Robert Tjian - Publications

Biochemistry University of California, Berkeley, Berkeley, CA, United States 
Mechanisms of eukaryotic transcription

321 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ferrie JJ, Karr JP, Graham TGW, Dailey GM, Zhang G, Tjian R, Darzacq X. p300 Is an Obligate Integrator of Combinatorial Transcription Factor Inputs. Biorxiv : the Preprint Server For Biology. PMID 37292840 DOI: 10.1101/2023.05.18.541220  0.715
2023 Dahal L, Walther N, Tjian R, Darzacq X, Graham TGW. Single-molecule tracking (SMT): a window into live-cell transcription biochemistry. Biochemical Society Transactions. PMID 36876879 DOI: 10.1042/BST20221242  0.607
2022 Hsieh TS, Cattoglio C, Slobodyanyuk E, Hansen AS, Darzacq X, Tjian R. Enhancer-promoter interactions and transcription are largely maintained upon acute loss of CTCF, cohesin, WAPL or YY1. Nature Genetics. 54: 1919-1932. PMID 36471071 DOI: 10.1038/s41588-022-01223-8  0.836
2022 Chen Y, Cattoglio C, Dailey GM, Zhu Q, Tjian R, Darzacq X. Mechanisms governing target search and binding dynamics of hypoxia-inducible factors. Elife. 11. PMID 36322456 DOI: 10.7554/eLife.75064  0.691
2022 Ferrie JJ, Karr JP, Tjian R, Darzacq X. "Structure"-function relationships in eukaryotic transcription factors: The role of intrinsically disordered regions in gene regulation. Molecular Cell. 82: 3970-3984. PMID 36265487 DOI: 10.1016/j.molcel.2022.09.021  0.692
2022 Graham TGW, Ferrie JJ, Dailey GM, Tjian R, Darzacq X. Detecting molecular interactions in live-cell single-molecule imaging with proximity-assisted photoactivation (PAPA). Elife. 11. PMID 35976226 DOI: 10.7554/eLife.76870  0.579
2022 Chong S, Graham TGW, Dugast-Darzacq C, Dailey GM, Darzacq X, Tjian R. Tuning levels of low-complexity domain interactions to modulate endogenous oncogenic transcription. Molecular Cell. PMID 35483357 DOI: 10.1016/j.molcel.2022.04.007  0.758
2022 Xie L, Dong P, Qi Y, Hsieh TS, English BP, Jung S, Chen X, De Marzio M, Casellas R, Chang HY, Zhang B, Tjian R, Liu Z. BRD2 compartmentalizes the accessible genome. Nature Genetics. 54: 481-491. PMID 35410381 DOI: 10.1038/s41588-022-01044-9  0.827
2022 Karr JP, Ferrie JJ, Tjian R, Darzacq X. The transcription factor activity gradient (TAG) model: contemplating a contact-independent mechanism for enhancer-promoter communication. Genes & Development. 36: 7-16. PMID 34969825 DOI: 10.1101/gad.349160.121  0.641
2022 Darzacq X, Tjian R. Weak multivalent biomolecular interactions: a strength versus numbers tug of war with implications for phase partitioning. Rna (New York, N.Y.). 28: 48-51. PMID 34772790 DOI: 10.1261/rna.079004.121  0.623
2021 Hung KL, Yost KE, Xie L, Shi Q, Helmsauer K, Luebeck J, Schöpflin R, Lange JT, Chamorro González R, Weiser NE, Chen C, Valieva ME, Wong IT, Wu S, Dehkordi SR, ... ... Tjian R, et al. ecDNA hubs drive cooperative intermolecular oncogene expression. Nature. PMID 34819668 DOI: 10.1038/s41586-021-04116-8  0.508
2021 Herbst DA, Esbin MN, Louder RK, Dugast-Darzacq C, Dailey GM, Fang Q, Darzacq X, Tjian R, Nogales E. Structure of the human SAGA coactivator complex. Nature Structural & Molecular Biology. PMID 34811519 DOI: 10.1038/s41594-021-00682-7  0.607
2021 Graham TGW, Dugast-Darzacq C, Dailey GM, Darzacq X, Tjian R. Simple, Inexpensive RNA Isolation and One-Step RT-qPCR Methods for SARS-CoV-2 Detection and General Use. Current Protocols. 1: e130. PMID 33905620 DOI: 10.1002/cpz1.130  0.576
2021 Narlikar GJ, Myong S, Larson D, Maeshima K, Francis N, Rippe K, Sabari B, Strader L, Tjian R. Is transcriptional regulation just going through a phase? Molecular Cell. 81: 1579-1585. PMID 33861943 DOI: 10.1016/j.molcel.2021.03.046  0.302
2021 Graham TGW, Dugast-Darzacq C, Dailey GM, Nguyenla XH, Van Dis E, Esbin MN, Abidi A, Stanley SA, Darzacq X, Tjian R. Open-source RNA extraction and RT-qPCR methods for SARS-CoV-2 detection. Plos One. 16: e0246647. PMID 33534838 DOI: 10.1371/journal.pone.0246647  0.547
2020 Cattoglio C, Darzacq X, Tjian R, Hansen AS. Estimating Cellular Abundances of Halo-tagged Proteins in Live Mammalian Cells by Flow Cytometry. Bio-Protocol. 10: e3527. PMID 33654751 DOI: 10.21769/BioProtoc.3527  0.566
2020 Cattoglio C, Pustova I, Darzacq X, Tjian R, Hansen AS. Assessing Self-interaction of Mammalian Nuclear Proteins by Co-immunoprecipitation. Bio-Protocol. 10: e3526. PMID 33654750 DOI: 10.21769/BioProtoc.3526  0.586
2020 Park SR, Hauver J, Zhang Y, Revyakin A, Coleman RA, Tjian R, Chu S, Pertsinidis A. A Single-Molecule Surface-Based Platform to Detect the Assembly and Function of the Human RNA Polymerase II Transcription Machinery. Structure (London, England : 1993). PMID 32763141 DOI: 10.1016/J.Str.2020.07.009  0.387
2020 Esbin MN, Whitney ON, Chong S, Maurer A, Darzacq X, Tjian R. Overcoming the bottleneck to widespread testing: A rapid review of nucleic acid testing approaches for COVID-19 detection. Rna (New York, N.Y.). PMID 32358057 DOI: 10.1261/Rna.076232.120  0.647
2020 Esbin MN, Tjian R. Distinct Handoff Mechanism for TBP-TATA DNA Engagement Revealed by SAGA Structures. Biochemistry. 59: 1647-1649. PMID 32302472 DOI: 10.1021/Acs.Biochem.0C00190  0.311
2020 Hsieh TS, Cattoglio C, Slobodyanyuk E, Hansen AS, Rando OJ, Tjian R, Darzacq X. Resolving the 3D Landscape of Transcription-Linked Mammalian Chromatin Folding. Molecular Cell. PMID 32213323 DOI: 10.1016/J.Molcel.2020.03.002  0.827
2020 Xie L, Dong P, Chen X, Hsieh TS, Banala S, De Marzio M, English BP, Qi Y, Jung SK, Kieffer-Kwon KR, Legant WR, Hansen AS, Schulmann A, Casellas R, Zhang B, ... ... Tjian R, et al. 3D ATAC-PALM: super-resolution imaging of the accessible genome. Nature Methods. PMID 32203384 DOI: 10.1038/S41592-020-0775-2  0.794
2019 Piccolo FM, Liu Z, Dong P, Hsu CL, Stoyanova EI, Rao A, Tjian R, Heintz N. MeCP2 nuclear dynamics in live neurons results from low and high affinity chromatin interactions. Elife. 8. PMID 31868585 DOI: 10.7554/Elife.51449  0.47
2019 Wan L, Chong S, Xuan F, Liang A, Cui X, Gates L, Carroll TS, Li Y, Feng L, Chen G, Wang SP, Ortiz MV, Daley SK, Wang X, Xuan H, ... ... Tjian R, et al. Impaired cell fate through gain-of-function mutations in a chromatin reader. Nature. PMID 31853060 DOI: 10.1038/S41586-019-1842-7  0.623
2019 Hansen AS, Amitai A, Cattoglio C, Tjian R, Darzacq X. Guided nuclear exploration increases CTCF target search efficiency. Nature Chemical Biology. PMID 31792445 DOI: 10.1038/S41589-019-0422-3  0.663
2019 McSwiggen DT, Mir M, Darzacq X, Tjian R. Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences. Genes & Development. PMID 31594803 DOI: 10.1101/Gad.331520.119  0.762
2019 Hansen AS, Hsieh TS, Cattoglio C, Pustova I, Saldaña-Meyer R, Reinberg D, Darzacq X, Tjian R. Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF. Molecular Cell. PMID 31522987 DOI: 10.1016/J.Molcel.2019.07.039  0.82
2019 Cattoglio C, Pustova I, Walther N, Ho JJ, Hantsche-Grininger M, Inouye CJ, Hossain MJ, Dailey GM, Ellenberg J, Darzacq X, Tjian R, Hansen AS. Determining cellular CTCF and cohesin abundances to constrain 3D genome models. Elife. 8. PMID 31205001 DOI: 10.7554/Elife.40164  0.657
2019 McSwiggen DT, Hansen AS, Teves SS, Marie-Nelly H, Hao Y, Heckert AB, Umemoto KK, Dugast-Darzacq C, Tjian R, Darzacq X. Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation. Elife. 8. PMID 31038454 DOI: 10.7554/Elife.47098  0.829
2019 Hollerer I, Barker JC, Jorgensen V, Tresenrider A, Dugast-Darzacq C, Chan LY, Darzacq X, Tjian R, Ünal E, Brar GA. Evidence for an Integrated Gene Repression Mechanism Based on mRNA Isoform Toggling in Human Cells. G3 (Bethesda, Md.). PMID 30723103 DOI: 10.1534/G3.118.200802  0.721
2019 McSwiggen DT, Hansen AS, Teves SS, Marie-Nelly H, Hao Y, Heckert AB, Umemoto KK, Dugast-Darzacq C, Tjian R, Darzacq X. Author response: Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation Elife. DOI: 10.7554/Elife.47098.034  0.727
2018 Teves SS, An L, Bhargava-Shah A, Xie L, Darzacq X, Tjian R. A stable mode of bookmarking by TBP recruits RNA Polymerase II to mitotic chromosomes. Elife. 7. PMID 29939130 DOI: 10.7554/Elife.35621  0.854
2018 Chong S, Dugast-Darzacq C, Liu Z, Dong P, Dailey GM, Cattoglio C, Heckert A, Banala S, Lavis L, Darzacq X, Tjian R. Imaging dynamic and selective low-complexity domain interactions that control gene transcription. Science (New York, N.Y.). PMID 29930090 DOI: 10.1126/Science.Aar2555  0.802
2018 Tsui C, Inouye C, Levy M, Lu A, Florens L, Washburn MP, Tjian R. dCas9-targeted locus-specific protein isolation method identifies histone gene regulators. Proceedings of the National Academy of Sciences of the United States of America. PMID 29507191 DOI: 10.1073/Pnas.1718844115  0.477
2018 Liu Z, Tjian R. Visualizing transcription factor dynamics in living cells. The Journal of Cell Biology. PMID 29378780 DOI: 10.1083/Jcb.201710038  0.533
2018 Hansen AS, Woringer M, Grimm JB, Lavis LD, Tjian R, Darzacq X. Robust model-based analysis of single-particle tracking experiments with Spot-On. Elife. 7. PMID 29300163 DOI: 10.7554/Elife.33125  0.595
2018 Teves SS, An L, Bhargava-Shah A, Xie L, Darzacq X, Tjian R. Author response: A stable mode of bookmarking by TBP recruits RNA polymerase II to mitotic chromosomes Elife. DOI: 10.7554/Elife.35621.035  0.729
2017 Knight S, Tjian R, Doudna J. GENOMES IN FOCUS: DEVELOPMENT AND APPLICATIONS OF CRISPR-CAS9 IMAGING TECHNOLOGIES. Angewandte Chemie (International Ed. in English). PMID 29080263 DOI: 10.1002/Anie.201709201  0.344
2017 Hansen AS, Cattoglio C, Darzacq X, Tjian R. Recent evidence that TADs and chromatin loops are dynamic structures. Nucleus (Austin, Tex.). 0. PMID 29077530 DOI: 10.1080/19491034.2017.1389365  0.664
2017 Xie L, Torigoe SE, Xiao J, Mai DH, Li L, Davis FP, Dong P, Marie-Nelly H, Grimm J, Lavis L, Darzacq X, Cattoglio C, Liu Z, Tjian R. A dynamic interplay of enhancer elements regulates Klf4 expression in naïve pluripotency. Genes & Development. 31: 1795-1808. PMID 28982762 DOI: 10.1101/Gad.303321.117  0.819
2017 Zhang Z, Tjian R. Measuring dynamics of eukaryotic transcription initiation: challenges, insights and opportunities. Transcription. 0. PMID 28920762 DOI: 10.1080/21541264.2017.1363017  0.344
2017 Greider C, Hopkins N, Steitz J, Amon A, Asai D, Barres B, Bass B, Bassler B, Birgeneau R, Bjorkman P, Botchan M, Brugge J, Cech T, Colwell R, Craig N, ... ... Tjian R, et al. Not just Salk. Science (New York, N.Y.). 357: 1105-1106. PMID 28912235 DOI: 10.1126/Science.Aao6221  0.713
2017 Ho JJ, Cattoglio C, McSwiggen DT, Tjian R, Fong YW. Regulation of DNA demethylation by the XPC DNA repair complex in somatic and pluripotent stem cells. Genes & Development. 31: 830-844. PMID 28512237 DOI: 10.1101/Gad.295741.116  0.316
2017 Hansen AS, Pustova I, Cattoglio C, Tjian R, Darzacq X. CTCF and cohesin regulate chromatin loop stability with distinct dynamics. Elife. 6. PMID 28467304 DOI: 10.7554/eLife.25776  0.647
2017 Timblin GA, Xie L, Tjian R, Schlissel MS. Dual mechanism of Rag gene repression by c-Myb during pre-B cell proliferation. Molecular and Cellular Biology. PMID 28373291 DOI: 10.1128/Mcb.00437-16  0.813
2017 Hansen AS, Pustova I, Cattoglio C, Tjian R, Darzacq X. Author response: CTCF and cohesin regulate chromatin loop stability with distinct dynamics Elife. DOI: 10.7554/Elife.25776.038  0.334
2016 Teves SS, An L, Hansen AS, Xie L, Darzacq X, Tjian R. A dynamic mode of mitotic bookmarking by transcription factors. Elife. 5. PMID 27855781 DOI: 10.7554/Elife.22280  0.835
2016 Zhang Z, English BP, Grimm JB, Kazane SA, Hu W, Tsai A, Inouye C, You C, Piehler J, Schultz PG, Lavis LD, Revyakin A, Tjian R. Rapid dynamics of general transcription factor TFIIB binding during preinitiation complex assembly revealed by single-molecule analysis. Genes & Development. 30: 2106-2118. PMID 27798851 DOI: 10.1101/Gad.285395.116  0.56
2016 East-Seletsky A, O'Connell MR, Knight SC, Burstein D, Cate JH, Tjian R, Doudna JA. Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection. Nature. PMID 27669025 DOI: 10.1038/Nature19802  0.339
2016 Li L, Liu H, Dong P, Li D, Legant WR, Grimm JB, Lavis LD, Betzig E, Tjian R, Liu Z. Real-time imaging of Huntingtin aggregates diverting target search and gene transcription. Elife. 5. PMID 27484239 DOI: 10.7554/Elife.17056  0.528
2016 He Y, Yan C, Fang J, Inouye C, Tjian R, Ivanov I, Nogales E. Near-atomic resolution visualization of human transcription promoter opening. Nature. 533: 359-65. PMID 27193682 DOI: 10.1107/S0108767317097483  0.396
2016 Kong NR, Davis M, Chai L, Winoto A, Tjian R. MEF2C and EBF1 Co-regulate B Cell-Specific Transcription. Plos Genetics. 12: e1005845. PMID 26900922 DOI: 10.1371/Journal.Pgen.1005845  0.475
2016 Coleman RA, Liu Z, Darzacq X, Tjian R, Singer RH, Lionnet T. Imaging Transcription: Past, Present, and Future. Cold Spring Harbor Symposia On Quantitative Biology. PMID 26763984 DOI: 10.1101/Sqb.2015.80.027201  0.733
2016 Teves SS, An L, Hansen AS, Xie L, Darzacq X, Tjian R. Author response: A dynamic mode of mitotic bookmarking by transcription factors Elife. DOI: 10.7554/Elife.22280.029  0.758
2016 Li L, Liu H, Dong P, Li D, Legant WR, Grimm JB, Lavis LD, Betzig E, Tjian R, Liu Z. Author response: Real-time imaging of Huntingtin aggregates diverting target search and gene transcription Elife. DOI: 10.7554/Elife.17056.034  0.476
2016 Horlbeck MA, Witkowsky LB, Guglielmi B, Replogle JM, Gilbert LA, Villalta JE, Torigoe SE, Tjian R, Weissman JS. Author response: Nucleosomes impede Cas9 access to DNA in vivo and in vitro Elife. DOI: 10.7554/Elife.12677.022  0.313
2016 Zhang Z, English BP, Grimm JB, Kazane SA, Hu W, Tsai A, Inouye C, You C, Piehler J, Schultz PG, Lavis LD, Revyakin A, Tjian R. Rapid dynamics of general transcription factor TFIIB binding during preinitiation complex assembly revealed by single-molecule analysis Genes and Development. 30: 2106-2118. DOI: 10.1101/gad.285395.116  0.342
2016 Zhang Z, Boskovic Z, Hussain M, Hu W, Inouye C, Koehler A, Schreiber S, Tjian R. Chemical Perturbation of an Intrinsically Disordered Region of TFIID Distinguishes de novo Transcription Initiation from Reinitiation Biophysical Journal. 110: 557a. DOI: 10.1016/J.Bpj.2015.11.2980  0.405
2015 Zhang ET, He Y, Grob P, Fong YW, Nogales E, Tjian R. Architecture of the human XPC DNA repair and stem cell coactivator complex. Proceedings of the National Academy of Sciences of the United States of America. 112: 14817-22. PMID 26627236 DOI: 10.1073/Pnas.1520104112  0.423
2015 Knight SC, Xie L, Deng W, Guglielmi B, Witkowsky LB, Bosanac L, Zhang ET, El Beheiry M, Masson JB, Dahan M, Liu Z, Doudna JA, Tjian R. Dynamics of CRISPR-Cas9 genome interrogation in living cells. Science (New York, N.Y.). 350: 823-6. PMID 26564855 DOI: 10.1126/Science.Aac6572  0.552
2015 Li L, Martinez SS, Hu W, Liu Z, Tjian R. A specific E3 ligase/deubiquitinase pair modulates TBP protein levels during muscle differentiation. Elife. 4. PMID 26393420 DOI: 10.7554/Elife.08536  0.476
2015 Deng W, Shi X, Tjian R, Lionnet T, Singer RH. CASFISH: CRISPR/Cas9-mediated in situ labeling of genomic loci in fixed cells. Proceedings of the National Academy of Sciences of the United States of America. 112: 11870-5. PMID 26324940 DOI: 10.1073/Pnas.1515692112  0.371
2015 Cattoglio C, Zhang ET, Grubisic I, Chiba K, Fong YW, Tjian R. Functional and mechanistic studies of XPC DNA-repair complex as transcriptional coactivator in embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 112: E2317-26. PMID 25901318 DOI: 10.1073/Pnas.1505569112  0.515
2015 Zhang Z, Boskovic Z, Hussain MM, Hu W, Inouye C, Kim H, Abole AK, Doud MK, Lewis TA, Koehler AN, Schreiber SL, Tjian R. Author response: Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation Elife. DOI: 10.7554/Elife.07777.021  0.34
2014 Liu Z, Legant WR, Chen BC, Li L, Grimm JB, Lavis LD, Betzig E, Tjian R. 3D imaging of Sox2 enhancer clusters in embryonic stem cells. Elife. 3: e04236. PMID 25537195 DOI: 10.7554/Elife.04236  0.519
2014 Fong YW, Ho JJ, Inouye C, Tjian R. The dyskerin ribonucleoprotein complex as an OCT4/SOX2 coactivator in embryonic stem cells. Elife. 3. PMID 25407680 DOI: 10.7554/Elife.03573  0.447
2014 Herrera FJ, Yamaguchi T, Roelink H, Tjian R. Core promoter factor TAF9B regulates neuronal gene expression. Elife. 3: e02559. PMID 25006164 DOI: 10.7554/Elife.02559  0.469
2014 Levine M, Cattoglio C, Tjian R. Looping back to leap forward: transcription enters a new era. Cell. 157: 13-25. PMID 24679523 DOI: 10.1016/J.Cell.2014.02.009  0.498
2014 Chen J, Zhang Z, Li L, Chen BC, Revyakin A, Hajj B, Legant W, Dahan M, Lionnet T, Betzig E, Tjian R, Liu Z. Single-molecule dynamics of enhanceosome assembly in embryonic stem cells. Cell. 156: 1274-85. PMID 24630727 DOI: 10.1016/J.Cell.2014.01.062  0.545
2014 Lolas M, Valenzuela PD, Tjian R, Liu Z. Charting Brachyury-mediated developmental pathways during early mouse embryogenesis. Proceedings of the National Academy of Sciences of the United States of America. 111: 4478-83. PMID 24616493 DOI: 10.1073/Pnas.1402612111  0.492
2014 Zhang Z, Revyakin A, Grimm JB, Lavis LD, Tjian R. Single-molecule tracking of the transcription cycle by sub-second RNA detection. Elife. 3: e01775. PMID 24473079 DOI: 10.7554/Elife.01775  0.362
2014 Liu Z, Legant WR, Chen B, Li L, Grimm JB, Lavis LD, Betzig E, Tjian R. Author response: 3D imaging of Sox2 enhancer clusters in embryonic stem cells Elife. DOI: 10.7554/Elife.04236.035  0.396
2014 Herrera FJ, Yamaguchi T, Roelink H, Tjian R. Author response: Core promoter factor TAF9B regulates neuronal gene expression Elife. DOI: 10.7554/Elife.02559.018  0.386
2014 Kong NR, Chai L, Winoto A, Tjian R. Mechanisms of MEF2C-Dependent Transcription in Lymphoid Differentiation Blood. 124: 4341-4341. DOI: 10.1182/Blood.V124.21.4341.4341  0.523
2013 Fong YW, Cattoglio C, Tjian R. The intertwined roles of transcription and repair proteins. Molecular Cell. 52: 291-302. PMID 24207023 DOI: 10.1016/J.Molcel.2013.10.018  0.426
2013 Zhou H, Grubisic I, Zheng K, He Y, Wang PJ, Kaplan T, Tjian R. Taf7l cooperates with Trf2 to regulate spermiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 16886-91. PMID 24082143 DOI: 10.1073/Pnas.1317034110  0.411
2013 Guglielmi B, La Rochelle N, Tjian R. Gene-specific transcriptional mechanisms at the histone gene cluster revealed by single-cell imaging. Molecular Cell. 51: 480-92. PMID 23973376 DOI: 10.1016/J.Molcel.2013.08.009  0.497
2013 Zhou H, Kaplan T, Li Y, Grubisic I, Zhang Z, Wang PJ, Eisen MB, Tjian R. Dual functions of TAF7L in adipocyte differentiation. Elife. 2: e00170. PMID 23326641 DOI: 10.7554/Elife.00170  0.499
2013 Zhang Z, Revyakin A, Grimm JB, Lavis LD, Tjian R. Author response: Single-molecule tracking of the transcription cycle by sub-second RNA detection Elife. DOI: 10.7554/Elife.01775.017  0.363
2013 Zhang Z, Revyakin A, Coleman R, Chu S, Tjian R. Single-Molecule Insights on Human RNA Polymerase II Transcription Regulation: Assembly of the Pre-Initiation Complex and the Roles of Activators Biophysical Journal. 104: 365a-366a. DOI: 10.1016/J.Bpj.2012.11.2029  0.472
2012 Revyakin A, Zhang Z, Coleman RA, Li Y, Inouye C, Lucas JK, Park SR, Chu S, Tjian R. Transcription initiation by human RNA polymerase II visualized at single-molecule resolution. Genes & Development. 26: 1691-702. PMID 22810624 DOI: 10.1101/Gad.194936.112  0.402
2012 Fong YW, Cattoglio C, Yamaguchi T, Tjian R. Transcriptional regulation by coactivators in embryonic stem cells. Trends in Cell Biology. 22: 292-8. PMID 22572610 DOI: 10.1016/J.Tcb.2012.04.002  0.447
2011 Fong YW, Inouye C, Yamaguchi T, Cattoglio C, Grubisic I, Tjian R. A DNA repair complex functions as an Oct4/Sox2 coactivator in embryonic stem cells. Cell. 147: 120-31. PMID 21962512 DOI: 10.1016/J.Cell.2011.08.038  0.332
2011 Liu Z, Scannell DR, Eisen MB, Tjian R. Control of embryonic stem cell lineage commitment by core promoter factor, TAF3. Cell. 146: 720-31. PMID 21884934 DOI: 10.1016/J.Cell.2011.08.005  0.56
2011 Yao J, Tjian R. Sub-nuclear compartmentalization of core promoter factors and target genes. Cell Cycle (Georgetown, Tex.). 10: 2405-6. PMID 21670597 DOI: 10.4161/Cc.10.15.16199  0.541
2011 D'Alessio JA, Ng R, Willenbring H, Tjian R. Core promoter recognition complex changes accompany liver development. Proceedings of the National Academy of Sciences of the United States of America. 108: 3906-11. PMID 21368148 DOI: 10.1073/Pnas.1100640108  0.832
2011 Yao J, Fetter RD, Hu P, Betzig E, Tjian R. Subnuclear segregation of genes and core promoter factors in myogenesis. Genes & Development. 25: 569-80. PMID 21357673 DOI: 10.1101/Gad.2021411  0.633
2011 Pertsinidis A, Park SR, Coleman R, Revyakin A, Tjian R, Chu S. Single-Molecule Studies of Human RNA Polymerase Ii Transcription Initiation: Core-Promoter Recognition Biophysical Journal. 100: 65a. DOI: 10.1016/J.Bpj.2010.12.553  0.501
2011 Revyakin A, Zhang Z, Coleman R, Tsai Y, Li Y, Ryul Park S, Pertsinidis A, Lucas J, Korlach J, Chu S, Tjian R. Assembly and Regulation of the Human RNA Polymerase II Preinitiation Complex: A Single-Molecule Approach to a Complex Biological System Biophysical Journal. 100: 10a. DOI: 10.1016/J.Bpj.2010.12.263  0.401
2010 Goodrich JA, Tjian R. Unexpected roles for core promoter recognition factors in cell-type-specific transcription and gene regulation. Nature Reviews. Genetics. 11: 549-58. PMID 20628347 DOI: 10.1038/Nrg2847  0.718
2010 Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, ... ... Tjian RT, et al. Climate change and the integrity of science. Science (New York, N.Y.). 328: 689-90. PMID 20448167 DOI: 10.1126/Science.328.5979.689  0.569
2009 D'Alessio JA, Wright KJ, Tjian R. Shifting players and paradigms in cell-specific transcription. Molecular Cell. 36: 924-31. PMID 20064459 DOI: 10.1016/J.Molcel.2009.12.011  0.841
2009 Liu WL, Coleman RA, Ma E, Grob P, Yang JL, Zhang Y, Dailey G, Nogales E, Tjian R. Structures of three distinct activator-TFIID complexes. Genes & Development. 23: 1510-21. PMID 19571180 DOI: 10.1101/Gad.1790709  0.367
2009 Darzacq X, Yao J, Larson DR, Causse SZ, Bosanac L, de Turris V, Ruda VM, Lionnet T, Zenklusen D, Guglielmi B, Tjian R, Singer RH. Imaging transcription in living cells. Annual Review of Biophysics. 38: 173-96. PMID 19416065 DOI: 10.1146/Annurev.Biophys.050708.133728  0.735
2009 Wright KJ, Tjian R. Wnt signaling targets ETO coactivation domain of TAF4/TFIID in vivo. Proceedings of the National Academy of Sciences of the United States of America. 106: 55-60. PMID 19116271 DOI: 10.1073/Pnas.0811914106  0.461
2008 Deato MD, Tjian R. An unexpected role of TAFs and TRFs in skeletal muscle differentiation: switching core promoter complexes. Cold Spring Harbor Symposia On Quantitative Biology. 73: 217-25. PMID 19022758 DOI: 10.1101/sqb.2008.73.028  0.848
2008 Hu P, Geles KG, Paik JH, DePinho RA, Tjian R. Codependent activators direct myoblast-specific MyoD transcription. Developmental Cell. 15: 534-46. PMID 18854138 DOI: 10.1016/J.Devcel.2008.08.018  0.533
2008 Deato MD, Marr MT, Sottero T, Inouye C, Hu P, Tjian R. MyoD targets TAF3/TRF3 to activate myogenin transcription. Molecular Cell. 32: 96-105. PMID 18851836 DOI: 10.1016/J.Molcel.2008.09.009  0.839
2008 Hsu JY, Juven-Gershon T, Marr MT, Wright KJ, Tjian R, Kadonaga JT. TBP, Mot1, and NC2 establish a regulatory circuit that controls DPE-dependent versus TATA-dependent transcription. Genes & Development. 22: 2353-8. PMID 18703680 DOI: 10.1101/Gad.1681808  0.792
2008 Gao X, Tate P, Hu P, Tjian R, Skarnes WC, Wang Z. ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a. Proceedings of the National Academy of Sciences of the United States of America. 105: 6656-61. PMID 18448678 DOI: 10.1073/Pnas.0801802105  0.411
2008 Kwon SY, Xiao H, Glover BP, Tjian R, Wu C, Badenhorst P. The nucleosome remodeling factor (NURF) regulates genes involved in Drosophila innate immunity. Developmental Biology. 316: 538-47. PMID 18334252 DOI: 10.1016/J.Ydbio.2008.01.033  0.521
2008 King N, Westbrook MJ, Young SL, Kuo A, Abedin M, Chapman J, Fairclough S, Hellsten U, Isogai Y, Letunic I, Marr M, Pincus D, Putnam N, Rokas A, Wright KJ, ... ... Tjian R, et al. The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans. Nature. 451: 783-8. PMID 18273011 DOI: 10.1038/Nature06617  0.657
2008 Liu WL, Coleman RA, Grob P, King DS, Florens L, Washburn MP, Geles KG, Yang JL, Ramey V, Nogales E, Tjian R. Structural changes in TAF4b-TFIID correlate with promoter selectivity. Molecular Cell. 29: 81-91. PMID 18206971 DOI: 10.1016/J.Molcel.2007.11.003  0.475
2007 Isogai Y, Keles S, Prestel M, Hochheimer A, Tjian R. Transcription of histone gene cluster by differential core-promoter factors. Genes & Development. 21: 2936-49. PMID 17978101 DOI: 10.1101/Gad.1608807  0.691
2007 Deato MD, Tjian R. Switching of the core transcription machinery during myogenesis. Genes & Development. 21: 2137-49. PMID 17704303 DOI: 10.1101/Gad.1583407  0.855
2007 Marr MT, D'Alessio JA, Puig O, Tjian R. IRES-mediated functional coupling of transcription and translation amplifies insulin receptor feedback. Genes & Development. 21: 175-83. PMID 17234883 DOI: 10.1101/Gad.1506407  0.812
2007 Isogai Y, Takada S, Tjian R, Kele? S. Novel TRF1/BRF target genes revealed by genome-wide analysis of Drosophila Pol III transcription. The Embo Journal. 26: 79-89. PMID 17170711 DOI: 10.1038/Sj.Emboj.7601448  0.688
2006 Wright KJ, Marr MT, Tjian R. TAF4 nucleates a core subcomplex of TFIID and mediates activated transcription from a TATA-less promoter. Proceedings of the National Academy of Sciences of the United States of America. 103: 12347-52. PMID 16895980 DOI: 10.1073/Pnas.0605499103  0.572
2006 Yang F, Vought BW, Satterlee JS, Walker AK, Jim Sun ZY, Watts JL, DeBeaumont R, Saito RM, Hyberts SG, Yang S, Macol C, Iyer L, Tjian R, van den Heuvel S, Hart AC, et al. An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis. Nature. 442: 700-4. PMID 16799563 DOI: 10.1038/Nature04942  0.469
2006 Marr MT, Isogai Y, Wright KJ, Tjian R. Coactivator cross-talk specifies transcriptional output. Genes & Development. 20: 1458-69. PMID 16751183 DOI: 10.1101/Gad.1418806  0.713
2006 Puig O, Tjian R. Nutrient availability and growth: regulation of insulin signaling by dFOXO/FOXO1. Cell Cycle (Georgetown, Tex.). 5: 503-5. PMID 16552183 DOI: 10.4161/Cc.5.5.2501  0.314
2006 Grob P, Cruse MJ, Inouye C, Peris M, Penczek PA, Tjian R, Nogales E. Cryo-electron microscopy studies of human TFIID: conformational breathing in the integration of gene regulatory cues. Structure (London, England : 1993). 14: 511-20. PMID 16531235 DOI: 10.1016/J.Str.2005.11.020  0.432
2006 Geles KG, Freiman RN, Liu WL, Zheng S, Voronina E, Tjian R. Cell-type-selective induction of c-jun by TAF4b directs ovarian-specific transcription networks. Proceedings of the National Academy of Sciences of the United States of America. 103: 2594-9. PMID 16473943 DOI: 10.1073/Pnas.0510764103  0.752
2005 Zhai W, Jeong H, Cui L, Krainc D, Tjian R. In vitro analysis of huntingtin-mediated transcriptional repression reveals multiple transcription factor targets. Cell. 123: 1241-53. PMID 16377565 DOI: 10.1016/J.Cell.2005.10.030  0.514
2005 Puig O, Tjian R. Transcriptional feedback control of insulin receptor by dFOXO/FOXO1. Genes & Development. 19: 2435-46. PMID 16230533 DOI: 10.1101/Gad.1340505  0.342
2005 Falender AE, Freiman RN, Geles KG, Lo KC, Hwang K, Lamb DJ, Morris PL, Tjian R, Richards JS. Maintenance of spermatogenesis requires TAF4b, a gonad-specific subunit of TFIID. Genes & Development. 19: 794-803. PMID 15774719 DOI: 10.1101/Gad.1290105  0.723
2005 Leschziner AE, Lemon B, Tjian R, Nogales E. Structural studies of the human PBAF chromatin-remodeling complex. Structure (London, England : 1993). 13: 267-75. PMID 15698570 DOI: 10.1016/J.Str.2004.12.008  0.386
2004 Wang Z, Zhai W, Richardson JA, Olson EN, Meneses JJ, Firpo MT, Kang C, Skarnes WC, Tjian R. Polybromo protein BAF180 functions in mammalian cardiac chamber maturation. Genes & Development. 18: 3106-16. PMID 15601824 DOI: 10.1101/Gad.1238104  0.379
2004 Taatjes DJ, Schneider-Poetsch T, Tjian R. Distinct conformational states of nuclear receptor-bound CRSP-Med complexes. Nature Structural & Molecular Biology. 11: 664-71. PMID 15195149 DOI: 10.1038/Nsmb789  0.326
2004 Taatjes DJ, Tjian R. Structure and function of CRSP/Med2; a promoter-selective transcriptional coactivator complex. Molecular Cell. 14: 675-83. PMID 15175162 DOI: 10.1016/J.Molcel.2004.05.014  0.537
2004 Taatjes DJ, Marr MT, Tjian R. Regulatory diversity among metazoan co-activator complexes. Nature Reviews. Molecular Cell Biology. 5: 403-10. PMID 15122353 DOI: 10.1038/Nrm1369  0.465
2004 Ziegelbauer J, Wei J, Tjian R. Myc-interacting protein 1 target gene profile: a link to microtubules, extracellular signal-regulated kinase, and cell growth. Proceedings of the National Academy of Sciences of the United States of America. 101: 458-63. PMID 14704274 DOI: 10.1073/Pnas.0307562100  0.715
2003 Puig O, Marr MT, Ruhf ML, Tjian R. Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway. Genes & Development. 17: 2006-20. PMID 12893776 DOI: 10.1101/Gad.1098703  0.379
2003 Levine M, Tjian R. Transcription regulation and animal diversity. Nature. 424: 147-51. PMID 12853946 DOI: 10.1038/Nature01763  0.362
2003 Isogai Y, Tjian R. Targeting genes and transcription factors to segregated nuclear compartments. Current Opinion in Cell Biology. 15: 296-303. PMID 12787771 DOI: 10.1016/S0955-0674(03)00052-8  0.676
2003 Hochheimer A, Tjian R. Diversified transcription initiation complexes expand promoter selectivity and tissue-specific gene expression. Genes & Development. 17: 1309-20. PMID 12782648 DOI: 10.1101/Gad.1099903  0.59
2003 Ladurner AG, Inouye C, Jain R, Tjian R. Bromodomains mediate an acetyl-histone encoded antisilencing function at heterochromatin boundaries. Molecular Cell. 11: 365-76. PMID 12620225 DOI: 10.1016/S1097-2765(03)00035-2  0.678
2003 Freiman RN, Tjian R. Regulating the regulators: lysine modifications make their mark. Cell. 112: 11-7. PMID 12526789 DOI: 10.1016/S0092-8674(02)01278-3  0.749
2002 Hochheimer A, Zhou S, Zheng S, Holmes MC, Tjian R. TRF2 associates with DREF and directs promoter-selective gene expression in Drosophila. Nature. 420: 439-45. PMID 12459787 DOI: 10.1038/Nature01167  0.56
2002 Freiman RN, Albright SR, Chu LE, Zheng S, Liang HE, Sha WC, Tjian R. Redundant role of tissue-selective TAF(II)105 in B lymphocytes. Molecular and Cellular Biology. 22: 6564-72. PMID 12192054 DOI: 10.1128/Mcb.22.18.6564-6572.2002  0.731
2002 Freiman RN, Tjian R. Neurodegeneration. A glutamine-rich trail leads to transcription factors. Science (New York, N.Y.). 296: 2149-50. PMID 12077389 DOI: 10.1126/Science.1073845  0.731
2002 Näär AM, Taatjes DJ, Zhai W, Nogales E, Tjian R. Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation. Genes & Development. 16: 1339-44. PMID 12050112 DOI: 10.1101/Gad.987602  0.435
2001 Biggin MD, Tjian R. Transcriptional regulation in Drosophila: the post-genome challenge. Functional & Integrative Genomics. 1: 223-34. PMID 11793241 DOI: 10.1007/S101420000021  0.802
2001 Lemon B, Inouye C, King DS, Tjian R. Selectivity of chromatin-remodelling cofactors for ligand-activated transcription. Nature. 414: 924-8. PMID 11780067 DOI: 10.1038/414924A  0.566
2001 Freiman RN, Albright SR, Zheng S, Sha WC, Hammer RE, Tjian R. Requirement of tissue-selective TBP-associated factor TAFII105 in ovarian development. Science (New York, N.Y.). 293: 2084-7. PMID 11557891 DOI: 10.1126/Science.1061935  0.758
2001 Ziegelbauer J, Shan B, Yager D, Larabell C, Hoffmann B, Tjian R. Transcription factor MIZ-1 is regulated via microtubule association. Molecular Cell. 8: 339-49. PMID 11545736 DOI: 10.1016/S1097-2765(01)00313-6  0.754
2001 Näär AM, Lemon BD, Tjian R. Transcriptional coactivator complexes. Annual Review of Biochemistry. 70: 475-501. PMID 11395415 DOI: 10.1146/Annurev.Biochem.70.1.475  0.546
2000 Lemon B, Tjian R. Orchestrated response: a symphony of transcription factors for gene control. Genes & Development. 14: 2551-69. PMID 11040209 DOI: 10.1101/Gad.831000  0.436
2000 Takada S, Lis JT, Zhou S, Tjian R. A TRF1:BRF complex directs Drosophila RNA polymerase III transcription. Cell. 101: 459-69. PMID 10850489 DOI: 10.1016/S0092-8674(00)80857-0  0.659
2000 Jacobson RH, Ladurner AG, King DS, Tjian R. Structure and function of a human TAFII250 double bromodomain module. Science (New York, N.Y.). 288: 1422-5. PMID 10827952 DOI: 10.1126/Science.288.5470.1422  0.675
2000 Holmes MC, Tjian R. Promoter-selective properties of the TBP-related factor TRF1. Science (New York, N.Y.). 288: 867-70. PMID 10797011 DOI: 10.1126/Science.288.5467.867  0.57
2000 Albright SR, Tjian R. TAFs revisited: more data reveal new twists and confirm old ideas. Gene. 242: 1-13. PMID 10721692 DOI: 10.1016/S0378-1119(99)00495-3  0.576
2000 O'Brien T, Tjian R. Different functional domains of TAFII250 modulate expression of distinct subsets of mammalian genes. Proceedings of the National Academy of Sciences of the United States of America. 97: 2456-61. PMID 10716982 DOI: 10.1073/Pnas.97.6.2456  0.484
1999 Andel F, Ladurner AG, Inouye C, Tjian R, Nogales E. Three-dimensional structure of the human TFIID-IIA-IIB complex. Science (New York, N.Y.). 286: 2153-6. PMID 10591646 DOI: 10.1126/Science.286.5447.2153  0.695
1999 Ryu S, Tjian R. Purification of transcription cofactor complex CRSP. Proceedings of the National Academy of Sciences of the United States of America. 96: 7137-42. PMID 10377381 DOI: 10.1073/Pnas.96.13.7137  0.611
1999 Näär AM, Beaurang PA, Zhou S, Abraham S, Solomon W, Tjian R. Composite co-activator ARC mediates chromatin-directed transcriptional activation. Nature. 398: 828-32. PMID 10235267 DOI: 10.1038/19789  0.526
1999 Rabenstein MD, Zhou S, Lis JT, Tjian R. TATA box-binding protein (TBP)-related factor 2 (TRF2), a third member of the TBP family. Proceedings of the National Academy of Sciences of the United States of America. 96: 4791-6. PMID 10220372 DOI: 10.1073/Pnas.96.9.4791  0.726
1999 Ryu S, Zhou S, Ladurner AG, Tjian R. The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1. Nature. 397: 446-50. PMID 9989412 DOI: 10.1038/17141  0.743
1998 Näär AM, Ryu S, Tjian R. Cofactor requirements for transcriptional activation by Sp1. Cold Spring Harbor Symposia On Quantitative Biology. 63: 189-99. PMID 10384283 DOI: 10.1101/Sqb.1998.63.189  0.518
1998 Sauer F, Wassarman DA, Rubin GM, Tjian R. Retraction. TAF(II)s mediate activation of transcription in the Drosophila embryo. Cell. 95: following 573. PMID 9867425 DOI: 10.1016/S0092-8674(02)09541-7  0.68
1998 Zhou J, Zwicker J, Szymanski P, Levine M, Tjian R. TAFII mutations disrupt Dorsal activation in the Drosophila embryo. Proceedings of the National Academy of Sciences of the United States of America. 95: 13483-8. PMID 9811826 DOI: 10.1073/Pnas.95.23.13483  0.489
1998 Näär AM, Beaurang PA, Robinson KM, Oliner JD, Avizonis D, Scheek S, Zwicker J, Kadonaga JT, Tjian R. Chromatin, TAFs, and a novel multiprotein coactivator are required for synergistic activation by Sp1 and SREBP-1a in vitro. Genes & Development. 12: 3020-31. PMID 9765204 DOI: 10.1101/Gad.12.19.3020  0.768
1998 O'Brien T, Tjian R. Functional analysis of the human TAFII250 N-terminal kinase domain. Molecular Cell. 1: 905-11. PMID 9660973 DOI: 10.1016/S1097-2765(00)80089-1  0.346
1998 Yokomori K, Verrijzer CP, Tjian R. An interplay between TATA box-binding protein and transcription factors IIE and IIA modulates DNA binding and transcription. Proceedings of the National Academy of Sciences of the United States of America. 95: 6722-7. PMID 9618479 DOI: 10.1073/Pnas.95.12.6722  0.564
1998 Cutler G, Perry KM, Tjian R. Adf-1 is a nonmodular transcription factor that contains a TAF-binding Myb-like motif. Molecular and Cellular Biology. 18: 2252-61. PMID 9528796 DOI: 10.1128/Mcb.18.4.2252  0.478
1997 Hansen SK, Takada S, Jacobson RH, Lis JT, Tjian R. Transcription properties of a cell type-specific TATA-binding protein, TRF. Cell. 91: 71-83. PMID 9335336 DOI: 10.1016/S0092-8674(01)80010-6  0.711
1997 Wang EH, Zou S, Tjian R. TAFII250-dependent transcription of cyclin A is directed by ATF activator proteins. Genes & Development. 11: 2658-69. PMID 9334328 DOI: 10.1101/Gad.11.20.2658  0.558
1997 Thut CJ, Goodrich JA, Tjian R. Repression of p53-mediated transcription by MDM2: a dual mechanism. Genes & Development. 11: 1974-86. PMID 9271120 DOI: 10.1101/Gad.11.15.1974  0.679
1997 Sauer F, Tjian R. Mechanisms of transcriptional activation: differences and similarities between yeast, Drosophila, and man. Current Opinion in Genetics & Development. 7: 176-81. PMID 9115422 DOI: 10.1016/S0959-437X(97)80126-8  0.713
1997 Heix J, Zomerdijk JC, Ravanpay A, Tjian R, Grummt I. Cloning of murine RNA polymerase I-specific TAF factors: conserved interactions between the subunits of the species-specific transcription initiation factor TIF-IB/SL1. Proceedings of the National Academy of Sciences of the United States of America. 94: 1733-8. PMID 9050847 DOI: 10.1073/Pnas.94.5.1733  0.512
1997 Tjian R. The biochemistry of transcription by RNA polymerasb II developing an integrated in vitro activation assay Faseb Journal. 11: A1013.  0.303
1996 Sauer F, Wassarman DA, Rubin GM, Tjian R. TAF(II)s mediate activation of transcription in the Drosophila embryo. Cell. 87: 1271-84. PMID 8980233 DOI: 10.1016/S0092-8674(00)81822-X  0.752
1996 Oliner JD, Andresen JM, Hansen SK, Zhou S, Tjian R. SREBP transcriptional activity is mediated through an interaction with the CREB-binding protein. Genes & Development. 10: 2903-11. PMID 8918891 DOI: 10.1101/Gad.10.22.2903  0.553
1996 Verrijzer CP, Tjian R. TAFs mediate transcriptional activation and promoter selectivity. Trends in Biochemical Sciences. 21: 338-42. PMID 8870497 DOI: 10.1016/S0968-0004(96)10044-X  0.527
1996 Dikstein R, Zhou S, Tjian R. Human TAFII 105 is a cell type-specific TFIID subunit related to hTAFII130. Cell. 87: 137-46. PMID 8858156 DOI: 10.1016/S0092-8674(00)81330-6  0.414
1996 Chen JL, Tjian R. Reconstitution of TATA-binding protein-associated factor/TATA-binding protein complexes for in vitro transcription. Methods in Enzymology. 273: 208-17. PMID 8791614  0.369
1996 Tjian R. The biochemistry of transcription in eukaryotes: a paradigm for multisubunit regulatory complexes. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 351: 491-9. PMID 8735271 DOI: 10.1098/Rstb.1996.0047  0.618
1996 Jacobson RH, Tjian R. Transcription factor IIA: a structure with multiple functions. Science (New York, N.Y.). 272: 827-8. PMID 8629011 DOI: 10.1126/Science.272.5263.827  0.453
1996 Dikstein R, Ruppert S, Tjian R. TAFII250 is a bipartite protein kinase that phosphorylates the base transcription factor RAP74. Cell. 84: 781-90. PMID 8625415 DOI: 10.1016/S0092-8674(00)81055-7  0.467
1996 Goodrich JA, Cutler G, Tjian R. Contacts in context: promoter specificity and macromolecular interactions in transcription. Cell. 84: 825-30. PMID 8601306 DOI: 10.1016/S0092-8674(00)81061-2  0.758
1996 Zeidler MP, Yokomori K, Tjian R, Mlodzik M. Drosophila TFIIA-S is up-regulated and required during Ras-mediated photoreceptor determination. Genes & Development. 10: 50-9. PMID 8557194 DOI: 10.1101/Gad.10.1.50  0.423
1995 Sauer F, Hansen SK, Tjian R. DNA template and activator-coactivator requirements for transcriptional synergism by Drosophila bicoid. Science (New York, N.Y.). 270: 1825-8. PMID 8525377 DOI: 10.1126/Science.270.5243.1825  0.727
1995 Sauer F, Hansen SK, Tjian R. Multiple TAFIIs directing synergistic activation of transcription. Science (New York, N.Y.). 270: 1783-8. PMID 8525367 DOI: 10.1126/Science.270.5243.1783  0.735
1995 Thut CJ, Chen JL, Klemm R, Tjian R. p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60. Science (New York, N.Y.). 267: 100-4. PMID 7809597 DOI: 10.1126/Science.7809597  0.498
1995 Lichtsteiner S, Tjian R. Synergistic activation of transcription by UNC-86 and MEC-3 in Caenorhabditis elegans embryo extracts. The Embo Journal. 14: 3937-45. PMID 7664734 DOI: 10.1002/J.1460-2075.1995.Tb00065.X  0.571
1995 Hansen SK, Tjian R. TAFs and TFIIA mediate differential utilization of the tandem Adh promoters. Cell. 82: 565-75. PMID 7664336 DOI: 10.1016/0092-8674(95)90029-2  0.511
1995 O'Neill EM, Ellis MC, Rubin GM, Tjian R. Functional domain analysis of glass, a zinc-finger-containing transcription factor in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 92: 6557-61. PMID 7604032 DOI: 10.1073/Pnas.92.14.6557  0.633
1995 Verrijzer CP, Chen JL, Yokomori K, Tjian R. Binding of TAFs to core elements directs promoter selectivity by RNA polymerase II. Cell. 81: 1115-25. PMID 7600579 DOI: 10.1016/S0092-8674(05)80016-9  0.529
1995 Klemm RD, Goodrich JA, Zhou S, Tjian R. Molecular cloning and expression of the 32-kDa subunit of human TFIID reveals interactions with VP16 and TFIIB that mediate transcriptional activation. Proceedings of the National Academy of Sciences of the United States of America. 92: 5788-92. PMID 7597030 DOI: 10.1073/Pnas.92.13.5788  0.724
1995 Ruppert S, Tjian R. Human TAFII250 interacts with RAP74: implications for RNA polymerase II initiation. Genes & Development. 9: 2747-55. PMID 7590250  0.47
1995 Beckmann H, Chen JL, O'Brien T, Tjian R. Coactivator and promoter-selective properties of RNA polymerase I TAFs. Science (New York, N.Y.). 270: 1506-9. PMID 7491500 DOI: 10.1126/Science.270.5241.1506  0.494
1994 Tjian R. The biochemistry of transcription and gene regulation Harvey Lectures. 90: 19-39. PMID 8803317  0.377
1994 Wang EH, Tjian R. Promoter-selective transcriptional defect in cell cycle mutant ts13 rescued by hTAFII250 Science. 263: 811-814. PMID 8303298 DOI: 10.1126/Science.8303298  0.473
1994 Gill G, Pascal E, Tseng ZH, Tjian R. A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation. Proceedings of the National Academy of Sciences of the United States of America. 91: 192-6. PMID 8278363 DOI: 10.1073/Pnas.91.1.192  0.692
1994 Verrijzer CP, Yokomori K, Chen JL, Tjian R. Drosophila TAFII 150: Similarity to yeast gene TSM-1 and specific binding to core promoter DNA Science. 264: 933-941. PMID 8178153 DOI: 10.1126/Science.8178153  0.56
1994 Tjian R, Maniatis T. Transcriptional activation: A complex puzzle with few easy pieces Cell. 77: 5-8. PMID 8156597 DOI: 10.1016/0092-8674(94)90227-5  0.623
1994 Goodrich JA, Tjian R. Transcription factors IIE and IIH and ATP hydrolysis direct promoter clearance by RNA polymerase II Cell. 77: 145-156. PMID 8156590 DOI: 10.1016/0092-8674(94)90242-9  0.729
1994 Kaffman A, Herskowitz I, Tjian R, O'Shea EK. Phosphorylation of the transcription factor PHO4 by a cyclin-CDK complex, PHO80-PHO85. Science (New York, N.Y.). 263: 1153-6. PMID 8108735 DOI: 10.1126/Science.8108735  0.761
1994 O'Neill EM, Rebay I, Tjian R, Rubin GM. The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway. Cell. 78: 137-47. PMID 8033205 DOI: 10.1016/0092-8674(94)90580-0  0.611
1994 Tansey WP, Ruppert S, Tjian R, Herr W. Multiple regions of TBP participate in the response to transcriptional activators in vivo Genes and Development. 8: 2756-2769. PMID 7958931 DOI: 10.1101/Gad.8.22.2756  0.703
1994 Yokomori K, Zeidler MP, Chen JL, Verrijzer CP, Mlodzik M, Tjian R. Drosophila TFIIA directs cooperative DNA binding with TBP and mediates transcriptional activation. Genes & Development. 8: 2313-23. PMID 7958898 DOI: 10.1101/Gad.8.19.2313  0.52
1994 Maxon ME, Tjian R. Transcriptional activity of transcription factor IIE is dependent on zinc binding Proceedings of the National Academy of Sciences of the United States of America. 91: 9529-9533. PMID 7937800 DOI: 10.1073/Pnas.91.20.9529  0.547
1994 Maxon ME, Goodrich JA, Tjian R. Transcription factor IIE binds preferentially to RNA polymerase IIa and recruits TFIIH: A model for promoter clearance Genes and Development. 8: 515-524. PMID 7926747 DOI: 10.1101/Gad.8.5.515  0.725
1994 Chen JL, Attardi LD, Verrijzer CP, Yokomori K, Tjian R. Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators Cell. 79: 93-105. PMID 7923382 DOI: 10.1016/0092-8674(94)90403-0  0.526
1994 Goodrich JA, Tjian R. TBP-TAF complexes: selectivity factors for eukaryotic transcription Current Opinion in Cell Biology. 6: 403-409. PMID 7917332 DOI: 10.1016/0955-0674(94)90033-7  0.704
1994 Zomerdijk JCBM, Beckmann H, Comai L, Tjian R. Assembly of transcriptionally active RNA polymerase I initiation factor SL1 from recombinant subunits Science. 266: 2015-2018. PMID 7801130 DOI: 10.1126/Science.7801130  0.498
1994 Comai L, Zomerdijk JCBM, Beckmann H, Zhou S, Admon A, Tjian R. Reconstitution of transcription factor SL1: Exclusive binding of TBP by SL1 or TFIID subunits Science. 266: 1966-1972. PMID 7801123 DOI: 10.1126/Science.7801123  0.53
1993 Dynlacht BD, Weinzierl RO, Admon A, Tjian R. The dTAFII80 subunit of Drosophila TFIID contains beta-transducin repeats. Nature. 363: 176-9. PMID 8483503 DOI: 10.1038/363176A0  0.73
1993 Weinzierl RO, Dynlacht BD, Tjian R. Largest subunit of Drosophila transcription factor IID directs assembly of a complex containing TBP and a coactivator. Nature. 362: 511-7. PMID 8464492 DOI: 10.1038/362511A0  0.725
1993 Crowley TE, Hoey T, Liu JK, Jan YN, Jan LY, Tjian R. A new factor related to TATA-binding protein has highly restricted expression patterns in Drosophila. Nature. 361: 557-61. PMID 8429912 DOI: 10.1038/361557A0  0.557
1993 Lichtsteiner S, Tjian R. Cloning and properties of the Caenorhabditis elegans TATA-box-binding protein Proceedings of the National Academy of Sciences of the United States of America. 90: 9673-9677. PMID 8415761 DOI: 10.1073/Pnas.90.20.9673  0.466
1993 Attardi LD, Tjian R. Drosophila tissue-specific transcription factor NTF-1 contains a novel isoleucinerich activation motif Genes and Development. 7: 1341-1353. PMID 8330738  0.42
1993 Yokomori K, Chen JL, Admon A, Zhou S, Tjian R. Molecular cloning and characterization of dTAFII30α and dTAFII30β: Two small subunits of Drosophila TFIID Genes and Development. 7: 2587-2597. PMID 8276241 DOI: 10.1101/Gad.7.12B.2587  0.413
1993 Weinzierl RO, Ruppert S, Dynlacht BD, Tanese N, Tjian R. Cloning and expression of Drosophila TAFII60 and human TAFII70 reveal conserved interactions with other subunits of TFIID. The Embo Journal. 12: 5303-9. PMID 8262073 DOI: 10.1002/J.1460-2075.1993.Tb06226.X  0.709
1993 Attardi LD, Von Seggern D, Tjian R. Ectopic expression of wild-type or a dominant-negative mutant of transcription factor NTF-1 disrupts normal Drosophila development. Proceedings of the National Academy of Sciences of the United States of America. 90: 10563-7. PMID 8248145  0.401
1993 Yokomori K, Admon A, Goodrich JA, Chen JL, Tjian R. Drosophila TFIIA-L is processed into two subunits that are associated with the TBP/TAF complex Genes and Development. 7: 2235-2245. PMID 8224849 DOI: 10.1101/Gad.7.11.2235  0.663
1993 Goodrich JA, Hoey T, Thut CJ, Admon A, Tjian R. Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB. Cell. 75: 519-30. PMID 8221891 DOI: 10.1016/0092-8674(93)90386-5  0.733
1993 Tanese N, Tjian R. Coactivators and TAFs: a new class of eukaryotic transcription factors that connect activators to the basal machinery. Cold Spring Harbor Symposia On Quantitative Biology. 58: 179-85. PMID 7956028  0.342
1993 Ruppert S, Wang EH, Tjian R. Cloning and expression of human TAFII250: A TBP-associated factor implicated in cell-cycle regulation Nature. 362: 175-179. PMID 7680771 DOI: 10.1038/362175A0  0.59
1993 Hoey T, Weinzierl RO, Gill G, Chen JL, Dynlacht BD, Tjian R. Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators. Cell. 72: 247-60. PMID 7678780 DOI: 10.1016/0092-8674(93)90664-C  0.782
1992 England BP, Admon A, Tjian R. Cloning of Drosophila transcription factor Adf-1 reveals homology to Myb oncoproteins Proceedings of the National Academy of Sciences of the United States of America. 89: 683-687. PMID 1731341 DOI: 10.1073/Pnas.89.2.683  0.503
1992 Pugh BF, Tjian R. Diverse transcriptional functions of the multisubunit eukaryotic TFIID complex Journal of Biological Chemistry. 267: 679-682. PMID 1730659  0.334
1992 Baichwal VR, Park A, Tjian R. The cell-type-specific activator region of c-Jun juxtaposes constitutive and negatively regulated domains Genes and Development. 6: 1493-1502. PMID 1644291 DOI: 10.1101/Gad.6.8.1493  0.433
1992 Gill G, Tjian R. Eukaryotic coactivators associated with the TATA box binding protein. Current Opinion in Genetics & Development. 2: 236-42. PMID 1638117 DOI: 10.1016/S0959-437X(05)80279-5  0.68
1992 Comai L, Tanese N, Tjian R. The TATA-binding protein and associated factors are integral components of the RNA polymerase I transcription factor, SL1. Cell. 68: 965-76. PMID 1547496 DOI: 10.1016/0092-8674(92)90039-F  0.547
1992 Jantzen HM, Chow AM, King DS, Tjian R. Multiple domains of the RNA polymerase I activator hUBF interact with the TATA-binding protein complex hSL1 to mediate transcription Genes and Development. 6: 1950-1963. PMID 1398072  0.431
1992 Courey AJ, Tjian R. 28 Mechanisms of Transcriptional Control as Revealed by Studies of Human Transcription Factor Sp1 Cold Spring Harbor Monograph Archive. 743-769. DOI: 10.1101/087969425.22B.743  0.597
1991 Gill G, Tjian R. A highly conserved domain of TFIID displays species specificity in vivo. Cell. 65: 333-40. PMID 2015627 DOI: 10.1016/0092-8674(91)90166-V  0.604
1991 Williams T, Tjian R. Analysis of the DNA-binding and activation properties of the human transcription factor AP-2 Genes and Development. 5: 670-682. PMID 2010091 DOI: 10.1101/Gad.5.4.670  0.508
1991 Williams T, Tjian R. Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteins Science. 251: 1067-1071. PMID 1998122 DOI: 10.1126/Science.1998122  0.448
1991 Mitchell PJ, Timmons PM, Hébert JM, Rigby PWJ, Tjian R. Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis Genes and Development. 5: 105-119. PMID 1989904 DOI: 10.1101/Gad.5.1.105  0.38
1991 Peterson MG, Inostroza J, Maxon ME, Flores O, Admon A, Reinberg D, Tjian R. Structure and functional properties of human general transcription factor IIE Nature. 354: 369-373. PMID 1956398 DOI: 10.1038/354369A0  0.531
1991 Dynlacht BD, Hoey T, Tjian R. Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation. Cell. 66: 563-76. PMID 1907890 DOI: 10.1016/0092-8674(81)90019-2  0.75
1991 Baichwal VR, Park A, Tjian R. v-Src and EJ Ras alleviate repression of c-Jun by a cell-specific inhibitor Nature. 352: 165-168. PMID 1906140 DOI: 10.1038/352165A0  0.389
1991 Pascal E, Tjian R. Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism Genes and Development. 5: 1646-1656. PMID 1885006  0.411
1991 Su W, Jackson S, Tjian R, Echols H. DNA looping between sites for transcriptional activation: Self-association of DNA-bound Sp1 Genes and Development. 5: 820-826. PMID 1851121  0.579
1991 Li R, Knight JD, Jackson SP, Tjian R, Botchan MR. Direct interaction between Sp1 and the BPV enhancer E2 protein mediates synergistic activation of transcription. Cell. 65: 493-505. PMID 1850324 DOI: 10.1016/0092-8674(91)90467-D  0.769
1991 Tanese N, Pugh BF, Tjian R. Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex. Genes & Development. 5: 2212-24. PMID 1748279 DOI: 10.1101/Gad.5.12A.2212  0.528
1991 Pugh BF, Tjian R. Transcription from a TATA-less promoter requires a multisubunit TFIID complex Genes and Development. 5: 1935-1945. PMID 1657708  0.467
1990 Bell SP, Jantzen HM, Tjian R. Assembly of alternative multiprotein complexes directs rRNA promoter selectivity. Genes & Development. 4: 943-54. PMID 2384215 DOI: 10.1101/Gad.4.6.943  0.695
1990 Peterson MG, Tanese N, Pugh BF, Tjian R. Functional domains and upstream activation properties of cloned human TATA binding protein. Science (New York, N.Y.). 248: 1625-30. PMID 2363050 DOI: 10.1126/Science.2363050  0.513
1990 Jantzen HM, Admon A, Bell SP, Tjian R. Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins. Nature. 344: 830-6. PMID 2330041 DOI: 10.1038/344830A0  0.716
1990 England BP, Heberlein U, Tjian R. Purified Drosophila transcription factor, Adh distal factor-1 (Adf-1), binds to sites in several Drosophila promoters and activates transcription. The Journal of Biological Chemistry. 265: 5086-94. PMID 2318884  0.728
1990 Pugh BF, Tjian R. Mechanism of transcriptional activation by Sp1: Evidence for coactivators Cell. 61: 1187-1197. PMID 2194667 DOI: 10.1016/0092-8674(90)90683-6  0.529
1990 Hoey T, Dynlacht BD, Peterson MG, Pugh BF, Tjian R. Isolation and characterization of the Drosophila gene encoding the TATA box binding protein, TFIID. Cell. 61: 1179-86. PMID 2194666 DOI: 10.1016/0092-8674(90)90682-5  0.737
1990 Jackson SP, MacDonald JJ, Lees-Miller S, Tjian R. GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase Cell. 63: 155-165. PMID 2170018 DOI: 10.1016/0092-8674(90)90296-Q  0.623
1990 Hu YF, Lüscher B, Adinon A, Mermod N, Tjian R. Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity Genes and Development. 4: 1741-1752. PMID 2123466 DOI: 10.1101/Gad.4.10.1741  0.685
1990 Baichwal VR, Tjian R. Control of c-Jun activity by interaction of a cell-specific inhibitor with regulatory domain δ: Differences between v- and c-Jun Cell. 63: 815-825. PMID 2121368 DOI: 10.1016/0092-8674(90)90147-7  0.442
1990 Perkins KK, Admon A, Patel N, Tjian R. The Drosophila Fos-related AP-1 protein is a developmentally regulated transcription factor Genes and Development. 4: 822-834. PMID 2116361 DOI: 10.1101/Gad.4.5.822  0.526
1989 Williams T, Admon A, Lüscher B, Tjian R. Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements. Genes & Development. 2: 1557-69. PMID 3063603 DOI: 10.1101/Gad.2.12A.1557  0.702
1989 Bell SP, Pikaard CS, Reeder RH, Tjian R. Molecular mechanisms governing species-specific transcription of ribosomal RNA. Cell. 59: 489-97. PMID 2805069 DOI: 10.1016/0092-8674(89)90032-9  0.695
1989 Biggin MD, Tjian R. Transcription factors and the control of Drosophila development. Trends in Genetics : Tig. 5: 377-83. PMID 2692246 DOI: 10.1016/0168-9525(89)90173-X  0.76
1989 Mitchell PJ, Tjian R. Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins Science. 245: 371-378. PMID 2667136 DOI: 10.1126/Science.2667136  0.593
1989 Jackson SP, Tjian R. Purification and analysis of RNA polymerase II transcription factors by using wheat germ agglutinin affinity chromatography Proceedings of the National Academy of Sciences of the United States of America. 86: 1781-1785. PMID 2648381 DOI: 10.1073/Pnas.86.6.1781  0.665
1989 Dynlacht BD, Attardi LD, Admon A, Freeman M, Tjian R. Functional analysis of NTF-1, a developmentally regulated Drosophila transcription factor that binds neuronal cis elements. Genes & Development. 3: 1677-88. PMID 2606344 DOI: 10.1101/Gad.3.11.1677  0.749
1989 Biggin MD, Tjian R. A purified Drosophila homeodomain protein represses transcription in vitro. Cell. 58: 433-40. PMID 2569362 DOI: 10.1016/0092-8674(89)90424-8  0.799
1989 Courey AJ, Holtzman DA, Jackson SP, Tjian R. Synergistic activation by the glutamine-rich domains of human transcription factor Sp1. Cell. 59: 827-36. PMID 2512012 DOI: 10.1016/0092-8674(89)90606-5  0.767
1989 Bohmann D, Tjian R. Biochemical analysis of transcriptional activation by Jun: Differential activity of c- and v-Jun Cell. 59: 709-717. PMID 2510934 DOI: 10.1016/0092-8674(89)90017-2  0.46
1989 Mermod N, O'Neill EA, Kelly TJ, Tjian R. The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain. Cell. 58: 741-53. PMID 2504497 DOI: 10.1016/0092-8674(89)90108-6  0.522
1989 Turner R, Tjian R. Leucine repeats and an adjacent DNA binding domain mediate the formation of functional cFos-cJun heterodimers Science. 243: 1689-1694. PMID 2494701  0.382
1989 Lüscher B, Mitchell PJ, Williams T, Tjian R. Regulation of transcription factor AP-2 by the morphogen retinoic acid and by second messengers Genes & Development. 3: 1507-1517. PMID 2482225 DOI: 10.1101/Gad.3.10.1507  0.647
1988 Jones MH, Learned RM, Tjian R. Analysis of clustered point mutations in the human ribosomal RNA gene promoter by transient expression in vivo Proceedings of the National Academy of Sciences of the United States of America. 85: 669-673. PMID 3422449 DOI: 10.1073/Pnas.85.3.669  0.512
1988 Bell SP, Learned RM, Jantzen HM, Tjian R. Functional cooperativity between transcription factors UBF1 and SL1 mediates human ribosomal RNA synthesis. Science (New York, N.Y.). 241: 1192-7. PMID 3413483 DOI: 10.1126/Science.3413483  0.696
1988 Santoro C, Mermod N, Andrews PC, Tjian R. A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs. Nature. 334: 218-24. PMID 3398920 DOI: 10.1038/334218A0  0.517
1988 Heberlein U, Tjian R. Temporal pattern of alcohol dehydrogenase gene transcription reproduced by Drosophila stage-specific embryonic extracts. Nature. 331: 410-5. PMID 3340187 DOI: 10.1038/331410A0  0.662
1988 Perkins KK, Dailey GM, Tjian R. In vitro analysis of the Antennapedia P2 promoter: identification of a new Drosophila transcription factor Genes & Development. 2: 1615-1626. PMID 3215512 DOI: 10.1101/Gad.2.12A.1615  0.54
1988 Bohmann D, Admon A, Turner DR, Tjian R. Transcriptional regulation by the AP-1 family of enhancer-binding proteins: A nuclear target for signal transduction Cold Spring Harbor Symposia On Quantitative Biology. 53: 695-700. PMID 3151183 DOI: 10.1101/Sqb.1988.053.01.079  0.437
1988 Perkins KK, Dailey GM, Tjian R. Novel Jun- and Fos-related proteins in Drosophila are functionally homologous to enhancer factor AP-1 Embo Journal. 7: 4265-4273. PMID 3149584 DOI: 10.1002/J.1460-2075.1988.Tb03324.X  0.477
1988 Courey AJ, Tjian R. Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell. 55: 887-98. PMID 3142690 DOI: 10.1016/0092-8674(88)90144-4  0.761
1988 Jackson SP, Tjian R. O-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation. Cell. 55: 125-33. PMID 3139301 DOI: 10.1016/0092-8674(88)90015-3  0.659
1988 Biggin MD, Bickel S, Benson M, Pirrotta V, Tjian R. Zeste encodes a sequence-specific transcription factor that activates the Ultrabithorax promoter in vitro. Cell. 53: 713-22. PMID 3131017 DOI: 10.1016/0092-8674(88)90089-X  0.808
1988 Rauscher FJ, Cohen DR, Curran T, Bos TJ, Vogt PK, Bohmann D, Tjian R, Franza BR. Fos-associated protein p39 is the product of the jun proto-oncogene. Science (New York, N.Y.). 240: 1010-6. PMID 3130660 DOI: 10.1126/Science.3130660  0.412
1988 Kadonaga JT, Courey AJ, Ladika J, Tjian R. Distinct regions of Sp1 modulate DNA binding and transcriptional activation. Science (New York, N.Y.). 242: 1566-70. PMID 3059495 DOI: 10.1126/Science.3059495  0.844
1988 Biggin MD, Tjian R. Transcription factors that activate the Ultrabithorax promoter in developmentally staged extracts. Cell. 53: 699-711. PMID 2897243 DOI: 10.1016/0092-8674(88)90088-8  0.799
1988 Bray SJ, Johnson WA, Hirsh J, Heberlein U, Tjian R. A cis-acting element and associated binding factor required for CNS expression of the Drosophila melanogaster dopa decarboxylase gene. The Embo Journal. 7: 177-88. PMID 2834202 DOI: 10.1002/J.1460-2075.1988.Tb02798.X  0.644
1988 Mermod N, Williams TJ, Tjian R. Enhancer binding factors AP-4 and AP-1 act in concert to activate SV40 late transcription in vitro. Nature. 332: 557-61. PMID 2833704 DOI: 10.1038/332557A0  0.546
1988 Bohmann D, Bos TJ, Admon A, Nishimura T, Vogt PK, Tjian R. Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1. Science (New York, N.Y.). 238: 1386-92. PMID 2825349 DOI: 10.1126/Science.2825349  0.457
1987 Morgan WD, Williams GT, Morimoto RI, Greene J, Kingston RE, Tjian R. Two transcriptional activators, CCAAT-box-binding transcription factor and heat shock transcription factor, interact with a human hsp70 gene promoter. Molecular and Cellular Biology. 7: 1129-38. PMID 3561411 DOI: 10.1128/mcb.7.3.1129-1138.1987  0.432
1987 Kadonaga JT, Carner KR, Masiarz FR, Tjian R. Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain. Cell. 51: 1079-90. PMID 3319186 DOI: 10.1016/0092-8674(87)90594-0  0.752
1987 Mitchell PJ, Wang C, Tjian R. Positive and negative regulation of transcription in vitro: enhancer-binding protein AP-2 is inhibited by SV40 T antigen. Cell. 50: 847-61. PMID 3040262 DOI: 10.1016/0092-8674(87)90512-5  0.47
1987 Lee W, Mitchell P, Tjian R. Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements. Cell. 49: 741-52. PMID 3034433 DOI: 10.1016/0092-8674(87)90612-X  0.512
1987 Lee W, Haslinger A, Karin M, Tjian R. Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40. Nature. 325: 368-72. PMID 3027570 DOI: 10.1038/325368A0  0.512
1987 Jones KA, Kadonaga JT, Rosenfeld PJ, Kelly TJ, Tjian R. A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication. Cell. 48: 79-89. PMID 3024847 DOI: 10.1016/0092-8674(87)90358-8  0.775
1987 Mansour SL, Grodzicker T, Tjian R. Downstream sequences affect transcription initiation from the adenovirus major late promoter. Molecular and Cellular Biology. 6: 2684-94. PMID 3023944 DOI: 10.1128/Mcb.6.7.2684  0.442
1986 Dynan WS, Sazer S, Tjian R, Schimke RT. Transcription factor Sp1 recognizes a DNA sequence in the mouse dihydrofolate reductase promoter. Nature. 319: 246-8. PMID 3945313 DOI: 10.1038/319246A0  0.521
1986 Haltiner MM, Smale ST, Tjian R. Two distinct promoter elements in the human rRNA gene identified by linker scanning mutagenesis. Molecular and Cellular Biology. 6: 227-35. PMID 3785147 DOI: 10.1128/Mcb.6.1.227  0.676
1986 Learned RM, Learned TK, Haltiner MM, Tjian RT. Human rRNA transcription is modulated by the coordinate binding of two factors to an upstream control element. Cell. 45: 847-57. PMID 3708692 DOI: 10.1016/0092-8674(86)90559-3  0.471
1986 McKnight S, Tjian R. Transcriptional selectivity of viral genes in mammalian cells. Cell. 46: 795-805. PMID 3530495 DOI: 10.1016/0092-8674(86)90061-9  0.325
1986 Briggs MR, Kadonaga JT, Bell SP, Tjian R. Purification and biochemical characterization of the promoter-specific transcription factor, Sp1. Science (New York, N.Y.). 234: 47-52. PMID 3529394 DOI: 10.1126/Science.3529394  0.823
1986 Kadonaga JT, Tjian R. Affinity purification of sequence-specific DNA binding proteins. Proceedings of the National Academy of Sciences of the United States of America. 83: 5889-93. PMID 3461465 DOI: 10.1073/Pnas.83.16.5889  0.744
1986 Smale ST, Tjian R. T-antigen-DNA polymerase alpha complex implicated in simian virus 40 DNA replication. Molecular and Cellular Biology. 6: 4077-87. PMID 3025630  0.53
1986 Ishii S, Kadonaga JT, Tjian R, Brady JN, Merlino GT, Pastan I. Binding of the Sp1 transcription factor by the human Harvey ras1 proto-oncogene promoter. Science (New York, N.Y.). 232: 1410-3. PMID 3012774 DOI: 10.1126/Science.3012774  0.79
1986 Jones KA, Kadonaga JT, Luciw PA, Tjian R. Activation of the AIDS retrovirus promoter by the cellular transcription factor, Sp1. Science (New York, N.Y.). 232: 755-9. PMID 3008338 DOI: 10.1126/Science.3008338  0.803
1986 Kadonaga JT, Jones KA, Tjian R. Promoter-specific activation of RNA polymerase II transcription by Sp1 Trends in Biochemical Sciences. 11: 20-23. DOI: 10.1016/0968-0004(86)90226-4  0.786
1985 Hauser CA, Joyner AL, Klein RD, Learned TK, Martin GR, Tjian R. Expression of homologous homeo-box-containing genes in differentiated human teratocarcinoma cells and mouse embryos. Cell. 43: 19-28. PMID 4075393 DOI: 10.1016/0092-8674(85)90008-X  0.388
1985 Dynan WS, Tjian R. Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins Nature. 316: 774-778. PMID 4041012 DOI: 10.1038/316774A0  0.544
1985 Learned RM, Cordes S, Tjian R. Purification and characterization of a transcription factor that confers promoter specificity to human RNA polymerase I. Molecular and Cellular Biology. 5: 1358-69. PMID 3929071 DOI: 10.1128/Mcb.5.6.1358  0.516
1985 Joyner AL, Lebo RV, Kan YW, Tjian R, Cox DR, Martin GR. Comparative chromosome mapping of a conserved homoeo box region in mouse and human. Nature. 314: 173-5. PMID 3919316 DOI: 10.1038/314173A0  0.339
1985 Heberlein U, England B, Tjian R. Characterization of Drosophila transcription factors that activate the tandem promoters of the alcohol dehydrogenase gene. Cell. 41: 965-77. PMID 3159479 DOI: 10.1016/S0092-8674(85)80077-5  0.756
1985 Joyner A, Hauser C, Kornberg T, Tjian R, Martin G. Structure and expression of two classes of mammalian homeo-box-containing genes. Cold Spring Harbor Symposia On Quantitative Biology. 50: 291-300. PMID 3006990 DOI: 10.1101/Sqb.1985.050.01.037  0.32
1985 Gidoni D, Kadonaga JT, Barrera-Saldaña H, Takahashi K, Chambon P, Tjian R. Bidirectional SV40 transcription mediated by tandem Sp1 binding interactions. Science (New York, N.Y.). 230: 511-7. PMID 2996137 DOI: 10.1126/Science.2996137  0.786
1985 Jones KA, Tjian R. Sp1 binds to promoter sequences and activates herpes simplex virus 'immediate-early' gene transcription in vitro Nature. 317: 179-182. PMID 2993923 DOI: 10.1038/317179A0  0.514
1985 Jones KA, Yamamoto KR, Tjian R. Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro Cell. 42: 559-572. PMID 2992804 DOI: 10.1016/0092-8674(85)90113-8  0.56
1985 Dynan WS, Saffer JD, Lee WS, Tjian R. Transcription factor Sp1 recognizes promoter sequences from the monkey genome that are similar to the simian virus 40 promoter Proceedings of the National Academy of Sciences of the United States of America. 82: 4915-4919. PMID 2991898 DOI: 10.1073/pnas.82.15.4915  0.325
1985 Mansour SL, Grodzicker T, Tjian R. An adenovirus vector system used to express polyoma virus tumor antigens. Proceedings of the National Academy of Sciences of the United States of America. 82: 1359-63. PMID 2983341 DOI: 10.1073/Pnas.82.5.1359  0.347
1985 Smale ST, Tjian R. Transcription of herpes simplex virus tk sequences under the control of wild-type and mutant human RNA polymerase I promoters. Molecular and Cellular Biology. 5: 352-62. PMID 2983190  0.645
1985 Rio DC, Clark SG, Tjian R. A mammalian host-vector system that regulates expression and amplification of transfected genes by temperature induction Science. 227: 23-28. PMID 2981116 DOI: 10.1126/Science.2981116  0.369
1984 Jones KA, Tjian R. Essential contact residues within SV40 large T antigen binding sites I and II identified by alkylation-interference Cell. 36: 155-162. PMID 6319005 DOI: 10.1016/0092-8674(84)90084-9  0.358
1984 Fisher EF, Feist PL, Beaucage SL, Meyers RM, Tjian R, Caruthers MH. Interaction of AD2+D2 protein and simian virus 40 large T antigen with the large tumor antigen binding site I. Biochemistry. 23: 5938-44. PMID 6098305 DOI: 10.1021/Bi00320A008  0.394
1984 Gidoni D, Dynan WS, Tjian R. Multiple specific contacts between a mammalian transcription factor and its cognate promoters Nature. 312: 409-413. PMID 6095100 DOI: 10.1038/312409A0  0.518
1984 Levine M, Rubin GM, Tjian R. Human DNA sequences homologous to a protein coding region conserved between homeotic genes of Drosophila. Cell. 38: 667-73. PMID 6091895 DOI: 10.1016/0092-8674(84)90261-7  0.538
1984 Jones K, Myers R, Tjian R. Mutational analysis of simian virus 40 large T antigen DNA binding sites. The Embo Journal. 3: 3247-3255. DOI: 10.1002/J.1460-2075.1984.Tb02286.X  0.364
1983 Dynan WS, Tjian R. The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter Cell. 35: 79-87. PMID 6313230 DOI: 10.1016/0092-8674(83)90210-6  0.432
1983 Thummel C, Tjian R, Hu SL, Grodzicker T. Translational control of SV40 T antigen expressed from the adenovirus late promoter. Cell. 33: 455-64. PMID 6305512 DOI: 10.1016/0092-8674(83)90427-0  0.64
1983 Learned RM, Smale ST, Haltiner MM, Tjian R. Regulation of human ribosomal RNA transcription. Proceedings of the National Academy of Sciences of the United States of America. 80: 3558-62. PMID 6304717 DOI: 10.1073/Pnas.80.12.3558  0.689
1983 Rio DC, Tjian R. SV40 T antigen binding site mutations that affect autoregulation Cell. 32: 1227-1240. PMID 6301686 DOI: 10.1016/0092-8674(83)90305-7  0.411
1983 Dynan WS, Tjian R. Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II Cell. 32: 669-680. PMID 6187469 DOI: 10.1016/0092-8674(83)90053-3  0.445
1982 Tjian R. T antigen binding and the control of SV40 gene expression. Cell. 26: 1-2. PMID 6276006 DOI: 10.1016/0092-8674(81)90026-X  0.332
1982 Myers RM, Williams RC, Tjian R. Oligomeric structure of a simian virus 40 T antigen in free form and bound to DNA. Journal of Molecular Biology. 148: 347-53. PMID 6273580 DOI: 10.1016/0022-2836(81)90180-7  0.327
1982 Dynan W, Tjian R. Transcription enhancer sequences: a novel regulatory element Trends in Biochemical Sciences. 7: 124-125. DOI: 10.1016/0968-0004(82)90196-7  0.309
1981 Thummel C, Tjian R, Grodzicker T. Expression of SV40 T antigen under control of adenovirus promoters. Cell. 23: 825-36. PMID 7226231 DOI: 10.1016/0092-8674(81)90447-5  0.638
1981 Myers RM, Rio DC, Robbins AK, Tjian R. SV40 gene expression is modulated by the cooperative binding of T antigen to DNA Cell. 25: 373-384. PMID 6269743 DOI: 10.1016/0092-8674(81)90056-8  0.454
1981 McCormick F, Clark R, Harlow E, Tjian R. SV40 T antigen binds specifically to a cellular 53 K protein in vitro. Nature. 292: 63-5. PMID 6268984 DOI: 10.1038/292063A0  0.485
1981 Thummel CS, Burgess TL, Tjian R. Properties of simian virus 40 small t antigen overproduced in bacteria. Journal of Virology. 37: 683-97. PMID 6261013 DOI: 10.1128/Jvi.37.2.683-697.1981  0.589
1981 Myers RM, Tjian R. Construction and analysis of simian virus 40 origins defective in tumor antigen binding and DNA replication. Proceedings of the National Academy of Sciences of the United States of America. 77: 6491-5. PMID 6256739 DOI: 10.1073/Pnas.77.11.6491  0.545
1981 Rio D, Robbins A, Myers R, Tjian R. Regulation of simian virus 40 early transcription in vitro by a purified tumor antigen. Proceedings of the National Academy of Sciences of the United States of America. 77: 5706-10. PMID 6255460 DOI: 10.1073/Pnas.77.10.5706  0.643
1977 Tjian R, Losick R, Pero J, Hinnebush A. Purification and comparative properties of the delta and sigma subunits of RNA polymerase from Bacillus subtilis. European Journal of Biochemistry. 74: 149-54. PMID 404142 DOI: 10.1111/J.1432-1033.1977.Tb11376.X  0.564
1975 Segall J, Tjian R, Pero J, Losick R. Chloramphenicol restores sigma factor activity to sporulating Bacillus subtilis. Proceedings of the National Academy of Sciences of the United States of America. 71: 4860-3. PMID 4216024 DOI: 10.1073/Pnas.71.12.4860  0.593
1975 Pero J, Tjian R, Nelson J, Losick R. In vitro transcription of a late class of phage SP01 genes. Nature. 257: 248-51. PMID 808738 DOI: 10.1038/257248A0  0.563
1975 Tjian R, Stinchcomb D, Losick R. Antibody directed against Bacillus subtilis rho factor purified by sodium dodecyl sulfate slab gel electrophoresis. Effect on transcription by RNA polymerase in crude extracts of vegetative and sporulating cells. Journal of Biological Chemistry. 250: 8824-8828. DOI: 10.1016/s0021-9258(19)40747-3  0.521
1974 Tjian R, Losick R. An immunological assay for the sigma subunit of RNA polymerase in extracts of vegetative and sporulating Bacillus subtilis. Proceedings of the National Academy of Sciences of the United States of America. 71: 2872-6. PMID 4211798 DOI: 10.1073/Pnas.71.7.2872  0.549
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