunleavy K, Lin J, Bradner J, Smith MR, Shah BD, Sotomayor E, Tao J. C-Myc Driven Tolerogenic Tumor Microenvironment (TME) in Mantle Cell Lymphoma (MCL) Is Overcome By Bromodomain Inhibition Blood. 132: 777-777. DOI: 10.1182/Blood-2018-99-116865  0.429
2018 Zhao X, Jiang H, Wang M, Li T, Gao J, Lwin T, Ren Y, Sotomayor E, Shah BD, Tao J. Targeting Kinome Reprogramming for Overcoming Ibrutinib-Resistance (IR) in Mantle Cell Lymphoma (MCL) Blood. 132: 2651-2651. DOI: 10.1182/Blood-2018-99-116756  0.39
2018 Beltrán BE, Otero V, Torres Viera M, Peña C, Rodriguez ML, Borelli G, Chisesi T, Valvert Gamboa F, Berrios A, Ignacio G, Chiattone CS, Paredes S, Castro DA, Cabrera ME, Gabus R, ... Sotomayor E, et al. The Neutrophil-to-Lymphocyte Ratio Is Prognostic in Patients with Diffuse Large B-Cell Lymphoma: A Study from the Latin American Group of Lymphomas (GELL) Blood. 132: 2987-2987. DOI: 10.1182/Blood-2018-99-113246  0.341
2018 Beltrán BE, Castro DA, Huerta- Collado YM, Sotomayor E, Castillo JJ. RDW Is a Prognostic Marker for Patients with Aggressive Peripheral T-Cell Lymphoma Blood. 132: 5364-5364. DOI: 10.1182/Blood-2018-99-113236  0.413
2018 Beltrán BE, Otero V, Torres Viera M, Peña C, Rodriguez ML, Borelli G, Chisesi T, Valvert Gamboa F, Berrios A, Ignacio G, Chiattone CS, Paredes S, Castro DA, Cabrera ME, Gabus R, ... Sotomayor E, et al. Validation of the Nccn-Ipi for Diffuse Large B-Cell Lymphoma in Latin American Patients: A Study from the Latin-American Group of Lymphomas (GELL) Blood. 132: 5395-5395. DOI: 10.1182/Blood-2018-99-113214  0.338
2018 Beltrán BE, Castro DA, Huerta- Collado YM, Sotomayor E, Castillo JJ. The NCCN-IPI Score Is Prognostic of Survival in Patients with Peripheral T-Cell Lymphoma, Not Otherwise Specified Blood. 132: 5363-5363. DOI: 10.1182/Blood-2018-99-113187  0.345
2018 Chen J, Cheng F, Sahakian E, Powers J, Wang Z, Villagra A, Pinilla-Ibarz J, Sotomayor EM. Abstract 4967: HDAC11 function as a transcriptional regulator in immature myeloid cells to myeloid-derived suppressor cells transition Cancer Research. 78: 4967-4967. DOI: 10.1158/1538-7445.Am2018-4967  0.473
2018 Banik D, Hadley M, Palmer E, Gallub V, Sotomayor E, Kozikowski A, Villagra A. Abstract 48: Targeting HDAC6 to reduce the aggressiveness of metastatic breast cancer in immunotherapy Cancer Research. 78: 48-48. DOI: 10.1158/1538-7445.Am2018-48  0.405
2017 Huang J, Wang L, Dahiya S, Beier UH, Han R, Samanta A, Bergman J, Sotomayor EM, Seto E, Kozikowski AP, Hancock WW. Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function. Scientific Reports. 7: 8626. PMID 28819166 DOI: 10.1038/S41598-017-09211-3  0.346
2017 Beltran BE, Quiñones P, Morales D, Malaga JM, Chavez JC, Sotomayor EM, Castillo JJ. Response and survival benefit with chemoimmunotherapy in Epstein-Barr virus-positive diffuse large B-cell lymphoma. Hematological Oncology. PMID 28639256 DOI: 10.1002/Hon.2449  0.33
2017 Sahakian E, Chen J, Powers JJ, Chen X, Maharaj K, Deng SL, Lienlaf M, Wang HW, Cheng F, Sodré AL, Distler A, Xing L, Perez-Villarroel P, Wei S, Villagra A, ... ... Sotomayor EM, et al. Essential role for histone deacetylase 11 (HDAC11) in neutrophil biology. Journal of Leukocyte Biology. PMID 28550123 DOI: 10.1189/Jlb.1A0415-176Rrr  0.376
2017 Woods DM, Woan KV, Cheng F, Sodré AL, Wang D, Wu Y, Wang Z, Chen J, Powers J, Pinilla-Ibarz J, Yu Y, Zhang Y, Wu X, Zheng X, Weber J, ... ... Sotomayor EM, et al. T-cells lacking HDAC11 have increased effector functions and mediate enhanced alloreactivity in a murine model. Blood. PMID 28550044 DOI: 10.1182/Blood-2016-08-731505  0.467
2017 Zhao X, Lwin T, Silva A, Shah B, Tao J, Fang B, Zhang L, Fu K, Bi C, Li J, Jiang H, Meads MB, Jacobson T, Silva M, Distler A, ... ... Sotomayor E, et al. Unification of de novo and acquired ibrutinib resistance in mantle cell lymphoma. Nature Communications. 8: 14920. PMID 28416797 DOI: 10.1038/Ncomms14920  0.385
2017 Sandoval-Sus J, Sotomayor EM, Shah BD. Mantle cell lymphoma: Contemporary diagnostic and treatment perspectives in the age of personalized medicine. Hematology/Oncology and Stem Cell Therapy. PMID 28404221 DOI: 10.1016/J.Hemonc.2017.02.003  0.352
2017 Kahl BS, Dreyling M, Gordon LI, Quintanilla-Martinez L, Sotomayor EM. Recent advances and future directions in mantle cell lymphoma research: report of the 2016 mantle cell lymphoma consortium workshop. Leukemia & Lymphoma. 1-12. PMID 28140709 DOI: 10.1080/10428194.2017.1283036  0.377
2017 Khushalani NI, Markowitz J, Eroglu Z, Giuroiu I, Ladanova V, Reiersen P, Rich J, Thapa R, Schell MJ, Sotomayor EM, Weber JS. A phase I trial of panobinostat with ipilimumab in advanced melanoma. Journal of Clinical Oncology. 35: 9547-9547. DOI: 10.1200/Jco.2017.35.15_Suppl.9547  0.323
2017 Distler A, Brayer JB, Meads M, Sahakian E, Powers JJ, Alsina M, Nishihori T, Baz RC, Pinilla-Ibarz J, Sotomayor EM, Shain KH. HDAC11 as a candidate therapeutic target in multiple myeloma. Journal of Clinical Oncology. 35: 8029-8029. DOI: 10.1182/Blood.V130.Suppl_1.1800.1800  0.431
2017 Hadley M, Shen S, Banik D, Kim J, Nair J, Knox T, Gallub V, Kirkland S, Chiappinelli KB, Sotomayor E, Kozikowski A, Villagra A. Abstract LB-294:In vivoevaluation of Ames negative HDAC6 inhibitor in melanoma model Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-294  0.387
2017 Cheng F, Andressa S, Chen J, Villagra A, Woods D, Weber J, Quayle S, Simon J, Sotomayor E. Abstract 4976: Ricolinostat, a selective HDAC6 inhibitor with immunomodulatory properties, has significant antimelanoma activity in vitro and in vivo Cancer Research. 77: 4976-4976. DOI: 10.1158/1538-7445.Am2017-4976  0.401
2017 Banik D, Hadley M, Kim J, Knox T, Nair J, Kozikowski A, Shen S, Vyas C, Donohue A, Sotomayor E, Villagra A. Abstract 4854: Evaluating HDAC6 as a causal factor in metastatic breast cancer to develop immunotherapy Cancer Research. 77: 4854-4854. DOI: 10.1158/1538-7445.Am2017-4854  0.393
2017 Knox T, Sahakian E, Nair J, Kim J, Banik D, Hadley M, Powers J, Cheng F, Shen S, Pinilla J, Weber J, Kozikowski A, Sotomayor E, Villagra A. Abstract 4055: Enhancing anti-PD-1 immune blockade in melanoma through selective inhibition of histone deacetylase 6 Cancer Research. 77: 4055-4055. DOI: 10.1158/1538-7445.Am2017-4055  0.345
2016 Castillo JJ, Beltran BE, Miranda RN, Young KH, Chavez JC, Sotomayor EM. EBV-positive diffuse large B-cell lymphoma of the elderly: 2016 update on diagnosis, risk-stratification, and management. American Journal of Hematology. 91: 529-37. PMID 27093913 DOI: 10.1002/Ajh.24370  0.345
2016 Lienlaf M, Perez-Villarroel P, Knox T, Pabon M, Sahakian E, Powers J, Woan KV, Lee C, Cheng F, Deng S, Smalley KS, Montecino M, Kozikowski A, Pinilla-Ibarz J, Sarnaik A, ... ... Sotomayor EM, et al. Essential role of HDAC6 in the regulation of PD-L1 in melanoma. Molecular Oncology. PMID 26775640 DOI: 10.1016/J.Molonc.2015.12.012  0.369
2016 Cheng F, Laino AS, Wang H, Chen J, Villagra A, Woods DM, Weber JS, Quayle S, Jones SS, Sotomayor EM. In vitro and in vivo anti-melanoma activity of ricolinostat, a selective HDAC6 inhibitor with immunomodulatory properties. Journal of Clinical Oncology. 34: e21075-e21075. DOI: 10.1200/Jco.2016.34.15_Suppl.E21075  0.35
2016 Talati C, Sandoval-Sus JD, Dalia S, Shah BD, Bello CM, Chervenick PA, Ayala E, Locke FL, Kharfan-Dabaja MA, Sotomayor EM, Sokol L, Chavez JC. The prognostic impact of serum albumin in double hit/double expressing aggressive B cell lymphomas: A pilot study evaluating SAAB scoring system. Journal of Clinical Oncology. 34: e19044-e19044. DOI: 10.1200/Jco.2016.34.15_Suppl.E19044  0.37
2016 Laino AS, Woods DM, Sarnaik A, Quayle3 S, Jones3 SS, Sotomayor EM, Weber JS. Selective histone deacetylase inhibition augments melanoma immunotherapy. Journal of Clinical Oncology. 34: e14521-e14521. DOI: 10.1200/Jco.2016.34.15_Suppl.E14521  0.347
2016 Sandoval-Sus JD, Dalia S, Talati C, Shah BD, Bello CM, Lancet JE, Chervenick PA, Locke FL, Kharfan-Dabaja M, Sotomayor EM, Sokol L, Chavez JC, Pinilla-Ibarz J. Impact of IgVH mutational status in patients with chronic lymphocytic leukemia with isolated good and intermidiate risk genetic aberrations. Journal of Clinical Oncology. 34: 7534-7534. DOI: 10.1200/Jco.2016.34.15_Suppl.7534  0.331
2016 Chen J, Cheng F, Woods DM, Seto E, Villagra A, Sotomayor EM. Histone Deacetylase 11 (HDAC11) Interaction with Ikaros Represent a Novel Mechanism of Regulation of Essential Transcriptional Factors in CD4+ T Cells Blood. 128: 864-864. DOI: 10.1182/Blood.V128.22.864.864  0.434
2016 Beltran BE, Castro D, Motta R, Paredes S, Malaga JM, Miranda RN, Sotomayor EM, Castillo JJ. The Neutrophil-to-Lymphocyte Ratio Is Prognostic in Patients with Early Stage Peripheral T-Cell Lymphoma Blood. 128: 5346-5346. DOI: 10.1182/Blood.V128.22.5346.5346  0.358
2016 Talati C, Kuykendall A, Kaplan J, Sandoval-Sus JD, Dalia S, Shah BD, Bello CM, Khimani F, Chervenick PA, Ayala E, Locke FL, Kharfan-Dabaja MA, Sotomayor EM, Sokol L, Chavez JC. Impact of Serum Albumin in the Prognosis of Myc-Positive Aggressive B-Cell Lymphomas: Potential for a Novel Prognostic Score Blood. 128: 1870-1870. DOI: 10.1182/Blood.V128.22.1870.1870  0.334
2016 Laino AS, Woods DM, Sarnaik A, Weber J, Sotomayor EM. Abstract A074: Selective Inhibition of HDAC6 augments T-cell central memory and enhances anti-tumor functions: Implications in TIL therapy Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A074  0.459
2016 Woods DM, Sodre AL, Woan K, Villagra A, Sarnaik A, Weber J, Sotomayor EM. Abstract A066: Histone deacetylase 11 is an epigenetic regulator of T-cell pro-inflammatory function and novel target for enhancing T-cell anti-tumor activity Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A066  0.473
2016 Knox T, Lienlaf M, Perez P, Pabon M, Lee C, Cheng F, Sahakian E, Powers J, Deng S, Keiran S, Kozikowski A, Pinilla J, Sarnaik A, Seto E, Weber J, ... Sotomayor E, et al. Abstract 2331: HDAC6, new role as master regulator of PD-L1 and immune-related pathways Cancer Research. 76: 2331-2331. DOI: 10.1158/1538-7445.Am2016-2331  0.349
2016 Sandoval-Sus J, Chavez J, Parra P, Bello C, Chervenick P, Lancet J, Sokol L, Sotomayor E, Locke F, Kharfan-Dabaja M, Shah B, Ayala E. Allogeneic Hematopoietic Stem Cell Transplantation in Mantle Cell Lymphoma: a Single Institution Experience Clinical Lymphoma Myeloma and Leukemia. 16: S115-S116. DOI: 10.1016/J.Clml.2016.07.167  0.315
2016 Talati C, Kuykendall A, Kaplan J, Sandoval-Sus J, Dalia S, Shah B, Bello C, Chervenick P, Ayala E, Locke F, Kharfan-Dabaja M, Sotomayor E, Sokol L, Chavez J. Serum Albumin as Prognostic Factor for Overall Survival in Rearranged MYC and BCL2/BCL6 Positive Double Hit Diffuse Large B Cell Lymphomas Clinical Lymphoma Myeloma and Leukemia. 16: S99. DOI: 10.1016/J.Clml.2016.07.142  0.34
2015 Woods DM, Sodré AL, Villagra A, Sarnaik A, Sotomayor EM, Weber J. HDAC Inhibition Upregulates PD-1 Ligands in Melanoma and Augments Immunotherapy with PD-1 Blockade. Cancer Immunology Research. PMID 26297712 DOI: 10.1158/2326-6066.Cir-15-0077-T  0.355
2015 Horna P, Kurant D, Sokol L, Sotomayor EM, Moscinski L, Glass LF. Flow cytometric identification of immunophenotypically aberrant T-cell clusters on skin shave biopsy specimens from patients with mycosis fungoides. American Journal of Clinical Pathology. 143: 785-96. PMID 25972320 DOI: 10.1309/Ajcpwe2Hbfcgdids  0.391
2015 Woan KV, Lienlaf M, Perez-Villaroel P, Lee C, Cheng F, Knox T, Woods DM, Barrios K, Powers J, Sahakian E, Wang HW, Canales J, Marante D, Smalley KS, Bergman J, ... ... Sotomayor EM, et al. Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation. Molecular Oncology. PMID 25957812 DOI: 10.1016/J.Molonc.2015.04.002  0.463
2015 Kahl BS, Gordon LI, Dreyling M, Gascoyne RD, Sotomayor EM. Advances and issues in mantle cell lymphoma research: report of the 2014 Mantle Cell Lymphoma Consortium Workshop. Leukemia & Lymphoma. 56: 2505-11. PMID 25944379 DOI: 10.3109/10428194.2015.1045903  0.392
2015 Beltran BE, Aguilar C, Quiñones P, Morales D, Chavez JC, Sotomayor EM, Castillo JJ. The neutrophil-to-lymphocyte ratio is an independent prognostic factor in patients with peripheral T-cell lymphoma, unspecified. Leukemia & Lymphoma. 1-5. PMID 25926063 DOI: 10.3109/10428194.2015.1045897  0.352
2015 Demosthenous C, Han JJ, Stenson MJ, Maurer MJ, Wellik LE, Link B, Hege K, Dogan A, Sotomayor E, Witzig T, Gupta M. Translation initiation complex eIF4F is a therapeutic target for dual mTOR kinase inhibitors in non-Hodgkin lymphoma. Oncotarget. 6: 9488-501. PMID 25839159 DOI: 10.18632/Oncotarget.3378  0.365
2015 Sahakian E, Powers JJ, Chen J, Deng SL, Cheng F, Distler A, Woods DM, Rock-Klotz J, Sodre AL, Youn JI, Woan KV, Villagra A, Gabrilovich D, Sotomayor EM, Pinilla-Ibarz J. Histone deacetylase 11: A novel epigenetic regulator of myeloid derived suppressor cell expansion and function. Molecular Immunology. 63: 579-85. PMID 25155994 DOI: 10.1016/J.Molimm.2014.08.002  0.412
2015 Wang H, Cheng F, Cheng J, Villagra A, Tao J, Bradner JE, Sotomayor EM. JQ1, a Selective Bromodomain Inhibitor, Augment the Immunogenicity of Mantle Cell Lymphoma By Influencing the Expression of PD-L1 Blood. 126: 822-822. DOI: 10.1182/Blood.V126.23.822.822  0.523
2015 Beltran BE, Malaga JM, Chavez JC, Sotomayor EM, Castillo JJ. The Neutrophil-Lymphocyte Ratio Is a Prognostic Marker in Patients with EBV-Positive Diffuse Large B-Cell Lymphoma Blood. 126: 5047-5047. DOI: 10.1182/Blood.V126.23.5047.5047  0.356
2015 Sandoval-Sus JD, Chavez JC, Dalia S, Bello CM, Shah BD, Ho VQ, Nodzon L, Kharfan-Dabaja MA, Sotomayor EM, Sokol L, Pinilla-Ibarz J. Outcomes of Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia after Ibrutinib Discontinuation Outside Clinical Trials: A Single Institution Experience Blood. 126: 2945-2945. DOI: 10.1182/Blood.V126.23.2945.2945  0.355
2015 Laino AS, Woods DM, Celis E, Weber J, Sotomayor E. Abstract PR09: Targeting histone deacetylase 6 in T-cells to improve melanoma immunotherapy Cancer Immunology Research. 3. DOI: 10.1158/2326-6074.Tumimm14-Pr09  0.5
2015 Woods DM, Sodre AL, Sarnaik A, Sotomayor EM, Weber J. Abstract 257: Class I HDAC inhibition upregulates PD-1 ligands in melanoma and increases the efficacy of PD-1 blockade Cancer Research. 75: 257-257. DOI: 10.1158/1538-7445.Am2015-257  0.308
2015 Laino AS, Woods DM, Sarnaik A, Celis E, Weber J, Sotomayor EM. Abstract 1338: Novel implications of histone deacetylase 6 selective inhibition in melanoma T-cell immunotherapy Cancer Research. 75: 1338-1338. DOI: 10.1158/1538-7445.Am2015-1338  0.458
2015 Brayer J, Sahakian E, Nguyen D, Powers J, Meads M, Deng S, Distler A, Alsina M, Nishihori T, Baz R, Villagra A, Pinilla-Ibarz J, Sotomayor E, Shain K. Histone deacetylase 11 (HDAC11) is critical for plasma cell development and multiple myeloma survival Clinical Lymphoma Myeloma and Leukemia. 15: e222-e223. DOI: 10.1016/J.Clml.2015.07.478  0.335
2015 Mathew B, Dalia S, Hall J, Shah B, Bello C, Sokol L, Sotomayor E, Chavez J. Analysis of Prognostic Factors in Patients with HIV-Associated Aggressive B-Cell Non-Hodgkin Lymphomas Clinical Lymphoma Myeloma and Leukemia. 15: S230. DOI: 10.1016/J.Clml.2015.04.113  0.337
2014 Cheng F, Lienlaf M, Wang HW, Perez-Villarroel P, Lee C, Woan K, Rock-Klotz J, Sahakian E, Woods D, Pinilla-Ibarz J, Kalin J, Tao J, Hancock W, Kozikowski A, Seto E, ... ... Sotomayor EM, et al. A novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3/IL-10 pathway in APCs. Journal of Immunology (Baltimore, Md. : 1950). 193: 2850-62. PMID 25108026 DOI: 10.4049/Jimmunol.1302778  0.46
2014 Cheng F, Lienlaf M, Perez-Villarroel P, Wang HW, Lee C, Woan K, Woods D, Knox T, Bergman J, Pinilla-Ibarz J, Kozikowski A, Seto E, Sotomayor EM, Villagra A. Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells. Molecular Immunology. 60: 44-53. PMID 24747960 DOI: 10.1016/J.Molimm.2014.02.019  0.424
2014 Kizuka Y, Kitazume S, Okahara K, Villagra A, Sotomayor EM, Taniguchi N. Epigenetic regulation of a brain-specific glycosyltransferase N-acetylglucosaminyltransferase-IX (GnT-IX) by specific chromatin modifiers. The Journal of Biological Chemistry. 289: 11253-61. PMID 24619417 DOI: 10.1074/Jbc.M114.554311  0.307
2014 Dalia S, Chavez J, Little B, Bello C, Fisher K, Lee JH, Chervenick P, Sokol L, Sotomayor E, Shah B. Serum albumin retains independent prognostic significance in diffuse large B-cell lymphoma in the post-rituximab era. Annals of Hematology. 93: 1305-12. PMID 24590536 DOI: 10.1007/S00277-014-2031-2  0.35
2014 Dalia S, Forsyth P, Chavez J, Price S, Shah B, Bello C, Sokol L, Pan E, Sotomayor E, Lee JH, Fisher K, Jaglal M. Primary B-cell CNS lymphoma clinicopathologic and treatment outcomes in 89 patients from a single tertiary care center. International Journal of Hematology. 99: 450-6. PMID 24584873 DOI: 10.1007/S12185-014-1540-Z  0.352
2014 Horna P, Deaver DM, Qin D, Moscinski LC, Sotomayor EM, Glass LF, Sokol L. Quantitative flow cytometric identification of aberrant T cell clusters in erythrodermic cutaneous T cell lymphoma. Implications for staging and prognosis. Journal of Clinical Pathology. 67: 431-6. PMID 24319102 DOI: 10.1136/Jclinpath-2013-201748  0.384
2014 Knox T, Lienlaf M, Perez-Villarroel P, Lee C, Sahakian E, Powers JJ, Cheng F, Canales J, Marante D, Seto E, Sotomayor EM, Villagra A, Horna P. Selective Inhibition of HDAC6 Decreases Viability of Cutaneous T-Cell Lymphoma and Improves Immune Recognition Blood. 124: 5423-5423. DOI: 10.1182/Blood.V124.21.5423.5423  0.45
2014 Beltran BE, Chavez JC, Sotomayor EM, Castillo JJ. Lymphopenia Is an Adverse Prognostic Factor in EBV-Positive Diffuse Large B-Cell Lymphoma Blood. 124: 5408-5408. DOI: 10.1182/Blood.V124.21.5408.5408  0.362
2014 Cheng F, Xia B, Sahakian E, Lwin T, Wang H, Xing L, Shah BD, PerezVillarroel P, LienlafMoreno M, Zhang Y, Quayle SN, Jones SS, Pinilla-Ibarz J, Villagra A, Sotomayor EM, et al. Selective Inhibition of Histone Deacetylase 6 (HDAC6) and HDAC3 As a Novel Therapeutic Strategy in Mantle Cell Lymphoma (MCL) Blood. 124: 5397-5397. DOI: 10.1182/Blood.V124.21.5397.5397  0.442
2014 Brayer JB, Sahakian E, Powers J, Meads MB, Deng S, Distler A, Alsina M, Nishihori T, Baz R, Villagra A, Pinilla-Ibarz J, Sotomayor EM, Shain KH. A Novel Role for Histone Deacetylase 11 (HDAC11) in B Cell Lymphopoiesis and Plasma Cell Survival in Multiple Myeloma Blood. 124: 4715-4715. DOI: 10.1182/Blood.V124.21.4715.4715  0.438
2014 Griffin PT, Chavez JC, Bello CM, Sokol L, Chervenick PA, Ayala E, Tao J, Sotomayor EM, Shah BD. Increased Treatment Intensity Is Not Associated with a Survival Benefit in Patients with Low and Intermediate Risk Mantle Cell Lymphoma, a Retrospective Analysis Blood. 124: 4424-4424. DOI: 10.1182/Blood.V124.21.4424.4424  0.342
2014 Powers JJ, Maharaj KK, Sahakian E, Xing L, PerezVillarroel P, Knox T, Quayle S, Jones SS, Villagra A, Sotomayor EM, Pinilla-Ibarz J. Histone Deacetylase 6 (HDAC6) As a Regulator of Immune Check-Point Molecules in Chronic Lymphocytic Leukemia (CLL) Blood. 124: 3311-3311. DOI: 10.1182/Blood.V124.21.3311.3311  0.457
2014 Shah BD, Tao J, Chervenick PA, Riches ML, Pinilla-Ibarz J, Moscinski LC, Antonia S, Sotomayor EM, Dessureault S. Seven Year Followup for Bystander Vaccine Therapy in Mantle Cell Lymphoma (MCL) Blood. 124: 3083-3083. DOI: 10.1182/Blood.V124.21.3083.3083  0.348
2014 Griffin PT, Dalia S, Shah BD, Sokol L, Bello CM, Chervenick PA, Sotomayor EM, Chavez JC. Multivariate Survival Analysis of Transformed Lymphoma in the Chemoimmunotherapy Era: Impact of the NCCN International Prognostic Index Blood. 124: 2981-2981. DOI: 10.1182/Blood.V124.21.2981.2981  0.305
2014 Chen J, Sahakian E, Powers JJ, LienlafMoreno M, Xing L, Deng S, Distler A, Cheng F, Villagra A, Horna P, Sotomayor EM, Pinilla-Ibarz J. Histone Deacetylase 11 (HDAC11) As a Novel Transcriptional Regulator of C/EBP-β, in Immature Myeloid Cell to Myeloid Derived Suppressor Cell Transition Blood. 124: 225-225. DOI: 10.1182/Blood.V124.21.225.225  0.398
2014 Beltran BE, Castro D, Chavez JC, Sotomayor EM, Castillo JJ. The Prognostic Value of the Neutrophil to Lymphocyte Ratio in 209 Patients with Peripheral T-Cell Lymphoma Blood. 124: 1675-1675. DOI: 10.1182/Blood.V124.21.1675.1675  0.398
2014 Woods DM, Sodre AL, Brayer JB, Sotomayor EM. Abstract 643: The histone deacetylase inhibitor Quisinostat augments the anti-tumor reponses of T-cells: Implications in adoptive cell therapy Cancer Research. 74: 643-643. DOI: 10.1158/1538-7445.Am2014-643  0.497
2014 Sahakian E, Brayer J, Powers J, Meads M, Deng S, Distler A, Alsina M, Nishihori T, Baz R, Villagra A, Pinilla-Ibarz J, Sotomayor E, Shain K. Abstract 5537: Histone deacetylase 11 (HDAC11) regulates B cell lymphopoiesis and potentiates plasma cell survival in multiple myeloma Cancer Research. 74: 5537-5537. DOI: 10.1158/1538-7445.Am2014-5537  0.45
2014 Woods DM, Sodre AL, Sahakian E, Powers J, Lienlaf-Moreno M, Perez-Villarroel P, Villagra A, Pinilla-Ibarz J, Sotomayor E. Abstract 4090: Inhibition of class I histone deacetylases promotes robust and durable enhancement of PDL1 expression in melanoma: Rationale for combination therapy Cancer Research. 74: 4090-4090. DOI: 10.1158/1538-7445.Am2014-4090  0.421
2014 Lienlaf M, Perez-Villarroel P, Lee C, Cheng F, Canales J, Knox T, Marante D, Sarnaik A, Horna P, Seto E-, Smalley K, Weber JS, Sotomayor EM, Villagra A. Abstract 4089: Histone deacetylase 6 (HDAC6) as a regulator of PD-L1 expression through STAT3 modulation in melanoma Cancer Research. 74: 4089-4089. DOI: 10.1158/1538-7445.Am2014-4089  0.387
2014 Perez-Villarroel P, Lienlaf M, Lee C, Cheng F, Woods D, Barrios K, Woan K, Canales J, Knox T, Marante D, Wang H, Horna P, Smalley K, Celis E, Seto E, ... ... Sotomayor EM, et al. Abstract 4086: Histone deacetylase 6 (HDAC6) as a new target modulating the proliferation and immune-related pathways in melanoma Cancer Research. 74: 4086-4086. DOI: 10.1158/1538-7445.Am2014-4086  0.462
2014 Laino AS, Woods DM, Cheng F, Wang H, Sotomayor EM. Abstract 2564: Histone deacetylase 6 is a novel target for enhancing T-cell function during anti-tumor response and tumor-peptide vaccination Cancer Research. 74: 2564-2564. DOI: 10.1158/1538-7445.Am2014-2564  0.467
2014 Woods DM, Laino A, Villagra A, Sotomayor EM. Molecular pathways in antigen-presenting cells involved in the induction of antigen-specific T-cell tolerance Tumor-Induced Immune Suppression: Mechanisms and Therapeutic Reversal. 411-433. DOI: 10.1007/978-1-4899-8056-4_15  0.31
2013 Lwin T, Zhao X, Cheng F, Zhang X, Huang A, Shah B, Zhang Y, Moscinski LC, Choi YS, Kozikowski AP, Bradner JE, Dalton WS, Sotomayor E, Tao J. A microenvironment-mediated c-Myc/miR-548m/HDAC6 amplification loop in non-Hodgkin B cell lymphomas. The Journal of Clinical Investigation. 123: 4612-26. PMID 24216476 DOI: 10.1172/Jci64210  0.415
2013 Woods DM, Woan K, Cheng F, Wang H, Perez-Villarroel P, Lee C, Lienlaf M, Atadja P, Seto E, Weber J, Sotomayor EM, Villagra A. The antimelanoma activity of the histone deacetylase inhibitor panobinostat (LBH589) is mediated by direct tumor cytotoxicity and increased tumor immunogenicity. Melanoma Research. 23: 341-8. PMID 23963286 DOI: 10.1097/Cmr.0B013E328364C0Ed  0.449
2013 Zhao X, Lwin T, Zhang X, Huang A, Wang J, Marquez VE, Chen-Kiang S, Dalton WS, Sotomayor E, Tao J. Disruption of the MYC-miRNA-EZH2 loop to suppress aggressive B-cell lymphoma survival and clonogenicity. Leukemia. 27: 2341-50. PMID 23538750 DOI: 10.1038/Leu.2013.94  0.326
2013 Youn JI, Kumar V, Collazo M, Nefedova Y, Condamine T, Cheng P, Villagra A, Antonia S, McCaffrey JC, Fishman M, Sarnaik A, Horna P, Sotomayor E, Gabrilovich DI. Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer. Nature Immunology. 14: 211-20. PMID 23354483 DOI: 10.1038/Ni.2526  0.388
2013 Zhang L, Sotomayor EM, Papenhausen PR, Shao H, Moscinski LC, Sandin RL, Caceres G, Valenica H, Malafa M, List AF, Sokol L. Unusual concurrence of T-cell large granular lymphocytic leukemia with Franklin disease (gamma heavy chain disease) manifested with massive splenomegaly. Leukemia & Lymphoma. 54: 205-8. PMID 22694793 DOI: 10.3109/10428194.2012.697561  0.347
2013 Dalia S, Brayer JB, Chavez JC, Bello CM, Shah BD, Horna P, Zhang H, Sokol L, Sotomayor EM, Pinilla-Ibarz J. Concurrent Epstein Barr Virus Viremia and Hodgkin Lymphoma In Two Patients With Chronic Lymphocytic Leukemia Blood. 122: 5290-5290. DOI: 10.1182/Blood.V122.21.5290.5290  0.375
2013 Dalia S, Chavez JC, Bello CM, Chervenick PA, Sokol L, Tao J, Sotomayor EM, Shah BD. Locally Directed Therapy In Limited Stage Mantle Cell Lymphoma Blood. 122: 5057-5057. DOI: 10.1182/Blood.V122.21.5057.5057  0.326
2013 Chen J, Powers J, Rock-Klotz J, Deng S, Distler A, Cheng F, Villagra A, Sotomayor EM, Sahakian E, Pinilla-Ibarz J. Histone Deacetylase 11 (HDAC11) Is a Novel Regulator In The Expansion Of MDSCs Via The Transcription Factor C/EBP-β Blood. 122: 4887-4887. DOI: 10.1182/Blood.V122.21.4887.4887  0.372
2013 Christina T, Dalia S, Bello CM, Sokol L, Sotomayor EM, Shah BD, Chavez JC. The Revised International Prognostic Index (R-IPI) Score Is Predictive Of Survival In Aggressive Transformed Lymphomas (TL) From Low Grade Non-Hodgkin Lymphomas In The Chemoimmunotherapy Era Blood. 122: 4275-4275. DOI: 10.1182/Blood.V122.21.4275.4275  0.33
2013 Dalia S, Chavez JC, Bello CM, Chervenick PA, Little BJ, Al Ali NH, Sokol L, Sotomayor EM, Lee J, Fisher K, Thompson Z, Choi B, Shah BD. A New Prognostic Index In Diffuse Large B-Cell Lymphoma Using Serum Albumin: A Pilot Study Evaluating The Albumin Adjusted-International Prognostic Index (A-IPI) Blood. 122: 4267-4267. DOI: 10.1182/Blood.V122.21.4267.4267  0.321
2013 Tao J, Shah BD, Zhang X, Rastogi P, Tao J, Lancet JE, Nieder M, Lin H, Sotomayor EM, Moscinski L, Zhang L. Expression Level Of p-STAT5, c-MYC and IKZF1 By Immunohistochemistry Might Correlate With Adverse Clinic Outcome In Adult B- Lymphoblastic Leukemia (B-ALL) Blood. 122: 3875-3875. DOI: 10.1182/Blood.V122.21.3875.3875  0.329
2013 Sahakian E, Powers J, Chen J, Distler A, Rock-Klotz J, Deng S, Wei S, Sotomayor EM, Pinilla-Ibarz J, Horna P. A Novel Role For Histone Deacetylase 11 (HDAC11) As a Regulator Of Neutrophil Function and Differentiation In Normal and Malignant Hematopoesis Blood. 122: 2267-2267. DOI: 10.1182/Blood.V122.21.2267.2267  0.442
2013 Sahakian E, Brayer JB, Powers J, Meads M, Distler A, Deng S, Alsina M, Nishihori T, Baz R, Pinilla-Ibarz J, Sotomayor EM, Shain K. A Novel Role For Histone Deacetylase 11 (HDAC11) In Plasma Cell Differentation and Survival Blood. 122: 1907-1907. DOI: 10.1182/Blood.V122.21.1907.1907  0.42
2013 Wu H, Bui M, Shao H, Sokol L, Sotomayor EM, Bulkeley W, Zhang L. Prognostic Significance Of Soft Tissue Involvement and International Prognostic Index In Primary Bone Lymphoma– A Single Institutional Experience Blood. 122: 1781-1781. DOI: 10.1182/Blood.V122.21.1781.1781  0.311
2013 Little BJ, Chavez JC, Bello CM, Chervenick P, Sokol L, Sotomayor EM, Shah BD. A Retrospective Evaluation Of Insurance Status As It Relates To Outcomes In Diffuse Large B-Cell Lymphoma Blood. 122: 1702-1702. DOI: 10.1182/Blood.V122.21.1702.1702  0.326
2013 Laino AS, Woods DM, Cheng F, Wang H, Sotomayor EM. Histone Deacetylase 6 (HDAC6) Influences T-Cell Activation and Survival: Implications For Cancer Immunotherapy Blood. 122: 1050-1050. DOI: 10.1182/Blood.V122.21.1050.1050  0.481
2013 Lienlaf M, Perez-Villarroel P, Cheng F, Lee CK, Canales J, Knox T, Marante D, Yoder SJ, Woan KV, Pinilla-Ibarz J, Seto E, Sotomayor EM, Villagra A. Role Of Histone Deacetylase 6 (HDAC6) In The Modulation Of STAT Pathways and Immune Function Of APCs Blood. 122: 1032-1032. DOI: 10.1182/Blood.V122.21.1032.1032  0.443
2013 Woods DM, Woan K, Cheng F, Wang HW, Sahakian E, Powers J, Rock-Klotz J, Villagra A, Pinilla-Ibarz J, Sotomayor E. Abstract 692: Histone deacetylase 11 is an epigenetic regulator of CD8+ T-cell effector function and memory formation. Cancer Research. 73: 692-692. DOI: 10.1158/1538-7445.Am2013-692  0.459
2013 Tao J, Lwin T, Zhao X, Shah B, Zhang L, Moscinski L, Dalton W, Sotomayor EM, Tao J. Abstract 4944: Combined treatment of BTK and PI3K inhibitors synergistically disrupts BCR-signaling, overcomes microenviroment-mediated survival and drug resistance in mantle cell lymphoma. Cancer Research. 73: 4944-4944. DOI: 10.1158/1538-7445.Am2013-4944  0.449
2013 Horna P, Deaver DM, Moscinski LC, Sotomayor EM, Glass F, Sokol L. Quantitative Flow Cytometric Analysis in Erythrodermic Cutaneous T-Cell Lymphoma: Implications for Prognosis and Staging American Journal of Clinical Pathology. 140: A216-A216. DOI: 10.1093/Ajcp/140.Suppl1.216  0.341
2012 Bergman JA, Woan K, Perez-Villarroel P, Villagra A, Sotomayor EM, Kozikowski AP. Selective histone deacetylase 6 inhibitors bearing substituted urea linkers inhibit melanoma cell growth. Journal of Medicinal Chemistry. 55: 9891-9. PMID 23009203 DOI: 10.1021/Jm301098E  0.339
2012 Fiskus W, Rao R, Balusu R, Ganguly S, Tao J, Sotomayor E, Mudunuru U, Smith JE, Hembruff SL, Atadja P, Marquez VE, Bhalla K. Superior efficacy of a combined epigenetic therapy against human mantle cell lymphoma cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 6227-38. PMID 22932665 DOI: 10.1158/1078-0432.Ccr-12-0873  0.397
2012 Cheng F, Wang H, Horna P, Wang Z, Shah B, Sahakian E, Woan KV, Villagra A, Pinilla-Ibarz J, Sebti S, Smith M, Tao J, Sotomayor EM. Stat3 inhibition augments the immunogenicity of B-cell lymphoma cells, leading to effective antitumor immunity. Cancer Research. 72: 4440-8. PMID 22728650 DOI: 10.1158/0008-5472.Can-11-3619  0.482
2012 Shah BD, Martin P, Sotomayor EM. Mantle cell lymphoma: a clinically heterogeneous disease in need of tailored approaches. Cancer Control : Journal of the Moffitt Cancer Center. 19: 227-35. PMID 22710898 DOI: 10.1177/107327481201900307  0.357
2012 Kriss CL, Pinilla-Ibarz JA, Mailloux AW, Powers JJ, Tang CH, Kang CW, Zanesi N, Epling-Burnette PK, Sotomayor EM, Croce CM, Del Valle JR, Hu CC. Overexpression of TCL1 activates the endoplasmic reticulum stress response: a novel mechanism of leukemic progression in mice. Blood. 120: 1027-38. PMID 22692508 DOI: 10.1182/Blood-2011-11-394346  0.372
2012 Woan KV, Sahakian E, Sotomayor EM, Seto E, Villagra A. Modulation of antigen-presenting cells by HDAC inhibitors: implications in autoimmunity and cancer. Immunology and Cell Biology. 90: 55-65. PMID 22105512 DOI: 10.1038/Icb.2011.96  0.404
2012 Zhang X, Chen X, Lin J, Lwin T, Wright G, Moscinski LC, Dalton WS, Seto E, Wright K, Sotomayor E, Tao J. Myc represses miR-15a/miR-16-1 expression through recruitment of HDAC3 in mantle cell and other non-Hodgkin B-cell lymphomas. Oncogene. 31: 3002-8. PMID 22002311 DOI: 10.1038/Onc.2011.470  0.304
2012 Bai F, Villagra AV, Zou J, Painter JS, Connolly K, Blaskovich MA, Sokol L, Sebti S, Djeu JY, Loughran TP, Wei S, Sotomayor E, Epling-Burnette P. Tipifarnib-mediated suppression of T-bet-dependent signaling pathways. Cancer Immunology, Immunotherapy : Cii. 61: 523-33. PMID 21983879 DOI: 10.1007/S00262-011-1109-0  0.444
2012 Jaglal M, Peker D, Bello CM, Shah BD, Sokol L, Zhang L, Sotomayor EM, Tao J, Cultrera JL. A review of clinicopathologic characteristics, therapy, and outcomes of 22 patients with aggressive B-cell lymphoma. Journal of Clinical Oncology. 30: e21123-e21123. DOI: 10.1200/Jco.2012.30.15_Suppl.E21123  0.358
2012 Freyer C, George T, Price S, Shah BD, Bello CM, Sokol L, Sotomayor EM, Cultrera JL. R-ICE versus R-ESHAP for salvage therapy in aggressive B-cell non-Hodgkin lymphoma. Journal of Clinical Oncology. 30: e18509-e18509. DOI: 10.1200/Jco.2012.30.15_Suppl.E18509  0.341
2012 Kubal TE, Peker D, Sagatys E, Zhang L, Naghashpour M, Moscinski L, Sotomayor EM, Sokol L, Bello CM, Cultrera JL, Chervenick PA, Shah BD. Natural history and clinical prognosis of in situ mantle cell lymphoma. Journal of Clinical Oncology. 30: e18506-e18506. DOI: 10.1200/Jco.2012.30.15_Suppl.E18506  0.36
2012 Peker D, Kubal TE, Sotomayor EM, Sokol L, Cultrera JL, Bello CM, Chervenick PA, Sagatys E, Naghashpour M, Zhang L, Moscinski L, Shah BD. Unusual primary presentations of mantle cell lymphoma in the urinary tract and testes. Journal of Clinical Oncology. 30: e18503-e18503. DOI: 10.1200/Jco.2012.30.15_Suppl.E18503  0.376
2012 Crescentini RM, Sweet KL, Liu J, Liboy I, Dalia S, Chavez JC, Bello CM, Sokol L, Sotomayor EM, Cabanillas F, Cultrera JL. An update on gemcitabine, rituximab, and oxaliplatin in combination for relapsed/refractory non-Hodgkin lymphomas. Journal of Clinical Oncology. 30: 8084-8084. DOI: 10.1200/Jco.2012.30.15_Suppl.8084  0.387
2012 Chavez JC, Domingo G, Dalia S, Dubovsky JA, Berchmans E, Powers JJ, Sweet KL, Crescentini RM, Sotomayor EM, Komrokji RS, Pinilla-Ibarz J. Cancer testicular antigens as a prognostic markers of chronic lymphocytic leukemia. Journal of Clinical Oncology. 30: 6575-6575. DOI: 10.1200/Jco.2012.30.15_Suppl.6575  0.358
2012 Dalia S, Chavez JC, Domingo G, Carballido EM, Aguayo-Hiraldo PI, Sweet KL, Crescentini RM, Sokol L, Bello CM, Cultrera JL, Shah BD, Lancet JE, Komrokji RS, Sotomayor EM, Pinilla-Ibarz J. Incidence of second and secondary malignancies in patients with CLL: A single institution experience. Journal of Clinical Oncology. 30: 6568-6568. DOI: 10.1200/Jco.2012.30.15_Suppl.6568  0.329
2012 Hasija N, Jaglal M, Duong V, Bello CM, Tomblyn MB, Forsyth PAJ, Sotomayor EM, Pan E, Sokol L. Primary CNS lymphoma: A review of clinicopathologic characteristics, therapy, and outcomes of 54 patients with primary CNS DLBCL. Journal of Clinical Oncology. 30: 2099-2099. DOI: 10.1200/Jco.2012.30.15_Suppl.2099  0.337
2012 Woods DM, Woan KV, Sahakian E, Powers J, Cheng F, Wang H, Rock-Klotz J, Weber JS, Villagra A, Pinilla-Ibarz J, Sotomayor EM. Histone Deacetylase 11 (HDAC11) Regulates Cytotoxic T-Cell Function and Memory Phenotype Blood. 120: 840-840. DOI: 10.1182/Blood.V120.21.840.840  0.484
2012 Cheng F, Wang Z, Wang H, Lienlaf M, Woan KV, Perez-Villarroel P, Rock-Klotz J, Sahakian E, Knox T, Woods DM, Powers J, Han R, Merino O, Deng S, Marante D, ... ... Sotomayor EM, et al. Physical Interaction of Histone Deacetylase 6 (HDAC6) with STAT3 Regulates IL-10 Gene Expression and Immune Tolerance Mediated by Antigen-Presenting Cells (APCs) Blood. 120: 829-829. DOI: 10.1182/Blood.V120.21.829.829  0.494
2012 Lwin T, Zhao X, Cheng F, Zhang X, Zhang Y, Huang A, Moscinski L, Dalton WS, Sotomayor EM, Tao J. Targeting Mir-548m-HDAC6 Axis Circumvents Stroma- Mediated Drug Resistance (CAM-DR) and Clonogenicity in Non-Hodgkin B-Cell Lymphomas Blood. 120: 5094-5094. DOI: 10.1182/Blood.V120.21.5094.5094  0.401
2012 Shah BD, Martin P, Cultrera JL, Bello CM, Sokol L, Sotomayor EM. Time to Treatment of Greater Than 1 Year Optimally Stratifies Patients with Improved Survival in Mantle Cell Lymphoma Blood. 120: 5082-5082. DOI: 10.1182/Blood.V120.21.5082.5082  0.338
2012 Tao J, Lwin T, Zhao X, Zhang L, Moscinski L, Sotomayor EM, Dalton WS, Tao J. B Cell Receptor (BCR) Signal Pathways Confer Microenvironment-Mediated Drug Resistance and Are Promising Therapeutic Targets for B Cell Lymphomas Blood. 120: 4918-4918. DOI: 10.1182/Blood.V120.21.4918.4918  0.403
2012 Jaglal MV, Shah BD, Cultrera JL, Sotomayor EM, Tomblyn MB, Bello CM, Sokol L. Primary CNS Lymphoma in a HIV Negative Population: A Review of Clinicopathologic Characteristics, Therapy, and Outcomes of 59 Patients Blood. 120: 4858-4858. DOI: 10.1182/Blood.V120.21.4858.4858  0.35
2012 Li X, Xia B, Guo S, Sotomayor EM, Yu Y, Yang H, Zhao H, Zhao Z, Wang X, Wang Y, Zhang Y. A Retrospective Analysis of Gastric Diffuse Large B-Cell Lymphoma with or without MALT Component Blood. 120: 4856-4856. DOI: 10.1182/Blood.V120.21.4856.4856  0.326
2012 Sahakian E, Powers J, Horna P, Rock-Klotz J, Deng S, Woods DM, Nguyen M, Woan KV, Cheng F, Villagra A, Gabrilovich D, Sotomayor EM, Pinilla-Ibarz J. Novel Role of Histone Deacetylase 11 (HDAC11) in Hematopoiesis Blood. 120: 4728-4728. DOI: 10.1182/Blood.V120.21.4728.4728  0.428
2012 Xia B, Li X, Zhang L, Guo Q, Jin X, Guo S, Sotomayor EM, Zhang Y. BTK inhibitor PCI-32765 targets endogenous and microenvironment-mediated B-cell receptor signaling to suppress lymphoma cell growth and is highly synergistic with Bortezmib against non-Hodgkin B-cell lymphomas Blood. 120: 4721-4721. DOI: 10.1182/Blood.V120.21.4721.4721  0.441
2012 Zhao X, Lwin T, Zhang X, Huang A, Wang J, Marquez VE, Chen-Kiang S, Bradner JE, Dalton WS, Sotomayor EM, Tao J. Silencing c-Myc Using Myc Inhibitor JQ1 and EZH2 Inhibitor DZNep Blocks Converging Survival Signals in Aggressive B-Cell Lymphomas Blood. 120: 4618-4618. DOI: 10.1182/Blood.V120.21.4618.4618  0.354
2012 Shah BD, Little BJ, Cultrera J, Bello CM, Sokol L, Sotomayor EM, Tomblyn M, Ayala E. Cytarabine Either with Induction or Conditioning May Improve Outcomes Among Those Undergoing Autologous Transplantation in First or Second Remission for Mantle Cell Lymphoma Blood. 120: 4546-4546. DOI: 10.1182/Blood.V120.21.4546.4546  0.305
2012 Wang H, Cheng F, Wang Z, Lienlaf M, Perez-Villarroel P, Knox T, Sahakian E, Pinilla-Ibarz J, Horna P, Chen-Kiang S, Martin P, Bergman J, Kozikowski A, Villagra A, Tao J, ... ... Sotomayor EM, et al. Inhibition of Histone Deacetylase 6 (HDAC6) Disrupts the Tolerogenic STAT3 Signaling Pathway and Augments Antitumor Immune Responses in Mantle Cell Lymphoma (MCL) Blood. 120: 3724-3724. DOI: 10.1182/Blood.V120.21.3724.3724  0.519
2012 Sahakian E, Rock-Klotz J, Shah BD, Powers J, Cultrera JL, Deng S, Woods DM, Nguyen M, Cheng F, Wang H, Perez-Villarroel P, Lienlaf M, Knox T, Chen-Kiang S, Villagra A, ... ... Sotomayor EM, et al. Combination of ACY1215, a Selective Histone Deacetylase 6 (HDAC6) Inhibitor with the Bruton Tyrosine Kinase (BTK) Inhibitor, Ibrutinib, Represents a Novel Therapeutic Strategy in Mantle Cell Lymphoma (MCL) Blood. 120: 1660-1660. DOI: 10.1182/Blood.V120.21.1660.1660  0.445
2012 Lienlaf M, Perez-Villarroel P, Cheng F, Wang H, Marante D, Yoder S, V. WK, Knox T, Lagor S, Pinilla-Ibarz J, Seto E, Sotomayor EM, Villagra A. Critical Role for Histone Deacetylase 6 (HDAC6) in the Regulation of IL-6, and the JAK/STA3 Signaling Cascade in Macrophages Blood. 120: 1039-1039. DOI: 10.1182/Blood.V120.21.1039.1039  0.437
2012 Sahakian E, Powers J, Rock-Klotz J, Marsilio A, Woan K, Merino O, Gill A, Deng S, Cheng F, Villagra A, Luekette N, Seto E, Borrello I, Sotomayor E, Pinilla JI. Abstract 4260: Histone deacetylase 11 (HDAC11) as a novel therapeutic target in the regulation of myeloid-derived suppressor cell (MDSC) Cancer Research. 72: 4260-4260. DOI: 10.1158/1538-7445.Am2012-4260  0.443
2012 Woan KV, Vazquez L, Rock-Klotz J, Wang Z, Cheng F, Wang H, Woods D, Sahakian E, Perez P, Lienlaf M, Achille A, Bergman J, Kalin J, Gill A, Powers J, ... ... Sotomayor EM, et al. Abstract 3555: Histone deacetylase 6 as a novel regulator of the immunogenicity and aggressiveness of melanoma Cancer Research. 72: 3555-3555. DOI: 10.1158/1538-7445.Am2012-3555  0.474
2012 Woods DM, Woan KV, Wang H, Cheng F, Wang Z, Vazquez L, Perez P, Lienlaf M, Rock-Klotz J, Sahakian E, Powers J, Deng S, Oscar M, Atadja P, Seto E, ... ... Sotomayor EM, et al. Abstract 3554: The histone deacetylase inhibitor LBH589 augments anti-tumor immunity through direct effects on tumor and immune cells leading to impaired tumor progressionin vivo Cancer Research. 72: 3554-3554. DOI: 10.1158/1538-7445.Am2012-3554  0.479
2011 Castillo JJ, Beltran BE, Morales D, Quinones P, Miranda R, Gallo A, Lopez-Ilasaca M, Desposorio CR, Hurtado de Mendoza F, Sotomayor EM. EBV-positive diffuse large B-cell lymphoma of the elderly in Peru: Report of 33 cases. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: e18538. PMID 28023289 DOI: 10.1200/Jco.2011.29.15_Suppl.E18538  0.349
2011 Beltran BE, Castillo JJ, Morales D, de Mendoza FH, Quinones P, Miranda RN, Gallo A, Lopez-Ilasaca M, Butera JN, Sotomayor EM. EBV-positive diffuse large B-cell lymphoma of the elderly: a case series from Peru. American Journal of Hematology. 86: 663-7. PMID 21761432 DOI: 10.1002/Ajh.22078  0.373
2011 Liu JJ, Zhang L, Ayala E, Field T, Ochoa-Bayona JL, Perez L, Bello CM, Chervenick PA, Bruno S, Cultrera JL, Baz RC, Kharfan-Dabaja MA, Raychaudhuri J, Sotomayor EM, Sokol L. Human immunodeficiency virus (HIV)-negative plasmablastic lymphoma: a single institutional experience and literature review. Leukemia Research. 35: 1571-7. PMID 21752466 DOI: 10.1016/J.Leukres.2011.06.023  0.315
2011 Komrokji RS, Al Ali NH, Beg MS, Safa MM, Rollison D, Kharfan-Dabaja M, Bello C, Cultrera J, Sokol L, Pinilla-Ibarz J, Sotomayor EM. Outcome of diffuse large B-Cell lymphoma in the United States has improved over time but racial disparities remain: review of SEER data. Clinical Lymphoma, Myeloma & Leukemia. 11: 257-60. PMID 21658652 DOI: 10.1016/J.Clml.2011.03.012  0.308
2011 Schuster SJ, Neelapu SS, Gause BL, Janik JE, Muggia FM, Gockerman JP, Winter JN, Flowers CR, Nikcevich DA, Sotomayor EM, McGaughey DS, Jaffe ES, Chong EA, Reynolds CW, Berry DA, et al. Vaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 2787-94. PMID 21632504 DOI: 10.1200/Jco.2010.33.3005  0.322
2011 Dubovsky JA, Powers JJ, Gao Y, Mariusso LF, Sotomayor EM, Pinilla-Ibarz JA. Epigenetic repolarization of T lymphocytes from chronic lymphocytic leukemia patients using 5-aza-2'-deoxycytidine. Leukemia Research. 35: 1193-9. PMID 21377729 DOI: 10.1016/J.Leukres.2011.02.007  0.449
2011 Wang H, Cheng F, Woan K, Sahakian E, Merino O, Rock-Klotz J, Vicente-Suarez I, Pinilla-Ibarz J, Wright KL, Seto E, Bhalla K, Villagra A, Sotomayor EM. Histone deacetylase inhibitor LAQ824 augments inflammatory responses in macrophages through transcriptional regulation of IL-10. Journal of Immunology (Baltimore, Md. : 1950). 186: 3986-96. PMID 21368229 DOI: 10.4049/Jimmunol.1001101  0.804
2011 Powers JJ, Dubovsky JA, Epling-Burnette PK, Moscinski L, Zhang L, Mustjoki S, Sotomayor EM, Pinilla-Ibarz JA. A molecular and functional analysis of large granular lymphocyte expansions in patients with chronic myelogenous leukemia treated with tyrosine kinase inhibitors. Leukemia & Lymphoma. 52: 668-79. PMID 21271862 DOI: 10.3109/10428194.2010.550074  0.419
2011 Beltran BE, Castillo JJ, Salas R, Quiñones P, Morales D, Cotrina E, Miranda RN, Sotomayor EM. Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone: report of two cases from South America. Leukemia & Lymphoma. 52: 153-6. PMID 21219127 DOI: 10.3109/10428194.2010.528094  0.376
2011 Dubovsky JA, Wang D, Powers JJ, Berchmans E, Smith MA, Wright KL, Sotomayor EM, Pinilla-Ibarz JA. Restoring the functional immunogenicity of chronic lymphocytic leukemia using epigenetic modifiers. Leukemia Research. 35: 394-404. PMID 20863567 DOI: 10.1182/Blood.V114.22.5116.5116  0.499
2011 Wang H, Wang Z, Cheng F, Woan KV, Rock-Klotz J, Sahakian E, Powers J, Javier P, Bergman J, Villagra A, Kozikowski A, Sotomayor EM. Tubastatin A, a Selective HDAC6 Inhibitor, Enhances Antigen-Presenting Cell (APC) Function and Restores the Responsiveness of Anergic CD4+ T Cells Blood. 118: 520-520. DOI: 10.1182/Blood.V118.21.520.520  0.503
2011 Cheng F, Wang Z, Wang H, Woan KV, Sahakian E, Klotz JR, Wang L, Han R, Merino O, Deng S, Vazquez L, Gill AS, Marante D, Powers J, Hancock WW, ... ... Sotomayor EM, et al. Epigenetic Modulation of STAT3 by Histone Deacetylase 6 (HDAC6) Regulates IL-10 Gene Expression and Immune Tolerance Mediated by Antigen-Presenting Cells (APCs) Blood. 118: 519-519. DOI: 10.1182/Blood.V118.21.519.519  0.427
2011 Patel JR, Ho VQ, Teichman ML, Sokol L, Bello CM, Cultrera JL, Sotomayor EM, Wetzstein GA. Rapid Infusion Rituximab in Maintenance Therapy: Is It Feasible? Blood. 118: 4973-4973. DOI: 10.1182/Blood.V118.21.4973.4973  0.308
2011 Chavez JC, Zhang L, Sagatys EM, Sokol L, Moscinski L, Sotomayor EM, Shah BD. Lymphomatoid Granulomatosis: A Clinicopathologic Study of a Series of Cases in a Single Institution Blood. 118: 4960-4960. DOI: 10.1182/Blood.V118.21.4960.4960  0.312
2011 Deaver D, Zuckerman KS, Bello CM, Sotomayor EM, Bruno S, Sokol L. Primary and Secondary Ocular Adnexal Lymphoma: A Single Institutional Experience Blood. 118: 4956-4956. DOI: 10.1182/Blood.V118.21.4956.4956  0.371
2011 Pound HB, Ho VQ, Bello CM, Cultrera JL, Extermann M, Lancet JE, Sotomayor EM, Pinilla-Ibarz J. Bendamustine and Rituximab for the Treatment of Chronic Lymphocytic Leukemia: The Moffitt Cancer Center Experience Blood. 118: 4620-4620. DOI: 10.1182/Blood.V118.21.4620.4620  0.311
2011 Shah BD, Tao J, Sokol L, Chervenick PA, Tomblyn M, Pinilla-Ibarz J, Moscinski L, Antonia S, Sotomayor EM, Dessureault S. Long Term Followup of Bystander Vaccine Therapy in Mantle Cell Lymphoma (MCL), Blood. 118: 3720-3720. DOI: 10.1182/Blood.V118.21.3720.3720  0.365
2011 Woan KV, Wang D, Wang Z, Cheng F, Vazquez L, Woods D, Yu Y, Sahakian E, Wang H, Telles E, Peng L, Wang L, Hancock WW, Blazar BR, Luetteke N, ... ... Sotomayor EM, et al. Histone Deacetylase 11 (HDAC11) Is a Regulatory Checkpoint of T-Cell Function: Implications for T-Cell Adoptive Immunotherapy Blood. 118: 359-359. DOI: 10.1182/Blood.V118.21.359.359  0.478
2011 Kharfan-Dabaja MA, Anasetti C, Luis N, Brand L, Perkins J, Fernandez HF, Ochoa-Bayona JL, Nishihori T, Perez LE, Ayala E, Pinilla-Ibarz J, Sokol L, Pidala J, Locke FL, Sotomayor EM, et al. Phase II Study of a Novel Reduced Toxicity Preparative Regimen for Hematopoietic Cell Allografting Combining Pentostatin (Nipent) and Targeted Doses of Intravenous Busulfan (Busulfex) with or without Rituximab (PB±R) Using a Novel Principle of CD4-Guided Immune Suppression Blood. 118: 3022-3022. DOI: 10.1182/Blood.V118.21.3022.3022  0.327
2011 Sahakian E, Powers J, Rock-Klotz J, Adriani M, Woan KV, Merino O, Gill AS, Deng S, Cheng F, Villagra A, Luetteke N, Seto E, Sotomayor EM, Borrello IM, Pinilla-Ibarz J. A Novel Role of Histone Deacetylase 11 (HDAC11) in Regulation of Myeloid-Derived Suppressor Cell (MDSC) Expansion Blood. 118: 2439-2439. DOI: 10.1182/Blood.V118.21.2439.2439  0.43
2011 Fiskus W, Sharma S, Rao R, Balusu R, Venkannagari S, Hembruff S, Ganguly S, Sotomayor EM, Tao J, Bearss DJ, Bhalla KN. Combined Targeting of Chromatin Modifying Enzymes LSD1, EZH2 and Histone Deacetylases (HDACs) Has Superior Efficacy Against Human Mantle Cell Lymphoma Cells Blood. 118: 2429-2429. DOI: 10.1182/Blood.V118.21.2429.2429  0.411
2011 Powers J, Padron E, Dubovsky J, Berchmans E, Farnum T, Bai F, Sahakian E, Ahmed J, Komrokji RS, Lancet JE, List AF, McNeel DG, Dessureault S, Antonia S, Sotomayor EM, et al. Enhanced Immunological Responses Following K562/GM-CSF/CD40L Vaccine Plus Lenalidomide in High-Risk Myelodysplastic Syndrome Blood. 118: 1725-1725. DOI: 10.1182/Blood.V118.21.1725.1725  0.352
2011 Sahakian E, Shah BD, Powers J, Deng S, Merino O, Gill AS, Rock-Klotz J, Woan KV, Vazquez L, Wang H, Chen-Kiang S, Tao J, Villagra A, Pinilla-Ibarz J, Sotomayor EM. The Opposing Role of Histone Deacetylase 10 (HDAC10) and HDAC11 in Proliferation/Survival of Mantle Cell Lymphoma (MCL) and Chronic Lymphocytic Leukemia (CLL) Blood. 118: 1363-1363. DOI: 10.1182/Blood.V118.21.1363.1363  0.472
2011 Dubovsky JA, Powers JJ, Gao Y, Mariusso LF, Sotomayor EM, Pinilla-Ibarz JA. Abstract 5526: Epigenetic repolarization of T lymphocytes from chronic lymphocytic leukemia patients using 5-aza-2’-deoxycytidine Cancer Research. 71: 5526-5526. DOI: 10.1158/1538-7445.Am2011-5526  0.446
2011 Fiskus WC, Sharma S, Rao R, Balusu R, Tao J, Sotomayor E, Atadja P, Ganguly S, Bearss D, Bhalla KN. Abstract 2016: Combined targeting of epigenetic mechanisms has superior efficacy against human mantle cell lymphoma cells Cancer Research. 71: 2016-2016. DOI: 10.1158/1538-7445.Am2011-2016  0.402
2010 Sotomayor EM. "Skulls and bones" new member: Th17. Blood. 116: 3380-2. PMID 21051562 DOI: 10.1182/Blood-2010-08-300574  0.35
2010 Lwin T, Lin J, Choi YS, Zhang X, Moscinski LC, Wright KL, Sotomayor EM, Dalton WS, Tao J. Follicular dendritic cell-dependent drug resistance of non-Hodgkin lymphoma involves cell adhesion-mediated Bim down-regulation through induction of microRNA-181a. Blood. 116: 5228-36. PMID 20841506 DOI: 10.1182/Blood-2010-03-275925  0.38
2010 Rao R, Nalluri S, Fiskus W, Savoie A, Buckley KM, Ha K, Balusu R, Joshi A, Coothankandaswamy V, Tao J, Sotomayor E, Atadja P, Bhalla KN. Role of CAAT/enhancer binding protein homologous protein in panobinostat-mediated potentiation of bortezomib-induced lethal endoplasmic reticulum stress in mantle cell lymphoma cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 4742-54. PMID 20647473 DOI: 10.1158/1078-0432.Ccr-10-0529  0.398
2010 Desai S, Maurin M, Smith MA, Bolick SC, Dessureault S, Tao J, Sotomayor E, Wright KL. PRDM1 is required for mantle cell lymphoma response to bortezomib. Molecular Cancer Research : McR. 8: 907-18. PMID 20530581 DOI: 10.1158/1541-7786.Mcr-10-0131  0.462
2010 Yuan Z, Villagra A, Peng L, Coppola D, Glozak M, Sotomayor EM, Chen J, Lane WS, Seto E. The ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functions. Molecular and Cellular Biology. 30: 3004-15. PMID 20368352 DOI: 10.1128/Mcb.01023-09  0.311
2010 Brayer J, Cheng F, Wang H, Horna P, Vicente-Suarez I, Pinilla-Ibarz J, Sotomayor EM. Enhanced CD8 T cell cross-presentation by macrophages with targeted disruption of STAT3. Immunology Letters. 131: 126-30. PMID 20346983 DOI: 10.1016/J.Imlet.2010.03.004  0.797
2010 Dubovsky JA, Villagra A, Powers JJ, Wang HW, Pinilla-Ibarz J, Sotomayor EM. Circumventing immune tolerance through epigenetic modification. Current Pharmaceutical Design. 16: 268-76. PMID 20109136 DOI: 10.2174/138161210790170120  0.377
2010 Villagra A, Sotomayor EM, Seto E. Histone deacetylases and the immunological network: Implications in cancer and inflammation Oncogene. 29: 157-173. PMID 19855430 DOI: 10.1038/Onc.2009.334  0.371
2010 Shah BD, Tao J, Sokol L, Chervenick PA, Tomblyn MR, Pinilla-Ibarz J, Moscinski L, Antonia S, Sotomayor EM, Dessureault S. Bystander vaccine therapy in mantle cell lymphoma (MCL): Phase II clinical results. Journal of Clinical Oncology. 28: 2608-2608. DOI: 10.1200/Jco.2010.28.15_Suppl.2608  0.385
2010 Woan K, Cheng F, Wang H, Rock-Klotz J, Wang Z, Yu Y, Seto E, Luetteke N, Yu X, Villagra A, Sotomayor EM. Identification of a Discrete Subpopulation of T-Cells Over-Expressing HDAC11 with a TH17 Phenotype Blood. 116: 588-588. DOI: 10.1182/Blood.V116.21.588.588  0.472
2010 Shah BD, Cultrera JL, Sokol L, Chervenick PA, Bello CM, Sagatys EM, Moscinski LC, Zhang L, Tao J, Sotomayor EM. Evaluation of the Mantle Cell Lymphoma International Prognostic Index (MIPI) as An Indicator of Overall Survival, Progression Free Survival, Survival From Relapse Blood. 116: 5082-5082. DOI: 10.1182/Blood.V116.21.5082.5082  0.331
2010 Dubovsky JA, Powers J, Gao Y, Mariusso LF, Sotomayor EM, Pinilla-Ibarz J. Molecular, Epigenetic, and Phenotypic Repolarization of T Lymphocytes From Chronic Lymphocytic Leukemia Patients Using 5-Aza-2′-Deoxycytidine Blood. 116: 4651-4651. DOI: 10.1182/Blood.V116.21.4651.4651  0.433
2010 Veliz M, Powers J, Zhang L, Santana E, Lancet JE, Komrokji RS, Kharfan-Dabaja M, Tinsley S, Deaver D, Sotomayor EM, Pinilla-Ibarz J. Correlative Analysis of T Cell Subpopulations and CD20 Expression In a Phase II Study of Lenalidomide In Combination with Rituximab In Patients with Relapsed or Refractory CLL/SLL Blood. 116: 4630-4630. DOI: 10.1182/Blood.V116.21.4630.4630  0.43
2010 Beltran B, Morales D, Quinones P, Gallo A, Lopez-Ilasaca M, Miranda R, Sotomayor EM, Castillo JJ. Prevalence and Prognostic Factors of EBV-Positive DLBCL of the Elderly In Peru Blood. 116: 4166-4166. DOI: 10.1182/Blood.V116.21.4166.4166  0.362
2010 Liu J, Zhang L, Ayala E, Field T, Ochoa-Bayona JL, Perez L, Bello CM, Chervenick PA, Bruno S, Sotomayor EM, Sokol L. Plasmablastic Lymphoma: A Series of 16 Cases with the Largest Collection of 9 HIV-Negative Cases Blood. 116: 4162-4162. DOI: 10.1182/Blood.V116.21.4162.4162  0.35
2010 Lin J, Lwin T, Tam W, Zhao J, Crespo L, Choi YS, Zhang X, Tannenbaum V, Sotomayor EM, Moscinski LC, Dalton WS, Wright K, Tao J. Microenvironment-Mediated Regulation of Micrornas In B-Lymphocytes as a Novel Mechanism for Terminal B-Cell Differentiation and Lymphomagenesis. Blood. 116: 3853-3853. DOI: 10.1182/Blood.V116.21.3853.3853  0.333
2010 Zhang X, Chen X, Lin J, Lwin T, Ely SA, Chen-Kiang S, Dalton WS, Seto E, Wright K, Sotomayor EM, Tao J. Myc Represses miR15a/Mir-16-1 Expression through Recruitment of HDAC3 In Mantle Cell Lymphoma Blood. 116: 3121-3121. DOI: 10.1182/Blood.V116.21.3121.3121  0.325
2010 Lwin T, Lin J, Choi YS, Zhang X, Moscinski L, Wright K, Sotomayor EM, Dalton W, Tao J. Microenvironment-Mediated Bim Down-Regulation through Induction of Microrna-181a Protects Cells From Apoptosis In Mantle-Cell and Other Non-Hodgkin B-Cell Lymphomas Blood. 116: 3118-3118. DOI: 10.1182/Blood.V116.21.3118.3118  0.384
2010 Beltran B, Salas R, Chunga A, Sotomayor EM, Castillo JJ. Quantification of EBV DNA In Whole Blood In Newly Diagnosed Patients with Diffuse Large B-Cell Lymphoma Blood. 116: 3102-3102. DOI: 10.1182/Blood.V116.21.3102.3102  0.344
2010 Padron E, Komrokji RS, Lancet JE, List AF, Dessureault S, Antonia S, Ahmed J, Patel S, Powers J, Bai F, Sotomayor EM, Epling-Burnette P, Pinilla-Ibarz J. A Phase I Pilot Study of Bystander Vaccine and Lenalidomide Immune Augmentation In Patients with Myelodysplastic Syndrome (MDS) Blood. 116: 2925-2925. DOI: 10.1182/Blood.V116.21.2925.2925  0.386
2010 Cultrera JL, Liu J, Liboy I, Bello CM, Sokol L, Sotomayor EM, Santana E, Cabanillas F. A Phase II Study of Gemcitabine, Rituximab, and Oxaliplatin In Combination for Relapsed/Refractory Non-Hodgkin's Lymphomas Blood. 116: 2879-2879. DOI: 10.1182/Blood.V116.21.2879.2879  0.393
2010 Rao R, Fiskus W, Balusu R, Ma H, Bradner J, Tao J, Sotomayor EM, Bhalla KN. Treatment with Histone Deacetylase 6-Specific Inhibitor WT-161 Disrupts hsp90 Function, Abrogates Aggresome Formation and Sensitizes Human Mantle Cell Lymphoma Cells to Lethal ER Stress Induced by Proteasome Inhibitor Carfilzomib Blood. 116: 2856-2856. DOI: 10.1182/Blood.V116.21.2856.2856  0.39
2010 Shah BD, Villagra A, Merino O, Rock-Klotz J, Woan K, Seto E, Martin P, Leonard JP, Chen-Kiang S, Tao J, Sotomayor EM. HDAC Profiling In Mantle Cell Lymphoma Unveils HDAC11 and HDAC10 as Potential Molecular Targets Blood. 116: 2506-2506. DOI: 10.1182/Blood.V116.21.2506.2506  0.453
2010 Fiskus W, Rao R, Balusu R, Tao J, Sotomayor EM, Atadja P, Bhalla KN. Efficacy of Combined Epigenetic Targeting of Histone Methyltransferase EZH2 and Histone deacetylases Against Human Mantle Cell Lymphoma Cells Blood. 116: 2488-2488. DOI: 10.1182/Blood.V116.21.2488.2488  0.389
2010 Cheng F, Wang H, Woan K, Rock-Klotz J, Wang Z, Merino O, Gill A, Marante D, Vazquez L, Seto E, Pinilla-Ibarz J, Sotomayor EM, Villagra A. Targeting Histone Deacetylase 6 (HDAC6) as a Novel Approach to Overcome T-Cell Anergy. Blood. 116: 1483-1483. DOI: 10.1182/Blood.V116.21.1483.1483  0.469
2010 Wang D, Cheng F, Yu Y, Semple K, Peng L, Telles E, Luetteke N, Seto E, Anasetti C, Sotomayor EM, Yu X. HDAC11 Inhibits T-Cell Response to Alloantigens and Reduces Gvhd In Mice. Blood. 116: 1466-1466. DOI: 10.1182/Blood.V116.21.1466.1466  0.461
2010 Dubovsky JA, Powers JJ, Gao Y, Pinilla-Ibarz JA, Sotomayor EM. Abstract 4771: Molecular, epigenetic, and phenotypic repolarization of human T lymphocytes using 5-aza-2′-deoxycytidine increases CD8 responsiveness and induces Th1 polarity Cancer Research. 70: 4771-4771. DOI: 10.1158/1538-7445.Am10-4771  0.431
2009 Schuster SJ, Neelapu SS, Gause BL, Muggia FM, Gockerman JP, Sotomayor EM, Winter JN, Flowers CR, Stergiou AM, Kwak LW. Idiotype vaccine therapy (BiovaxID) in follicular lymphoma in first complete remission: Phase III clinical trial results. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 2. PMID 27937596 DOI: 10.1200/Jco.2009.27.15_Suppl.2  0.333
2009 Vicente-Suarez I, Brayer J, Villagra A, Cheng F, Sotomayor EM. TLR5 ligation by flagellin converts tolerogenic dendritic cells into activating antigen-presenting cells that preferentially induce T-helper 1 responses. Immunology Letters. 125: 114-8. PMID 19555720 DOI: 10.1016/J.Imlet.2009.06.007  0.791
2009 Rao R, Lee P, Fiskus W, Yang Y, Joshi R, Wang Y, Buckley K, Balusu R, Chen J, Koul S, Joshi A, Upadhyay S, Tao J, Sotomayor E, Bhalla KN. Co-treatment with heat shock protein 90 inhibitor 17-dimethylaminoethylamino-17-demethoxygeldanamycin (DMAG) and vorinostat: a highly active combination against human mantle cell lymphoma (MCL) cells. Cancer Biology & Therapy. 8: 1273-80. PMID 19440035 DOI: 10.4161/Cbt.8.13.8726  0.374
2009 Dubovsky JA, McNeel DG, Powers JJ, Gordon J, Sotomayor EM, Pinilla-Ibarz JA. Treatment of chronic lymphocytic leukemia with a hypomethylating agent induces expression of NXF2, an immunogenic cancer testis antigen. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 3406-15. PMID 19401350 DOI: 10.1182/Blood.V112.11.4207.4207  0.41
2009 Corzo CA, Cotter MJ, Cheng P, Cheng F, Kusmartsev S, Sotomayor E, Padhya T, McCaffrey TV, McCaffrey JC, Gabrilovich DI. Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 5693-701. PMID 19380816 DOI: 10.4049/Jimmunol.0900092  0.425
2009 Villagra A, Cheng F, Wang HW, Suarez I, Glozak M, Maurin M, Nguyen D, Wright KL, Atadja PW, Bhalla K, Pinilla-Ibarz J, Seto E, Sotomayor EM. The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance. Nature Immunology. 10: 92-100. PMID 19011628 DOI: 10.1038/Ni.1673  0.486
2009 Lwin T, Crespo LA, Wu A, Dessureault S, Shu HB, Moscinski LC, Sotomayor E, Dalton WS, Tao J. Lymphoma cell adhesion-induced expression of B cell-activating factor of the TNF family in bone marrow stromal cells protects non-Hodgkin's B lymphoma cells from apoptosis. Leukemia. 23: 170-7. PMID 18843286 DOI: 10.1038/Leu.2008.266  0.431
2009 Shah BD, Sagatys E, Zhang L, Moscinski LC, Sotomayor EM. Brisk Lymphocytosis with Aberrant Expression of CD5 in the Leukemic Phase of Follicular Lymphoma. Blood. 114: 5033-5033. DOI: 10.1182/Blood.V114.22.5033.5033  0.391
2009 Beltran B, Quinones P, Morales D, Capellino A, Miranda R, Bueso-Ramos CE, Sotomayor EM, Castillo J. Clinical Outcome and Survival of EBV-Positive Diffuse Large B-Cell Lymphoma. Blood. 114: 5005-5005. DOI: 10.1182/Blood.V114.22.5005.5005  0.362
2009 Dubovsky JA, Berchmans E, Powers JJ, Hui-Yi L, Gao Y, Sotomayor E, Pinilla J. Molecular Profiling of Cancer Testis Antigens in Chronic Lymphocytic Leukemia. Blood. 114: 4701-4701. DOI: 10.1182/Blood.V114.22.4701.4701  0.368
2009 Lin J, Lwin T, Zhao J, Zhao J, Crespo L, Sotomayor EM, Moscinski LC, Dalton WS, Wright K, Tao J. Follicular Dendritic Cell (FDC)-Induced Microrna-Mediated up-Regulation of PRDM1 and Down-Regulation of BCL6 in Germinal Center B Lymphocytes: A Potential Mechanism for B-Cell Differentiation. Blood. 114: 4588-4588. DOI: 10.1182/Blood.V114.22.4588.4588  0.402
2009 Shah BD, Veliz M, Santana R, Lancet JE, Powers JJ, Dubovsky JA, Tinsley S, Deaver D, Sotomayor EM, Pinilla J. Hypercalcemia Following Treatment with Lenalidomide in Chronic Lymphocytic Leukemia (CLL). Blood. 114: 4413-4413. DOI: 10.1182/Blood.V114.22.4413.4413  0.335
2009 Veliz M, Moscinski LC, Zhang L, Sotomayor EM, Pinilla-Ibarz J. Lymphoplasmacytic Differentiation Associated with Lenalidomide Therapy in Patients with Chronic Lymphocytic Leukemia. Blood. 114: 4412-4412. DOI: 10.1182/Blood.V114.22.4412.4412  0.429
2009 Veliz M, Santana R, Lancet JE, Komrokji RS, Kharfan-Dabaja MA, Powers JJ, Dubovsky JA, Tinsley S, Deaver D, Sotomayor EM, Pinilla-Ibarz J. Phase II Study of Lenalidomide in Combination with Rituximab for Patients with CD5+/CD20+ Hematologic Malignancies Who Relapse or Progress After Rituximab. Interim Analysis. Blood. 114: 2376-2376. DOI: 10.1182/Blood.V114.22.2376.2376  0.374
2009 Powers JJ, Dubovsky JA, Zhang L, Moscinski LC, Epling-Burnette P, Sotomayor EM, Pinilla J. Molecular and Functional Analysis of Large Granular Lymphocyte Expansions in Chronic Myelogenous Leukemia Patients Undergoing Tyrosine Kinase Inhibitor Therapy. Blood. 114: 2204-2204. DOI: 10.1182/Blood.V114.22.2204.2204  0.434
2009 Lin J, Zhao J, Lwin T, Luis C, Guan F, Dessureault S, Moscinski LC, Dalton WS, Sotomayor EM, Cheng J, Tao J. MiR-29 MicroRNAs Regulate IGF-1R Expression and Contribute Mantle Cell Lymphoma Growth and Survival. Blood. 114: 1957-1957. DOI: 10.1182/Blood.V114.22.1957.1957  0.314
2009 Beltran B, Morales D, Quinones P, Desposorio C, Sotomayor E, Castillo J. Lymphopenia Predicts Survival in Peripheral T-Cell Lymphoma, Unspecified. Blood. 114: 1930-1930. DOI: 10.1182/Blood.V114.22.1930.1930  0.377
2009 Cheng F, Wang H, Luetteke N, Pinilla J, Kozikowski A, Seto E, Villagra Av, Sotomayor E. A Novel Role for Histone Deacetylase 6 (HDAC6) in the Regulation of IL-10 and Immune Tolerance Mediated by Antigen-Presenting Cells (APCs). Blood. 114: 1360-1360. DOI: 10.1182/Blood.V114.22.1360.1360  0.474
2009 Villagra A, Cheng F, Wang H, Suarez I, Glozak M, Maurin M, Nguyen D, Wright KL, Atadja PW, Bhalla K, Pinilla-Ibarz J, Seto E, Sotomayor EM. Erratum: The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance Nature Immunology. 10: 665-665. DOI: 10.1038/Ni0609-665C  0.335
2008 Wang H, Cheng F, Wright K, Tao J, Smith M, Pinilla J, Dessureault S, Sebti S, Sotomayor E. Targeting STAT3 Signaling to Augment the Immunogenicity of B-Cell Lymphomas Blood. 112: 708-708. DOI: 10.1182/blood.v112.11.708.708  0.423
2008 Villagra Av, Maurin Mm, Cheng F, Wang H, Dessureault S, Seto E, Tao J, Wright K, Pinilla J, Sotomayor EM. Histone Deacetylase 11 (HDAC11) as a Novel Molecular Target in Mantle Cell Lymphoma Blood. 112: 4494-4494. DOI: 10.1182/Blood.V112.11.4494.4494  0.471
2008 Kharfan-Dabaja MA, Tate C, Perkins J, Field T, Fernandez HF, Alsina M, Ayala E, Raychaudhuri J, Perez L, Ochoa-Bayona JL, Brand L, Pinilla-Ibarz J, Sotomayor E, Sullivan D, Anasetti C. Administration of Rituximab 375 Mg/m2 on Days +1 and +8 after Allogeneic Hematopoietic Stem Cell Transplantation (allo-HCT) Regimens for Patients with Advanced CD20+ Lymphoid Malignancies Blood. 112: 4323-4323. DOI: 10.1182/Blood.V112.11.4323.4323  0.313
2008 Dubovsky JA, Powers JJ, Sotomayor EM, Pinilla J. Changes in Immunogenicity of Chronic Lymphocytic Leukemia Cells Mediated by Epigenetic Modifiers Blood. 112: 4202-4202. DOI: 10.1182/Blood.V112.11.4202.4202  0.437
2008 Fiskus W, Wang Y, Jillella A, Johnston P, Joshi R, Rao R, Sotomayor E, Tao J, Atadja P, Marqez V, Bhalla KN. Combined Epigenetic Therapy with the Novel Histone Methyl Transferase EZH2 Inhibitor 3-Deazaneplanocin and Histone Deacetylase Inhibitor Panobinostat Exerts Synergistic Activity against Human Mantle Cell Lymphoma Cells Blood. 112: 3622-3622. DOI: 10.1182/Blood.V112.11.3622.3622  0.404
2008 Vicente-Suarez I, Villagra A, Sotomayor EM. Signaling pathways in antigen-presenting cells involved in the induction of antigen-specific T-cell tolerance Tumor Induced Immune Suppression: Mechanisms and Therapeutic Reversal. 197-218. DOI: 10.1007/978-0-387-69118-3_9  0.785
2007 Bello C, Sotomayor EM. Monoclonal antibodies for B-cell lymphomas: rituximab and beyond. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 233-42. PMID 18024635 DOI: 10.1182/Asheducation-2007.1.233  0.352
2007 Vicente-Suarez I, Takahashi Y, Cheng F, Horna P, Wang HW, Wang HG, Sotomayor EM. Identification of a novel negative role of flagellin in regulating IL-10 production. European Journal of Immunology. 37: 3164-75. PMID 17948265 DOI: 10.1002/Eji.200737306  0.77
2007 Villagra A, Ulloa N, Zhang X, Yuan Z, Sotomayor E, Seto E. Histone deacetylase 3 down-regulates cholesterol synthesis through repression of lanosterol synthase gene expression Journal of Biological Chemistry. 282: 35457-35470. PMID 17925399 DOI: 10.1074/Jbc.M701719200  0.322
2007 Lwin T, Hazlehurst LA, Dessureault S, Lai R, Bai W, Sotomayor E, Moscinski LC, Dalton WS, Tao J. Cell adhesion induces p27Kip1-associated cell-cycle arrest through down-regulation of the SCFSkp2 ubiquitin ligase pathway in mantle-cell and other non-Hodgkin B-cell lymphomas. Blood. 110: 1631-8. PMID 17502456 DOI: 10.1182/Blood-2006-11-060350  0.416
2007 Lwin T, Hazlehurst LA, Li Z, Dessureault S, Sotomayor E, Moscinski LC, Dalton WS, Tao J. Bone marrow stromal cells prevent apoptosis of lymphoma cells by upregulation of anti-apoptotic proteins associated with activation of NF-kappaB (RelB/p52) in non-Hodgkin's lymphoma cells. Leukemia. 21: 1521-31. PMID 17476277 DOI: 10.1038/Sj.Leu.2404723  0.405
2007 Horna P, Sotomayor EM. Cellular and molecular mechanisms of tumor-induced T-cell tolerance. Current Cancer Drug Targets. 7: 41-53. PMID 17305477 DOI: 10.2174/156800907780006940  0.451
2007 Rabinovich GA, Gabrilovich D, Sotomayor EM. Immunosuppressive strategies that are mediated by tumor cells. Annual Review of Immunology. 25: 267-96. PMID 17134371 DOI: 10.1146/Annurev.Immunol.25.022106.141609  0.403
2007 Dessureault S, Noyes D, Lee D, Dunn M, Janssen W, Cantor A, Sotomayor E, Messina J, Antonia SJ. A phase-I trial using a universal GM-CSF-producing and CD40L-expressing bystander cell line (GM.CD40L) in the formulation of autologous tumor cell-based vaccines for cancer patients with stage IV disease. Annals of Surgical Oncology. 14: 869-84. PMID 17103257 DOI: 10.1245/S10434-006-9196-4  0.406
2007 Dessureault S, Noyes D, Tao J, Moscinski L, Schell M, Antonia SJ, Sotomayor EM. Bystander-Based Immunotherapy for Patients with Mantle Cell Lymphoma (MCL): Proof of Principle. Blood. 110: 4483-4483. DOI: 10.1182/Blood.V110.11.4483.4483  0.369
2007 Cheng F, Horna P, Wang H, Suarez I, Chen X, Wei S, Sotomayor EM. Critical Role of Neutrophils in Determining Antigen-Specific CD4+ T-Cell Tolerance In Vivo. Blood. 110: 3294-3294. DOI: 10.1182/Blood.V110.11.3294.3294  0.444
2007 Wang H, Cheng F, Noyes D, Wright K, Mohapatra S, Tao J, Schell M, Sebti S, Smith M, Bhalla K, Pinilla J, Dessureault S, Celis D, Sotomayor EM, Sotomayor IbEM. Enhancement of the Antigen-Presenting Cell Function of Mantle Cell Lymphomas (MCL) by Novel Molecularly Based Immunotherapeutic Strategies. Blood. 110: 2315-2315. DOI: 10.1182/Blood.V110.11.2315.2315  0.522
2007 Vicente-Suarez I, Sotomayor EM. Ligation of TLR5 by Flagellin Converts Tolerogenic Dendritic Cells into Activating Dendritic Cells through Inhibition of IL-10 Production. Blood. 110: 2314-2314. DOI: 10.1182/Blood.V110.11.2314.2314  0.783
2007 Sagatys E, Moscinski L, Dessureault S, Sotomayor E, Cualing H. Analysis of T-Cell Subpopulations in the Lymph Nodes of Patients with Mantle Cell Lymphoma. Blood. 110: 1580-1580. DOI: 10.1182/Blood.V110.11.1580.1580  0.339
2007 Mohapatra S, Chu B, Zhao X, Tao J, Sotomayor E, Pledger WJ. Combined Inhibition of CDK and PI3K/Akt Pathways Induces Apoptosis of Mantle Cell Lymphoma. Blood. 110: 1384-1384. DOI: 10.1182/Blood.V110.11.1384.1384  0.404
2007 Rao R, Fiskus W, Joshi R, Chen J, Fernandez P, Wang Y, Lee P, Jillella A, Tao J, Atadja P, Sotomayor E, Bhalla K. Targeting Histone Deacetylases and Unfolded Protein Mediated Endoplasmic Reticulum (ER) Stress as a Strategy Against Human Mantle Cell Lymphoma. Blood. 110: 1378-1378. DOI: 10.1182/Blood.V110.11.1378.1378  0.379
2007 Wang H, Cheng F, Nguyen D, Suarez I, Wright K, Atadja A, Seto E, Bhalla K, Villagra A, Sotomayor E. A Novel Role of Histone Deacetylase 11 (HDAC11) in the Regulation of IL-10 Production and Immune Tolerance Mediated by Antigen-Presenting Cells. Blood. 110: 1330-1330. DOI: 10.1182/Blood.V110.11.1330.1330  0.459
2006 Horna P, Cuenca A, Cheng F, Brayer J, Wang HW, Borrello I, Levitsky H, Sotomayor EM. In vivo disruption of tolerogenic cross-presentation mechanisms uncovers an effective T-cell activation by B-cell lymphomas leading to antitumor immunity. Blood. 107: 2871-8. PMID 16339406 DOI: 10.1182/Blood-2005-07-3014  0.458
2005 Wang H, Cheng F, Cuenca A, Horna P, Zheng Z, Bhalla K, Sotomayor EM. Imatinib mesylate (STI-571) enhances antigen-presenting cell function and overcomes tumor-induced CD4+ T-cell tolerance. Blood. 105: 1135-43. PMID 15454486 DOI: 10.1182/Blood-2004-01-0027  0.457
2005 Horna P, Chavan R, Brayer J, Suarez I, Sotomayor EM. Age-Related Induction of CD4+ T-Cell Unresponsiveness Is Reversible and Dependant of the Host’s Environment. Blood. 106: 3925-3925. DOI: 10.1182/Blood.V106.11.3925.3925  0.448
2005 Hatter A, Bali P, Balasis M, Fiskus W, Boyapalle S, Kumaraswamy S, Rocha K, Pranpat M, Hannah A, Sotomayor E, Richon V, Bhalla K. Co-Treatment with the hsp90 Inhibitor 17-Dimethylaminoethylamino-17-Demethoxygeldanamycin (DMAG) and Histone Deacetylase Inhibitor (HDI) Vorinostat (Suberoylanilide Hydroxamic Acid, SAHA): A Highly Active Combination Against Human Mantle Cell Lymphoma (MCL) Cells. Blood. 106: 2418-2418. DOI: 10.1182/Blood.V106.11.2418.2418  0.366
2005 Wang H, Cheng F, Horna P, Suarez I, Wu J, Atadja A, Seto E, Wright K, Bhalla K, Sotomayor E. Treatment of Antigen-Presenting Cells with Histone Deacetylase Inhibitors Represents a Novel Strategy To Overcome CD4+ T-Cell Tolerance: Divergent Effects on the IL10 and IL-12 Promoter. Blood. 106: 2392-2392. DOI: 10.1182/Blood.V106.11.2392.2392  0.418
2005 Wang H, Naing A, Cheng F, Horna P, Suarez I, Brayer J, List AF, Sotomayor EM. The Immunomodulatory Drug Lenalidomide (CC5013; Revlimid), Enhances Antigen-Presenting Cell’s Function Leading to Effective Priming of CD4+ T-Lymphocytes. Blood. 106: 2391-2391. DOI: 10.1182/Blood.V106.11.2391.2391  0.503
2005 Cheng F, Wang H, Suarez A, Horna P, Sebti S, Sotomayor EM. Cucurbitacins, a Family of Natural Compounds That Effectively Disrupt Stat3 Signaling in Antigen-Presenting Cells (APCs) Are Promising Agents To Overcome Tumor-Induced CD4+ T-Cell Tolerance. Blood. 106: 1485-1485. DOI: 10.1182/Blood.V106.11.1485.1485  0.506
2004 Cheng F, Gabrilovich D, Sotomayor EM. Immune tolerance in breast cancer. Breast Disease. 20: 93-103. PMID 15687711 DOI: 10.3233/Bd-2004-20111  0.336
2004 Ghansah T, Paraiso KH, Highfill S, Desponts C, May S, McIntosh JK, Wang JW, Ninos J, Brayer J, Cheng F, Sotomayor E, Kerr WG. Expansion of myeloid suppressor cells in SHIP-deficient mice represses allogeneic T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 173: 7324-30. PMID 15585856 DOI: 10.4049/Jimmunol.173.12.7324  0.434
2004 Rodriguez PC, Quiceno DG, Zabaleta J, Ortiz B, Zea AH, Piazuelo MB, Delgado A, Correa P, Brayer J, Sotomayor EM, Antonia S, Ochoa JB, Ochoa AC. Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses. Cancer Research. 64: 5839-49. PMID 15313928 DOI: 10.1158/0008-5472.Can-04-0465  0.438
2004 Brayer J, Cheng F, Horna P, Suarez I, Wang H, Sotomayor EM. Analysis of the Fate and Function of Antigen-Specific CD8 T Cells during B Cell Lymphoma Progression. Blood. 104: 80-80. DOI: 10.1182/Blood.V104.11.80.80  0.456
2004 Horna P, Cheng F, Jove R, Mora L, Sotomayor EM. In Vivo Visualization of Stat3 Activation in Myeloid Cells during Inflammation and Tumor Growth. Blood. 104: 3434-3434. DOI: 10.1182/Blood.V104.11.3434.3434  0.471
2004 Cheng F, Wang H, Cuenca AG, Horna P, Suarez L, Brayer J, Turkson J, Jove R, Sotomayor EM. Disruption of STAT3 Signaling in Antigen Presenting Cells Represents a Novel Strategy To Overcome Tumor-Induced Antigen-Specific CD4+ T-Cell Tolerance. Blood. 104: 109-109. DOI: 10.1182/Blood.V104.11.109.109  0.467
2003 Cheng F, Wang HW, Cuenca A, Huang M, Ghansah T, Brayer J, Kerr WG, Takeda K, Akira S, Schoenberger SP, Yu H, Jove R, Sotomayor EM. A critical role for Stat3 signaling in immune tolerance. Immunity. 19: 425-36. PMID 14499117 DOI: 10.1016/S1074-7613(03)00232-2  0.451
2002 Sotomayor MG, Yu H, Antonia S, Sotomayor EM, Pardoll DM. Advances in gene therapy for malignant melanoma. Cancer Control : Journal of the Moffitt Cancer Center. 9: 39-48. PMID 11907465 DOI: 10.1177/107327480200900106  0.302
2001 Sotomayor EM, Borrello I, Rattis FM, Cuenca AG, Abrams J, Staveley-O'Carroll K, Levitsky HI. Cross-presentation of tumor antigens by bone marrow-derived antigen-presenting cells is the dominant mechanism in the induction of T-cell tolerance during B-cell lymphoma progression Blood. 98: 1070-1077. PMID 11493453 DOI: 10.1182/Blood.V98.4.1070  0.453
2001 Gabrilovich DI, Velders MP, Sotomayor EM, Kast WM. Mechanism of immune dysfunction in cancer mediated by immature Gr-1+ myeloid cells Journal of Immunology. 166: 5398-5406. PMID 11313376 DOI: 10.4049/Jimmunol.166.9.5398  0.47
2000 Borrello I, Sotomayor EM, Rattis FM, Cooke SK, Gu L, Levitsky HI. Sustaining the graft-versus-tumor effect through posttransplant immunization with granulocyte-macrophage colony-stimulating factor (GM-CSF)- producing tumor vaccines Blood. 95: 3011-3019. PMID 10807763 DOI: 10.1182/Blood.V95.10.3011.010K15_3011_3019  0.366
2000 Lu Z, Yuan L, Zhou X, Sotomayor E, Levitsky HI, Pardoll DM. CD40-independent pathways of T cell help for priming of CD8(+) cytotoxic T lymphocytes. The Journal of Experimental Medicine. 191: 541-50. PMID 10662799 DOI: 10.1084/Jem.191.3.541  0.366
1999 Sotomayor EM, Borrello I, Tubb E, Rattis FM, Bien H, Lu Z, Fein S, Schoenberger S, Levitsky HI. Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40. Nature Medicine. 5: 780-7. PMID 10395323 DOI: 10.1038/10503  0.432
1996 Sotomayor EM, Borrello I, Levitsky HI. Tolerance and cancer: A critical issue in tumor immunology Critical Reviews in Oncogenesis. 7: 433-456. PMID 9467666 DOI: 10.1615/Critrevoncog.V7.I5-6.30  0.41
1995 Sotomayor EM, DiNapoli MR, Calderon C, Colsky A, Fu YX, Lopez DM. Decreased macrophage-mediated cytotoxicity in mammary-tumor-bearing mice is related to alteration of nitric-oxide production and/or release International Journal of Cancer. 60: 660-667. PMID 7860141 DOI: 10.1002/Ijc.2910600516  0.316
1994 César Calderón H, Huang ZH, Gage DA, Sotomayor EM, Lopez DM. Isolation of a nitric oxide inhibitor from mammary tumor cells and its characterization as phosphatidyl serine Journal of Experimental Medicine. 180: 945-958. PMID 8064242 DOI: 10.1084/Jem.180.3.945  0.341
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