Babak Razani, Ph.D. - Publications

Affiliations: 
2003 Yeshiva University, New York, NY, United States 
Area:
Cell Biology, Molecular Biology, Animal Physiology Biology

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 He A, Chen X, Tan M, Chen Y, Lu D, Zhang X, Dean JM, Razani B, Lodhi IJ. Acetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation. Molecular Cell. PMID 32473093 DOI: 10.1016/J.Molcel.2020.05.007  0.33
2019 Evans TD, Zhang X, Jeong SJ, He A, Song E, Bhattacharya S, Holloway KB, Lodhi IJ, Razani B. TFEB drives PGC-1α expression in adipocytes to protect against diet-induced metabolic dysfunction. Science Signaling. 12. PMID 31690633 DOI: 10.1126/Scisignal.Aau2281  0.353
2019 Javaheri A, Bajpai G, Picataggi A, Mani S, Foroughi L, Evie H, Kovacs A, Weinheimer CJ, Hyrc K, Xiao Q, Ballabio A, Lee JM, Matkovich SJ, Razani B, Schilling JD, et al. TFEB activation in macrophages attenuates postmyocardial infarction ventricular dysfunction independently of ATG5-mediated autophagy. Jci Insight. 4. PMID 31672943 DOI: 10.1172/Jci.Insight.127312  0.346
2019 Kalugotla G, He L, Weber KJ, Daemen S, Reller A, Razani B, Schilling JD. Frontline Science: Acyl-CoA synthetase 1 exacerbates lipotoxic inflammasome activation in primary macrophages. Journal of Leukocyte Biology. PMID 31166619 DOI: 10.1002/Jlb.3Hi0219-045Rr  0.319
2018 Jeong SJ, Zhang X, Rodriguez-Velez A, Evans TD, Razani B. p62/SQSTM1 and Selective Autophagy in Cardiometabolic Diseases. Antioxidants & Redox Signaling. PMID 30588824 DOI: 10.1089/Ars.2018.7649  0.318
2018 Weber KJ, Sauer M, He L, Tycksen E, Kalugotla G, Razani B, Schilling JD. PPARγ Deficiency Suppresses the Release of IL-1β and IL-1α in Macrophages via a Type 1 IFN-Dependent Mechanism. Journal of Immunology (Baltimore, Md. : 1950). PMID 30143592 DOI: 10.4049/Jimmunol.1800224  0.336
2018 Zhang Y, Higgins CB, Mayer AL, Mysorekar IU, Razani BB, Graham MJ, Hruz PW, DeBosch BJ. TFEB-dependent Induction of Thermogenesis by the Hepatocyte SLC2A Inhibitor Trehalose. Autophagy. PMID 29996716 DOI: 10.1080/15548627.2018.1493044  0.347
2018 Evans TD, Jeong SJ, Zhang X, Razani B. TFEB and trehalose drive the macrophage autophagy-lysosome system to protect against atherosclerosis. Autophagy. 1-7. PMID 29394113 DOI: 10.1080/15548627.2018.1434373  0.37
2017 Zhang H, Shi J, Hachet MA, Xue C, Bauer RC, Jiang H, Li W, Tohyama J, Millar J, Billheimer J, Phillips MC, Razani B, Rader DJ, Reilly MP. CRISPR/Cas9-Mediated Gene Editing in Human iPSC-Derived Macrophage Reveals Lysosomal Acid Lipase Function in Human Macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28882870 DOI: 10.1161/Atvbaha.117.310023  0.302
2017 Liu H, Javaheri A, Godar RJ, Murphy J, Ma X, Rohatgi N, Mahadevan J, Hyrc K, Saftig P, Marshall C, McDaniel ML, Remedi MS, Razani B, Urano F, Diwan A. Intermittent Fasting Preserves Beta-Cell Mass in Obesity-induced Diabetes via the Autophagy-Lysosome Pathway. Autophagy. 0. PMID 28853981 DOI: 10.1080/15548627.2017.1368596  0.339
2017 Fang L, Hodge J, Saaoud F, Wang J, Iwanowycz S, Wang Y, Hui Y, Evans TD, Razani B, Fan D. Transcriptional factor EB regulates macrophage polarization in the tumor microenvironment. Oncoimmunology. 6: e1312042. PMID 28638736 DOI: 10.1080/2162402X.2017.1312042  0.316
2017 Sergin I, Evans TD, Zhang X, Bhattacharya S, Stokes CJ, Song E, Ali S, Dehestani B, Holloway KB, Micevych PS, Javaheri A, Crowley JR, Ballabio A, Schilling JD, Epelman S, ... ... Razani B, et al. Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis. Nature Communications. 8: 15750. PMID 28589926 DOI: 10.1038/Ncomms15750  0.335
2017 Evans TD, Sergin I, Zhang X, Razani B. Target acquired: Selective autophagy in cardiometabolic disease. Science Signaling. 10. PMID 28246200 DOI: 10.1126/Scisignal.Aag2298  0.323
2016 Evans TD, Sergin I, Zhang X, Razani B. Modulating Oxysterol Sensing to Control Macrophage Apoptosis and Atherosclerosis. Circulation Research. 119: 1258-1261. PMID 27932465 DOI: 10.1161/Circresaha.116.310155  0.357
2016 Leng S, Iwanowycz S, Saaoud F, Wang J, Wang Y, Sergin I, Razani B, Fan D. Ursolic acid enhances macrophage autophagy and attenuates atherogenesis. Journal of Lipid Research. PMID 27063951 DOI: 10.1194/Jlr.M065888  0.347
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Razani B, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886  0.395
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Razani B, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.602
2016 Sergin I, Bhattacharya S, Emanuel R, Esen E, Stokes CJ, Evans TD, Arif B, Curci JA, Razani B. Inclusion bodies enriched for p62 and polyubiquitinated proteins in macrophages protect against atherosclerosis. Science Signaling. 9: ra2. PMID 26732762 DOI: 10.1126/Scisignal.Aad5614  0.378
2015 Sergin I, Evans TD, Razani B. Degradation and beyond: the macrophage lysosome as a nexus for nutrient sensing and processing in atherosclerosis. Current Opinion in Lipidology. 26: 394-404. PMID 26241101 DOI: 10.1097/Mol.0000000000000213  0.304
2015 Razani B, Raines EW. Can the DNA damage response be harnessed to modulate atherosclerotic plaque phenotype? Circulation Research. 116: 770-3. PMID 25722437 DOI: 10.1161/Circresaha.115.305922  0.301
2014 Sergin I, Evans TD, Bhattacharya S, Razani B. Hypoxia in plaque macrophages: a new danger signal for interleukin-1β activation? Circulation Research. 115: 817-20. PMID 25342768 DOI: 10.1161/Circresaha.114.305197  0.319
2014 Emanuel R, Sergin I, Bhattacharya S, Turner JN, Epelman S, Settembre C, Diwan A, Ballabio A, Razani B. Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelae. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1942-52. PMID 25060788 DOI: 10.1161/Atvbaha.114.303342  0.396
2014 Sergin I, Razani B. Self-eating in the plaque: what macrophage autophagy reveals about atherosclerosis. Trends in Endocrinology and Metabolism: Tem. 25: 225-34. PMID 24746519 DOI: 10.1016/J.Tem.2014.03.010  0.305
2012 Lodhi IJ, Yin L, Jensen-Urstad AP, Funai K, Coleman T, Baird JH, El Ramahi MK, Razani B, Song H, Fu-Hsu F, Turk J, Semenkovich CF. Inhibiting adipose tissue lipogenesis reprograms thermogenesis and PPARγ activation to decrease diet-induced obesity. Cell Metabolism. 16: 189-201. PMID 22863804 DOI: 10.1016/J.Cmet.2012.06.013  0.363
2012 Lei Y, Wen H, Yu Y, Taxman DJ, Zhang L, Widman DG, Swanson KV, Wen KW, Damania B, Moore CB, Giguère PM, Siderovski DP, Hiscott J, Razani B, Semenkovich CF, et al. The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. Immunity. 36: 933-46. PMID 22749352 DOI: 10.1016/J.Immuni.2012.03.025  0.324
2012 Razani B, Feng C, Coleman T, Emanuel R, Wen H, Hwang S, Ting JP, Virgin HW, Kastan MB, Semenkovich CF. Autophagy links inflammasomes to atherosclerotic progression. Cell Metabolism. 15: 534-44. PMID 22440612 DOI: 10.1016/J.Cmet.2012.02.011  0.374
2011 Razani B, Zhang H, Schulze PC, Schilling JD, Verbsky J, Lodhi IJ, Topkara VK, Feng C, Coleman T, Kovacs A, Kelly DP, Saffitz JE, Dorn GW, Nichols CG, Semenkovich CF. Fatty acid synthase modulates homeostatic responses to myocardial stress. The Journal of Biological Chemistry. 286: 30949-61. PMID 21757749 DOI: 10.1074/Jbc.M111.230508  0.361
2010 Razani B, Feng C, Semenkovich CF. p53 is required for chloroquine-induced atheroprotection but not insulin sensitization. Journal of Lipid Research. 51: 1738-46. PMID 20208057 DOI: 10.1194/Jlr.M003681  0.355
2004 Cohen AW, Razani B, Schubert W, Williams TM, Wang XB, Iyengar P, Brasaemle DL, Scherer PE, Lisanti MP. Role of caveolin-1 in the modulation of lipolysis and lipid droplet formation. Diabetes. 53: 1261-70. PMID 15111495 DOI: 10.2337/Diabetes.53.5.1261  0.768
2004 Williams TM, Lee H, Cheung MW, Cohen AW, Razani B, Iyengar P, Scherer PE, Pestell RG, Lisanti MP. Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia. The Journal of Biological Chemistry. 279: 24745-56. PMID 15044451 DOI: 10.1074/Jbc.M402064200  0.709
2003 Park DS, Cohen AW, Frank PG, Razani B, Lee H, Williams TM, Chandra M, Shirani J, De Souza AP, Tang B, Jelicks LA, Factor SM, Weiss LM, Tanowitz HB, Lisanti MP. Caveolin-1 null (-/-) mice show dramatic reductions in life span. Biochemistry. 42: 15124-31. PMID 14690422 DOI: 10.1021/Bi0356348  0.768
2003 Cohen AW, Razani B, Wang XB, Combs TP, Williams TM, Scherer PE, Lisanti MP. Caveolin-1-deficient mice show insulin resistance and defective insulin receptor protein expression in adipose tissue. American Journal of Physiology. Cell Physiology. 285: C222-35. PMID 12660144 DOI: 10.1152/Ajpcell.00006.2003  0.595
2003 Williams TM, Cheung MW, Park DS, Razani B, Cohen AW, Muller WJ, Di Vizio D, Chopra NG, Pestell RG, Lisanti MP. Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice. Molecular Biology of the Cell. 14: 1027-42. PMID 12631721 DOI: 10.1091/Mbc.E02-08-0503  0.621
2002 Park DS, Lee H, Frank PG, Razani B, Nguyen AV, Parlow AF, Russell RG, Hulit J, Pestell RG, Lisanti MP. Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade. Molecular Biology of the Cell. 13: 3416-30. PMID 12388746 DOI: 10.1091/Mbc.02-05-0071  0.747
2002 Lee H, Park DS, Razani B, Russell RG, Pestell RG, Lisanti MP. Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia. The American Journal of Pathology. 161: 1357-69. PMID 12368209 DOI: 10.1016/S0002-9440(10)64412-4  0.662
2002 Razani B, Woodman SE, Lisanti MP. Caveolae: from cell biology to animal physiology. Pharmacological Reviews. 54: 431-67. PMID 12223531 DOI: 10.1124/Pr.54.3.431  0.673
2002 Razani B, Park DS, Miyanaga Y, Ghatpande A, Cohen J, Wang XB, Scherer PE, Evans T, Lisanti MP. Molecular cloning and developmental expression of the caveolin gene family in the amphibian Xenopus laevis. Biochemistry. 41: 7914-24. PMID 12069580 DOI: 10.1021/Bi020043N  0.497
2002 Park DS, Woodman SE, Schubert W, Cohen AW, Frank PG, Chandra M, Shirani J, Razani B, Tang B, Jelicks LA, Factor SM, Weiss LM, Tanowitz HB, Lisanti MP. Caveolin-1/3 double-knockout mice are viable, but lack both muscle and non-muscle caveolae, and develop a severe cardiomyopathic phenotype. The American Journal of Pathology. 160: 2207-17. PMID 12057923 DOI: 10.1016/S0002-9440(10)61168-6  0.757
2002 Sotgia F, Razani B, Bonuccelli G, Schubert W, Battista M, Lee H, Capozza F, Schubert AL, Minetti C, Buckley JT, Lisanti MP. Intracellular retention of glycosylphosphatidyl inositol-linked proteins in caveolin-deficient cells. Molecular and Cellular Biology. 22: 3905-26. PMID 11997523 DOI: 10.1128/Mcb.22.11.3905-3926.2002  0.783
2002 Razani B, Wang XB, Engelman JA, Battista M, Lagaud G, Zhang XL, Kneitz B, Hou H, Christ GJ, Edelmann W, Lisanti MP. Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae. Molecular and Cellular Biology. 22: 2329-44. PMID 11884617 DOI: 10.1128/Mcb.22.7.2329-2344.2002  0.71
2002 Razani B, Combs TP, Wang XB, Frank PG, Park DS, Russell RG, Li M, Tang B, Jelicks LA, Scherer PE, Lisanti MP. Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities. The Journal of Biological Chemistry. 277: 8635-47. PMID 11739396 DOI: 10.1074/Jbc.M110970200  0.715
2001 Razani B, Lisanti MP. Caveolin-deficient mice: insights into caveolar function human disease. The Journal of Clinical Investigation. 108: 1553-61. PMID 11733547 DOI: 10.1172/Jci14611  0.581
2001 Razani B, Lisanti MP. Caveolins and caveolae: molecular and functional relationships. Experimental Cell Research. 271: 36-44. PMID 11697880 DOI: 10.1006/Excr.2001.5372  0.417
2001 Schubert W, Frank PG, Razani B, Park DS, Chow CW, Lisanti MP. Caveolae-deficient endothelial cells show defects in the uptake and transport of albumin in vivo. The Journal of Biological Chemistry. 276: 48619-22. PMID 11689550 DOI: 10.1074/Jbc.C100613200  0.771
2001 Galbiati F, Razani B, Lisanti MP. Caveolae and caveolin-3 in muscular dystrophy. Trends in Molecular Medicine. 7: 435-41. PMID 11597517 DOI: 10.1016/S1471-4914(01)02105-0  0.523
2001 Razani B, Lisanti MP. Two distinct caveolin-1 domains mediate the functional interaction of caveolin-1 with protein kinase A. American Journal of Physiology. Cell Physiology. 281: C1241-50. PMID 11546661 DOI: 10.1152/Ajpcell.2001.281.4.C1241  0.52
2001 Galbiati F, Razani B, Lisanti MP. Emerging themes in lipid rafts and caveolae. Cell. 106: 403-11. PMID 11525727 DOI: 10.1016/S0092-8674(01)00472-X  0.428
2001 Razani B, Schlegel A, Liu J, Lisanti MP. Caveolin-1, a putative tumour suppressor gene. Biochemical Society Transactions. 29: 494-9. PMID 11498016 DOI: 10.1042/Bst0290494  0.665
2001 Razani B, Engelman JA, Wang XB, Schubert W, Zhang XL, Marks CB, Macaluso F, Russell RG, Li M, Pestell RG, Di Vizio D, Hou H, Kneitz B, Lagaud G, Christ GJ, et al. Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities. The Journal of Biological Chemistry. 276: 38121-38. PMID 11457855 DOI: 10.1074/Jbc.M105408200  0.796
2001 Frank PG, Galbiati F, Volonte D, Razani B, Cohen DE, Marcel YL, Lisanti MP. Influence of caveolin-1 on cellular cholesterol efflux mediated by high-density lipoproteins. American Journal of Physiology. Cell Physiology. 280: C1204-14. PMID 11287334 DOI: 10.1152/Ajpcell.2001.280.5.C1204  0.676
2001 Park DS, Razani B, Lasorella A, Schreiber-Agus N, Pestell RG, Iavarone A, Lisanti MP. Evidence that Myc isoforms transcriptionally repress caveolin-1 gene expression via an INR-dependent mechanism. Biochemistry. 40: 3354-62. PMID 11258956 DOI: 10.1021/Bi002787B  0.5
2001 Razani B, Zhang XL, Bitzer M, von Gersdorff G, Böttinger EP, Lisanti MP. Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signaling through an interaction with the TGF-beta type I receptor. The Journal of Biological Chemistry. 276: 6727-38. PMID 11102446 DOI: 10.1074/Jbc.M008340200  0.456
2000 Razani B, Altschuler Y, Zhu L, Pestell RG, Mostov KE, Lisanti MP. Caveolin-1 expression is down-regulated in cells transformed by the human papilloma virus in a p53-dependent manner. Replacement of caveolin-1 expression suppresses HPV-mediated cell transformation. Biochemistry. 39: 13916-24. PMID 11076533 DOI: 10.1021/Bi001489B  0.492
2000 Razani B, Schlegel A, Lisanti MP. Caveolin proteins in signaling, oncogenic transformation and muscular dystrophy. Journal of Cell Science. 113: 2103-9. PMID 10825283  0.621
2000 Zhang W, Razani B, Altschuler Y, Bouzahzah B, Mostov KE, Pestell RG, Lisanti MP. Caveolin-1 inhibits epidermal growth factor-stimulated lamellipod extension and cell migration in metastatic mammary adenocarcinoma cells (MTLn3). Transformation suppressor effects of adenovirus-mediated gene delivery of caveolin-1. The Journal of Biological Chemistry. 275: 20717-25. PMID 10748172 DOI: 10.1074/Jbc.M909895199  0.542
1999 Engelman JA, Zhang XL, Razani B, Pestell RG, Lisanti MP. p42/44 MAP kinase-dependent and -independent signaling pathways regulate caveolin-1 gene expression. Activation of Ras-MAP kinase and protein kinase a signaling cascades transcriptionally down-regulates caveolin-1 promoter activity. The Journal of Biological Chemistry. 274: 32333-41. PMID 10542274 DOI: 10.1074/Jbc.274.45.32333  0.623
1999 Razani B, Rubin CS, Lisanti MP. Regulation of cAMP-mediated signal transduction via interaction of caveolins with the catalytic subunit of protein kinase A. The Journal of Biological Chemistry. 274: 26353-60. PMID 10473592 DOI: 10.1074/Jbc.274.37.26353  0.525
1999 Liu J, Razani B, Tang S, Terman BI, Ware JA, Lisanti MP. Angiogenesis activators and inhibitors differentially regulate caveolin-1 expression and caveolae formation in vascular endothelial cells. Angiogenesis inhibitors block vascular endothelial growth factor-induced down-regulation of caveolin-1. The Journal of Biological Chemistry. 274: 15781-5. PMID 10336480 DOI: 10.1074/Jbc.274.22.15781  0.497
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