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Hiroaki Suga - Publications

Affiliations: 
1997-2003 State University of New York, Buffalo, Buffalo, NY, United States 
 2003- University of Tokyo, Bunkyō-ku, Tōkyō-to, Japan 
Area:
Organic Chemistry, Biochemistry
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194 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Goto Y, Suga H. The RaPID Platform for the Discovery of Pseudo-Natural Macrocyclic Peptides. Accounts of Chemical Research. 54: 3604-3617. PMID 34505781 DOI: 10.1021/acs.accounts.1c00391  0.316
2021 Kimura H, Suga H. Incorporation of backbone modifications in mRNA-displayable peptides. Methods in Enzymology. 656: 521-544. PMID 34325797 DOI: 10.1016/bs.mie.2021.05.015  0.304
2021 Iwane Y, Kimura H, Katoh T, Suga H. Uniform affinity-tuning of N-methyl-aminoacyl-tRNAs to EF-Tu enhances their multiple incorporation. Nucleic Acids Research. PMID 33997906 DOI: 10.1093/nar/gkab288  0.302
2020 Katoh T, Suga H. Ribosomal Elongation of Aminobenzoic Acid Derivatives. Journal of the American Chemical Society. 142: 16518-16522. PMID 32946698 DOI: 10.1021/Jacs.0C05765  0.388
2020 Katoh T, Sengoku T, Hirata K, Ogata K, Suga H. Ribosomal synthesis and de novo discovery of bioactive foldamer peptides containing cyclic β-amino acids. Nature Chemistry. PMID 32839601 DOI: 10.1038/S41557-020-0525-1  0.403
2020 Vinogradov AA, Suga H. Introduction to Thiopeptides: Biological Activity, Biosynthesis, and Strategies for Functional Reprogramming. Cell Chemical Biology. PMID 32698017 DOI: 10.1016/J.Chembiol.2020.07.003  0.322
2020 Vinogradov AA, Shimomura M, Kano N, Goto Y, Onaka H, Suga H. Promiscuous enzymes cooperate at the substrate level en route to lactazole A. Journal of the American Chemical Society. PMID 32664727 DOI: 10.1021/Jacs.0C05541  0.328
2020 Hazama D, Yin Y, Murata Y, Matsuda M, Okamoto T, Tanaka D, Terasaka N, Zhao J, Sakamoto M, Kakuchi Y, Saito Y, Kotani T, Nishimura Y, Nakagawa A, Suga H, et al. Macrocyclic Peptide-Mediated Blockade of the CD47-SIRPα Interaction as a Potential Cancer Immunotherapy. Cell Chemical Biology. PMID 32640189 DOI: 10.1016/J.Chembiol.2020.06.008  0.332
2020 Okuma R, Kuwahara T, Yoshikane T, Watanabe M, Dranchak P, Inglese J, Shuto S, Goto Y, Suga H. A macrocyclic peptide library with a structurally constrained cyclopropane-containing building block leads to thiol-independent inhibitors of phosphoglycerate mutase. Chemistry, An Asian Journal. PMID 32633882 DOI: 10.1002/Asia.202000700  0.419
2020 Shinbara K, Liu W, van Neer RHP, Katoh T, Suga H. Methodologies for Backbone Macrocyclic Peptide Synthesis Compatible With Screening Technologies. Frontiers in Chemistry. 8: 447. PMID 32626683 DOI: 10.3389/Fchem.2020.00447  0.379
2020 Vinogradov AA, Shimomura M, Goto Y, Ozaki T, Asamizu S, Sugai Y, Suga H, Onaka H. Minimal lactazole scaffold for in vitro thiopeptide bioengineering. Nature Communications. 11: 2272. PMID 32385237 DOI: 10.1038/S41467-020-16145-4  0.349
2020 Johansen-Leete J, Passioura T, Foster S, Bhusal RP, Ford D, Liu M, Jongkees SAK, Suga H, Stone MJ, Payne RJ. Discovery of Potent Cyclic Sulfopeptide Chemokine Inhibitors via Reprogrammed Genetic Code mRNA Display. Journal of the American Chemical Society. PMID 32330017 DOI: 10.1021/Jacs.0C03152  0.338
2020 Tsiamantas C, Rogers JM, Suga H. Initiating ribosomal peptide synthesis with exotic building blocks. Chemical Communications (Cambridge, England). 56: 4265-4272. PMID 32267262 DOI: 10.1039/D0Cc01291B  0.399
2020 Ishida S, Terasaka N, Katoh T, Suga H. An aminoacylation ribozyme evolved from a natural tRNA-sensing T-box riboswitch. Nature Chemical Biology. PMID 32203413 DOI: 10.1038/S41589-020-0500-6  0.358
2020 Koike K, Nagano M, Ebihara M, Hirayama T, Tsuji M, Suga H, Nagasawa H. Design, Synthesis, and Conformation-Activity Study of Unnatural Bridged Bicyclic Depsipeptides as Highly Potent HIF-1 Inhibitors and Antitumor Agents. Journal of Medicinal Chemistry. PMID 32202785 DOI: 10.1021/Acs.Jmedchem.9B02039  0.354
2020 Katoh T, Suga H. Ribosomal Elongation of Cyclic γ-Amino Acids using a Reprogrammed Genetic Code. Journal of the American Chemical Society. 142: 4965-4969. PMID 32129615 DOI: 10.1021/Jacs.9B12280  0.368
2020 Fleming SR, Himes PM, Ghodge SV, Goto Y, Suga H, Bowers AA. Exploring the Post-Translational Enzymology of PaaA by mRNA Display. Journal of the American Chemical Society. PMID 32109054 DOI: 10.1021/Jacs.0C01576  0.337
2020 Suga H, Brik A, Huang Y, Nawatha M. Affinity Maturation of Macrocyclic Peptide Modulators of Lys48-linked Diubiquitin by a Twofold Strategy. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32105365 DOI: 10.1002/Chem.202000273  0.395
2020 Sakurai Y, Mizumura W, Ito K, Iwasaki K, Katoh T, Goto Y, Suga H, Harashima H. Improved stability of siRNA-loaded lipid nanoparticles prepared with a PEG-monoacyl fatty acid facilitates ligand-mediated siRNA delivery. Molecular Pharmaceutics. PMID 32091909 DOI: 10.1021/Acs.Molpharmaceut.0C00087  0.359
2020 Tsiamantas C, Kwon S, Rogers JM, Douat C, Huc I, Suga H. Ribosomal incorporation of aromatic oligoamides as peptide side-chain appendages. Angewandte Chemie (International Ed. in English). PMID 31894626 DOI: 10.1002/Anie.201914654  0.373
2020 Nagano M, Suga H. Expansion of Modality: Peptides to Pseudo-Natural Macrocyclic Peptides Journal of Synthetic Organic Chemistry Japan. 78: 516-526. DOI: 10.5059/Yukigoseikyokaishi.78.516  0.334
2019 Maini R, Kimura H, Takatsuji R, Katoh T, Goto Y, Suga H. Ribosomal Formation of Thioamide Bond in Polypeptide Synthesis. Journal of the American Chemical Society. PMID 31815469 DOI: 10.1021/Jacs.9B11097  0.409
2019 Yin Y, Ochi N, Craven TW, Baker D, Takigawa N, Suga H. De novo carborane-containing macrocyclic peptides targeting human EGFR. Journal of the American Chemical Society. PMID 31752491 DOI: 10.1021/Jacs.9B09106  0.416
2019 Kato Y, Kuroda T, Huang Y, Ohta R, Goto Y, Suga H. Chemoenzymatic posttranslational modification reactions for the synthesis of Ψ[CH2NH]-containing peptides. Angewandte Chemie (International Ed. in English). PMID 31622000 DOI: 10.1002/Anie.201910894  0.366
2019 Goto Y, Suga H. In vitro biosynthesis of peptides containing exotic azoline analogs. Chembiochem : a European Journal of Chemical Biology. PMID 31523895 DOI: 10.1002/Cbic.201900521  0.408
2019 Passioura T, Liu W, Dunkelmann D, Higuchi T, Suga H. Correction to "Display Selection of Exotic Macrocyclic Peptides Expressed Under a Radically Reprogrammed 23 Amino Acid Genetic Code". Journal of the American Chemical Society. PMID 31287675 DOI: 10.1021/Jacs.9B06806  0.353
2019 Tran STP, Hipolito CJ, Suzuki H, Xie R, Kim Tuyen HD, Dijke PT, Terasaka N, Goto Y, Suga H, Kato M. Generation of non-standard macrocyclic peptides specifically binding TSC-22 homologous gene-1. Biochemical and Biophysical Research Communications. PMID 31227214 DOI: 10.1016/J.Bbrc.2019.06.035  0.367
2019 Nawatha M, Rogers JM, Bonn SM, Livneh I, Lemma B, Mali SM, Vamisetti GB, Sun H, Bercovich B, Huang Y, Ciechanover A, Fushman D, Suga H, Brik A. De novo macrocyclic peptides that specifically modulate Lys48-linked ubiquitin chains. Nature Chemistry. PMID 31182821 DOI: 10.1038/S41557-019-0278-X  0.383
2019 Tsiamantas C, Kwon S, Douat C, Huc I, Suga H. Optimizing aromatic oligoamide foldamer side-chains for ribosomal translation initiation. Chemical Communications (Cambridge, England). PMID 31172994 DOI: 10.1039/C9Cc03547H  0.36
2019 Hirose H, Hideshima T, Katoh T, Suga H. A Case Study on the Keap1 Interaction with Peptide Sequence Epitopes Selected by the Peptidomic mRNA Display. Chembiochem : a European Journal of Chemical Biology. PMID 31169361 DOI: 10.1002/Cbic.201900039  0.385
2019 Tsiamantas C, Otero-Ramirez ME, Suga H. Discovery of Functional Macrocyclic Peptides by Means of the RaPID System. Methods in Molecular Biology (Clifton, N.J.). 2001: 299-315. PMID 31134577 DOI: 10.1007/978-1-4939-9504-2_14  0.407
2019 Sakai K, Passioura T, Sato H, Ito K, Furuhashi H, Umitsu M, Takagi J, Kato Y, Mukai H, Warashina S, Zouda M, Watanabe Y, Yano S, Shibata M, Suga H, et al. Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor. Nature Chemical Biology. 15: 598-606. PMID 31101918 DOI: 10.1038/S41589-019-0285-7  0.344
2019 Fujino T, Kondo T, Suga H, Murakami H. Exploring of minimal RNA substrate of flexizymes. Chembiochem : a European Journal of Chemical Biology. PMID 30950544 DOI: 10.1002/Cbic.201900150  0.319
2019 Katoh T, Suga H. Flexizyme-catalyzed synthesis of 3'-aminoacyl-NH-tRNAs. Nucleic Acids Research. PMID 30843032 DOI: 10.1093/Nar/Gkz143  0.365
2019 Vinogradov AA, Yi Y, Suga H. MACROCYCLIC PEPTIDES AS DRUG CANDIDATES: RECENT PROGRESS AND REMAINING CHALLENGES. Journal of the American Chemical Society. PMID 30768253 DOI: 10.1021/Jacs.8B13178  0.359
2019 Yin Y, Fei Q, Liu W, Li Z, Suga H, Wu C. Chemical and Ribosomal Synthesis of Topologically Controlled Bicyclic and Tricyclic Peptide Scaffolds Primed by Selenoether Formation. Angewandte Chemie (International Ed. in English). PMID 30762292 DOI: 10.1002/Anie.201813827  0.367
2019 Katoh T, Suga H. Engineering Translation Components Improve Incorporation of Exotic Amino Acids. International Journal of Molecular Sciences. 20. PMID 30691159 DOI: 10.3390/Ijms20030522  0.363
2019 Takatsuji R, Shinbara K, Katoh T, Goto Y, Passioura T, Yajima R, Komatsu Y, Suga H. Ribosomal synthesis of backbone-cyclic peptides compatible with in vitro display. Journal of the American Chemical Society. PMID 30648857 DOI: 10.1021/Jacs.8B05327  0.399
2019 Fleming SR, Bartges TE, Vinogradov AA, Kirkpatrick CL, Goto Y, Suga H, Hicks LM, Bowers AA. Flexizyme-enabled benchtop biosynthesis of thiopeptides. Journal of the American Chemical Society. PMID 30602112 DOI: 10.1021/Jacs.8B11521  0.337
2018 Katoh T, Passioura T, Suga H. Advances in genetic code reprogramming in 2014-2017. Synthetic Biology (Oxford, England). 3: ysy008. PMID 32995516 DOI: 10.1093/Synbio/Ysy008  0.351
2018 Passioura T, Bhushan B, Tumber A, Kawamura A, Suga H. Corrigendum to "Structure-activity studies of a macrocyclic peptide inhibitor of histone lysine demethylase 4A" [Bioorg. Med. Chem. 26/6 (2018) 1225-1231]. Bioorganic & Medicinal Chemistry. PMID 30594451 DOI: 10.1016/J.Bmc.2018.12.020  0.312
2018 Otero-Ramirez ME, Passioura T, Suga H. Structural Features and Binding Modes of Thioether-Cyclized Peptide Ligands. Biomedicines. 6. PMID 30551606 DOI: 10.3390/Biomedicines6040116  0.354
2018 Hirose H, Tsiamantas C, Katoh T, Suga H. In vitro expression of genetically encoded non-standard peptides consisting of exotic amino acid building blocks. Current Opinion in Biotechnology. 58: 28-36. PMID 30453154 DOI: 10.1016/J.Copbio.2018.10.012  0.39
2018 Miao W, Sakai K, Ozawa N, Nishiuchi T, Suzuki Y, Ito K, Morioka T, Umitsu M, Takagi J, Suga H, Matsumoto K. Cellular signaling and gene expression profiles evoked by a bivalent macrocyclic peptide that serves as an artificial MET receptor agonist. Scientific Reports. 8: 16492. PMID 30405161 DOI: 10.1038/S41598-018-34835-4  0.331
2018 Huang Y, Wiedmann MM, Suga H. RNA Display Methods for the Discovery of Bioactive Macrocycles. Chemical Reviews. PMID 30395448 DOI: 10.1021/Acs.Chemrev.8B00430  0.389
2018 Decoene KW, Vannecke W, Passioura T, Suga H, Madder A. Pyrrole-Mediated Peptide Cyclization Identified through Genetically Reprogrammed Peptide Synthesis. Biomedicines. 6. PMID 30380792 DOI: 10.3390/Biomedicines6040099  0.389
2018 Miao W, Sakai K, Imamura R, Ito K, Suga H, Sakuma T, Yamamoto T, Matsumoto K. MET Activation by a Macrocyclic Peptide Agonist that Couples to Biological Responses Differently from HGF in a Context-Dependent Manner. International Journal of Molecular Sciences. 19. PMID 30322054 DOI: 10.3390/Ijms19103141  0.332
2018 Rogers JM, Passioura T, Suga H. Nonproteinogenic deep mutational scanning of linear and cyclic peptides. Proceedings of the National Academy of Sciences of the United States of America. PMID 30301798 DOI: 10.1073/Pnas.1809901115  0.402
2018 Katoh T, Suga H. Ribosomal Incorporation of Consecutive β-Amino Acids. Journal of the American Chemical Society. 140: 12159-12167. PMID 30221942 DOI: 10.1021/Jacs.8B07247  0.359
2018 Passioura T, Liu W, Dunkelmann DL, Higuchi T, Suga H. Display selection of exotic macrocyclic peptides expressed under a radically reprogrammed 23 amino acid genetic code. Journal of the American Chemical Society. PMID 30157372 DOI: 10.1021/Jacs.8B03367  0.393
2018 Tajima K, Katoh T, Suga H. Genetic code expansion via integration of redundant amino acid assignment by finely tuning tRNA pools. Current Opinion in Chemical Biology. PMID 30072241 DOI: 10.1016/J.Cbpa.2018.07.010  0.337
2018 Goto Y, Suga H. Engineering of RiPP pathways for the production of artificial peptides bearing various non-proteinogenic structures. Current Opinion in Chemical Biology. 46: 82-90. PMID 29957445 DOI: 10.1016/J.Cbpa.2018.06.014  0.367
2018 McAllister TE, Yeh TL, Abboud MI, Leung IKH, Hookway ES, King ONF, Bhushan B, Williams ST, Hopkinson RJ, Münzel M, Loik ND, Chowdhury R, Oppermann U, Claridge TDW, Goto Y, ... Suga H, et al. Non-competitive cyclic peptides for targeting enzyme-substrate complexes. Chemical Science. 9: 4569-4578. PMID 29899950 DOI: 10.1039/C8Sc00286J  0.403
2018 Rogers JM, Kwon S, Dawson SJ, Mandal PK, Suga H, Huc I. Publisher Correction: Ribosomal synthesis and folding of peptide-helical aromatic foldamer hybrids. Nature Chemistry. PMID 29855558 DOI: 10.1038/S41557-018-0086-8  0.344
2018 Passioura T, Watashi K, Fukano K, Shimura S, Saso W, Morishita R, Ogasawara Y, Tanaka Y, Mizokami M, Sureau C, Suga H, Wakita T. De Novo Macrocyclic Peptide Inhibitors of Hepatitis B Virus Cellular Entry. Cell Chemical Biology. PMID 29779957 DOI: 10.1016/J.Chembiol.2018.04.011  0.302
2018 Bashiruddin N, Matsunaga Y, Nagano M, Takagi J, Suga H. Facile synthesis of dimeric thioether-macrocyclic peptides with antibody-like affinity against Plexin-B1. Bioconjugate Chemistry. PMID 29714478 DOI: 10.1021/Acs.Bioconjchem.8B00219  0.385
2018 Nishio K, Belle R, Katoh T, Kawamura A, Sengoku T, Hanada K, Ohsawa N, Shirouzu M, Yokoyama S, Suga H. Thioether Macrocyclic Peptides Selected against TET1 Compact Catalytic Domain Inhibit TET1 Catalytic Activity. Chembiochem : a European Journal of Chemical Biology. PMID 29665240 DOI: 10.1002/Cbic.201800047  0.394
2018 Rogers JM, Kwon S, Dawson SJ, Mandal PK, Suga H, Huc I. Ribosomal synthesis and folding of peptide-helical aromatic foldamer hybrids. Nature Chemistry. PMID 29556052 DOI: 10.1038/S41557-018-0007-X  0.411
2018 Iwane Y, Katoh T, Goto Y, Suga H. Artificial Division of Codon Boxes for Expansion of the Amino Acid Repertoire of Ribosomal Polypeptide Synthesis. Methods in Molecular Biology (Clifton, N.J.). 1728: 17-47. PMID 29404989 DOI: 10.1007/978-1-4939-7574-7_2  0.366
2018 Passioura T, Bhushan B, Tumber A, Kawamura A, Suga H. Structure-activity studies of a macrocyclic peptide inhibitor of histone lysine demethylase 4A. Bioorganic & Medicinal Chemistry. PMID 29402611 DOI: 10.1016/J.Bmc.2018.01.013  0.376
2018 Kusakizako T, Tanaka Y, Hipolito CJ, Suga H, Nureki O. Crystallographic Analysis of MATE-Type Multidrug Exporter with Its Inhibitors. Methods in Molecular Biology (Clifton, N.J.). 1700: 37-57. PMID 29177824 DOI: 10.1007/978-1-4939-7454-2_3  0.318
2018 Goto Y, Suga H. Artificial In Vitro Biosynthesis Systems for the Development of Pseudo-Natural Products Bulletin of the Chemical Society of Japan. 91: 410-419. DOI: 10.1246/Bcsj.20170379  0.324
2017 Taylor RD, Rey-Carrizo M, Passioura T, Suga H. Identification of nonstandard macrocyclic peptide ligands through display screening. Drug Discovery Today. Technologies. 26: 17-23. PMID 29249238 DOI: 10.1016/J.Ddtec.2017.10.005  0.353
2017 Katoh T, Iwane Y, Suga H. Logical engineering of D-arm and T-stem of tRNA that enhances d-amino acid incorporation. Nucleic Acids Research. PMID 29155943 DOI: 10.1093/Nar/Gkx1129  0.311
2017 Sakurai Y, Mizumura W, Murata M, Hada T, Yamamoto S, Ito K, Iwasaki K, Katoh T, Goto Y, Takagi A, Kohara M, Suga H, Harashima H. Efficient siRNA delivery by lipid nanoparticles modified with a non-standard macrocyclic peptide for EpCAM-targeting. Molecular Pharmaceutics. PMID 28789523 DOI: 10.1021/Acs.Molpharmaceut.7B00362  0.307
2017 Walport LJ, Obexer R, Suga H. Strategies for transitioning macrocyclic peptides to cell-permeable drug leads. Current Opinion in Biotechnology. 48: 242-250. PMID 28783603 DOI: 10.1016/J.Copbio.2017.07.007  0.36
2017 Danhart EM, Bakhtina M, Cantara WA, Kuzmishin AB, Ma X, Sanford BL, Košutić M, Goto Y, Suga H, Nakanishi K, Micura R, Foster MP, Musier-Forsyth K. Conformational and chemical selection by a trans-acting editing domain. Proceedings of the National Academy of Sciences of the United States of America. PMID 28768811 DOI: 10.1073/Pnas.1703925114  0.368
2017 Bacusmo JM, Kuzmishin AB, Cantara WA, Goto Y, Suga H, Musier-Forsyth K. Quality control by trans-editing factor prevents global mistranslation of non-protein amino acid α-aminobutyrate. Rna Biology. 0. PMID 28737471 DOI: 10.1080/15476286.2017.1353846  0.351
2017 Katoh T, Iwane Y, Suga H. tRNA engineering for manipulating genetic code. Rna Biology. 0. PMID 28722545 DOI: 10.1080/15476286.2017.1343227  0.333
2017 Shin BS, Katoh T, Gutierrez E, Kim JR, Suga H, Dever TE. Amino acid substrates impose polyamine, eIF5A, or hypusine requirement for peptide synthesis. Nucleic Acids Research. PMID 28637321 DOI: 10.1093/Nar/Gkx532  0.439
2017 Song X, Lu LY, Passioura T, Suga H. Macrocyclic peptide inhibitors for the protein-protein interaction of Zaire Ebola virus protein 24 and karyopherin alpha 5. Organic & Biomolecular Chemistry. PMID 28574091 DOI: 10.1039/C7Ob00012J  0.306
2017 Jongkees SAK, Umemoto S, Suga H. Linker-free incorporation of carbohydrates into displayed macrocyclic peptides. Chemical Science. 8: 1474-1481. PMID 28572907 DOI: 10.1039/C6Sc04381J  0.422
2017 Kawamura A, Münzel M, Kojima T, Yapp C, Bhushan B, Goto Y, Tumber A, Katoh T, King ON, Passioura T, Walport LJ, Hatch SB, Madden S, Müller S, Brennan PE, ... ... Suga H, et al. Highly selective inhibition of histone demethylases by de novo macrocyclic peptides. Nature Communications. 8: 14773. PMID 28382930 DOI: 10.1038/Ncomms14773  0.369
2017 Yu H, Dranchak P, Li Z, MacArthur R, Munson MS, Mehzabeen N, Baird NJ, Battalie KP, Ross D, Lovell S, Carlow CK, Suga H, Inglese J. Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases. Nature Communications. 8: 14932. PMID 28368002 DOI: 10.1038/Ncomms14932  0.392
2017 Obexer R, Walport LJ, Suga H. Exploring sequence space: harnessing chemical and biological diversity towards new peptide leads. Current Opinion in Chemical Biology. 38: 52-61. PMID 28319812 DOI: 10.1016/J.Cbpa.2017.02.020  0.384
2017 Jongkees SA, Caner S, Tysoe C, Brayer GD, Withers SG, Suga H. Rapid Discovery of Potent and Selective Glycosidase-Inhibiting De Novo Peptides. Cell Chemical Biology. PMID 28262556 DOI: 10.1016/J.Chembiol.2017.02.001  0.382
2017 Ozaki T, Yamashita K, Goto Y, Shimomura M, Hayashi S, Asamizu S, Sugai Y, Ikeda H, Suga H, Onaka H. Dissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivo. Nature Communications. 8: 14207. PMID 28165449 DOI: 10.1038/Ncomms14207  0.391
2017 Passioura T, Suga H. A RaPID way to discover nonstandard macrocyclic peptide modulators of drug targets. Chemical Communications (Cambridge, England). PMID 28091672 DOI: 10.1039/C6Cc06951G  0.401
2016 Katoh T, Tajima K, Suga H. Consecutive Elongation of D-Amino Acids in Translation. Cell Chemical Biology. PMID 28042044 DOI: 10.1016/J.Chembiol.2016.11.012  0.334
2016 Matsunaga Y, Bashiruddin NK, Kitago Y, Takagi J, Suga H. Allosteric Inhibition of a Semaphorin 4D Receptor Plexin B1 by a High-Affinity Macrocyclic Peptide. Cell Chemical Biology. 23: 1341-1350. PMID 27984026 DOI: 10.1016/J.Chembiol.2016.09.015  0.348
2016 Terasaka N, Futai K, Katoh T, Suga H. A human microRNA precursor binding to folic acid discovered by small RNA transcriptomic SELEX. Rna (New York, N.Y.). 22: 1918-1928. PMID 27852928 DOI: 10.1261/Rna.057737.116  0.312
2016 Hwang DW, Bang NY, Ito K, Ha S, Kim MY, Lee E, Suga H, Lee DS. In vivo targeting of c-Met using a non-standard macrocyclic peptide in gastric carcinoma. Cancer Letters. PMID 27810404 DOI: 10.1016/J.Canlet.2016.10.030  0.346
2016 Maini R, Umemoto S, Suga H. Ribosome-mediated synthesis of natural product-like peptides via cell-free translation. Current Opinion in Chemical Biology. 34: 44-52. PMID 27344230 DOI: 10.1016/J.Cbpa.2016.06.006  0.385
2016 Katoh T, Wohlgemuth I, Nagano M, Rodnina MV, Suga H. Essential structural elements in tRNA(Pro) for EF-P-mediated alleviation of translation stalling. Nature Communications. 7: 11657. PMID 27216360 DOI: 10.1038/Ncomms11657  0.337
2016 Lee KB, Hou CY, Kim CE, Kim DM, Suga H, Kang TJ. Genetic Code Expansion by Degeneracy Reprogramming of Arginyl Codons. Chembiochem : a European Journal of Chemical Biology. PMID 27151886 DOI: 10.1002/Cbic.201600111  0.32
2016 Iwane Y, Hitomi A, Murakami H, Katoh T, Goto Y, Suga H. Expanding the amino acid repertoire of ribosomal polypeptide synthesis via the artificial division of codon boxes. Nature Chemistry. 8: 317-25. PMID 27001726 DOI: 10.1038/Nchem.2446  0.356
2016 Kostic M, Crews CM, Hertweck C, Shokat K, Suga H. Cell Chemical Biology: Home of Exciting Chemical Biology. Cell Chemical Biology. 23: 1-2. PMID 26933730 DOI: 10.1016/J.Chembiol.2016.01.001  0.326
2016 Hipolito CJ, Nishio K, Suga H. In Vitro Selected Macrocyclic Peptides: Tools for Regulating the Conformational Freedom of Transmembrane Proteins. Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. 136: 191-6. PMID 26831792 DOI: 10.1248/Yakushi.15-00229-4  0.372
2016 Fujino T, Goto Y, Suga H, Murakami H. Ribosomal Synthesis of Peptides with Multiple β-Amino Acids. Journal of the American Chemical Society. PMID 26807980 DOI: 10.1021/Jacs.5B12482  0.335
2016 Goto Y, Suga H. A Post-translational Cyclodehydratase, PatD, Tolerates Sequence Variation in the C-terminal Region of Substrate Peptides Chemistry Letters. 45: 1247-1249. DOI: 10.1246/Cl.160562  0.353
2015 Iwasaki K, Goto Y, Katoh T, Yamashita T, Kaneko S, Suga H. A Fluorescent Imaging Probe Based on a Macrocyclic Scaffold That Binds to Cellular EpCAM. Journal of Molecular Evolution. PMID 26553371 DOI: 10.1007/S00239-015-9710-Z  0.325
2015 Rogers JM, Suga H. Discovering functional, non-proteinogenic amino acid containing, peptides using genetic code reprogramming. Organic & Biomolecular Chemistry. 13: 9353-63. PMID 26280393 DOI: 10.1039/C5Ob01336D  0.391
2015 Bashiruddin NK, Nagano M, Suga H. Synthesis of fused tricyclic peptides using a reprogrammed translation system and chemical modification. Bioorganic Chemistry. 61: 45-50. PMID 26117092 DOI: 10.1016/J.Bioorg.2015.06.002  0.38
2015 Liu Z, Vargas-Rodriguez O, Goto Y, Novoa EM, Ribas de Pouplana L, Suga H, Musier-Forsyth K. Homologous trans-editing factors with broad tRNA specificity prevent mistranslation caused by serine/threonine misactivation. Proceedings of the National Academy of Sciences of the United States of America. 112: 6027-32. PMID 25918376 DOI: 10.1073/Pnas.1423664112  0.372
2015 Terasaka N, Iwane Y, Geiermann AS, Goto Y, Suga H. Recent developments of engineered translational machineries for the incorporation of non-canonical amino acids into polypeptides. International Journal of Molecular Sciences. 16: 6513-31. PMID 25803109 DOI: 10.3390/Ijms16036513  0.344
2015 Ito K, Sakai K, Suzuki Y, Ozawa N, Hatta T, Natsume T, Matsumoto K, Suga H. Artificial human Met agonists based on macrocycle scaffolds. Nature Communications. 6: 6373. PMID 25758345 DOI: 10.1038/Ncomms7373  0.333
2015 Novoa EM, Vargas-Rodriguez O, Lange S, Goto Y, Suga H, Musier-Forsyth K, Ribas de Pouplana L. Ancestral AlaX editing enzymes for control of genetic code fidelity are not tRNA-specific. The Journal of Biological Chemistry. 290: 10495-503. PMID 25724653 DOI: 10.1074/Jbc.M115.640060  0.335
2015 Morioka T, Loik ND, Hipolito CJ, Goto Y, Suga H. Selection-based discovery of macrocyclic peptides for the next generation therapeutics. Current Opinion in Chemical Biology. 26: 34-41. PMID 25703142 DOI: 10.1016/J.Cbpa.2015.01.023  0.373
2015 Bashiruddin NK, Suga H. Construction and screening of vast libraries of natural product-like macrocyclic peptides using in vitro display technologies. Current Opinion in Chemical Biology. 24: 131-8. PMID 25483262 DOI: 10.1016/J.Cbpa.2014.11.011  0.385
2015 Jongkees SAK, Hipolito CJ, Rogers JM, Suga H. Model foldamers: Applications and structures of stable macrocyclic peptides identified using in vitro selection New Journal of Chemistry. 39: 3197-3207. DOI: 10.1039/C4Nj01633E  0.417
2014 Torikai K, Suga H. Ribosomal synthesis of an amphotericin-B inspired macrocycle. Journal of the American Chemical Society. 136: 17359-61. PMID 25454254 DOI: 10.1021/Ja508648S  0.709
2014 Desai BJ, Goto Y, Cembran A, Fedorov AA, Almo SC, Gao J, Suga H, Gerlt JA. Investigating the role of a backbone to substrate hydrogen bond in OMP decarboxylase using a site-specific amide to ester substitution. Proceedings of the National Academy of Sciences of the United States of America. 111: 15066-71. PMID 25275007 DOI: 10.1073/Pnas.1411772111  0.303
2014 Passioura T, Suga H. Reprogramming the genetic code in vitro. Trends in Biochemical Sciences. 39: 400-8. PMID 25129886 DOI: 10.1016/J.Tibs.2014.07.005  0.347
2014 Goto Y, Ito Y, Kato Y, Tsunoda S, Suga H. One-pot synthesis of azoline-containing peptides in a cell-free translation system integrated with a posttranslational cyclodehydratase. Chemistry & Biology. 21: 766-74. PMID 24856821 DOI: 10.1016/J.Chembiol.2014.04.008  0.384
2014 Hipolito CJ, Bashiruddin NK, Suga H. Protein cocrystallization molecules originating from in vitro selected macrocyclic peptides. Current Opinion in Structural Biology. 26: 24-31. PMID 24681557 DOI: 10.1016/J.Sbi.2014.03.001  0.325
2014 Shimada T, Shimada K, Matsui M, Kitai Y, Igarashi J, Suga H, Ishihama A. Roles of cell division control factor SdiA: recognition of quorum sensing signals and modulation of transcription regulation targets. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 19: 405-18. PMID 24645791 DOI: 10.1111/Gtc.12139  0.325
2014 Passioura T, Katoh T, Goto Y, Suga H. Selection-based discovery of druglike macrocyclic peptides. Annual Review of Biochemistry. 83: 727-52. PMID 24580641 DOI: 10.1146/Annurev-Biochem-060713-035456  0.383
2014 Yamagata K, Goto Y, Nishimasu H, Morimoto J, Ishitani R, Dohmae N, Takeda N, Nagai R, Komuro I, Suga H, Nureki O. Structural basis for potent inhibition of SIRT2 deacetylase by a macrocyclic peptide inducing dynamic structural change. Structure (London, England : 1993). 22: 345-52. PMID 24389023 DOI: 10.1016/J.Str.2013.12.001  0.376
2014 Das M, Vargas-Rodriguez O, Goto Y, Suga H, Musier-Forsyth K. Distinct tRNA recognition strategies used by a homologous family of editing domains prevent mistranslation. Nucleic Acids Research. 42: 3943-53. PMID 24371276 DOI: 10.1093/Nar/Gkt1332  0.316
2014 Passioura T, Suga H. Flexizymes, their evolutionary history and diverse utilities. Topics in Current Chemistry. 344: 331-45. PMID 23478876 DOI: 10.1007/128_2013_421  0.334
2014 Terasaka N, Suga H. Flexizymes-facilitated genetic code reprogramming leading to the discovery of drug-like peptides Chemistry Letters. 43: 11-19. DOI: 10.1246/Cl.130910  0.389
2014 Suga H. Abstract SY05-03: Natural product-inspired peptide drug discovery accelerated by the RaPID system Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Sy05-03  0.346
2013 Goto Y, Iseki M, Hitomi A, Murakami H, Suga H. Nonstandard peptide expression under the genetic code consisting of reprogrammed dual sense codons. Acs Chemical Biology. 8: 2630-4. PMID 24099623 DOI: 10.1021/Cb400549P  0.349
2013 Hipolito CJ, Tanaka Y, Katoh T, Nureki O, Suga H. A macrocyclic peptide that serves as a cocrystallization ligand and inhibits the function of a MATE family transporter. Molecules (Basel, Switzerland). 18: 10514-30. PMID 23999725 DOI: 10.3390/Molecules180910514  0.382
2013 Tanaka Y, Hipolito CJ, Maturana AD, Ito K, Kuroda T, Higuchi T, Katoh T, Kato HE, Hattori M, Kumazaki K, Tsukazaki T, Ishitani R, Suga H, Nureki O. Structural basis for the drug extrusion mechanism by a MATE multidrug transporter. Nature. 496: 247-51. PMID 23535598 DOI: 10.1038/Nature12014  0.345
2013 Passioura T, Suga H. Flexizyme-mediated genetic reprogramming as a tool for noncanonical peptide synthesis and drug discovery. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 6530-6. PMID 23519693 DOI: 10.1002/Chem.201300247  0.36
2013 Kawakami T, Ishizawa T, Fujino T, Reid PC, Suga H, Murakami H. In vitro selection of multiple libraries created by genetic code reprogramming to discover macrocyclic peptides that antagonize VEGFR2 activity in living cells. Acs Chemical Biology. 8: 1205-14. PMID 23517428 DOI: 10.1021/Cb300697H  0.393
2013 Ito K, Passioura T, Suga H. Technologies for the synthesis of mRNA-encoding libraries and discovery of bioactive natural product-inspired non-traditional macrocyclic peptides. Molecules (Basel, Switzerland). 18: 3502-28. PMID 23507778 DOI: 10.3390/Molecules18033502  0.364
2013 Fujino T, Goto Y, Suga H, Murakami H. Reevaluation of the D-amino acid compatibility with the elongation event in translation. Journal of the American Chemical Society. 135: 1830-7. PMID 23301668 DOI: 10.1021/Ja309570X  0.344
2012 Lee KB, Kim HC, Kim DM, Kang TJ, Suga H. Comparative evaluation of two cell-free protein synthesis systems derived from Escherichia coli for genetic code reprogramming. Journal of Biotechnology. 164: 330-5. PMID 23395618 DOI: 10.1016/J.Jbiotec.2013.01.011  0.35
2012 Iwasaki K, Goto Y, Katoh T, Suga H. Selective thioether macrocyclization of peptides having the N-terminal 2-chloroacetyl group and competing two or three cysteine residues in translation. Organic & Biomolecular Chemistry. 10: 5783-6. PMID 22419118 DOI: 10.1039/C2Ob25306B  0.367
2012 Hipolito CJ, Suga H. Ribosomal production and in vitro selection of natural product-like peptidomimetics: the FIT and RaPID systems. Current Opinion in Chemical Biology. 16: 196-203. PMID 22401851 DOI: 10.1016/J.Cbpa.2012.02.014  0.403
2012 Morimoto J, Hayashi Y, Suga H. Discovery of macrocyclic peptides armed with a mechanism-based warhead: isoform-selective inhibition of human deacetylase SIRT2. Angewandte Chemie (International Ed. in English). 51: 3423-7. PMID 22374802 DOI: 10.1002/Anie.201108118  0.351
2012 Goto Y, Suga H. Flexizymes as a tRNA acylation tool facilitating genetic code reprogramming. Methods in Molecular Biology (Clifton, N.J.). 848: 465-78. PMID 22315087 DOI: 10.1007/978-1-61779-545-9_29  0.411
2012 Hayashi Y, Morimoto J, Suga H. In vitro selection of anti-Akt2 thioether-macrocyclic peptides leading to isoform-selective inhibitors. Acs Chemical Biology. 7: 607-13. PMID 22273180 DOI: 10.1021/Cb200388K  0.323
2012 Reid PC, Goto Y, Katoh T, Suga H. Charging of tRNAs using ribozymes and selection of cyclic peptides containing thioethers. Methods in Molecular Biology (Clifton, N.J.). 805: 335-48. PMID 22094815 DOI: 10.1007/978-1-61779-379-0_19  0.393
2012 Kojima T, Hayashi Y, Suga H. Genetic Code Reprogramming Seibutsu Butsuri. 52: 4-9. DOI: 10.2142/Biophys.52.004  0.383
2012 Suga H. Abstract SY06-02: The nontraditional peptide therapeutics Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Sy06-02  0.378
2011 Yamagishi Y, Shoji I, Miyagawa S, Kawakami T, Katoh T, Goto Y, Suga H. Natural product-like macrocyclic N-methyl-peptide inhibitors against a ubiquitin ligase uncovered from a ribosome-expressed de novo library. Chemistry & Biology. 18: 1562-70. PMID 22195558 DOI: 10.1016/J.Chembiol.2011.09.013  0.392
2011 Suga H, Hayashi G, Terasaka N. The RNA origin of transfer RNA aminoacylation and beyond. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 366: 2959-64. PMID 21930588 DOI: 10.1098/Rstb.2011.0137  0.334
2011 Katoh T, Goto Y, Reza MS, Suga H. Ribosomal synthesis of backbone macrocyclic peptides. Chemical Communications (Cambridge, England). 47: 9946-58. PMID 21766105 DOI: 10.1039/C1Cc12647D  0.394
2011 Chung J, Goo E, Yu S, Choi O, Lee J, Kim J, Kim H, Igarashi J, Suga H, Moon JS, Hwang I, Rhee S. Small-molecule inhibitor binding to an N-acyl-homoserine lactone synthase. Proceedings of the National Academy of Sciences of the United States of America. 108: 12089-94. PMID 21730159 DOI: 10.1073/Pnas.1103165108  0.339
2011 Morimoto J, Hayashi Y, Iwasaki K, Suga H. Flexizymes: their evolutionary history and the origin of catalytic function. Accounts of Chemical Research. 44: 1359-68. PMID 21711008 DOI: 10.1021/Ar2000953  0.392
2011 Goto Y, Katoh T, Suga H. Flexizymes for genetic code reprogramming. Nature Protocols. 6: 779-90. PMID 21637198 DOI: 10.1038/Nprot.2011.331  0.413
2011 Kang TJ, Suga H. Translation of a histone H3 tail as a model system for studying peptidyl-tRNA drop-off. Febs Letters. 585: 2269-74. PMID 21627973 DOI: 10.1016/J.Febslet.2011.05.051  0.368
2011 Ohshiro Y, Nakajima E, Goto Y, Fuse S, Takahashi T, Doi T, Suga H. Ribosomal synthesis of backbone-macrocyclic peptides containing γ-amino acids. Chembiochem : a European Journal of Chemical Biology. 12: 1183-7. PMID 21506233 DOI: 10.1002/Cbic.201100104  0.382
2011 Kang TJ, Hayashi Y, Suga H. Synthesis of the backbone cyclic peptide sunflower trypsin inhibitor-1 promoted by the induced peptidyl-tRNA drop-off. Angewandte Chemie (International Ed. in English). 50: 2159-61. PMID 21344575 DOI: 10.1002/Anie.201006963  0.373
2011 Igarashi J, Suga H. Custom synthesis of autoinducers and their analogues. Methods in Molecular Biology (Clifton, N.J.). 692: 265-74. PMID 21031318 DOI: 10.1007/978-1-60761-971-0_19  0.319
2011 Yamaguchi A, Katoh T, Suga H. Drug discovery of non-standard peptide with genetic code reprogramming Drug Delivery System. 26: 584-592. DOI: 10.2745/Dds.26.584  0.331
2011 Ohshiro Y, Nakajima E, Goto Y, Fuse S, Takahashi T, Doi T, Suga H. Cover Picture: Ribosomal Synthesis of Backbone-Macrocyclic Peptides Containing γ-Amino Acids (ChemBioChem 8/2011) Chembiochem. 12: 1137-1137. DOI: 10.1002/Cbic.201190031  0.383
2010 Hayashi G, Goto Y, Suga H. Ribosome evolution for two artificial amino acids in E. coli. Chemistry & Biology. 17: 320-1. PMID 20416503 DOI: 10.1016/J.Chembiol.2010.04.005  0.328
2010 Higuchi T, Suga H. Programmed Synthesis of Natural Product-like Non-standard Peptides Using the Translation System and Its Application Journal of Synthetic Organic Chemistry, Japan. 68: 217-227. DOI: 10.5059/Yukigoseikyokaishi.68.217  0.399
2009 Kawakami T, Ohta A, Ohuchi M, Ashigai H, Murakami H, Suga H. Diverse backbone-cyclized peptides via codon reprogramming. Nature Chemical Biology. 5: 888-90. PMID 19915537 DOI: 10.1038/Nchembio.259  0.401
2009 Goto Y, Iwasaki K, Torikai K, Murakami H, Suga H. Ribosomal synthesis of dehydrobutyrine- and methyllanthionine-containing peptides. Chemical Communications (Cambridge, England). 3419-21. PMID 19503890 DOI: 10.1039/B904314D  0.72
2009 Yamagishi Y, Ashigai H, Goto Y, Murakami H, Suga H. Ribosomal synthesis of cyclic peptides with a fluorogenic oxidative coupling reaction. Chembiochem : a European Journal of Chemical Biology. 10: 1469-72. PMID 19472249 DOI: 10.1002/Cbic.200900021  0.325
2009 Nakajima E, Goto Y, Sako Y, Murakami H, Suga H. Ribosomal synthesis of peptides with C-terminal lactams, thiolactones, and alkylamides. Chembiochem : a European Journal of Chemical Biology. 10: 1186-92. PMID 19370739 DOI: 10.1002/Cbic.200900058  0.382
2009 Niwa N, Yamagishi Y, Murakami H, Suga H. A flexizyme that selectively charges amino acids activated by a water-friendly leaving group. Bioorganic & Medicinal Chemistry Letters. 19: 3892-4. PMID 19364647 DOI: 10.1016/J.Bmcl.2009.03.114  0.345
2009 Murakami H, Ohta A, Suga H. Bases in the anticodon loop of tRNA(Ala)(GGC) prevent misreading. Nature Structural & Molecular Biology. 16: 353-8. PMID 19305404 DOI: 10.1038/Nsmb.1580  0.319
2009 Goto Y, Suga H. Translation initiation with initiator tRNA charged with exotic peptides. Journal of the American Chemical Society. 131: 5040-1. PMID 19301866 DOI: 10.1021/Ja900597D  0.411
2008 Kawakami T, Murakami H, Suga H. Ribosomal synthesis of polypeptoids and peptoid-peptide hybrids. Journal of the American Chemical Society. 130: 16861-3. PMID 19053417 DOI: 10.1021/Ja806998V  0.371
2008 Kang TJ, Yuzawa S, Suga H. Expression of histone H3 tails with combinatorial lysine modifications under the reprogrammed genetic code for the investigation on epigenetic markers. Chemistry & Biology. 15: 1166-74. PMID 19022177 DOI: 10.1016/J.Chembiol.2008.09.014  0.332
2008 Ohta A, Murakami H, Suga H. Polymerization of alpha-hydroxy acids by ribosomes. Chembiochem : a European Journal of Chemical Biology. 9: 2773-8. PMID 18985645 DOI: 10.1002/Cbic.200800439  0.323
2008 Xiao H, Murakami H, Suga H, Ferré-D'Amaré AR. Structural basis of specific tRNA aminoacylation by a small in vitro selected ribozyme. Nature. 454: 358-61. PMID 18548004 DOI: 10.1038/Nature07033  0.4
2008 Goto Y, Murakami H, Suga H. Initiating translation with D-amino acids. Rna (New York, N.Y.). 14: 1390-8. PMID 18515548 DOI: 10.1261/Rna.1020708  0.314
2008 Sako Y, Morimoto J, Murakami H, Suga H. Ribosomal synthesis of bicyclic peptides via two orthogonal inter-side-chain reactions. Journal of the American Chemical Society. 130: 7232-4. PMID 18479111 DOI: 10.1021/Ja800953C  0.387
2008 Sako Y, Goto Y, Murakami H, Suga H. Ribosomal synthesis of peptidase-resistant peptides closed by a nonreducible inter-side-chain bond. Acs Chemical Biology. 3: 241-9. PMID 18338852 DOI: 10.1021/Cb800010P  0.391
2008 Ohta A, Yamagishi Y, Suga H. Synthesis of biopolymers using genetic code reprogramming. Current Opinion in Chemical Biology. 12: 159-67. PMID 18249198 DOI: 10.1016/J.Cbpa.2007.12.009  0.374
2008 Kawakami T, Murakami H, Suga H. Messenger RNA-programmed incorporation of multiple N-methyl-amino acids into linear and cyclic peptides. Chemistry & Biology. 15: 32-42. PMID 18215771 DOI: 10.1016/J.Chembiol.2007.12.008  0.387
2008 Goto Y, Ohta A, Sako Y, Yamagishi Y, Murakami H, Suga H. Reprogramming the translation initiation for the synthesis of physiologically stable cyclic peptides. Acs Chemical Biology. 3: 120-9. PMID 18215017 DOI: 10.1021/Cb700233T  0.392
2007 Ohta A, Murakami H, Higashimura E, Suga H. Synthesis of polyester by means of genetic code reprogramming. Chemistry & Biology. 14: 1315-22. PMID 18096500 DOI: 10.1016/J.Chembiol.2007.10.015  0.307
2007 Ohuchi M, Murakami H, Suga H. The flexizyme system: a highly flexible tRNA aminoacylation tool for the translation apparatus. Current Opinion in Chemical Biology. 11: 537-42. PMID 17884697 DOI: 10.1016/J.Cbpa.2007.08.011  0.345
2007 Kang TJ, Suga H. In vitro selection of a 5'-purine ribonucleotide transferase ribozyme. Nucleic Acids Research. 35: 4186-94. PMID 17567602 DOI: 10.1093/Nar/Gkm438  0.331
2007 Kim J, Kang Y, Choi O, Jeong Y, Jeong JE, Lim JY, Kim M, Moon JS, Suga H, Hwang I. Regulation of polar flagellum genes is mediated by quorum sensing and FlhDC in Burkholderia glumae. Molecular Microbiology. 64: 165-79. PMID 17376080 DOI: 10.1111/J.1365-2958.2007.05646.X  0.314
2006 Taki M, Kuno A, Matoba S, Kobayashi Y, Futami J, Murakami H, Suga H, Taira K, Hasegawa T, Sisido M. Leucyl/Phenylalanyl-tRNA-protein transferase-mediated chemoenzymatic coupling of N-terminal Arg/Lys units in post-translationally processed proteins with non-natural amino acids. Chembiochem : a European Journal of Chemical Biology. 7: 1676-9. PMID 16977663 DOI: 10.1002/Cbic.200600181  0.322
2006 Murakami H, Ohta A, Ashigai H, Suga H. A highly flexible tRNA acylation method for non-natural polypeptide synthesis. Nature Methods. 3: 357-9. PMID 16628205 DOI: 10.1038/Nmeth877  0.365
2006 Jog GJ, Igarashi J, Suga H. Stereoisomers of P. aeruginosa autoinducer analog to probe the regulator binding site. Chemistry & Biology. 13: 123-8. PMID 16492560 DOI: 10.1016/J.Chembiol.2005.12.013  0.749
2005 Khan SR, Mavrodi DV, Jog GJ, Suga H, Thomashow LS, Farrand SK. Activation of the phz operon of Pseudomonas fluorescens 2-79 requires the LuxR homolog PhzR, N-(3-OH-Hexanoyl)-L-homoserine lactone produced by the LuxI homolog PhzI, and a cis-acting phz box. Journal of Bacteriology. 187: 6517-27. PMID 16159785 DOI: 10.1128/Jb.187.18.6517-6527.2005  0.741
2005 Kourouklis D, Murakami H, Suga H. Programmable ribozymes for mischarging tRNA with nonnatural amino acids and their applications to translation. Methods (San Diego, Calif.). 36: 239-44. PMID 16076449 DOI: 10.1016/J.Ymeth.2005.04.001  0.312
2004 Kim J, Kim JG, Kang Y, Jang JY, Jog GJ, Lim JY, Kim S, Suga H, Nagamatsu T, Hwang I. Quorum sensing and the LysR-type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae. Molecular Microbiology. 54: 921-34. PMID 15522077 DOI: 10.1111/J.1365-2958.2004.04338.X  0.735
2004 Ramaswamy K, Saito H, Murakami H, Shiba K, Suga H. Designer ribozymes: programming the tRNA specificity into flexizyme. Journal of the American Chemical Society. 126: 11454-5. PMID 15366888 DOI: 10.1021/Ja046843Y  0.558
2004 Tsukiji S, Pattnaik SB, Suga H. Reduction of an aldehyde by a NADH/Zn2+ -dependent redox active ribozyme. Journal of the American Chemical Society. 126: 5044-5. PMID 15099068 DOI: 10.1021/Ja0495213  0.618
2004 Tsukiji S, Ramaswamy K, Suga H. Ribozymes that use redox cofactors Pure and Applied Chemistry. 76: 1525-1536. DOI: 10.1351/Pac200476071525  0.707
2003 Murakami H, Kourouklis D, Suga H. Using a solid-phase ribozyme aminoacylation system to reprogram the genetic code. Chemistry & Biology. 10: 1077-84. PMID 14652075 DOI: 10.1016/J.Chembiol.2003.10.010  0.364
2003 Suga H, Smith KM. Molecular mechanisms of bacterial quorum sensing as a new drug target. Current Opinion in Chemical Biology. 7: 586-91. PMID 14580562 DOI: 10.1016/J.Cbpa.2003.08.001  0.525
2003 Tsukiji S, Pattnaik SB, Suga H. An alcohol dehydrogenase ribozyme. Nature Structural Biology. 10: 713-7. PMID 12910259 DOI: 10.1038/Nsb964  0.616
2003 Murakami H, Saito H, Suga H. A Versatile tRNA Aminoacylation Catalyst Based on RNA Chemistry & Biology. 10: 655-662. PMID 12890539 DOI: 10.1016/S1074-5521(03)00145-5  0.368
2003 Smith KM, Bu Y, Suga H. Library screening for synthetic agonists and antagonists of a Pseudomonas aeruginosa autoinducer. Chemistry & Biology. 10: 563-71. PMID 12837389 DOI: 10.1016/S1074-5521(03)00107-8  0.679
2003 Smith KM, Bu Y, Suga H. Induction and inhibition of Pseudomonas aeruginosa quorum sensing by synthetic autoinducer analogs. Chemistry & Biology. 10: 81-9. PMID 12573701 DOI: 10.1016/S1074-5521(03)00002-4  0.695
2002 Bessho Y, Hodgson DR, Suga H. A tRNA aminoacylation system for non-natural amino acids based on a programmable ribozyme. Nature Biotechnology. 20: 723-8. PMID 12089559 DOI: 10.1038/Nbt0702-723  0.357
2002 Ming X, Smith K, Suga H, Hou YM. Recognition of tRNA backbone for aminoacylation with cysteine: evolution from Escherichia coli to human. Journal of Molecular Biology. 318: 1207-20. PMID 12083512 DOI: 10.1016/S0022-2836(02)00232-2  0.552
2002 Murakami H, Bonzagni NJ, Suga H. Aminoacyl-tRNA synthesis by a resin-immobilized ribozyme. Journal of the American Chemical Society. 124: 6834-5. PMID 12059198 DOI: 10.1021/Ja025872A  0.772
2002 Ramaswamy K, Wei K, Suga H. Minihelix-loop RNAs: minimal structures for aminoacylation catalysts. Nucleic Acids Research. 30: 2162-71. PMID 12000836 DOI: 10.1093/Nar/30.10.2162  0.579
2001 Lee N, Suga H. Essential roles of innersphere metal ions for the formation of the glutamine binding site in a bifunctional ribozyme. Biochemistry. 40: 13633-43. PMID 11695912 DOI: 10.1021/Bi011103C  0.552
2001 Flynn-Charlebois A, Lee N, Suga H. A single metal ion plays structural and chemical roles in an aminoacyl-transferase ribozyme. Biochemistry. 40: 13623-32. PMID 11695911 DOI: 10.1021/Bi011102K  0.57
2001 Lee N, Suga H. A minihelix-loop RNA acts as a trans-aminoacylation catalyst. Rna (New York, N.Y.). 7: 1043-51. PMID 11453065 DOI: 10.1017/S1355838201010457  0.58
2001 Saito H, Kourouklis D, Suga H. An in vitro evolved precursor tRNA with aminoacylation activity Embo Journal. 20: 1797-1806. PMID 11285242 DOI: 10.1093/Emboj/20.7.1797  0.342
2000 Lee N, Bessho Y, Wei K, Szostak JW, Suga H. Ribozyme-catalyzed tRNA aminoacylation. Nature Structural Biology. 7: 28-33. PMID 10625423 DOI: 10.1038/71225  0.673
1998 Suga H, Lohse PA, Szostak JW. Structural and kinetic characterization of an acyl transferase ribozyme. Journal of the American Chemical Society. 120: 1151-6. PMID 11541113 DOI: 10.1021/Ja972472S  0.543
1998 Suga H, Cowan JA, Szostak JW. Unusual metal ion catalysis in an acyl-transferase ribozyme. Biochemistry. 37: 10118-25. PMID 9665717 DOI: 10.1021/Bi980432A  0.483
1995 Tsumuraya T, Suga H, Meguro S, Tsunakawa A, Masamune S. Catalytic antibodies generated via homologous and heterologous immunization Journal of the American Chemical Society. 117: 11390-11396. DOI: 10.1021/Ja00151A002  0.496
1994 Suga H, Tanimoto N, Sinskey AJ, Masamune S. Glycosidase antibodies induced to a half-chair transition-state analog Journal of the American Chemical Society. 116: 11197-11198. DOI: 10.1021/Ja00103A061  0.477
1994 Suga H, Ersoy O, Williams SF, Tsumuraya T, Margolies MN, Sinskey AJ, Masamune S. Catalytic antibodies generated via heterologous immunization. [Erratum to document cited in CA121:80587] Journal of the American Chemical Society. 116: 8432-8432. DOI: 10.1021/Ja00097A087  0.489
1994 Suga H, Ersoy O, Williams SF, Tsumuraya T, Margolies MN, Sinskey AJ, Masamune S. Catalytic antibodies generated via heterologous immunization Journal of the American Chemical Society. 116: 6025-6026. DOI: 10.1021/Ja00092A086  0.617
1994 Suga H, Ersoy O, Tsumuraya T, Lee J, Sinskey AJ, Masamune S. Esterolytic antibodies induced to haptens with a 1,2-amino alcohol functionality Journal of the American Chemical Society. 116: 487-494. DOI: 10.1021/Ja00081A008  0.643
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