| Year |
Citation |
Score |
| 2022 |
Thurman AL, Li X, Villacreses R, Yu W, Gong H, Mather SE, Romano-Ibarra GS, Meyerholz DK, Stoltz DA, Welsh MJ, Thornell IM, Zabner J, Pezzulo AA. A Single-Cell Atlas of Large and Small Airways at Birth in a Porcine Model of Cystic Fibrosis. American Journal of Respiratory Cell and Molecular Biology. PMID 35235762 DOI: 10.1165/rcmb.2021-0499OC |
0.336 |
|
| 2021 |
Chen OG, Mather SE, Brommel CM, Hamilton BA, Ehler A, Villacreses R, Girgis RE, Abou Alaiwa M, Stoltz DA, Zabner J, Li X. Transduction of Pig Small Airway Epithelial Cells and Distal Lung Progenitor Cells by AAV4. Cells. 10. PMID 33923029 DOI: 10.3390/cells10051014 |
0.358 |
|
| 2021 |
Li X, Villacreses R, Thornell IM, Noriega J, Mather S, Brommel CM, Lu L, Zabner A, Ehler A, Meyerholz DK, Stoltz DA, Zabner J. V-type ATPase Mediates Airway Surface Liquid Acidification in Pig Small Airway Epithelial Cells. American Journal of Respiratory Cell and Molecular Biology. PMID 33789071 DOI: 10.1165/rcmb.2020-0349OC |
0.32 |
|
| 2019 |
Stapleton EM, Manges R, Parker G, Stone EA, Peters TM, Blount RJ, Noriega J, Li X, Zabner J, Polgreen PM, Chipara O, Herman T, Comellas AP. Indoor Particulate Matter From Smoker Homes Induces Bacterial Growth, Biofilm Formation, and Impairs Airway Antimicrobial Activity. A Pilot Study. Frontiers in Public Health. 7: 418. PMID 32039129 DOI: 10.3389/Fpubh.2019.00418 |
0.316 |
|
| 2019 |
Miller AC, Comellas AP, Hornick DB, Stoltz DA, Cavanaugh JE, Gerke AK, Welsh MJ, Zabner J, Polgreen PM. Cystic fibrosis carriers are at increased risk for a wide range of cystic fibrosis-related conditions. Proceedings of the National Academy of Sciences of the United States of America. PMID 31882447 DOI: 10.1073/Pnas.1914912117 |
0.316 |
|
| 2019 |
Singh S, Hornick D, Fedler J, Launspach JL, Teresi ME, Santacroce TR, Cavanaugh JE, Horan R, Nelson G, Starner TD, Zabner J, Durairaj L. Randomized controlled study of aerosolized hypertonic xylitol versus hypertonic saline in hospitalized patients with pulmonary exacerbation of cystic fibrosis. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. PMID 31327670 DOI: 10.1016/J.Jcf.2019.06.016 |
0.385 |
|
| 2019 |
Cooney AL, Thornell IM, Singh BK, Shah VS, Stoltz DA, McCray PB, Zabner J, Sinn PL. Novel AAV-mediated gene delivery system corrects CFTR function in pigs. American Journal of Respiratory Cell and Molecular Biology. PMID 31184507 DOI: 10.1165/Rcmb.2019-0006Oc |
0.478 |
|
| 2019 |
Hamilton BA, Li X, Pezzulo AA, Abou Alaiwa MH, Zabner J. Polarized AAVR expression determines infectivity by AAV gene therapy vectors. Gene Therapy. PMID 30962536 DOI: 10.1038/S41434-019-0078-3 |
0.412 |
|
| 2019 |
Pezzulo AA, Tudas RA, Stewart CG, Buonfiglio LGV, Lindsay BD, Taft PJ, Gansemer ND, Zabner J. HSP90 inhibitor geldanamycin reverts IL-13- and IL-17-induced airway goblet cell metaplasia. The Journal of Clinical Investigation. PMID 30640172 DOI: 10.1172/Jci123524 |
0.311 |
|
| 2018 |
Alaiwa MHA, Launspach JL, Grogan B, Carter S, Zabner J, Stoltz DA, Singh PK, McKone EF, Welsh MJ. Ivacaftor-induced sweat chloride reductions correlate with increases in airway surface liquid pH in cystic fibrosis. Jci Insight. 3. PMID 30089726 DOI: 10.1172/Jci.Insight.121468 |
0.376 |
|
| 2018 |
Vargas Buonfiglio LG, Borcherding JA, Frommelt M, Parker GJ, Duchman B, Vanegas Calderón OG, Fernandez-Ruiz R, Noriega JE, Stone EA, Gerke AK, Zabner J, Comellas AP. Airway surface liquid from smokers promotes bacterial growth and biofilm formation via iron-lactoferrin imbalance. Respiratory Research. 19: 42. PMID 29524964 DOI: 10.1186/S12931-018-0743-X |
0.302 |
|
| 2018 |
O'Malley Y, Rotti PG, Thornell IM, Vanegas Calderón OG, Febres-Aldana C, Durham K, Yao J, Li X, Zhu Z, Norris AW, Zabner J, Engelhardt JF, Uc A. DEVELOPMENT OF A POLARIZED PANCREATIC DUCTULAR CELL EPITHELIA FOR PHYSIOLOGICAL STUDIES. Journal of Applied Physiology (Bethesda, Md. : 1985). PMID 29517421 DOI: 10.1152/Japplphysiol.00043.2018 |
0.357 |
|
| 2018 |
Thornell IM, Li X, Tang XX, Brommel CM, Karp PH, Welsh MJ, Zabner J. Nominal carbonic anhydrase activity minimizes airway-surface liquid pH changes during breathing. Physiological Reports. 6. PMID 29380953 DOI: 10.14814/Phy2.13569 |
0.302 |
|
| 2018 |
Taher H, Bauer C, Abston E, Kaczka DW, Bhatt SP, Zabner J, Brower RG, Beichel RR, Eberlein M. Chest wall strapping increases expiratory airflow and detectable airway segments in computer tomographic scans of normal and obstructed lungs. Journal of Applied Physiology (Bethesda, Md. : 1985). PMID 29357485 DOI: 10.1152/Japplphysiol.00184.2017 |
0.325 |
|
| 2017 |
Dieninghoff D, Karagiannidis C, Straßmann S, Pieper M, Dammaschek S, Zabner J, Klingelhutz A, Windisch W, Brockmann M, Schildgen O, Schildgen V. Fatal HBoV-1 infection in adult female cystic fibrosis patient. Human Pathology (New York). 7: 51-52. PMID 32337159 DOI: 10.1016/J.Ehpc.2016.07.001 |
0.333 |
|
| 2017 |
Abston E, Comellas A, Reed RM, Kim V, Wise RA, Brower R, Fortis S, Beichel R, Bhatt S, Zabner J, Newell J, Hoffman EA, Eberlein M. Higher BMI is associated with higher expiratory airflow normalised for lung volume (FEF25-75/FVC) in COPD. Bmj Open Respiratory Research. 4: e000231. PMID 29071083 DOI: 10.1136/Bmjresp-2017-000231 |
0.313 |
|
| 2017 |
Li X, Vargas Buonfiglio LG, Adam RJ, Stoltz DA, Zabner J, Comellas AP. Cystic Fibrosis Transmembrane Conductance Regulator Potentiation as a Therapeutic Strategy for Pulmonary Edema: A Proof-of-Concept Study in Pigs. Critical Care Medicine. PMID 28953499 DOI: 10.1097/Ccm.0000000000002720 |
0.348 |
|
| 2017 |
Vargas Buonfiglio LG, Cano M, Pezzulo AA, Vanegas Calderon OG, Zabner J, Gerke AK, Comellas AP. Effect of vitamin D3 on the antimicrobial activity of human airway surface liquid: preliminary results of a randomised placebo-controlled double-blind trial. Bmj Open Respiratory Research. 4: e000211. PMID 28883932 DOI: 10.1136/Bmjresp-2017-000211 |
0.324 |
|
| 2017 |
Adam RJ, Abou Alaiwa MH, Bouzek DC, Cook DP, Gansemer ND, Taft PJ, Powers LS, Stroik MR, Hoegger MJ, McMenimen JD, Hoffman EA, Zabner J, Welsh MJ, Meyerholz DK, Stoltz DA. Postnatal Airway Growth in Cystic Fibrosis Piglets. Journal of Applied Physiology (Bethesda, Md. : 1985). jap.00263.2017. PMID 28620056 DOI: 10.1152/Japplphysiol.00263.2017 |
0.413 |
|
| 2016 |
Steines B, Dickey DD, Bergen J, Excoffon KJ, Weinstein JR, Li X, Yan Z, Alaiwa MH, Shah VS, Bouzek DC, Powers LS, Gansemer ND, Ostedgaard LS, Engelhardt JF, Stoltz DA, ... ... Zabner J, et al. CFTR gene transfer with AAV improves early cystic fibrosis pig phenotypes. Jci Insight. 1: e88728. PMID 27699238 DOI: 10.1172/Jci.Insight.88728 |
0.468 |
|
| 2016 |
Vargas Buonfiglio LG, Bagegni M, Borcherding JA, Sieren JC, Caraballo JC, Reger A, Zabner J, Li X, Comellas AP. Protein Kinase C Zeta Inhibitor Promotes Resolution of Bleomycin-induced Acute Lung Injury. American Journal of Respiratory Cell and Molecular Biology. PMID 27486964 DOI: 10.1165/Rcmb.2015-0006Oc |
0.317 |
|
| 2016 |
Alaiwa MH, Launspach JL, Sheets KA, Rivera JA, Gansemer ND, Taft PJ, Thorne PS, Welsh MJ, Stoltz DA, Zabner J. Repurposing tromethamine as inhaled therapy to treat CF airway disease. Jci Insight. 1. PMID 27390778 DOI: 10.1172/Jci.Insight.87535 |
0.36 |
|
| 2016 |
Bartlett JA, Ramachandran S, Wohlford-Lenane CL, Barker CK, Pezzulo AA, Zabner J, Welsh MJ, Meyerholz DK, Stoltz DA, McCray PB. Newborn Cystic Fibrosis Pigs Have a Blunted Early Response to an Inflammatory Stimulus. American Journal of Respiratory and Critical Care Medicine. PMID 27027566 DOI: 10.1164/Rccm.201510-2112Oc |
0.371 |
|
| 2016 |
Lee M, Vecchio-Pagán B, Sharma N, Waheed A, Li X, Raraigh KS, Robbins S, Han ST, Franca AL, Pellicore MJ, Evans TA, Arcara KM, Nguyen H, Luan S, Belchis D, ... ... Zabner J, et al. Loss of carbonic anhydrase XII function in individuals with elevated sweat chloride concentration and pulmonary airway disease. Human Molecular Genetics. PMID 26911677 DOI: 10.1093/Hmg/Ddw065 |
0.373 |
|
| 2016 |
Shah VS, Meyerholz DK, Tang XX, Reznikov L, Abou Alaiwa M, Ernst SE, Karp PH, Wohlford-Lenane CL, Heilmann KP, Leidinger MR, Allen PD, Zabner J, McCray PB, Ostedgaard LS, Stoltz DA, et al. Airway acidification initiates host defense abnormalities in cystic fibrosis mice. Science (New York, N.Y.). 351: 503-7. PMID 26823428 DOI: 10.1126/Science.Aad5589 |
0.438 |
|
| 2016 |
Li X, Tang XX, Vargas Buonfiglio LG, Comellas AP, Thornell IM, Ramachandran S, Karp PH, Taft PJ, Sheets K, Abou Alaiwa MH, Welsh MJ, Meyerholz DK, Stoltz DA, Zabner J. Electrolyte transport properties in distal small airways from cystic fibrosis pigs with implications for host defense. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00422.2015. PMID 26801568 DOI: 10.1152/Ajplung.00422.2015 |
0.438 |
|
| 2016 |
Bruse S, Moreau M, Bromberg Y, Jang JH, Wang N, Ha H, Picchi M, Lin Y, Langley RJ, Qualls C, Klensney-Tait J, Zabner J, Leng S, Mao J, Belinsky SA, et al. Whole exome sequencing identifies novel candidate genes that modify chronic obstructive pulmonary disease susceptibility. Human Genomics. 10: 1. PMID 26744305 DOI: 10.1186/S40246-015-0058-7 |
0.305 |
|
| 2015 |
Du K, Karp PH, Ackerley C, Zabner J, Keshavjee S, Cutz E, Yeger H. Aggregates of mutant CFTR fragments in airway epithelial cells of CF lungs: new pathologic observations. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. 14: 182-93. PMID 25453871 DOI: 10.1016/J.Jcf.2014.09.012 |
0.44 |
|
| 2015 |
Chang EH, Tang XX, Shah VS, Launspach JL, Ernst SE, Hilkin B, Karp PH, Abou Alaiwa MH, Graham SM, Hornick DB, Welsh MJ, Stoltz DA, Zabner J. Medical reversal of chronic sinusitis in a cystic fibrosis patient with ivacaftor. International Forum of Allergy & Rhinology. 5: 178-81. PMID 25363320 DOI: 10.1002/Alr.21440 |
0.345 |
|
| 2015 |
Jaffer OA, Carter AB, Sanders PN, Dibbern ME, Winters CJ, Murthy S, Ryan AJ, Rokita AG, Prasad AM, Zabner J, Kline JN, Grumbach IM, Anderson ME. Mitochondrial-targeted antioxidant therapy decreases transforming growth factor-β-mediated collagen production in a murine asthma model. American Journal of Respiratory Cell and Molecular Biology. 52: 106-15. PMID 24988374 DOI: 10.1165/Rcmb.2013-0519Oc |
0.322 |
|
| 2014 |
Abou Alaiwa MH, Reznikov LR, Gansemer ND, Sheets KA, Horswill AR, Stoltz DA, Zabner J, Welsh MJ. pH modulates the activity and synergism of the airway surface liquid antimicrobials β-defensin-3 and LL-37. Proceedings of the National Academy of Sciences of the United States of America. 111: 18703-8. PMID 25512526 DOI: 10.1073/Pnas.1422091112 |
0.334 |
|
| 2014 |
Hoegger MJ, Fischer AJ, McMenimen JD, Ostedgaard LS, Tucker AJ, Awadalla MA, Moninger TO, Michalski AS, Hoffman EA, Zabner J, Stoltz DA, Welsh MJ. Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis. Science (New York, N.Y.). 345: 818-22. PMID 25124441 DOI: 10.1126/Science.1255825 |
0.413 |
|
| 2014 |
Abou Alaiwa MH, Beer AM, Pezzulo AA, Launspach JL, Horan RA, Stoltz DA, Starner TD, Welsh MJ, Zabner J. Neonates with cystic fibrosis have a reduced nasal liquid pH; a small pilot study. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. 13: 373-7. PMID 24418186 DOI: 10.1016/J.Jcf.2013.12.006 |
0.361 |
|
| 2014 |
Pezzulo AA, Nassar BS, Gansemer ND, Rutland CJ, Stoltz DA, Zabner J. Abundance of DNase-Susceptible Bacterial DNA from Damaged Cells in the Lungs of Pigs Annals of the American Thoracic Society. 11. DOI: 10.1513/Annalsats.201307-235Mg |
0.32 |
|
| 2013 |
Li X, Rossen N, Sinn PL, Hornick AL, Steines BR, Karp PH, Ernst SE, Adam RJ, Moninger TO, Levasseur DN, Zabner J. Integrin α6β4 identifies human distal lung epithelial progenitor cells with potential as a cell-based therapy for cystic fibrosis lung disease. Plos One. 8: e83624. PMID 24349537 DOI: 10.1371/Journal.Pone.0083624 |
0.41 |
|
| 2013 |
Sanders PN, Koval OM, Jaffer OA, Prasad AM, Businga TR, Scott JA, Hayden PJ, Luczak ED, Dickey DD, Allamargot C, Olivier AK, Meyerholz DK, Robison AJ, Winder DG, Blackwell TS, ... ... Zabner J, et al. CaMKII is essential for the proasthmatic effects of oxidation. Science Translational Medicine. 5: 195ra97. PMID 23884469 DOI: 10.1126/Scitranslmed.3006135 |
0.33 |
|
| 2013 |
Pezzulo AA, Kelly PH, Nassar BS, Rutland CJ, Gansemer ND, Dohrn CL, Costello AJ, Stoltz DA, Zabner J. Abundant DNase I-sensitive bacterial DNA in healthy porcine lungs and its implications for the lung microbiome. Applied and Environmental Microbiology. 79: 5936-41. PMID 23872563 DOI: 10.1128/Aem.01752-13 |
0.348 |
|
| 2013 |
Bartlett JA, Albertolle ME, Wohlford-Lenane C, Pezzulo AA, Zabner J, Niles RK, Fisher SJ, McCray PB, Williams KE. Protein composition of bronchoalveolar lavage fluid and airway surface liquid from newborn pigs. American Journal of Physiology. Lung Cellular and Molecular Physiology. 305: L256-66. PMID 23709621 DOI: 10.1152/Ajplung.00056.2013 |
0.365 |
|
| 2013 |
Stoltz DA, Rokhlina T, Ernst SE, Pezzulo AA, Ostedgaard LS, Karp PH, Samuel MS, Reznikov LR, Rector MV, Gansemer ND, Bouzek DC, Alaiwa MH, Hoegger MJ, Ludwig PS, Taft PJ, ... ... Zabner J, et al. Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs. The Journal of Clinical Investigation. 123: 2685-93. PMID 23676501 DOI: 10.1172/Jci68867 |
0.387 |
|
| 2013 |
Potash AE, Wallen TJ, Karp PH, Ernst S, Moninger TO, Gansemer ND, Stoltz DA, Zabner J, Chang EH. Adenoviral gene transfer corrects the ion transport defect in the sinus epithelia of a porcine CF model. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 947-53. PMID 23511247 DOI: 10.1038/Mt.2013.49 |
0.42 |
|
| 2013 |
Borcherding JA, Chen H, Caraballo JC, Baltrusaitis J, Pezzulo AA, Zabner J, Grassian VH, Comellas AP. Coal fly ash impairs airway antimicrobial peptides and increases bacterial growth. Plos One. 8: e57673. PMID 23469047 DOI: 10.1371/Journal.Pone.0057673 |
0.338 |
|
| 2013 |
Klesney-Tait J, Keck K, Li X, Gilfillan S, Otero K, Baruah S, Meyerholz DK, Varga SM, Knudson CJ, Moninger TO, Moreland J, Zabner J, Colonna M. Transepithelial migration of neutrophils into the lung requires TREM-1. The Journal of Clinical Investigation. 123: 138-49. PMID 23241959 DOI: 10.1172/Jci64181 |
0.409 |
|
| 2012 |
Pezzulo AA, Hornick EE, Rector MV, Estin M, Reisetter AC, Taft PJ, Butcher SC, Carter AB, Manak JR, Stoltz DA, Zabner J. Expression of human paraoxonase 1 decreases superoxide levels and alters bacterial colonization in the gut of Drosophila melanogaster. Plos One. 7: e43777. PMID 22952763 DOI: 10.1371/Journal.Pone.0043777 |
0.349 |
|
| 2012 |
Pezzulo AA, Tang XX, Hoegger MJ, Alaiwa MH, Ramachandran S, Moninger TO, Karp PH, Wohlford-Lenane CL, Haagsman HP, van Eijk M, Bánfi B, Horswill AR, Stoltz DA, McCray PB, Welsh MJ, ... Zabner J, et al. Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung. Nature. 487: 109-13. PMID 22763554 DOI: 10.1038/Nature11130 |
0.442 |
|
| 2012 |
Chang EH, Pezzulo AA, Meyerholz DK, Potash AE, Wallen TJ, Reznikov LR, Sieren JC, Karp PH, Ernst S, Moninger TO, Gansemer ND, McCray PB, Stoltz DA, Welsh MJ, Zabner J. Sinus hypoplasia precedes sinus infection in a porcine model of cystic fibrosis. The Laryngoscope. 122: 1898-905. PMID 22711071 DOI: 10.1002/Lary.23392 |
0.394 |
|
| 2012 |
Li X, Comellas AP, Karp PH, Ernst SE, Moninger TO, Gansemer ND, Taft PJ, Pezzulo AA, Rector MV, Rossen N, Stoltz DA, McCray PB, Welsh MJ, Zabner J. CFTR is required for maximal transepithelial liquid transport in pig alveolar epithelia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 303: L152-60. PMID 22637155 DOI: 10.1152/Ajplung.00116.2012 |
0.356 |
|
| 2012 |
Dickey DD, Excoffon KJ, Young KR, Parekh KR, Zabner J. Hoechst increases adeno-associated virus-mediated transgene expression in airway epithelia by inducing the cytomegalovirus promoter. The Journal of Gene Medicine. 14: 366-73. PMID 22610695 DOI: 10.1002/Jgm.2632 |
0.331 |
|
| 2012 |
Lacruz RS, Smith CE, Moffatt P, Chang EH, Bromage TG, Bringas P, Nanci A, Baniwal SK, Zabner J, Welsh MJ, Kurtz I, Paine ML. Requirements for ion and solute transport, and pH regulation during enamel maturation. Journal of Cellular Physiology. 227: 1776-85. PMID 21732355 DOI: 10.1002/Jcp.22911 |
0.342 |
|
| 2011 |
Pezzulo AA, Asif MH, Willander M, Zabner J. In Situ Quantification of Glucose Concentration in Airway Surface Liquid With Functionalized ZnO Nanorod-Coated Microelectrodes. Journal of Analytical & Bioanalytical Techniques. PMID 23227447 DOI: 10.4172/2155-9872.S7-002 |
0.33 |
|
| 2011 |
Dickey DD, Excoffon KJ, Koerber JT, Bergen J, Steines B, Klesney-Tait J, Schaffer DV, Zabner J. Enhanced sialic acid-dependent endocytosis explains the increased efficiency of infection of airway epithelia by a novel adeno-associated virus. Journal of Virology. 85: 9023-30. PMID 21697483 DOI: 10.1128/Jvi.05154-11 |
0.316 |
|
| 2011 |
Itani OA, Chen JH, Karp PH, Ernst S, Keshavjee S, Parekh K, Klesney-Tait J, Zabner J, Welsh MJ. Human cystic fibrosis airway epithelia have reduced Cl- conductance but not increased Na+ conductance. Proceedings of the National Academy of Sciences of the United States of America. 108: 10260-5. PMID 21646513 DOI: 10.1073/Pnas.1106695108 |
0.394 |
|
| 2011 |
Chang EH, Lacruz RS, Bromage TG, Bringas P, Welsh MJ, Zabner J, Paine ML. Enamel pathology resulting from loss of function in the cystic fibrosis transmembrane conductance regulator in a porcine animal model. Cells, Tissues, Organs. 194: 249-54. PMID 21525720 DOI: 10.1159/000324248 |
0.39 |
|
| 2011 |
Ostedgaard LS, Meyerholz DK, Chen JH, Pezzulo AA, Karp PH, Rokhlina T, Ernst SE, Hanfland RA, Reznikov LR, Ludwig PS, Rogan MP, Davis GJ, Dohrn CL, Wohlford-Lenane C, Taft PJ, ... ... Zabner J, et al. The ΔF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs. Science Translational Medicine. 3: 74ra24. PMID 21411740 DOI: 10.1126/Scitranslmed.3001868 |
0.328 |
|
| 2011 |
Lorentzen D, Durairaj L, Pezzulo AA, Nakano Y, Launspach J, Stoltz DA, Zamba G, McCray PB, Zabner J, Welsh MJ, Nauseef WM, Bánfi B. Concentration of the antibacterial precursor thiocyanate in cystic fibrosis airway secretions. Free Radical Biology & Medicine. 50: 1144-50. PMID 21334431 DOI: 10.1016/J.Freeradbiomed.2011.02.013 |
0.423 |
|
| 2011 |
Pezzulo AA, Gutiérrez J, Duschner KS, McConnell KS, Taft PJ, Ernst SE, Yahr TL, Rahmouni K, Klesney-Tait J, Stoltz DA, Zabner J. Glucose depletion in the airway surface liquid is essential for sterility of the airways. Plos One. 6: e16166. PMID 21311590 DOI: 10.1371/Journal.Pone.0016166 |
0.37 |
|
| 2011 |
Chang EH, Pezzulo AA, Zabner J. Do cell junction protein mutations cause an airway phenotype in mice or humans? American Journal of Respiratory Cell and Molecular Biology. 45: 202-20. PMID 21297078 DOI: 10.1165/Rcmb.2010-0498Tr |
0.369 |
|
| 2011 |
Pezzulo AA, Starner TD, Scheetz TE, Traver GL, Tilley AE, Harvey BG, Crystal RG, McCray PB, Zabner J. The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 300: L25-31. PMID 20971803 DOI: 10.1152/Ajplung.00256.2010 |
0.377 |
|
| 2010 |
Chen JH, Stoltz DA, Karp PH, Ernst SE, Pezzulo AA, Moninger TO, Rector MV, Reznikov LR, Launspach JL, Chaloner K, Zabner J, Welsh MJ. Loss of anion transport without increased sodium absorption characterizes newborn porcine cystic fibrosis airway epithelia. Cell. 143: 911-23. PMID 21145458 DOI: 10.1016/J.Cell.2010.11.029 |
0.404 |
|
| 2010 |
Rogan MP, Reznikov LR, Pezzulo AA, Gansemer ND, Samuel M, Prather RS, Zabner J, Fredericks DC, McCray PB, Welsh MJ, Stoltz DA. Pigs and humans with cystic fibrosis have reduced insulin-like growth factor 1 (IGF1) levels at birth. Proceedings of the National Academy of Sciences of the United States of America. 107: 20571-5. PMID 21059918 DOI: 10.1073/Pnas.1015281107 |
0.336 |
|
| 2010 |
Meyerholz DK, Stoltz DA, Namati E, Ramachandran S, Pezzulo AA, Smith AR, Rector MV, Suter MJ, Kao S, McLennan G, Tearney GJ, Zabner J, McCray PB, Welsh MJ. Loss of cystic fibrosis transmembrane conductance regulator function produces abnormalities in tracheal development in neonatal pigs and young children. American Journal of Respiratory and Critical Care Medicine. 182: 1251-61. PMID 20622026 DOI: 10.1164/Rccm.201004-0643Oc |
0.366 |
|
| 2010 |
Stoltz DA, Meyerholz DK, Pezzulo AA, Ramachandran S, Rogan MP, Davis GJ, Hanfland RA, Wohlford-Lenane C, Dohrn CL, Bartlett JA, Nelson GA, Chang EH, Taft PJ, Ludwig PS, Estin M, ... ... Zabner J, et al. Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth. Science Translational Medicine. 2: 29ra31. PMID 20427821 DOI: 10.1126/Scitranslmed.3000928 |
0.422 |
|
| 2010 |
Excoffon KJ, Gansemer ND, Mobily ME, Karp PH, Parekh KR, Zabner J. Isoform-specific regulation and localization of the coxsackie and adenovirus receptor in human airway epithelia. Plos One. 5: e9909. PMID 20361046 DOI: 10.1371/Journal.Pone.0009909 |
0.374 |
|
| 2010 |
Chang EH, Lee JH, Zabner J. Tryptase does not alter transepithelial conductance or paracellular permeability in human airway epithelial cells. American Journal of Rhinology & Allergy. 24: 126-8. PMID 20338110 DOI: 10.2500/Ajra.2010.24.3442 |
0.399 |
|
| 2010 |
Estin ML, Stoltz DA, Zabner J. Paraoxonase 1, quorum sensing, and P. aeruginosa infection: A novel model Advances in Experimental Medicine and Biology. 660: 183-193. PMID 20221881 DOI: 10.1007/978-1-60761-350-3_17 |
0.348 |
|
| 2010 |
Granio O, Ashbourne Excoffon KJ, Henning P, Melin P, Norez C, Gonzalez G, Karp PH, Magnusson MK, Habib N, Lindholm L, Becq F, Boulanger P, Zabner J, Hong SS. Adenovirus 5-fiber 35 chimeric vector mediates efficient apical correction of the cystic fibrosis transmembrane conductance regulator defect in cystic fibrosis primary airway epithelia. Human Gene Therapy. 21: 251-69. PMID 19788389 DOI: 10.1089/Hum.2009.056 |
0.43 |
|
| 2010 |
Stoltz D, Pezzulo A, Zabner J. Role of CFTR on Sinus Development and Disease in the CF Pig Otolaryngology-Head and Neck Surgery. 143. DOI: 10.1016/J.Otohns.2010.06.734 |
0.327 |
|
| 2009 |
Stoltz DA, Ozer EA, Recker TJ, Estin M, Yang X, Shih DM, Lusis AJ, Zabner J. A common mutation in paraoxonase-2 results in impaired lactonase activity. The Journal of Biological Chemistry. 284: 35564-71. PMID 19840942 DOI: 10.1074/Jbc.M109.051706 |
0.558 |
|
| 2009 |
Vermeer PD, Denker J, Estin M, Moninger TO, Keshavjee S, Karp P, Kline JN, Zabner J. MMP9 modulates tight junction integrity and cell viability in human airway epithelia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 296: L751-62. PMID 19270179 DOI: 10.1152/Ajplung.90578.2008 |
0.305 |
|
| 2009 |
Excoffon KJ, Koerber JT, Dickey DD, Murtha M, Keshavjee S, Kaspar BK, Zabner J, Schaffer DV. Directed evolution of adeno-associated virus to an infectious respiratory virus. Proceedings of the National Academy of Sciences of the United States of America. 106: 3865-70. PMID 19237554 DOI: 10.1073/Pnas.0813365106 |
0.355 |
|
| 2009 |
Gonzalez G, Granio O, Ashbourne-Excoffon KJ, Henning P, Melin P, Norez C, Karp PH, Lindholm L, Becq F, Boulanger P, Zabner J, Hong SS. The Adenovirus chimeric vector Ad5F35/GFP-CFTR efficiently restores the CFTR deficiency in human airway epithelia via apical surface transduction Journal of Cystic Fibrosis. 8. DOI: 10.1016/S1569-1993(09)60122-3 |
0.393 |
|
| 2008 |
Rogers CS, Stoltz DA, Meyerholz DK, Ostedgaard LS, Rokhlina T, Taft PJ, Rogan MP, Pezzulo AA, Karp PH, Itani OA, Kabel AC, Wohlford-Lenane CL, Davis GJ, Hanfland RA, Smith TL, ... ... Zabner J, et al. Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs. Science (New York, N.Y.). 321: 1837-41. PMID 18818360 DOI: 10.1126/Science.1163600 |
0.416 |
|
| 2008 |
Stoltz DA, Ozer EA, Taft PJ, Barry M, Liu L, Kiss PJ, Moninger TO, Parsek MR, Zabner J. Drosophila are protected from Pseudomonas aeruginosa lethality by transgenic expression of paraoxonase-1. The Journal of Clinical Investigation. 118: 3123-31. PMID 18704198 DOI: 10.1172/Jci35147 |
0.614 |
|
| 2008 |
Rogers CS, Abraham WM, Brogden KA, Engelhardt JF, Fisher JT, McCray PB, McLennan G, Meyerholz DK, Namati E, Ostedgaard LS, Prather RS, Sabater JR, Stoltz DA, Zabner J, Welsh MJ. The porcine lung as a potential model for cystic fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 295: L240-63. PMID 18487356 DOI: 10.1152/Ajplung.90203.2008 |
0.42 |
|
| 2008 |
Excoffon KJ, Guglielmi KM, Wetzel JD, Gansemer ND, Campbell JA, Dermody TS, Zabner J. Reovirus preferentially infects the basolateral surface and is released from the apical surface of polarized human respiratory epithelial cells. The Journal of Infectious Diseases. 197: 1189-97. PMID 18419529 DOI: 10.1086/529515 |
0.352 |
|
| 2007 |
Granio O, Norez C, Ashbourne Excoffon KJ, Karp PH, Lusky M, Becq F, Boulanger P, Zabner J, Hong SS. Cellular localization and activity of Ad-delivered GFP-CFTR in airway epithelial and tracheal cells. American Journal of Respiratory Cell and Molecular Biology. 37: 631-9. PMID 17641299 DOI: 10.1165/Rcmb.2007-0026Te |
0.416 |
|
| 2007 |
Vermeer PD, McHugh J, Rokhlina T, Vermeer DW, Zabner J, Welsh MJ. Vaccinia virus entry, exit, and interaction with differentiated human airway epithelia. Journal of Virology. 81: 9891-9. PMID 17581984 DOI: 10.1128/Jvi.00601-07 |
0.324 |
|
| 2007 |
Excoffon KJ, Gansemer N, Traver G, Zabner J. Functional effects of coxsackievirus and adenovirus receptor glycosylation on homophilic adhesion and adenoviral infection. Journal of Virology. 81: 5573-8. PMID 17376928 DOI: 10.1128/Jvi.02562-06 |
0.315 |
|
| 2007 |
Stoltz DA, Ozer EA, Ng CJ, Yu JM, Reddy ST, Lusis AJ, Bourquard N, Parsek MR, Zabner J, Shih DM. Paraoxonase-2 deficiency enhances Pseudomonas aeruginosa quorum sensing in murine tracheal epithelia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L852-60. PMID 17122353 DOI: 10.1152/Ajplung.00370.2006 |
0.646 |
|
| 2007 |
Moskwa P, Lorentzen D, Excoffon KJ, Zabner J, McCray PB, Nauseef WM, Dupuy C, Bánfi B. A novel host defense system of airways is defective in cystic fibrosis. American Journal of Respiratory and Critical Care Medicine. 175: 174-83. PMID 17082494 DOI: 10.1164/Rccm.200607-1029Oc |
0.397 |
|
| 2007 |
Durairaj L, Launspach J, Watt JL, Mohamad Z, Kline J, Zabner J. Safety assessment of inhaled xylitol in subjects with cystic fibrosis. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. 6: 31-4. PMID 16781897 DOI: 10.1016/J.Jcf.2006.05.002 |
0.308 |
|
| 2006 |
Excoffon KJ, Avenarius MR, Hansen MR, Kimberling WJ, Najmabadi H, Smith RJ, Zabner J. The Coxsackievirus and Adenovirus Receptor: a new adhesion protein in cochlear development. Hearing Research. 215: 1-9. PMID 16678988 DOI: 10.1016/J.Heares.2006.02.009 |
0.331 |
|
| 2006 |
Durairaj L, Neelakantan S, Launspach J, Watt JL, Allaman MM, Kearney WR, Veng-Pedersen P, Zabner J. Bronchoscopic assessment of airway retention time of aerosolized xylitol. Respiratory Research. 7: 27. PMID 16483382 DOI: 10.1186/1465-9921-7-27 |
0.344 |
|
| 2006 |
Keriel A, René C, Galer C, Zabner J, Kremer EJ. Canine adenovirus vectors for lung-directed gene transfer: efficacy, immune response, and duration of transgene expression using helper-dependent vectors. Journal of Virology. 80: 1487-96. PMID 16415025 DOI: 10.1128/Jvi.80.3.1487-1496.2006 |
0.406 |
|
| 2006 |
Seiler MP, Miller AD, Zabner J, Halbert CL. Adeno-associated virus types 5 and 6 use distinct receptors for cell entry. Human Gene Therapy. 17: 10-9. PMID 16409121 DOI: 10.1089/Hum.2006.17.10 |
0.377 |
|
| 2005 |
Ozer EA, Pezzulo A, Shih DM, Chun C, Furlong C, Lusis AJ, Greenberg EP, Zabner J. Human and murine paraoxonase 1 are host modulators of Pseudomonas aeruginosa quorum-sensing. Fems Microbiology Letters. 253: 29-37. PMID 16260097 DOI: 10.1016/J.Femsle.2005.09.023 |
0.593 |
|
| 2005 |
Suter M, Reinhardt J, Montague P, Taft P, Lee J, Zabner J, McLennan G. Bronchoscopic imaging of pulmonary mucosal vasculature responses to inflammatory mediators. Journal of Biomedical Optics. 10: 034013. PMID 16229657 DOI: 10.1117/1.1924714 |
0.301 |
|
| 2005 |
Farmen SL, Karp PH, Ng P, Palmer DJ, Koehler DR, Hu J, Beaudet AL, Zabner J, Welsh MJ. Gene transfer of CFTR to airway epithelia: low levels of expression are sufficient to correct Cl- transport and overexpression can generate basolateral CFTR. American Journal of Physiology. Lung Cellular and Molecular Physiology. 289: L1123-30. PMID 16085675 DOI: 10.1152/Ajplung.00049.2005 |
0.426 |
|
| 2005 |
Zabner J, Scheetz TE, Almabrazi HG, Casavant TL, Huang J, Keshavjee S, McCray PB. CFTR DeltaF508 mutation has minimal effect on the gene expression profile of differentiated human airway epithelia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 289: L545-53. PMID 15937068 DOI: 10.1152/Ajplung.00065.2005 |
0.418 |
|
| 2005 |
Mutlu GM, Adir Y, Jameel M, Akhmedov AT, Welch L, Dumasius V, Meng FJ, Zabner J, Koenig C, Lewis ER, Balagani R, Traver G, Sznajder JI, Factor P. Interdependency of beta-adrenergic receptors and CFTR in regulation of alveolar active Na+ transport. Circulation Research. 96: 999-1005. PMID 15802612 DOI: 10.1161/01.Res.0000164554.21993.Ac |
0.369 |
|
| 2005 |
Excoffon KJ, Traver GL, Zabner J. The role of the extracellular domain in the biology of the coxsackievirus and adenovirus receptor. American Journal of Respiratory Cell and Molecular Biology. 32: 498-503. PMID 15778494 DOI: 10.1165/Rcmb.2005-0031Oc |
0.309 |
|
| 2005 |
Dajani R, Zhang Y, Taft PJ, Travis SM, Starner TD, Olsen A, Zabner J, Welsh MJ, Engelhardt JF. Lysozyme secretion by submucosal glands protects the airway from bacterial infection. American Journal of Respiratory Cell and Molecular Biology. 32: 548-52. PMID 15746432 DOI: 10.1165/Rcmb.2005-0059Oc |
0.414 |
|
| 2005 |
Ostedgaard LS, Rokhlina T, Karp PH, Lashmit P, Afione S, Schmidt M, Zabner J, Stinski MF, Chiorini JA, Welsh MJ. A shortened adeno-associated virus expression cassette for CFTR gene transfer to cystic fibrosis airway epithelia. Proceedings of the National Academy of Sciences of the United States of America. 102: 2952-7. PMID 15703296 DOI: 10.1073/Pnas.0409845102 |
0.438 |
|
| 2005 |
Gelbman BD, Heguy A, O'Connor TP, Zabner J, Crystal RG. 814. Adenovirus-Mediated Gene Transfer Demonstrates That Pirin, a Transcription Factor Up-Regulated in the Bronchial Epithelium by Cigarette Smoke, Mediates Bronchial Epithelial Cell Apoptosis Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.351 |
0.381 |
|
| 2004 |
Zhang LN, Karp P, Gerard CJ, Pastor E, Laux D, Munson K, Yan Z, Liu X, Godwin S, Thomas CP, Zabner J, Shi H, Caldwell CW, Peluso R, Carter B, et al. Dual therapeutic utility of proteasome modulating agents for pharmaco-gene therapy of the cystic fibrosis airway. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 990-1002. PMID 15564131 DOI: 10.1016/J.Ymthe.2004.08.009 |
0.422 |
|
| 2004 |
Brown CL, Graham SM, Cable BB, Ozer EA, Taft PJ, Zabner J. Xylitol enhances bacterial killing in the rabbit maxillary sinus. The Laryngoscope. 114: 2021-4. PMID 15510034 DOI: 10.1097/01.Mlg.0000147939.90249.47 |
0.575 |
|
| 2004 |
Davis B, Nguyen J, Stoltz D, Depping D, Excoffon KJ, Zabner J. Adenovirus-mediated erythropoietin production by airway epithelia is enhanced by apical localization of the coxsackie-adenovirus receptor in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 500-6. PMID 15336650 DOI: 10.1016/J.Ymthe.2004.05.032 |
0.414 |
|
| 2004 |
Excoffon KJ, Hruska-Hageman A, Klotz M, Traver GL, Zabner J. A role for the PDZ-binding domain of the coxsackie B virus and adenovirus receptor (CAR) in cell adhesion and growth. Journal of Cell Science. 117: 4401-9. PMID 15304526 DOI: 10.1242/Jcs.01300 |
0.331 |
|
| 2004 |
Ackermann MR, Gallup JM, Zabner J, Evans RB, Brockus CW, Meyerholz DK, Grubor B, Brogden KA. Differential expression of sheep beta-defensin-1 and -2 and interleukin 8 during acute Mannheimia haemolytica pneumonia. Microbial Pathogenesis. 37: 21-7. PMID 15194156 DOI: 10.1016/J.Micpath.2004.04.003 |
0.318 |
|
| 2004 |
Chun CK, Ozer EA, Welsh MJ, Zabner J, Greenberg EP. Inactivation of a Pseudomonas aeruginosa quorum-sensing signal by human airway epithelia. Proceedings of the National Academy of Sciences of the United States of America. 101: 3587-90. PMID 14970327 DOI: 10.1073/Pnas.0308750101 |
0.622 |
|
| 2004 |
Scheetz TE, Zabner J, Welsh MJ, Coco J, Eyestone Mde F, Bonaldo M, Kucaba T, Casavant TL, Soares MB, McCray PB. Large-scale gene discovery in human airway epithelia reveals novel transcripts. Physiological Genomics. 17: 69-77. PMID 14701920 DOI: 10.1152/Physiolgenomics.00188.2003 |
0.407 |
|
| 2004 |
Zhou J, You Y, Zabner J, Ryan AJ, Mallampalli RK. The CCT promoter directs high-level transgene expression in distal lung epithelial cell lines. American Journal of Respiratory Cell and Molecular Biology. 30: 61-8. PMID 12829450 DOI: 10.1165/Rcmb.2003-0020Oc |
0.365 |
|
| 2004 |
You Y, Huang T, Richer EJ, Schmidt JE, Zabner J, Borok Z, Brody SL. Role of f-box factor foxj1 in differentiation of ciliated airway epithelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L650-7. PMID 12818891 DOI: 10.1152/Ajplung.00170.2003 |
0.332 |
|
| 2004 |
Lee KB, Saltzman CL, Taft P, Klotz M, Zabner J. 765. The Efficacy of Adenovirus Vector-Mediated Gene Transfer into Human Osteoblasts In Vitro and Osseous Tissue In Vivo Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.680 |
0.33 |
|
| 2004 |
Ozer EA, Zabner J. 566. Inactivation of a Bacterial Quorum-Sensing Signal by Expression of Bacterial Autoinducer Inhibitor, aiiA, in Mammalian Cells Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.490 |
0.619 |
|
| 2004 |
Farmen SL, Karp PH, Ng P, Koehler DR, Hu J, Zabner J, Welsh MJ. 110. Helper-Dependent Adenovirus with the Cytokeratin-18 Promoter Produces Greater Transepithelial Chloride Current and More Persistent Transgene Expression Than the CMV Promoter in Differentiated Human Airway Epithelia Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.047 |
0.386 |
|
| 2003 |
Huang T, You Y, Spoor MS, Richer EJ, Kudva VV, Paige RC, Seiler MP, Liebler JM, Zabner J, Plopper CG, Brody SL. Foxj1 is required for apical localization of ezrin in airway epithelial cells. Journal of Cell Science. 116: 4935-45. PMID 14625387 DOI: 10.1242/Jcs.00830 |
0.335 |
|
| 2003 |
Zabner J, Winter M, Excoffon KJ, Stoltz D, Ries D, Shasby S, Shasby M. Histamine alters E-cadherin cell adhesion to increase human airway epithelial permeability. Journal of Applied Physiology (Bethesda, Md. : 1985). 95: 394-401. PMID 12794099 DOI: 10.1152/Japplphysiol.01134.2002 |
0.353 |
|
| 2003 |
Zabner J, Karp P, Seiler M, Phillips SL, Mitchell CJ, Saavedra M, Welsh M, Klingelhutz AJ. Development of cystic fibrosis and noncystic fibrosis airway cell lines. American Journal of Physiology. Lung Cellular and Molecular Physiology. 284: L844-54. PMID 12676769 DOI: 10.1152/Ajplung.00355.2002 |
0.389 |
|
| 2003 |
Vermeer PD, Einwalter LA, Moninger TO, Rokhlina T, Kern JA, Zabner J, Welsh MJ. Segregation of receptor and ligand regulates activation of epithelial growth factor receptor. Nature. 422: 322-6. PMID 12646923 DOI: 10.1038/Nature01440 |
0.312 |
|
| 2003 |
Vermeer PD, Harson R, Einwalter LA, Moninger T, Zabner J. Interleukin-9 induces goblet cell hyperplasia during repair of human airway epithelia. American Journal of Respiratory Cell and Molecular Biology. 28: 286-95. PMID 12594054 DOI: 10.1165/Rcmb.4887 |
0.323 |
|
| 2002 |
Rooney CP, Suter M, McLenna G, Donnelley M, Reinhardt J, Delsing A, Hoffman EA, Zabner J. Laser fluorescence bronchoscopy for detection of fluorescent reporter genes in airway epithelia Gene Therapy. 9: 1639-1644. PMID 12424617 DOI: 10.1038/Sj.Gt.3301825 |
0.311 |
|
| 2002 |
Aldallal N, McNaughton EE, Manzel LJ, Richards AM, Zabner J, Ferkol TW, Look DC. Inflammatory response in airway epithelial cells isolated from patients with cystic fibrosis. American Journal of Respiratory and Critical Care Medicine. 166: 1248-56. PMID 12403695 DOI: 10.1164/Rccm.200206-627Oc |
0.408 |
|
| 2002 |
Walters RW, Freimuth P, Moninger TO, Ganske I, Zabner J, Welsh MJ. Adenovirus fiber disrupts CAR-mediated intercellular adhesion allowing virus escape. Cell. 110: 789-99. PMID 12297051 DOI: 10.1016/S0092-8674(02)00912-1 |
0.321 |
|
| 2002 |
Rooney CP, Denning GM, Davis BP, Flaherty DM, Chiorini JA, Zabner J. Bronchoalveolar fluid is not a major hindrance to virus-mediated gene therapy in cystic fibrosis Journal of Virology. 76: 10437-10443. PMID 12239320 DOI: 10.1128/Jvi.76.20.10437-10443.2002 |
0.441 |
|
| 2002 |
Seiler MP, Luner P, Moninger TO, Karp PH, Keshavjee S, Zabner J. Thixotropic solutions enhance viral-mediated gene transfer to airway epithelia. American Journal of Respiratory Cell and Molecular Biology. 27: 133-40. PMID 12151304 DOI: 10.1165/Ajrcmb.27.2.4793 |
0.386 |
|
| 2002 |
Graham SM, Scott SN, Launspach J, Zabner J. The effects of fluticasone propionate on nasal epithelial potential difference. American Journal of Rhinology. 16: 145-9. PMID 12141771 DOI: 10.1177/194589240201600304 |
0.342 |
|
| 2002 |
Glasspool-Malone J, Steenland PR, McDonald RJ, Sanchez RA, Watts TL, Zabner J, Malone RW. DNA transfection of macaque and murine respiratory tissue is greatly enhanced by use of a nuclease inhibitor. The Journal of Gene Medicine. 4: 323-2. PMID 12112649 DOI: 10.1002/Jgm.259 |
0.307 |
|
| 2002 |
Walters RW, Pilewski JM, Chiorini JA, Zabner J. Secreted and transmembrane mucins inhibit gene transfer with AAV4 more efficiently than AAV5. The Journal of Biological Chemistry. 277: 23709-13. PMID 11925433 DOI: 10.1074/Jbc.M200292200 |
0.364 |
|
| 2002 |
Wang G, Sinn PL, Zabner J, McCray PB. Gene transfer to airway epithelia using feline immunodeficiency virus-based lentivirus vectors. Methods in Enzymology. 346: 500-14. PMID 11883087 DOI: 10.1016/S0076-6879(02)46073-9 |
0.343 |
|
| 2002 |
Ostedgaard LS, Zabner J, Vermeer DW, Rokhlina T, Karp PH, Stecenko AA, Randak C, Welsh MJ. CFTR with a partially deleted R domain corrects the cystic fibrosis chloride transport defect in human airway epithelia in vitro and in mouse nasal mucosa in vivo. Proceedings of the National Academy of Sciences of the United States of America. 99: 3093-8. PMID 11854474 DOI: 10.1073/Pnas.261714599 |
0.384 |
|
| 2001 |
Yi SM, Harson RE, Zabner J, Welsh MJ. Lectin binding and endocytosis at the apical surface of human airway epithelia. Gene Therapy. 8: 1826-32. PMID 11821935 DOI: 10.1038/Sj.Gt.3301598 |
0.356 |
|
| 2001 |
Yi SM, Lee JH, Graham S, Zabner J, Welsh MJ. Adenovirus calcium phosphate coprecipitates enhance squamous cell carcinoma gene transfer. The Laryngoscope. 111: 1290-6. PMID 11568557 DOI: 10.1097/00005537-200107000-00028 |
0.341 |
|
| 2001 |
Walters RW, van't Hof W, Yi SM, Schroth MK, Zabner J, Crystal RG, Welsh MJ. Apical localization of the coxsackie-adenovirus receptor by glycosyl-phosphatidylinositol modification is sufficient for adenovirus-mediated gene transfer through the apical surface of human airway epithelia. Journal of Virology. 75: 7703-11. PMID 11462042 DOI: 10.1128/Jvi.75.16.7703-7711.2001 |
0.41 |
|
| 2001 |
Walters RW, Yi SM, Keshavjee S, Brown KE, Welsh MJ, Chiorini JA, Zabner J. Binding of adeno-associated virus type 5 to 2,3-linked sialic acid is required for gene transfer. The Journal of Biological Chemistry. 276: 20610-6. PMID 11262413 DOI: 10.1074/Jbc.M101559200 |
0.386 |
|
| 2001 |
Drouin SM, Kildsgaard J, Haviland J, Zabner J, Jia HP, McCray P.B. J, Tack BF, Wetsel RA. Expression of the complement anaphylatoxin C3a and C5a receptors on bronchial epithelial and smooth muscle cells in models of sepsis and asthma Journal of Immunology. 166: 2025-2032. PMID 11160252 DOI: 10.4049/Jimmunol.166.3.2025 |
0.368 |
|
| 2000 |
Jepsen M, Graham S, Karp PH, Zabner J. Effect of topical nasal pharmaceuticals on sodium and chloride transport by human airway epithelia American Journal of Rhinology. 14: 405-409. PMID 11197117 DOI: 10.2500/105065800779954365 |
0.361 |
|
| 2000 |
Zabner J, Seiler MP, Launspach JL, Karp PH, Kearney WR, Look DC, Smith JJ, Welsh MJ. The osmolyte xylitol reduces the salt concentration of airway surface liquid and may enhance bacterial killing. Proceedings of the National Academy of Sciences of the United States of America. 97: 11614-9. PMID 11027360 DOI: 10.1073/Pnas.97.21.11614 |
0.396 |
|
| 2000 |
Toyoda K, Andresen JJ, Zabner J, Faraci FM, Heistad DD. Calcium phosphate precipitates augment adenovirus-mediated gene transfer to blood vessels in vitro and in vivo. Gene Therapy. 7: 1284-91. PMID 10918499 DOI: 10.1038/Sj.Gt.3301214 |
0.344 |
|
| 2000 |
Zabner J, Seiler M, Walters R, Kotin RM, Fulgeras W, Davidson BL, Chiorini JA. Adeno-associated virus type 5 (AAV5) but not AAV2 binds to the apical surfaces of airway epithelia and facilitates gene transfer. Journal of Virology. 74: 3852-8. PMID 10729159 DOI: 10.1128/Jvi.74.8.3852-3858.2000 |
0.431 |
|
| 2000 |
Drapkin PT, O'Riordan CR, Yi SM, Chiorini JA, Cardella J, Zabner J, Welsh MJ. Targeting the urokinase plasminogen activator receptor enhances gene transfer to human airway epithelia. The Journal of Clinical Investigation. 105: 589-96. PMID 10712430 DOI: 10.1172/Jci8858 |
0.38 |
|
| 2000 |
Davidson BL, Stein CS, Heth JA, Martins I, Kotin RM, Derksen TA, Zabner J, Ghodsi A, Chiorini JA. Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system. Proceedings of the National Academy of Sciences of the United States of America. 97: 3428-32. PMID 10688913 DOI: 10.1073/Pnas.050581197 |
0.331 |
|
| 2000 |
Wang G, Zabner J, Deering C, Launspach J, Shao J, Bodner M, Jolly DJ, Davidson BL, McCray PB. Increasing epithelial junction permeability enhances gene transfer to airway epithelia In vivo. American Journal of Respiratory Cell and Molecular Biology. 22: 129-38. PMID 10657931 DOI: 10.1165/Ajrcmb.22.2.3938 |
0.385 |
|
| 1999 |
Wang G, Slepushkin VA, Bodner M, Zabner J, van Es HH, Thomas P, Jolly DJ, Davidson BL, McCray PB. Keratinocyte growth factor induced epithelial proliferation facilitates retroviral-mediated gene transfer to distal lung epithelia in vivo. The Journal of Gene Medicine. 1: 22-30. PMID 10738582 DOI: 10.1002/(Sici)1521-2254(199901/02)1:1<22::Aid-Jgm1>3.3.Co;2-O |
0.398 |
|
| 1999 |
Wang G, Slepushkin V, Zabner J, Keshavjee S, Johnston JC, Sauter SL, Jolly DJ, Dubensky TW, Davidson BL, McCray PB. Feline immunodeficiency virus vectors persistently transduce nondividing airway epithelia and correct the cystic fibrosis defect. The Journal of Clinical Investigation. 104: R55-62. PMID 10587528 DOI: 10.1172/Jci8390 |
0.464 |
|
| 1999 |
Romanczuk H, Galer CE, Zabner J, Barsomian G, Wadsworth SC, O'Riordan CR. Modification of an adenoviral vector with biologically selected peptides: A novel strategy for gene delivery to cells of choice Human Gene Therapy. 10: 2615-2626. PMID 10566889 DOI: 10.1089/10430349950016654 |
0.383 |
|
| 1999 |
Zabner J, Chillon M, Grunst T, Moninger TO, Davidson BL, Gregory R, Armentano D. A chimeric type 2 adenovirus vector with a type 17 fiber enhances gene transfer to human airway epithelia. Journal of Virology. 73: 8689-95. PMID 10482622 DOI: 10.1128/Jvi.73.10.8689-8695.1999 |
0.335 |
|
| 1999 |
Graham SM, Launspach JL, Welsh MJ, Zabner J. Sequential magnetic resonance imaging analysis of the maxillary sinuses: implications for a model of gene therapy in cystic fibrosis. The Journal of Laryngology and Otology. 113: 329-35. PMID 10474667 DOI: 10.1017/S0022215100143907 |
0.368 |
|
| 1999 |
Lee JH, Baker TJ, Mahal LK, Zabner J, Bertozzi CR, Wiemer DF, Welsh MJ. Engineering novel cell surface receptors for virus-mediated gene transfer. The Journal of Biological Chemistry. 274: 21878-84. PMID 10419507 DOI: 10.1074/Jbc.274.31.21878 |
0.351 |
|
| 1999 |
McCray PB, Zabner J, Jia HP, Welsh MJ, Thorne PS. Efficient killing of inhaled bacteria in DeltaF508 mice: role of airway surface liquid composition. The American Journal of Physiology. 277: L183-90. PMID 10409246 DOI: 10.1152/Ajplung.1999.277.1.L183 |
0.397 |
|
| 1999 |
Armentano D, Smith MP, Sookdeo CC, Zabner J, Perricone MA, St. George JA, Wadsworth SC, Gregory RJ. E4ORF3 requirement for achieving long-term transgene expression from the cytomegalovirus promoter in adenovirus vectors Journal of Virology. 73: 7031-7034. PMID 10400804 DOI: 10.1128/Jvi.73.8.7031-7034.1999 |
0.304 |
|
| 1999 |
Welsh MJ, Zabner J. Cationic lipid mediated gene transfer of CFTR: safety of a single administration to the nasal epithelia. Human Gene Therapy. 10: 1559-72. PMID 10395381 DOI: 10.1089/10430349950017897 |
0.411 |
|
| 1999 |
Travis SM, Conway BA, Zabner J, Smith JJ, Anderson NN, Singh PK, Greenberg EP, Welsh MJ. Activity of abundant antimicrobials of the human airway. American Journal of Respiratory Cell and Molecular Biology. 20: 872-9. PMID 10226057 DOI: 10.1165/Ajrcmb.20.5.3572 |
0.411 |
|
| 1999 |
Walters RW, Grunst T, Bergelson JM, Finberg RW, Welsh MJ, Zabner J. Basolateral localization of fiber receptors limits adenovirus infection from the apical surface of airway epithelia. The Journal of Biological Chemistry. 274: 10219-26. PMID 10187807 DOI: 10.1074/Jbc.274.15.10219 |
0.349 |
|
| 1999 |
Lee JH, Zabner J, Welsh MJ. Delivery of an adenovirus vector in a calcium phosphate coprecipitate enhances the therapeutic index of gene transfer to airway epithelia. Human Gene Therapy. 10: 603-13. PMID 10094203 DOI: 10.1089/10430349950018670 |
0.408 |
|
| 1999 |
Chillon M, Bosch A, Zabner J, Law L, Armentano D, Welsh MJ, Davidson BL. Group D adenoviruses infect primary central nervous system cells more efficiently than those from group C. Journal of Virology. 73: 2537-40. PMID 9971839 DOI: 10.1128/Jvi.73.3.2537-2540.1999 |
0.308 |
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| 1999 |
Wang G, Slepushkin VA, Bodner M, Zabner J, Es HHGv, Thomas P, Jolly DJ, Davidson BL, McCray PB. Keratinocyte growth factor induced epithelial proliferation facilitates retroviral–mediated gene transfer to distal lung epithelia in vivo: Retroviral Gene Transfer to Lung Journal of Gene Medicine. 1: 22-30. DOI: 10.1002/(Sici)1521-2254(199901/02)1:1<22::Aid-Jgm1>3.0.Co;2-X |
0.371 |
|
| 1998 |
Zabner J, Smith JJ, Karp PH, Widdicombe JH, Welsh MJ. Loss of CFTR chloride channels alters salt absorption by cystic fibrosis airway epithelia in vitro. Molecular Cell. 2: 397-403. PMID 9774978 DOI: 10.1016/S1097-2765(00)80284-1 |
0.378 |
|
| 1998 |
Factor P, Saldias F, Ridge K, Dumasius V, Zabner J, Jaffe HA, Blanco G, Barnard M, Mercer R, Perrin R, Sznajder JI. Augmentation of lung liquid clearance via adenovirus-mediated transfer of a Na,K-ATPase β1 subunit gene Journal of Clinical Investigation. 102: 1421-1430. PMID 9769335 DOI: 10.1172/Jci3214 |
0.332 |
|
| 1998 |
Fasbender A, Lee JH, Walters RW, Moninger TO, Zabner J, Welsh MJ. Incorporation of adenovirus in calcium phosphate precipitates enhances gene transfer to airway epithelia in vitro and in vivo. The Journal of Clinical Investigation. 102: 184-93. PMID 9649572 DOI: 10.1172/Jci2732 |
0.443 |
|
| 1997 |
Fasbender A, Zabner J, Zeiher BG, Welsh MJ. A low rate of cell proliferation and reduced DNA uptake limit cationic lipid-mediated gene transfer to primary cultures of ciliated human airway epithelia. Gene Therapy. 4: 1173-80. PMID 9425440 DOI: 10.1038/Sj.Gt.3300524 |
0.389 |
|
| 1997 |
Zabner J, Cheng SH, Meeker D, Launspach J, Balfour R, Perricone MA, Morris JE, Marshall J, Fasbender A, Smith AE, Welsh MJ. Comparison of DNA-lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo. The Journal of Clinical Investigation. 100: 1529-37. PMID 9294121 DOI: 10.1172/Jci119676 |
0.326 |
|
| 1997 |
Zabner J, Freimuth P, Puga A, Fabrega A, Welsh MJ. Lack of high affinity fiber receptor activity explains the resistance of ciliated airway epithelia to adenovirus infection. The Journal of Clinical Investigation. 100: 1144-9. PMID 9276731 DOI: 10.1172/Jci119625 |
0.409 |
|
| 1997 |
McCray PB, Wang G, Kline JN, Zabner J, Chada S, Jolly DJ, Chang SM, Davidson BL. Alveolar macrophages inhibit retrovirus-mediated gene transfer to airway epithelia. Human Gene Therapy. 8: 1087-93. PMID 9189766 DOI: 10.1089/Hum.1997.8.9-1087 |
0.435 |
|
| 1997 |
Fasbender A, Zabner J, Chillón M, Moninger TO, Puga AP, Davidson BL, Welsh MJ. Complexes of adenovirus with polycationic polymers and cationic lipids increase the efficiency of gene transfer in vitro and in vivo. The Journal of Biological Chemistry. 272: 6479-89. PMID 9045673 DOI: 10.1074/Jbc.272.10.6479 |
0.389 |
|
| 1997 |
Armentano D, Zabner J, Sacks C, Sookdeo CC, Smith MP, St. George JA, Wadsworth SC, Smith AE, Gregory RJ. Effect of the E4 region on the persistence of transgene expression from adenovirus vectors Journal of Virology. 71: 2408-2416. PMID 9032378 DOI: 10.1128/Jvi.71.3.2408-2416.1997 |
0.346 |
|
| 1997 |
Zabner J. Cationic lipids used in gene transfer Advanced Drug Delivery Reviews. 27: 17-28. DOI: 10.1016/S0169-409X(97)00019-7 |
0.322 |
|
| 1996 |
Fabrega AJ, Fasbender AJ, Struble S, Zabner J. Cationic lipid-mediated transfer of the hIL-10 gene prolongs survival of allogeneic hepatocytes in Nagase analbuminemic rats Transplantation. 62: 1866-1871. PMID 8990378 DOI: 10.1097/00007890-199612270-00032 |
0.304 |
|
| 1996 |
Zabner J, Zeiher BG, Friedman E, Welsh MJ. Adenovirus-mediated gene transfer to ciliated airway epithelia requires prolonged incubation time. Journal of Virology. 70: 6994-7003. PMID 8794344 DOI: 10.1128/Jvi.70.10.6994-7003.1996 |
0.477 |
|
| 1996 |
Goebel EA, Davidson BL, Zabner J, Graham SM, Kern JA. Adenovirus-mediated gene therapy for head and neck squamous cell carcinomas. The Annals of Otology, Rhinology, and Laryngology. 105: 562-7. PMID 8678435 DOI: 10.1177/000348949610500713 |
0.336 |
|
| 1996 |
Zabner J, Ramsey BW, Meeker DP, Aitken ML, Balfour RP, Gibson RL, Launspach J, Moscicki RA, Richards SM, Standaert TA, Williams-Warren J, Wadsworth SC, Smith AE, Welsh MJ. Repeat administration of an adenovirus vector encoding cystic fibrosis transmembrane conductance regulator to the nasal epithelium of patients with cystic fibrosis Journal of Clinical Investigation. 97: 1504-1511. PMID 8617884 DOI: 10.1172/Jci118573 |
0.429 |
|
| 1995 |
Cheng SH, Fang SL, Zabner J, Marshall J, Piraino S, Schiavi SC, Jefferson DM, Welsh MJ, Smith AE. Functional activation of the cystic fibrosis trafficking mutant delta F508-CFTR by overexpression. The American Journal of Physiology. 268: L615-24. PMID 7733303 DOI: 10.1152/Ajplung.1995.268.4.L615 |
0.363 |
|
| 1995 |
Zabner J, Fasbender AJ, Moninger T, Poellinger KA, Welsh MJ. Cellular and molecular barriers to gene transfer by a cationic lipid. The Journal of Biological Chemistry. 270: 18997-9007. PMID 7642560 DOI: 10.1074/Jbc.270.32.18997 |
0.302 |
|
| 1995 |
Fasbender AJ, Zabner J, Welsh MJ. Optimization of cationic lipid-mediated gene transfer to airway epithelia. The American Journal of Physiology. 269: L45-51. PMID 7631813 DOI: 10.1152/Ajplung.1995.269.1.L45 |
0.346 |
|
| 1995 |
Zeiher BG, Eichwald E, Zabner J, Smith JJ, Puga AP, McCray PB, Capecchi MR, Welsh MJ, Thomas KR. A mouse model for the delta F508 allele of cystic fibrosis. The Journal of Clinical Investigation. 96: 2051-64. PMID 7560099 DOI: 10.1172/Jci118253 |
0.311 |
|
| 1995 |
McCray PB, Armstrong K, Zabner J, Miller DW, Koretzky GA, Couture L, Robillard JE, Smith AE, Welsh MJ. Adenoviral-mediated gene transfer to fetal pulmonary epithelia in vitro and in vivo. The Journal of Clinical Investigation. 95: 2620-32. PMID 7539457 DOI: 10.1172/Jci117964 |
0.444 |
|
| 1995 |
Welsh MJ, Zabner J, Graham SM, Smith AE, Moscicki R, Wadsworth S. Adenovirus-mediated gene transfer for cystic fibrosis: Part A. Safety of dose and repeat administration in the nasal epithelium. Part B. Clinical efficacy in the maxillary sinus. Human Gene Therapy. 6: 205-18. PMID 7537540 DOI: 10.1089/Hum.1995.6.2-205 |
0.315 |
|
| 1994 |
Zabner J, Couture LA, Smith AE, Welsh MJ. Correction of cAMP-stimulated fluid secretion in cystic fibrosis airway epithelia: efficiency of adenovirus-mediated gene transfer in vitro. Human Gene Therapy. 5: 585-93. PMID 7519884 DOI: 10.1089/Hum.1994.5.5-585 |
0.434 |
|
| 1994 |
Zabner J, Petersen DM, Puga AP, Graham SM, Couture LA, Keyes LD, Lukason MJ, George JAS, Gregory RJ, Smith AE, Welsh MJ. Safety and efficacy of repetitive adenovirus-mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats Nature Genetics. 6: 75-83. PMID 7511023 DOI: 10.1038/Ng0194-75 |
0.379 |
|
| 1993 |
Zabner J, Couture LA, Gregory RJ, Graham SM, Smith AE, Welsh MJ. Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis Cell. 75: 207-216. PMID 7691415 DOI: 10.1016/0092-8674(93)80063-K |
0.437 |
|
| 1990 |
Zabner J, Angeli LS, Martinez RR, Sánchez de León R. The effects of graded administration of positive end expiratory pressure on the fluid filtration rate in isolated rabbit lungs, using normal lungs, hydrostatic oedema lungs and oleic acid induced oedema Intensive Care Medicine. 16: 89-94. PMID 2185291 DOI: 10.1007/Bf02575300 |
0.307 |
|
| 1989 |
Martinez-Ruiz R, Zabner J, Angeli S, Sanchez de Leon R. Effect of high frequency oscillatory ventilation on fluid filtration rate in isolated perfused rabbit lungs Intensive Care Medicine. 15: 155-159. PMID 2738219 DOI: 10.1007/Bf01058566 |
0.315 |
|
| 1986 |
Sanchez de Leon R, Brajkovich I, Zabner J, Martinez-Ruiz R, Angeli S. Effect of hypercapnia on fluid filtration rate during forward and reverse perfusion of isolated rabbit lungs Critical Care Medicine. 14: 285-287. PMID 3082594 DOI: 10.1097/00003246-198604000-00007 |
0.31 |
|
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