Gary C. Pien, Ph.D. - Publications

Affiliations: 
2002 Brown University, Providence, RI 
Area:
Immunology, Microbiology Biology

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Hui DJ, Edmonson SC, Podsakoff GM, Pien GC, Ivanciu L, Camire RM, Ertl H, Mingozzi F, High KA, Basner-Tschakarjan E. AAV capsid CD8+ T-cell epitopes are highly conserved across AAV serotypes. Molecular Therapy. Methods & Clinical Development. 2: 15029. PMID 26445723 DOI: 10.1038/Mtm.2015.29  0.439
2013 Hui DJ, Basner-Tschakarjan E, Chen Y, Davidson RJ, Buchlis G, Yazicioglu M, Pien GC, Finn JD, Haurigot V, Tai A, Scott DW, Cousens LP, Zhou S, De Groot AS, Mingozzi F. Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopes. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1727-37. PMID 23857231 DOI: 10.1038/Mt.2013.166  0.452
2010 Finn JD, Hui D, Downey HD, Dunn D, Pien GC, Mingozzi F, Zhou S, High KA. Proteasome inhibitors decrease AAV2 capsid derived peptide epitope presentation on MHC class I following transduction. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 135-42. PMID 19904235 DOI: 10.1182/Blood.V114.22.695.695  0.407
2010 Hui DJ, Basner-Tschakarjan E, Pien GC, Martin WD, DeGroot AS, High KA, Mingozzi F. Peptide-Induced Antigen-Specific CD4+CD25+FoxP3+ T Cells Suppress Cytotoxicity T Cell Responses Directed Against the AAV Capsid. Blood. 116: 3769-3769. DOI: 10.1182/Blood.V116.21.3769.3769  0.456
2009 Pien GC, Basner-Tschakarjan E, Hui DJ, Mentlik AN, Finn JD, Hasbrouck NC, Zhou S, Murphy SL, Maus MV, Mingozzi F, Orange JS, High KA. Capsid antigen presentation flags human hepatocytes for destruction after transduction by adeno-associated viral vectors. The Journal of Clinical Investigation. 119: 1688-95. PMID 19436115 DOI: 10.1172/Jci36891  0.397
2009 Hui DJ, Pien GC, Basner-Tschakarjan E, Mingozzi F, Finn JD, Zhou S, Martin W, Groot ASD, High KA. Suppression of CTL Responses against AAV-Capsid Epitopes by Peptide-Induced Regulatory T Cells. Blood. 114: 377-377. DOI: 10.1182/Blood.V114.22.377.377  0.475
2007 Pien GC, Hasbrouck NC, Maus MV, Mingozzi F, High KA. Quantifying Capsid Peptide:MHC I Complexes Following Adeno-Associated Virus (AAV) Transduction Blood. 110: 3737-3737. DOI: 10.1182/Blood.V110.11.3737.3737  0.381
2006 Huang D, Shi FD, Jung S, Pien GC, Wang J, Salazar-Mather TP, He TT, Weaver JT, Ljunggren HG, Biron CA, Littman DR, Ransohoff RM. The neuronal chemokine CX3CL1/fractalkine selectively recruits NK cells that modify experimental autoimmune encephalomyelitis within the central nervous system. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 896-905. PMID 16675847 DOI: 10.1096/Fj.05-5465Com  0.62
2002 Pien GC, Nguyen KB, Malmgaard L, Satoskar AR, Biron CA. A unique mechanism for innate cytokine promotion of T cell responses to viral infections. Journal of Immunology (Baltimore, Md. : 1950). 169: 5827-37. PMID 12421964 DOI: 10.4049/Jimmunol.169.10.5827  0.767
2002 Nguyen KB, Watford WT, Salomon R, Hofmann SR, Pien GC, Morinobu A, Gadina M, O'Shea JJ, Biron CA. Critical role for STAT4 activation by type 1 interferons in the interferon-gamma response to viral infection. Science (New York, N.Y.). 297: 2063-6. PMID 12242445 DOI: 10.1126/Science.1074900  0.744
2002 Biron CA, Nguyen KB, Pien GC. Innate immune responses to LCMV infections: natural killer cells and cytokines. Current Topics in Microbiology and Immunology. 263: 7-27. PMID 11987821 DOI: 10.1007/978-3-642-56055-2_2  0.771
2001 Wu C, Nguyen KB, Pien GC, Wang N, Gullo C, Howie D, Sosa MR, Edwards MJ, Borrow P, Satoskar AR, Sharpe AH, Biron CA, Terhorst C. SAP controls T cell responses to virus and terminal differentiation of TH2 cells. Nature Immunology. 2: 410-4. PMID 11323694 DOI: 10.1038/87713  0.72
2000 Pien GC, Satoskar AR, Takeda K, Akira S, Biron CA. Cutting edge: selective IL-18 requirements for induction of compartmental IFN-gamma responses during viral infection. Journal of Immunology (Baltimore, Md. : 1950). 165: 4787-91. PMID 11046000 DOI: 10.4049/Jimmunol.165.9.4787  0.685
2000 Nguyen KB, Cousens LP, Doughty LA, Pien GC, Durbin JE, Biron CA. Interferon alpha/beta-mediated inhibition and promotion of interferon gamma: STAT1 resolves a paradox. Nature Immunology. 1: 70-6. PMID 10881178 DOI: 10.1038/76940  0.766
2000 Pien GC, Biron CA. Compartmental differences in NK cell responsiveness to IL-12 during lymphocytic choriomeningitis virus infection. Journal of Immunology (Baltimore, Md. : 1950). 164: 994-1001. PMID 10623849 DOI: 10.4049/Jimmunol.164.2.994  0.74
1999 Biron CA, Nguyen KB, Pien GC, Cousens LP, Salazar-Mather TP. Natural killer cells in antiviral defense: function and regulation by innate cytokines. Annual Review of Immunology. 17: 189-220. PMID 10358757 DOI: 10.1146/Annurev.Immunol.17.1.189  0.774
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