Philip W. Majerus, M.D. - Publications

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
Cell Biology, Molecular Biology, Biochemistry
Website:
https://hematology.im.wustl.edu/people/faculty/Majerus_P/Majerus_P_Bio.html

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Year Citation  Score
2012 Zou J, Zhang C, Marjanovic J, Kisseleva MV, Majerus PW, Wilson MP. Myotubularin-related protein (MTMR) 9 determines the enzymatic activity, substrate specificity, and role in autophagy of MTMR8. Proceedings of the National Academy of Sciences of the United States of America. 109: 9539-44. PMID 22647598 DOI: 10.1073/Pnas.1207021109  0.773
2012 Zhang C, Majerus PW, Wilson MP. Regulation of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) by reversible lysine acetylation. Proceedings of the National Academy of Sciences of the United States of America. 109: 2290-5. PMID 22308441 DOI: 10.1073/Pnas.1119740109  0.411
2012 Zou J, Majerus PW, Wilson DB, Schrade A, Chang SC, Wilson MP. The role of myotubularin-related phosphatases in the control of autophagy and programmed cell death. Advances in Biological Regulation. 52: 282-9. PMID 22056831 DOI: 10.1016/J.Advenzreg.2011.10.001  0.349
2011 Ferron M, Boudiffa M, Arsenault M, Rached M, Pata M, Giroux S, Elfassihi L, Kisseleva M, Majerus PW, Rousseau F, Vacher J. Inositol polyphosphate 4-phosphatase B as a regulator of bone mass in mice and humans. Cell Metabolism. 14: 466-77. PMID 21982707 DOI: 10.1016/J.Cmet.2011.08.013  0.743
2011 Majerus PW. Wandering through the laboratory. The Journal of Biological Chemistry. 286: 4941-5. PMID 21169350 DOI: 10.1074/Jbc.X110.212894  0.343
2011 Marjanovic J, Wilson MP, Zhang C, Zou J, Nicholas P, Majerus PW. The role of inositol polyphosphate 4-phosphatase 1 in platelet function using a weeble mouse model. Advances in Enzyme Regulation. 51: 101-5. PMID 21110994 DOI: 10.1016/J.Advenzreg.2010.11.006  0.341
2010 Majerus PW, Wilson DB, Zhang C, Nicholas PJ, Wilson MP. Expression of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) and its role in neural tube defects. Advances in Enzyme Regulation. 50: 365-72. PMID 19914276 DOI: 10.1016/J.Advenzreg.2009.10.017  0.322
2009 Bielas SL, Silhavy JL, Brancati F, Kisseleva MV, Al-Gazali L, Sztriha L, Bayoumi RA, Zaki MS, Abdel-Aleem A, Rosti RO, Kayserili H, Swistun D, Scott LC, Bertini E, Boltshauser E, ... ... Majerus PW, et al. Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies. Nature Genetics. 41: 1032-6. PMID 19668216 DOI: 10.1038/Ng.423  0.764
2009 Wilson MP, Hugge C, Bielinska M, Nicholas P, Majerus PW, Wilson DB. Neural tube defects in mice with reduced levels of inositol 1,3,4-trisphosphate 5/6-kinase. Proceedings of the National Academy of Sciences of the United States of America. 106: 9831-5. PMID 19482943 DOI: 10.1073/Pnas.0904172106  0.316
2009 Ivetac I, Gurung R, Hakim S, Horan KA, Sheffield DA, Binge LC, Majerus PW, Tiganis T, Mitchell CA. Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4-phosphatase-1. Embo Reports. 10: 487-93. PMID 19325558 DOI: 10.1038/Embor.2009.28  0.372
2009 Zou J, Chang SC, Marjanovic J, Majerus PW. MTMR9 increases MTMR6 enzyme activity, stability, and role in apoptosis. The Journal of Biological Chemistry. 284: 2064-71. PMID 19038970 DOI: 10.1074/Jbc.M804292200  0.38
2009 Majerus PW, York JD. Phosphoinositide phosphatases and disease. Journal of Lipid Research. 50: S249-54. PMID 19001665 DOI: 10.1194/Jlr.R800072-Jlr200  0.613
2008 Majerus PW, Zou J, Marjanovic J, Kisseleva MV, Wilson MP. The role of inositol signaling in the control of apoptosis. Advances in Enzyme Regulation. 48: 10-7. PMID 18486622 DOI: 10.1016/J.Advenzreg.2008.04.001  0.773
2007 Majerus PW. A discrete signaling function for an inositol pyrophosphate. Science's Stke : Signal Transduction Knowledge Environment. 2007: pe72. PMID 18073384 DOI: 10.1126/Stke.4162007Pe72  0.352
2007 Zou J, Marjanovic J, Kisseleva MV, Wilson M, Majerus PW. Type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase regulates stress-induced apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 104: 16834-9. PMID 17940011 DOI: 10.1073/Pnas.0708189104  0.773
2006 Chang SC, Majerus PW. Inositol polyphosphate multikinase regulates inositol 1,4,5,6-tetrakisphosphate. Biochemical and Biophysical Research Communications. 339: 209-16. PMID 16293229 DOI: 10.1016/J.Bbrc.2005.10.201  0.408
2005 Ungewickell A, Hugge C, Kisseleva M, Chang SC, Zou J, Feng Y, Galyov EE, Wilson M, Majerus PW. The identification and characterization of two phosphatidylinositol-4,5-bisphosphate 4-phosphatases. Proceedings of the National Academy of Sciences of the United States of America. 102: 18854-9. PMID 16365287 DOI: 10.1073/Pnas.0509740102  0.773
2005 Verbsky J, Majerus PW. Increased levels of inositol hexakisphosphate (InsP6) protect HEK293 cells from tumor necrosis factor (alpha)- and Fas-induced apoptosis. The Journal of Biological Chemistry. 280: 29263-8. PMID 15967797 DOI: 10.1074/Jbc.M503366200  0.657
2005 Verbsky J, Lavine K, Majerus PW. Disruption of the mouse inositol 1,3,4,5,6-pentakisphosphate 2-kinase gene, associated lethality, and tissue distribution of 2-kinase expression. Proceedings of the National Academy of Sciences of the United States of America. 102: 8448-53. PMID 15939868 DOI: 10.1073/Pnas.0503656102  0.67
2005 Miller GJ, Wilson MP, Majerus PW, Hurley JH. Specificity determinants in inositol polyphosphate synthesis: crystal structure of inositol 1,3,4-trisphosphate 5/6-kinase. Molecular Cell. 18: 201-12. PMID 15837423 DOI: 10.1016/J.Molcel.2005.03.016  0.375
2005 Ivetac I, Munday AD, Kisseleva MV, Zhang XM, Luff S, Tiganis T, Whisstock JC, Rowe T, Majerus PW, Mitchell CA. The type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membrane. Molecular Biology of the Cell. 16: 2218-33. PMID 15716355 DOI: 10.1091/Mbc.E04-09-0799  0.772
2005 Verbsky JW, Chang SC, Wilson MP, Mochizuki Y, Majerus PW. The pathway for the production of inositol hexakisphosphate in human cells. The Journal of Biological Chemistry. 280: 1911-20. PMID 15531582 DOI: 10.1074/Jbc.M411528200  0.697
2004 Ungewickell A, Ward ME, Ungewickell E, Majerus PW. The inositol polyphosphate 5-phosphatase Ocrl associates with endosomes that are partially coated with clathrin. Proceedings of the National Academy of Sciences of the United States of America. 101: 13501-6. PMID 15353600 DOI: 10.1073/Pnas.0405664101  0.756
2004 Rayala HJ, Kendirgi F, Barry DM, Majerus PW, Wente SR. The mRNA export factor human Gle1 interacts with the nuclear pore complex protein Nup155. Molecular & Cellular Proteomics : McP. 3: 145-55. PMID 14645504 DOI: 10.1074/Mcp.M300106-Mcp200  0.325
2003 Sun Y, Mochizuki Y, Majerus PW. Inositol 1,3,4-trisphosphate 5/6-kinase inhibits tumor necrosis factor-induced apoptosis. The Journal of Biological Chemistry. 278: 43645-53. PMID 12925536 DOI: 10.1074/Jbc.M300674200  0.312
2003 Mochizuki Y, Majerus PW. Characterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9. Proceedings of the National Academy of Sciences of the United States of America. 100: 9768-73. PMID 12890864 DOI: 10.1073/Pnas.1333958100  0.405
2003 Nandurkar HH, Layton M, Laporte J, Selan C, Corcoran L, Caldwell KK, Mochizuki Y, Majerus PW, Mitchell CA. Identification of myotubularin as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein, 3-PAP. Proceedings of the National Academy of Sciences of the United States of America. 100: 8660-5. PMID 12847286 DOI: 10.1073/Pnas.1033097100  0.399
2002 Sun Y, Wilson MP, Majerus PW. Inositol 1,3,4-trisphosphate 5/6-kinase associates with the COP9 signalosome by binding to CSN1. The Journal of Biological Chemistry. 277: 45759-64. PMID 12324474 DOI: 10.1074/Jbc.M208709200  0.343
2002 Chang SC, Miller AL, Feng Y, Wente SR, Majerus PW. The human homolog of the rat inositol phosphate multikinase is an inositol 1,3,4,6-tetrakisphosphate 5-kinase. The Journal of Biological Chemistry. 277: 43836-43. PMID 12223481 DOI: 10.1074/Jbc.M206134200  0.412
2002 Verbsky JW, Wilson MP, Kisseleva MV, Majerus PW, Wente SR. The synthesis of inositol hexakisphosphate. Characterization of human inositol 1,3,4,5,6-pentakisphosphate 2-kinase. The Journal of Biological Chemistry. 277: 31857-62. PMID 12084730 DOI: 10.1074/Jbc.M205682200  0.788
2002 Kisseleva MV, Cao L, Majerus PW. Phosphoinositide-specific inositol polyphosphate 5-phosphatase IV inhibits Akt/protein kinase B phosphorylation and leads to apoptotic cell death. The Journal of Biological Chemistry. 277: 6266-72. PMID 11706019 DOI: 10.1074/Jbc.M105969200  0.788
2001 Wilson MP, Sun Y, Cao L, Majerus PW. Inositol 1,3,4-trisphosphate 5/6-kinase is a protein kinase that phosphorylates the transcription factors c-Jun and ATF-2. The Journal of Biological Chemistry. 276: 40998-1004. PMID 11533064 DOI: 10.1074/Jbc.M106605200  0.34
2001 Nandurkar HH, Caldwell KK, Whisstock JC, Layton MJ, Gaudet EA, Norris FA, Majerus PW, Mitchell CA. Characterization of an adapter subunit to a phosphatidylinositol (3)P 3-phosphatase: identification of a myotubularin-related protein lacking catalytic activity. Proceedings of the National Academy of Sciences of the United States of America. 98: 9499-504. PMID 11504939 DOI: 10.1073/Pnas.171306098  0.4
2001 Feng Y, Wente SR, Majerus PW. Overexpression of the inositol phosphatase SopB in human 293 cells stimulates cellular chloride influx and inhibits nuclear mRNA export. Proceedings of the National Academy of Sciences of the United States of America. 98: 875-9. PMID 11158563 DOI: 10.1073/Pnas.98.3.875  0.338
2000 Vyas P, Norris FA, Joseph R, Majerus PW, Orkin SH. Inositol polyphosphate 4-phosphatase type I regulates cell growth downstream of transcription factor GATA-1. Proceedings of the National Academy of Sciences of the United States of America. 97: 13696-701. PMID 11087841 DOI: 10.1073/Pnas.250476397  0.3
2000 Field J, Wilson MP, Mai Z, Majerus PW, Samuelson J. An Entamoeba histolytica inositol 1,3,4-trisphosphate 5/6-kinase has a novel 3-kinase activity. Molecular and Biochemical Parasitology. 108: 119-123. PMID 10802324 DOI: 10.1016/S0166-6851(00)00197-3  0.315
2000 Kisseleva MV, Wilson MP, Majerus PW. The isolation and characterization of a cDNA encoding phospholipid-specific inositol polyphosphate 5-phosphatase. The Journal of Biological Chemistry. 275: 20110-6. PMID 10764818 DOI: 10.1074/Jbc.M910119199  0.783
2000 Kunz J, Wilson MP, Kisseleva M, Hurley JH, Majerus PW, Anderson RA. The activation loop of phosphatidylinositol phosphate kinases determines signaling specificity. Molecular Cell. 5: 1-11. PMID 10678164 DOI: 10.1016/S1097-2765(00)80398-6  0.781
1999 Ungewickell AJ, Majerus PW. Increased levels of plasma lysosomal enzymes in patients with Lowe syndrome. Proceedings of the National Academy of Sciences of the United States of America. 96: 13342-4. PMID 10557322 DOI: 10.1073/Pnas.96.23.13342  0.759
1999 Majerus PW, Kisseleva MV, Norris FA. The role of phosphatases in inositol signaling reactions. The Journal of Biological Chemistry. 274: 10669-72. PMID 10196133 DOI: 10.1074/Jbc.274.16.10669  0.744
1999 Munday AD, Norris FA, Caldwell KK, Brown S, Majerus PW, Mitchell CA. The inositol polyphosphate 4-phosphatase forms a complex with phosphatidylinositol 3-kinase in human platelet cytosol. Proceedings of the National Academy of Sciences of the United States of America. 96: 3640-5. PMID 10097090 DOI: 10.1073/Pnas.96.7.3640  0.407
1998 Norris FA, Wilson MP, Wallis TS, Galyov EE, Majerus PW. SopB, a protein required for virulence of Salmonella dublin, is an inositol phosphate phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 95: 14057-9. PMID 9826652 DOI: 10.1073/Pnas.95.24.14057  0.345
1998 Roach TI, Slater SE, White LS, Zhang X, Majerus PW, Brown EJ, Thomas ML. The protein tyrosine phosphatase SHP-1 regulates integrin-mediated adhesion of macrophages. Current Biology : Cb. 8: 1035-8. PMID 9740804 DOI: 10.1016/S0960-9822(07)00426-5  0.327
1998 Zhang X, Majerus PW. Phosphatidylinositol signalling reactions Seminars in Cell and Developmental Biology. 9: 153-160. PMID 9599410 DOI: 10.1006/Scdb.1997.0220  0.371
1998 Zhang X, Hartz PA, Philip E, Racusen LC, Majerus PW. Cell lines from kidney proximal tubules of a patient with Lowe syndrome lack OCRL inositol polyphosphate 5-phosphatase and accumulate phosphatidylinositol 4,5-bisphosphate. The Journal of Biological Chemistry. 273: 1574-82. PMID 9430698 DOI: 10.1074/Jbc.273.3.1574  0.375
1997 Norris FA, Atkins RC, Majerus PW. The cDNA cloning and characterization of inositol polyphosphate 4-phosphatase type II. Evidence for conserved alternative splicing in the 4-phosphatase family. The Journal of Biological Chemistry. 272: 23859-64. PMID 9295334 DOI: 10.1074/Jbc.272.38.23859  0.391
1997 Zhang X, Loijens JC, Boronenkov IV, Parker GJ, Norris FA, Chen J, Thum O, Prestwich GD, Majerus PW, Anderson RA. Phosphatidylinositol-4-phosphate 5-kinase isozymes catalyze the synthesis of 3-phosphate-containing phosphatidylinositol signaling molecules. The Journal of Biological Chemistry. 272: 17756-61. PMID 9211928 DOI: 10.1074/Jbc.272.28.17756  0.368
1997 Wilson MP, Majerus PW. Characterization of a cDNA encoding Arabidopsis thaliana inositol 1,3,4-trisphosphate 5/6-kinase Biochemical and Biophysical Research Communications. 232: 678-681. PMID 9126335 DOI: 10.1006/Bbrc.1997.6355  0.385
1997 Jefferson AB, Auethavekiat V, Pot DA, Williams LT, Majerus PW. Signaling inositol polyphosphate-5-phosphatase. Characterization of activity and effect of GRB2 association. The Journal of Biological Chemistry. 272: 5983-8. PMID 9038219 DOI: 10.1074/Jbc.272.9.5983  0.427
1997 Auethavekiat V, Abrams CS, Majerus PW. Phosphorylation of platelet pleckstrin activates inositol polyphosphate 5-phosphatase I Journal of Biological Chemistry. 272: 1786-1790. PMID 8999861 DOI: 10.1074/Jbc.272.3.1786  0.413
1996 Liu L, Jefferson AB, Zhang X, Norris FA, Majerus PW, Krystal G. A novel phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase associates with the interleukin-3 receptor. The Journal of Biological Chemistry. 271: 29729-33. PMID 8939907 DOI: 10.1074/Jbc.271.47.29729  0.322
1996 Gu M, Meng K, Majerus PW. The effect of overexpression of the protein tyrosine phosphatase PTPMEG on cell growth and on colony formation in soft agar in COS-7 cells Proceedings of the National Academy of Sciences of the United States of America. 93: 12980-12985. PMID 8917530 DOI: 10.1073/Pnas.93.23.12980  0.34
1996 Osborne MA, Zenner G, Lubinus M, Zhang X, Songyang Z, Cantley LC, Majerus P, Burn P, Kochan JP. The inositol 5'-phosphatase SHIP binds to immunoreceptor signaling motifs and responds to high affinity IgE receptor aggregation Journal of Biological Chemistry. 271: 29271-29278. PMID 8910587 DOI: 10.1074/Jbc.271.46.29271  0.383
1996 Gu M, Majerus PW. The properties of the protein tyrosine phosphatase PTPMEG Journal of Biological Chemistry. 271: 27751-27759. PMID 8910369 DOI: 10.1074/Jbc.271.44.27751  0.434
1996 Kavanaugh WM, Pot DA, Chin SM, Deuter-Reinhard M, Jefferson AB, Norris FA, Masiarz FR, Cousens LS, Majerus PW, Williams LT. Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2. Current Biology : Cb. 6: 438-45. PMID 8723348 DOI: 10.1016/S0960-9822(02)00511-0  0.37
1996 Jefferson AB, Majerus PW. Mutation of the conserved domains of two inositol polyphosphate 5-phosphatases. Biochemistry. 35: 7890-4. PMID 8672490 DOI: 10.1021/Bi9602627  0.4
1996 Wilson MP, Majerus PW. Isolation of inositol 1,3,4-trisphosphate 5/6-kinase, cDNA cloning, and expression of the recombinant enzyme Journal of Biological Chemistry. 271: 11904-11910. PMID 8662638 DOI: 10.1074/Jbc.271.20.11904  0.372
1996 Damen JE, Liu L, Rosten P, Humphries RK, Jefferson AB, Majerus PW, Krystal G. The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 93: 1689-93. PMID 8643691 DOI: 10.1073/Pnas.93.4.1689  0.393
1995 York JD, Ponder JW, Majerus PW. Definition of a metal-dependent/Li(+)-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure. Proceedings of the National Academy of Sciences of the United States of America. 92: 5149-53. PMID 7761465 DOI: 10.1073/Pnas.92.11.5149  0.636
1995 Zhang X, Jefferson AB, Auethavekiat V, Majerus PW. The protein deficient in Lowe syndrome is a phosphatidylinositol-4,5-bisphosphate 5-phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 92: 4853-6. PMID 7761412 DOI: 10.1073/Pnas.92.11.4853  0.42
1995 Jefferson AB, Majerus PW. Properties of type II inositol polyphosphate 5-phosphatase. The Journal of Biological Chemistry. 270: 9370-7. PMID 7721860 DOI: 10.1074/Jbc.270.16.9370  0.37
1995 Norris FA, Auethavekiat V, Majerus PW. The isolation and characterization of cDNA encoding human and rat brain inositol polyphosphate 4-phosphatase. The Journal of Biological Chemistry. 270: 16128-33. PMID 7608176 DOI: 10.1074/Jbc.270.27.16128  0.344
1994 York JD, Chen ZW, Ponder JW, Chauhan AK, Mathews FS, Majerus PW. Crystallization and initial X-ray crystallographic characterization of recombinant bovine inositol polyphosphate 1-phosphatase produced in Spodoptera frugiperda cells. Journal of Molecular Biology. 236: 584-9. PMID 8107142 DOI: 10.1006/Jmbi.1994.1167  0.648
1994 York JD, Ponder JW, Chen ZW, Mathews FS, Majerus PW. Crystal structure of inositol polyphosphate 1-phosphatase at 2.3-A resolution. Biochemistry. 33: 13164-71. PMID 7947723 DOI: 10.1021/Bi00249A002  0.606
1993 Miletich JP, Prescott SM, White R, Majerus PW, Bovill EG. Inherited predisposition to thrombosis Cell. 72: 477-480. PMID 8440014 DOI: 10.1016/0092-8674(93)90063-V  0.541
1993 York JD, Veile RA, Donis-Keller H, Majerus PW. Cloning, heterologous expression, and chromosomal localization of human inositol polyphosphate 1-phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 90: 5833-7. PMID 8390685 DOI: 10.1073/Pnas.90.12.5833  0.635
1992 Gu M, Warshawsky I, Majerus PW. Cloning and expression of a cytosolic megakaryocyte protein-tyrosine- phosphatase with sequence homology to retinaldehyde-binding protein and yeast SEC14p Proceedings of the National Academy of Sciences of the United States of America. 89: 2980-2984. PMID 1557404 DOI: 10.1073/Pnas.89.7.2980  0.4
1992 Majerus PW. Inositol phosphate biochemistry Annual Review of Biochemistry. 61: 225-250. PMID 1323235 DOI: 10.1146/Annurev.Bi.61.070192.001301  0.361
1991 Cunningham TW, Majerus PW. Pathway for the formation of D-3 phosphate containing inositol phospholipids in PDGF stimulated NIH 3T3 fibroblasts. Biochemical and Biophysical Research Communications. 175: 568-76. PMID 1850246 DOI: 10.1016/0006-291X(91)91603-A  0.35
1991 Neuwald AF, York JD, Majerus PW. Diverse proteins homologous to inositol monophosphatase. Febs Letters. 294: 16-8. PMID 1660408 DOI: 10.1016/0014-5793(91)81332-3  0.649
1991 Walsh JP, Caldwell KK, Majerus PW. Formation of phosphatidylinositol 3-phosphate by isomerization from phosphatidylinositol 4-phosphate. Proceedings of the National Academy of Sciences of the United States of America. 88: 9184-7. PMID 1656463 DOI: 10.1073/Pnas.88.20.9184  0.315
1991 Gu MX, York JD, Warshawsky I, Majerus PW. Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1. Proceedings of the National Academy of Sciences of the United States of America. 88: 5867-71. PMID 1648233 DOI: 10.1073/Pnas.88.13.5867  0.662
1990 Majerus PW, Ross TS, Cunningham TW, Caldwell KK, Jefferson AB, Bansal VS. Recent insights in phosphatidylinositol signaling. Cell. 63: 459-65. PMID 2225061 DOI: 10.1016/0092-8674(90)90442-H  0.352
1990 York JD, Majerus PW. Isolation and heterologous expression of a cDNA encoding bovine inositol polyphosphate 1-phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 87: 9548-52. PMID 2175905 DOI: 10.1073/Pnas.87.24.9548  0.657
1990 Mitchell CA, Jefferson AB, Bejeck BE, Brugge JS, Deuel TF, Majerus PW. Thrombin-stimulated immunoprecipitation of phosphatidylinositol 3-kinase from human platelets. Proceedings of the National Academy of Sciences of the United States of America. 87: 9396-400. PMID 2174561 DOI: 10.1073/Pnas.87.23.9396  0.376
1990 Ross TS, Tait JF, Majerus PW. Identity of inositol 1,2-cyclic phosphate 2-phosphohydrolase with lipocortin III Science. 248: 605-607. PMID 2159184 DOI: 10.1126/Science.2159184  0.373
1988 Lips DL, Bross TE, Majerus PW. Isolation of 1-monomethylphosphoinositol 4,5-bisphosphate [a product of methanolysis of inositol 1,2-(cyclic)-4,5-trisphosphate] from Swiss mouse 3T3 cells Proceedings of the National Academy of Sciences of the United States of America. 85: 88-92. PMID 3422429 DOI: 10.1073/Pnas.85.1.88  0.331
1987 Auchus RJ, Kaiser SL, Majerus PW. Synthesis of inositol 1,2-(cyclic)-4,5-trisphosphate Proceedings of the National Academy of Sciences of the United States of America. 84: 1206-1209. PMID 3469663 DOI: 10.1073/Pnas.84.5.1206  0.312
1987 Laposata M, Kaiser SL, Reich EL, Majerus PW. Eicosadiynoic acid: A non-toxic inhibitor of multiple enzymatic steps in the production of icosanoids from arachidonic acid Prostaglandins. 33: 603-614. PMID 3110863 DOI: 10.1016/0090-6980(87)90284-X  0.313
1987 Laposata M, Majerus PW. Measurement of icosanoid precursor uptake and release by intact cells Methods in Enzymology. 350-355. PMID 3110552 DOI: 10.1016/0076-6879(87)41082-3  0.31
1987 Maruyama I, Majerus PW. Protein C inhibits endocytosis of thrombin-thrombomodulin complexes in A549 lung cancer cells and human umbilical vein endothelial cells Blood. 69: 1481-1484. PMID 3032308 DOI: 10.1182/Blood.V69.5.1481.Bloodjournal6951481  0.331
1987 Inhorn RC, Bansal VS, Majerus PW. Pathway for inositol 1,3,4-triphosphate and 1,4-biphosphate metabolism Proceedings of the National Academy of Sciences of the United States of America. 84: 2170-2174. PMID 3031669 DOI: 10.1073/Pnas.84.8.2170  0.357
1987 Wen DZ, Dittman WA, Ye RD, Deaven LL, Majerus PW, Sadler JE. Human thrombomodulin: complete cDNA sequence and chromosome localization of the gene. Biochemistry. 26: 4350-7. PMID 2822087 DOI: 10.1021/Bi00388A025  0.316
1986 Connolly TM, Lawing WJ, Majerus PW. Protein kinase C phosphorylates human platelet inositol trisphosphate 5′-phosphomonoesterase, increasing the phosphatase activity Cell. 46: 951-958. PMID 3019558 DOI: 10.1016/0092-8674(86)90077-2  0.39
1986 Ishii H, Connolly TM, Bross TE, Majerus PW. Inositol cyclic trisphosphate [inositol 1,2-(cyclic)-4,5-trisphosphate] is formed upon thrombin stimulation of human platelets Proceedings of the National Academy of Sciences of the United States of America. 83: 6397-6401. PMID 3018731 DOI: 10.1073/Pnas.83.17.6397  0.326
1985 Auchus RJ, Wilson DB, Covey DF, Majerus PW. The 5-hydroxyl of myo-inositol is essential for uptake into HSDM1C1 mouse fibrosarcoma cells Biochemical and Biophysical Research Communications. 130: 1139-1146. PMID 4026861 DOI: 10.1016/0006-291X(85)91734-6  0.344
1985 Ishii H, Majerus PW. Thrombomodulin is present in human plasma and urine Journal of Clinical Investigation. 76: 2178-2181. PMID 3001144 DOI: 10.1172/Jci112225  0.325
1985 Wilson DB, Bross TE, Sherman WR, Berger RA, Majerus PW. Inositol cyclic phosphates are produced by cleavage of phosphatidylphosphoinositols (polyphosphoinositides) with purified sheep seminal vesicle phospholipase C enzymes. Proceedings of the National Academy of Sciences of the United States of America. 82: 4013-7. PMID 2987959 DOI: 10.1073/Pnas.82.12.4013  0.33
1985 Maruyama I, Salem HH, Ishii H, Majerus PW. Human thrombomodulin is not an efficient inhibitor of the procoagulant activity of thrombin Journal of Clinical Investigation. 75: 987-991. PMID 2984256 DOI: 10.1172/Jci111800  0.343
1984 Maruyama I, Salem HH, Majerus PW. Coagulation Factor V(a) binds to human umbilical vein endothelial cells and accelerates protein C activation Journal of Clinical Investigation. 74: 224-230. PMID 6547457 DOI: 10.1172/Jci111405  0.32
1984 Majerus PW, Neufeld EJ, Wilson DB. Production of phosphoinositide-derived messengers Cell. 37: 701-703. PMID 6331677 DOI: 10.1016/0092-8674(84)90405-7  0.39
1984 Salem HH, Esmon NL, Esmon CT, Majerus PW. Effects of thrombomodulin and coagulation Factor Va-light chain on protein C activation in vitro. Journal of Clinical Investigation. 73: 968-972. PMID 6323539 DOI: 10.1172/Jci111321  0.316
1983 Prescott SM, Majerus PW. Characterization of 1,2-diacylglycerol hydrolysis in human platelets. Demonstration of an arachidonoyl-monoacylglycerol intermediate Journal of Biological Chemistry. 258: 764-769. PMID 6822511  0.583
1983 Salem HH, Broze GJ, Miletich JP, Majerus PW. Human coagulation factor V(a) is a cofactor for the activation of protein C Proceedings of the National Academy of Sciences of the United States of America. 80: 1584-1588. PMID 6572921 DOI: 10.1073/Pnas.80.6.1584  0.303
1983 Bross TE, Prescott SM, Majerus PW. RHC 80267 does not inhibit the diglyceride lipase pathway in intact platelets Biochemical and Biophysical Research Communications. 116: 68-74. PMID 6416255 DOI: 10.1016/0006-291X(83)90381-9  0.594
1983 Neufeld EJ, Wilson DB, Sprecher H, Majerus PW. High affinity esterification of eicosanoid precursor fatty acids by platelets Journal of Clinical Investigation. 72: 214-220. PMID 6308046 DOI: 10.1172/Jci110959  0.305
1983 Majerus PW, Prescott SM, Hofmann SL, Neufeld EJ, Wilson DB. Uptake and release of arachidonate by platelets. Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 11: 45-52. PMID 6221562  0.513
1982 Majerus PW, Prescott SM. Characterization and assay of diacylglycerol lipase from human platelets. Methods in Enzymology. 86: 11-7. PMID 7132746 DOI: 10.1016/0076-6879(82)86162-4  0.613
1982 Wilson DB, Prescott SM, Majerus PW. Discovery of an arachidonoyl coenzyme A synthetase in human platelets Journal of Biological Chemistry. 257: 3510-3515. PMID 7061494  0.575
1982 McEver RP, Baenziger JU, Majerus PW. Isolation and structural characterization of the polypeptide subunits of membrane glycoprotein IIb-IIIa from human platelets Blood. 59: 80-85. PMID 7053767 DOI: 10.1182/Blood.V59.1.80.80  0.564
1982 Laposata M, Prescott SM, Bross TE, Majerus PW. Development and characterization of a tissue culture cell line with essential fatty acid deficiency Proceedings of the National Academy of Sciences of the United States of America. 79: 7654-7658. PMID 6961441 DOI: 10.1073/Pnas.79.24.7654  0.601
1982 Hofmann SL, Prescott SM, Majerus PW. The effects of mepacrine and p-bromophenacyl bromide on arachidonic acid release in human platelets Archives of Biochemistry and Biophysics. 215: 237-244. PMID 6807207 DOI: 10.1016/0003-9861(82)90300-9  0.617
1981 Prescott SM, Majerus PW. The fatty acid composition of phosphatidylinositol from thrombin-stimulated human platelets Journal of Biological Chemistry. 256: 579-582. PMID 7451460  0.566
1981 Broze GJ, Majerus PW. [19] Human factor VII Methods in Enzymology. 80: 228-237. DOI: 10.1016/S0076-6879(81)80021-3  0.316
1980 Bell RL, Baenziger NL, Majerus PW. Bradykinin-stimulated release of arachidonate from phosphatidyl inositol in mouse fibrosarcoma cells. Prostaglandins. 20: 269-74. PMID 7413991 DOI: 10.1016/S0090-6980(80)80045-1  0.343
1980 McEver RP, Baenziger NL, Majerus PW. Isolation and quantitation of the platelet membrane glycoprotein deficient in thrombasthenia using a monoclonal hybridoma antibody. The Journal of Clinical Investigation. 66: 1311-8. PMID 6449521 DOI: 10.1172/Jci109983  0.559
1979 Bell RL, Kennerly DA, Stanford N, Majerus PW. Diglyceride lipase: a pathway for arachidonate release from human platelets. Proceedings of the National Academy of Sciences of the United States of America. 76: 3238-41. PMID 290999 DOI: 10.1073/Pnas.76.7.3238  0.343
1979 Baenziger NL, Becherer PR, Majerus PW. Characterization of prostacyclin synthesis in cultured human arterial smooth muscle cells, venous endothelial cells and skin fibroblasts. Cell. 16: 967-74. PMID 110457 DOI: 10.1016/0092-8674(79)90111-9  0.309
1978 Burch JW, Baenziger NL, Stanford N, Majerus PW. Sensitivity of fatty acid cyclooxygenase from human aorta to acetylation by aspirin. Proceedings of the National Academy of Sciences of the United States of America. 75: 5181-4. PMID 105363 DOI: 10.1073/Pnas.75.10.5181  0.305
1977 Roth GJ, Stanford N, Jacobs JW, Majerus PW. Acetylation of prostaglandin synthetase by aspirin. Purification and properties of the acetylated protein from sheep vesicular gland Biochemistry. 16: 4244-4248. PMID 409429 DOI: 10.1021/Bi00638A018  0.353
1977 Majerus PW, Stanford N. Comparative effects of aspirin and diflunisal on prostaglandin synthetase from human platelets and sheep seminal vesicles British Journal of Clinical Pharmacology. 4. PMID 406909 DOI: 10.1111/J.1365-2125.1977.Tb04509.X  0.336
1977 Stanford N, Roth GJ, Shen TY, Majerus PW. Lack of covalent modification of prostaglandin synthetase (cyclo-oxygenase) by indomethacin Prostaglandins. 13: 669-675. PMID 404672 DOI: 10.1016/0090-6980(77)90237-4  0.319
1977 Minkes M, Stanford N, Chi MM, Roth GJ, Raz A, Needleman P, Majerus PW. Cyclic adenosine 3',5'-monophosphate inhibits the availability of arachidonate to prostaglandin synthetase in human platelet suspensions. The Journal of Clinical Investigation. 59: 449-54. PMID 190267 DOI: 10.1172/Jci108659  0.322
1976 Rome LH, Lands WE, Roth GJ, Majerus PW. Aspirin as a quantitative acetylating reagent for the fatty acid oxygenase that forms prostaglandins. Prostaglandins. 11: 23-30. PMID 176688 DOI: 10.1016/0090-6980(76)90169-6  0.336
1975 Shuman MA, Majerus PW. The perturbation of thrombin binding to human platelets by anions Journal of Clinical Investigation. 56: 945-950. PMID 1159095 DOI: 10.1172/Jci108174  0.3
1975 Roth GJ, Majerus PW. The mechanism of the effect of aspirin on human platelets. I. Acetylation of a particulate fraction protein Journal of Clinical Investigation. 56: 624-632. PMID 1159076 DOI: 10.1172/Jci108132  0.354
1975 Roth GJ, Stanford N, Majerus PW. Acetylation of prostaglandin synthase by aspirin Proceedings of the National Academy of Sciences of the United States of America. 72: 3073-3076. PMID 810797 DOI: 10.1073/Pnas.72.8.3073  0.364
1975 Lyons RM, Stanford N, Majerus PW. Thrombin induced protein phosphorylation in human platelets Journal of Clinical Investigation. 56: 924-936. PMID 169298 DOI: 10.1172/Jci108172  0.402
1972 Brodie GN, Baenziger NL, Chase LR, Majerus PW. The effects of thrombin on adenyl cyclase activity and a membrane protein from human platelets. The Journal of Clinical Investigation. 51: 81-8. PMID 4331802 DOI: 10.1172/Jci106800  0.351
1971 Minnich V, Smith MB, Brauner MJ, Majerus PW. Glutathione biosynthesis in human erythrocytes. I. Identification of the enzymes of glutathione synthesis in hemolysates Journal of Clinical Investigation. 50: 507-513. PMID 5545117 DOI: 10.1172/Jci106519  0.334
1971 Baenziger NL, Brodie GN, Majerus PW. A thrombin-sensitive protein of human platelet membranes. Proceedings of the National Academy of Sciences of the United States of America. 68: 240-3. PMID 5276296 DOI: 10.1073/Pnas.68.1.240  0.328
1971 Majerus PW, Brauner MJ, Smith MB, Minnich V. Glutathione synthesis in human erythrocytes. II. Purification and properties of the enzymes of glutathione biosynthesis Journal of Clinical Investigation. 50: 1637-1643. PMID 5097571 DOI: 10.1172/Jci106652  0.363
1969 Majerus PW, Smith MB, Clamon GH. Lipid metabolism in human platelets. I. Evidence for a complete fatty acid synthesizing system Journal of Clinical Investigation. 48: 156-164. PMID 5765018 DOI: 10.1172/Jci105964  0.369
1969 Lewis N, Majerus PW. Lipid metabolism in human platelets. II. De novo phospholipid synthesis and the effect of thrombin on the pattern of synthesis Journal of Clinical Investigation. 48: 2114-2123. PMID 4309956 DOI: 10.1172/Jci106178  0.355
1969 Alberts AW, Majerus PW, Roy Vagelos P. [8] Malonyl-CoA acyl carrier protein transacylase Methods in Enzymology. 14: 53-56. DOI: 10.1016/S0076-6879(69)14010-0  0.322
1969 Alberts AW, Majerus PW, Roy Vagelos P. [7] Acetyl-CoA acyl carrier protein transacylase Methods in Enzymology. 14: 50-53. DOI: 10.1016/S0076-6879(69)14009-4  0.32
1969 Majerus PW, Alberts AW, Roy Vagelos P. [6] Acyl carrier protein from Escherichia coli Methods in Enzymology. 14: 43-50. DOI: 10.1016/S0076-6879(69)14008-2  0.306
1968 Majerus PW. Acyl carrier protein: Effects of acetylation and tryptic hydrolysis on function in fatty acid synthesis Science. 159: 428-430. DOI: 10.1126/Science.159.3813.428  0.337
1967 Majerus PW, Lastra R. Fatty acid biosynthesis in human leukocytes Journal of Clinical Investigation. 46: 1596-1602. PMID 6061737 DOI: 10.1172/Jci105651  0.315
1967 Majerus PW, Vagelos PR. Fatty acid biosynthesis and the role of the acyl carrier protein. Advances in Lipid Research. 5: 1-33. PMID 4866072  0.549
1966 Rudney H, Stewart PR, Majerus PW, Vagelos PR. The biosynthesis of beta-hydroxy-beta-methylglutaryl coenzyme A in yeast. V. The role of acyl carrier protein. The Journal of Biological Chemistry. 241: 1226-8. PMID 5933879  0.5
1966 Vagelos PR, Majerus PW, Alberts AW, Larrabee AR, Ailhaud GP. Structure and function of the acyl carrier protein. Federation Proceedings. 25: 1485-94. PMID 5332188  0.525
1965 MAJERUS PW, ALBERTS AW, VAGELOS PR. ACYL CARRIER PROTEIN. IV. THE IDENTIFICATION OF 4'-PHOSPHOPANTETHEINE AS THE PROSTHETIC GROUP OF THE ACYL CARRIER PROTEIN. Proceedings of the National Academy of Sciences of the United States of America. 53: 410-7. PMID 14294075  0.534
1965 MAJERUS PW, ALBERTS AW, VAGELOS PR. ACYL CARRIER PROTEIN. 3. AN ENOYL HYDRASE SPECIFIC FOR ACYL CARRIER PROTEIN THIOESTERS. The Journal of Biological Chemistry. 240: 618-21. PMID 14275113  0.544
1965 Majerus PW, Alberts AW, Vagelos PR. Acyl carrier protein. VII. The primary structure of the substrate-binding site. The Journal of Biological Chemistry. 240: 4723-6. PMID 5321310  0.53
1965 Vagelos PR, Alberts AW, Majerus PW. The mechanism of fatty acid biosynthesis and the involvement of an acyl carrier protein. Annals of the New York Academy of Sciences. 131: 177-88. PMID 5216961 DOI: 10.1111/J.1749-6632.1965.Tb34787.X  0.59
1965 Alberts AW, Majerus PW, Vagelos PR. Acyl carrier protein. VI. Purification and properties of β-ketoacyl acyl carrier protein synthetase Biochemistry. 4: 2265-2274. DOI: 10.1021/Bi00887A002  0.576
1964 ALBERTS AW, MAJERUS PW, TALAMO B, VAGELOS PR. ACYL-CARRIER PROTEIN. II. INTERMEDIARY REACTIONS OF FATTY ACID SYNTHESIS. Biochemistry. 3: 1563-71. PMID 14232033 DOI: 10.1021/Bi00898A030  0.584
1964 MAJERUS PW, ALBERTS AW, VAGELOS PR. THE ACYL CARRIER PROTEIN OF FATTY ACID SYNTHESIS: PURIFICATION, PHYSICAL PROPERTIES, AND SUBSTRATE BINDING SITE. Proceedings of the National Academy of Sciences of the United States of America. 51: 1231-8. PMID 14215649  0.544
Low-probability matches (unlikely to be authored by this person)
1976 Shuman MA, Majerus PW. The measurement of thrombin in clotting blood by radioimmunoassay Journal of Clinical Investigation. 58: 1249-1258. PMID 993343 DOI: 10.1172/Jci108579  0.297
1975 Tollefsen DM, Jackson CM, Majerus PW. Binding of the products of prothrombin activation to human platelets Journal of Clinical Investigation. 56: 241-245. PMID 1141438 DOI: 10.1172/Jci108075  0.296
1985 Majerus PW, Wilson DB, Connolly TM, Bross TE, Neufeld EJ. Phosphoinositide turnover provides a link in stimulus—response coupling Trends in Biochemical Sciences. 10: 168-171. DOI: 10.1016/0968-0004(85)90160-4  0.293
1991 Majerus PW, Bansal VS, Lips DL, Ross TA, Mitchell CA, Caldwell KK, Cunningham TW. The phosphatidylinositol pathway of platelets and vascular cells. Annals of the New York Academy of Sciences. 614: 44-50. PMID 2024892 DOI: 10.1111/J.1749-6632.1991.Tb43690.X  0.293
1976 Shuman MA, Tollefsen DM, Majerus PW. The binding of human and bovine thrombin to human platelets Blood. 47: 43-54. PMID 812572 DOI: 10.1182/Blood.V47.1.43.Bloodjournal47143  0.293
1989 Dittman WA, Majerus PW. Sequence of a cDNA for mouse thrombomodulin and comparison of the predicted mouse and human amino acid sequences Nucleic Acids Research. 17: 802. PMID 2536925 DOI: 10.1093/Nar/17.2.802  0.292
1980 Miletich JP, Broze GJ, Majerus PW. The synthesis of sulfated dextran beads for isolation of human plasma coagulation factors II, IX, and X Analytical Biochemistry. 105: 304-310. PMID 6161558 DOI: 10.1016/0003-2697(80)90462-5  0.29
1975 Tollefsen DM, Majerus PW. Inhibition of human platelet aggregation by monovalent antifibrinogen antibody fragments Journal of Clinical Investigation. 55: 1259-1268. PMID 1169259 DOI: 10.1172/Jci108045  0.289
1977 Baenziger NL, Dillender MJ, Majerus PW. Cultured human skin fibroblasts and arterial cells produce a labile platelet-inhibitory prostaglandin. Biochemical and Biophysical Research Communications. 78: 294-301. PMID 907679 DOI: 10.1016/0006-291X(77)91253-0  0.289
1989 Mitchell CA, Connolly TM, Majerus PW. Identification and isolation of a 75-kDa inositol polyphosphate-5-phosphatase from human platelets Journal of Biological Chemistry. 264: 8873-8877. PMID 2542294  0.289
1985 Maruyama I, Bell CE, Majerus PW. Thrombomodulin is found on endothelium of arteries, veins, capillaries, and lymphatics, and on syncytiotrophoblast of human placenta. The Journal of Cell Biology. 101: 363-71. PMID 2991298 DOI: 10.1083/Jcb.101.2.363  0.288
1991 Ross TS, Majerus PW. Inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase: Substrate specificity and regulation of activity by phospholipids, metal ion chelators, and inositol 2-phosphate Journal of Biological Chemistry. 266: 851-856. PMID 1845995  0.288
1974 Feagler JR, Tillack TW, Chaplin DD, Majerus PW. The effects of thrombin on phytohemagglutinin receptor sites in human platelets Journal of Cell Biology. 60: 541-553. PMID 4207395 DOI: 10.1083/Jcb.60.3.541  0.287
1985 Neufeld EJ, Majerus PW, Krueger CM, Saffitz JE. Uptake and subcellular distribution of [3H]arachidonic acid in murine fibrosarcoma cells measured by electron microscope autoradiography Journal of Cell Biology. 101: 573-581. PMID 3926781 DOI: 10.1083/Jcb.101.2.573  0.287
1977 Miletich JP, Jackson CM, Majerus PW. Interaction of coagulation factor X(a) with human platelets Proceedings of the National Academy of Sciences of the United States of America. 74: 4033-4036. PMID 333455 DOI: 10.1073/Pnas.74.9.4033  0.285
1998 Damen JE, Liu L, Ware MD, Ermolaeva M, Majerus PW, Krystal G. Multiple Forms of the SH2-Containing Inositol Phosphatase, SHIP, Are Generated by C-Terminal Truncation Blood. 92: 1199-1205. DOI: 10.1182/Blood.V92.4.1199  0.284
1970 Mohler DN, Majerus PW, Minnich V, Hess CE, Garrick MD. Glutathione synthetase deficiency as a cause of hereditary hemolytic disease. The New England Journal of Medicine. 283: 1253-7. PMID 5476481 DOI: 10.1056/Nejm197012032832304  0.284
1976 Tollefsen DM, Majerus PW. Evidence for a single class of thrombin-binding sites on human platelets Biochemistry. 15: 2144-2149. PMID 819028 DOI: 10.1021/Bi00655A018  0.282
1989 Lips DL, Majerus PW. The discovery of a 3-phosphomonoesterase that hydrolyzes phosphatidylinositol 3-phosphate in NIH 3T3 cells Journal of Biological Chemistry. 264: 19911-19915. PMID 2555336  0.282
1974 Allen RH, Burger RL, Mehlman CS, Majerus PW. Use of vitamin B 12 in affinity chromatography. Methods in Enzymology. 34: 305-14. PMID 4449455 DOI: 10.1016/S0076-6879(74)34031-1  0.282
1982 Kane WH, Mruk JS, Majerus PW. Activation of coagulation Factor V by a platelet protease Journal of Clinical Investigation. 70: 1092-1100. PMID 6752201 DOI: 10.1172/Jci110697  0.282
1986 Ishii H, Salem H, Bell C, Laposata E, Majerus P. Thrombomodulin, an endothelial anticoagulant protein, is absent from the human brain Blood. 67: 362-365. DOI: 10.1182/Blood.V67.2.362.Bloodjournal672362  0.281
1990 Bansal VS, Caldwell KK, Majerus PW. The isolation and characterization of inositol polyphosphate 4-phosphatase. The Journal of Biological Chemistry. 265: 1806-11. PMID 2153145  0.28
1974 Tollefsen DM, Feagler JR, Majerus PW. Induction of the platelet release reaction by phytohemagglutinin Journal of Clinical Investigation. 53: 211-218. PMID 4357613 DOI: 10.1172/Jci107540  0.28
1987 Majerus PW, Connolly TM, Deckmyn H, Ross TS, Bross TE, Ishii H, Bansal VS, Wilson DB. The metabolism of phosphoinositide-derived messenger molecules. Science (New York, N.Y.). 234: 1519-26. PMID 3024320 DOI: 10.1126/Science.3024320  0.28
1989 Dittman WA, Kumada T, Majerus PW. Transcription of thrombomodulin mRNA in mouse hemangioma cells is increased by cycloheximide and thrombin Proceedings of the National Academy of Sciences of the United States of America. 86: 7179-7182. PMID 2550931 DOI: 10.1073/Pnas.86.18.7179  0.279
1978 Burch JW, Stanford N, Majerus PW. Inhibition of platelet prostaglandin synthetase by oral aspirin Journal of Clinical Investigation. 61: 314-319. PMID 413839 DOI: 10.1172/Jci108941  0.278
1981 Miletich JP, Broze GJ, Majerus PW. [18] Purification of human coagulation factors II, IX, and X using sulfated dextran beads Methods in Enzymology. 80: 221-228. DOI: 10.1016/S0076-6879(81)80020-1  0.277
1976 Majerus PW. Why aspirin? Circulation. 54: 357-359. PMID 947566 DOI: 10.1161/01.Cir.54.3.357  0.275
1978 Majerus PW, Miletich JP. Relationships between platelets and coagulation factors in hemostasis Annual Review of Medicine. 29: 41-49. PMID 348040 DOI: 10.1146/Annurev.Me.29.020178.000353  0.273
2010 Fedele CG, Ooms LM, Ho M, Vieusseux J, O'Toole SA, Millar EK, Lopez-Knowles E, Sriratana A, Gurung R, Baglietto L, Giles GG, Bailey CG, Rasko JE, Shields BJ, Price JT, ... Majerus PW, et al. Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers. Proceedings of the National Academy of Sciences of the United States of America. 107: 22231-6. PMID 21127264 DOI: 10.1073/Pnas.1015245107  0.273
1979 Miletich JP, Kane WH, Hofmann SL, Stanford N, Majerus PW. Deficiency of factor Xa-factor Va binding sites on the platelets of a patient with a bleeding disorder. Blood. 54: 1015-1022. DOI: 10.1182/Blood.V54.5.1015.1015  0.272
1974 Baenziger NL, Majerus PW. Isolation of human platelets and platelet surface membranes. Methods in Enzymology. 31: 149-55. PMID 4213668 DOI: 10.1016/0076-6879(74)31015-4  0.272
1986 Salem HH, Esmon NL, Esmon CT, Majerus PW. Complex interaction between factor V(a)-light chain and thrombomodulin in the regulation of protein C activation Annals of the New York Academy of Sciences. 221-227. PMID 3032043 DOI: 10.1111/J.1749-6632.1986.Tb34584.X  0.272
1969 Roy Vagelos P, Alberts AW, Majerus PW. [5] Mechanism of saturated fatty acid biosynthesis in Escherichia coli Methods in Enzymology. 14: 39-43. DOI: 10.1016/S0076-6879(69)14007-0  0.271
1978 Miletich JP, Majerus DW, Majerus PW. Patients with congenital factor V deficiency have decreased factor X(a) binding sites on their platelets Journal of Clinical Investigation. 62: 824-831. PMID 701480 DOI: 10.1172/Jci109194  0.271
1969 Roy Vagelos P, Alberts AW, Majerus PW. [10] β-Ketoacyl acyl carrier protein reductase Methods in Enzymology. 14: 60-63. DOI: 10.1016/S0076-6879(69)14012-4  0.27
1969 Alberts AW, Majerus PW, Roy Vagelos P. [9] β-Ketoacyl acyl carrier protein synthase Methods in Enzymology. 14: 57-60. DOI: 10.1016/S0076-6879(69)14011-2  0.27
1969 Majerus PW, Alberts AW, Roy Vagelos P. [11] β-Hydroxybutyryl acyl carrier protein dehydrase from Escherichia coli Methods in Enzymology. 14: 64-66. DOI: 10.1016/S0076-6879(69)14013-6  0.269
1997 Wilson MP, Majerus PW. A structure-function study of inositol 1,3,4-trisphosphate 5/6-kinase Faseb Journal. 11.  0.267
1988 Kumada T, Dittman WA, Majerus PW. A role for thrombomodulin in the pathogenesis of thrombin-induced thromboembolism in mice Blood. 71: 728-733. PMID 2830928 DOI: 10.1182/Blood.V71.3.728.Bloodjournal713728  0.266
1978 Rotoli B, Miletich JP, Majerus PW. The relation of conductivity to the binding of thrombin to human platelets Thrombosis Research. 13: 1103-1109. PMID 749264 DOI: 10.1016/0049-3848(78)90238-4  0.265
1984 Wilson DB, Salem HH, Mruk JS, Maruyama I, Majerus PW. Biosynthesis of coagulation Factor V by a human hepatocellular carcinoma cell line. Journal of Clinical Investigation. 73: 654-658. PMID 6200498 DOI: 10.1172/Jci111256  0.265
1988 Inhorn RC, Majerus PW. Properties of inositol polyphosphate 1-phosphatase Journal of Biological Chemistry. 263: 14559-14565. PMID 2844776  0.263
1985 Connolly TM, Bross TE, Majerus PW. Isolation of a phosphomonoesterase from human platelets that specifically hydrolyzes the 5-phosphate of inositol 1,4,5,-trisphosphate Journal of Biological Chemistry. 260: 7868-7874. PMID 2989264  0.263
1984 Wilson DB, Bross TE, Hofmann SL, Majerus PW. Hydrolysis of polyphosphoinositides by purified sheep seminal vesicle phospholipase C enzymes Journal of Biological Chemistry. 259: 11718-11724. PMID 6090445  0.263
1996 Majerus PW. Inositols do it all Genes and Development. 10: 1051-1053. PMID 8654921 DOI: 10.1101/Gad.10.9.1051  0.262
1992 Ross TS, Majerus PW. Identification of a phosphodiesterase that converts inositol cyclic 1:2-Phosphate to inositol 2-phosphate Journal of Biological Chemistry. 267: 19924-19928. PMID 1328187  0.261
1985 Wilson DB, Neufeld EJ, Majerus PW. Phosphoinositide interconversion in thrombin-stimulated human platelets Journal of Biological Chemistry. 260: 1046-1051. PMID 2981829  0.259
1990 Bansal VS, Majerus PW. Phosphatidylinositol-derived precursors and signals Annual Review of Cell Biology. 6: 41-67. PMID 2275819 DOI: 10.1146/Annurev.Cb.06.110190.000353  0.258
1994 Norris FA, Majerus PW. Hydrolysis of phosphatidylinositol 3,4-bisphosphate by inositol polyphosphate 4-phosphatase isolated by affinity elution chromatography. The Journal of Biological Chemistry. 269: 8716-20. PMID 8132601  0.255
1987 Inhorn RC, Majerus PW. Inositol polyphosphate 1-phosphatase from calf brain. Purification and inhibition by Li+, Ca2+, and Mn2+ Journal of Biological Chemistry. 262: 15946-15952. PMID 2824473  0.254
1986 Deckmyn H, Tu SM, Majerus PW. Guanine nucleotides stimulate soluble phosphoinositide-specific phospholipase C in the absence of membranes Journal of Biological Chemistry. 261: 16553-16558. PMID 3023354  0.252
1992 Ross TS, Wang FP, Majerus PW. Mammalian cells that express Bacillus cereus phosphatidylinositol-specific phospholipase C have increased levels of inositol cyclic 1:2-phosphate, inositol 1-phosphate, and inositol 2-phosphate Journal of Biological Chemistry. 267: 19919-19923. PMID 1328186  0.249
1984 Salem HH, Maruyama I, Ishii H, Majerus PW. Isolation and characterization of thrombomodulin from human placenta Journal of Biological Chemistry. 259: 12246-12251. PMID 6090461  0.247
1994 York JD, Saffitz JE, Majerus PW. Inositol polyphosphate 1-phosphatase is present in the nucleus and inhibits DNA synthesis. The Journal of Biological Chemistry. 269: 19992-9. PMID 8051083  0.247
1991 Caldwell KK, Lips DL, Bansal VS, Majerus PW. Isolation and characterization of two 3-phosphatases that hydrolyze both phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate. The Journal of Biological Chemistry. 266: 18378-86. PMID 1655747  0.244
1975 Lyons RM, Chaplin H, Tillack TW, Majerus PW. Gamma heavy chain disease: rapid, sustained response to cyclophosphamide and prednisone Blood. 46: 1-9. PMID 1131420 DOI: 10.1182/Blood.V46.1.1.1  0.243
1997 Majerus PW. Tnositol phosphatases and kinases in:"ei,l signaling Faseb Journal. 11.  0.242
1987 Yonezawa S, Maruyama I, Sakae K, Igata A, Majerus PW, Sato E. Thrombomodulin as a marker for vascular tumors. Comparative study with factor VIII and Ulex europaeus I lectin. American Journal of Clinical Pathology. 88: 405-11. PMID 2444096 DOI: 10.1093/Ajcp/88.4.405  0.241
1991 Ross TS, Whiteley B, Graham RA, Majerus PW. Cyclic hydrolase-transfected 3T3 cells have low levels of inositol 1,2-cyclic phosphate and reach confluence at low density Journal of Biological Chemistry. 266: 9086-9092. PMID 1851165  0.239
1986 Connolly TM, Wilson DB, Bross TE, Majerus PW. Isolation and characterization of the inositol cyclic phosphate products of phosphoinositide cleavage by phospholipase C. Metabolism in cell-free extracts Journal of Biological Chemistry. 261: 122-126. PMID 3001044  0.238
1974 Minnich V, Smith ME, Rajanasathit C, Majerus PW. Erythrocyte glutathione synthesis in the neonate Neonatology. 24: 128-133. PMID 4830456 DOI: 10.1159/000240642  0.238
1979 Harter HR, Burch JW, Majerus PW, Stanford N, Delmez JA, Anderson CB, Weerts CA. Prevention of thrombosis in patients on hemodialysis by low-dose aspirin. The New England Journal of Medicine. 301: 577-9. PMID 112475 DOI: 10.1056/Nejm197909133011103  0.237
1985 Laposata M, Reich EL, Majerus PW. Arachidonyl-CoA synthetase. Separation from nonspecific acyl-CoA synthetase and distribution in various cells and tissues Journal of Biological Chemistry. 260: 11016-11020. PMID 4030780  0.231
1972 Allen RH, Majerus PW. Isolation of vitamin B12-binding proteins using affinity chromatography. I. Preparation and properties of vitamin B12-sepharose Journal of Biological Chemistry. 247: 7695-7701. PMID 4636329 DOI: 10.1111/J.1753-4887.1985.Tb06881.X  0.229
2010 Traynor-Kaplan AE, Moody M, Nur M, Gabriel S, Majerus PW, Drumm ML, Langton-Webster B. INO-4995 therapeutic efficacy is enhanced with repeat dosing in cystic fibrosis knockout mice and human epithelia. American Journal of Respiratory Cell and Molecular Biology. 42: 105-12. PMID 19346319 DOI: 10.1165/Rcmb.2008-0380Oc  0.228
1998 Majerus PW. Prostaglandins: Critical roles in pregnancy and colon cancer Current Biology. 8. PMID 9443907 DOI: 10.1016/S0960-9822(98)70053-3  0.226
1988 Dittman WA, Kumada T, Sadler JE, Majerus PW. The structure and function of mouse thrombomodulin. Phorbol myristate acetate stimulates degradation and synthesis of thrombomodulin without affecting mRNA levels in hemangioma cells Journal of Biological Chemistry. 263: 15815-15822. PMID 2844823  0.224
1986 Ross TS, Majerus PW. Isolation of D-myo-inositol 1:2-cyclic phosphate 2-inositolphosphohydrolase from human placenta Journal of Biological Chemistry. 261: 11119-11123. PMID 3015958  0.222
1997 Norris FA, Atkins RC, Majerus PW. Inositol polyphosphate 4-phosphatase is inactivated by calpain-mediated proteolysis in stimulated human platelets. The Journal of Biological Chemistry. 272: 10987-9. PMID 9110986 DOI: 10.1074/jbc.272.17.10987  0.222
1984 Neufeld EJ, Sprecher H, Evans RW, Majerus PW. Fatty acid structural requirements for activity of arachidonyl-CoA synthetase Journal of Lipid Research. 25: 288-293. PMID 6726081  0.211
1971 Keller JW, Majerus PW, Finke EH. An unusual type of spiculated erythrocyte in metastatic liver disease and hemolytic anemia. Report of a case Annals of Internal Medicine. 74: 732-737. PMID 5559438 DOI: 10.7326/0003-4819-74-5-732  0.21
1990 Dittman WA, Majerus PW. Structure and function of thrombomodulin: A natural anticoagulant Blood. 75: 329-336. PMID 2153035 DOI: 10.1182/Blood.V75.2.329.Bloodjournal752329  0.209
1983 Majerus PW. Arachidonate metabolism in vascular disorders Journal of Clinical Investigation. 72: 1521-1525. PMID 6313764 DOI: 10.1172/Jci111110  0.205
1987 Bansal VS, Inhorn RC, Majerus PW. The metabolism of inositol 1,3,4-trisphosphate to inositol 1,3-bisphosphate Journal of Biological Chemistry. 262: 9444-9447. PMID 3036861  0.201
1994 Majerus PW. Bad blood by mutation Nature. 369: 14-15. PMID 8164730 DOI: 10.1038/369014A0  0.201
1983 Salem HH, Broze GJ, Miletich JP, Majerus PW. The light chain of factor V(a) contains the activity of factor V(a) that accelerates protein C activation by thrombin Journal of Biological Chemistry. 258: 8531-8534. PMID 6688078  0.199
1959 GUZE SB, DELONG WB, MAJERUS PW, ROBINS E. Association of clinical psychiatric disease with hyperemesis gravidarum. A three-and-a-half-year follow-up study of 48 patients and 45 controls The New England Journal of Medicine. 261: 1363-1368. PMID 13830524 DOI: 10.1056/Nejm195912312612703  0.196
1995 Norris FA, Ungewickell E, Majerus PW. Inositol hexakisphosphate binds to clathrin assembly protein 3 (AP-3/AP180) and inhibits clathrin cage assembly in vitro. The Journal of Biological Chemistry. 270: 214-7. PMID 7814377 DOI: 10.1074/jbc.270.1.214  0.191
1996 Liu L, Jefferson AB, Majerus PW, Krvstal G. A novel PtdIns-3,4,5-P3 5-phosphatase associates with the IL-3 receptor Experimental Hematology. 24: 1110.  0.191
2004 Insel PA, Kornfeld S, Majerus PW, Marks AR, Marks PA, Relman AS, Scharschmidt BF, Stossel TP, Varki AP, Weiss SJ, Wilson JD. Blasts from the past. The Journal of Clinical Investigation. 114: 1017-33. PMID 15489944 DOI: 10.1172/Jci23321  0.189
2014 Majerus PW. An aspirin a day. Advances in Biological Regulation. 54: 231-41. PMID 24361050 DOI: 10.1016/J.Jbior.2013.09.011  0.189
1975 Roth GJ, Majerus PW. Acetylation of a protein of human platelets by aspirin Clinical Research. 23.  0.188
1985 Maruyama I, Majerus PW. The turnover of thrombin-thrombomodulin complex in cultured human umbilical vein endothelial cells and A549 lung cancer cells. Endocytosis and degradation of thrombin Journal of Biological Chemistry. 260: 15432-15438. PMID 2999116  0.188
1986 Salem H, Maruyama I, Ishii H, Bell CE, Mitchell CA, Thompson EA, Majerus PW. The anticoagulant properties of thrombomodulin Medical Journal of Australia. 144. DOI: 10.5694/J.1326-5377.1986.Tb112380.X  0.186
1973 Jacobs RA, Majerus PW. The regulation of fatty acid synthesis in human skin fibroblasts. Inhibition of fatty acid synthesis by free fatty acids Journal of Biological Chemistry. 248: 8392-8401. PMID 4148669  0.184
1960 MAJERUS PW, GUZE SB, DELONG WB, ROBINS E. Psychologic factors and psychiatric disease in hyperemesis gravidarum: a follow-up study of 69 vomiters and 66 controls The American Journal of Psychiatry. 117: 421-428. PMID 13765540 DOI: 10.1176/Ajp.117.5.421  0.184
1972 Johnson FL, Lerner KG, Siegel M, Feagler JR, Majerus PW, Hartmann JR, Thomas ED. Association Of Androgenic-Anabolic Steroid Therapy With Development Of Hepatocellular Carcinoma The Lancet. 300: 1273-1276. PMID 4117807 DOI: 10.1016/S0140-6736(72)92649-9  0.183
1972 Baenziger NL, Brodie GN, Majerus PW. Isolation and properties of a thrombin-sensitive protein of human platelets. The Journal of Biological Chemistry. 247: 2723-31. PMID 4260214  0.182
1967 Majerus PW. Acyl carrier protein. Structural requirements for function in fatty acid biosynthesis Journal of Biological Chemistry. 242: 2325-2332. PMID 5338128  0.181
1982 Majerus PW. Fraud in medical research. Presidential address delivered before the 74th annual meeting of the American Society for Clinical Investigation, Washington, DC, 8 May 1982 Journal of Clinical Investigation. 70: 213-217. PMID 7085885 DOI: 10.1172/Jci110597  0.178
1984 Neufeld EJ, Bross TE, Majerus PW. A mutant HSDM1C1 fibrosarcoma line selected for eicosanoid precursor uptake lacks arachidonate-specific acyl-CoA synthetase Journal of Biological Chemistry. 259: 1986-1992. PMID 6420417  0.178
1980 Majerus PW. Chemical messengers of the inflammatory process. Handbook of inflammation, volume 1 Cell. 21: 590-591. DOI: 10.1016/0092-8674(80)90498-5  0.178
1994 York JD, Majerus PW. Nuclear phosphatidylinositols decrease during S-phase of the cell cycle in HeLa cells. The Journal of Biological Chemistry. 269: 7847-50. PMID 8132500  0.165
1983 Neufeld EJ, Majerus PW. Arachidonate release and phosphatidic acid turnover in stimulated human platelets Journal of Biological Chemistry. 258: 2461-2467. PMID 6401733  0.165
1975 Shuman MA, Majerus PW. The physiologic significance of the thrombin receptor on platelets Clinical Research. 23.  0.162
1986 Wilson DB, Majerus PW. Reply from Wilson and Majerus Trends in Biochemical Sciences. 11: 68. DOI: 10.1016/0968-0004(86)90262-8  0.16
1982 Hofmann SL, Majerus PW. Identification and properties of two distinct phosphatidylinositol-specific phospholipase C enzymes from sheep seminal vesicular glands Journal of Biological Chemistry. 257: 6461-6469. PMID 7076678  0.157
1980 Bell RL, Stanford N, Kennerly DA, Majerus PW. Diglyceride lipase: a pathway for arachidonate release from human platelets. Advances in Prostaglandin and Thromboxane Research. 6: 219-24. PMID 7386261  0.156
1980 Bell RL, Majerus PW. Thrombin-induced hydrolysis of phosphatidylinositol in human platelets. The Journal of Biological Chemistry. 255: 1790-2. PMID 6766454  0.156
1980 Kane WH, Lindhout MJ, Jackson CM, Majerus PW. Factor V(a)-dependent binding of factor X(a) to human platelets Journal of Biological Chemistry. 255: 1170-1174. PMID 7356655  0.154
1974 Tollefsen DM, Feagler JR, Majerus PW. The binding of thrombin to the surface of human platelets Journal of Biological Chemistry. 249: 2646-2651. PMID 4856653  0.153
1982 Majerus PW, Prescott SM. [2] Characterization and assay of diacylglycerol lipase from human platelets Methods in Enzymology. 86: 11-17. DOI: 10.1016/0076-6879(82)86162-4  0.147
1980 Broze GJ, Majerus PW. Purification and properties of human coagulation factor VII Journal of Biological Chemistry. 255: 1242-1247. PMID 7354023  0.146
1969 Majerus PW, Kilburn E. Acetyl coenzyme A carboxylase. The roles of synthesis and degradation in regulation of enzyme levels in rat liver Journal of Biological Chemistry. 244: 6254-6262. PMID 4981792  0.144
1998 Damen JE, Liu L, Ware MD, Ermolaeva M, Majerus PW, Krystal G. Multiple Forms of the SH2-Containing Inositol Phosphatase, SHIP, Are Generated by C-Terminal Truncation Blood. 92: 1199-1205. DOI: 10.1182/blood.V92.4.1199  0.144
1979 Burch JW, Majerus PW. The role of prostaglandins in platelet function Seminars in Hematology. 16: 196-207. PMID 113883  0.141
1986 Ishii H, Salem H, Bell C, Laposata E, Majerus P. Thrombomodulin, an endothelial anticoagulant protein, is absent from the human brain Blood. 67: 362-365. DOI: 10.1182/blood.V67.2.362.bloodjournal672362  0.138
1981 Kane WH, Majerus PW. Purification and characterization of human coagulation factor V Journal of Biological Chemistry. 256: 1002-1007. PMID 7451453  0.138
1972 Allen RH, Majerus PW. Isolation of vitamin B12-binding proteins using affinity chromatography. 3. Purification and properties of human plasma transcobalamin II Journal of Biological Chemistry. 247: 7709-7717. PMID 4636330  0.134
1974 Baenziger NL, Majerus PW. [12] Isolation of human platelets and platelet surface membranes Methods in Enzymology. 31: 149-155. DOI: 10.1016/0076-6879(74)31015-4  0.128
1972 Majerus PW, Brodie GN. The binding of phytohemagglutinins to human platelet plasma membranes Journal of Biological Chemistry. 247: 4253-4257. PMID 4113818  0.126
1973 Jacobs RA, Sly WS, Majerus PW. The regulation of fatty acid biosynthesis in human skin fibroblasts Journal of Biological Chemistry. 248: 1268-1276. PMID 4734469  0.125
1978 Miletich JP, Jackson CM, Majerus PW. Properties of the factor X(a) binding site on human platelets Journal of Biological Chemistry. 253: 6908-6916. PMID 690132  0.123
1982 Kane WH, Majerus PW. The interaction of human coagulation factor V(a) with platelets Journal of Biological Chemistry. 257: 3963-3969. PMID 7061520  0.121
1972 Allen RH, Majerus PW. Isolation of vitamin B12-binding proteins using affinity chromatography. II. Purification and properties of a human granulocyte vitamine B12-binding protein Journal of Biological Chemistry. 247: 7702-7708. PMID 4508457  0.12
1971 Majerus PW, Baenziger NL, Brodie GN. Lipid metabolism in human platelets. Series Haematologica (1968). 4: 59-74. PMID 5117886  0.113
1968 Majerus PW, Jacobs R, Smith MB, Morris HP. The regulation of fatty acid biosynthesis in rat hepatomas Journal of Biological Chemistry. 243: 3588-3595. PMID 4298070  0.103
1970 Jacobs R, Kilburn E, Majerus PW. Acetyl coenzyme A carboxylase. The effects of biotin deficiency on enzyme in rat liver and adipose tissue Journal of Biological Chemistry. 245: 6462-6467. PMID 5484820  0.103
1977 Burch JW, Stanford N, Majerus PW. Inhibition of platelet cyclo oxygenase by oral aspirin Clinical Research. 25.  0.1
1982 Hofmann SL, Majerus PW. Modulation of phosphatidylinositol-specific phospholipase C activity by phospholipid interactions, diglycerides, and calcium ions Journal of Biological Chemistry. 257: 14359-14364. PMID 7142213  0.087
1991 Majerus PW. The George M. Kober Lecture: molecular mechanisms of intracellular signal transduction Transactions of the Association of American Physicians. 104. PMID 1668985  0.084
1979 Rotoli B, Majerus PW. Plasma antithrombins and thrombin binding to platelets in plasma Haematologica. 64: 537-551. PMID 92440  0.084
1982 Prescott SM, Majerus PW. Platelet and vascular effects of aspirin Primary Cardiology. 8: 58-68.  0.079
1986 Majerus PW. The production of phosphoinositide-derived messenger molecules Harvey Lectures. 82: 145-155. PMID 2834305  0.057
2011 Majerus PW. Wandering through the laboratory (The Journal of Biological Chemistry (2011) 286 (4941-4945) DOI: 10.1074/jbc.A110.212894) Journal of Biological Chemistry. 286: 17398.  0.025
1978 Majerus PW. Journals as filters or sponges New England Journal of Medicine. 299: 1139. PMID 703804  0.01
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