| Year |
Citation |
Score |
| 2024 |
Richardson K, Sengupta M, Sujkowski A, Libohova K, Harris AC, Wessells R, Merry DE, Todi SV. A phenotypically robust model of spinal and bulbar muscular atrophy in Drosophila. Journal of Neuroscience Research. 102: e25278. PMID 38284836 DOI: 10.1002/jnr.25278 |
0.505 |
|
| 2023 |
Garcia Castro DR, Mazuk JR, Heine EM, Simpson D, Pinches RS, Lozzi C, Hoffman K, Morrin P, Mathis D, Lebedev MV, Nissley E, Han KH, Farmer T, Merry DE, Tong Q, et al. Increased SIRT3 combined with PARP inhibition rescues motor function of SBMA mice. Iscience. 26: 107375. PMID 37599829 DOI: 10.1016/j.isci.2023.107375 |
0.574 |
|
| 2022 |
Sengupta M, Pluciennik A, Merry DE. The role of ubiquitination in spinal and bulbar muscular atrophy. Frontiers in Molecular Neuroscience. 15: 1020143. PMID 36277484 DOI: 10.3389/fnmol.2022.1020143 |
0.456 |
|
| 2022 |
Molotsky E, Liu Y, Lieberman AP, Merry DE. Neuromuscular junction pathology is correlated with differential motor unit vulnerability in spinal and bulbar muscular atrophy. Acta Neuropathologica Communications. 10: 97. PMID 35791011 DOI: 10.1186/s40478-022-01402-y |
0.341 |
|
| 2020 |
Pluciennik A, Liu Y, Molotsky E, Marsh GB, Ranxhi B, Arnold FJ, St-Cyr S, Davidson BL, Pourshafie N, Lieberman AP, Gu W, Todi SV, Merry DE. Deubiquitinase USP7 contributes to the pathogenicity of spinal and bulbar muscular atrophy. The Journal of Clinical Investigation. PMID 33170804 DOI: 10.1172/JCI134565 |
0.555 |
|
| 2019 |
Arnold FJ, Merry DE. Molecular Mechanisms and Therapeutics for SBMA/Kennedy's Disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 31686397 DOI: 10.1007/s13311-019-00790-9 |
0.399 |
|
| 2019 |
Arnold FJ, Pluciennik A, Merry DE. Impaired Nuclear Export of Polyglutamine-Expanded Androgen Receptor in Spinal and Bulbar Muscular Atrophy. Scientific Reports. 9: 119. PMID 30644418 DOI: 10.1038/s41598-018-36784-4 |
0.524 |
|
| 2017 |
Yersak JM, Montie HL, Chevalier-Larsen ES, Liu Y, Huang L, Rechsteiner M, Merry DE. The 11S Proteasomal Activator REGγ Impacts Polyglutamine-Expanded Androgen Receptor Aggregation and Motor Neuron Viability through Distinct Mechanisms. Frontiers in Molecular Neuroscience. 10: 159. PMID 28596723 DOI: 10.3389/Fnmol.2017.00159 |
0.659 |
|
| 2016 |
Bott LC, Salomons FA, Maric D, Liu Y, Merry D, Fischbeck KH, Dantuma NP. The polyglutamine-expanded androgen receptor responsible for spinal and bulbar muscular atrophy inhibits the APC/C(Cdh1) ubiquitin ligase complex. Scientific Reports. 6: 27703. PMID 27312068 DOI: 10.1038/Srep27703 |
0.569 |
|
| 2015 |
Zboray L, Pluciennik A, Curtis D, Liu Y, Berman-Booty LD, Orr C, Kesler CT, Berger T, Gioeli D, Paschal BM, Merry DE. Preventing the Androgen Receptor N/C Interaction Delays Disease Onset in a Mouse Model of SBMA. Cell Reports. PMID 26673324 DOI: 10.1016/J.Celrep.2015.11.019 |
0.408 |
|
| 2015 |
Berger TR, Montie HL, Jain P, Legleiter J, Merry DE. Identification of novel polyglutamine-expanded aggregation species in spinal and bulbar muscular atrophy. Brain Research. PMID 26453288 DOI: 10.1016/J.Brainres.2015.09.033 |
0.434 |
|
| 2015 |
Heine EM, Berger TR, Pluciennik A, Orr CR, Zboray L, Merry DE. Proteasome-mediated proteolysis of the polyglutamine-expanded androgen receptor is a late event in spinal and bulbar muscular atrophy (SBMA) pathogenesis. The Journal of Biological Chemistry. 290: 12572-84. PMID 25795778 DOI: 10.1074/Jbc.M114.617894 |
0.579 |
|
| 2015 |
Chua JP, Reddy SL, Yu Z, Giorgetti E, Montie HL, Mukherjee S, Higgins J, McEachin RC, Robins DM, Merry DE, Iñiguez-Lluhà JA, Lieberman AP. Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor-mediated disease. The Journal of Clinical Investigation. 125: 831-45. PMID 25607844 DOI: 10.1172/Jci73214 |
0.428 |
|
| 2014 |
Chua JP, Reddy SL, Merry DE, Adachi H, Katsuno M, Sobue G, Robins DM, Lieberman AP. Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy. Human Molecular Genetics. 23: 1376-86. PMID 24150846 DOI: 10.1093/Hmg/Ddt527 |
0.391 |
|
| 2013 |
Cooper LJ, Merry DE. Cell biological approaches to investigate polyglutamine-expanded AR metabolism. Methods in Molecular Biology (Clifton, N.J.). 1017: 241-53. PMID 23719921 DOI: 10.1007/978-1-62703-438-8_18 |
0.559 |
|
| 2013 |
Wang AM, Miyata Y, Klinedinst S, Peng HM, Chua JP, Komiyama T, Li X, Morishima Y, Merry DE, Pratt WB, Osawa Y, Collins CA, Gestwicki JE, Lieberman AP. Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation. Nature Chemical Biology. 9: 112-8. PMID 23222885 DOI: 10.1038/Nchembio.1140 |
0.36 |
|
| 2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Merry DE, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.318 |
|
| 2012 |
Xiao H, Yu Z, Wu Y, Nan J, Merry DE, Sekiguchi JM, Ferguson DO, Lieberman AP, Dressler GR. A polyglutamine expansion disease protein sequesters PTIP to attenuate DNA repair and increase genomic instability. Human Molecular Genetics. 21: 4225-36. PMID 22736030 DOI: 10.1093/Hmg/Dds246 |
0.333 |
|
| 2011 |
Montie HL, Pestell RG, Merry DE. SIRT1 modulates aggregation and toxicity through deacetylation of the androgen receptor in cell models of SBMA. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 17425-36. PMID 22131404 DOI: 10.1523/Jneurosci.3958-11.2011 |
0.579 |
|
| 2010 |
Orr CR, Montie HL, Liu Y, Bolzoni E, Jenkins SC, Wilson EM, Joseph JD, McDonnell DP, Merry DE. An interdomain interaction of the androgen receptor is required for its aggregation and toxicity in spinal and bulbar muscular atrophy. The Journal of Biological Chemistry. 285: 35567-77. PMID 20826791 DOI: 10.1074/Jbc.M110.146845 |
0.496 |
|
| 2009 |
Montie HL, Merry DE. Autophagy and access: understanding the role of androgen receptor subcellular localization in SBMA. Autophagy. 5: 1194-7. PMID 19770590 DOI: 10.4161/Auto.5.8.9726 |
0.591 |
|
| 2009 |
Mojsilovic-Petrovic J, Nedelsky N, Boccitto M, Mano I, Georgiades SN, Zhou W, Liu Y, Neve RL, Taylor JP, Driscoll M, Clardy J, Merry D, Kalb RG. FOXO3a is broadly neuroprotective in vitro and in vivo against insults implicated in motor neuron diseases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8236-47. PMID 19553463 DOI: 10.1523/Jneurosci.1805-09.2009 |
0.507 |
|
| 2009 |
Montie HL, Cho MS, Holder L, Liu Y, Tsvetkov AS, Finkbeiner S, Merry DE. Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy. Human Molecular Genetics. 18: 1937-50. PMID 19279159 DOI: 10.1093/Hmg/Ddp115 |
0.602 |
|
| 2009 |
Schiewer MJ, Morey LM, Burd CJ, Liu Y, Merry DE, Ho SM, Knudsen KE. Cyclin D1 repressor domain mediates proliferation and survival in prostate cancer Oncogene. 28: 1016-1027. PMID 19079343 DOI: 10.1038/Onc.2008.446 |
0.359 |
|
| 2007 |
Yang Z, Chang YJ, Yu IC, Yeh S, Wu CC, Miyamoto H, Merry DE, Sobue G, Chen LM, Chang SS, Chang C. ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor. Nature Medicine. 13: 348-53. PMID 17334372 DOI: 10.1038/Nm1547 |
0.491 |
|
| 2007 |
Li M, Chevalier-Larsen ES, Merry DE, Diamond MI. Soluble androgen receptor oligomers underlie pathology in a mouse model of spinobulbar muscular atrophy. The Journal of Biological Chemistry. 282: 3157-64. PMID 17121819 DOI: 10.1074/jbc.M609972200 |
0.428 |
|
| 2004 |
Chevalier-Larsen ES, O'Brien CJ, Wang H, Jenkins SC, Holder L, Lieberman AP, Merry DE. Castration restores function and neurofilament alterations of aged symptomatic males in a transgenic mouse model of spinal and bulbar muscular atrophy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4778-86. PMID 15152038 DOI: 10.1523/JNEUROSCI.0808-04.2004 |
0.443 |
|
| 2002 |
Walcott JL, Merry DE. Trinucleotide repeat disease. The androgen receptor in spinal and bulbar muscular atrophy. Vitamins and Hormones. 65: 127-47. PMID 12481545 |
0.354 |
|
| 2002 |
Chan HY, Warrick JM, Andriola I, Merry D, Bonini NM. Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila. Human Molecular Genetics. 11: 2895-904. PMID 12393801 DOI: 10.1093/Hmg/11.23.2895 |
0.533 |
|
| 2002 |
Bailey CK, Andriola IF, Kampinga HH, Merry DE. Molecular chaperones enhance the degradation of expanded polyglutamine repeat androgen receptor in a cellular model of spinal and bulbar muscular atrophy. Human Molecular Genetics. 11: 515-23. PMID 11875046 |
0.402 |
|
| 2001 |
Merry DE. Molecular pathogenesis of spinal and bulbar muscular atrophy Brain Research Bulletin. 56: 203-207. PMID 11719251 DOI: 10.1016/S0361-9230(01)00594-9 |
0.487 |
|
| 2001 |
Abel A, Walcott J, Woods J, Duda J, Merry DE. Expression of expanded repeat androgen receptor produces neurologic disease in transgenic mice Human Molecular Genetics. 10: 107-116. PMID 11152658 |
0.472 |
|
| 2000 |
McCampbell A, Taylor JP, Taye AA, Robitschek J, Li M, Walcott J, Merry D, Chai Y, Paulson H, Sobue G, Fischbeck KH. CREB-binding protein sequestration by expanded polyglutamine. Human Molecular Genetics. 9: 2197-202. PMID 10958659 DOI: 10.1093/Hmg/9.14.2197 |
0.505 |
|
| 1999 |
Fischbeck KH, Lieberman A, Bailey CK, Abel A, Merry DE. Androgen receptor mutation in Kennedy's disease. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 354: 1075-8. PMID 10434308 DOI: 10.1098/rstb.1999.0461 |
0.391 |
|
| 1998 |
Kobayashi Y, Miwa S, Merry DE, Kume A, Mei L, Doyu M, Sobue G. Caspase-3 cleaves the expanded androgen receptor protein of spinal and bulbar muscular atrophy in a polyglutamine repeat length-dependent manner Biochemical and Biophysical Research Communications. 252: 145-150. PMID 9813160 DOI: 10.1006/bbrc.1998.9624 |
0.485 |
|
| 1998 |
Li M, Nakagomi Y, Kobayashi Y, Merry DE, Tanaka F, Doyu M, Mitsuma T, Hashizume Y, Fischbeck KH, Sobue G. Nonneural nuclear inclusions of androgen receptor protein in spinal and bulbar muscular atrophy. The American Journal of Pathology. 153: 695-701. PMID 9736019 DOI: 10.1016/S0002-9440(10)65612-X |
0.467 |
|
| 1998 |
Li M, Miwa S, Kobayashi Y, Merry DE, Yamamoto M, Tanaka F, Doyu M, Hashizume Y, Fischbeck KH, Sobue G. Nuclear inclusions of the androgen receptor protein in spinal and bulbar muscular atrophy. Annals of Neurology. 44: 249-54. PMID 9708548 DOI: 10.1002/ana.410440216 |
0.511 |
|
| 1998 |
Merry DE, Kobayashi Y, Bailey CK, Taye AA, Fischbeck KH. Cleavage, aggregation and toxicity of the expanded androgen receptor in spinal and bulbar muscular atrophy. Human Molecular Genetics. 7: 693-701. PMID 9499423 DOI: 10.1093/hmg/7.4.693 |
0.568 |
|
| 1998 |
Brooks BP, Merry DE, Paulson HL, Lieberman AP, Kolson DL, Fischbeck KH. A cell culture model for androgen effects in motor neurons. Journal of Neurochemistry. 70: 1054-60. PMID 9489725 DOI: 10.1046/J.1471-4159.1998.70031054.X |
0.37 |
|
| 1997 |
Brooks BP, Paulson HL, Merry DE, Salazar-Grueso EF, Brinkmann AO, Wilson EM, Fischbeck KH. Characterization of an expanded glutamine repeat androgen receptor in a neuronal cell culture system. Neurobiology of Disease. 3: 313-23. PMID 9173928 DOI: 10.1006/nbdi.1997.0126 |
0.461 |
|
| 1996 |
Koshy B, Matilla T, Burright EN, Merry DE, Fischbeck KH, Orr HT, Zoghbi HY. Spinocerebellar ataxia type-1 and spinobulbar muscular atrophy gene products interact with glyceraldehyde-3-phosphate dehydrogenase. Human Molecular Genetics. 5: 1311-8. PMID 8872471 DOI: 10.1093/Hmg/5.9.1311 |
0.333 |
|
| 1996 |
Pekosz A, Phillips J, Pleasure D, Merry D, Gonzalez-Scarano F. Induction of apoptosis by La Crosse virus infection and role of neuronal differentiation and human bcl-2 expression in its prevention Journal of Virology. 70: 5329-5335. PMID 8764043 DOI: 10.1128/Jvi.70.8.5329-5335.1996 |
0.311 |
|
| 1995 |
Bingham PM, Scott MO, Wang S, McPhaul MJ, Wilson EM, Garbern JY, Merry DE, Fischbeck KH. Stability of an expanded trinucleotide repeat in the androgen receptor gene in transgenic mice. Nature Genetics. 9: 191-6. PMID 7719348 DOI: 10.1038/ng0295-191 |
0.329 |
|
| 1994 |
Merry DE, Veis DJ, Hickey WF, Korsmeyer SJ. bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS. Development (Cambridge, England). 120: 301-11. PMID 8149910 |
0.303 |
|
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