Jason W. Rosch, Ph.D. - Publications

Affiliations: 
2006 Washington University, Saint Louis, St. Louis, MO 
Area:
Microbiology Biology

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Smith AP, Lane LC, van Opijnen T, Woolard S, Carter R, Iverson A, Burnham C, Vogel P, Roeber D, Hochu G, Johnson MDL, McCullers JA, Rosch J, Smith AM. Dynamic pneumococcal genetic adaptations support bacterial growth and inflammation during coinfection with influenza. Infection and Immunity. PMID 33875471 DOI: 10.1128/IAI.00023-21  0.337
2021 Green AE, Howarth D, Chaguza C, Echlin H, Langendonk RF, Munro C, Barton TE, Cd Hinton J, Bentley SD, Rosch JW, Neill DR. Pneumococcal colonisation and virulence factors identified via experimental evolution in infection models. Molecular Biology and Evolution. PMID 33502519 DOI: 10.1093/molbev/msab018  0.354
2020 Echlin H, Rosch JW. Advancing Genetic Tools in . Genes. 11. PMID 32825523 DOI: 10.3390/Genes11090965  0.319
2020 Dao TH, Alsallaq R, Parsons J, Ferrolino J, Hayden RT, Rubnitz JE, Rafiqullah IM, Robinson DA, Margolis EB, Rosch JW, Wolf J. Vancomycin Heteroresistance and Clinical Outcomes in Coagulase-Negative Staphylococcal Bloodstream Infections. Antimicrobial Agents and Chemotherapy. PMID 32816729 DOI: 10.1128/Aac.00944-20  0.343
2020 Nishimoto AT, Rosch JW, Tuomanen EI. Pneumolysin: Pathogenesis and Therapeutic Target. Frontiers in Microbiology. 11: 1543. PMID 32714314 DOI: 10.3389/Fmicb.2020.01543  0.371
2020 Burcham LR, Hill RA, Caulkins RC, Emerson JP, Nanduri B, Rosch JW, Fitzkee NC, Thornton JA. Streptococcus pneumoniae metal homeostasis alters cellular metabolism. Metallomics : Integrated Biometal Science. PMID 32676626 DOI: 10.1039/D0Mt00118J  0.374
2020 Echlin H, Frank M, Rock C, Rosch JW. Role of the pyruvate metabolic network on carbohydrate metabolism and virulence in Streptococcus pneumoniae. Molecular Microbiology. PMID 32495474 DOI: 10.1111/Mmi.14557  0.334
2020 Frank MW, Yao J, Batte JL, Gullett JM, Subramanian C, Rosch JW, Rock CO. Host Fatty Acid Utilization by Staphylococcus aureus at the Infection Site. Mbio. 11. PMID 32430471 DOI: 10.1128/Mbio.00920-20  0.367
2020 Cooper VS, Honsa E, Rowe H, Deitrick C, Iverson AR, Whittall JJ, Neville SL, McDevitt CA, Kietzman C, Rosch JW. Experimental Evolution To Identify Selective Pressures during Pneumococcal Colonization. Msystems. 5. PMID 32398278 DOI: 10.1128/mSystems.00352-20  0.676
2020 Chilambi GS, Nordstrom HR, Evans DR, Ferrolino JA, Hayden RT, Marón GM, Vo AN, Gilmore MS, Wolf J, Rosch JW, Van Tyne D. Evolution of vancomycin-resistant during colonization and infection in immunocompromised pediatric patients. Proceedings of the National Academy of Sciences of the United States of America. PMID 32393645 DOI: 10.1073/Pnas.1917130117  0.391
2020 Cortez V, Boyd DF, Crawford JC, Sharp B, Livingston B, Rowe HM, Davis A, Alsallaq R, Robinson CG, Vogel P, Rosch JW, Margolis E, Thomas PG, Schultz-Cherry S. Astrovirus infects actively secreting goblet cells and alters the gut mucus barrier. Nature Communications. 11: 2097. PMID 32350281 DOI: 10.1038/S41467-020-15999-Y  0.424
2019 LeMessurier KS, Iverson AR, Chang TC, Palipane M, Vogel P, Rosch JW, Samarasinghe AE. Allergic inflammation alters the lung microbiome and hinders synergistic co-infection with H1N1 influenza virus and Streptococcus pneumoniae in C57BL/6 mice. Scientific Reports. 9: 19360. PMID 31852944 DOI: 10.1038/S41598-019-55712-8  0.374
2019 Rowe HM, Rosch JW. Close Encounters of the Viral Kind: Cross-Kingdom Synergies at the Host-Pathogen Interface. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e1900128. PMID 31693223 DOI: 10.1002/Bies.201900128  0.404
2019 Burcham ZM, Cowick CA, Baugher CN, Pechal JL, Schmidt CJ, Rosch JW, Benbow ME, Jordan HR. Total RNA Analysis of Bacterial Community Structural and Functional Shifts Throughout Vertebrate Decomposition. Journal of Forensic Sciences. PMID 31170333 DOI: 10.1111/1556-4029.14083  0.324
2019 Rowe HM, Karlsson E, Echlin H, Chang TC, Wang L, van Opijnen T, Pounds SB, Schultz-Cherry S, Rosch JW. Bacterial Factors Required for Transmission of Streptococcus pneumoniae in Mammalian Hosts. Cell Host & Microbe. PMID 31126758 DOI: 10.1016/J.Chom.2019.04.012  0.404
2019 Rowe HM, Meliopoulos VA, Iverson A, Bomme P, Schultz-Cherry S, Rosch JW. Direct interactions with influenza promote bacterial adherence during respiratory infections. Nature Microbiology. PMID 31110359 DOI: 10.1038/S41564-019-0447-0  0.376
2019 Burcham ZM, Pechal JL, Schmidt CJ, Bose JL, Rosch JW, Benbow ME, Jordan HR. Bacterial Community Succession, Transmigration, and Differential Gene Transcription in a Controlled Vertebrate Decomposition Model. Frontiers in Microbiology. 10: 745. PMID 31057499 DOI: 10.3389/Fmicb.2019.00745  0.371
2019 Burcham ZM, Schmidt CJ, Pechal JL, Brooks CP, Rosch JW, Benbow ME, Jordan HR. Detection of critical antibiotic resistance genes through routine microbiome surveillance. Plos One. 14: e0213280. PMID 30870464 DOI: 10.1371/Journal.Pone.0213280  0.345
2019 Iverson A, Meyer CJ, Vogel P, Waidyarachchi S, Das N, Bruhn DF, Poole A, Butler MM, Bowlin TL, Lee RE, Rosch JW. The Efficacy of Aminomethyl Spectinomycins against Complex Upper Respiratory Tract Bacterial Infections. Antimicrobial Agents and Chemotherapy. PMID 30858215 DOI: 10.1128/Aac.02096-18  0.379
2018 Warrier I, Ram-Mohan N, Zhu Z, Hazery A, Echlin H, Rosch J, Meyer MM, van Opijnen T. The Transcriptional landscape of Streptococcus pneumoniae TIGR4 reveals a complex operon architecture and abundant riboregulation critical for growth and virulence. Plos Pathogens. 14: e1007461. PMID 30517198 DOI: 10.1371/Journal.Ppat.1007461  0.339
2018 Margolis E, Rosch JW. Fitness Landscape of the Immune Compromised Favors the Emergence of Antibiotic Resistance. Acs Infectious Diseases. PMID 30070470 DOI: 10.1021/Acsinfecdis.8B00158  0.362
2018 Karlsson EA, Schultz-Cherry S, Rosch JW. Protective Capacity of Statins during Pneumonia Is Dependent on Etiological Agent and Obesity. Frontiers in Cellular and Infection Microbiology. 8: 41. PMID 29497602 DOI: 10.3389/Fcimb.2018.00041  0.312
2018 Dao T, Parsons J, Hayden R, Rubnitz J, Wolf J, Rosch J. 713. Vancomycin Heteroresistance in Coagulase Negative Staphylococci (CoNS) Causing Central Line-Associated Bloodstream Infection (CLABSI) in Pediatric Patients with Leukemia Open Forum Infectious Diseases. 5. DOI: 10.1093/Ofid/Ofy210.720  0.305
2017 Chang T, Rosch JW, Gu Z, Hakim H, Hewitt C, Gaur A, Wu G, Hayden RT. Whole Genome Characterization of Bacillus cereus Associated with Specific Disease Manifestations. Infection and Immunity. PMID 29158433 DOI: 10.1128/Iai.00574-17  0.38
2017 Karlsson EA, Meliopoulos VA, van de Velde NC, van de Velde LA, Mann B, Gao G, Rosch J, Tuomanen E, McCullers J, Vogel P, Schultz-Cherry S. A Perfect Storm: Increased Colonization and Failure of Vaccination Leads to Severe Secondary Bacterial Infection in Influenza Virus-Infected Obese Mice. Mbio. 8. PMID 28928207 DOI: 10.1128/Mbio.00889-17  0.338
2017 Gratz N, Loh LN, Mann B, Gao G, Carter R, Rosch J, Tuomanen EI. Pneumococcal neuraminidase activates TGF-β signalling. Microbiology (Reading, England). PMID 28749326 DOI: 10.1099/Mic.0.000511  0.327
2017 Brown LR, Caulkins RC, Schartel TE, Rosch JW, Honsa ES, Schultz-Cherry S, Meliopoulos VA, Cherry S, Thornton JA. Increased Zinc Availability Enhances Initial Aggregation and Biofilm Formation of Streptococcus pneumoniae. Frontiers in Cellular and Infection Microbiology. 7: 233. PMID 28638805 DOI: 10.3389/Fcimb.2017.00233  0.392
2017 Kadam A, Eutsey RA, Rosch J, Miao X, Longwell M, Xu W, Woolford CA, Hillman T, Motib AS, Yesilkaya H, Mitchell AP, Hiller NL. Promiscuous signaling by a regulatory system unique to the pandemic PMEN1 pneumococcal lineage. Plos Pathogens. 13: e1006339. PMID 28542565 DOI: 10.1371/Journal.Ppat.1006339  0.344
2017 Karlsson EA, Oguin TH, Meliopoulos V, Iverson A, Broadnax A, Yoon SW, Pestina T, Thomas P, Webby R, Schultz-Cherry S, Rosch JW. Vascular Permeability Drives Susceptibility to Influenza Infection in a Murine Model of Sickle Cell Disease. Scientific Reports. 7: 43308. PMID 28256526 DOI: 10.1038/Srep43308  0.356
2017 Honsa ES, Cooper VS, Mhaissen MN, Frank M, Shaker J, Iverson A, Rubnitz J, Hayden RT, Lee RE, Rock CO, Tuomanen EI, Wolf J, Rosch JW. RelA Mutant Enterococcus faecium with Multiantibiotic Tolerance Arising in an Immunocompromised Host. Mbio. 8. PMID 28049149 DOI: 10.1128/Mbio.02124-16  0.428
2016 Bryant JC, Dabbs RC, Oswalt KL, Brown LR, Rosch JW, Seo KS, Donaldson JR, McDaniel LS, Thornton JA. Pyruvate oxidase of Streptococcus pneumoniae contributes to pneumolysin release. Bmc Microbiology. 16: 271. PMID 27829373 DOI: 10.1186/S12866-016-0881-6  0.316
2016 Echlin H, Frank MW, Iverson A, Chang TC, Johnson MD, Rock CO, Rosch JW. Pyruvate Oxidase as a Critical Link between Metabolism and Capsule Biosynthesis in Streptococcus pneumoniae. Plos Pathogens. 12: e1005951. PMID 27760231 DOI: 10.1371/Journal.Ppat.1005951  0.511
2016 Meliopoulos VA, Van de Velde LA, Van de Velde NC, Karlsson EA, Neale G, Vogel P, Guy C, Sharma S, Duan S, Surman SL, Jones BG, Johnson MD, Bosio C, Jolly L, Jenkins RG, ... ... Rosch JW, et al. An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens. Plos Pathogens. 12: e1005804. PMID 27505057 DOI: 10.1371/Journal.Ppat.1005804  0.488
2016 Yao J, Carter RA, Vuagniaux G, Barbier M, Rosch JW, Rock CO. A Pathogen-Selective Antibiotic Minimizes Disturbance to the Microbiome. Antimicrobial Agents and Chemotherapy. PMID 27161626 DOI: 10.1128/Aac.00535-16  0.358
2016 Brown LR, Gunnell SM, Cassella AN, Keller LE, Scherkenbach LA, Mann B, Brown MW, Hill R, Fitzkee NC, Rosch JW, Tuomanen EI, Thornton JA. AdcAII of Streptococcus pneumoniae Affects Pneumococcal Invasiveness. Plos One. 11: e0146785. PMID 26752283 DOI: 10.1371/Journal.Pone.0146785  0.378
2015 Johnson MD, Echlin H, Dao TH, Rosch JW. Characterization of NAD Salvage Pathways and their Role in Virulence in Streptococcus pneumoniae. Microbiology (Reading, England). PMID 26311256 DOI: 10.1099/Mic.0.000164  0.577
2015 Bruhn DF, Waidyarachchi SL, Madhura DB, Shcherbakov D, Zheng Z, Liu J, Abdelrahman YM, Singh AP, Duscha S, Rathi C, Lee RB, Belland RJ, Meibohm B, Rosch JW, Böttger EC, et al. Aminomethyl spectinomycins as therapeutics for drug-resistant respiratory tract and sexually transmitted bacterial infections. Science Translational Medicine. 7: 288ra75. PMID 25995221 DOI: 10.1126/Scitranslmed.3010572  0.358
2015 Johnson MD, Kehl-Fie TE, Rosch JW. Copper intoxication inhibits aerobic nucleotide synthesis in Streptococcus pneumoniae. Metallomics : Integrated Biometal Science. 7: 786-94. PMID 25730343 DOI: 10.1039/C5Mt00011D  0.508
2015 Johnson MD, Kehl-Fie TE, Klein R, Kelly J, Burnham C, Mann B, Rosch JW. Role of copper efflux in pneumococcal pathogenesis and resistance to macrophage-mediated immune clearance. Infection and Immunity. 83: 1684-94. PMID 25667262 DOI: 10.1128/Iai.03015-14  0.553
2015 Mina MJ, Klugman KP, Rosch JW, McCullers JA. Live attenuated influenza virus increases pneumococcal translocation and persistence within the middle ear. The Journal of Infectious Diseases. 212: 195-201. PMID 25505300 DOI: 10.1093/Infdis/Jiu804  0.363
2014 Valentino MD, McGuire AM, Rosch JW, Bispo PJ, Burnham C, Sanfilippo CM, Carter RA, Zegans ME, Beall B, Earl AM, Tuomanen EI, Morris TW, Haas W, Gilmore MS. Unencapsulated Streptococcus pneumoniae from conjunctivitis encode variant traits and belong to a distinct phylogenetic cluster. Nature Communications. 5: 5411. PMID 25388376 DOI: 10.1038/Ncomms6411  0.334
2014 Carter R, Wolf J, van Opijnen T, Muller M, Obert C, Burnham C, Mann B, Li Y, Hayden RT, Pestina T, Persons D, Camilli A, Flynn PM, Tuomanen EI, Rosch JW. Genomic analyses of pneumococci from children with sickle cell disease expose host-specific bacterial adaptations and deficits in current interventions. Cell Host & Microbe. 15: 587-99. PMID 24832453 DOI: 10.1016/J.Chom.2014.04.005  0.394
2013 Honsa ES, Johnson MD, Rosch JW. The roles of transition metals in the physiology and pathogenesis of Streptococcus pneumoniae. Frontiers in Cellular and Infection Microbiology. 3: 92. PMID 24364001 DOI: 10.3389/Fcimb.2013.00092  0.521
2013 Parsons JB, Frank MW, Rosch JW, Rock CO. Staphylococcus aureus fatty acid auxotrophs do not proliferate in mice. Antimicrobial Agents and Chemotherapy. 57: 5729-32. PMID 23979734 DOI: 10.1128/Aac.01038-13  0.304
2012 Mann B, van Opijnen T, Wang J, Obert C, Wang YD, Carter R, McGoldrick DJ, Ridout G, Camilli A, Tuomanen EI, Rosch JW. Control of virulence by small RNAs in Streptococcus pneumoniae. Plos Pathogens. 8: e1002788. PMID 22807675 DOI: 10.1371/Journal.Ppat.1002788  0.361
2012 Lebensburger JD, Howard T, Hu Y, Pestina TI, Gao G, Johnson M, Zakharenko SS, Ware RE, Tuomanen EI, Persons DA, Rosch JW. Hydroxyurea therapy of a murine model of sickle cell anemia inhibits the progression of pneumococcal disease by down-modulating E-selectin. Blood. 119: 1915-21. PMID 22130804 DOI: 10.1182/Blood-2011-08-374447  0.33
2010 Rosch JW, Boyd AR, Hinojosa E, Pestina T, Hu Y, Persons DA, Orihuela CJ, Tuomanen EI. Statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease. The Journal of Clinical Investigation. 120: 627-35. PMID 20093777 DOI: 10.1172/Jci39843  0.389
2009 Kline KA, Kau AL, Chen SL, Lim A, Pinkner JS, Rosch J, Nallapareddy SR, Murray BE, Henriques-Normark B, Beatty W, Caparon MG, Hultgren SJ. Mechanism for sortase localization and the role of sortase localization in efficient pilus assembly in Enterococcus faecalis. Journal of Bacteriology. 191: 3237-47. PMID 19286802 DOI: 10.1128/Jb.01837-08  0.562
2009 Rosch JW, Gao G, Ridout G, Wang YD, Tuomanen EI. Role of the manganese efflux system mntE for signalling and pathogenesis in Streptococcus pneumoniae. Molecular Microbiology. 72: 12-25. PMID 19226324 DOI: 10.1111/J.1365-2958.2009.06638.X  0.445
2008 Rosch JW, Sublett J, Gao G, Wang YD, Tuomanen EI. Calcium efflux is essential for bacterial survival in the eukaryotic host. Molecular Microbiology. 70: 435-44. PMID 18761687 DOI: 10.1111/J.1365-2958.2008.06425.X  0.33
2008 Rosch JW, Mann B, Thornton J, Sublett J, Tuomanen E. Convergence of regulatory networks on the pilus locus of Streptococcus pneumoniae. Infection and Immunity. 76: 3187-96. PMID 18443093 DOI: 10.1128/Iai.00054-08  0.35
2008 Rosch JW, Vega LA, Beyer JM, Lin A, Caparon MG. The signal recognition particle pathway is required for virulence in Streptococcus pyogenes. Infection and Immunity. 76: 2612-9. PMID 18411293 DOI: 10.1128/Iai.00239-07  0.69
2007 Rosch JW, Tuomanen E. Adapting a diet from sugar to meat: double-dealing genes of Streptococcus pyogenes. Molecular Microbiology. 64: 257-9. PMID 17493119 DOI: 10.1111/J.1365-2958.2007.05667.X  0.342
2007 Rosch JW, Hsu FF, Caparon MG. Anionic lipids enriched at the ExPortal of Streptococcus pyogenes. Journal of Bacteriology. 189: 801-6. PMID 17142392 DOI: 10.1128/Jb.01549-06  0.522
2005 Rosch JW, Caparon MG. The ExPortal: an organelle dedicated to the biogenesis of secreted proteins in Streptococcus pyogenes. Molecular Microbiology. 58: 959-68. PMID 16262783 DOI: 10.1111/J.1365-2958.2005.04887.X  0.562
2004 Rosch J, Caparon M. A microdomain for protein secretion in Gram-positive bacteria. Science (New York, N.Y.). 304: 1513-5. PMID 15178803 DOI: 10.1126/Science.1097404  0.595
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