Zachary T. Cusumano, Ph.D. - Publications

Affiliations: 
2012 Biology & Biomedical Sciences (Biochemistry) Washington University, Saint Louis, St. Louis, MO 
Area:
Microbiology Biology, Biochemistry, Genetics

13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Klein RD, Shu Q, Cusumano ZT, Nagamatsu K, Gualberto NC, Lynch AJL, Wu C, Wang W, Jain N, Pinkner JS, Amarasinghe GK, Hultgren SJ, Frieden C, Chapman MR. Structure-Function Analysis of the Curli Accessory Protein CsgE Defines Surfaces Essential for Coordinating Amyloid Fiber Formation. Mbio. 9. PMID 30018113 DOI: 10.1128/Mbio.01349-18  0.337
2017 Xu W, Flores-Mireles AL, Cusumano ZT, Takagi E, Hultgren SJ, Caparon MG. Host and bacterial proteases influence biofilm formation and virulence in a murine model of enterococcal catheter-associated urinary tract infection. Npj Biofilms and Microbiomes. 3: 28. PMID 29134108 DOI: 10.1038/s41522-017-0036-z  0.582
2017 Spaulding CN, Klein RD, Ruer S, Kau AL, Schreiber HL, Cusumano ZT, Dodson KW, Pinkner JS, Fremont DH, Janetka JW, Remaut H, Gordon JI, Hultgren SJ. Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist. Nature. PMID 28614296 DOI: 10.1038/Nature22972  0.436
2017 Port GC, Cusumano ZT, Tumminello PR, Caparon MG. SpxA1 and SpxA2 Act Coordinately To Fine-Tune Stress Responses and Virulence in Streptococcus pyogenes. Mbio. 8. PMID 28351920 DOI: 10.1128/Mbio.00288-17  0.58
2016 Mydock-McGrane L, Cusumano Z, Han Z, Binkley J, Kostakioti M, Hannan T, Pinkner JS, Klein RD, Kalas V, Crowley J, Rath NP, Hultgren SJ, Janetka JW. Anti-virulence C-mannoisdes as antibiotic-sparing, oral therapeutics for urinary tract infections. Journal of Medicinal Chemistry. PMID 27689912 DOI: 10.1021/Acs.Jmedchem.6B00948  0.349
2016 Shu Q, Krezel AM, Cusumano ZT, Pinkner JS, Klein R, Hultgren SJ, Frieden C. Solution NMR structure of CsgE: Structural insights into a chaperone and regulator protein important for functional amyloid formation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27298344 DOI: 10.1073/Pnas.1607222113  0.361
2016 Cusumano ZT, Klein RD, Hultgren SJ. Innovative Solutions to Sticky Situations: Antiadhesive Strategies for Treating Bacterial Infections. Microbiology Spectrum. 4. PMID 27227305 DOI: 10.1128/Microbiolspec.Vmbf-0023-2015  0.449
2016 Patel MB, Garrad EC, Stavri A, Gokel MR, Negin S, Meisel JW, Cusumano Z, Gokel GW. Hydraphiles enhance antimicrobial potency against Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis. Bioorganic & Medicinal Chemistry. PMID 27166575 DOI: 10.1016/J.Bmc.2016.04.058  0.344
2016 Jarvis C, Han Z, Kalas V, Klein R, Pinkner JS, Ford B, Binkley J, Cusumano CK, Cusumano Z, Mydock-McGrane L, Hultgren SJ, Janetka JW. Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI. Chemmedchem. PMID 26812660 DOI: 10.1002/Cmdc.201600006  0.342
2015 Mydock-McGrane LK, Cusumano ZT, Janetka JW. Mannose-Derived FimH Antagonists: A promising anti-virulence therapeutic strategy for Urinary Tract Infections and Crohn's Disease. Expert Opinion On Therapeutic Patents. PMID 26651364 DOI: 10.1517/13543776.2016.1131266  0.45
2015 Cusumano ZT, Caparon MG. Citrulline protects Streptococcus pyogenes from acid stress using the arginine deiminase pathway and the F1Fo-ATPase. Journal of Bacteriology. 197: 1288-96. PMID 25645553 DOI: 10.1128/Jb.02517-14  0.587
2014 Cusumano ZT, Watson ME, Caparon MG. Streptococcus pyogenes arginine and citrulline catabolism promotes infection and modulates innate immunity. Infection and Immunity. 82: 233-42. PMID 24144727 DOI: 10.1128/Iai.00916-13  0.611
2013 Cusumano Z, Caparon M. Adaptive evolution of the Streptococcus pyogenes regulatory aldolase LacD.1. Journal of Bacteriology. 195: 1294-304. PMID 23316044 DOI: 10.1128/Jb.01997-12  0.548
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