| Year |
Citation |
Score |
| 2022 |
Rasheed SAK, Subramanyan LV, Lim WK, Udayappan UK, Wang M, Casey PJ. The emerging roles of Gα12/13 proteins on the hallmarks of cancer in solid tumors. Oncogene. 41: 147-158. PMID 34689178 DOI: 10.1038/s41388-021-02069-w |
0.406 |
|
| 2020 |
Chai TF, Manu KA, Casey PJ, Wang M. Isoprenylcysteine carboxylmethyltransferase is required for the impact of mutant KRAS on TAZ protein level and cancer cell self-renewal. Oncogene. PMID 32561852 DOI: 10.1038/S41388-020-1364-7 |
0.382 |
|
| 2020 |
Lai X, Wang T, Tan TZ, Casey PJ, Hong W, Sudol M, Tergaonkar V, Lee SC, Kumar AP. Abstract A28: DEAD-box RNA helicase DP103 enhances YAP sumoylation for YAP-TEAD dependence and statin sensitivity in triple-negative breast cancer Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Hippo19-A28 |
0.328 |
|
| 2019 |
Lim WK, Chai X, Ghosh S, Ray D, Wang M, Rasheed SAK, Casey PJ. G alpha-13 induces C-X-C motif chemokine ligand 5 expression in prostate cancer cells by transactivating NF-κB. The Journal of Biological Chemistry. PMID 31636124 DOI: 10.1074/Jbc.Ra119.010018 |
0.386 |
|
| 2019 |
Manu KA, Cao PHA, Chai TF, Casey PJ, Wang M. p21cip1/waf1 Coordinate Autophagy, Proliferation and Apoptosis in Response to Metabolic Stress. Cancers. 11. PMID 31382612 DOI: 10.3390/Cancers11081112 |
0.302 |
|
| 2018 |
Manu KA, Chai TF, Teh JT, Zhu W, Casey PJ, Wang M. Abstract 2339: Targeting ICMT in pancreatic cancer Cancer Research. 78: 2339-2339. DOI: 10.1158/1538-7445.Am2018-2339 |
0.321 |
|
| 2017 |
Rasheed SAK, Leong HS, Lakshmanan M, Raju A, Dadlani D, Chong FT, Shannon NB, Rajarethinam R, Skanthakumar T, Tan EY, Hwang JSG, Lim KH, Tan DS, Ceppi P, Wang M, ... ... Casey PJ, et al. GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers. Oncogene. PMID 29255247 DOI: 10.1038/S41388-017-0038-6 |
0.368 |
|
| 2017 |
Do MT, Chai TF, Casey PJ, Wang M. Isoprenylcysteine carboxylmethyltransferase function is essential for RAB4A-mediated integrin β3 recycling, cell migration and cancer metastasis. Oncogene. PMID 28604748 DOI: 10.1038/Onc.2017.183 |
0.364 |
|
| 2017 |
Udayappan UK, Casey PJ. c-Jun Contributes to Transcriptional Control of GNA12 Expression in Prostate Cancer Cells. Molecules (Basel, Switzerland). 22. PMID 28394299 DOI: 10.3390/Molecules22040612 |
0.375 |
|
| 2017 |
Lau HY, Tang J, Casey PJ, Wang M. Isoprenylcysteine carboxylmethyltransferase is critical for malignant transformation and tumor maintenance by all RAS isoforms. Oncogene. PMID 28192404 DOI: 10.1038/Onc.2016.508 |
0.325 |
|
| 2017 |
Manu KA, Chai TF, Teh JT, Zhu WL, Casey PJ, Wang M. Inhibition of Isoprenylcysteine carboxylmethyltransferase induces cell cycle arrest and apoptosis through p21 and p21-regulated BNIP3 induction in pancreatic cancer. Molecular Cancer Therapeutics. PMID 28167504 DOI: 10.1158/1535-7163.Mct-16-0703 |
0.358 |
|
| 2017 |
Ng MY, Wang M, Casey PJ, Gan YH, Hagen T. Activation of MAPK/ERK signaling by Burkholderia pseudomallei cycle inhibiting factor (Cif). Plos One. 12: e0171464. PMID 28166272 DOI: 10.1371/Journal.Pone.0171464 |
0.424 |
|
| 2017 |
Rasheed SAK, Leong HS, Lakshmanan M, Raju A, Dadlani D, Chong F, Rajarethinam R, Skanthakumar T, Tan EY, Hwang JSG, Lim KH, Tan DS, Ceppi P, Wang M, Tergaonkar V, ... Casey PJ, et al. Abstract 3887: GNA13 is a theranostic target that drives drug resistance and cancer stem-like phenotypes in solid tumors Cancer Research. 77: 3887-3887. DOI: 10.1158/1538-7445.Am2017-3887 |
0.34 |
|
| 2016 |
Teo CR, Casey PJ, Rasheed SA. The GNA13-RhoA signaling axis suppresses expression of tumor protective Kallikreins. Cellular Signalling. 28: 1479-1488. PMID 27424208 DOI: 10.1016/J.Cellsig.2016.07.001 |
0.387 |
|
| 2016 |
Wang M, Casey PJ. Protein prenylation: unique fats make their mark on biology. Nature Reviews. Molecular Cell Biology. PMID 26790532 DOI: 10.1038/Nrm.2015.11 |
0.465 |
|
| 2016 |
Leong HS, Rasheed SAK, Lakshmanan M, Raju AK, Tergaonkar V, Tan Ds, Casey P, Iyer NG. Abstract 2505: GNA13 induction of stemness and resistance to chemotherapy in breast and head and neck cancers Cancer Research. 76: 2505-2505. DOI: 10.1158/1538-7445.Am2016-2505 |
0.38 |
|
| 2015 |
Sun WT, Xiang W, Ng BL, Asari K, Bunte RM, Casey PJ, Wang M, Chuah C. Inhibition of isoprenylcysteine carboxylmethyltransferase augments BCR-ABL1 tyrosine kinase inhibition-induced apoptosis in chronic myeloid leukaemia. Experimental Hematology. PMID 26706195 DOI: 10.1016/J.Exphem.2015.12.002 |
0.317 |
|
| 2015 |
Ullah N, Mansha M, Casey PJ. Protein Geranylgeranyltransferase Type 1 as a Target in Cancer. Current Cancer Drug Targets. PMID 26648485 DOI: 10.2174/1568009616666151203224603 |
0.479 |
|
| 2015 |
Rasheed SA, Teo CR, Beillard EJ, Voorhoeve PM, Zhou W, Ghosh S, Casey PJ. MicroRNA-31 controls G protein alpha-13 (GNA13) expression and cell invasion in breast cancer cells. Molecular Cancer. 14: 67. PMID 25889182 DOI: 10.1186/S12943-015-0337-X |
0.328 |
|
| 2015 |
Teh JT, Zhu WL, Ilkayeva OR, Li Y, Gooding J, Casey PJ, Summers SA, Newgard CB, Wang M. Isoprenylcysteine carboxylmethyltransferase regulates mitochondrial respiration and cancer cell metabolism. Oncogene. 34: 3296-304. PMID 25151967 DOI: 10.1038/Onc.2014.260 |
0.394 |
|
| 2014 |
Chia CY, Kumari U, Casey PJ. Breast cancer cell invasion mediated by Gα12 signaling involves expression of interleukins-6 and -8, and matrix metalloproteinase-2. Journal of Molecular Signaling. 9: 6. PMID 24976858 DOI: 10.1186/1750-2187-9-6 |
0.424 |
|
| 2014 |
Lau HY, Ramanujulu PM, Guo D, Yang T, Wirawan M, Casey PJ, Go ML, Wang M. An improved isoprenylcysteine carboxylmethyltransferase inhibitor induces cancer cell death and attenuates tumor growth in vivo. Cancer Biology & Therapy. 15: 1280-91. PMID 24971579 DOI: 10.4161/Cbt.29692 |
0.36 |
|
| 2014 |
Kimple ME, Neuman JC, Linnemann AK, Casey PJ. Inhibitory G proteins and their receptors: emerging therapeutic targets for obesity and diabetes. Experimental & Molecular Medicine. 46: e102. PMID 24946790 DOI: 10.1038/Emm.2014.40 |
0.342 |
|
| 2014 |
Hultman R, Kumari U, Michel N, Casey PJ. Gαz regulates BDNF-induction of axon growth in cortical neurons. Molecular and Cellular Neurosciences. 58: 53-61. PMID 24321455 DOI: 10.1016/J.Mcn.2013.12.004 |
0.753 |
|
| 2013 |
Cushman I, Cushman SM, Potter PM, Casey PJ. Control of RhoA methylation by carboxylesterase I. The Journal of Biological Chemistry. 288: 19177-83. PMID 23658012 DOI: 10.1074/Jbc.M113.467407 |
0.456 |
|
| 2013 |
Zhu Y, Casey PJ, Kumar AP, Pervaiz S. Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases. Cell Death & Disease. 4: e568. PMID 23559002 DOI: 10.1038/Cddis.2013.103 |
0.417 |
|
| 2013 |
Ramanujulu PM, Yang T, Yap SQ, Wong FC, Casey PJ, Wang M, Go ML. Functionalized indoleamines as potent, drug-like inhibitors of isoprenylcysteine carboxyl methyltransferase (Icmt). European Journal of Medicinal Chemistry. 63: 378-86. PMID 23514631 DOI: 10.1016/J.Ejmech.2013.02.007 |
0.385 |
|
| 2013 |
Rasheed SA, Teo CR, Beillard EJ, Voorhoeve PM, Casey PJ. MicroRNA-182 and microRNA-200a control G-protein subunit α-13 (GNA13) expression and cell invasion synergistically in prostate cancer cells. The Journal of Biological Chemistry. 288: 7986-95. PMID 23329838 DOI: 10.1074/Jbc.M112.437749 |
0.361 |
|
| 2013 |
Zhu Y, Casey PJ, Kumar AP, Pervaiz S. Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: Evidence for non-canonical activation of RhoA and Rac1 GTPases Cell Death and Disease. 4. DOI: 10.1038/cddis.2013.103 |
0.303 |
|
| 2012 |
Kimple ME, Moss JB, Brar HK, Rosa TC, Truchan NA, Pasker RL, Newgard CB, Casey PJ. Deletion of GαZ protein protects against diet-induced glucose intolerance via expansion of β-cell mass. The Journal of Biological Chemistry. 287: 20344-55. PMID 22457354 DOI: 10.1074/Jbc.M112.359745 |
0.356 |
|
| 2012 |
Rasheed SAK, Teo CR, Beillard E, Voorhoeve PM, Casey P. Abstract LB-278: MicroRNA control of GNA13 expression and cancer cell invasion Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-278 |
0.361 |
|
| 2011 |
Juneja J, Cushman I, Casey PJ. G12 signaling through c-Jun NH2-terminal kinase promotes breast cancer cell invasion. Plos One. 6: e26085. PMID 22087220 DOI: 10.1371/Journal.Pone.0026085 |
0.416 |
|
| 2011 |
Zhu WL, Hossain MS, Guo DY, Liu S, Tong H, Khakpoor A, Casey PJ, Wang M. A role for Rac3 GTPase in the regulation of autophagy. The Journal of Biological Chemistry. 286: 35291-8. PMID 21852230 DOI: 10.1074/Jbc.M111.280990 |
0.382 |
|
| 2011 |
Dasgupta S, Cushman I, Kpetemey M, Casey PJ, Vishwanatha JK. Prenylated c17orf37 induces filopodia formation to promote cell migration and metastasis. The Journal of Biological Chemistry. 286: 25935-46. PMID 21628459 DOI: 10.1074/Jbc.M111.254599 |
0.453 |
|
| 2011 |
Forrester MT, Hess DT, Thompson JW, Hultman R, Moseley MA, Stamler JS, Casey PJ. Site-specific analysis of protein S-acylation by resin-assisted capture. Journal of Lipid Research. 52: 393-8. PMID 21044946 DOI: 10.1194/Jlr.D011106 |
0.772 |
|
| 2011 |
Cushman I, Casey PJ. RHO methylation matters: a role for isoprenylcysteine carboxylmethyltransferase in cell migration and adhesion. Cell Adhesion & Migration. 5: 11-5. PMID 20798596 DOI: 10.4161/Cam.5.1.13196 |
0.456 |
|
| 2011 |
Hightower KE, Casey PJ. The Enzymology of CAAX Protein Prenylation Enzymes. 30: 1-11. DOI: 10.1016/B978-0-12-415922-8.00001-X |
0.44 |
|
| 2010 |
Go ML, Leow JL, Gorla SK, Schüller AP, Wang M, Casey PJ. Amino derivatives of indole as potent inhibitors of isoprenylcysteine carboxyl methyltransferase Journal of Medicinal Chemistry. 53: 6838-6850. PMID 20809634 DOI: 10.1021/Jm1002843 |
0.36 |
|
| 2010 |
Wang M, Hossain MS, Tan W, Coolman B, Zhou J, Liu S, Casey PJ. Inhibition of isoprenylcysteine carboxylmethyltransferase induces autophagic-dependent apoptosis and impairs tumor growth Oncogene. 29: 4959-4970. PMID 20622895 DOI: 10.1038/Onc.2010.247 |
0.308 |
|
| 2010 |
Mizrahi A, Berdichevsky Y, Casey PJ, Pick E. A prenylated p47phox-p67phox-Rac1 chimera is a Quintessential NADPH oxidase activator: membrane association and functional capacity. The Journal of Biological Chemistry. 285: 25485-99. PMID 20529851 DOI: 10.1074/Jbc.M110.113779 |
0.316 |
|
| 2010 |
Kelly P, Bailey CL, Fueger PT, Newgard CB, Casey PJ, Kimple ME. Rap1 promotes multiple pancreatic islet cell functions and signals through mammalian target of rapamycin complex 1 to enhance proliferation. The Journal of Biological Chemistry. 285: 15777-85. PMID 20339002 DOI: 10.1074/Jbc.M109.069112 |
0.672 |
|
| 2010 |
Doughty-Shenton D, Joseph JD, Zhang J, Pagliarini DJ, Kim Y, Lu D, Dixon JE, Casey PJ. Pharmacological targeting of the mitochondrial phosphatase PTPMT1. The Journal of Pharmacology and Experimental Therapeutics. 333: 584-92. PMID 20167843 DOI: 10.1124/Jpet.109.163329 |
0.392 |
|
| 2010 |
Kimple ME, Hultman RC, Casey PJ. Signaling through Gz Handbook of Cell Signaling, 2/E. 2: 1649-1653. DOI: 10.1016/B978-0-12-374145-5.00202-3 |
0.788 |
|
| 2009 |
Cushman I, Casey PJ. Role of isoprenylcysteine carboxylmethyltransferase-catalyzed methylation in Rho function and migration. The Journal of Biological Chemistry. 284: 27964-73. PMID 19651782 DOI: 10.1074/Jbc.M109.025296 |
0.451 |
|
| 2009 |
Peterson YK, Wang XS, Casey PJ, Tropsha A. Discovery of geranylgeranyltransferase-I inhibitors with novel scaffolds by the means of quantitative structure-activity relationship modeling, virtual screening, and experimental validation. Journal of Medicinal Chemistry. 52: 4210-20. PMID 19537691 DOI: 10.1021/Jm8013772 |
0.71 |
|
| 2009 |
Rossol-Allison J, Stemmle LN, Swenson-Fields KI, Kelly P, Fields PE, McCall SJ, Casey PJ, Fields TA. Rho GTPase activity modulates Wnt3a/beta-catenin signaling. Cellular Signalling. 21: 1559-68. PMID 19482078 DOI: 10.1016/J.Cellsig.2009.05.010 |
0.766 |
|
| 2009 |
Bailey CL, Kelly P, Casey PJ. Activation of Rap1 promotes prostate cancer metastasis. Cancer Research. 69: 4962-8. PMID 19470770 DOI: 10.1158/0008-5472.Can-08-4269 |
0.64 |
|
| 2009 |
Juneja J, Casey PJ. Role of G12 proteins in oncogenesis and metastasis. British Journal of Pharmacology. 158: 32-40. PMID 19422395 DOI: 10.1111/J.1476-5381.2009.00180.X |
0.467 |
|
| 2009 |
Wright LP, Court H, Mor A, Ahearn IM, Casey PJ, Philips MR. Topology of mammalian isoprenylcysteine carboxyl methyltransferase determined in live cells with a fluorescent probe. Molecular and Cellular Biology. 29: 1826-33. PMID 19158273 DOI: 10.1128/Mcb.01719-08 |
0.37 |
|
| 2009 |
Wang M, Khoo YM, Zhou J, Casey P, Lee HS. A high-performance liquid chromatography method for the quantification of cysmethynil, an inhibitor of isoprenylcysteine carboxylmethyl transferase, in mouse plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 877: 553-7. PMID 19157999 DOI: 10.1016/J.Jchromb.2008.12.067 |
0.301 |
|
| 2009 |
Tian Sun W, Ng BL, Yang LY, Wang M, Hwang W, Melo JV, Druker BJ, Casey PJ, Chuah C. Targeting Isoprenylcysteine Carboxyl Methyltransferase to Overcome Resistance and Improve Responses in Chronic Myeloid Leukemia. Blood. 114: 3273-3273. DOI: 10.1182/Blood.V114.22.3273.3273 |
0.342 |
|
| 2008 |
Katadae M, Hagiwara K, Wada A, Ito M, Umeda M, Casey PJ, Fukada Y. Interacting targets of the farnesyl of transducin gamma-subunit. Biochemistry. 47: 8424-33. PMID 18636747 DOI: 10.1021/Bi800359H |
0.413 |
|
| 2008 |
Wang M, Tan W, Zhou J, Leow J, Go M, How SL, Casey PJ. A small molecule inhibitor of isoprenylcysteine carboxymethyltransferase induces autophagic cell death in PC3 prostate cancer cells Journal of Biological Chemistry. 283: 18678-18684. PMID 18434300 DOI: 10.1074/Jbc.M801855200 |
0.398 |
|
| 2008 |
Rao PV, Peterson YK, Inoue T, Casey PJ. Effects of pharmacologic inhibition of protein geranylgeranyltransferase type I on aqueous humor outflow through the trabecular meshwork. Investigative Ophthalmology & Visual Science. 49: 2464-71. PMID 18316706 DOI: 10.1167/Iovs.07-1639 |
0.713 |
|
| 2008 |
Kimple ME, Joseph JW, Bailey CL, Fueger PT, Hendry IA, Newgard CB, Casey PJ. Galphaz negatively regulates insulin secretion and glucose clearance. The Journal of Biological Chemistry. 283: 4560-7. PMID 18096703 DOI: 10.1074/Jbc.M706481200 |
0.562 |
|
| 2008 |
Bahmanyar S, Kaplan DD, Deluca JG, Giddings TH, O'Toole ET, Winey M, Salmon ED, Casey PJ, Nelson WJ, Barth AI. beta-Catenin is a Nek2 substrate involved in centrosome separation. Genes & Development. 22: 91-105. PMID 18086858 DOI: 10.1101/Gad.1596308 |
0.309 |
|
| 2007 |
Kelly P, Casey PJ, Meigs TE. Biologic functions of the G12 subfamily of heterotrimeric g proteins: growth, migration, and metastasis. Biochemistry. 46: 6677-87. PMID 17503779 DOI: 10.1021/Bi700235F |
0.479 |
|
| 2007 |
Sjogren AK, Andersson KM, Liu M, Cutts BA, Karlsson C, Wahlstrom AM, Dalin M, Weinbaum C, Casey PJ, Tarkowski A, Swolin B, Young SG, Bergo MO. GGTase-I deficiency reduces tumor formation and improves survival in mice with K-RAS-induced lung cancer. The Journal of Clinical Investigation. 117: 1294-304. PMID 17476360 DOI: 10.1172/Jci30868 |
0.365 |
|
| 2007 |
Baron RA, Peterson YK, Otto JC, Rudolph J, Casey PJ. Time-dependent inhibition of isoprenylcysteine carboxyl methyltransferase by indole-based small molecules. Biochemistry. 46: 554-60. PMID 17209565 DOI: 10.1021/Bi060344N |
0.664 |
|
| 2006 |
Terry KL, Casey PJ, Beese LS. Conversion of protein farnesyltransferase to a geranylgeranyltransferase. Biochemistry. 45: 9746-55. PMID 16893176 DOI: 10.1021/Bi060295E |
0.488 |
|
| 2006 |
Stemmle LN, Fields TA, Casey PJ. The regulator of G protein signaling domain of axin selectively interacts with Galpha12 but not Galpha13. Molecular Pharmacology. 70: 1461-8. PMID 16868183 DOI: 10.1124/Mol.106.023705 |
0.814 |
|
| 2006 |
Kelly P, Stemmle LN, Madden JF, Fields TA, Daaka Y, Casey PJ. A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion. The Journal of Biological Chemistry. 281: 26483-90. PMID 16787920 DOI: 10.1074/Jbc.M604376200 |
0.791 |
|
| 2006 |
Svensson AW, Casey PJ, Young SG, Bergo MO. Genetic and pharmacologic analyses of the role of Icmt in Ras membrane association and function. Methods in Enzymology. 407: 144-59. PMID 16757321 DOI: 10.1016/S0076-6879(05)07013-8 |
0.424 |
|
| 2006 |
Kelly P, Moeller BJ, Juneja J, Booden MA, Der CJ, Daaka Y, Dewhirst MW, Fields TA, Casey PJ. The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis. Proceedings of the National Academy of Sciences of the United States of America. 103: 8173-8. PMID 16705036 DOI: 10.1073/Pnas.0510254103 |
0.355 |
|
| 2006 |
Peterson YK, Kelly P, Weinbaum CA, Casey PJ. A novel protein geranylgeranyltransferase-I inhibitor with high potency, selectivity, and cellular activity. The Journal of Biological Chemistry. 281: 12445-50. PMID 16517596 DOI: 10.1074/Jbc.M600168200 |
0.725 |
|
| 2006 |
Wang M, Casey PJ. Isoprenylcysteine carboxylmethyltransferase as a target for development of novel cancer therapeutics Drugs of the Future. 31: 437-445. DOI: 10.1358/Dof.2006.031.05.994707 |
0.482 |
|
| 2005 |
Kimple ME, Nixon AB, Kelly P, Bailey CL, Young KH, Fields TA, Casey PJ. A role for G(z) in pancreatic islet beta-cell biology. The Journal of Biological Chemistry. 280: 31708-13. PMID 16157560 DOI: 10.1074/Jbc.M506700200 |
0.627 |
|
| 2005 |
Pagliarini DJ, Wiley SE, Kimple ME, Dixon JR, Kelly P, Worby CA, Casey PJ, Dixon JE. Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic beta cells. Molecular Cell. 19: 197-207. PMID 16039589 DOI: 10.1016/J.Molcel.2005.06.008 |
0.342 |
|
| 2005 |
Winter-Vann AM, Casey PJ. Post-prenylation-processing enzymes as new targets in oncogenesis. Nature Reviews. Cancer. 5: 405-12. PMID 15864282 DOI: 10.1038/Nrc1612 |
0.789 |
|
| 2005 |
Mijimolle N, Velasco J, Dubus P, Guerra C, Weinbaum CA, Casey PJ, Campuzano V, Barbacid M. Protein farnesyltransferase in embryogenesis, adult homeostasis, and tumor development. Cancer Cell. 7: 313-24. PMID 15837621 DOI: 10.1016/J.Ccr.2005.03.004 |
0.373 |
|
| 2005 |
Winter-Vann AM, Baron RA, Wong W, dela Cruz J, York JD, Gooden DM, Bergo MO, Young SG, Toone EJ, Casey PJ. A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 4336-41. PMID 15784746 DOI: 10.1073/Pnas.0408107102 |
0.805 |
|
| 2005 |
Meigs TE, Juneja J, DeMarco CT, Stemmle LN, Kaplan DD, Casey PJ. Selective uncoupling of G alpha 12 from Rho-mediated signaling. The Journal of Biological Chemistry. 280: 18049-55. PMID 15746095 DOI: 10.1074/Jbc.M500445200 |
0.82 |
|
| 2005 |
Clancy SM, Fowler CE, Finley M, Suen KF, Arrabit C, Berton F, Kosaza T, Casey PJ, Slesinger PA. Pertussis-toxin-sensitive Galpha subunits selectively bind to C-terminal domain of neuronal GIRK channels: evidence for a heterotrimeric G-protein-channel complex. Molecular and Cellular Neurosciences. 28: 375-89. PMID 15691717 DOI: 10.1016/J.Mcn.2004.10.009 |
0.377 |
|
| 2005 |
Kasbohm EA, Guo R, Yowell CW, Bagchi G, Kelly P, Arora P, Casey PJ, Daaka Y. Androgen receptor activation by G(s) signaling in prostate cancer cells. The Journal of Biological Chemistry. 280: 11583-9. PMID 15653681 DOI: 10.1074/Jbc.M414423200 |
0.361 |
|
| 2004 |
Baron RA, Casey PJ. Analysis of the kinetic mechanism of recombinant human isoprenylcysteine carboxylmethyltransferase (Icmt). Bmc Biochemistry. 5: 19. PMID 15625008 DOI: 10.1186/1471-2091-5-19 |
0.402 |
|
| 2004 |
Nixon AB, Casey PJ. Analysis of the regulation of microtubule dynamics by interaction of RGSZ1 (RGS20) with the neuronal stathmin, SCG10. Methods in Enzymology. 390: 53-64. PMID 15488170 DOI: 10.1016/S0076-6879(04)90004-3 |
0.484 |
|
| 2004 |
Reid TS, Terry KL, Casey PJ, Beese LS. Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity. Journal of Molecular Biology. 343: 417-33. PMID 15451670 DOI: 10.1016/J.Jmb.2004.08.056 |
0.4 |
|
| 2004 |
Embry AC, Glick JL, Linder ME, Casey PJ. Reciprocal signaling between the transcriptional co-factor Eya2 and specific members of the Galphai family. Molecular Pharmacology. 66: 1325-31. PMID 15308761 DOI: 10.1124/Mol.104.004093 |
0.759 |
|
| 2004 |
Bergo MO, Gavino BJ, Hong C, Beigneux AP, McMahon M, Casey PJ, Young SG. Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf. The Journal of Clinical Investigation. 113: 539-50. PMID 14966563 DOI: 10.1172/Jci18829 |
0.344 |
|
| 2004 |
Kaplan DD, Meigs TE, Kelly P, Casey PJ. Identification of a role for beta-catenin in the establishment of a bipolar mitotic spindle. The Journal of Biological Chemistry. 279: 10829-32. PMID 14744872 DOI: 10.1074/Jbc.C400035200 |
0.317 |
|
| 2004 |
Hagiwara K, Wada A, Katadae M, Ito M, Ohya Y, Casey PJ, Fukada Y. Analysis of the molecular interaction of the farnesyl moiety of transducin through the use of a photoreactive farnesyl analogue. Biochemistry. 43: 300-9. PMID 14717583 DOI: 10.1021/Bi0351514 |
0.397 |
|
| 2004 |
Bergo MO, Lieu HD, Gavino BJ, Ambroziak P, Otto JC, Casey PJ, Walker QM, Young SG. On the physiological importance of endoproteolysis of CAAX proteins: heart-specific RCE1 knockout mice develop a lethal cardiomyopathy. The Journal of Biological Chemistry. 279: 4729-36. PMID 14625273 DOI: 10.1074/Jbc.M310081200 |
0.343 |
|
| 2004 |
Casey P. Protein farnesyltransferase, beta subunit Afcs-Nature Molecule Pages. DOI: 10.1038/Mp.A002456.01 |
0.352 |
|
| 2003 |
Taylor JS, Reid TS, Terry KL, Casey PJ, Beese LS. Structure of mammalian protein geranylgeranyltransferase type-I. The Embo Journal. 22: 5963-74. PMID 14609943 DOI: 10.1093/Emboj/Cdg571 |
0.389 |
|
| 2003 |
Pickett JS, Bowers KE, Hartman HL, Fu HW, Embry AC, Casey PJ, Fierke CA. Kinetic studies of protein farnesyltransferase mutants establish active substrate conformation. Biochemistry. 42: 9741-8. PMID 12911316 DOI: 10.1021/Bi0346852 |
0.649 |
|
| 2003 |
Fiordalisi JJ, Johnson RL, Weinbaum CA, Sakabe K, Chen Z, Casey PJ, Cox AD. High affinity for farnesyltransferase and alternative prenylation contribute individually to K-Ras4B resistance to farnesyltransferase inhibitors. The Journal of Biological Chemistry. 278: 41718-27. PMID 12882980 DOI: 10.1074/Jbc.M305733200 |
0.558 |
|
| 2003 |
Winter-Vann AM, Kamen BA, Bergo MO, Young SG, Melnyk S, James SJ, Casey PJ. Targeting Ras signaling through inhibition of carboxyl methylation: an unexpected property of methotrexate. Proceedings of the National Academy of Sciences of the United States of America. 100: 6529-34. PMID 12750467 DOI: 10.1073/Pnas.1135239100 |
0.794 |
|
| 2003 |
Meng J, Casey PJ. Signaling Through G<inf>z</inf> Handbook of Cell Signaling. 2: 601-604. DOI: 10.1016/B978-012124546-7/50580-5 |
0.545 |
|
| 2002 |
Gilman AG, Simon MI, Bourne HR, Harris BA, Long R, Ross EM, Stull JT, Taussig R, Bourne HR, Arkin AP, Cobb MH, Cyster JG, Devreotes PN, Ferrell JE, Fruman D, ... ... Casey PJ, et al. Overview of the Alliance for Cellular Signaling. Nature. 420: 703-6. PMID 12478301 DOI: 10.1038/Nature01304 |
0.741 |
|
| 2002 |
Long SB, Casey PJ, Beese LS. Reaction path of protein farnesyltransferase at atomic resolution. Nature. 419: 645-50. PMID 12374986 DOI: 10.1038/Nature00986 |
0.416 |
|
| 2002 |
Meng J, Casey PJ. Activation of Gz attenuates Rap1-mediated differentiation of PC12 cells. The Journal of Biological Chemistry. 277: 43417-24. PMID 12198116 DOI: 10.1074/Jbc.M204074200 |
0.634 |
|
| 2002 |
Meigs TE, Fedor-Chaiken M, Kaplan DD, Brackenbury R, Casey PJ. Galpha12 and Galpha13 negatively regulate the adhesive functions of cadherin. The Journal of Biological Chemistry. 277: 24594-600. PMID 11976333 DOI: 10.1074/jbc.M201984200 |
0.37 |
|
| 2002 |
Nixon AB, Grenningloh G, Casey PJ. The interaction of RGSZ1 with SCG10 attenuates the ability of SCG10 to promote microtubule disassembly. The Journal of Biological Chemistry. 277: 18127-33. PMID 11882662 DOI: 10.1074/Jbc.M201065200 |
0.506 |
|
| 2002 |
Bergo MO, Ambroziak P, Gregory C, George A, Otto JC, Kim E, Nagase H, Casey PJ, Balmain A, Young SG. Absence of the CAAX endoprotease Rce1: effects on cell growth and transformation. Molecular and Cellular Biology. 22: 171-81. PMID 11739732 DOI: 10.1128/Mcb.22.1.171-181.2002 |
0.397 |
|
| 2002 |
Hurwitz HI, Casey PJ. Prenylation of CaaX-type proteins: Basic principles through clinical applications Current Topics in Membranes. 52: 531-550. DOI: 10.1016/S1063-5823(02)52021-4 |
0.456 |
|
| 2001 |
Hightower KE, De S, Weinbaum C, Spence RA, Casey PJ. Lysine 164 α of protein farnesyltransferase is important for both CaaX substrate binding and catalysis Biochemical Journal. 360: 625-631. PMID 11736652 DOI: 10.1042/Bj3600625 |
0.35 |
|
| 2001 |
Kaplan DD, Meigs TE, Casey PJ. Distinct Regions of the Cadherin Cytoplasmic Domain Are Essential for Functional Interaction with Gα12 and β-Catenin Journal of Biological Chemistry. 276: 44037-44043. PMID 11546809 DOI: 10.1074/Jbc.M106121200 |
0.351 |
|
| 2001 |
Burgon PG, Lee WL, Nixon AB, Peralta EG, Casey PJ. Phosphorylation and Nuclear Translocation of a Regulator of G Protein Signaling (RGS10) Journal of Biological Chemistry. 276: 32828-32834. PMID 11443111 DOI: 10.1074/Jbc.M100960200 |
0.489 |
|
| 2001 |
Schlitzer M, Winter-Vann A, Casey PJ. Non-peptidic, non-prenylic inhibitors of the prenyl protein-specific protease Rce1 Bioorganic and Medicinal Chemistry Letters. 11: 425-427. PMID 11212127 DOI: 10.1016/S0960-894X(00)00685-5 |
0.781 |
|
| 2001 |
Hightower KE, Casey PJ, Fierke CA. Farnesylation of nonpeptidic thiol compounds by protein farnesyltransferase. Biochemistry. 40: 1002-10. PMID 11170422 DOI: 10.1021/Bi002237D |
0.407 |
|
| 2001 |
Meigs TE, Fields TA, McKee DD, Casey PJ. Interaction of Gα12 and Gα13 with the cytoplasmic domain of cadherin provides a mechanism for β-catenin release Proceedings of the National Academy of Sciences of the United States of America. 98: 519-524. PMID 11136230 DOI: 10.1073/Pnas.98.2.519 |
0.456 |
|
| 2001 |
Bergo MO, Leung GK, Ambroziak P, Otto JC, Casey PJ, Gomes AQ, Seabra MC, Young SG. Isoprenylcysteine carboxyl methyltransferase deficiency in mice. The Journal of Biological Chemistry. 276: 5841-5. PMID 11121396 DOI: 10.1074/Jbc.C000831200 |
0.393 |
|
| 2001 |
Tschantz WR, Digits JA, Pyun HJ, Coates RM, Casey PJ. Lysosomal prenylcysteine lyase is a FAD-dependent thioether oxidase. The Journal of Biological Chemistry. 276: 2321-4. PMID 11078725 DOI: 10.1074/Jbc.C000616200 |
0.353 |
|
| 2001 |
Spence RA, Casey PJ. 1 Mechanism of catalysis by protein farnesyltransferase Enzymes. 21: 1-18. DOI: 10.1016/S1874-6047(01)80014-7 |
0.38 |
|
| 2000 |
Spence RA, Hightower KE, Terry KL, Beese LS, Fierke CA, Casey PJ. Conversion of Tyr361 beta to Leu in mammalian protein farnesyltransferase impairs product release but not substrate recognition. Biochemistry. 39: 13651-9. PMID 11076503 DOI: 10.1021/Bi001084R |
0.409 |
|
| 2000 |
Chen Z, Otto JC, Bergo MO, Young SG, Casey PJ. The C-terminal polylysine region and methylation of K-Ras are critical for the interaction between K-Ras and microtubules. The Journal of Biological Chemistry. 275: 41251-7. PMID 11007785 DOI: 10.1074/Jbc.M006687200 |
0.563 |
|
| 2000 |
Bergo MO, Leung GK, Ambroziak P, Otto JC, Casey PJ, Young SG. Targeted inactivation of the isoprenyleysteine carboxyl methyltransferase gene causes mislocalization of K-Ras in mammalian cells Journal of Biological Chemistry. 275: 17605-17610. PMID 10747846 DOI: 10.1074/Jbc.C000079200 |
0.354 |
|
| 2000 |
Long SB, Casey PJ, Beese LS. The basis for K-Ras4B binding specificity to protein farnesyltransferase revealed by 2 A resolution ternary complex structures. Structure (London, England : 1993). 8: 209-22. PMID 10673434 DOI: 10.1016/S0969-2126(00)00096-4 |
0.365 |
|
| 1999 |
Meng J, Glick JL, Polakis P, Casey PJ. Functional interaction between Galpha(z) and Rap1GAP suggests a novel form of cellular cross-talk. The Journal of Biological Chemistry. 274: 36663-9. PMID 10593970 DOI: 10.1074/Jbc.274.51.36663 |
0.686 |
|
| 1999 |
Tschantz WR, Zhang L, Casey PJ. Cloning, expression, and cellular localization of a human prenylcysteine lyase Journal of Biological Chemistry. 274: 35802-35808. PMID 10585463 DOI: 10.1074/Jbc.274.50.35802 |
0.387 |
|
| 1999 |
Fu HW, Casey PJ. Enzymology and biology of CaaX protein prenylation Recent Progress in Hormone Research. 54: 315-343. PMID 10548882 |
0.374 |
|
| 1999 |
Kim E, Ambroziak P, Otto JC, Taylor B, Ashby M, Shannon K, Casey PJ, Young SG. Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells. The Journal of Biological Chemistry. 274: 8383-90. PMID 10085069 DOI: 10.1074/Jbc.274.13.8383 |
0.368 |
|
| 1999 |
Otto JC, Kim E, Young SG, Casey PJ. Cloning and characterization of a mammalian prenyl protein-specific protease Journal of Biological Chemistry. 274: 8379-8382. PMID 10085068 DOI: 10.1074/Jbc.274.13.8379 |
0.467 |
|
| 1998 |
Hightower KE, Huang CC, Casey PJ, Fierke CA. H-Ras peptide and protein substrates bind protein farnesyltransferase as an ionized thiolate. Biochemistry. 37: 15555-62. PMID 9799520 DOI: 10.1021/Bi981525V |
0.332 |
|
| 1998 |
Glick JL, Meigs TE, Miron A, Casey PJ. RGSZ1, a Gz-selective regulator of G protein signaling whose action is sensitive to the phosphorylation state of Gzalpha. The Journal of Biological Chemistry. 273: 26008-13. PMID 9748279 DOI: 10.1074/Jbc.273.40.26008 |
0.521 |
|
| 1998 |
Long SB, Casey PJ, Beese LS. Cocrystal structure of protein farnesyltransferase complexed with a farnesyl diphosphate substrate. Biochemistry. 37: 9612-8. PMID 9657673 DOI: 10.1021/Bi980708E |
0.396 |
|
| 1998 |
Fu HW, Beese LS, Casey PJ. Kinetic analysis of zinc ligand mutants of mammalian protein farnesyltransferase. Biochemistry. 37: 4465-72. PMID 9521766 DOI: 10.1021/Bi972511C |
0.348 |
|
| 1997 |
Hurwitz LM, Casey PJ. Can prenylcysteines be exploited as ligands for mammalian multidrug-resistance transporters? Chemistry and Biology. 4: 711-715. PMID 9375248 DOI: 10.1016/S1074-5521(97)90308-2 |
0.334 |
|
| 1997 |
Thissen JA, Gross JM, Subramanian K, Meyer T, Casey PJ. Prenylation-dependent association of Ki-Ras with microtubules. Evidence for a role in subcellular trafficking. The Journal of Biological Chemistry. 272: 30362-70. PMID 9374526 DOI: 10.1074/Jbc.272.48.30362 |
0.42 |
|
| 1997 |
Zhang L, Tschantz WR, Casey PJ. Isolation and characterization of a prenylcysteine lyase from bovine brain Journal of Biological Chemistry. 272: 23354-23359. PMID 9287348 DOI: 10.1074/Jbc.272.37.23354 |
0.4 |
|
| 1997 |
Lebowitz PF, Casey PJ, Prendergast GC, Thissen JA. Farnesyltransferase inhibitors alter the prenylation and growth-stimulating function of RhoB. The Journal of Biological Chemistry. 272: 15591-4. PMID 9188444 DOI: 10.1074/Jbc.272.25.15591 |
0.395 |
|
| 1997 |
Park HW, Boduluri SR, Moomaw JF, Casey PJ, Beese LS. Crystal structure of protein farnesyltransferase at 2.25 angstrom resolution. Science (New York, N.Y.). 275: 1800-4. PMID 9065406 DOI: 10.1126/Science.275.5307.1800 |
0.422 |
|
| 1997 |
Fields TA, Casey PJ. Signalling functions and biochemical properties of pertussis toxin-resistant G-proteins Biochemical Journal. 321: 561-571. PMID 9032437 DOI: 10.1042/Bj3210561 |
0.464 |
|
| 1997 |
Tschantz WR, Furfine ES, Casey PJ. Substrate binding is required for release of product from mammalian protein farnesyltransferase Faseb Journal. 11. DOI: 10.1074/Jbc.272.15.9989 |
0.347 |
|
| 1997 |
Otto JC, Casey PJ. Analysis of the C-terminal proteolysis of prenylated proteins Faseb Journal. 11. |
0.335 |
|
| 1996 |
Zhang FL, Casey PJ. Influence of metal ions on substrate binding and catalytic activity of mammalian protein geranylgeranyltransferase type-I Biochemical Journal. 320: 925-932. PMID 9003382 DOI: 10.1042/Bj3200925 |
0.349 |
|
| 1996 |
Higgins JB, Casey PJ. The role of prenylation in G-protein assembly and function Cellular Signalling. 8: 433-437. PMID 8958445 DOI: 10.1016/S0898-6568(96)00071-X |
0.485 |
|
| 1996 |
Thissen JA, Casey PJ. Kinetics of protein farnesyltransferase: Sigmoidal vs hyperbolic behavior as a function of assay conditions Analytical Biochemistry. 243: 80-85. PMID 8954528 DOI: 10.1006/Abio.1996.0484 |
0.367 |
|
| 1996 |
Fu HW, Moomaw JF, Moomaw CR, Casey PJ. Identification of a cysteine residue essential for activity of protein farnesyltransferase: Cys 299 is exposed only upon removal of zinc from the enzyme Journal of Biological Chemistry. 271: 28541-28548. PMID 8910483 DOI: 10.1074/Jbc.271.45.28541 |
0.38 |
|
| 1996 |
Zhang FL, Casey PJ. Protein prenylation: Molecular mechanisms and functional consequences Annual Review of Biochemistry. 65: 241-269. PMID 8811180 DOI: 10.1146/Annurev.Bi.65.070196.001325 |
0.479 |
|
| 1996 |
Hunt TW, Fields TA, Casey PJ, Peralta EG. RGS10 is a selective activator of Gα(i) GTPase activity Nature. 383: 175-177. PMID 8774883 DOI: 10.1038/383175A0 |
0.509 |
|
| 1996 |
Glick J, Santoyo G, Casey PJ. Arachidonate and related unsaturated fatty acids selectively inactivate the guanine nucleotide-binding regulatory protein, Gz. The Journal of Biological Chemistry. 271: 2949-54. PMID 8621685 DOI: 10.1074/Jbc.271.6.2949 |
0.427 |
|
| 1996 |
Casey PJ, Seabra MC. Protein prenyltransferases Journal of Biological Chemistry. 271: 5289-5292. PMID 8621375 DOI: 10.1074/jbc.271.10.5289 |
0.302 |
|
| 1996 |
Otto JC, Casey PJ. The hepatitis delta virus large antigen is farnesylated both in vitro and in animal cells Journal of Biological Chemistry. 271: 4569-4572. DOI: 10.1074/Jbc.271.9.4569 |
0.425 |
|
| 1996 |
Higgins JB, Casey PJ. [8] Assays for G protein βγ subunit activity Methods in Neurosciences. 29: 90-100. DOI: 10.1016/S1043-9471(96)80044-9 |
0.372 |
|
| 1995 |
Casey PJ. Mechanisms of protein prenylation and role in G protein function Biochemical Society Transactions. 23: 161-166. PMID 7758720 DOI: 10.1042/Bst0230161 |
0.457 |
|
| 1995 |
Furfine ES, Leban JJ, Landavazo A, Moomaw JF, Casey PJ. Protein farnesyltransferase: kinetics of farnesyl pyrophosphate binding and product release. Biochemistry. 34: 6857-62. PMID 7756316 DOI: 10.1021/Bi00020A032 |
0.33 |
|
| 1995 |
Casey PJ. Protein lipidation in cell signaling Science. 268: 221-225. PMID 7716512 DOI: 10.1126/Science.7716512 |
0.402 |
|
| 1995 |
Thissen JA, Barrett MG, Casey PJ. Prenylated peptides in identification of specific binding proteins Methods in Enzymology. 250: 158-168. PMID 7651148 DOI: 10.1016/0076-6879(95)50070-7 |
0.343 |
|
| 1995 |
Moomaw JF, Zhang FL, Casey PJ. Isolation of protein prenyltransferases from bovine brain and baculovirus expression system Methods in Enzymology. 250: 12-21. PMID 7651144 DOI: 10.1016/0076-6879(95)50058-8 |
0.428 |
|
| 1995 |
Huang CL, Slesinger PA, Casey PJ, Jan YN, Jan LY. Evidence that direct binding of G beta gamma to the GIRK1 G protein-gated inwardly rectifying K+ channel is important for channel activation. Neuron. 15: 1133-43. PMID 7576656 DOI: 10.1016/0896-6273(95)90101-9 |
0.388 |
|
| 1995 |
Fields TA, Casey PJ. Phosphorylation of GΖα by protein kinase C blocks interaction with the βγ complex Journal of Biological Chemistry. 270: 23119-23125. PMID 7559455 DOI: 10.1074/Jbc.270.39.23119 |
0.433 |
|
| 1995 |
Zhang L, Sachs CW, Fu HW, Fine RL, Casey PJ. Characterization of prenylcysteines that interact with P-glycoprotein and inhibit drug transport in tumor cells. The Journal of Biological Chemistry. 270: 22859-65. PMID 7559420 DOI: 10.1074/Jbc.270.39.22859 |
0.339 |
|
| 1994 |
Fields TA, Linder ME, Casey PJ. Subtype-specific binding of azidoanilido-GTP by purified G protein α subunits Biochemistry. 33: 6877-6883. PMID 8204622 DOI: 10.1021/Bi00188A017 |
0.611 |
|
| 1994 |
Casey PJ, Moomaw JP, Zhang FL, Higgins JB, Thissen JA. Prenylation and G protein signaling Recent Progress in Hormone Research. 49: 215-238. PMID 8146425 DOI: 10.1016/B978-0-12-571149-4.50015-5 |
0.51 |
|
| 1994 |
Casey PJ. Lipid modifications of G proteins Current Opinion in Cell Biology. 6: 219-225. PMID 8024813 DOI: 10.1016/0955-0674(94)90139-2 |
0.475 |
|
| 1994 |
Moomaw JF, Casey PJ. Expression of Mammalian Protein Farnesyltransferase in a Baculovirus System Animal Cell Technologyproducts of Today, Prospects For Tomorrow. 617-618. DOI: 10.1016/B978-0-7506-1845-8.50140-X |
0.386 |
|
| 1993 |
Chen WJ, Moomaw JF, Overton L, Kost TA, Casey PJ. High level expression of mammalian protein farnesyltransferase in a baculovirus system: The purified protein contains zinc Journal of Biological Chemistry. 268: 9675-9680. PMID 8486655 |
0.339 |
|
| 1992 |
Colombo MI, Mayorga LS, Casey PJ, Stahl PD. Evidence of a role for heterotrimeric GTP-binding proteins in endosome fusion Science. 255: 1695-1697. PMID 1348148 DOI: 10.1126/Science.1348148 |
0.49 |
|
| 1992 |
Pitcher JA, Inglese J, Higgins JB, Arriza JL, Casey PJ, Kim C, Benovic JL, Kwatra MM, Caron MG, Lefkowitz RJ. Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors. Science (New York, N.Y.). 257: 1264-7. PMID 1325672 DOI: 10.1126/Science.1325672 |
0.318 |
|
| 1991 |
Seabra MC, Reiss Y, Casey PJ, Brown MS, Goldstein JL. Protein farnesyltransferase and geranylgeranyltransferase share a common α subunit Cell. 65: 429-434. PMID 2018975 DOI: 10.1016/0092-8674(91)90460-G |
0.36 |
|
| 1991 |
Casey PJ, Thissen JA, Moomaw JF. Enzymatic modification of proteins with a geranylgeranyl isoprenoid Proceedings of the National Academy of Sciences of the United States of America. 88: 8631-8635. PMID 1924324 DOI: 10.1073/Pnas.88.19.8631 |
0.458 |
|
| 1991 |
Casey PJ, Pang IH, Gilman AG. Assay of G-protein beta gamma-subunit complex by catalytic support of ADP-ribosylation of Go alpha. Methods in Enzymology. 195: 315-21. PMID 1903494 DOI: 10.1016/0076-6879(91)95176-K |
0.593 |
|
| 1991 |
Buss JE, Quilliam LA, Kato K, Casey PJ, Solski PA, Wong G, Clark R, McCormick F, Bokoch GM, Der CJ. The COOH-terminal domain of the Rap1A (Krev-1) protein is isoprenylated and supports transformation by an H-Ras:Rap1A chimeric protein. Molecular and Cellular Biology. 11: 1523-30. PMID 1899909 DOI: 10.1128/Mcb.11.3.1523 |
0.622 |
|
| 1990 |
Reiss Y, Goldstein JL, Seabra MC, Casey PJ, Brown MS. Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides Cell. 62: 81-88. PMID 2194674 DOI: 10.1016/0092-8674(90)90242-7 |
0.384 |
|
| 1990 |
Hinton DR, Blanks JC, Fong HK, Casey PJ, Hildebrandt E, Simons MI. Novel localization of a G protein, Gz-alpha, in neurons of brain and retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 2763-70. PMID 2117645 DOI: 10.1523/Jneurosci.10-08-02763.1990 |
0.318 |
|
| 1990 |
Mumby SM, Casey PJ, Gilman AG, Gutowski S, Sternweis PC. G protein gamma subunits contain a 20-carbon isoprenoid. Proceedings of the National Academy of Sciences of the United States of America. 87: 5873-7. PMID 2116011 DOI: 10.1073/Pnas.87.15.5873 |
0.756 |
|
| 1990 |
Casey PJ, Fong HK, Simon MI, Gilman AG. Gz, a guanine nucleotide-binding protein with unique biochemical properties. The Journal of Biological Chemistry. 265: 2383-90. PMID 2105321 |
0.599 |
|
| 1990 |
Farnsworth CC, Casey PJ, Howald WN, Glomset JA, Gelb MH. Structural characterization of prenyl groups attached to proteins Methods. 1: 231-240. DOI: 10.1016/S1046-2023(05)80322-6 |
0.325 |
|
| 1989 |
Casey PJ, Solski PA, Der CJ, Buss JE. p21ras is modified by a farnesyl isoprenoid. Proceedings of the National Academy of Sciences of the United States of America. 86: 8323-7. PMID 2682646 DOI: 10.1073/Pnas.86.21.8323 |
0.387 |
|
| 1989 |
Freissmuth M, Casey PJ, Gilman AG. G proteins control diverse pathways of transmembrane signaling Faseb Journal. 3: 2125-2139. PMID 2546847 DOI: 10.1096/Fasebj.3.10.2546847 |
0.637 |
|
| 1989 |
Casey PJ, Graziano MP, Gilman AG. G protein beta gamma subunits from bovine brain and retina: equivalent catalytic support of ADP-ribosylation of alpha subunits by pertussis toxin but differential interactions with Gs alpha. Biochemistry. 28: 611-6. PMID 2496748 DOI: 10.1021/Bi00428A029 |
0.609 |
|
| 1988 |
Casey PJ, Graziano MP, Freissmuth M, Gilman AG. Role of G proteins in transmembrane signaling. Cold Spring Harbor Symposia On Quantitative Biology. 53: 203-8. PMID 3151167 DOI: 10.1101/Sqb.1988.053.01.026 |
0.645 |
|
| 1988 |
Casey PJ, Gilman AG. G protein involvement in receptor-effector coupling Journal of Biological Chemistry. 263: 2577-2580. PMID 2830256 |
0.553 |
|
| 1987 |
Buss JE, Mumby SM, Casey PJ, Gilman AG, Sefton BM. Myristoylated alpha subunits of guanine nucleotide-binding regulatory proteins. Proceedings of the National Academy of Sciences of the United States of America. 84: 7493-7. PMID 3118369 DOI: 10.1073/Pnas.84.21.7493 |
0.587 |
|
| 1987 |
Graziano MP, Casey PJ, Gilman AG. Expression of cDNAs for G proteins in Escherichia coli. Two forms of Gs alpha stimulate adenylate cyclase. The Journal of Biological Chemistry. 262: 11375-81. PMID 3112160 |
0.541 |
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