Hiroaki Suga - Publications

Affiliations: 
State University of New York, Buffalo, Buffalo, NY, United States 
Area:
Organic Chemistry, Biochemistry

125 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Vinogradov AA, Nagai E, Chang JS, Narumi K, Onaka H, Goto Y, Suga H. Accurate Broadcasting of Substrate Fitness for Lactazole Biosynthetic Pathway from Reactivity-Profiling mRNA Display. Journal of the American Chemical Society. PMID 33211968 DOI: 10.1021/jacs.0c10374  0.36
2020 Vargas-Rodriguez O, Bakhtina M, McGowan D, Abid J, Goto Y, Suga H, Musier-Forsyth K. Human -editing enzyme displays tRNA acceptor stem specificity and relaxed amino acid selectivity. The Journal of Biological Chemistry. PMID 33051185 DOI: 10.1074/jbc.RA120.015981  0.36
2020 Vinogradov AA, Shimomura M, Kano N, Goto Y, Onaka H, Suga H. Promiscuous enzymes cooperate at the substrate level en route to lactazole A. Journal of the American Chemical Society. PMID 32664727 DOI: 10.1021/jacs.0c05541  0.36
2020 Okuma R, Kuwahara T, Yoshikane T, Watanabe M, Dranchak P, Inglese J, Shuto S, Goto Y, Suga H. A macrocyclic peptide library with a structurally constrained cyclopropane-containing building block leads to thiol-independent inhibitors of phosphoglycerate mutase. Chemistry, An Asian Journal. PMID 32633882 DOI: 10.1002/asia.202000700  0.36
2020 Vinogradov AA, Shimomura M, Goto Y, Ozaki T, Asamizu S, Sugai Y, Suga H, Onaka H. Minimal lactazole scaffold for in vitro thiopeptide bioengineering. Nature Communications. 11: 2272. PMID 32385237 DOI: 10.1038/s41467-020-16145-4  0.36
2020 Fleming SR, Himes PM, Ghodge SV, Goto Y, Suga H, Bowers AA. Exploring the Post-Translational Enzymology of PaaA by mRNA Display. Journal of the American Chemical Society. PMID 32109054 DOI: 10.1021/jacs.0c01576  0.36
2020 Sakurai Y, Mizumura W, Ito K, Iwasaki K, Katoh T, Goto Y, Suga H, Harashima H. Improved stability of siRNA-loaded lipid nanoparticles prepared with a PEG-monoacyl fatty acid facilitates ligand-mediated siRNA delivery. Molecular Pharmaceutics. PMID 32091909 DOI: 10.1021/acs.molpharmaceut.0c00087  0.36
2019 Maini R, Kimura H, Takatsuji R, Katoh T, Goto Y, Suga H. Ribosomal Formation of Thioamide Bond in Polypeptide Synthesis. Journal of the American Chemical Society. PMID 31815469 DOI: 10.1021/jacs.9b11097  0.36
2019 Kato Y, Kuroda T, Huang Y, Ohta R, Goto Y, Suga H. Chemoenzymatic posttranslational modification reactions for the synthesis of Ψ[CH2NH]-containing peptides. Angewandte Chemie (International Ed. in English). PMID 31622000 DOI: 10.1002/anie.201910894  0.36
2019 Goto Y, Suga H. In vitro biosynthesis of peptides containing exotic azoline analogs. Chembiochem : a European Journal of Chemical Biology. PMID 31523895 DOI: 10.1002/cbic.201900521  0.36
2019 Tran STP, Hipolito CJ, Suzuki H, Xie R, Kim Tuyen HD, Dijke PT, Terasaka N, Goto Y, Suga H, Kato M. Generation of non-standard macrocyclic peptides specifically binding TSC-22 homologous gene-1. Biochemical and Biophysical Research Communications. PMID 31227214 DOI: 10.1016/j.bbrc.2019.06.035  0.36
2019 Fujino T, Kondo T, Suga H, Murakami H. Exploring of minimal RNA substrate of flexizymes. Chembiochem : a European Journal of Chemical Biology. PMID 30950544 DOI: 10.1002/cbic.201900150  0.44
2019 Takatsuji R, Shinbara K, Katoh T, Goto Y, Passioura T, Yajima R, Komatsu Y, Suga H. Ribosomal synthesis of backbone-cyclic peptides compatible with in vitro display. Journal of the American Chemical Society. PMID 30648857 DOI: 10.1021/jacs.8b05327  0.36
2019 Fleming SR, Bartges TE, Vinogradov AA, Kirkpatrick CL, Goto Y, Suga H, Hicks LM, Bowers AA. Flexizyme-enabled benchtop biosynthesis of thiopeptides. Journal of the American Chemical Society. PMID 30602112 DOI: 10.1021/jacs.8b11521  0.36
2018 Goto Y, Suga H. Engineering of RiPP pathways for the production of artificial peptides bearing various non-proteinogenic structures. Current Opinion in Chemical Biology. 46: 82-90. PMID 29957445 DOI: 10.1016/j.cbpa.2018.06.014  0.36
2018 Iwane Y, Katoh T, Goto Y, Suga H. Artificial Division of Codon Boxes for Expansion of the Amino Acid Repertoire of Ribosomal Polypeptide Synthesis. Methods in Molecular Biology (Clifton, N.J.). 1728: 17-47. PMID 29404989 DOI: 10.1007/978-1-4939-7574-7_2  0.36
2017 Sakurai Y, Mizumura W, Murata M, Hada T, Yamamoto S, Ito K, Iwasaki K, Katoh T, Goto Y, Takagi A, Kohara M, Suga H, Harashima H. Efficient siRNA delivery by lipid nanoparticles modified with a non-standard macrocyclic peptide for EpCAM-targeting. Molecular Pharmaceutics. PMID 28789523 DOI: 10.1021/acs.molpharmaceut.7b00362  0.36
2017 Danhart EM, Bakhtina M, Cantara WA, Kuzmishin AB, Ma X, Sanford BL, Košutić M, Goto Y, Suga H, Nakanishi K, Micura R, Foster MP, Musier-Forsyth K. Conformational and chemical selection by a trans-acting editing domain. Proceedings of the National Academy of Sciences of the United States of America. PMID 28768811 DOI: 10.1073/pnas.1703925114  0.36
2017 Bacusmo JM, Kuzmishin AB, Cantara WA, Goto Y, Suga H, Musier-Forsyth K. Quality control by trans-editing factor prevents global mistranslation of non-protein amino acid α-aminobutyrate. Rna Biology. 0. PMID 28737471 DOI: 10.1080/15476286.2017.1353846  0.36
2017 Amoh T, Murakami K, Kariyama R, Hori K, Viducic D, Hirota K, Igarashi J, Suga H, Parsek MR, Kumon H, Miyake Y. Effects of an autoinducer analogue on antibiotic tolerance in Pseudomonas aeruginosa. The Journal of Antimicrobial Chemotherapy. PMID 28510695 DOI: 10.1093/jac/dkx132  0.6
2017 Kawamura A, Münzel M, Kojima T, Yapp C, Bhushan B, Goto Y, Tumber A, Katoh T, King ON, Passioura T, Walport LJ, Hatch SB, Madden S, Müller S, Brennan PE, ... ... Suga H, et al. Highly selective inhibition of histone demethylases by de novo macrocyclic peptides. Nature Communications. 8: 14773. PMID 28382930 DOI: 10.1038/ncomms14773  0.36
2017 Amoh T, Murakami K, Kariyama R, Hori K, Irie Y, Viducic D, Hirota K, Igarashi J, Suga H, Kumon H, Miyake Y. A Pseudomonas aeruginosa Quorum-Sensing autoinducer analog enhances the activity of antibiotics against resistant strains. The Journal of Medical Investigation : Jmi. 64: 101-109. PMID 28373605 DOI: 10.2152/jmi.64.101  0.6
2017 Ozaki T, Yamashita K, Goto Y, Shimomura M, Hayashi S, Asamizu S, Sugai Y, Ikeda H, Suga H, Onaka H. Dissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivo. Nature Communications. 8: 14207. PMID 28165449 DOI: 10.1038/ncomms14207  0.36
2016 Lee KB, Hou CY, Kim CE, Kim DM, Suga H, Kang TJ. Genetic Code Expansion by Degeneracy Reprogramming of Arginyl Codons. Chembiochem : a European Journal of Chemical Biology. PMID 27151886 DOI: 10.1002/cbic.201600111  0.96
2016 Iwane Y, Hitomi A, Murakami H, Katoh T, Goto Y, Suga H. Expanding the amino acid repertoire of ribosomal polypeptide synthesis via the artificial division of codon boxes. Nature Chemistry. 8: 317-25. PMID 27001726 DOI: 10.1038/nchem.2446  0.44
2016 Fujino T, Goto Y, Suga H, Murakami H. Ribosomal Synthesis of Peptides with Multiple β-Amino Acids. Journal of the American Chemical Society. PMID 26807980 DOI: 10.1021/jacs.5b12482  0.44
2015 Bayó-Puxan N, Rodríguez-Mias R, Goldflam M, Kotev M, Ciudad S, Hipolito CJ, Varese M, Suga H, Campos-Olivas R, Barril X, Guallar V, Teixidó M, García J, Giralt E. Combined Use of Oligopeptides, Fragment Libraries, and Natural Compounds: A Comprehensive Approach To Sample the Druggability of Vascular Endothelial Growth Factor. Chemmedchem. PMID 26553526 DOI: 10.1002/cmdc.201500467  0.96
2015 Iwasaki K, Goto Y, Katoh T, Yamashita T, Kaneko S, Suga H. A Fluorescent Imaging Probe Based on a Macrocyclic Scaffold That Binds to Cellular EpCAM. Journal of Molecular Evolution. PMID 26553371 DOI: 10.1007/s00239-015-9710-z  0.96
2015 Rogers JM, Suga H. Discovering functional, non-proteinogenic amino acid containing, peptides using genetic code reprogramming. Organic & Biomolecular Chemistry. 13: 9353-63. PMID 26280393 DOI: 10.1039/c5ob01336d  0.96
2015 Liu Z, Vargas-Rodriguez O, Goto Y, Novoa EM, Ribas de Pouplana L, Suga H, Musier-Forsyth K. Homologous trans-editing factors with broad tRNA specificity prevent mistranslation caused by serine/threonine misactivation. Proceedings of the National Academy of Sciences of the United States of America. 112: 6027-32. PMID 25918376 DOI: 10.1073/pnas.1423664112  0.96
2015 Terasaka N, Iwane Y, Geiermann AS, Goto Y, Suga H. Recent developments of engineered translational machineries for the incorporation of non-canonical amino acids into polypeptides. International Journal of Molecular Sciences. 16: 6513-31. PMID 25803109 DOI: 10.3390/ijms16036513  0.96
2015 Ito K, Sakai K, Suzuki Y, Ozawa N, Hatta T, Natsume T, Matsumoto K, Suga H. Artificial human Met agonists based on macrocycle scaffolds. Nature Communications. 6: 6373. PMID 25758345 DOI: 10.1038/ncomms7373  0.96
2015 Novoa EM, Vargas-Rodriguez O, Lange S, Goto Y, Suga H, Musier-Forsyth K, Ribas de Pouplana L. Ancestral AlaX editing enzymes for control of genetic code fidelity are not tRNA-specific. The Journal of Biological Chemistry. 290: 10495-503. PMID 25724653 DOI: 10.1074/jbc.M115.640060  0.96
2015 Morioka T, Loik ND, Hipolito CJ, Goto Y, Suga H. Selection-based discovery of macrocyclic peptides for the next generation therapeutics. Current Opinion in Chemical Biology. 26: 34-41. PMID 25703142 DOI: 10.1016/j.cbpa.2015.01.023  0.96
2015 Bashiruddin NK, Suga H. Construction and screening of vast libraries of natural product-like macrocyclic peptides using in vitro display technologies. Current Opinion in Chemical Biology. 24: 131-8. PMID 25483262 DOI: 10.1016/j.cbpa.2014.11.011  0.96
2014 Torikai K, Suga H. Ribosomal synthesis of an amphotericin-B inspired macrocycle. Journal of the American Chemical Society. 136: 17359-61. PMID 25454254 DOI: 10.1021/ja508648s  0.96
2014 Desai BJ, Goto Y, Cembran A, Fedorov AA, Almo SC, Gao J, Suga H, Gerlt JA. Investigating the role of a backbone to substrate hydrogen bond in OMP decarboxylase using a site-specific amide to ester substitution. Proceedings of the National Academy of Sciences of the United States of America. 111: 15066-71. PMID 25275007 DOI: 10.1073/pnas.1411772111  0.96
2014 Passioura T, Suga H. Reprogramming the genetic code in vitro. Trends in Biochemical Sciences. 39: 400-8. PMID 25129886 DOI: 10.1016/j.tibs.2014.07.005  0.96
2014 Adachi S, Homoto M, Tanaka R, Hioki Y, Murakami H, Suga H, Matsumoto M, Nakayama KI, Hatta T, Iemura S, Natsume T. ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK-RSK pathway. Nucleic Acids Research. 42: 10037-49. PMID 25106868 DOI: 10.1093/nar/gku652  0.44
2014 Goto Y, Ito Y, Kato Y, Tsunoda S, Suga H. One-pot synthesis of azoline-containing peptides in a cell-free translation system integrated with a posttranslational cyclodehydratase. Chemistry & Biology. 21: 766-74. PMID 24856821 DOI: 10.1016/j.chembiol.2014.04.008  0.96
2014 Shimada T, Shimada K, Matsui M, Kitai Y, Igarashi J, Suga H, Ishihama A. Roles of cell division control factor SdiA: recognition of quorum sensing signals and modulation of transcription regulation targets. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 19: 405-18. PMID 24645791 DOI: 10.1111/gtc.12139  0.6
2014 Passioura T, Katoh T, Goto Y, Suga H. Selection-based discovery of druglike macrocyclic peptides. Annual Review of Biochemistry. 83: 727-52. PMID 24580641 DOI: 10.1146/annurev-biochem-060713-035456  0.36
2014 Yamagata K, Goto Y, Nishimasu H, Morimoto J, Ishitani R, Dohmae N, Takeda N, Nagai R, Komuro I, Suga H, Nureki O. Structural basis for potent inhibition of SIRT2 deacetylase by a macrocyclic peptide inducing dynamic structural change. Structure (London, England : 1993). 22: 345-52. PMID 24389023 DOI: 10.1016/j.str.2013.12.001  0.36
2014 Das M, Vargas-Rodriguez O, Goto Y, Suga H, Musier-Forsyth K. Distinct tRNA recognition strategies used by a homologous family of editing domains prevent mistranslation. Nucleic Acids Research. 42: 3943-53. PMID 24371276 DOI: 10.1093/nar/gkt1332  0.96
2014 Passioura T, Suga H. Flexizymes, their evolutionary history and diverse utilities. Topics in Current Chemistry. 344: 331-45. PMID 23478876 DOI: 10.1007/128_2013_421  0.96
2014 Terasaka N, Suga H. Flexizymes-facilitated genetic code reprogramming leading to the discovery of drug-like peptides Chemistry Letters. 43: 11-19. DOI: 10.1246/cl.130910  0.96
2013 Goto Y, Iseki M, Hitomi A, Murakami H, Suga H. Nonstandard peptide expression under the genetic code consisting of reprogrammed dual sense codons. Acs Chemical Biology. 8: 2630-4. PMID 24099623 DOI: 10.1021/cb400549p  0.44
2013 Passioura T, Suga H. Flexizyme-mediated genetic reprogramming as a tool for noncanonical peptide synthesis and drug discovery. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 6530-6. PMID 23519693 DOI: 10.1002/chem.201300247  0.96
2013 Kawakami T, Ishizawa T, Fujino T, Reid PC, Suga H, Murakami H. In vitro selection of multiple libraries created by genetic code reprogramming to discover macrocyclic peptides that antagonize VEGFR2 activity in living cells. Acs Chemical Biology. 8: 1205-14. PMID 23517428 DOI: 10.1021/cb300697h  0.96
2013 Fujino T, Goto Y, Suga H, Murakami H. Reevaluation of the D-amino acid compatibility with the elongation event in translation. Journal of the American Chemical Society. 135: 1830-7. PMID 23301668 DOI: 10.1021/ja309570x  0.44
2012 Chai H, Hazawa M, Hosokawa Y, Igarashi J, Suga H, Kashiwakura I. Novel acridine-based N-acyl-homoserine lactone analogs induce endoreduplication in the human oral squamous carcinoma cell line SAS. Biological & Pharmaceutical Bulletin. 35: 1257-63. PMID 22863922 DOI: DN/JST.JSTAGE/bpb/b12-00033  0.6
2012 Iwasaki K, Goto Y, Katoh T, Suga H. Selective thioether macrocyclization of peptides having the N-terminal 2-chloroacetyl group and competing two or three cysteine residues in translation. Organic & Biomolecular Chemistry. 10: 5783-6. PMID 22419118 DOI: 10.1039/c2ob25306b  0.36
2012 Hipolito CJ, Suga H. Ribosomal production and in vitro selection of natural product-like peptidomimetics: the FIT and RaPID systems. Current Opinion in Chemical Biology. 16: 196-203. PMID 22401851 DOI: 10.1016/j.cbpa.2012.02.014  0.96
2012 Goto Y, Suga H. Flexizymes as a tRNA acylation tool facilitating genetic code reprogramming. Methods in Molecular Biology (Clifton, N.J.). 848: 465-78. PMID 22315087 DOI: 10.1007/978-1-61779-545-9_29  0.96
2012 Reid PC, Goto Y, Katoh T, Suga H. Charging of tRNAs using ribozymes and selection of cyclic peptides containing thioethers. Methods in Molecular Biology (Clifton, N.J.). 805: 335-48. PMID 22094815 DOI: 10.1007/978-1-61779-379-0_19  0.36
2012 Hazawa M, Kudo M, Iwata T, Saito K, Takahashi K, Igarashi J, Suga H, Kashiwakura I. Caspase-independent apoptosis induction of quorum-sensing autoinducer analogs against chronic myeloid leukemia K562. Investigational New Drugs. 30: 862-9. PMID 21207239 DOI: 10.1007/s10637-010-9623-z  0.6
2012 Chai H, Hazawa M, Shirai N, Igarashi J, Takahashi K, Hosokawa Y, Suga H, Kashiwakura I. Functional properties of synthetic N-acyl-L-homoserine lactone analogs of quorum-sensing gram-negative bacteria on the growth of human oral squamous carcinoma cells. Investigational New Drugs. 30: 157-63. PMID 20878204 DOI: 10.1007/s10637-010-9544-x  0.6
2011 Yamagishi Y, Shoji I, Miyagawa S, Kawakami T, Katoh T, Goto Y, Suga H. Natural product-like macrocyclic N-methyl-peptide inhibitors against a ubiquitin ligase uncovered from a ribosome-expressed de novo library. Chemistry & Biology. 18: 1562-70. PMID 22195558 DOI: 10.1016/j.chembiol.2011.09.013  0.96
2011 Suga H, Futai K, Jin K. Metal ion requirements in artificial ribozymes that catalyze aminoacylation and redox reactions. Metal Ions in Life Sciences. 9: 277-97. PMID 22010276  0.96
2011 Katoh T, Goto Y, Reza MS, Suga H. Ribosomal synthesis of backbone macrocyclic peptides. Chemical Communications (Cambridge, England). 47: 9946-58. PMID 21766105 DOI: 10.1039/c1cc12647d  0.36
2011 Chung J, Goo E, Yu S, Choi O, Lee J, Kim J, Kim H, Igarashi J, Suga H, Moon JS, Hwang I, Rhee S. Small-molecule inhibitor binding to an N-acyl-homoserine lactone synthase. Proceedings of the National Academy of Sciences of the United States of America. 108: 12089-94. PMID 21730159 DOI: 10.1073/pnas.1103165108  0.6
2011 Morimoto J, Hayashi Y, Iwasaki K, Suga H. Flexizymes: their evolutionary history and the origin of catalytic function. Accounts of Chemical Research. 44: 1359-68. PMID 21711008 DOI: 10.1021/ar2000953  0.36
2011 Goto Y, Katoh T, Suga H. Flexizymes for genetic code reprogramming. Nature Protocols. 6: 779-90. PMID 21637198 DOI: 10.1038/nprot.2011.331  0.36
2011 Kang TJ, Suga H. Translation of a histone H3 tail as a model system for studying peptidyl-tRNA drop-off. Febs Letters. 585: 2269-74. PMID 21627973 DOI: 10.1016/j.febslet.2011.05.051  0.96
2011 Öjemalm K, Higuchi T, Jiang Y, Langel Ü, Nilsson I, White SH, Suga H, von Heijne G. Apolar surface area determines the efficiency of translocon-mediated membrane-protein integration into the endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America. 108: E359-64. PMID 21606334 DOI: 10.1073/pnas.1100120108  0.96
2011 Ohshiro Y, Nakajima E, Goto Y, Fuse S, Takahashi T, Doi T, Suga H. Ribosomal synthesis of backbone-macrocyclic peptides containing γ-amino acids. Chembiochem : a European Journal of Chemical Biology. 12: 1183-7. PMID 21506233 DOI: 10.1002/cbic.201100104  0.36
2011 Igarashi J, Suga H. Custom synthesis of autoinducers and their analogues. Methods in Molecular Biology (Clifton, N.J.). 692: 265-74. PMID 21031318 DOI: 10.1007/978-1-60761-971-0_19  0.96
2010 Hayashi G, Goto Y, Suga H. Ribosome evolution for two artificial amino acids in E. coli. Chemistry & Biology. 17: 320-1. PMID 20416503 DOI: 10.1016/j.chembiol.2010.04.005  0.36
2009 Kawakami T, Ohta A, Ohuchi M, Ashigai H, Murakami H, Suga H. Diverse backbone-cyclized peptides via codon reprogramming. Nature Chemical Biology. 5: 888-90. PMID 19915537 DOI: 10.1038/nchembio.259  0.44
2009 Goto Y, Iwasaki K, Torikai K, Murakami H, Suga H. Ribosomal synthesis of dehydrobutyrine- and methyllanthionine-containing peptides. Chemical Communications (Cambridge, England). 3419-21. PMID 19503890 DOI: 10.1039/b904314d  0.96
2009 Yamagishi Y, Ashigai H, Goto Y, Murakami H, Suga H. Ribosomal synthesis of cyclic peptides with a fluorogenic oxidative coupling reaction. Chembiochem : a European Journal of Chemical Biology. 10: 1469-72. PMID 19472249 DOI: 10.1002/cbic.200900021  0.44
2009 Nakajima E, Goto Y, Sako Y, Murakami H, Suga H. Ribosomal synthesis of peptides with C-terminal lactams, thiolactones, and alkylamides. Chembiochem : a European Journal of Chemical Biology. 10: 1186-92. PMID 19370739 DOI: 10.1002/cbic.200900058  0.44
2009 Niwa N, Yamagishi Y, Murakami H, Suga H. A flexizyme that selectively charges amino acids activated by a water-friendly leaving group. Bioorganic & Medicinal Chemistry Letters. 19: 3892-4. PMID 19364647 DOI: 10.1016/j.bmcl.2009.03.114  0.44
2009 Murakami H, Ohta A, Suga H. Bases in the anticodon loop of tRNA(Ala)(GGC) prevent misreading. Nature Structural & Molecular Biology. 16: 353-8. PMID 19305404 DOI: 10.1038/nsmb.1580  0.44
2009 Goto Y, Suga H. Translation initiation with initiator tRNA charged with exotic peptides. Journal of the American Chemical Society. 131: 5040-1. PMID 19301866 DOI: 10.1021/ja900597d  0.96
2008 Kawakami T, Murakami H, Suga H. Ribosomal synthesis of polypeptoids and peptoid-peptide hybrids. Journal of the American Chemical Society. 130: 16861-3. PMID 19053417 DOI: 10.1021/ja806998v  0.44
2008 Ohta A, Murakami H, Suga H. Polymerization of alpha-hydroxy acids by ribosomes. Chembiochem : a European Journal of Chemical Biology. 9: 2773-8. PMID 18985645 DOI: 10.1002/cbic.200800439  0.44
2008 Xiao H, Murakami H, Suga H, Ferré-D'Amaré AR. Structural basis of specific tRNA aminoacylation by a small in vitro selected ribozyme. Nature. 454: 358-61. PMID 18548004 DOI: 10.1038/nature07033  0.44
2008 Goto Y, Murakami H, Suga H. Initiating translation with D-amino acids. Rna (New York, N.Y.). 14: 1390-8. PMID 18515548 DOI: 10.1261/rna.1020708  0.44
2008 Sako Y, Morimoto J, Murakami H, Suga H. Ribosomal synthesis of bicyclic peptides via two orthogonal inter-side-chain reactions. Journal of the American Chemical Society. 130: 7232-4. PMID 18479111 DOI: 10.1021/ja800953c  0.44
2008 Kang TJ, Suga H. Ribosomal synthesis of nonstandard peptides. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 86: 92-9. PMID 18443622 DOI: 10.1139/O08-009  0.96
2008 Sako Y, Goto Y, Murakami H, Suga H. Ribosomal synthesis of peptidase-resistant peptides closed by a nonreducible inter-side-chain bond. Acs Chemical Biology. 3: 241-9. PMID 18338852 DOI: 10.1021/cb800010p  0.44
2008 Kawakami T, Murakami H, Suga H. Messenger RNA-programmed incorporation of multiple N-methyl-amino acids into linear and cyclic peptides. Chemistry & Biology. 15: 32-42. PMID 18215771 DOI: 10.1016/j.chembiol.2007.12.008  0.44
2008 Goto Y, Ohta A, Sako Y, Yamagishi Y, Murakami H, Suga H. Reprogramming the translation initiation for the synthesis of physiologically stable cyclic peptides. Acs Chemical Biology. 3: 120-9. PMID 18215017 DOI: 10.1021/cb700233t  0.44
2007 Ohta A, Murakami H, Higashimura E, Suga H. Synthesis of polyester by means of genetic code reprogramming. Chemistry & Biology. 14: 1315-22. PMID 18096500 DOI: 10.1016/j.chembiol.2007.10.015  0.44
2007 Sako Y, Murakami H, Suga H. [Reprogramming the genetic code using flexizyme]. Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. 52: 1643-8. PMID 18051393  0.44
2007 Pattnaik SB, Suga H. Re-engineering an in-vitro evolved ribozyme. Nucleic Acids Symposium Series (2004). 381-2. PMID 18029746 DOI: 10.1093/nass/nrm191  0.96
2007 Kang TJ, Suga H. In vitro selection of a 5'-purine nucleotide transferase ribozyme. Nucleic Acids Symposium Series (2004). 379-80. PMID 18029745 DOI: 10.1093/nass/nrm190  0.96
2007 Kawakami T, Murakami H, Suga H. Exploration of incorporation of Nalpha-methylated amino acids into peptides by sense-suppression method. Nucleic Acids Symposium Series (2004). 361-2. PMID 18029736 DOI: 10.1093/nass/nrm181  0.96
2007 Ohuchi M, Murakami H, Suga H. In situ generation of aminoacyl-tRNAs assisted by ribozymes in translation apparatus. Nucleic Acids Symposium Series (2004). 115-6. PMID 18029613 DOI: 10.1093/nass/nrm058  0.44
2007 Khan SR, Herman J, Krank J, Serkova NJ, Churchill ME, Suga H, Farrand SK. N-(3-hydroxyhexanoyl)-l-homoserine lactone is the biologically relevant quormone that regulates the phz operon of Pseudomonas chlororaphis strain 30-84. Applied and Environmental Microbiology. 73: 7443-55. PMID 17921283 DOI: 10.1128/AEM.01354-07  0.96
2007 Ohuchi M, Murakami H, Suga H. The flexizyme system: a highly flexible tRNA aminoacylation tool for the translation apparatus. Current Opinion in Chemical Biology. 11: 537-42. PMID 17884697 DOI: 10.1016/j.cbpa.2007.08.011  0.44
2007 Kang TJ, Suga H. In vitro selection of a 5'-purine ribonucleotide transferase ribozyme. Nucleic Acids Research. 35: 4186-94. PMID 17567602 DOI: 10.1093/nar/gkm438  0.96
2007 Chan YY, Bian HS, Tan TM, Mattmann ME, Geske GD, Igarashi J, Hatano T, Suga H, Blackwell HE, Chua KL. Control of quorum sensing by a Burkholderia pseudomallei multidrug efflux pump. Journal of Bacteriology. 189: 4320-4. PMID 17384185 DOI: 10.1128/JB.00003-07  0.96
2006 Murakami H, Suga H. [Expansion and reprogramming of genetic code by Flexizyme]. Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. 51: 2496-501. PMID 17471969  0.96
2006 Ohuchi M, Murakami H, Suga H. In vitro evolution of flexizymes that function under the conditions in translation system. Nucleic Acids Symposium Series (2004). 299-300. PMID 17150936 DOI: 10.1093/nass/nrl149  0.44
2006 Goto Y, Ashigai H, Sako Y, Murakami H, Suga H. Translation initiation by using various N-acylaminoacyl tRNAs. Nucleic Acids Symposium Series (2004). 293-4. PMID 17150933 DOI: 10.1093/nass/nrl146  0.44
2006 Murakami H, Ohta A, Goto Y, Sako Y, Suga H. Flexizyme as a versatile tRNA acylation catalyst and the application for translation. Nucleic Acids Symposium Series (2004). 35-6. PMID 17150804 DOI: 10.1093/nass/nrl018  0.44
2006 Taki M, Kuno A, Matoba S, Kobayashi Y, Futami J, Murakami H, Suga H, Taira K, Hasegawa T, Sisido M. Leucyl/Phenylalanyl-tRNA-protein transferase-mediated chemoenzymatic coupling of N-terminal Arg/Lys units in post-translationally processed proteins with non-natural amino acids. Chembiochem : a European Journal of Chemical Biology. 7: 1676-9. PMID 16977663 DOI: 10.1002/cbic.200600181  0.44
2006 Murakami H, Ohta A, Ashigai H, Suga H. A highly flexible tRNA acylation method for non-natural polypeptide synthesis. Nature Methods. 3: 357-9. PMID 16628205 DOI: 10.1038/nmeth877  0.44
2006 Jog GJ, Igarashi J, Suga H. Stereoisomers of P. aeruginosa autoinducer analog to probe the regulator binding site. Chemistry & Biology. 13: 123-8. PMID 16492560 DOI: 10.1016/j.chembiol.2005.12.013  0.96
2006 Suga H. Ribosomal synthesis of nonnatural biopolymers in microscales Proceedings of 2006 International Conference On Microtechnologies in Medicine and Biology. 9. DOI: 10.1109/MMB.2006.251476  0.96
2005 Khan SR, Mavrodi DV, Jog GJ, Suga H, Thomashow LS, Farrand SK. Activation of the phz operon of Pseudomonas fluorescens 2-79 requires the LuxR homolog PhzR, N-(3-OH-Hexanoyl)-L-homoserine lactone produced by the LuxI homolog PhzI, and a cis-acting phz box. Journal of Bacteriology. 187: 6517-27. PMID 16159785 DOI: 10.1128/JB.187.18.6517-6527.2005  0.96
2005 Kourouklis D, Murakami H, Suga H. Programmable ribozymes for mischarging tRNA with nonnatural amino acids and their applications to translation. Methods (San Diego, Calif.). 36: 239-44. PMID 16076449 DOI: 10.1016/j.ymeth.2005.04.001  0.96
2004 Kim J, Kim JG, Kang Y, Jang JY, Jog GJ, Lim JY, Kim S, Suga H, Nagamatsu T, Hwang I. Quorum sensing and the LysR-type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae. Molecular Microbiology. 54: 921-34. PMID 15522077 DOI: 10.1111/j.1365-2958.2004.04338.x  0.96
2004 Ramaswamy K, Saito H, Murakami H, Shiba K, Suga H. Designer ribozymes: programming the tRNA specificity into flexizyme. Journal of the American Chemical Society. 126: 11454-5. PMID 15366888 DOI: 10.1021/ja046843y  0.6
2004 Hodgson DRW, Suga H. Mechanistic Studies on Acyl-Transferase Ribozymes and Beyond Biopolymers. 73: 130-150. PMID 14691945 DOI: 10.1002/bip.10518  0.96
2003 Suga H, Smith KM. Molecular mechanisms of bacterial quorum sensing as a new drug target. Current Opinion in Chemical Biology. 7: 586-91. PMID 14580562 DOI: 10.1016/j.cbpa.2003.08.001  0.96
2003 Suga H. Quorum sensing in Pseudomonas aeruginosa: cell to-cell communication to sense the cell density of the same species Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. 48: 1609-1615. PMID 12931620  0.96
2003 Murakami H, Suga H. Artificial ribozymes: selection and application for nonnatural amino acid mutagenesis Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. 48: 1511-1518. PMID 12931607  0.96
2003 Smith KM, Bu Y, Suga H. Library screening for synthetic agonists and antagonists of a Pseudomonas aeruginosa autoinducer. Chemistry & Biology. 10: 563-71. PMID 12837389  0.92
2003 Smith KM, Bu Y, Suga H. Induction and inhibition of Pseudomonas aeruginosa quorum sensing by synthetic autoinducer analogs. Chemistry & Biology. 10: 81-9. PMID 12573701  0.92
2002 Saito H, Suga H. Outersphere and innersphere coordinated metal ions in an aminoacyl-tRNA synthetase ribozyme Nucleic Acids Research. 30: 5151-5159. PMID 12466539 DOI: 10.1093/nar/gkf641  0.96
2002 Murakami H, Bonzagni NJ, Suga H. Aminoacyl-tRNA synthesis by a resin-immobilized ribozyme. Journal of the American Chemical Society. 124: 6834-5. PMID 12059198 DOI: 10.1021/ja025872a  0.96
2002 Ramaswamy K, Wei K, Suga H. Minihelix-loop RNAs: minimal structures for aminoacylation catalysts. Nucleic Acids Research. 30: 2162-71. PMID 12000836  0.6
2001 Saito H, Watanabe K, Suga H. Concurrent molecular recognition of the amino acid and tRNA by a ribozyme Rna. 7: 1867-1878. PMID 11780641  0.96
2001 Lee N, Suga H. Essential roles of innersphere metal ions for the formation of the glutamine binding site in a bifunctional ribozyme. Biochemistry. 40: 13633-43. PMID 11695912 DOI: 10.1021/bi011103c  0.96
2001 Flynn-Charlebois A, Lee N, Suga H. A single metal ion plays structural and chemical roles in an aminoacyl-transferase ribozyme. Biochemistry. 40: 13623-32. PMID 11695911  0.96
2001 Saito H, Suga H. A ribozyme exclusively aminoacylates the 3′-hydroxyl group of the tRNA terminal adenosine [10] Journal of the American Chemical Society. 123: 7178-7179. PMID 11459506 DOI: 10.1021/ja015756s  0.96
2001 Lee N, Suga H. A minihelix-loop RNA acts as a trans-aminoacylation catalyst. Rna (New York, N.Y.). 7: 1043-51. PMID 11453065 DOI: 10.1017/S1355838201010457  0.96
2001 Vaidya A, Suga H. Diverse roles of metal ions in acyl-transferase ribozymes Biochemistry. 40: 7200-7210. PMID 11401567  0.96
2000 Lee N, Bessho Y, Wei K, Szostak JW, Suga H. Ribozyme-catalyzed tRNA aminoacylation. Nature Structural Biology. 7: 28-33. PMID 10625423 DOI: 10.1038/71225  0.96
1995 Tsumuraya T, Suga H, Meguro S, Tsunakawa A, Masamune S. Catalytic antibodies generated via homologous and heterologous immunization Journal of the American Chemical Society. 117: 11390-11396. DOI: 10.1021/ja00151a002  0.96
1990 Suga H, Schlosser M. α-Fluoro- and α,α-difluoroalkanals by substitution of vicinal bromofluoroalkanes and subsequent pummerer rearrangement Tetrahedron. 46: 4261-4264. DOI: 10.1016/S0040-4020(01)86763-6  0.96
1983 Suga H, Goto Y. Hemodynamic property of the ischemic myocardium Nippon Rinsho. Japanese Journal of Clinical Medicine. 41: 258-264. PMID 6345842  0.36
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