Nicholas E. Geacintov - Publications

Affiliations: 
New York University, New York, NY, United States 
Area:
Biochemistry

295 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Cai Y, Geacintov NE, Broyde S. Variable impact of conformationally distinct DNA lesions on nucleosome structure and dynamics: Implications for nucleotide excision repair. Dna Repair. 87: 102768. PMID 32018112 DOI: 10.1016/j.dnarep.2019.102768  1
2019 Ji S, Park D, Kropachev K, Kolbanovskiy M, Fu I, Broyde S, Essawy M, Geacintov NE, Tretyakova NY. 5-Formylcytosine-induced DNA-peptide cross-links reduce transcription efficiency, but do not do cause transcription errors in human cells. The Journal of Biological Chemistry. PMID 31597704 DOI: 10.1074/jbc.RA119.009834  1
2019 Chatgilialoglu C, Ferreri C, Geacintov NE, Krokidis MG, Liu Y, Masi A, Shafirovich V, Terzidis MA, Tsegay PS. 5',8-Cyclopurine Lesions in DNA Damage: Chemical, Analytical, Biological, and Diagnostic Significance. Cells. 8. PMID 31141888 DOI: 10.3390/cells8060513  0.68
2019 Shafirovich V, Kropachev K, Kolbanovskiy M, Geacintov NE. Excision of Oxidatively Generated Guanine Lesions by Competing Base and Nucleotide Excision Repair Mechanisms in Human Cells. Chemical Research in Toxicology. PMID 30688445 DOI: 10.1021/acs.chemrestox.8b00411  0.68
2018 Shafirovich V, Kolbanovskiy M, Kropachev K, Liu Z, Cai Y, Terzidis MA, Masi A, Chatgilialoglu C, Amin S, Dadali A, Broyde S, Geacintov NE. Nucleotide Excision Repair and Impact of Site-Specific 5',8-Cyclopurine and Bulky DNA Lesions on the Physical Properties of Nucleosomes. Biochemistry. PMID 30570250 DOI: 10.1021/acs.biochem.8b01066  1
2018 Mu H, Zhang Y, Geacintov NE, Broyde S. Lesion sensing during initial binding by yeast XPC/Rad4: toward predicting resistance to nucleotide excision repair. Chemical Research in Toxicology. PMID 30284444 DOI: 10.1021/acs.chemrestox.8b00231  1
2018 Mu H, Geacintov NE, Broyde S, Yeo JE, Schärer OD. Molecular basis for damage recognition and verification by XPC-RAD23B and TFIIH in nucleotide excision repair. Dna Repair. PMID 30174301 DOI: 10.1016/j.dnarep.2018.08.005  1
2018 Merta TJ, Geacintov NE, Shafirovich V. Generation of 8-oxo-7,8-dihydroguanine in G-Quadruplexes Models of Human Telomer Sequences by One-Electron Oxidation. Photochemistry and Photobiology. PMID 29679477 DOI: 10.1111/php.12926  0.68
2018 Cai Y, Fu I, Geacintov NE, Zhang Y, Broyde S. Synergistic effects of H3 and H4 nucleosome tails on structure and dynamics of a lesion-containing DNA: Binding of a displaced lesion partner base to the H3 tail for GG-NER recognition. Dna Repair. 65: 73-78. PMID 29631253 DOI: 10.1016/j.dnarep.2018.02.009  1
2017 Rechkoblit O, Kolbanovskiy A, Landes H, Geacintov NE, Aggarwal AK. Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase. Nature Communications. 8: 965. PMID 29042535 DOI: 10.1038/s41467-017-01013-5  0.44
2017 Geacintov NE, Broyde S. Repair-Resistant DNA Lesions. Chemical Research in Toxicology. PMID 28750166 DOI: 10.1021/acs.chemrestox.7b00128  1
2017 Kolbanovskiy M, Chowdhury MA, Nadkarni A, Broyde S, Geacintov NE, Scicchitano DA, Shafirovich V. The Non-Bulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RNA Polymerase II Elongation in vitro. Biochemistry. PMID 28514164 DOI: 10.1021/acs.biochem.7b00295  1
2017 Mu H, Geacintov NE, Min JH, Zhang Y, Broyde S. The nucleotide excision repair lesion-recognition protein Rad4 captures a pre-flipped partner base in a benzo[a]pyrene-derived DNA lesion: how structure impacts the binding pathway. Chemical Research in Toxicology. PMID 28460163 DOI: 10.1021/acs.chemrestox.7b00074  1
2017 Fu I, Cai Y, Geacintov NE, Zhang Y, Broyde S. Nucleosome histone tail conformation and dynamics: impacts of lysine acetylation and a nearby minor groove benzo[a]pyrene-derived lesion. Biochemistry. PMID 28304160 DOI: 10.1021/acs.biochem.6b01208  1
2016 Shafirovich V, Geacintov NE. Removal of oxidatively generated DNA damage by overlapping repair pathways. Free Radical Biology & Medicine. PMID 27818219 DOI: 10.1016/j.freeradbiomed.2016.10.507  0.68
2016 Lee YA, Lee YC, Geacintov NE, Shafirovich V. Translesion synthesis past guanine(C8)-thymine(N3) intrastrand cross-links catalyzed by selected A- and Y-family polymerases. Molecular Biosystems. PMID 27102383 DOI: 10.1039/c6mb00160b  1
2016 Purohit NK, Robu M, Shah RG, Geacintov NE, Shah GM. Characterization of the interactions of PARP-1 with UV-damaged DNA in vivo and in vitro. Scientific Reports. 6: 19020. PMID 26753915 DOI: 10.1038/srep19020  1
2016 Shafirovich V, Kropachev K, Anderson T, Liu Z, Kolbanovskiy M, Martin BD, Sugden K, Shim Y, Chen X, Min JH, Geacintov NE. Base and Nucleotide Excision Repair of Oxidatively Generated Guanine Lesions in DNA. The Journal of Biological Chemistry. PMID 26733197 DOI: 10.1074/jbc.M115.693218  1
2015 Fu I, Cai Y, Zhang Y, Geacintov NE, Broyde S. Entrapment of a Histone Tail by a DNA Lesion in a Nucleosome Suggests the Lesion Impacts Epigenetic Marking: A Molecular Dynamics Study. Biochemistry. PMID 26709619 DOI: 10.1021/acs.biochem.5b01166  1
2015 Nadkarni A, Burns JA, Gandolfi A, Chowdhury MA, Cartularo L, Berens C, Geacintov NE, Scicchitano DA. Nucleotide Excision Repair and Transcription-coupled DNA Repair Abrogate the Impact of DNA Damage on Transcription. The Journal of Biological Chemistry. PMID 26559971 DOI: 10.1074/jbc.M115.685271  1
2015 Liu Z, Ding S, Kropachev K, Jia L, Amin S, Broyde S, Geacintov NE. Correction: Resistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and Function. Plos One. 10: e0142068. PMID 26512721 DOI: 10.1371/journal.pone.0142068  1
2015 Liu Z, Ding S, Kropachev K, Lei J, Amin S, Broyde S, Geacintov NE. Resistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and Function. Plos One. 10: e0137124. PMID 26340000 DOI: 10.1371/journal.pone.0137124  1
2015 Mu H, Geacintov NE, Zhang Y, Broyde S. Recognition of Damaged DNA for Nucleotide Excision Repair: A Correlated Motion Mechanism with a Mismatched cis-syn Thymine Dimer Lesion. Biochemistry. 54: 5263-7. PMID 26270861 DOI: 10.1021/acs.biochem.5b00840  1
2015 Cai Y, Kropachev K, Terzidis MA, Masi A, Chatgilialoglu C, Geacintov NE, Broyde S. Differences in the access of lesions to the nucleotide excision repair machinery in nucleosomes. Biochemistry. PMID 26091016 DOI: 10.1021/acs.biochem.5b00564  1
2015 Talhaoui I, Shafirovich V, Liu Z, Saint-Pierre C, Akishev Z, Matkarimov BT, Gasparutto D, Geacintov NE, Saparbaev M. Oxidatively Generated Guanine(C8)-Thymine(N3) Intrastrand Cross-links in Double-stranded DNA Are Repaired by Base Excision Repair Pathways. The Journal of Biological Chemistry. 290: 14610-7. PMID 25903131 DOI: 10.1074/jbc.M115.647487  1
2014 Starostenko LV, Rechkunova NI, Lebedeva NA, Kolbanovskiy A, Geacintov NE, Lavrik OI. Human DNA polymerases catalyze lesion bypass across benzo[a]pyrene-derived DNA adduct clustered with an abasic site. Dna Repair. 24: 1-9. PMID 25460917 DOI: 10.1016/j.dnarep.2014.10.005  0.4
2014 Ziv O, Zeisel A, Mirlas-Neisberg N, Swain U, Nevo R, Ben-Chetrit N, Martelli MP, Rossi R, Schiesser S, Canman CE, Carell T, Geacintov NE, Falini B, Domany E, Livneh Z. Identification of novel DNA-damage tolerance genes reveals regulation of translesion DNA synthesis by nucleophosmin. Nature Communications. 5: 5437. PMID 25421715 DOI: 10.1038/ncomms6437  1
2014 Lior-Hoffmann L, Ding S, Geacintov NE, Zhang Y, Broyde S. Structural and dynamic characterization of polymerase κ's minor groove lesion processing reveals how adduct topology impacts fidelity. Biochemistry. 53: 5683-91. PMID 25148552 DOI: 10.1021/bi5007964  1
2014 Uvaydov Y, Geacintov NE, Shafirovich V. Generation of guanine-amino acid cross-links by a free radical combination mechanism. Physical Chemistry Chemical Physics : Pccp. 16: 11729-36. PMID 24810398 DOI: 10.1039/c4cp00675e  1
2014 Lee YC, Cai Y, Mu H, Broyde S, Amin S, Chen X, Min JH, Geacintov NE. The relationships between XPC binding to conformationally diverse DNA adducts and their excision by the human NER system: is there a correlation? Dna Repair. 19: 55-63. PMID 24784728 DOI: 10.1016/j.dnarep.2014.03.026  1
2014 Rokhlenko Y, Cadet J, Geacintov NE, Shafirovich V. Mechanistic aspects of hydration of guanine radical cations in DNA. Journal of the American Chemical Society. 136: 5956-62. PMID 24689701 DOI: 10.1021/ja412471u  1
2014 Rodríguez FA, Liu Z, Lin CH, Ding S, Cai Y, Kolbanovskiy A, Kolbanovskiy M, Amin S, Broyde S, Geacintov NE. Nuclear magnetic resonance studies of an N2-guanine adduct derived from the tumorigen dibenzo[a,l]pyrene in DNA: impact of adduct stereochemistry, size, and local DNA sequence on solution conformations. Biochemistry. 53: 1827-41. PMID 24617538 DOI: 10.1021/bi4017044  1
2014 Kropachev K, Ding S, Terzidis MA, Masi A, Liu Z, Cai Y, Kolbanovskiy M, Chatgilialoglu C, Broyde S, Geacintov NE, Shafirovich V. Structural basis for the recognition of diastereomeric 5',8-cyclo-2'-deoxypurine lesions by the human nucleotide excision repair system. Nucleic Acids Research. 42: 5020-32. PMID 24615810 DOI: 10.1093/nar/gku162  1
2014 Cadet J, Wagner JR, Shafirovich V, Geacintov NE. One-electron oxidation reactions of purine and pyrimidine bases in cellular DNA. International Journal of Radiation Biology. 90: 423-32. PMID 24369822 DOI: 10.3109/09553002.2013.877176  1
2014 Cai Y, Geacintov NE, Broyde S. Ribonucleotides as nucleotide excision repair substrates. Dna Repair. 13: 55-60. PMID 24290807 DOI: 10.1016/j.dnarep.2013.10.010  1
2014 Lukashevich OV, Cherepanova NA, Kolbanovsky A, Geacintov NE, Gromova ES. Benzo[a]pyrene-derived DNA lesions decrease DNA methylation by murine methyltransferase DNMT3A2 Moscow University Chemistry Bulletin. 69: 92-96. DOI: 10.3103/S0027131414020059  1
2013 Mu H, Kropachev K, Chen Y, Zhang H, Cai Y, Geacintov NE, Broyde S. Role of structural and energetic factors in regulating repair of a bulky DNA lesion with different opposite partner bases. Biochemistry. 52: 5517-21. PMID 23902560 DOI: 10.1021/bi4009177  1
2013 Cai Y, Zheng H, Ding S, Kropachev K, Schwaid AG, Tang Y, Mu H, Wang S, Geacintov NE, Zhang Y, Broyde S. Free energy profiles of base flipping in intercalative polycyclic aromatic hydrocarbon-damaged DNA duplexes: energetic and structural relationships to nucleotide excision repair susceptibility. Chemical Research in Toxicology. 26: 1115-25. PMID 23758590 DOI: 10.1021/tx400156a  1
2013 Madugundu GS, Wagner JR, Cadet J, Kropachev K, Yun BH, Geacintov NE, Shafirovich V. Generation of guanine-thymine cross-links in human cells by one-electron oxidation mechanisms. Chemical Research in Toxicology. 26: 1031-3. PMID 23734842 DOI: 10.1021/tx400158g  1
2013 Kropachev K, Kolbanovskiy M, Liu Z, Cai Y, Zhang L, Schwaid AG, Kolbanovskiy A, Ding S, Amin S, Broyde S, Geacintov NE. Adenine-DNA adducts derived from the highly tumorigenic Dibenzo[a,l]pyrene are resistant to nucleotide excision repair while guanine adducts are not. Chemical Research in Toxicology. 26: 783-93. PMID 23570232 DOI: 10.1021/tx400080k  1
2013 Izhar L, Ziv O, Cohen IS, Geacintov NE, Livneh Z. Genomic assay reveals tolerance of DNA damage by both translesion DNA synthesis and homology-dependent repair in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 110: E1462-9. PMID 23530190 DOI: 10.1073/pnas.1216894110  1
2013 Khutsishvili I, Zhang N, Marky LA, Crean C, Patel DJ, Geacintov NE, Shafirovich V. Thermodynamic profiles and nuclear magnetic resonance studies of oligonucleotide duplexes containing single diastereomeric spiroiminodihydantoin lesions. Biochemistry. 52: 1354-63. PMID 23360616 DOI: 10.1021/bi301566v  1
2012 Tang Y, Liu Z, Ding S, Lin CH, Cai Y, Rodriguez FA, Sayer JM, Jerina DM, Amin S, Broyde S, Geacintov NE. Nuclear magnetic resonance solution structure of an N(2)-guanine DNA adduct derived from the potent tumorigen dibenzo[a,l]pyrene: intercalation from the minor groove with ruptured Watson-Crick base pairing. Biochemistry. 51: 9751-62. PMID 23121427 DOI: 10.1021/bi3013577  1
2012 Minero AS, Lukashevich OV, Cherepanova NA, Kolbanovskiy A, Geacintov NE, Gromova ES. Probing murine methyltransfease Dnmt3a interactions with benzo[a]pyrene-modified DNA by fluorescence methods. The Febs Journal. 279: 3965-80. PMID 22913541 DOI: 10.1111/j.1742-4658.2012.08756.x  0.4
2012 Mu H, Kropachev K, Wang L, Zhang L, Kolbanovskiy A, Kolbanovskiy M, Geacintov NE, Broyde S. Nucleotide excision repair of 2-acetylaminofluorene- and 2-aminofluorene-(C8)-guanine adducts: molecular dynamics simulations elucidate how lesion structure and base sequence context impact repair efficiencies. Nucleic Acids Research. 40: 9675-90. PMID 22904073 DOI: 10.1093/nar/gks788  1
2012 Lior-Hoffmann L, Wang L, Wang S, Geacintov NE, Broyde S, Zhang Y. Preferred WMSA catalytic mechanism of the nucleotidyl transfer reaction in human DNA polymerase κ elucidates error-free bypass of a bulky DNA lesion. Nucleic Acids Research. 40: 9193-205. PMID 22772988 DOI: 10.1093/nar/gks653  1
2012 Liu Y, Liu Z, Geacintov NE, Shafirovich V. Proton-coupled hole hopping in nucleosomal and free DNA initiated by site-specific hole injection. Physical Chemistry Chemical Physics : Pccp. 14: 7400-10. PMID 22526555 DOI: 10.1039/c2cp40759k  1
2012 Rokhlenko Y, Geacintov NE, Shafirovich V. Lifetimes and reaction pathways of guanine radical cations and neutral guanine radicals in an oligonucleotide in aqueous solutions. Journal of the American Chemical Society. 134: 4955-62. PMID 22329445 DOI: 10.1021/ja212186w  1
2012 Skosareva LV, Lebedeva NA, Rechkunova NI, Kolbanovskiy A, Geacintov NE, Lavrik OI. Human DNA polymerase λ catalyzes lesion bypass across benzo[a]pyrene-derived DNA adduct during base excision repair. Dna Repair. 11: 367-73. PMID 22317757 DOI: 10.1016/j.dnarep.2012.01.002  0.4
2012 Cai Y, Geacintov NE, Broyde S. Nucleotide excision repair efficiencies of bulky carcinogen-DNA adducts are governed by a balance between stabilizing and destabilizing interactions. Biochemistry. 51: 1486-99. PMID 22242833 DOI: 10.1021/bi201794x  1
2012 Ding S, Kropachev K, Cai Y, Kolbanovskiy M, Durandina SA, Liu Z, Shafirovich V, Broyde S, Geacintov NE. Structural, energetic and dynamic properties of guanine(C8)-thymine(N3) cross-links in DNA provide insights on susceptibility to nucleotide excision repair. Nucleic Acids Research. 40: 2506-17. PMID 22135299 DOI: 10.1093/nar/gkr1087  1
2012 Lim KS, Taghizadeh K, Wishnok JS, Babu IR, Shafirovich V, Geacintov NE, Dedon PC. Sequence-dependent variation in the reactivity of 8-Oxo-7,8-dihydro-2'-deoxyguanosine toward oxidation. Chemical Research in Toxicology. 25: 366-73. PMID 22103813 DOI: 10.1021/tx200422g  1
2011 Hendel A, Krijger PH, Diamant N, Goren Z, Langerak P, Kim J, Reissner T, Lee KY, Geacintov NE, Carell T, Myung K, Tateishi S, D'Andrea A, Jacobs H, Livneh Z. PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells. Plos Genetics. 7: e1002262. PMID 21931560 DOI: 10.1371/journal.pgen.1002262  1
2011 Reeves DA, Mu H, Kropachev K, Cai Y, Ding S, Kolbanovskiy A, Kolbanovskiy M, Chen Y, Krzeminski J, Amin S, Patel DJ, Broyde S, Geacintov NE. Resistance of bulky DNA lesions to nucleotide excision repair can result from extensive aromatic lesion-base stacking interactions. Nucleic Acids Research. 39: 8752-64. PMID 21764772 DOI: 10.1093/nar/gkr537  1
2011 Liu Y, Reeves D, Kropachev K, Cai Y, Ding S, Kolbanovskiy M, Kolbanovskiy A, Bolton JL, Broyde S, Van Houten B, Geacintov NE. Probing for DNA damage with β-hairpins: similarities in incision efficiencies of bulky DNA adducts by prokaryotic and human nucleotide excision repair systems in vitro. Dna Repair. 10: 684-96. PMID 21741328 DOI: 10.1016/j.dnarep.2011.04.020  1
2011 Lee YA, Liu Z, Dedon PC, Geacintov NE, Shafirovich V. Solvent exposure associated with single abasic sites alters the base sequence dependence of oxidation of guanine in DNA in GG sequence contexts. Chembiochem : a European Journal of Chemical Biology. 12: 1731-9. PMID 21656632 DOI: 10.1002/cbic.201100140  1
2011 Yun BH, Geacintov NE, Shafirovich V. Generation of guanine-thymidine cross-links in DNA by peroxynitrite/carbon dioxide. Chemical Research in Toxicology. 24: 1144-52. PMID 21513308 DOI: 10.1021/tx200139c  1
2011 Cai Y, Ding S, Geacintov NE, Broyde S. Intercalative conformations of the 14R (+)- and 14S (-)-trans-anti-DB[a,l]P-N⁶-dA adducts: molecular modeling and MD simulations. Chemical Research in Toxicology. 24: 522-31. PMID 21361377 DOI: 10.1021/tx1004002  1
2011 Krzeminski J, Kropachev K, Kolbanovskiy M, Reeves D, Kolbanovskiy A, Yun BH, Geacintov NE, Amin S, El-Bayoumy K. Inefficient nucleotide excision repair in human cell extracts of the N-(deoxyguanosin-8-yl)-6-aminochrysene and 5-(deoxyguanosin-N(2)-yl)-6-aminochrysene adducts derived from 6-nitrochrysene. Chemical Research in Toxicology. 24: 65-72. PMID 21114286 DOI: 10.1021/tx100284h  1
2010 Zheng H, Cai Y, Ding S, Tang Y, Kropachev K, Zhou Y, Wang L, Wang S, Geacintov NE, Zhang Y, Broyde S. Base flipping free energy profiles for damaged and undamaged DNA. Chemical Research in Toxicology. 23: 1868-70. PMID 21090780 DOI: 10.1021/tx1003613  1
2010 Cai Y, Wang L, Ding S, Schwaid A, Geacintov NE, Broyde S. A bulky DNA lesion derived from a highly potent polycyclic aromatic tumorigen stabilizes nucleosome core particle structure. Biochemistry. 49: 9943-5. PMID 20964331 DOI: 10.1021/bi101560y  1
2010 Cai Y, Patel DJ, Broyde S, Geacintov NE. Base sequence context effects on nucleotide excision repair. Journal of Nucleic Acids. 2010. PMID 20871811 DOI: 10.4061/2010/174252  1
2010 Shao J, Geacintov NE, Shafirovich V. Oxidative modification of guanine bases initiated by oxyl radicals derived from photolysis of azo compounds. The Journal of Physical Chemistry. B. 114: 6685-92. PMID 20415485 DOI: 10.1021/jp100686j  1
2010 Yun BH, Dedon PC, Geacintov NE, Shafirovich V. One-electron oxidation of a pyrenyl photosensitizer covalently attached to DNA and competition between its further oxidation and DNA hole injection. Photochemistry and Photobiology. 86: 563-70. PMID 20408978 DOI: 10.1111/j.1751-1097.2010.00719.x  1
2010 Shao J, Geacintov NE, Shafirovich V. Oxidation of 8-oxo-7,8-dihydro-2'-deoxyguanosine by oxyl radicals produced by photolysis of azo compounds. Chemical Research in Toxicology. 23: 933-8. PMID 20408566 DOI: 10.1021/tx100022x  1
2010 Cai Y, Kropachev K, Xu R, Tang Y, Kolbanovskii M, Kolbanovskii A, Amin S, Patel DJ, Broyde S, Geacintov NE. Distant neighbor base sequence context effects in human nucleotide excision repair of a benzo[a]pyrene-derived DNA lesion. Journal of Molecular Biology. 399: 397-409. PMID 20399214 DOI: 10.1016/j.jmb.2010.04.004  1
2010 Dreij K, Rhrissorrakrai K, Gunsalus KC, Geacintov NE, Scicchitano DA. Benzo[a]pyrene diol epoxide stimulates an inflammatory response in normal human lung fibroblasts through a p53 and JNK mediated pathway. Carcinogenesis. 31: 1149-57. PMID 20382639 DOI: 10.1093/carcin/bgq073  1
2010 Rechkoblit O, Kolbanovskiy A, Malinina L, Geacintov NE, Broyde S, Patel DJ. Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4. Nature Structural & Molecular Biology. 17: 379-88. PMID 20154704 DOI: 10.1038/nsmb.1771  1
2010 Gromova ES, Subach OM, Baskunov VB, Geacintov NE. Impact of carcinogen-DNA adducts on DNA methylation Acs Symposium Series. 1041: 103-116. DOI: 10.1021/bk-2010-1041.ch007  1
2010 Shafirovich V, Geacintov NE. Role of Free Radical Reactions in the Formation of DNA Damage The Chemical Biology of Dna Damage. 81-104. DOI: 10.1002/9783527630110.ch4  1
2010 Broyde S, Wang L, Patel DJ, Geacintov NE. Elucidating Structure-Function Relationships in Bulky DNA Lesions: From Solution Structures to Polymerases The Chemical Biology of Dna Damage. 331-352. DOI: 10.1002/9783527630110.ch14  1
2010 Geacintov NE, Broyde S. Introduction and Perspectives on the Chemistry and Biology of DNA Damage The Chemical Biology of Dna Damage. 1-20. DOI: 10.1002/9783527630110.ch1  1
2010 Geacintov NE, Broyde S. The Chemical Biology of DNA Damage The Chemical Biology of Dna Damage. 1-449. DOI: 10.1002/9783527630110  1
2009 Ding S, Kolbanovskiy A, Durandin A, Crean C, Shafirovich V, Broyde S, Geacintov NE. Absolute configurations of DNA lesions determined by comparisons of experimental ECD and ORD spectra with DFT calculations. Chirality. 21: E231-41. PMID 19937959 DOI: 10.1002/chir.20804  1
2009 Crean C, Shao J, Yun BH, Geacintov NE, Shafirovich V. The role of one-electron reduction of lipid hydroperoxides in causing DNA damage. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 10634-40. PMID 19746460 DOI: 10.1002/chem.200900500  1
2009 Crean C, Geacintov NE, Shafirovich V. Methylation of 2'-deoxyguanosine by a free radical mechanism. The Journal of Physical Chemistry. B. 113: 12773-81. PMID 19719172 DOI: 10.1021/jp903554n  1
2009 Jia L, Kropachev K, Ding S, Van Houten B, Geacintov NE, Broyde S. Exploring damage recognition models in prokaryotic nucleotide excision repair with a benzo[a]pyrene-derived lesion in UvrB. Biochemistry. 48: 8948-57. PMID 19681599 DOI: 10.1021/bi9010072  1
2009 Zhang N, Ding S, Kolbanovskiy A, Shastry A, Kuzmin VA, Bolton JL, Patel DJ, Broyde S, Geacintov NE. NMR and computational studies of stereoisomeric equine estrogen-derived DNA cytidine adducts in oligonucleotide duplexes: opposite orientations of diastereomeric forms. Biochemistry. 48: 7098-109. PMID 19527068 DOI: 10.1021/bi9006429  1
2009 Ding S, Jia L, Durandin A, Crean C, Kolbanovskiy A, Shafirovich V, Broyde S, Geacintov NE. Absolute configurations of spiroiminodihydantoin and allantoin stereoisomers: comparison of computed and measured electronic circular dichroism spectra. Chemical Research in Toxicology. 22: 1189-93. PMID 19485408 DOI: 10.1021/tx900107q  1
2009 Rechkoblit O, Malinina L, Cheng Y, Geacintov NE, Broyde S, Patel DJ. Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases. Structure (London, England : 1993). 17: 725-36. PMID 19446528 DOI: 10.1016/j.str.2009.03.011  1
2009 Wang Z, Edirisinghe P, Sohn J, Qin Z, Geacintov NE, Thatcher GR, Bolton JL. Development of a liquid chromatography electrospray ionization tandem mass spectrometry method for analysis of stable 4-hydroxyequilenin-DNA adducts in human breast cancer cells. Chemical Research in Toxicology. 22: 1129-36. PMID 19368368 DOI: 10.1021/tx900063g  1
2009 Xu P, Oum L, Lee YC, Geacintov NE, Broyde S. Visualizing sequence-governed nucleotide selectivities and mutagenic consequences through a replicative cycle: processing of a bulky carcinogen N2-dG lesion in a Y-family DNA polymerase. Biochemistry. 48: 4677-90. PMID 19364137 DOI: 10.1021/bi802363f  1
2009 Kropachev K, Kolbanovskii M, Cai Y, Rodríguez F, Kolbanovskii A, Liu Y, Zhang L, Amin S, Patel D, Broyde S, Geacintov NE. The sequence dependence of human nucleotide excision repair efficiencies of benzo[a]pyrene-derived DNA lesions: insights into the structural factors that favor dual incisions. Journal of Molecular Biology. 386: 1193-203. PMID 19162041 DOI: 10.1016/j.jmb.2008.12.082  1
2009 Cai Y, Patel DJ, Geacintov NE, Broyde S. Differential nucleotide excision repair susceptibility of bulky DNA adducts in different sequence contexts: hierarchies of recognition signals. Journal of Molecular Biology. 385: 30-44. PMID 18948114 DOI: 10.1016/j.jmb.2008.09.087  1
2009 Shafirovich V, Crean C, Geacintov NE. Reactions of Reactive Nitrogen Species and Carbonate Radical Anions with DNA Radical and Radical Ion Reactivity in Nucleic Acid Chemistry. 325-355. DOI: 10.1002/9780470526279.ch11  1
2008 Margolin Y, Shafirovich V, Geacintov NE, DeMott MS, Dedon PC. DNA sequence context as a determinant of the quantity and chemistry of guanine oxidation produced by hydroxyl radicals and one-electron oxidants. The Journal of Biological Chemistry. 283: 35569-78. PMID 18948263 DOI: 10.1074/jbc.M806809200  1
2008 Jia L, Geacintov NE, Broyde S. The N-clasp of human DNA polymerase kappa promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesions. Nucleic Acids Research. 36: 6571-84. PMID 18931375 DOI: 10.1093/nar/gkn719  1
2008 Crean C, Geacintov NE, Shafirovich V. Intrastrand G-U cross-links generated by the oxidation of guanine in 5'-d(GCU) and 5'-r(GCU). Free Radical Biology & Medicine. 45: 1125-34. PMID 18692567 DOI: 10.1016/j.freeradbiomed.2008.07.008  1
2008 Ding S, Wang Y, Kolbanovskiy A, Durandin A, Bolton JL, van Breemen RB, Broyde S, Geacintov NE. Determination of absolute configurations of 4-hydroxyequilenin-cytosine and -adenine adducts by optical rotatory dispersion, electronic circular dichroism, density functional theory calculations, and mass spectrometry. Chemical Research in Toxicology. 21: 1739-48. PMID 18680315 DOI: 10.1021/tx800095f  1
2008 Crean C, Lee YA, Yun BH, Geacintov NE, Shafirovich V. Oxidation of guanine by carbonate radicals derived from photolysis of carbonatotetramminecobalt(III) complexes and the pH dependence of intrastrand DNA cross-links mediated by guanine radical reactions. Chembiochem : a European Journal of Chemical Biology. 9: 1985-91. PMID 18655084 DOI: 10.1002/cbic.200800105  1
2008 Dimitri A, Jia L, Shafirovich V, Geacintov NE, Broyde S, Scicchitano DA. Transcription of DNA containing the 5-guanidino-4-nitroimidazole lesion by human RNA polymerase II and bacteriophage T7 RNA polymerase. Dna Repair. 7: 1276-88. PMID 18555749 DOI: 10.1016/j.dnarep.2008.04.007  1
2008 Ding S, Shapiro R, Cai Y, Geacintov NE, Broyde S. Conformational properties of equilenin-DNA adducts: stereoisomer and base effects. Chemical Research in Toxicology. 21: 1064-73. PMID 18416538 DOI: 10.1021/tx800010u  1
2008 Broyde S, Wang L, Rechkoblit O, Geacintov NE, Patel DJ. Lesion processing: high-fidelity versus lesion-bypass DNA polymerases. Trends in Biochemical Sciences. 33: 209-19. PMID 18407502 DOI: 10.1016/j.tibs.2008.02.004  1
2008 Xu P, Oum L, Geacintov NE, Broyde S. Nucleotide selectivity opposite a benzo[a]pyrene-derived N2-dG adduct in a Y-family DNA polymerase: a 5'-slippage mechanism. Biochemistry. 47: 2701-9. PMID 18260644 DOI: 10.1021/bi701839q  1
2008 Lee YA, Durandin A, Dedon PC, Geacintov NE, Shafirovich V. Oxidation of guanine in G, GG, and GGG sequence contexts by aromatic pyrenyl radical cations and carbonate radical anions: relationship between kinetics and distribution of alkali-labile lesions. The Journal of Physical Chemistry. B. 112: 1834-44. PMID 18211057 DOI: 10.1021/jp076777x  1
2008 Crean C, Geacintov NE, Shafirovich V. Pathways of arachidonic acid peroxyl radical reactions and product formation with guanine radicals. Chemical Research in Toxicology. 21: 358-73. PMID 18159932 DOI: 10.1021/tx700281e  1
2008 Crean C, Uvaydov Y, Geacintov NE, Shafirovich V. Oxidation of single-stranded oligonucleotides by carbonate radical anions: generating intrastrand cross-links between guanine and thymine bases separated by cytosines. Nucleic Acids Research. 36: 742-55. PMID 18084033 DOI: 10.1093/nar/gkm1092  1
2008 Broyde S, Wang L, Zhang L, Rechkoblit O, Geacintov NE, Patel DJ. DNA adduct structure-function relationships: comparing solution with polymerase structures. Chemical Research in Toxicology. 21: 45-52. PMID 18052109 DOI: 10.1021/tx700193x  1
2008 Breton J, Geacintov NE. Chlorophyll Orientation and Exciton Migration in the Photosynthetic Membrane Chlorophyll Organization and Energy Transfer in Photosynthesis. 217-236. DOI: 10.1002/9780470720431.ch12  1
2007 Cai Y, Patel DJ, Geacintov NE, Broyde S. Dynamics of a benzo[a]pyrene-derived guanine DNA lesion in TGT and CGC sequence contexts: enhanced mobility in TGT explains conformational heterogeneity, flexible bending, and greater susceptibility to nucleotide excision repair. Journal of Molecular Biology. 374: 292-305. PMID 17942115 DOI: 10.1016/j.jmb.2007.09.034  1
2007 Yun BH, Lee YA, Kim SK, Kuzmin V, Kolbanovskiy A, Dedon PC, Geacintov NE, Shafirovich V. Photosensitized oxidative DNA damage: from hole injection to chemical product formation and strand cleavage. Journal of the American Chemical Society. 129: 9321-32. PMID 17616188 DOI: 10.1021/ja066954s  1
2007 Xu P, Oum L, Beese LS, Geacintov NE, Broyde S. Following an environmental carcinogen N2-dG adduct through replication: elucidating blockage and bypass in a high-fidelity DNA polymerase. Nucleic Acids Research. 35: 4275-88. PMID 17576677 DOI: 10.1093/nar/gkm416  1
2007 Mocquet V, Kropachev K, Kolbanovskiy M, Kolbanovskiy A, Tapias A, Cai Y, Broyde S, Geacintov NE, Egly JM. The human DNA repair factor XPC-HR23B distinguishes stereoisomeric benzo[a]pyrenyl-DNA lesions. The Embo Journal. 26: 2923-32. PMID 17525733 DOI: 10.1038/sj.emboj.7601730  1
2007 Ruan Q, Liu T, Kolbanovskiy A, Liu Y, Ren J, Skorvaga M, Zou Y, Lader J, Malkani B, Amin S, Van Houten B, Geacintov NE. Sequence context- and temperature-dependent nucleotide excision repair of a benzo[a]pyrene diol epoxide-guanine DNA adduct catalyzed by thermophilic UvrABC proteins. Biochemistry. 46: 7006-15. PMID 17506530 DOI: 10.1021/bi700294k  0.64
2007 Jia L, Shafirovich V, Geacintov NE, Broyde S. Lesion specificity in the base excision repair enzyme hNeil1: modeling and dynamics studies. Biochemistry. 46: 5305-14. PMID 17432829 DOI: 10.1021/bi062269m  1
2007 Subach OM, Maltseva DV, Shastry A, Kolbanovskiy A, Klimasauskas S, Geacintov NE, Gromova ES. The stereochemistry of benzo[a]pyrene-2'-deoxyguanosine adducts affects DNA methylation by SssI and HhaI DNA methyltransferases. The Febs Journal. 274: 2121-34. PMID 17388812 DOI: 10.1111/j.1742-4658.2007.05754.x  0.4
2007 Lee YA, Yun BH, Kim SK, Margolin Y, Dedon PC, Geacintov NE, Shafirovich V. Mechanisms of oxidation of guanine in DNA by carbonate radical anion, a decomposition product of nitrosoperoxycarbonate. Chemistry (Weinheim An Der Bergstrasse, Germany). 13: 4571-81. PMID 17335089 DOI: 10.1002/chem.200601434  1
2007 Rodríguez FA, Cai Y, Lin C, Tang Y, Kolbanovskiy A, Amin S, Patel DJ, Broyde S, Geacintov NE. Exocyclic amino groups of flanking guanines govern sequence-dependent adduct conformations and local structural distortions for minor groove-aligned benzo[a]pyrenyl-guanine lesions in a GG mutation hotspot context. Nucleic Acids Research. 35: 1555-68. PMID 17287290 DOI: 10.1093/nar/gkm022  1
2007 Ding S, Shapiro R, Geacintov NE, Broyde S. 4-hydroxyequilenin-adenine lesions in DNA duplexes: stereochemistry, damage site, and structure. Biochemistry. 46: 182-91. PMID 17198388 DOI: 10.1021/bi061652o  1
2007 Perlow-Poehnelt RA, Likhterov I, Wang L, Scicchitano DA, Geacintov NE, Broyde S. Increased flexibility enhances misincorporation: temperature effects on nucleotide incorporation opposite a bulky carcinogen-DNA adduct by a Y-family DNA polymerase. The Journal of Biological Chemistry. 282: 1397-408. PMID 17090533 DOI: 10.1074/jbc.M606769200  1
2006 Durandin A, Jia L, Crean C, Kolbanovskiy A, Ding S, Shafirovich V, Broyde S, Geacintov NE. Assignment of absolute configurations of the enantiomeric spiroiminodihydantoin nucleobases by experimental and computational optical rotatory dispersion methods. Chemical Research in Toxicology. 19: 908-13. PMID 16841958 DOI: 10.1021/tx060078e  1
2006 Margolin Y, Cloutier JF, Shafirovich V, Geacintov NE, Dedon PC. Paradoxical hotspots for guanine oxidation by a chemical mediator of inflammation. Nature Chemical Biology. 2: 365-6. PMID 16751762 DOI: 10.1038/nchembio796  1
2006 Jia L, Shafirovich V, Shapiro R, Geacintov NE, Broyde S. Flexible 5-guanidino-4-nitroimidazole DNA lesions: structures and thermodynamics. Biochemistry. 45: 6644-55. PMID 16716075 DOI: 10.1021/bi0601757  1
2006 Subach OM, Baskunov VB, Darii MV, Maltseva DV, Alexandrov DA, Kirsanova OV, Kolbanovskiy A, Kolbanovskiy M, Johnson F, Bonala R, Geacintov NE, Gromova ES. Impact of benzo[a]pyrene-2'-deoxyguanosine lesions on methylation of DNA by SssI and HhaI DNA methyltransferases. Biochemistry. 45: 6142-59. PMID 16681387 DOI: 10.1021/bi0511639  1
2006 Royzen M, Durandin A, Young VG, Geacintov NE, Canary JW. A sensitive probe for the detection of Zn(II) by time-resolved fluorescence. Journal of the American Chemical Society. 128: 3854-5. PMID 16551061 DOI: 10.1021/ja056631g  1
2006 Zhao B, Wang J, Geacintov NE, Wang Z. Poleta, Polzeta and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cells. Nucleic Acids Research. 34: 417-25. PMID 16415180 DOI: 10.1093/nar/gkj446  1
2006 Rechkoblit O, Malinina L, Cheng Y, Kuryavyi V, Broyde S, Geacintov NE, Patel DJ. Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion. Plos Biology. 4: e11. PMID 16379496 DOI: 10.1371/journal.pbio.0040011  1
2006 Shafirovich V, Geacintov NE. Spectroscopic Investigation of Charge Transfer in DNA Charge Transfer in Dna: From Mechanism to Application. 175-196. DOI: 10.1002/3527606629.ch8  1
2005 Kolbanovskiy A, Kuzmin V, Shastry A, Kolbanovskaya M, Chen D, Chang M, Bolton JL, Geacintov NE. Base selectivity and effects of sequence and DNA secondary structure on the formation of covalent adducts derived from the equine estrogen metabolite 4-hydroxyequilenin. Chemical Research in Toxicology. 18: 1737-47. PMID 16300383 DOI: 10.1021/tx050190x  1
2005 Ding S, Shapiro R, Geacintov NE, Broyde S. Equilenin-derived DNA adducts to cytosine in DNA duplexes: structures and thermodynamics. Biochemistry. 44: 14565-76. PMID 16262256 DOI: 10.1021/bi051090t  1
2005 Jia L, Shafirovich V, Shapiro R, Geacintov NE, Broyde S. Structural and thermodynamic features of spiroiminodihydantoin damaged DNA duplexes. Biochemistry. 44: 13342-53. PMID 16201759 DOI: 10.1021/bi050790v  1
2005 Crean C, Geacintov NE, Shafirovich V. Oxidation of guanine and 8-oxo-7,8-dihydroguanine by carbonate radical anions: insight from oxygen-18 labeling experiments. Angewandte Chemie (International Ed. in English). 44: 5057-60. PMID 16013075 DOI: 10.1002/anie.200500991  1
2005 Suzuki N, Yasui M, Geacintov NE, Shafirovich V, Shibutani S. Miscoding events during DNA synthesis past the nitration-damaged base 8-nitroguanine. Biochemistry. 44: 9238-45. PMID 15966748 DOI: 10.1021/bi050276p  1
2005 Jia L, Shafirovich V, Shapiro R, Geacintov NE, Broyde S. Spiroiminodihydantoin lesions derived from guanine oxidation: structures, energetics, and functional implications. Biochemistry. 44: 6043-51. PMID 15835893 DOI: 10.1021/bi0473657  1
2005 Wang L, Wu M, Yan SF, Patel DJ, Geacintov NE, Broyde S. Accommodation of a 1S-(-)-benzo[c]phenanthrenyl-N6-dA adduct in the Y-family Dpo4 DNA polymerase active site: structural insights through molecular dynamics simulations. Chemical Research in Toxicology. 18: 441-56. PMID 15777084 DOI: 10.1021/tx049786v  1
2005 Misiaszek R, Crean C, Geacintov NE, Shafirovich V. Combination of nitrogen dioxide radicals with 8-oxo-7,8-dihydroguanine and guanine radicals in DNA: oxidation and nitration end-products. Journal of the American Chemical Society. 127: 2191-200. PMID 15713097 DOI: 10.1021/ja044390r  1
2005 Zhang N, Lin C, Huang X, Kolbanovskiy A, Hingerty BE, Amin S, Broyde S, Geacintov NE, Patel DJ. Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement. Journal of Molecular Biology. 346: 951-65. PMID 15701509 DOI: 10.1016/j.jmb.2004.12.027  1
2005 Baskunov VB, Subach FV, Kolbanovskiy A, Kolbanovskiy M, Eremin SA, Johnson F, Bonala R, Geacintov NE, Gromova ES. Effects of benzo[a]pyrene-deoxyguanosine lesions on DNA methylation catalyzed by EcoRII DNA methyltransferase and on DNA cleavage effected by EcoRII restriction endonuclease. Biochemistry. 44: 1054-66. PMID 15654762 DOI: 10.1021/bi048130y  0.68
2005 Misiaszek R, Uvaydov Y, Crean C, Geacintov NE, Shafirovich V. Combination reactions of superoxide with 8-Oxo-7,8-dihydroguanine radicals in DNA: kinetics and end products. The Journal of Biological Chemistry. 280: 6293-300. PMID 15590679 DOI: 10.1074/jbc.M412253200  1
2005 Hsu GW, Huang X, Luneva NP, Geacintov NE, Beese LS. Structure of a high fidelity DNA polymerase bound to a benzo[a]pyrene adduct that blocks replication. The Journal of Biological Chemistry. 280: 3764-70. PMID 15548515 DOI: 10.1074/jbc.M411276200  1
2005 Naegeli H, Geacintov NE. Mechanisms of repair of polycyclic aromatic hydrocarbon-induced DNA damage The Carcinogenic Effects of Polycyclic Aromatic Hydrocarbons. 211-258. DOI: 10.1142/9781860949333_0006  1
2004 Wu M, Yan SF, Tan J, Patel DJ, Geacintov NE, Broyde S. Conformational searches elucidate effects of stereochemistry on structures of deoxyadenosine covalently bound to tumorigenic metabolites of benzo[C] phenanthrene. Frontiers in Bioscience : a Journal and Virtual Library. 9: 2807-18. PMID 15353316  1
2004 Perlow-Poehnelt RA, Likhterov I, Scicchitano DA, Geacintov NE, Broyde S. The spacious active site of a Y-family DNA polymerase facilitates promiscuous nucleotide incorporation opposite a bulky carcinogen-DNA adduct: elucidating the structure-function relationship through experimental and computational approaches. The Journal of Biological Chemistry. 279: 36951-61. PMID 15210693 DOI: 10.1074/jbc.M404332200  1
2004 Yan SF, Wu M, Geacintov NE, Broyde S. Altering DNA polymerase incorporation fidelity by distorting the dNTP binding pocket with a bulky carcinogen-damaged template. Biochemistry. 43: 7750-65. PMID 15196018 DOI: 10.1021/bi0499516  1
2004 Misiaszek R, Crean C, Joffe A, Geacintov NE, Shafirovich V. Oxidative DNA damage associated with combination of guanine and superoxide radicals and repair mechanisms via radical trapping. The Journal of Biological Chemistry. 279: 32106-15. PMID 15152004 DOI: 10.1074/jbc.M313904200  1
2004 Zou Y, Ma H, Minko IG, Shell SM, Yang Z, Qu Y, Xu Y, Geacintov NE, Lloyd RS. DNA damage recognition of mutated forms of UvrB proteins in nucleotide excision repair. Biochemistry. 43: 4196-205. PMID 15065863 DOI: 10.1021/bi035992a  1
2003 Joffe A, Geacintov NE, Shafirovich V. DNA lesions derived from the site selective oxidation of Guanine by carbonate radical anions. Chemical Research in Toxicology. 16: 1528-38. PMID 14680366 DOI: 10.1021/tx034142t  1
2003 Zou Y, Shell SM, Utzat CD, Luo C, Yang Z, Geacintov NE, Basu AK. Effects of DNA adduct structure and sequence context on strand opening of repair intermediates and incision by UvrABC nuclease. Biochemistry. 42: 12654-61. PMID 14580212 DOI: 10.1021/bi034446e  1
2003 Schinecker TM, Perlow RA, Broyde S, Geacintov NE, Scicchitano DA. Human RNA polymerase II is partially blocked by DNA adducts derived from tumorigenic benzo[c]phenanthrene diol epoxides: relating biological consequences to conformational preferences. Nucleic Acids Research. 31: 6004-15. PMID 14530448 DOI: 10.1093/nar/gkg771  1
2003 Xie Z, Braithwaite E, Guo D, Zhao B, Geacintov NE, Wang Z. Mutagenesis of benzo[a]pyrene diol epoxide in yeast: requirement for DNA polymerase zeta and involvement of DNA polymerase eta. Biochemistry. 42: 11253-62. PMID 14503875 DOI: 10.1021/bi0346704  0.44
2003 Joffe A, Mock S, Yun BH, Kolbanovskiy A, Geacintov NE, Shafirovich V. Oxidative generation of guanine radicals by carbonate radicals and their reactions with nitrogen dioxide to form site specific 5-guanidino-4-nitroimidazole lesions in oligodeoxynucleotides. Chemical Research in Toxicology. 16: 966-73. PMID 12924924 DOI: 10.1021/tx025578w  1
2003 Ding S, Shapiro R, Geacintov NE, Broyde S. Conformations of stereoisomeric base adducts to 4-hydroxyequilenin. Chemical Research in Toxicology. 16: 695-707. PMID 12807352 DOI: 10.1021/tx0340246  1
2003 Yan S, Wu M, Patel DJ, Geacintov NE, Broyde S. Simulating structural and thermodynamic properties of carcinogen-damaged DNA. Biophysical Journal. 84: 2137-48. PMID 12668423 DOI: 10.1016/S0006-3495(03)75020-6  1
2003 Perlow RA, Schinecker TM, Kim SJ, Geacintov NE, Scicchitano DA. Construction and purification of site-specifically modified DNA templates for transcription assays. Nucleic Acids Research. 31: e40. PMID 12655028  1
2003 Muheim R, Buterin T, Colgate KC, Kolbanovsij A, Geacintov NE, Naegeli H. Modulation of human nucleotide excision repair by 5-methylcytosines. Biochemistry. 42: 3247-54. PMID 12641456 DOI: 10.1021/bi0268504  1
2003 Huang X, Kolbanovskiy A, Wu X, Zhang Y, Wang Z, Zhuang P, Amin S, Geacintov NE. Effects of base sequence context on translesion synthesis past a bulky (+)-trans-anti-B[a]P-N2-dG lesion catalyzed by the Y-family polymerase pol kappa. Biochemistry. 42: 2456-66. PMID 12600213 DOI: 10.1021/bi026912q  0.76
2003 Yan S, Wu M, Buterin T, Naegeli H, Geacintov NE, Broyde S. Role of base sequence context in conformational equilibria and nucleotide excision repair of benzo[a]pyrene diol epoxide-adenine adducts. Biochemistry. 42: 2339-54. PMID 12600201 DOI: 10.1021/bi0270081  1
2003 Shafirovich V, Singh C, Geacintov NE. Photoinduced Oxidative DNA Damage Revealed by an Agarose Gel Nicking Assay: A Biophysical Chemistry Laboratory Experiment Journal of Chemical Education. 80: 1297-1299.  1
2002 Zhang Y, Wu X, Guo D, Rechkoblit O, Geacintov NE, Wang Z. Two-step error-prone bypass of the (+)- and (-)-trans-anti-BPDE-N2-dG adducts by human DNA polymerases eta and kappa. Mutation Research. 510: 23-35. PMID 12459440  0.76
2002 Geacintov NE, Broyde S, Buterin T, Naegeli H, Wu M, Yan S, Patel DJ. Thermodynamic and structural factors in the removal of bulky DNA adducts by the nucleotide excision repair machinery. Biopolymers. 65: 202-10. PMID 12228925 DOI: 10.1002/bip.10239  1
2002 Zhang Y, Wu X, Guo D, Rechkoblit O, Taylor JS, Geacintov NE, Wang Z. Lesion bypass activities of human DNA polymerase mu. The Journal of Biological Chemistry. 277: 44582-7. PMID 12228225 DOI: 10.1074/jbc.M207297200  0.76
2002 Buterin T, Hess MT, Gunz D, Geacintov NE, Mullenders LH, Naegeli H. Trapping of DNA nucleotide excision repair factors by nonrepairable carcinogen adducts. Cancer Research. 62: 4229-35. PMID 12154024  1
2002 Wu M, Yan S, Patel DJ, Geacintov NE, Broyde S. Relating repair susceptibility of carcinogen-damaged DNA with structural distortion and thermodynamic stability. Nucleic Acids Research. 30: 3422-32. PMID 12140327  1
2002 Perlow RA, Kolbanovskii A, Hingerty BE, Geacintov NE, Broyde S, Scicchitano DA. DNA adducts from a tumorigenic metabolite of benzo[a]pyrene block human RNA polymerase II elongation in a sequence- and stereochemistry-dependent manner. Journal of Molecular Biology. 321: 29-47. PMID 12139931 DOI: 10.1016/S0022-2836(02)00593-4  1
2002 Rechkoblit O, Zhang Y, Guo D, Wang Z, Amin S, Krzeminsky J, Louneva N, Geacintov NE. trans-Lesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases. The Journal of Biological Chemistry. 277: 30488-94. PMID 12063247 DOI: 10.1074/jbc.M201167200  0.76
2002 Yan S, Wu M, Ding S, Geacintov NE, Broyde S. Conformational analysis of a 4-hydroxyequilenin Guanine adduct using density functional theory. Chemical Research in Toxicology. 15: 648-53. PMID 12018985 DOI: 10.1021/tx0101797  1
2002 Shafirovich V, Mock S, Kolbanovskiy A, Geacintov NE. Photochemically catalyzed generation of site-specific 8-nitroguanine adducts in DNA by the reaction of long-lived neutral guanine radicals with nitrogen dioxide Chemical Research in Toxicology. 15: 591-597. PMID 11952346 DOI: 10.1021/tx015593l  1
2002 Huang X, Colgate KC, Kolbanovskiy A, Amin S, Geacintov NE. Conformational changes of a benzo[a]pyrene diol epoxide-N(2)-dG adduct induced by a 5'-flanking 5-methyl-substituted cytosine in a (Me)CG double-stranded oligonucleotide sequence context. Chemical Research in Toxicology. 15: 438-44. PMID 11896693 DOI: 10.1021/tx015588h  1
2002 Ruan Q, Kolbanovskiy A, Zhuang P, Chen J, Krzeminski J, Amin S, Geacintov NE. Synthesis and characterization of site-specific and stereoisomeric fjord dibenzo[a,l]pyrene diol epoxide-N(6)-adenine adducts: unusual thermal stabilization of modified DNA duplexes. Chemical Research in Toxicology. 15: 249-61. PMID 11849052  0.56
2002 Huang W, Amin S, Geacintov NE. Fluorescence characteristics of site-specific and stereochemically distinct benzo[a]pyrene diol epoxide-DNA adducts as probes of adduct conformation. Chemical Research in Toxicology. 15: 118-26. PMID 11849037 DOI: 10.1021/tx010135y  1
2001 Ruan Q, Zhuang P, Li S, Perlow R, Srinivasan AR, Lu XJ, Broyde S, Olson WK, Geacintov NE. Base sequence effects in bending induced by bulky carcinogen-DNA adducts: experimental and computational analysis. Biochemistry. 40: 10458-72. PMID 11523987 DOI: 10.1021/bi002643x  1
2001 Yan S, Shapiro R, Geacintov NE, Broyde S. Stereochemical, structural, and thermodynamic origins of stability differences between stereoisomeric benzo[a]pyrene diol epoxide deoxyadenosine adducts in a DNA mutational hot spot sequence. Journal of the American Chemical Society. 123: 7054-66. PMID 11459484 DOI: 10.1021/ja0043035  1
2001 Zhuang P, Kolbanovskiy A, Amin S, Geacintov NE. Base sequence dependence of in vitro translesional DNA replication past a bulky lesion catalyzed by the exo- Klenow fragment of Pol I. Biochemistry. 40: 6660-9. PMID 11380261 DOI: 10.1021/bi010005o  1
2001 Shafirovich V, Dourandin A, Huang W, Geacintov NE. The carbonate radical is a site-selective oxidizing agent of guanine in double-stranded oligonucleotides. The Journal of Biological Chemistry. 276: 24621-6. PMID 11320091 DOI: 10.1074/jbc.M101131200  1
2001 Roth RB, Amin S, Geacintov NE, Scicchitano DA. Bacteriophage T7 RNA polymerase transcription elongation is inhibited by site-specific, stereospecific benzo[c]phenanthrene diol epoxide DNA lesions Biochemistry. 40: 5200-5207. PMID 11318642  1
2001 Shafirovich V, Cadet J, Gasparutto D, Dourandin A, Geacintov NE. Nitrogen dioxide as an oxidizing agent of 8-oxo-7,8-dihydro-2′-deoxyguanosine but not of 2′-deoxyguanosine Chemical Research in Toxicology. 14: 233-241. PMID 11258973 DOI: 10.1021/tx000204t  1
2001 Zou Y, Luo C, Geacintov NE. Hierarchy of DNA damage recognition in Escherichia coli nucleotide excision repair Biochemistry. 40: 2923-2931. PMID 11258904 DOI: 10.1021/bi001504c  1
2001 Lin CH, Huang X, Kolbanovskii A, Hingerty BE, Amin S, Broyde S, Geacintov NE, Patel DJ. Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity. Journal of Molecular Biology. 306: 1059-80. PMID 11237618 DOI: 10.1006/jmbi.2001.4425  1
2001 Shafirovich V, Dourandin A, Geacintov NE. Proton-coupled electron-transfer reactions at a distance in DNA duplexes: Kinetic deuterium isotope effect Journal of Physical Chemistry B. 105: 8431-8435. DOI: 10.1021/jp0044734  1
2000 Tan J, Geacintov NE, Broyde S. Conformational determinants of structures in stereoisomeric cis-opened anti-benzo[a]pyrene diol epoxide adducts to adenine in DNA. Chemical Research in Toxicology. 13: 811-22. PMID 10995253 DOI: 10.1021/tx000094q  1
2000 Shafirovich V, Dourandin A, Huang W, Luneva NP, Geacintov NE. Electron transfer at a distance induced by site-selective photoionization of 2-aminopurine in oligonucleotides and investigated by transient absorption techniques Physical Chemistry Chemical Physics. 2: 4399-4408. DOI: 10.1039/b004896h  1
2000 Kuzmin VA, Dourandin A, Shafirovich V, Geacintov NE. Proton-coupled electron transfer in the oxidation of guanines by an aromatic pyrenyl radical cation in aqueous solutions Physical Chemistry Chemical Physics. 2: 1531-1535. DOI: 10.1039/b000212g  1
2000 Tan J, Geacintov NE, Broyde S. Principles governing conformations in stereoisomeric adducts of Bay region benzo[a]pyrene diol epoxides to adenine in DNA: Steric and hydrophobic effects are dominant Journal of the American Chemical Society. 122: 3021-3032. DOI: 10.1021/ja993624h  1
2000 Shafirovich V, Dourandin A, Luneva NP, Geacintov NE. Acid-base equilibria in aqueous solutions of 2-aminopurine radical cations generated by two-photon photoionization Journal of the Chemical Society. Perkin Transactions 2. 271-275.  1
2000 Tsao H, Rechkoblit O, Amin S, Geacintov NE. Impact of site-specific benzo[a]pyrene diol epoxide-dg lesions at or near single/double-strand DNA junctions on DNA bending Polycyclic Aromatic Compounds. 21: 1-10.  1
2000 Shafirovich V, Dourandin A, Luneva NP, Geacintov NE. The Kinetic Deuterium Isotope Effect as a Probe of a Proton Coupled Electron Transfer Mechanism in the Oxidation of Guanine by 2-Aminopurine Radicals Journal of Physical Chemistry B. 104: 137-139.  1
1999 Wu J, Gu L, Wang H, Geacintov NE, Li GM. Mismatch repair processing of carcinogen-DNA adducts triggers apoptosis Molecular and Cellular Biology. 19: 8292-8301. PMID 10567554  1
1999 Rechkoblit O, Amin S, Geacintov NE. Primer length dependence of binding of DNA polymerase I Klenow fragment to template-primer complexes containing site-specific bulky lesions Biochemistry. 38: 11834-11843. PMID 10512640 DOI: 10.1021/bi990614k  1
1999 Xie XM, Geacintov NE, Broyde S. Origins of conformational differences between cis and trans DNA adducts derived from enantiomeric anti-benzo[a]pyrene diol epoxides. Chemical Research in Toxicology. 12: 597-609. PMID 10409399 DOI: 10.1021/tx990021a  1
1999 Xie XM, Geacintov NE, Broyde S. Stereochemical origin of opposite orientations in DNA adducts derived from enantiomeric anti-benzo[a]pyrene diol epoxides with different tumorigenic potentials. Biochemistry. 38: 2956-68. PMID 10074348 DOI: 10.1021/bi9825605  1
1999 Shukla R, Geacintov NE, Loechler EL. The major, N2-dG adduct of (+)-anti-B[a]PDE induces G→A mutations in a 5'-AGA-3' sequence context Carcinogenesis. 20: 261-268. PMID 10069463 DOI: 10.1093/carcin/20.2.261  1
1999 Shafirovich V, Dourandin A, Huang W, Luneva NP, Geacintov NE. Oxidation of Guanine at a Distance in Oligonucleotides Induced by Two-Photon Photoionization of 2-Aminopurine Journal of Physical Chemistry B. 103: 10924-10933.  1
1998 Kochevar IE, Garcia C, Geacintov NE. Photoaddition to DNA by Nonintercalated Chlorpromazine Molecules Photochemistry and Photobiology. 68: 692-697. PMID 9825699  1
1998 Tsao H, Mao B, Zhuang P, Xu R, Amin S, Geacintov NE. Sequence dependence and characteristics of bends induced by site-specific polynuclear aromatic carcinogen-deoxyguanosine lesions in oligonucleotides. Biochemistry. 37: 4993-5000. PMID 9538018 DOI: 10.1021/bi980291c  0.56
1998 Xu R, Mao B, Amin S, Geacintov NE. Bending and circularization of site-specific and stereoisomeric carcinogen-DNA adducts Biochemistry. 37: 769-778. PMID 9425101 DOI: 10.1021/bi971785x  1
1997 Hess MT, Gunz D, Luneva N, Geacintov NE, Naegeli H. Base pair conformation-dependent excision of benzo[a]pyrene diol epoxide-guanine adducts by human nucleotide excision repair enzymes. Molecular and Cellular Biology. 17: 7069-76. PMID 9372938  1
1997 Shukla R, Jelinsky S, Liu T, Geacintov NE, Loechler EL. How stereochemistry affects mutagenesis by N2-deoxyguanosine adducts of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene: Configuration of the adduct bond is more important than those of the hydroxyl groups Biochemistry. 36: 13263-13269. PMID 9341216 DOI: 10.1021/bi971195z  1
1997 Zhang YJ, Geacintov NE, Santella RM. Development of a monoclonal antibody recognizing benzo[c]phenanthrenediol epoxide-DNA adducts: Application to immunohistochemical detection of DNA damage Chemical Research in Toxicology. 10: 948-952. PMID 9305575 DOI: 10.1021/tx970050q  1
1997 Shukla R, Liu T, Geacintov NE, Loechler EL. The major, N2-dG adduct of (+)-anti-B[a]PDE shows a dramatically different mutagenic specificity (predominantly, G → a) in a 5'-CGT-3' sequence context Biochemistry. 36: 10256-10261. PMID 9254624 DOI: 10.1021/bi970541+  1
1997 Shafirovich VY, Dourandin A, Luneva NP, Geacintov NE. Migration and trapping of photoinjected excess electrons in double-stranded B-form DNA but not in single-stranded DNA Journal of Physical Chemistry B. 101: 5863-5868.  1
1996 Choi DJ, Roth RB, Liu T, Geacintov NE, Scicchitano DA. Incorrect base insertion and prematurely terminated transcripts during T7 RNA polymerase transcription elongation past benzo[a]pyrenediol epoxide-modified DNA Journal of Molecular Biology. 264: 213-219. PMID 8951371 DOI: 10.1006/jmbi.1996.0635  1
1996 Xu R, Dwarakanath S, Cosman M, Amin S, Geacintov NE. Site-specific adducts derived from the binding of anti-5-methylchrysene diol epoxide enantiomers to DNA: Synthesis and characteristics Carcinogenesis. 17: 2035-2042. PMID 8824532  1
1995 Cosman M, Hingerty BE, Geacintov NE, Broyde S, Patel DJ. Structural alignments of (+)- and (-)-trans-anti-benzo[a]pyrene-dG adducts positioned at a DNA template-primer junction. Biochemistry. 34: 15334-50. PMID 7578150 DOI: 10.1021/bi00046a043  1
1995 Jelinsky SA, Liu T, Geacintov NE, Loechler EL. The major, N2-gua adduct of the (+)-anti-benzo[a]pyrene diol epoxide is capable of inducing G→A and G→C, in addition to G→T, mutations Biochemistry. 34: 13545-13553. PMID 7577943  1
1995 Shafirovich VY, Courtney SH, Ya N, Geacintov NE. Proton-coupled photoinduced electron transfer, deuterium isotope effects, and fluorescence quenching in noncovalent benzo[a]pyrenetetraol-nucleoside complexes in aqueous solutions Journal of the American Chemical Society. 117: 4920-4929.  1
1995 Zou Y, Liu TM, Geacintov NE, Van Houten B. Interaction of the UvrABC nuclease system with a DNA duplex containing a single stereoisomer of dG-(+)- Or dG-(-)-anti-BPDE Biochemistry. 34: 13582-13593.  1
1994 Choi DJ, Marino-Alessandri DJ, Geacintov NE, Scicchitano DA. Site-specific benzo[a]pyrene diol epoxide-DNA adducts inhibit transcription elongation by bacteriophage T7 RNA polymerase Biochemistry. 33: 780-787. PMID 8292606  1
1994 Shafirovich VY, Kuzmin VA, Geacintov NE. Magnetic field effect on triplet formation as a probe of intersystem crossing mechanisms in benzo [a] pyrene diol epoxide derivative-guanosine complexes and covalent adducts Chemical Physics Letters. 222: 185-190. DOI: 10.1016/0009-2614(94)00302-5  1
1994 O'Connor D, Shafirovich VY, Geacintov NE. Influence of adduct stereochemistry and hydrogen-bonding solvents on photoinduced charge transfer in a covalent benzo[a]pyrene diol epoxide-nucleoside adduct on picosecond time scales Journal of Physical Chemistry. 98: 9831-9839.  1
1993 Margulis LA, Ibanez V, Geacintov NE. Base-sequence dependence of covalent binding of benzo[a]pyrene diol epoxide to guanine in oligodeoxyribonucleotides Chemical Research in Toxicology. 6: 59-63. PMID 8448351 DOI: 10.1021/tx00031a009  1
1993 Geacintov NE. Tracing charge separation events in photosynthesis: anomalous photovoltage polarity events explained Biophysical Journal. 65: 11-12. PMID 8369419  1
1993 Geacintov NE. Opposite stereoselective resistance to digestion by phosphodiesterases I and II of benzo[a]pyrene diol epoxide-modified oligonucleotide adducts Biochemistry®. 32: 11785-11793. PMID 8218249  1
1992 France LL, Geacintov NE, Breton J, Valkunas L. The dependence of the degrees of sigmoidicities of fluorescence induction curves in spinach chloroplasts on the duration of actinic pulses in pump-probe experiments Biochimica Et Biophysica Acta (Bba)/Protein Structure and Molecular. 1101. DOI: 10.1016/0167-4838(92)90474-R  1
1992 Valkunas L, Geacintov NE, France LL. Fluorescence induction in green plants revisited origin of variabilities in sigmoidicities on different time scales of irradiation Journal of Luminescence. 51: 67-78. DOI: 10.1016/0022-2313(92)90019-6  1
1991 Swenberg CE, Birke S, Geacintov NE. Characterization of the interaction of the radioprotector 1-methyl-2-[2-(methylthio)-2-piperidinovinyl]quinolinium iodide with supercoiled DNA Radiation Research. 127: 138-145. PMID 1946996  1
1991 Singh SB, Hingerty BE, Singh UC, Greenberg JP, Geacintov NE, Broyde S. Structures of the (+)- and (-)-trans-7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyre ne adducts to guanine-N2 in a duplex dodecamer. Cancer Research. 51: 3482-92. PMID 1905197  1
1991 Geacintov NE, Swenberg CE. Chemical, molecular biology, and genetic techniques for correlating DNA base damage induced by ionizing radiation with biological end points Basic Life Sciences. 58: 453-473; discussion . PMID 1811481  1
1991 Valkunas L, Geacintov NE, France L, Breton J. The dependence of the shapes of fluorescence induction curves in chloroplasts on the duration of illumination pulses Biophysical Journal. 59: 397-408.  1
1990 Swenberg CE, Carberry SE, Geacintov NE. Linear dichroism characteristics of ethidium- and proflavine-supercoiled DNA complexes Biopolymers. 29: 1735-1744. PMID 2145043 DOI: 10.1002/bip.360291406  1
1990 Jankowiak R, Lu PQ, Small GJ, Geacintov NE. Laser spectroscopic studies of DNA adduct structure types from enantiomeric diol epoxides of benzo[a]pyrene Chemical Research in Toxicology. 3: 39-46. PMID 2131823  1
1990 Cosman M, Ibanez V, Geacintov NE, Harvey RG. Preparation and isolation of adducts in high yield derived from the binding of two benzo[a]pyrene-7,8-dihydroxy-9,10-oxide stereoisomers to the oligonucleotide d(atatgtata) Carcinogenesis. 11: 1667-1672. PMID 2119261 DOI: 10.1093/carcin/11.9.1667  1
1990 Zielinski M, Pope M, Wang N, Horvath C, Geacintov NE. Photoemission from adenine crystal: Solvation of a pre-ionizing state Chemical Physics Letters. 165: 297-301. DOI: 10.1016/0009-2614(90)87192-T  1
1990 Pope M, Mao B, Steigman J, Geacintov NE. Electrolysis at an anthracene crystal/aqueous NO3- solution interface: The role of crystal defects Journal of Physical Chemistry. 94: 1719-1720.  1
1989 Carberry SE, Geacintov NE, Harvey RG. Reactions of stereoisomeric non-bay-region benz[a]anthracene diol epoxides with DNA and conformations of non-covalent complexes and covalent adducts Carcinogenesis. 10: 97-103. PMID 2910537 DOI: 10.1093/carcin/10.1.97  1
1989 Geacintov NE, Brenner HC. The triplet state as a probe of dynamics and structure in biological macromolecules. Photochemistry and Photobiology. 50: 841-858. PMID 2696992  1
1989 Kim SK, Geacintov NE, Zinger D, Sutherland JC. Fluorescence spectral characteristics and fluorescence decay profiles of covalent polycyclic aromatic carcinogen-DNA adducts Basic Life Sciences. 51: 187-205. PMID 2510712  1
1989 Roche CJ, Geacintov NE, Ibanez V, Harvey RG. Linear dichroism properties and orientations of different ultraviolet transition moments of benzo[a]pyrene derivatives bound noncovalently and cova Biophysical Chemistry. 33: 277-288. PMID 2508781 DOI: 10.1016/0301-4622(89)80029-8  1
1989 Kim SK, Brenner HC, Soh BJ, Geacintov NE. Fluorescence spectroscopy of benzo[a]pyrene diol epoxide-DNA adducts. Conformation-specific emission spectra. Photochemistry and Photobiology. 50: 327-337. PMID 2506585  1
1989 Kim SK, Geacintov NE, Brenner HC, Harvey RG. Identification of conformationally different binding sites in benzo[a]pyrene diol epoxide - DNA adducts by low-temperature fluorescence spectroscopy Carcinogenesis. 10: 1333-1335. PMID 2500269 DOI: 10.1093/carcin/10.7.1333  1
1988 Carberry SE, Shahbaz M, Geacintov NE, Harvey RG. Reactions of stereoisomeric and structurally related bay region diol epoxide derivatives of benz[a]anthracene with DNA. Conformations of non-covalent complexes and covalent carcinogen-DNA adducts Chemico-Biological Interactions. 66: 121-145. PMID 3383284 DOI: 10.1016/0009-2797(88)90046-4  1
1988 Zinger D, Geacintov NE. Acrylamide and molecular oxygen fluorescence quenching as a probe of solvent-accessibility of aromatic fluorophores complexed with DNA in relation to their conformations: coronene-DNA and other complexes Photochemistry and Photobiology. 47: 181-188. PMID 3344287  1
1988 Geacintov NE, Shahbaz M, Ibanez V, Moussaoui K, Harvey RG. Base-sequence dependence of noncovalent complex formation and reactivity of benzo[a]pyrene diol epoxide with polynucleotides Biochemistry. 27: 8380-8387. PMID 3149504  1
1988 Harvey RG, Geacintov NE. Intercalation and binding of carcinogenic hydrocarbon metabolites to nucleic acids Accounts of Chemical Research. 21: 66-73.  1
1987 Geacintov NE. Orientation and linear dichroism characteristics of porphyrin-DNA complexes Biochemistry. 26: 3087-3092. PMID 3607012  1
1987 Vigny P, Blais J, Ibanez V, Geacintov NE. A flow linear dichroism study of the orientation of 4',5'-psoralen-DNA photoadducts Photochemistry and Photobiology. 45: 601-607. PMID 3602111  1
1987 Geacintov NE. Principles and applications of fluorescence techniques in biophysical chemistry Photochemistry and Photobiology. 45: 547-553. PMID 3575446  1
1987 Zinger D, Geacintov NE, Harvey RG. Conformations and selective photodissociation of heterogeneous benzo(a)pyrene diol epoxide enantiomer-DNA adducts Biophysical Chemistry. 27: 131-138. PMID 3117127 DOI: 10.1016/0301-4622(87)80053-4  1
1987 Kolubayev V, Brenner HC, Geacintov NE. Stereoselective covalent binding of enantiomers of anti-benzo[a]pyrene diol epoxide to DNA as probed by optical detection of magnetic resonance Biochemistry. 26: 2638-2641. PMID 3111532  1
1987 Yoshida H, Swenberg CE, Geacintov NE. Kinetic flow dichroism study of conformational changes in supercoiled DNA induced by ethidium bromide and noncovalent and covalent binding of benzo[a]pyrene diol epoxide Biochemistry. 26: 1351-1358. PMID 2952167  1
1987 Geacintov NE, Breton J, Knox RS. Energy transfer and fluorescence mechanisms in photosynthetic membranes Critical Reviews in Plant Sciences. 5: 1-44. DOI: 10.1080/07352688709382233  1
1986 Geacintov NE, Breton J, Knox RS. Energy migration and exciton trapping in green plant photosynthesis. Photosynthesis Research. 10: 233-42. PMID 24435370 DOI: 10.1007/BF00118288  1
1986 Kim MH, Geacintov NE, Mcquillen DG, Pope M, Harvey RG. Reaction mechanisms of trans-9,10-dihydroxy-anti-7,8-epoxy-7,8,9,10-tetrahydro-3-methylcholanthrene with DNA in aqueous solutions. conformation of adducts Carcinogenesis. 7: 41-47. PMID 3943143 DOI: 10.1093/carcin/7.1.41  1
1986 Geacintov NE. Is intercalation a critical factor in the covalent binding of mutagenic and tumorigenic polycyclic aromatic diol epoxides to dna? Carcinogenesis. 7: 759-766. PMID 3698204 DOI: 10.1093/carcin/7.5.759  1
1986 Shahbaz M, Geacintov NE, Harvey RG. Noncovalent intercalative complex formation and kinetic flow linear dichroism of racemic syn- and anti-benzo[a]pyrenediol epoxide-DNA solutions Biochemistry. 25: 3290-3296. PMID 3089275  1
1986 Gagliano AG, Breton J, Geacintov NE. Electric linear dichroism of chromatophores, pigment-protein and reaction center complexes derived from Rhodopseudomonas spheroides Photobiochemistry and Photobiophysics. 10: 213-221.  1
1985 Moussaoui K, Geacintov NE, Harvey RG. Reactivity and binding of benzo(a)pyrene diol epoxide to poly(dG-dC)·(dG-dC) and poly(dG-m5dC)·(dg-m5dC) in the B and Z forms Biophysical Chemistry. 22: 285-297. PMID 3933587 DOI: 10.1016/0301-4622(85)80052-1  1
1985 Roche CJ, Zinger D, Geacintov NE, Harvey RG. Enhancement of stability of 7 beta,8 alpha-dihyroxy-9 alpha epoxybenzo(a)pyrene by complex formation with serum albumin Cancer Biochemistry Biophysics. 8: 35-40. PMID 3928138  1
1985 Gagliano AG, Hoarau J, Breton J, Geacintov NE. Orientation of pigments in phycobilisomes of Porphyridium sp. Lewin. A linear dichroism study utilizing electric and gel orientation methods Bba - Bioenergetics. 808: 455-463. DOI: 10.1016/0005-2728(85)90154-9  1
1985 Dobek A, Deprez J, Geacintov NE, Paillotin G, Breton J. Chlorophyll fluorescence phenomena in chloroplasts on subnanosecond time-scales probed by picosecond pulse pairs Bba - Bioenergetics. 806: 81-92. DOI: 10.1016/0005-2728(85)90084-2  1
1985 Kolubayev T, Geacintov NE, Paillotin G, Breton J. Domain sizes in chloroplasts and chlorophyll-protein complexes probed by fluorescence yield quenching induced by singlet-triplet exciton annihilation Bba - Bioenergetics. 808: 66-76. DOI: 10.1016/0005-2728(85)90028-3  1
1985 Geacintov NE, Kim MH, Moussaoui K. Conformations of non-covalent and covalent polycyclic aromatic diol epoxide-nucleic acid complexes Proceedings of the American Association For Cancer Research 1
1984 Kim MH, Geacintov NE, Pope M, Harvey RG. Structural effects in reactivity and adduct formation of polycyclic aromatic epoxide and diol epoxide derivatives with DNA: Comparison between 1-oxiranylpyrene and benzo[a]pyrenediol epoxide Biochemistry. 23: 5433-5439. PMID 6439240  1
1984 Geacintov NE, Hibshoosh H, Ibanez V, Benjamin MJ, Harvey RG. Mechanisms of reaction of benzo(a)pyrene-7,8-diol-9,10-epoxide with DNA in aqueous solutions Biophysical Chemistry. 20: 121-133. PMID 6435696 DOI: 10.1016/0301-4622(84)80012-5  1
1983 Paillotin G, Geacintov NE, Breton J. A master equation theory of fluorescence induction, photochemical yield, and singlet-triplet exciton quenching in photosynthetic systems Biophysical Journal. 44: 65-77. PMID 6626680  1
1983 Deprez J, Dobek A, Geacintov NE, Paillotin G, Breton J. Probing fluorescence induction in chloroplasts on a nanosecond time scale utilizing picosecond laser pulse pairs Bba - Bioenergetics. 725: 444-454. DOI: 10.1016/0005-2728(83)90185-8  1
1982 Geacintov NE, Gagliano AG, Ibanez V, Harvey RG. Spectroscopic characterizations and comparisons of the structures of the covalent adducts derived from the reactions of 7,8-dihydroxy-7,8,9,10-tetrahydrobenzo [a]pyrene-9,10-oxide, and the 9,10-epoxides of 7,8,9,10-tetrahydrobenzo[a]pyrene and 9,10,11,12-tetrahydrobenzo[e]pyrene with DNA Carcinogenesis. 3: 247-253. PMID 7083468 DOI: 10.1093/carcin/3.3.247  1
1982 Waldmeyer J, Korkidis K, Geacintov NE. Relative contributions of tryptophan and tyrosine to the phosphorescence emission of human serum albumin at low temperatures Photochemistry and Photobiology. 35: 299-304. PMID 7063549  1
1982 Poulos AT, Kuzmin V, Geacintov NE. Probing the microenvironmental of benzo[a]pyrene diol epoxide-DNA adducts by triplet excited state quenching methods Journal of Biochemical and Biophysical Methods. 6: 269-281. PMID 6815256 DOI: 10.1016/0165-022X(82)90009-4  1
1982 Geacintov NE, Yoshida H, Ibanez V, Harvey RG. Noncovalent binding of 7β,8α-dihydroxy-9α, 10α-epoxytetrahydrobenzo[a]pyrene to deoxyribonucleic acid and its catalytic effect on the hydrolysis of the diol epoxide to tetrol Biochemistry. 21: 1864-1869. PMID 6805508  1
1982 Geacintov NE, Hibshoosh H, Ibanez V. Mechanisms of covalent binding of benzo(a)pyrene diol epoxide to DNA Proceedings of the American Association For Cancer Research 1
1981 Geacintov NE, Yoshida H, Ibanez V, Harvey RG. Non-covalent intercalative binding of 7,8-dihydroxy-9,10-epoxybenzo(a)pyrene to DNA Biochemical and Biophysical Research Communications. 100: 1569-1577. PMID 6794569 DOI: 10.1016/0006-291X(81)90698-7  1
1981 Geacintov NE, Ibanez V, Yoshida H. Stopped-flow kinetic studies of the interaction of benzo(a)pyrene diol epoxide with DNA Proceedings of the American Association For Cancer Research. 328.  1
1981 Geacintov NE, Ibanez V, Yoshida H. Mechanisms of interaction of benzo(a)pyrene diol epoxide and related compounds with DNA conformation of adducts Journal of Supramolecular and Cellular Biochemistry. 15.  1
1981 Geacintov NE, Waldmeyer J, Kuzmin VA, Kolubayev T. Dynamics of the binding of acridine dyes to DNA investigated by triplet excited state probe techniques Journal of Physical Chemistry. 85: 3608-3613.  1
1980 Breton J, Geacintov NE. Picosecond fluorescence kinetics and fast energy transfer processes in photosynthetic membranes Bba Reviews On Bioenergetics. 594: 1-32. PMID 7006696 DOI: 10.1016/0304-4173(80)90011-7  1
1979 Prusik T, Geacintov NE. Fluorescence properties of a benzo(a)pyrene 7,8 dihydrodiol 9,10-oxide-DNA adduct. Conformation and effects of intermolecular DNA interactions Biochemical and Biophysical Research Communications. 88: 782-790. PMID 572681 DOI: 10.1016/0006-291X(79)91476-1  1
1979 Breton J, Geacintov NE, Swenberg CE. Quenching of fluorescence by triplet excited states in chloroplasts Bba - Bioenergetics. 548: 616-635. PMID 508739 DOI: 10.1016/0005-2728(79)90069-0  1
1979 Prusik T, Geacintov NE, Tobiasz C, Ivanovic V, Weinstein IB. Fluorescence study of the physico-chemical properties of a benzo(a)pyrene 7,8-dihydrodiol 9,10-oxide derivative bound covalently to DNA Photochemistry and Photobiology. 29: 223-232. PMID 482375  1
1979 Paillotin G, Swenberg CE, Breton J, Geacintov NE. Analysis of picosecond laser-induced fluorescence phenomena in photosynthetic membranes utilizing a master equation approach Biophysical Journal. 25: 513-533. PMID 262402  1
1978 Becker JF, Geacintov NE, Swenberg CE. Photovoltages in suspensions of magnetically oriented chloroplasts Bba - Bioenergetics. 503: 545-554. PMID 687614 DOI: 10.1016/0005-2728(78)90152-4  1
1978 Whitten WB, Pearlstein RM, Phares EF, Geacintov NE. Linear dichroism of electric field oriented bacteriochlorophyll a-protein from green photosynthetic bacteria Bba - Bioenergetics. 503: 491-498. PMID 687613 DOI: 10.1016/0005-2728(78)90148-2  1
1978 Ivanovic V, Geacintov NE, Yamasaki H, Weinstein IB. DNA and RNA adducts formed in hamster embryo cell cultures exposed to benzo[a]pyrene Biochemistry. 17: 1597-1603. PMID 656393  1
1978 Becker JF, Trentacosti F, Geacintov NE. A linear dichroism study of the orientation of aromatic protein residues in magnetically oriented bovine rod outer segments Photochemistry and Photobiology. 27: 51-54. PMID 625493  1
1978 Geacintov NE. Electric linear dichroism study on the orientation of benzo[a]pyrene-7,8-dihydrodiol 9,10-oxide covalently bound to DNA Biochemistry. 17: 5256-5262. PMID 569497  1
1978 Geacintov NE, Prusik T. Spectroscopic studies of carcinogen-DNA complexes. Structure of the covalent benzo(a)pyrene 7,8-dihydrodiol 9,10-oxide-DNA adduct Proceedings of the American Association For Cancer Research 1
1978 Ivanovic V, Geacintov NE, Prusik T. Spectroscopic techniques for investigation of carcinogen-DNA complexes. Conformation of the covalent benzo(a)pyrene (BP) 7,8-dihydrodiol 9,10-oxide-DNA adduct Federation Proceedings. 37.  1
1977 Gagliano AG, Geacintov NE, Breton J. Orientation and linear dichroism of chloroplasts and sub-chloroplast fragments oriented in an electric field Bba - Bioenergetics. 461: 460-474. PMID 901776 DOI: 10.1016/0005-2728(77)90233-X  1
1977 Geacintov NE, Breton J. Exciton annihilation in the two photosystems in chloroplasts at 100°K Biophysical Journal. 17: 1-15. PMID 831854  1
1977 Campillo AJ, Shapiro SL, Geacintov NE, Swenberg CE. Single-pulse picosecond determination of 735 nm fluorescence risetime in spinach chloroplasts. Febs Letters. 83: 316-20. PMID 590508 DOI: 10.1016/0014-5793(77)81031-4  1
1977 Binder M, Geacintov NE, Pope M, Swenberg CE. MAGNETIC FIELD MODULATED SCINTILLATION FROM TETRACENE-DOPED ANTHRACENE CRYSTALS UNDER alpha -PARTICLE IRRADIATION Physica Status Solidi (a) Applied Research. 10: 621-628.  1
1976 Swenberg CE, Dominijanni R, Geacintov NE. Effects of pigment heterogeneity on fluorescence in photosynthetic units Photochemistry and Photobiology. 24: 601-604. PMID 1019251  1
1976 Prusik T, Geacintov NE. Triplets of aromatic dyes bound to DNA as probes of the mobility of DNA-bound metal ions Febs Letters. 71: 236-240. PMID 1001442 DOI: 10.1016/0014-5793(76)80940-4  1
1976 Breton J, Geacintov NE. Quenching of fluorescence of chlorophyll in vivo by long-lived excited states Febs Letters. 69: 86-89. PMID 992048 DOI: 10.1016/0014-5793(76)80659-X  1
1976 Geacintov NE, Prusik T, Khosrofian JM. Properties of benzopyrene-DNA complexes investigated by fluorescence and triplet flash photolysis techniques Journal of the American Chemical Society. 98: 6444-6452. PMID 972216  1
1976 Becker JF, Breton J, Geacintov NE, Trentacosti F. Anisotropy of photosynthetic membranes and the degree of fluorescence polarization Bba - Bioenergetics. 440: 531-544. PMID 963043 DOI: 10.1016/0005-2728(76)90040-2  1
1976 Ivanovic V, Geacintov NE, Weinstein IB. Cellular binding of benzo(a)pyrene to DNA characterized by low temperature fluorescence Biochemical and Biophysical Research Communications. 70: 1172-1179. PMID 942439 DOI: 10.1016/0006-291X(76)91026-3  1
1975 Geacintov NE, Flamer TJ, Prusik T, Khosrofian JM. Triplet excited states of polycyclic aromatic compounds as probes of their microenvironment in serum albumin complexes Biochemical and Biophysical Research Communications. 64: 1245-1252. PMID 49184 DOI: 10.1016/0006-291X(75)90826-8  1
1975 Geacintov NE, Binder M, Swenberg CE, Pope M. Exciton dynamics in -particle tracks in organic crystals: Magnetic field study of the scintillation in tetracene crystals Physical Review B. 12: 4113-4134. DOI: 10.1103/PhysRevB.12.4113  1
1975 Geacintov NE. Interaction of air pollutant carcinogens with living cells, nucleic acids, and proteins Bulletin of the New York Academy of Medicine: Journal of Urban Health. 51: 1158.  1
1975 Swenberg CE, Markevich D, Geacintov NE, Pope M. ROOM TEMPERATURE ELECTRON DRIFT MOBILITIES IN 1,4-DIBROMONAPHTHALENE Physica Status Solidi (a) Applied Research. 29: 651-657.  1
1974 Geacintov NE, Van Nostrand F, Becker JF. Polarized light spectroscopy of photosynthetic membranes in magneto-oriented whole cells and chloroplasts. Fluorescence and dichroism Bba - Bioenergetics. 347: 443-463. PMID 4210309 DOI: 10.1016/0005-2728(74)90082-6  1
1974 Benson R, Geacintov NE. Deuterium effect on the quenching of aromatic hydrocarbon triplet excited states by oxygen The Journal of Chemical Physics. 60: 3251-3257.  1
1974 Swenberg CE, Ratner MA, Geacintov NE. Energy dependence of optically induced exciton fission The Journal of Chemical Physics. 60: 2158-2162.  1
1973 Breton J, Becker JF, Geacintov NE. Fluorescence depolarization study of randomly oriented and magneto-oriented spinach chloroplasts in suspension Biochemical and Biophysical Research Communications. 54: 1403-1409. PMID 4754718 DOI: 10.1016/0006-291X(73)91142-X  1
1973 Becker JF, Geacintov NE, Van Nostrand F, Van Metter R. Orientation of chlorophyll in vivo. Studies with magnetic field oriented Chlorella Biochemical and Biophysical Research Communications. 51: 597-602. PMID 4704050 DOI: 10.1016/0006-291X(73)91356-9  1
1973 Benson R, Geacintov NE. Quenching of excited triplets of aromatic hydrocarbons by molecular oxygen Journal of Chemical Physics. 59: 4428-4434. DOI: 10.1063/1.1680642  1
1973 Vogel F, Geacintov NE, Pope M. Photoinjection of holes into anthracene crystals using aqueous I3- solutions: Magnetic field effects Journal of the Chemical Society, Faraday Transactions 2: Molecular and Chemical Physics. 69: 1208-1222. DOI: 10.1039/F29736901208  1
1972 Geacintov NE, Van Nostrand F, Becker JF, Tinkel JB. Magnetic field induced orientation of photosynthetic systems Bba - Bioenergetics. 267: 65-79. PMID 5019475 DOI: 10.1016/0005-2728(72)90138-7  1
1972 Geacintov NE, Benson R, Pomeranz SB. Interaction of triplets or aromatic hydrocarbons with oxygen and nitric oxide Chemical Physics Letters. 17: 280-282. DOI: 10.1016/0009-2614(72)87074-X  1
1972 Geacintov NE, Swenberg CE. Possible effects of magnetic fields on the quenching of triplet excited states of polynuclear hydrocarbons by oxygen The Journal of Chemical Physics. 57: 389-398.  1
1971 Geacintov NE, van Nostrand F, Pope M, Tinkel JB. Magnetic field effect on the chlorophyll fluorescence in Chlorella Bba - Bioenergetics. 226: 486-491. PMID 5575169 DOI: 10.1016/0005-2728(71)90118-6  1
1971 Geacintov NE, Burgos J, Pope M, Strom C. Heterofission of pentacene excited singlets in pentacene-doped tetracene crystals Chemical Physics Letters. 11: 504-508. DOI: 10.1016/0009-2614(71)80395-0  1
1970 Geacintov NE, Pope M, Fox S. Magnetic field effects on photo-enhanced currents in organic crystals Journal of Physics and Chemistry of Solids. 31: 1375-1379. DOI: 10.1016/0022-3697(70)90141-1  1
1970 Pope M, Geacintov NE, Saperstein D, Vogel F. Calculation of the diffusion length, diffusion coefficient and lifetime of triplet excitons in crystalline tetracene Journal of Luminescence. 1: 224-230. DOI: 10.1016/0022-2313(70)90037-2  1
1969 Geacintov NE, Pope M. Intrinsic photoconductivity in organic crystals Solid State Communications. 7.  1
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