William P. Halford - Publications

Affiliations: 
Molecular Biology Microbiology and Biochemistry Southern Illinois University at Carbondale, Carbondale, IL 
Area:
Virology Biology, Molecular Biology, Cell Biology

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Royer DJ, Carr MM, Gurung HR, Halford WP, Carr DJJ. The Neonatal Fc Receptor and Complement Fixation Facilitate Prophylactic Vaccine-Mediated Humoral Protection against Viral Infection in the Ocular Mucosa. Journal of Immunology (Baltimore, Md. : 1950). PMID 28760885 DOI: 10.4049/Jimmunol.1700316  0.391
2017 Royer DJ, Carr MM, Chucair-Elliott AJ, Halford WP, Carr DJ. Impact of type 1 interferon on the safety and immunogenicity of an experimental live-attenuated herpes simplex virus type 1 vaccine in mice. Journal of Virology. PMID 28122977 DOI: 10.1128/Jvi.02342-16  0.46
2016 Royer DJ, Gurung HR, Jinkins JK, Geltz JJ, Wu JL, Halford WP, Carr DJ. A Highly Efficacious HSV-1 Vaccine Blocks Viral Pathogenesis and Prevents Corneal Immunopathology Via Humoral Immunity. Journal of Virology. PMID 27030264 DOI: 10.1128/Jvi.00517-16  0.444
2015 Halford WP, Geltz J, Messer RJ, Hasenkrug KJ. Antibodies Are Required for Complete Vaccine-Induced Protection against Herpes Simplex Virus 2. Plos One. 10: e0145228. PMID 26670699 DOI: 10.1371/Journal.Pone.0145228  0.449
2015 Ariotti S, Beltman JB, Borsje R, Hoekstra ME, Halford WP, Haanen JB, de Boer RJ, Schumacher TN. Subtle CXCR3-Dependent Chemotaxis of CTLs within Infected Tissue Allows Efficient Target Localization. Journal of Immunology (Baltimore, Md. : 1950). 195: 5285-95. PMID 26525288 DOI: 10.4049/Jimmunol.1500853  0.387
2015 Gershburg S, Geltz J, Peterson KE, Halford WP, Gershburg E. The UL13 and US3 Protein Kinases of Herpes Simplex Virus 1 Cooperate to Promote the Assembly and Release of Mature, Infectious Virions. Plos One. 10: e0131420. PMID 26115119 DOI: 10.1371/Journal.Pone.0131420  0.479
2015 Chambers CB, Halford WP, Geltz J, Villamizar O, Gross J, Embalabala A, Gershburg E, Wilber A. A system for creating stable cell lines that express a gene of interest from a bidirectional and regulatable herpes simplex virus type 1 promoter. Plos One. 10: e0122253. PMID 25823013 DOI: 10.1371/Journal.Pone.0122253  0.374
2015 Geltz JJ, Gershburg E, Halford WP. Herpes simplex virus 2 (HSV-2) infected cell proteins are among the most dominant antigens of a live-attenuated HSV-2 vaccine. Plos One. 10: e0116091. PMID 25658852 DOI: 10.1371/Journal.Pone.0116091  0.486
2014 Halford WP. Antigenic breadth: a missing ingredient in HSV-2 subunit vaccines? Expert Review of Vaccines. 13: 691-710. PMID 24837838 DOI: 10.1586/14760584.2014.910121  0.417
2014 Workenhe ST, Simmons G, Pol JG, Lichty BD, Halford WP, Mossman KL. Immunogenic HSV-mediated oncolysis shapes the antitumor immune response and contributes to therapeutic efficacy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 123-31. PMID 24343053 DOI: 10.1038/Mt.2013.238  0.499
2013 Halford WP, Geltz J, Gershburg E. Pan-HSV-2 IgG antibody in vaccinated mice and guinea pigs correlates with protection against herpes simplex virus 2. Plos One. 8: e65523. PMID 23755244 DOI: 10.1371/Journal.Pone.0065523  0.466
2013 Nixon B, Stefanidou M, Mesquita PM, Fakioglu E, Segarra T, Rohan L, Halford W, Palmer KE, Herold BC. Griffithsin protects mice from genital herpes by preventing cell-to-cell spread. Journal of Virology. 87: 6257-69. PMID 23536670 DOI: 10.1128/Jvi.00012-13  0.413
2012 Hill JM, Nolan NM, McFerrin HE, Clement C, Foster TP, Halford WP, Kousoulas KG, Lukiw WJ, Thompson HW, Stern EM, Bhattacharjee PS. HSV-1 latent rabbits shed viral DNA into their saliva. Virology Journal. 9: 221. PMID 23021094 DOI: 10.1186/1743-422X-9-221  0.403
2011 Wuest T, Zheng M, Efstathiou S, Halford WP, Carr DJJ. The herpes simplex virus-1 transactivator infected cell protein-4 drives VEGF-A dependent Neovascularization Plos Pathogens. 7. PMID 21998580 DOI: 10.1371/Journal.Ppat.1002278  0.405
2011 Halford WP, Püschel R, Gershburg E, Wilber A, Gershburg S, Rakowski B. A live-attenuated HSV-2 ICP0 virus elicits 10 to 100 times greater protection against genital herpes than a glycoprotein D subunit vaccine. Plos One. 6: e17748. PMID 21412438 DOI: 10.1371/Journal.Pone.0017748  0.514
2011 Conrady CD, Halford WP, Carr DJ. Loss of the type I interferon pathway increases vulnerability of mice to genital herpes simplex virus 2 infection. Journal of Virology. 85: 1625-33. PMID 21147921 DOI: 10.1128/Jvi.01715-10  0.454
2010 Halford WP, Püschel R, Rakowski B. Herpes simplex virus 2 ICP0 mutant viruses are avirulent and immunogenic: implications for a genital herpes vaccine. Plos One. 5: e12251. PMID 20808928 DOI: 10.1371/Journal.Pone.0012251  0.556
2010 Liu M, Schmidt EE, Halford WP. ICP0 dismantles microtubule networks in herpes simplex virus-infected cells. Plos One. 5: e10975. PMID 20544015 DOI: 10.1371/Journal.Pone.0010975  0.586
2010 Liu M, Rakowski B, Gershburg E, Weisend CM, Lucas O, Schmidt EE, Halford WP. ICP0 antagonizes ICP4-dependent silencing of the herpes simplex virus ICP0 gene. Plos One. 5: e8837. PMID 20098619 DOI: 10.1371/Journal.Pone.0008837  0.582
2009 Imai Y, Apakupakul K, Krause PR, Halford WP, Margolis TP. Investigation of the mechanism by which herpes simplex virus type 1 LAT sequences modulate preferential establishment of latent infection in mouse trigeminal ganglia. Journal of Virology. 83: 7873-82. PMID 19493993 DOI: 10.1128/Jvi.00043-09  0.465
2009 Carr DJ, Austin BA, Halford WP, Stuart PM. Delivery of Interferon-gamma by an adenovirus vector blocks herpes simplex virus Type 1 reactivation in vitro and in vivo independent of RNase L and double-stranded RNA-dependent protein kinase pathways. Journal of Neuroimmunology. 206: 39-43. PMID 19042034 DOI: 10.1016/J.Jneuroim.2008.10.008  0.488
2007 Halford WP. Towards an effective genital herpes vaccine: past lessons and future prospects. Future Virology. 2: 1-6. PMID 23843891 DOI: 10.2217/17460794.2.1.1  0.445
2007 Austin BA, Halford WP, Williams BR, Carr DJ. Oligoadenylate synthetase/protein kinase R pathways and alphabeta TCR+ T cells are required for adenovirus vector: IFN-gamma inhibition of herpes simplex virus-1 in cornea. Journal of Immunology (Baltimore, Md. : 1950). 178: 5166-72. PMID 17404299 DOI: 10.4049/Jimmunol.178.8.5166  0.437
2006 Halford WP, Weisend C, Grace J, Soboleski M, Carr DJ, Balliet JW, Imai Y, Margolis TP, Gebhardt BM. ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency. Virology Journal. 3: 44. PMID 16764725 DOI: 10.1186/1743-422X-3-44  0.512
2006 Austin BA, Halford W, Silverman RH, Williams BR, Carr DJ. OAS and PKR are not required for the antiviral effect of Ad:IFN-gamma against acute HSV-1 in primary trigeminal ganglia cultures. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 26: 220-5. PMID 16704298 DOI: 10.1089/jir.2006.26.220  0.371
2005 Gebhardt BM, Halford WP. Evidence that spontaneous reactivation of herpes virus does not occur in mice. Virology Journal. 2: 67. PMID 16109179 DOI: 10.1186/1743-422X-2-67  0.515
2005 Pierce AT, DeSalvo J, Foster TP, Kosinski A, Weller SK, Halford WP. Beta interferon and gamma interferon synergize to block viral DNA and virion synthesis in herpes simplex virus-infected cells. The Journal of General Virology. 86: 2421-32. PMID 16099899 DOI: 10.1099/Vir.0.80979-0  0.505
2005 Halford WP, Maender JL, Gebhardt BM. Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1. Virology Journal. 2: 56. PMID 16022737 DOI: 10.1186/1743-422X-2-56  0.499
2005 Halford WP, Halford KJ, Pierce AT. Mathematical analysis demonstrates that interferons-beta and -gamma interact in a multiplicative manner to disrupt herpes simplex virus replication. Journal of Theoretical Biology. 234: 439-54. PMID 15784277 DOI: 10.1016/J.Jtbi.2004.12.007  0.422
2005 Al-Khatib K, Williams BR, Silverman RH, Halford W, Carr DJ. Dichotomy between survival and lytic gene expression in RNase L- and PKR-deficient mice transduced with an adenoviral vector expressing murine IFN-beta following ocular HSV-1 infection. Experimental Eye Research. 80: 167-73. PMID 15670795 DOI: 10.1016/J.Exer.2004.08.026  0.486
2004 Halford WP, Balliet JW, Gebhardt BM. Re-evaluating natural resistance to herpes simplex virus type 1. Journal of Virology. 78: 10086-95. PMID 15331741 DOI: 10.1128/Jvi.78.18.10086-10095.2004  0.44
2004 Al-Khatib K, Williams BR, Silverman RH, Halford W, Carr DJ. Distinctive roles for 2',5'-oligoadenylate synthetases and double-stranded RNA-dependent protein kinase R in the in vivo antiviral effect of an adenoviral vector expressing murine IFN-beta. Journal of Immunology (Baltimore, Md. : 1950). 172: 5638-47. PMID 15100308 DOI: 10.4049/jimmunol.172.9.5638  0.407
2003 Al-khatib K, Williams BR, Silverman RH, Halford W, Carr DJ. The murine double-stranded RNA-dependent protein kinase PKR and the murine 2',5'-oligoadenylate synthetase-dependent RNase L are required for IFN-beta-mediated resistance against herpes simplex virus type 1 in primary trigeminal ganglion culture. Virology. 313: 126-35. PMID 12951027 DOI: 10.1016/S0042-6822(03)00298-8  0.456
2002 Al-Khatib K, Williams BR, Silverman RH, Halford WP, Carr DJ. Absence of PKR attenuates the anti-HSV-1 activity of an adenoviral vector expressing murine IFN-beta. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 22: 861-71. PMID 12396725 DOI: 10.1089/107999002760274872  0.461
2002 Sainz B, Halford WP. Alpha/Beta interferon and gamma interferon synergize to inhibit the replication of herpes simplex virus type 1. Journal of Virology. 76: 11541-50. PMID 12388715 DOI: 10.1128/Jvi.76.22.11541-11550.2002  0.466
2002 Härle P, Sainz B, Carr DJ, Halford WP. The immediate-early protein, ICP0, is essential for the resistance of herpes simplex virus to interferon-alpha/beta. Virology. 293: 295-304. PMID 11886249 DOI: 10.1006/Viro.2001.1280  0.473
2001 Halford WP, Kemp CD, Isler JA, Davido DJ, Schaffer PA. ICP0, ICP4, or VP16 expressed from adenovirus vectors induces reactivation of latent herpes simplex virus type 1 in primary cultures of latently infected trigeminal ganglion cells. Journal of Virology. 75: 6143-53. PMID 11390616 DOI: 10.1128/Jvi.75.13.6143-6153.2001  0.411
2001 Halford WP, Schaffer PA. ICP0 is required for efficient reactivation of herpes simplex virus type 1 from neuronal latency Journal of Virology. 75: 3240-3249. PMID 11238850 DOI: 10.1128/Jvi.75.7.3240-3249.2001  0.401
2000 Halford WP, Schaffer PA. Optimized viral dose and transient immunosuppression enable herpes simplex virus ICP0-null mutants to establish wild-type levels of latency in vivo Journal of Virology. 74: 5957-5967. PMID 10846077 DOI: 10.1128/Jvi.74.13.5957-5967.2000  0.392
1998 Hill JM, Wen R, Halford WP. Pathogenesis and Molecular Biology of HSV Latency and Ocular Reactivation in the Rabbit. Methods in Molecular Medicine. 10: 291-315. PMID 21374237 DOI: 10.1385/0-89603-347-3:291  0.344
1998 Carr DJ, Halford WP, Veress LA, Noisakran S, Perng GC, Wechsler SL. The persistent elevated cytokine mRNA levels in trigeminal ganglia of mice latently infected with HSV-1 are not due to the presence of latency associated transcript (LAT) RNAs. Virus Research. 54: 1-8. PMID 9660066 DOI: 10.1016/S0168-1702(98)00007-0  0.442
1998 Halford WP, Veress LA, Gebhardt BM, Carr DJ. Immunization with HSV-1 antigen rapidly protects against HSV-1-induced encephalitis and is IFN-gamma independent. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 18: 151-8. PMID 9555976  0.369
1997 Halford WP, Gebhardt BM, Carr DJJ. Acyclovir blocks cytokine gene expression in trigeminal ganglia latently infected with herpes simplex virus type 1 Virology. 238: 53-63. PMID 9375008 DOI: 10.1006/viro.1997.8806  0.378
1997 Halford WP, Veress LA, Gebhardt BM, Carr DJ. Innate and acquired immunity to herpes simplex virus type 1. Virology. 236: 328-37. PMID 9325240 DOI: 10.1006/viro.1997.8738  0.406
1996 Halford WP, Gebhardt BM, Carr DJJ. Persistent Cytokine Expression in Trigeminal Ganglion Latently Infected with Herpes Simplex Virus Type 1 Journal of Immunology. 157: 3542-3549. PMID 8871654  0.329
1996 Hill JM, Gebhardt BM, Wen R, Bouterie AM, Thompson HW, O'Callaghan RJ, Halford WP, Kaufman HE. Quantitation of herpes simplex virus type 1 DNA and latency-associated transcripts in rabbit trigeminal ganglia demonstrates a stable reservoir of viral nucleic acids during latency. Journal of Virology. 70: 3137-41. PMID 8627793 DOI: 10.1128/Jvi.70.5.3137-3141.1996  0.439
1996 Halford WP, Gebhardt BM, Carr DJJ. Active immunization blocks efficient establishment of latent herpes simplex virus type 1 infection Faseb Journal. 10.  0.414
1995 Halford WP, Carr DJJ. Subversion of intracellular signal transduction by Herpes simplex virus type 1 Advances in Neuroimmunology. 5: 327-334. PMID 8748076 DOI: 10.1016/0960-5428(95)00017-V  0.326
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