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Jean-Pierre Changeux - Publications

Affiliations: 
Institut Pasteur, Paris, Paris, France 
Area:
Molecular Neurobiology
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Year Citation  Score
2022 Volzhenin K, Changeux JP, Dumas G. Multilevel development of cognitive abilities in an artificial neural network. Proceedings of the National Academy of Sciences of the United States of America. 119: e2201304119. PMID 36122214 DOI: 10.1073/pnas.2201304119  0.494
2021 Cecchini M, Changeux JP. Nicotinic receptors: From protein allostery to computational neuropharmacology. Molecular Aspects of Medicine. 101044. PMID 34656371 DOI: 10.1016/j.mam.2021.101044  0.319
2020 Changeux JP. Golden Anniversary of the Nicotinic Receptor. Neuron. 107: 14-16. PMID 32645305 DOI: 10.1016/j.neuron.2020.05.026  0.431
2020 Koukouli F, Changeux JP. Do Nicotinic Receptors Modulate High-Order Cognitive Processing? Trends in Neurosciences. PMID 32591156 DOI: 10.1016/j.tins.2020.06.001  0.345
2020 Changeux JP. Discovery of the First Neurotransmitter Receptor: The Acetylcholine Nicotinic Receptor. Biomolecules. 10. PMID 32260196 DOI: 10.3390/biom10040547  0.33
2020 Mashour GA, Roelfsema P, Changeux JP, Dehaene S. Conscious Processing and the Global Neuronal Workspace Hypothesis. Neuron. 105: 776-798. PMID 32135090 DOI: 10.1016/j.neuron.2020.01.026  0.54
2018 Changeux JP. The nicotinic acetylcholine receptor: a typical 'allosteric machine'. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373. PMID 29735728 DOI: 10.1098/rstb.2017.0174  0.423
2018 Changeux JP. Structural Identification of the Nicotinic Receptor Ion Channel. Trends in Neurosciences. 41: 67-70. PMID 29405928 DOI: 10.1016/j.tins.2017.11.003  0.37
2017 Martin NE, Malik S, Calimet N, Changeux JP, Cecchini M. Un-gating and allosteric modulation of a pentameric ligand-gated ion channel captured by molecular dynamics. Plos Computational Biology. 13: e1005784. PMID 29069080 DOI: 10.1371/Journal.Pcbi.1005784  0.355
2017 Changeux JP, Christopoulos A. Allosteric modulation as a unifying mechanism for receptor function and regulation. Diabetes, Obesity & Metabolism. 19: 4-21. PMID 28880476 DOI: 10.1111/dom.12959  0.412
2016 Koukouli F, Rooy M, Changeux JP, Maskos U. Nicotinic receptors in mouse prefrontal cortex modulate ultraslow fluctuations related to conscious processing. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911815 DOI: 10.1073/pnas.1614417113  0.415
2016 Edelstein SJ, Changeux JP. Biased Allostery. Biophysical Journal. 111: 902-8. PMID 27602718 DOI: 10.1016/j.bpj.2016.07.044  0.548
2016 Mathivanan S, Devesa I, Changeux JP, Ferrer-Montiel A. Bradykinin Induces TRPV1 Exocytotic Recruitment in Peptidergic Nociceptors. Frontiers in Pharmacology. 7: 178. PMID 27445816 DOI: 10.3389/Fphar.2016.00178  0.349
2015 Wieskopf JS, Mathur J, Limapichat W, Post MR, Al-Qazzaz M, Sorge RE, Martin LJ, Zaykin DV, Smith SB, Freitas K, Austin JS, Dai F, Zhang J, Marcovitz J, Tuttle AH, ... ... Changeux JP, et al. The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors. Science Translational Medicine. 7: 287ra72. PMID 25972004 DOI: 10.1126/Scitranslmed.3009986  0.737
2015 Cecchini M, Changeux JP. The nicotinic acetylcholine receptor and its prokaryotic homologues: Structure, conformational transitions & allosteric modulation. Neuropharmacology. 96: 137-49. PMID 25529272 DOI: 10.1016/J.Neuropharm.2014.12.006  0.351
2014 Changeux JP. Protein dynamics and the allosteric transitions of pentameric receptor channels. Biophysical Reviews. 6: 311-321. PMID 25505495 DOI: 10.1007/s12551-014-0149-z  0.349
2014 Devesa I, Ferrándiz-Huertas C, Mathivanan S, Wolf C, Luján R, Changeux JP, Ferrer-Montiel A. αCGRP is essential for algesic exocytotic mobilization of TRPV1 channels in peptidergic nociceptors. Proceedings of the National Academy of Sciences of the United States of America. 111: 18345-50. PMID 25489075 DOI: 10.1073/Pnas.1420252111  0.374
2014 Christopoulos A, Changeux JP, Catterall WA, Fabbro D, Burris TP, Cidlowski JA, Olsen RW, Peters JA, Neubig RR, Pin JP, Sexton PM, Kenakin TP, Ehlert FJ, Spedding M, Langmead CJ. International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric ligands. Pharmacological Reviews. 66: 918-47. PMID 25026896 DOI: 10.1124/Pr.114.008862  0.66
2014 Sauguet L, Shahsavar A, Poitevin F, Huon C, Menny A, Nemecz À, Haouz A, Changeux JP, Corringer PJ, Delarue M. Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation. Proceedings of the National Academy of Sciences of the United States of America. 111: 966-71. PMID 24367074 DOI: 10.1073/Pnas.1314997111  0.306
2013 Changeux JP. 50 years of allosteric interactions: the twists and turns of the models. Nature Reviews. Molecular Cell Biology. 14: 819-29. PMID 24150612 DOI: 10.1038/nrm3695  0.338
2013 Prevost MS, Moraga-Cid G, Van Renterghem C, Edelstein SJ, Changeux JP, Corringer PJ. Intermediate closed state for glycine receptor function revealed by cysteine cross-linking. Proceedings of the National Academy of Sciences of the United States of America. 110: 17113-8. PMID 24085847 DOI: 10.1073/Pnas.1317009110  0.625
2013 Calimet N, Simoes M, Changeux JP, Karplus M, Taly A, Cecchini M. A gating mechanism of pentameric ligand-gated ion channels. Proceedings of the National Academy of Sciences of the United States of America. 110: E3987-96. PMID 24043807 DOI: 10.1073/Pnas.1313785110  0.305
2013 Changeux JP. The concept of allosteric interaction and its consequences for the chemistry of the brain. The Journal of Biological Chemistry. 288: 26969-86. PMID 23878193 DOI: 10.1074/jbc.X113.503375  0.363
2013 Tolu S, Eddine R, Marti F, David V, Graupner M, Pons S, Baudonnat M, Husson M, Besson M, Reperant C, Zemdegs J, Pagès C, Hay YA, Lambolez B, Caboche J, ... ... Changeux JP, et al. Co-activation of VTA DA and GABA neurons mediates nicotine reinforcement. Molecular Psychiatry. 18: 382-93. PMID 22751493 DOI: 10.1038/Mp.2012.83  0.529
2012 Changeux JP. The nicotinic acetylcholine receptor: the founding father of the pentameric ligand-gated ion channel superfamily. The Journal of Biological Chemistry. 287: 40207-15. PMID 23038257 DOI: 10.1074/jbc.R112.407668  0.456
2012 Corringer PJ, Poitevin F, Prevost MS, Sauguet L, Delarue M, Changeux JP. Structure and pharmacology of pentameric receptor channels: from bacteria to brain. Structure (London, England : 1993). 20: 941-56. PMID 22681900 DOI: 10.1016/J.Str.2012.05.003  0.369
2012 Wacongne C, Changeux JP, Dehaene S. A neuronal model of predictive coding accounting for the mismatch negativity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3665-78. PMID 22423089 DOI: 10.1523/Jneurosci.5003-11.2012  0.773
2012 Changeux JP. Allostery and the Monod-Wyman-Changeux model after 50 years. Annual Review of Biophysics. 41: 103-33. PMID 22224598 DOI: 10.1146/annurev-biophys-050511-102222  0.312
2012 Besson M, David V, Baudonnat M, Cazala P, Guilloux JP, Reperant C, Cloez-Tayarani I, Changeux JP, Gardier AM, Granon S. Alpha7-nicotinic receptors modulate nicotine-induced reinforcement and extracellular dopamine outflow in the mesolimbic system in mice. Psychopharmacology. 220: 1-14. PMID 21901321 DOI: 10.1007/S00213-011-2422-1  0.431
2012 Bourgeois JP, Meas-Yeadid V, Lesourd AM, Faure P, Pons S, Maskos U, Changeux JP, Olivo-Marin JC, Granon S. Modulation of the mouse prefrontal cortex activation by neuronal nicotinic receptors during novelty exploration but not by exploration of a familiar environment. Cerebral Cortex (New York, N.Y. : 1991). 22: 1007-15. PMID 21810785 DOI: 10.1093/Cercor/Bhr159  0.545
2012 Changeux JP, Giraudat J, Heidmann T, Popot JL, Sobel A. Functional properties of the acetylcholine receptor protein. Neurochemistry International. 219-31. PMID 20487788 DOI: 10.1016/0197-0186(80)90029-7  0.38
2012 Corringer P, Nury H, Van Renterghem C, Yeng Y, Tran A, Baaden M, Changeux J, Sonner JM, Delarue M. Allosteric Transition and Pharmacological Modulation of Pentameric Channel-Receptors: The Case of General Anesthetics Biophysical Journal. 102: 7a. DOI: 10.1016/J.Bpj.2011.11.060  0.411
2011 Changeux JP, Edelstein S. Conformational selection or induced fit? 50 years of debate resolved. F1000 Biology Reports. 3: 19. PMID 21941598 DOI: 10.3410/B3-19  0.624
2011 Dehaene S, Changeux JP. Experimental and theoretical approaches to conscious processing. Neuron. 70: 200-27. PMID 21521609 DOI: 10.1016/j.neuron.2011.03.018  0.59
2011 Exley R, Maubourguet N, David V, Eddine R, Evrard A, Pons S, Marti F, Threlfell S, Cazala P, McIntosh JM, Changeux JP, Maskos U, Cragg SJ, Faure P. Distinct contributions of nicotinic acetylcholine receptor subunit alpha4 and subunit alpha6 to the reinforcing effects of nicotine. Proceedings of the National Academy of Sciences of the United States of America. 108: 7577-82. PMID 21502501 DOI: 10.1073/Pnas.1103000108  0.572
2011 Avale ME, Chabout J, Pons S, Serreau P, De Chaumont F, Olivo-Marin JC, Bourgeois JP, Maskos U, Changeux JP, Granon S. Prefrontal nicotinic receptors control novel social interaction between mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2145-55. PMID 21402717 DOI: 10.1096/Fj.10-178558  0.316
2011 Lykhmus O, Koval L, Skok M, Zouridakis M, Zisimopoulou P, Tzartos S, Tsetlin V, Granon S, Changeux JP, Komisarenko S, Cloëz-Tayarani I. Antibodies against extracellular domains of α4 and α7 subunits alter the levels of nicotinic receptors in the mouse brain and affect memory: possible relevance to Alzheimer's pathology. Journal of Alzheimer's Disease : Jad. 24: 693-704. PMID 21321393 DOI: 10.3233/Jad-2011-101842  0.34
2011 Nury H, Van Renterghem C, Weng Y, Tran A, Baaden M, Dufresne V, Changeux JP, Sonner JM, Delarue M, Corringer PJ. X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel. Nature. 469: 428-31. PMID 21248852 DOI: 10.1038/Nature09647  0.381
2011 Markram H, Meier K, Lippert T, Grillner S, Frackowiak R, Dehaene S, Knoll A, Sompolinsky H, Verstreken K, DeFelipe J, Grant S, Changeux JP, Sariam A. Introducing the Human Brain Project Procedia Computer Science. 7: 39-42. DOI: 10.1016/j.procs.2011.12.015  0.492
2011 Nury H, Poitevin F, Van Renterghem C, Allen T, Changeux J, Corringer P, Delarue M, Baaden M. Conformational Dynamics in a Nicotinic Receptor Homologue Probed by Simulations Biophysical Journal. 100: 272a. DOI: 10.1016/J.Bpj.2010.12.1695  0.322
2011 Dehaene S, Changeux JP, Naccache L. The global neuronal workspace model of conscious access: From neuronal architectures to clinical applications Research and Perspectives in Neurosciences. 18: 55-84. DOI: 10.1007/978-3-642-18015-6_4  0.652
2010 Villégier AS, Salomon L, Granon S, Champtiaux N, Changeux JP, Tassin JP. α7 and β2 nicotinic receptors control monoamine-mediated locomotor response. Neuroreport. 21: 1085-9. PMID 20890227 DOI: 10.1097/Wnr.0B013E328340536A  0.355
2010 Azam L, Maskos U, Changeux JP, Dowell CD, Christensen S, De Biasi M, McIntosh JM. α-Conotoxin BuIA[T5A;P6O]: a novel ligand that discriminates between α6ß4 and α6ß2 nicotinic acetylcholine receptors and blocks nicotine-stimulated norepinephrine release. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 5113-23. PMID 20739611 DOI: 10.1096/fj.10.166272  0.301
2010 Ballesteros-Yáñez I, Benavides-Piccione R, Bourgeois JP, Changeux JP, DeFelipe J. Alterations of cortical pyramidal neurons in mice lacking high-affinity nicotinic receptors. Proceedings of the National Academy of Sciences of the United States of America. 107: 11567-72. PMID 20534523 DOI: 10.1073/pnas.1006269107  0.412
2010 Changeux JP. Nicotine addiction and nicotinic receptors: lessons from genetically modified mice. Nature Reviews. Neuroscience. 11: 389-401. PMID 20485364 DOI: 10.1038/nrn2849  0.414
2010 Edelstein SJ, Changeux JP. Relationships between structural dynamics and functional kinetics in oligomeric membrane receptors. Biophysical Journal. 98: 2045-52. PMID 20483311 DOI: 10.1016/J.Bpj.2010.01.050  0.647
2010 Nury H, Poitevin F, Van Renterghem C, Changeux JP, Corringer PJ, Delarue M, Baaden M. One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue. Proceedings of the National Academy of Sciences of the United States of America. 107: 6275-80. PMID 20308576 DOI: 10.1073/Pnas.1001832107  0.339
2010 Changeux JP. Allosteric receptors: from electric organ to cognition. Annual Review of Pharmacology and Toxicology. 50: 1-38. PMID 20055696 DOI: 10.1146/annurev.pharmtox.010909.105741  0.462
2010 Changeux JP, Paas Y. Nicotinic Acetylcholine Receptors Encyclopedia of Neuroscience. 1129-1133. DOI: 10.1016/B978-008045046-9.01127-X  0.445
2009 Maouche K, Polette M, Jolly T, Medjber K, Cloëz-Tayarani I, Changeux JP, Burlet H, Terryn C, Coraux C, Zahm JM, Birembaut P, Tournier JM. {alpha}7 nicotinic acetylcholine receptor regulates airway epithelium differentiation by controlling basal cell proliferation. The American Journal of Pathology. 175: 1868-82. PMID 19808646 DOI: 10.2353/ajpath.2009.090212  0.358
2009 Wiklund A, Granon S, Faure P, Sundman E, Changeux JP, Eriksson LI. Object memory in young and aged mice after sevoflurane anaesthesia. Neuroreport. 20: 1419-23. PMID 19738500 DOI: 10.1097/Wnr.0B013E328330Cd2B  0.499
2009 Taly A, Corringer PJ, Guedin D, Lestage P, Changeux JP. Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system. Nature Reviews. Drug Discovery. 8: 733-50. PMID 19721446 DOI: 10.1038/nrd2927  0.446
2009 Changeux JP. Nicotinic receptors and nicotine addiction. Comptes Rendus Biologies. 332: 421-5. PMID 19393973 DOI: 10.1016/j.crvi.2009.02.005  0.419
2009 Bocquet N, Nury H, Baaden M, Le Poupon C, Changeux JP, Delarue M, Corringer PJ. X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation. Nature. 457: 111-4. PMID 18987633 DOI: 10.1038/Nature07462  0.313
2008 Maubourguet N, Lesne A, Changeux JP, Maskos U, Faure P. Behavioral sequence analysis reveals a novel role for beta2* nicotinic receptors in exploration. Plos Computational Biology. 4: e1000229. PMID 19023420 DOI: 10.1371/Journal.Pcbi.1000229  0.564
2008 Wiklund A, Granon S, Cloëz-Tayarani I, Faure P, le Sourd AM, Sundman E, Changeux JP, Eriksson LI. Sevoflurane anesthesia alters exploratory and anxiety-like behavior in mice lacking the beta2 nicotinic acetylcholine receptor subunit. Anesthesiology. 109: 790-8. PMID 18946289 DOI: 10.1097/Aln.0B013E31818A379A  0.586
2008 Avale ME, Faure P, Pons S, Robledo P, Deltheil T, David DJ, Gardier AM, Maldonado R, Granon S, Changeux JP, Maskos U. Interplay of beta2* nicotinic receptors and dopamine pathways in the control of spontaneous locomotion. Proceedings of the National Academy of Sciences of the United States of America. 105: 15991-6. PMID 18832468 DOI: 10.1073/Pnas.0807635105  0.595
2008 Even N, Cardona A, Soudant M, Corringer PJ, Changeux JP, Cloëz-Tayarani I. Regional differential effects of chronic nicotine on brain alpha 4-containing and alpha 6-containing receptors. Neuroreport. 19: 1545-50. PMID 18797314 DOI: 10.1097/WNR.0b013e3283112703  0.318
2008 Evrard A, Changeux JP. Abnormal response of dopaminergic neurons to nicotine without perturbation of nicotinic receptors in alphaCGRP knock-out mice. Brain Research. 1228: 89-96. PMID 18619948 DOI: 10.1016/j.brainres.2008.06.072  0.435
2008 Aráoz R, Herdman M, Rippka R, Ledreux A, Molgó J, Changeux JP, Tandeau de Marsac N, Nghiêm HO. A non-radioactive ligand-binding assay for detection of cyanobacterial anatoxins using Torpedo electrocyte membranes. Toxicon : Official Journal of the International Society On Toxinology. 52: 163-74. PMID 18617214 DOI: 10.1016/j.toxicon.2008.05.001  0.394
2008 Besson M, Suarez S, Cormier A, Changeux JP, Granon S. Chronic nicotine exposure has dissociable behavioural effects on control and beta2-/- mice. Behavior Genetics. 38: 503-14. PMID 18607712 DOI: 10.1007/S10519-008-9216-1  0.348
2008 Taly A, Changeux JP. Functional organization and conformational dynamics of the nicotinic receptor: a plausible structural interpretation of myasthenic mutations. Annals of the New York Academy of Sciences. 1132: 42-52. PMID 18567852 DOI: 10.1196/annals.1405.008  0.372
2008 Changeux JP, Taly A. Nicotinic receptors, allosteric proteins and medicine. Trends in Molecular Medicine. 14: 93-102. PMID 18262468 DOI: 10.1016/j.molmed.2008.01.001  0.44
2008 Jackson KJ, Martin BR, Changeux JP, Damaj MI. Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs. The Journal of Pharmacology and Experimental Therapeutics. 325: 302-12. PMID 18184829 DOI: 10.1124/Jpet.107.132977  0.308
2007 Kabbani N, Woll MP, Levenson R, Lindstrom JM, Changeux JP. Intracellular complexes of the beta2 subunit of the nicotinic acetylcholine receptor in brain identified by proteomics. Proceedings of the National Academy of Sciences of the United States of America. 104: 20570-5. PMID 18077321 DOI: 10.1073/Pnas.0710314104  0.723
2007 Zanardi A, Ferrari R, Leo G, Maskos U, Changeux JP, Zoli M. Loss of high-affinity nicotinic receptors increases the vulnerability to excitotoxic lesion and decreases the positive effects of an enriched environment. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 4028-37. PMID 17622669 DOI: 10.1096/fj.07-8260com  0.353
2007 Konstantakaki M, Changeux JP, Taly A. Docking of alpha-cobratoxin suggests a basal conformation of the nicotinic receptor. Biochemical and Biophysical Research Communications. 359: 413-8. PMID 17555709 DOI: 10.1016/j.bbrc.2007.05.126  0.44
2007 Besson M, Granon S, Mameli-Engvall M, Cloëz-Tayarani I, Maubourguet N, Cormier A, Cazala P, David V, Changeux JP, Faure P. Long-term effects of chronic nicotine exposure on brain nicotinic receptors. Proceedings of the National Academy of Sciences of the United States of America. 104: 8155-60. PMID 17470777 DOI: 10.1073/Pnas.0702698104  0.598
2007 Moser N, Mechawar N, Jones I, Gochberg-Sarver A, Orr-Urtreger A, Plomann M, Salas R, Molles B, Marubio L, Roth U, Maskos U, Winzer-Serhan U, Bourgeois JP, Le Sourd AM, De Biasi M, ... ... Changeux JP, et al. Evaluating the suitability of nicotinic acetylcholine receptor antibodies for standard immunodetection procedures. Journal of Neurochemistry. 102: 479-92. PMID 17419810 DOI: 10.1111/J.1471-4159.2007.04498.X  0.632
2007 Scholze P, Orr-Urtreger A, Changeux JP, McIntosh JM, Huck S. Catecholamine outflow from mouse and rat brain slice preparations evoked by nicotinic acetylcholine receptor activation and electrical field stimulation. British Journal of Pharmacology. 151: 414-22. PMID 17401441 DOI: 10.1038/sj.bjp.0707236  0.302
2007 Bocquet N, Prado de Carvalho L, Cartaud J, Neyton J, Le Poupon C, Taly A, Grutter T, Changeux JP, Corringer PJ. A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family. Nature. 445: 116-9. PMID 17167423 DOI: 10.1038/Nature05371  0.698
2007 Cloëz-Tayarani I, Changeux JP. Nicotine and serotonin in immune regulation and inflammatory processes: a perspective. Journal of Leukocyte Biology. 81: 599-606. PMID 17108054 DOI: 10.1189/jlb.0906544  0.363
2007 Kabbani N, Changeux JP. Proteomic Profiling of Interactions Comprising the Beta 2 Subunit of the Nicotine Receptor Using MALDI‐TOF MS Analysis The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A421-A  0.631
2006 Molles BE, Maskos U, Pons S, Besson M, Guiard P, Guilloux JP, Evrard A, Cormier A, Mameli-Engvall M, Cloëz-Tayarani I, Nakatani H, Dufour N, Bemelmans AP, Mallet J, Cazala P, ... ... Changeux JP, et al. Targeted in vivo expression of nicotinic acetylcholine receptors in mouse brain using lentiviral expression vectors. Journal of Molecular Neuroscience : Mn. 30: 105-6. PMID 17192649 DOI: 10.1385/JMN:30:1:105  0.542
2006 Grutter T, de Carvalho LP, Dufresne V, Taly A, Changeux JP. Identification of two critical residues within the Cys-loop sequence that determine fast-gating kinetics in a pentameric ligand-gated ion channel. Journal of Molecular Neuroscience : Mn. 30: 63-4. PMID 17192629 DOI: 10.1385/Jmn:30:1:63  0.733
2006 Taly A, Corringer PJ, Grutter T, Prado de Carvalho L, Karplus M, Changeux JP. Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors. Proceedings of the National Academy of Sciences of the United States of America. 103: 16965-70. PMID 17077146 DOI: 10.1073/Pnas.0607477103  0.731
2006 Changeux JP. The Ferrier Lecture 1998. The molecular biology of consciousness investigated with genetically modified mice. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 361: 2239-59. PMID 17015398 DOI: 10.1098/rstb.2006.1832  0.335
2006 Le Magueresse C, Safiulina V, Changeux JP, Cherubini E. Nicotinic modulation of network and synaptic transmission in the immature hippocampus investigated with genetically modified mice. The Journal of Physiology. 576: 533-46. PMID 16901939 DOI: 10.1113/jphysiol.2006.117572  0.815
2006 Zanetti L, de Kerchove D'Exaerde A, Zanardi A, Changeux JP, Picciotto MR, Zoli M. Inhibition of both alpha7* and beta2* nicotinic acetylcholine receptors is necessary to prevent development of sensitization to cocaine-elicited increases in extracellular dopamine levels in the ventral striatum. Psychopharmacology. 187: 181-8. PMID 16826402 DOI: 10.1007/s00213-006-0419-y  0.572
2006 Mameli-Engvall M, Evrard A, Pons S, Maskos U, Svensson TH, Changeux JP, Faure P. Hierarchical control of dopamine neuron-firing patterns by nicotinic receptors. Neuron. 50: 911-21. PMID 16772172 DOI: 10.1016/J.Neuron.2006.05.007  0.618
2006 Granon S, Changeux JP. Attention-deficit/hyperactivity disorder: a plausible mouse model? Acta Paediatrica (Oslo, Norway : 1992). 95: 645-9. PMID 16754543 DOI: 10.1080/08035250600719747  0.33
2006 Dehaene S, Changeux JP, Naccache L, Sackur J, Sergent C. Conscious, preconscious, and subliminal processing: a testable taxonomy. Trends in Cognitive Sciences. 10: 204-11. PMID 16603406 DOI: 10.1016/J.Tics.2006.03.007  0.76
2006 David V, Besson M, Changeux JP, Granon S, Cazala P. Reinforcing effects of nicotine microinjections into the ventral tegmental area of mice: dependence on cholinergic nicotinic and dopaminergic D1 receptors. Neuropharmacology. 50: 1030-40. PMID 16580026 DOI: 10.1016/J.Neuropharm.2006.02.003  0.41
2006 Sunesen M, de Carvalho LP, Dufresne V, Grailhe R, Savatier-Duclert N, Gibor G, Peretz A, Attali B, Changeux JP, Paas Y. Mechanism of Cl- selection by a glutamate-gated chloride (GluCl) receptor revealed through mutations in the selectivity filter. The Journal of Biological Chemistry. 281: 14875-81. PMID 16527818 DOI: 10.1074/jbc.M511657200  0.369
2006 Corringer PJ, Sallette J, Changeux JP. Nicotine enhances intracellular nicotinic receptor maturation: a novel mechanism of neural plasticity? Journal of Physiology, Paris. 99: 162-71. PMID 16458492 DOI: 10.1016/j.jphysparis.2005.12.012  0.436
2006 Walters CL, Brown S, Changeux JP, Martin B, Damaj MI. The beta2 but not alpha7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice. Psychopharmacology. 184: 339-44. PMID 16416156 DOI: 10.1007/S00213-005-0295-X  0.417
2006 Gutkin BS, Dehaene S, Changeux JP. A neurocomputational hypothesis for nicotine addiction. Proceedings of the National Academy of Sciences of the United States of America. 103: 1106-11. PMID 16415156 DOI: 10.1073/pnas.0510220103  0.651
2006 Villégier AS, Salomon L, Granon S, Changeux JP, Belluzzi JD, Leslie FM, Tassin JP. Monoamine oxidase inhibitors allow locomotor and rewarding responses to nicotine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1704-13. PMID 16395299 DOI: 10.1038/Sj.Npp.1300987  0.378
2006 Skok M, Grailhe R, Agenes F, Changeux JP. The role of nicotinic acetylcholine receptors in lymphocyte development. Journal of Neuroimmunology. 171: 86-98. PMID 16253349 DOI: 10.1016/j.jneuroim.2005.09.011  0.416
2006 Changeux JP, Edelstein SJ. Allosteric receptors after 30 years Rendiconti Lincei. 17: 59-96. DOI: 10.1007/BF02904502  0.575
2006 West R, Markou A, Peto R, Perkins K, Shiffman S, Clarke PBS, Walton R, Bertrand D, Brody AL, Picciotto MR, Changeux JP, Balfour D, Heidbreder C. General discussion II Novartis Foundation Symposium. 275: 197-203.  0.369
2006 Changeux JP, Markou A, Shiffman S, West R, Stolerman I, Balfour D, Picciotto MR, Walton R, Clarke PBS, Corrigall WA, Bertrand D, Brody AL. Discussion Novartis Foundation Symposium. 275: 145-152.  0.372
2006 Maskos U, Granon S, Faure P, Changeux JP. Nicotinic acetylcholine receptor functions in the CNS investigated with a novel method of stereotaxic gene re-expression in knockout mice Novartis Foundation Symposium. 275: 64-79.  0.531
2005 Grutter T, de Carvalho LP, Dufresne V, Taly A, Edelstein SJ, Changeux JP. Molecular tuning of fast gating in pentameric ligand-gated ion channels. Proceedings of the National Academy of Sciences of the United States of America. 102: 18207-12. PMID 16319224 DOI: 10.1073/Pnas.0509024102  0.794
2005 Paas Y, Gibor G, Grailhe R, Savatier-Duclert N, Dufresne V, Sunesen M, de Carvalho LP, Changeux JP, Attali B. Pore conformations and gating mechanism of a Cys-loop receptor. Proceedings of the National Academy of Sciences of the United States of America. 102: 15877-82. PMID 16247006 DOI: 10.1073/pnas.0507599102  0.38
2005 Gotti C, Moretti M, Zanardi A, Gaimarri A, Champtiaux N, Changeux JP, Whiteaker P, Marks MJ, Clementi F, Zoli M. Heterogeneity and selective targeting of neuronal nicotinic acetylcholine receptor (nAChR) subtypes expressed on retinal afferents of the superior colliculus and lateral geniculate nucleus: identification of a new native nAChR subtype alpha3beta2(alpha5 or beta3) enriched in retinocollicular afferents. Molecular Pharmacology. 68: 1162-71. PMID 16049166 DOI: 10.1124/Mol.105.015925  0.427
2005 Maskos U, Molles BE, Pons S, Besson M, Guiard BP, Guilloux JP, Evrard A, Cazala P, Cormier A, Mameli-Engvall M, Dufour N, Cloëz-Tayarani I, Bemelmans AP, Mallet J, Gardier AM, ... ... Changeux JP, et al. Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors. Nature. 436: 103-7. PMID 16001069 DOI: 10.1038/Nature03694  0.608
2005 Skok M, Grailhe R, Changeux JP. Nicotinic receptors regulate B lymphocyte activation and immune response. European Journal of Pharmacology. 517: 246-51. PMID 15963492 DOI: 10.1016/j.ejphar.2005.05.011  0.418
2005 Sallette J, Pons S, Devillers-Thiery A, Soudant M, Prado de Carvalho L, Changeux JP, Corringer PJ. Nicotine upregulates its own receptors through enhanced intracellular maturation. Neuron. 46: 595-607. PMID 15944128 DOI: 10.1016/j.neuron.2005.03.029  0.457
2005 Changeux JP, Edelstein SJ. Allosteric mechanisms of signal transduction. Science (New York, N.Y.). 308: 1424-8. PMID 15933191 DOI: 10.1126/Science.1108595  0.549
2005 Dehaene S, Changeux JP. Ongoing spontaneous activity controls access to consciousness: a neuronal model for inattentional blindness. Plos Biology. 3: e141. PMID 15819609 DOI: 10.1371/journal.pbio.0030141  0.597
2005 Grutter T, Prado de Carvalho L, Virginie D, Taly A, Fischer M, Changeux JP. A chimera encoding the fusion of an acetylcholine-binding protein to an ion channel is stabilized in a state close to the desensitized form of ligand-gated ion channels. Comptes Rendus Biologies. 328: 223-34. PMID 15810546 DOI: 10.1016/J.Crvi.2004.11.004  0.692
2005 Taly A, Delarue M, Grutter T, Nilges M, Le Novère N, Corringer PJ, Changeux JP. Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism. Biophysical Journal. 88: 3954-65. PMID 15805177 DOI: 10.1529/Biophysj.104.050229  0.714
2005 Cohen G, Roux JC, Grailhe R, Malcolm G, Changeux JP, Lagercrantz H. Perinatal exposure to nicotine causes deficits associated with a loss of nicotinic receptor function. Proceedings of the National Academy of Sciences of the United States of America. 102: 3817-21. PMID 15738419 DOI: 10.1073/Pnas.0409782102  0.422
2005 Popot J, Cartaud J, Changeux J. Reconstitution of a functional acetylcholine receptor. Incorporation into artificial lipid vesicles and pharmacology of the agonist-controlled permeability changes. Febs Journal. 118: 203-214. DOI: 10.1111/J.1432-1033.1981.Tb06388.X  0.358
2005 Changeux JP. The visit of Professor Chen-Yuan Lee to the Pasteur Institute in 1970 and the use of a snake venom toxin to identify the acetylcholine receptor protein Journal of Toxicology - Toxin Reviews. 24: 15-41. DOI: 10.1081/TXR-200046237  0.413
2005 Skok MV, Grailhe R, Agenes F, Changeux JP. Signaling through nicotinic acetylcholine receptors regulates lymphocyte development and activation Ukrain'Skyi Biokhimichnyi Zhurnal. 77: 34.  0.301
2004 Strochlic L, Cartaud A, Mejat A, Grailhe R, Schaeffer L, Changeux JP, Cartaud J. 14-3-3 gamma associates with muscle specific kinase and regulates synaptic gene transcription at vertebrate neuromuscular synapse. Proceedings of the National Academy of Sciences of the United States of America. 101: 18189-94. PMID 15604144 DOI: 10.1073/pnas.0406905102  0.318
2004 Dauger S, Durand E, Cohen G, Lagercrantz H, Changeux JP, Gaultier C, Gallego J. Control of breathing in newborn mice lacking the beta-2 nAChR subunit. Acta Physiologica Scandinavica. 182: 205-12. PMID 15450117 DOI: 10.1111/J.1365-201X.2004.01345.X  0.34
2004 Cormier A, Paas Y, Zini R, Tillement JP, Lagrue G, Changeux JP, Grailhe R. Long-term exposure to nicotine modulates the level and activity of acetylcholine receptors in white blood cells of smokers and model mice. Molecular Pharmacology. 66: 1712-8. PMID 15383622 DOI: 10.1124/mol.104.000463  0.451
2004 Maggi L, Sola E, Minneci F, Le Magueresse C, Changeux JP, Cherubini E. Persistent decrease in synaptic efficacy induced by nicotine at Schaffer collateral-CA1 synapses in the immature rat hippocampus. The Journal of Physiology. 559: 863-74. PMID 15272042 DOI: 10.1113/jphysiol.2004.067041  0.796
2004 Léna C, Popa D, Grailhe R, Escourrou P, Changeux JP, Adrien J. Beta2-containing nicotinic receptors contribute to the organization of sleep and regulate putative micro-arousals in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5711-8. PMID 15215293 DOI: 10.1523/Jneurosci.3882-03.2004  0.333
2004 Mechawar N, Saghatelyan A, Grailhe R, Scoriels L, Gheusi G, Gabellec MM, Lledo PM, Changeux JP. Nicotinic receptors regulate the survival of newborn neurons in the adult olfactory bulb. Proceedings of the National Academy of Sciences of the United States of America. 101: 9822-6. PMID 15210938 DOI: 10.1073/Pnas.0403361101  0.635
2004 Cordero-Erausquin M, Pons S, Faure P, Changeux JP. Nicotine differentially activates inhibitory and excitatory neurons in the dorsal spinal cord. Pain. 109: 308-18. PMID 15157692 DOI: 10.1016/J.Pain.2004.01.034  0.812
2004 Salmon AM, Evrard A, Damaj I, Changeux JP. Reduction of withdrawal signs after chronic nicotine exposure of alpha-calcitonin gene-related peptide knock-out mice. Neuroscience Letters. 360: 73-6. PMID 15082182 DOI: 10.1016/j.neulet.2004.02.031  0.389
2004 Grailhe R, de Carvalho LP, Paas Y, Le Poupon C, Soudant M, Bregestovski P, Changeux JP, Corringer PJ. Distinct subcellular targeting of fluorescent nicotinic alpha 3 beta 4 and serotoninergic 5-HT3A receptors in hippocampal neurons. The European Journal of Neuroscience. 19: 855-62. PMID 15009132 DOI: 10.1111/J.1460-9568.2004.03153.X  0.456
2004 Grutter T, Le Novère N, Changeux JP. Rational understanding of nicotinic receptors drug binding. Current Topics in Medicinal Chemistry. 4: 645-50. PMID 14965300 DOI: 10.2174/1568026043451177  0.745
2004 Sallette J, Bohler S, Benoit P, Soudant M, Pons S, Le Novère N, Changeux JP, Corringer PJ. An extracellular protein microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine. The Journal of Biological Chemistry. 279: 18767-75. PMID 14764595 DOI: 10.1074/jbc.M308260200  0.462
2004 Champtiaux N, Changeux JP. Knockout and knockin mice to investigate the role of nicotinic receptors in the central nervous system. Progress in Brain Research. 145: 235-51. PMID 14650919 DOI: 10.1016/S0079-6123(03)45016-4  0.429
2003 Grubb MS, Rossi FM, Changeux JP, Thompson ID. Abnormal functional organization in the dorsal lateral geniculate nucleus of mice lacking the beta 2 subunit of the nicotinic acetylcholine receptor. Neuron. 40: 1161-72. PMID 14687550 DOI: 10.1016/S0896-6273(03)00789-X  0.468
2003 Sunesen M, Huchet-Dymanus M, Christensen MO, Changeux JP. Phosphorylation-elicited quaternary changes of GA binding protein in transcriptional activation. Molecular and Cellular Biology. 23: 8008-18. PMID 14585962 DOI: 10.1128/MCB.23.22.8008-8018.2003  0.316
2003 Devillers-Thiéry A, Bourgeois JP, Pons S, Le Sourd A, Pucci B, Changeux JP. An in vitro study of the sub-cellular distribution of nicotinic receptors. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 95: 373-81. PMID 14519554 DOI: 10.1016/S0248-4900(03)00084-4  0.336
2003 Skok MV, Kalashnik EN, Koval LN, Tsetlin VI, Utkin YN, Changeux JP, Grailhe R. Functional nicotinic acetylcholine receptors are expressed in B lymphocyte-derived cell lines. Molecular Pharmacology. 64: 885-9. PMID 14500745 DOI: 10.1124/mol.64.4.885  0.421
2003 Paas Y, Cartaud J, Recouvreur M, Grailhe R, Dufresne V, Pebay-Peyroula E, Landau EM, Changeux JP. Electron microscopic evidence for nucleation and growth of 3D acetylcholine receptor microcrystals in structured lipid-detergent matrices. Proceedings of the National Academy of Sciences of the United States of America. 100: 11309-14. PMID 13679581 DOI: 10.1073/pnas.1834451100  0.382
2003 Champtiaux N, Gotti C, Cordero-Erausquin M, David DJ, Przybylski C, Léna C, Clementi F, Moretti M, Rossi FM, Le Novère N, McIntosh JM, Gardier AM, Changeux JP. Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7820-9. PMID 12944511 DOI: 10.1523/Jneurosci.23-21-07820.2003  0.809
2003 Granon S, Faure P, Changeux JP. Executive and social behaviors under nicotinic receptor regulation. Proceedings of the National Academy of Sciences of the United States of America. 100: 9596-601. PMID 12876201 DOI: 10.1073/Pnas.1533498100  0.538
2003 Dehaene S, Sergent C, Changeux JP. A neuronal network model linking subjective reports and objective physiological data during conscious perception. Proceedings of the National Academy of Sciences of the United States of America. 100: 8520-5. PMID 12829797 DOI: 10.1073/pnas.1332574100  0.726
2003 Grutter T, Prado de Carvalho L, Le Novère N, Corringer PJ, Edelstein S, Changeux JP. An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors. The Embo Journal. 22: 1990-2003. PMID 12727867 DOI: 10.1093/Emboj/Cdg197  0.792
2003 Han ZY, Zoli M, Cardona A, Bourgeois JP, Changeux JP, Le Novère N. Localization of [3H]nicotine, [3H]cytisine, [3H]epibatidine, and [125I]alpha-bungarotoxin binding sites in the brain of Macaca mulatta. The Journal of Comparative Neurology. 461: 49-60. PMID 12722104 DOI: 10.1002/cne.10659  0.364
2003 Marubio LM, Gardier AM, Durier S, David D, Klink R, Arroyo-Jimenez MM, McIntosh JM, Rossi F, Champtiaux N, Zoli M, Changeux JP. Effects of nicotine in the dopaminergic system of mice lacking the alpha4 subunit of neuronal nicotinic acetylcholine receptors. The European Journal of Neuroscience. 17: 1329-37. PMID 12713636 DOI: 10.1046/j.1460-9568.2003.02564.x  0.514
2003 Maggi L, Le Magueresse C, Changeux JP, Cherubini E. Nicotine activates immature "silent" connections in the developing hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 100: 2059-64. PMID 12582205 DOI: 10.1073/pnas.0437947100  0.802
2002 Champtiaux N, Changeux JP. Knock-out and knock-in mice to investigate the role of nicotinic receptors in the central nervous system. Current Drug Targets. Cns and Neurological Disorders. 1: 319-30. PMID 12769606  0.302
2002 Le Novère N, Corringer PJ, Changeux JP. The diversity of subunit composition in nAChRs: evolutionary origins, physiologic and pharmacologic consequences. Journal of Neurobiology. 53: 447-56. PMID 12436412 DOI: 10.1002/neu.10153  0.464
2002 Marchand S, Devillers-Thiéry A, Pons S, Changeux JP, Cartaud J. Rapsyn escorts the nicotinic acetylcholine receptor along the exocytic pathway via association with lipid rafts. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8891-901. PMID 12388596 DOI: 10.1523/Jneurosci.22-20-08891.2002  0.367
2002 Martinez KL, Gohon Y, Corringer PJ, Tribet C, Mérola F, Changeux JP, Popot JL. Allosteric transitions of Torpedo acetylcholine receptor in lipids, detergent and amphipols: molecular interactions vs. physical constraints. Febs Letters. 528: 251-6. PMID 12297315 DOI: 10.1016/S0014-5793(02)03306-9  0.357
2002 Cohen G, Han ZY, Grailhe R, Gallego J, Gaultier C, Changeux JP, Lagercrantz H. beta 2 nicotinic acetylcholine receptor subunit modulates protective responses to stress: A receptor basis for sleep-disordered breathing after nicotine exposure. Proceedings of the National Academy of Sciences of the United States of America. 99: 13272-7. PMID 12228730 DOI: 10.1073/Pnas.192463599  0.349
2002 Ferrari R, Le Novère N, Picciotto MR, Changeux JP, Zoli M. Acute and long-term changes in the mesolimbic dopamine pathway after systemic or local single nicotine injections. The European Journal of Neuroscience. 15: 1810-8. PMID 12081661 DOI: 10.1046/j.1460-9568.2001.02009.x  0.483
2002 Fruchart-Gaillard C, Gilquin B, Antil-Delbeke S, Le Novère N, Tamiya T, Corringer PJ, Changeux JP, Ménez A, Servent D. Experimentally based model of a complex between a snake toxin and the alpha 7 nicotinic receptor. Proceedings of the National Academy of Sciences of the United States of America. 99: 3216-21. PMID 11867717 DOI: 10.1073/Pnas.042699899  0.456
2002 Le Novère N, Grutter T, Changeux JP. Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca2+-binding sites. Proceedings of the National Academy of Sciences of the United States of America. 99: 3210-5. PMID 11867716 DOI: 10.1073/Pnas.042699699  0.735
2002 Champtiaux N, Han ZY, Bessis A, Rossi FM, Zoli M, Marubio L, McIntosh JM, Changeux JP. Distribution and pharmacology of alpha 6-containing nicotinic acetylcholine receptors analyzed with mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 1208-17. PMID 11850448  0.526
2002 Laudenbach V, Medja F, Zoli M, Rossi FM, Evrard P, Changeux JP, Gressens P. Selective activation of central subtypes of the nicotinic acetylcholine receptor has opposite effects on neonatal excitotoxic brain injuries. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 423-5. PMID 11790724 DOI: 10.1096/Fj.01-0532Fje  0.59
2002 Champtiaux N, Han Z, Bessis A, Rossi FM, Zoli M, Marubio L, McIntosh JM, Changeux J. Distribution and Pharmacology of α6-Containing Nicotinic Acetylcholine Receptors Analyzed with Mutant Mice The Journal of Neuroscience. 22: 1208-1217. DOI: 10.1523/Jneurosci.22-04-01208.2002  0.576
2001 Le Novère N, Changeux JP. The Ligand Gated Ion Channel database: an example of a sequence database in neuroscience. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 356: 1121-30. PMID 11545694 DOI: 10.1098/rstb.2001.0903  0.366
2001 Grutter T, Changeux JP. Nicotinic receptors in wonderland. Trends in Biochemical Sciences. 26: 459-63. PMID 11504610 DOI: 10.1016/S0968-0004(01)01921-1  0.74
2001 Schaeffer L, de Kerchove d'Exaerde A, Changeux JP. Targeting transcription to the neuromuscular synapse. Neuron. 31: 15-22. PMID 11498047 DOI: 10.1016/S0896-6273(01)00353-1  0.323
2001 Lukas RJ, Lucero L, Buisson B, Galzi JL, Puchacz E, Fryer JD, Changeux JP, Bertrand D. Neurotoxicity of channel mutations in heterologously expressed alpha7-nicotinic acetylcholine receptors. The European Journal of Neuroscience. 13: 1849-60. PMID 11403678 DOI: 10.1046/J.0953-816X.2001.01560.X  0.656
2001 Changeux JP, Edelstein SJ. Allosteric mechanisms in normal and pathological nicotinic acetylcholine receptors Current Opinion in Neurobiology. 11: 369-377. PMID 11399437 DOI: 10.1016/S0959-4388(00)00221-X  0.665
2001 Changeux JP. Cajal on neurons, molecules, and consciousness. Annals of the New York Academy of Sciences. 929: 147-51. PMID 11349423 DOI: 10.1111/J.1749-6632.2001.Tb05713.X  0.315
2001 Rossi FM, Pizzorusso T, Porciatti V, Marubio LM, Maffei L, Changeux JP. Requirement of the nicotinic acetylcholine receptor beta 2 subunit for the anatomical and functional development of the visual system. Proceedings of the National Academy of Sciences of the United States of America. 98: 6453-8. PMID 11344259 DOI: 10.1073/Pnas.101120998  0.631
2001 Bohler S, Gay S, Bertrand S, Corringer PJ, Edelstein SJ, Changeux JP, Bertrand D. Desensitization of neuronal nicotinic acetylcholine receptors conferred by N-terminal segments of the beta 2 subunit. Biochemistry. 40: 2066-74. PMID 11329274 DOI: 10.1021/Bi0020022  0.643
2001 Zachariou V, Caldarone BJ, Weathers-Lowin A, George TP, Elsworth JD, Roth RH, Changeux JP, Picciotto MR. Nicotine receptor inactivation decreases sensitivity to cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 576-89. PMID 11282258 DOI: 10.1016/S0893-133X(00)00224-4  0.774
2001 Fischer M, Corringer PJ, Schott K, Bacher A, Changeux JP. A method for soluble overexpression of the alpha7 nicotinic acetylcholine receptor extracellular domain. Proceedings of the National Academy of Sciences of the United States of America. 98: 3567-70. PMID 11248118 DOI: 10.1073/pnas.041594798  0.403
2001 Cordero-Erausquin M, Changeux JP. Tonic nicotinic modulation of serotoninergic transmission in the spinal cord. Proceedings of the National Academy of Sciences of the United States of America. 98: 2803-7. PMID 11226321 DOI: 10.1073/pnas.041600698  0.339
2001 Klink R, de Kerchove d'Exaerde A, Zoli M, Changeux JP. Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1452-63. PMID 11222635 DOI: 10.1523/Jneurosci.21-05-01452.2001  0.39
2001 Grady SR, Meinerz NM, Cao J, Reynolds AM, Picciotto MR, Changeux JP, McIntosh JM, Marks MJ, Collins AC. Nicotinic agonists stimulate acetylcholine release from mouse interpeduncular nucleus: a function mediated by a different nAChR than dopamine release from striatum. Journal of Neurochemistry. 76: 258-68. PMID 11145999 DOI: 10.1046/j.1471-4159.2001.00019.x  0.495
2001 Le Novère N, Changeux JP. LGICdb: the ligand-gated ion channel database. Nucleic Acids Research. 29: 294-5. PMID 11125117 DOI: 10.1093/Nar/29.1.294  0.319
2000 Dehaene S, Changeux JP. Reward-dependent learning in neuronal networks for planning and decision making. Progress in Brain Research. 126: 217-29. PMID 11105649 DOI: 10.1016/S0079-6123(00)26016-0  0.589
2000 Marks MJ, Stitzel JA, Grady SR, Picciotto MR, Changeux JP, Collins AC. Nicotinic-agonist stimulated (86)Rb(+) efflux and [(3)H]epibatidine binding of mice differing in beta2 genotype. Neuropharmacology. 39: 2632-45. PMID 11044733 DOI: 10.1016/S0028-3908(00)00115-5  0.597
2000 Tsuneki H, Klink R, Léna C, Korn H, Changeux JP. Calcium mobilization elicited by two types of nicotinic acetylcholine receptors in mouse substantia nigra pars compacta. The European Journal of Neuroscience. 12: 2475-85. PMID 10947823 DOI: 10.1046/J.1460-9568.2000.00138.X  0.378
2000 Antil-Delbeke S, Gaillard C, Tamiya T, Corringer PJ, Changeux JP, Servent D, Ménez A. Molecular determinants by which a long chain toxin from snake venom interacts with the neuronal alpha 7-nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 275: 29594-601. PMID 10852927 DOI: 10.1074/Jbc.M909746199  0.312
2000 Martinez KL, Corringer PJ, Edelstein SJ, Changeux JP, Mérola F. Structural differences in the two agonist binding sites of the Torpedo nicotinic acetylcholine receptor revealed by time-resolved fluorescence spectroscopy. Biochemistry. 39: 6979-90. PMID 10841780 DOI: 10.1021/bi992811p  0.581
2000 Cordero-Erausquin M, Marubio LM, Klink R, Changeux JP. Nicotinic receptor function: new perspectives from knockout mice. Trends in Pharmacological Sciences. 21: 211-7. PMID 10838608 DOI: 10.1016/S0165-6147(00)01489-9  0.42
2000 Corringer PJ, Le Novère N, Changeux JP. Nicotinic receptors at the amino acid level. Annual Review of Pharmacology and Toxicology. 40: 431-58. PMID 10836143 DOI: 10.1146/annurev.pharmtox.40.1.431  0.413
2000 Servent D, Antil-Delbeke S, Gaillard C, Corringer PJ, Changeux JP, Ménez A. Molecular characterization of the specificity of interactions of various neurotoxins on two distinct nicotinic acetylcholine receptors. European Journal of Pharmacology. 393: 197-204. PMID 10771013 DOI: 10.1016/S0014-2999(00)00095-9  0.34
2000 Whiteaker P, Marks MJ, Grady SR, Lu Y, Picciotto MR, Changeux JP, Collins AC. Pharmacological and null mutation approaches reveal nicotinic receptor diversity. European Journal of Pharmacology. 393: 123-35. PMID 10771005 DOI: 10.1016/S0014-2999(00)00052-2  0.624
2000 Marubio LM, Changeux JP. Nicotinic acetylcholine receptor knockout mice as animal models for studying receptor function European Journal of Pharmacology. 393: 113-121. PMID 10771004 DOI: 10.1016/S0014-2999(00)00007-8  0.482
2000 Gisiger T, Dehaene S, Changeux JP. Computational models of association cortex. Current Opinion in Neurobiology. 10: 250-9. PMID 10753797 DOI: 10.1016/S0959-4388(00)00075-1  0.558
2000 Nghiêm HO, Bettendorff L, Changeux JP. Specific phosphorylation of Torpedo 43K rapsyn by endogenous kinase(s) with thiamine triphosphate as the phosphate donor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 14: 543-54. PMID 10698970 DOI: 10.1096/Fasebj.14.3.543  0.357
2000 Paas Y, Devillers-Thiéry A, Teichberg VI, Changeux JP, Eisenstein M. How well can molecular modelling predict the crystal structure: the case of the ligand-binding domain of glutamate receptors. Trends in Pharmacological Sciences. 21: 87-92. PMID 10689361 DOI: 10.1016/S0165-6147(99)01443-1  0.625
2000 Changeux JP, Dehaene S. Hierarchical neuronal modeling of cognitive functions: from synaptic transmission to the Tower of London. International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology. 35: 179-87. PMID 10677646 DOI: 10.1016/S0167-8760(99)00052-5  0.642
2000 Changeux JP. Nicotinic receptors: From molecular biology to psychiatric diseases American Journal of Medical Genetics - Neuropsychiatric Genetics. 96: 453.  0.334
1999 Picciotto MR, Zoli M, Changeux JP. Use of knock-out mice to determine the molecular basis for the actions of nicotine. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 1: S121-5; discussion S. PMID 11768168 DOI: 10.1080/14622299050011931  0.622
1999 Epping-Jordan MP, Picciotto MR, Changeux JP, Pich EM. Assessment of nicotinic acetylcholine receptor subunit contributions to nicotine self-administration in mutant mice. Psychopharmacology. 147: 25-6. PMID 10591862 DOI: 10.1007/s002130051135  0.599
1999 le Novère N, Zoli M, Léna C, Ferrari R, Picciotto MR, Merlo-Pich E, Changeux JP. Involvement of alpha6 nicotinic receptor subunit in nicotine-elicited locomotion, demonstrated by in vivo antisense oligonucleotide infusion. Neuroreport. 10: 2497-501. PMID 10574359  0.568
1999 Léna C, de Kerchove D'Exaerde A, Cordero-Erausquin M, Le Novère N, del Mar Arroyo-Jimenez M, Changeux JP. Diversity and distribution of nicotinic acetylcholine receptors in the locus ceruleus neurons. Proceedings of the National Academy of Sciences of the United States of America. 96: 12126-31. PMID 10518587 DOI: 10.1073/Pnas.96.21.12126  0.428
1999 Corringer PJ, Bertrand S, Galzi JL, Devillers-Thiéry A, Changeux JP, Bertrand D. Molecular basis of the charge selectivity of nicotinic acetylcholine receptor and related ligand-gated ion channels. Novartis Foundation Symposium. 225: 215-24; discussion 2. PMID 10472058 DOI: 10.1002/9780470515716.Ch14  0.698
1999 Léna C, Changeux JP. The role of beta 2-subunit-containing nicotinic acetylcholine receptors in the brain explored with a mutant mouse. Annals of the New York Academy of Sciences. 868: 611-6. PMID 10414341 DOI: 10.1111/J.1749-6632.1999.Tb11333.X  0.459
1999 Lukas RJ, Changeux JP, Le Novère N, Albuquerque EX, Balfour DJ, Berg DK, Bertrand D, Chiappinelli VA, Clarke PB, Collins AC, Dani JA, Grady SR, Kellar KJ, Lindstrom JM, Marks MJ, et al. International Union of Pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits. Pharmacological Reviews. 51: 397-401. PMID 10353988  0.763
1999 Marubio LM, del Mar Arroyo-Jimenez M, Cordero-Erausquin M, Léna C, Le Novère N, de Kerchove d'Exaerde A, Huchet M, Damaj MI, Changeux JP. Reduced antinociception in mice lacking neuronal nicotinic receptor subunits. Nature. 398: 805-10. PMID 10235262 DOI: 10.1038/19756  0.455
1999 Le Novère N, Corringer PJ, Changeux JP. Improved secondary structure predictions for a nicotinic receptor subunit: incorporation of solvent accessibility and experimental data into a two-dimensional representation. Biophysical Journal. 76: 2329-45. PMID 10233052 DOI: 10.1016/S0006-3495(99)77390-X  0.383
1999 Corringer PJ, Bertrand S, Galzi JL, Devillers-Thiéry A, Changeux JP, Bertrand D. Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor. Neuron. 22: 831-43. PMID 10230802 DOI: 10.1016/S0896-6273(00)80741-2  0.666
1999 Marks MJ, Whiteaker P, Calcaterra J, Stitzel JA, Bullock AE, Grady SR, Picciotto MR, Changeux JP, Collins AC. Two pharmacologically distinct components of nicotinic receptor-mediated rubidium efflux in mouse brain require the beta2 subunit. The Journal of Pharmacology and Experimental Therapeutics. 289: 1090-103. PMID 10215692  0.537
1999 Salmon AM, Damaj I, Sekine S, Picciotto MR, Marubio L, Changeux JP. Modulation of morphine analgesia in alphaCGRP mutant mice. Neuroreport. 10: 849-54. PMID 10208559 DOI: 10.1097/00001756-199903170-00033  0.48
1999 Zoli M, Picciotto MR, Ferrari R, Cocchi D, Changeux JP. Increased neurodegeneration during ageing in mice lacking high-affinity nicotine receptors. The Embo Journal. 18: 1235-44. PMID 10064590 DOI: 10.1093/emboj/18.5.1235  0.565
1999 Le Novère N, Changeux JP. The Ligand Gated Ion Channel Database. Nucleic Acids Research. 27: 340-2. PMID 9847222 DOI: 10.1093/nar/27.1.340  0.358
1999 Arroyo-Jiménez MdM, Bourgeois J, Marubio LM, Sourd AL, Ottersen OP, Rinvik E, Fairén A, Changeux J. Ultrastructural Localization of the α4-Subunit of the Neuronal Acetylcholine Nicotinic Receptor in the Rat Substantia Nigra The Journal of Neuroscience. 19: 6475-6487. DOI: 10.1523/Jneurosci.19-15-06475.1999  0.378
1998 Changeux JP, Edelstein SJ. Allosteric receptors after 30 years. Neuron. 21: 959-80. PMID 9856454 DOI: 10.1016/S0896-6273(00)80616-9  0.657
1998 Dehaene S, Kerszberg M, Changeux JP. A neuronal model of a global workspace in effortful cognitive tasks. Proceedings of the National Academy of Sciences of the United States of America. 95: 14529-34. PMID 9826734 DOI: 10.1073/pnas.95.24.14529  0.578
1998 Servent D, Thanh HL, Antil S, Bertrand D, Corringer PJ, Changeux JP, Ménez A. Functional determinants by which snake and cone snail toxins block the alpha 7 neuronal nicotinic acetylcholine receptors. Journal of Physiology, Paris. 92: 107-11. PMID 9782452 DOI: 10.1016/S0928-4257(98)80146-0  0.363
1998 Léna C, Changeux JP. Allosteric nicotinic receptors, human pathologies. Journal of Physiology, Paris. 92: 63-74. PMID 9782446 DOI: 10.1016/S0928-4257(98)80140-X  0.462
1998 Changeux JP, Dehaene S. Hierarchical neuronal modeling of cognitive functions: from synaptic transmission to the Tower of London. Comptes Rendus De L'Acadã©Mie Des Sciences. Sã©Rie Iii, Sciences De La Vie. 321: 241-7. PMID 9759348 DOI: 10.1016/S0764-4469(97)89829-0  0.642
1998 Watanabe H, Zoli M, Changeux JP. Promoter analysis of the neuronal nicotinic acetylcholine receptor alpha4 gene: methylation and expression of the transgene. The European Journal of Neuroscience. 10: 2244-53. PMID 9749753 DOI: 10.1046/J.1460-9568.1998.00235.X  0.356
1998 Changeux JP, Bertrand D, Corringer PJ, Dehaene S, Edelstein S, Léna C, Le Novère N, Marubio L, Picciotto M, Zoli M. Brain nicotinic receptors: structure and regulation, role in learning and reinforcement. Brain Research. Brain Research Reviews. 26: 198-216. PMID 9651527 DOI: 10.1016/S0165-0173(97)00040-4  0.775
1998 Edelstein SJ, Changeux JP. Allosteric transitions of the acetylcholine receptor. Advances in Protein Chemistry. 51: 121-84. PMID 9615170 DOI: 10.1016/S0065-3233(08)60652-X  0.622
1998 Zoli M, Léna C, Picciotto MR, Changeux JP. Identification of four classes of brain nicotinic receptors using beta2 mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 4461-72. PMID 9614223  0.578
1998 Schaeffer L, Duclert N, Huchet-Dymanus M, Changeux JP. Implication of a multisubunit Ets-related transcription factor in synaptic expression of the nicotinic acetylcholine receptor. The Embo Journal. 17: 3078-90. PMID 9606190 DOI: 10.1093/emboj/17.11.3078  0.395
1998 Bessereau JL, Laudenbach V, Le Poupon C, Changeux JP. Nonmyogenic factors bind nicotinic acetylcholine receptor promoter elements required for response to denervation. The Journal of Biological Chemistry. 273: 12786-93. PMID 9582305 DOI: 10.1074/Jbc.273.21.12786  0.341
1998 Krause RM, Buisson B, Bertrand S, Corringer PJ, Galzi JL, Changeux JP, Bertrand D. Ivermectin: a positive allosteric effector of the alpha7 neuronal nicotinic acetylcholine receptor. Molecular Pharmacology. 53: 283-94. PMID 9463487 DOI: 10.1124/Mol.53.2.283  0.715
1998 Picciotto MR, Zoli M, Rimondini R, Léna C, Marubio LM, Pich EM, Fuxe K, Changeux JP. Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine. Nature. 391: 173-7. PMID 9428762 DOI: 10.1038/34413  0.616
1998 Corringer PJ, Bertrand S, Bohler S, Edelstein SJ, Changeux JP, Bertrand D. Critical elements determining diversity in agonist binding and desensitization of neuronal nicotinic acetylcholine receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 648-57. PMID 9425007 DOI: 10.1523/Jneurosci.18-02-00648.1998  0.675
1998 Zoli M, Léna C, Picciotto MR, Changeux J. Identification of Four Classes of Brain Nicotinic Receptors Using β2 Mutant Mice The Journal of Neuroscience. 18: 4461-4472. DOI: 10.1523/Jneurosci.18-12-04461.1998  0.778
1998 Laudenbach V, Bessereau JL, Mantz J, Desmonts JM, Changeux JP. IDENTIFICATION OF CRITICAL DNA SEQUENCES INVOLVED IN THE OVEREXPRESSION OF THE NICOTINIC ACETYLCHOLINE RECEPTOR (nAChR) [Greek small leter alpha] SUBUNIT IN THE DENERVATED MUSCLE Anesthesiology. 89: 980A. DOI: 10.1097/00000542-199809170-00009  0.302
1997 Edelstein SJ, Schaad O, Changeux JP. Myasthenic nicotinic receptor mutant interpreted in terms of the allosteric model. Comptes Rendus De L'Acadã©Mie Des Sciences. Sã©Rie Iii, Sciences De La Vie. 320: 953-61. PMID 9587473 DOI: 10.1016/S0764-4469(97)82468-7  0.595
1997 Bertrand S, Devillers-Thiéry A, Palma E, Buisson B, Edelstein SJ, Corringer PJ, Changeux JP, Bertrand D. Paradoxical allosteric effects of competitive inhibitors on neuronal alpha7 nicotinic receptor mutants. Neuroreport. 8: 3591-6. PMID 9427332 DOI: 10.1097/00001756-199711100-00034  0.592
1997 Picciotto MR, Zoli M, Zachariou V, Changeux JP. Contribution of nicotinic acetylcholine receptors containing the beta 2-subunit to the behavioural effects of nicotine. Biochemical Society Transactions. 25: 824-9. PMID 9388554 DOI: 10.1042/Bst0250824  0.73
1997 Léna C, Changeux JP. Pathological mutations of nicotinic receptors and nicotine-based therapies for brain disorders. Current Opinion in Neurobiology. 7: 674-82. PMID 9384554 DOI: 10.1016/S0959-4388(97)80088-8  0.406
1997 Edelstein SJ, Schaad O, Changeux JP. Single binding versus single channel recordings: a new approach to study ionotropic receptors. Biochemistry. 36: 13755-60. PMID 9374851 DOI: 10.1021/Bi9718301  0.612
1997 Dehaene S, Changeux JP. A hierarchical neuronal network for planning behavior. Proceedings of the National Academy of Sciences of the United States of America. 94: 13293-8. PMID 9371839 DOI: 10.1073/pnas.94.24.13293  0.568
1997 Bessis A, Champtiaux N, Chatelin L, Changeux JP. The neuron-restrictive silencer element: a dual enhancer/silencer crucial for patterned expression of a nicotinic receptor gene in the brain. Proceedings of the National Academy of Sciences of the United States of America. 94: 5906-11. PMID 9159173 DOI: 10.1073/Pnas.94.11.5906  0.361
1997 Altiok N, Altiok S, Changeux JP. Heregulin-stimulated acetylcholine receptor gene expression in muscle: requirement for MAP kinase and evidence for a parallel inhibitory pathway independent of electrical activity. The Embo Journal. 16: 717-25. PMID 9049301 DOI: 10.1093/emboj/16.4.717  0.315
1997 Léna C, Changeux JP. Role of Ca2+ ions in nicotinic facilitation of GABA release in mouse thalamus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 576-85. PMID 8987780 DOI: 10.1523/Jneurosci.17-02-00576.1997  0.4
1996 Edelstein SJ, Changeux JP. Allosteric proteins after thirty years: the binding and state functions of the neuronal alpha 7 nicotinic acetylcholine receptors. Experientia. 52: 1083-90. PMID 8988250 DOI: 10.1007/Bf01952106  0.644
1996 Edelstein SJ, Schaad O, Henry E, Bertrand D, Changeux JP. A kinetic mechanism for nicotinic acetylcholine receptors based on multiple allosteric transitions. Biological Cybernetics. 75: 361-79. PMID 8983160 DOI: 10.1007/S004220050302  0.632
1996 Galzi JL, Bertrand S, Corringer PJ, Changeux JP, Bertrand D. Identification of calcium binding sites that regulate potentiation of a neuronal nicotinic acetylcholine receptor. The Embo Journal. 15: 5824-32. PMID 8918460  0.637
1996 Milton NG, Bessis A, Changeux JP, Latchman DS. Differential regulation of neuronal nicotinic acetylcholine receptor subunit gene promoters by Brn-3 POU family transcription factors. The Biochemical Journal. 317: 419-23. PMID 8713067 DOI: 10.1042/Bj3170419  0.399
1996 Galzi JL, Edelstein SJ, Changeux J. The multiple phenotypes of allosteric receptor mutants. Proceedings of the National Academy of Sciences of the United States of America. 93: 1853-8. PMID 8700848 DOI: 10.1073/Pnas.93.5.1853  0.768
1996 Duclert A, Savatier N, Schaeffer L, Changeux JP. Identification of an element crucial for the sub-synaptic expression of the acetylcholine receptor epsilon-subunit gene. The Journal of Biological Chemistry. 271: 17433-8. PMID 8663316 DOI: 10.1074/Jbc.271.29.17433  0.351
1996 Paas Y, Devillers-Thiéry A, Changeux JP, Medevielle F, Teichberg VI. Identification of an extracellular motif involved in the binding of guanine nucleotides by a glutamate receptor. The Embo Journal. 15: 1548-56. PMID 8612578 DOI: 10.1002/J.1460-2075.1996.Tb00499.X  0.581
1996 Changeux J, Bessis A, Picciotto M, Zoli M. 35 Nicotinic receptors (nAChR) in the brain : Gene expression and contribution to learning and aging processes Neurobiology of Aging. 17: S9-S10. DOI: 10.1016/S0197-4580(96)80037-6  0.572
1996 Vidal C, Changeux JP. Neuronal nicotinic acetylcholine receptors in the brain News in Physiological Sciences. 11: 202-214.  0.309
1995 Bessis A, Salmon AM, Zoli M, Le Novère N, Picciotto M, Changeux JP. Promoter elements conferring neuron-specific expression of the beta 2-subunit of the neuronal nicotinic acetylcholine receptor studied in vitro and in transgenic mice. Neuroscience. 69: 807-19. PMID 8596650 DOI: 10.1016/0306-4522(95)00303-Z  0.546
1995 Dehaene S, Changeux JP. Neuronal models of prefrontal cortical functions. Annals of the New York Academy of Sciences. 769: 305-19. PMID 8595034 DOI: 10.1111/j.1749-6632.1995.tb38147.x  0.574
1995 Picciotto MR, Zoli M, Léna C, Bessis A, Lallemand Y, Le Novère N, Vincent P, Pich EM, Brûlet P, Changeux JP. Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain. Nature. 374: 65-7. PMID 7870173 DOI: 10.1038/374065A0  0.619
1995 Milton NG, Bessis A, Changeux JP, Latchman DS. The neuronal nicotinic acetylcholine receptor alpha 2 subunit gene promoter is activated by the Brn-3b POU family transcription factor and not by Brn-3a or Brn-3c. The Journal of Biological Chemistry. 270: 15143-7. PMID 7797498 DOI: 10.1074/Jbc.270.25.15143  0.362
1995 Corringer PJ, Galzi JL, Eiselé JL, Bertrand S, Changeux JP, Bertrand D. Identification of a new component of the agonist binding site of the nicotinic alpha 7 homooligomeric receptor. The Journal of Biological Chemistry. 270: 11749-52. PMID 7744821 DOI: 10.1074/Jbc.270.20.11749  0.692
1995 Duclert A, Changeux JP. Acetylcholine receptor gene expression at the developing neuromuscular junction. Physiological Reviews. 75: 339-68. PMID 7724666 DOI: 10.1152/Physrev.1995.75.2.339  0.359
1995 Le Novère N, Changeux JP. Molecular evolution of the nicotinic acetylcholine receptor: an example of multigene family in excitable cells. Journal of Molecular Evolution. 40: 155-72. PMID 7699721 DOI: 10.1007/Bf00167110  0.424
1995 Li XM, Zoli M, Finnman UB, Le Novère N, Changeux JP, Fuxe K. A single (-)-nicotine injection causes change with a time delay in the affinity of striatal D2 receptors for antagonist, but not for agonist, nor in the D2 receptor mRNA levels in the rat substantia nigra. Brain Research. 679: 157-67. PMID 7648259 DOI: 10.1016/0006-8993(95)00228-I  0.41
1995 Galzi JL, Changeux JP. Neuronal nicotinic receptors: molecular organization and regulations. Neuropharmacology. 34: 563-82. PMID 7566492 DOI: 10.1016/0028-3908(95)00034-4  0.659
1995 Froehner SC, Huganir RL, Cohen JB, Changeux J. John Paul Merlie (1945–1995) Neuron. 15: 21. DOI: 10.1016/0896-6273(95)90060-8  0.342
1995 Bertrand D, Changeux JP. Nicotinic receptor: An allosteric protein specialized for intercellular communication Seminars in the Neurosciences. 7: 75-90. DOI: 10.1006/Smns.1995.0010  0.458
1994 Changeux JP, Edelstein SJ. On allosteric mechanisms and acetylcholine receptors. Trends in Biochemical Sciences. 19: 399-400. PMID 7817393 DOI: 10.1016/0968-0004(94)90084-1  0.646
1994 Galzi JL, Changeux JP. Neurotransmitter-gated ion channels as unconventional allosteric proteins Current Opinion in Structural Biology. 4: 554-565. DOI: 10.1016/S0959-440X(94)90218-6  0.636
1993 Dehaene S, Changeux JP. Development of elementary numerical abilities: a neuronal model. Journal of Cognitive Neuroscience. 5: 390-407. PMID 23964915 DOI: 10.1162/jocn.1993.5.4.390  0.574
1993 Aslanian D, Grof P, Galzi JL, Changeux JP. A Raman spectroscopic study of acetylcholine receptor-rich membranes from Torpedo marmorata. Interaction of the receptor with carbamylcholine and (+)-tubocurarine. Biochimica Et Biophysica Acta. 1148: 291-302. PMID 8504123 DOI: 10.1016/0005-2736(93)90142-M  0.614
1993 Bessis A, Savatier N, Devillers-Thiéry A, Bejanin S, Changeux JP. Negative regulatory elements upstream of a novel exon of the neuronal nicotinic acetylcholine receptor alpha 2 subunit gene. Nucleic Acids Research. 21: 2185-92. PMID 8502560 DOI: 10.1093/Nar/21.9.2185  0.395
1993 Léna C, Changeux JP, Mulle C. Evidence for "preterminal" nicotinic receptors on GABAergic axons in the rat interpeduncular nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 2680-8. PMID 8501532 DOI: 10.1523/Jneurosci.13-06-02680.1993  0.424
1993 Piette J, Huchet M, Houzelstein D, Changeux JP. Compartmentalized expression of the alpha- and gamma-subunits of the acetylcholine receptor in recently fused myofibers. Developmental Biology. 157: 205-13. PMID 8482411 DOI: 10.1006/dbio.1993.1124  0.365
1993 Daubas P, Salmon AM, Zoli M, Geoffroy B, Devillers-Thiéry A, Bessis A, Médevielle F, Changeux JP. Chicken neuronal acetylcholine receptor alpha 2-subunit gene exhibits neuron-specific expression in the brain and spinal cord of transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 90: 2237-41. PMID 8460128 DOI: 10.1073/Pnas.90.6.2237  0.389
1993 Cartaud J, Changeux JP. Post-transcriptional compartmentalization of acetylcholine receptor biosynthesis in the subneural domain of muscle and electrocyte junctions. The European Journal of Neuroscience. 5: 191-202. PMID 8261100 DOI: 10.1111/J.1460-9568.1993.Tb00485.X  0.33
1993 Eiselé JL, Bertrand S, Galzi JL, Devillers-Thiéry A, Changeux JP, Bertrand D. Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities. Nature. 366: 479-83. PMID 8247158 DOI: 10.1038/366479A0  0.68
1993 Changeux JP. Allosteric proteins: from regulatory enzymes to receptors--personal recollections. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 15: 625-34. PMID 8240316 DOI: 10.1002/bies.950150909  0.34
1993 Vidal C, Changeux JP. Nicotinic and muscarinic modulations of excitatory synaptic transmission in the rat prefrontal cortex in vitro. Neuroscience. 56: 23-32. PMID 7901807 DOI: 10.1016/0306-4522(93)90558-W  0.304
1993 Bertrand D, Galzi JL, Devillers-Thiéry A, Bertrand S, Changeux JP. Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal alpha 7 nicotinic receptor. Proceedings of the National Academy of Sciences of the United States of America. 90: 6971-5. PMID 7688468 DOI: 10.1073/Pnas.90.15.6971  0.635
1993 Léna C, Changeux JP. Allosteric modulations of the nicotinic acetylcholine receptor. Trends in Neurosciences. 16: 181-6. PMID 7685943 DOI: 10.1016/0166-2236(93)90150-K  0.424
1993 Devillers-Thiéry A, Galzi JL, Eiselé JL, Bertrand S, Bertrand D, Changeux JP. Functional architecture of the nicotinic acetylcholine receptor: a prototype of ligand-gated ion channels. The Journal of Membrane Biology. 136: 97-112. PMID 7508983 DOI: 10.1007/BF02505755  0.651
1993 Bertrand D, Galzi JL, Devillers-Thiéry A, Bertrand S, Changeux JP. Stratification of the channel domain in neurotransmitter receptors. Current Opinion in Cell Biology. 5: 688-93. PMID 7504932 DOI: 10.1016/0955-0674(93)90141-C  0.625
1992 Bertrand D, Devillers-Thiéry A, Revah F, Galzi JL, Hussy N, Mulle C, Bertrand S, Ballivet M, Changeux JP. Unconventional pharmacology of a neuronal nicotinic receptor mutated in the channel domain. Proceedings of the National Academy of Sciences of the United States of America. 89: 1261-5. PMID 1741378 DOI: 10.1073/Pnas.89.4.1261  0.679
1992 Chatrenet B, Kotzba-Hibert F, Mulle C, Changeux JP, Goeldner MP, Hirth C. Photoactivatable agonist of the nicotinic acetylcholine receptor: potential probe to characterize the structural transitions of the acetylcholine binding site in different states of the receptor. Molecular Pharmacology. 41: 1100-6. PMID 1614412  0.598
1992 Mulle C, Léna C, Changeux JP. Potentiation of nicotinic receptor response by external calcium in rat central neurons. Neuron. 8: 937-45. PMID 1586487 DOI: 10.1016/0896-6273(92)90208-U  0.361
1992 Changeux JP. Functional organisation of the nicotinic acetylcholine receptor. Comptes Rendus De L'Acadã©Mie Des Sciences. Sã©Rie Iii, Sciences De La Vie. 314: 89-94. PMID 1422915  0.329
1992 Changeux JP, Devillers-Thiéry A, Galzi JL, Revah F. The acetylcholine receptor: a model of an allosteric membrane protein mediating intercellular communication. Ciba Foundation Symposium. 164: 66-89; discussion 87. PMID 1395936 DOI: 10.1016/0165-6147(79)90070-1  0.693
1992 Changeux JP, Devillers-Thiéry A, Galzi JL, Bertrand D. New mutants to explore nicotinic receptor functions. Trends in Pharmacological Sciences. 13: 299-301. PMID 1384213 DOI: 10.1016/0165-6147(92)90094-M  0.683
1992 Galzi JL, Devillers-Thiéry A, Hussy N, Bertrand S, Changeux JP, Bertrand D. Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic. Nature. 359: 500-5. PMID 1383829 DOI: 10.1038/359500A0  0.685
1992 Mulle C, Choquet D, Korn H, Changeux JP. Calcium influx through nicotinic receptor in rat central neurons: its relevance to cellular regulation. Neuron. 8: 135-43. PMID 1309647 DOI: 10.1016/0896-6273(92)90115-T  0.301
1992 Changeux JP, Galzi JL, Devillers-Thiéry A, Bertrand D. The functional architecture of the acetylcholine nicotinic receptor explored by affinity labelling and site-directed mutagenesis. Quarterly Reviews of Biophysics. 25: 395-432. PMID 1293635 DOI: 10.1017/S0033583500004352  0.657
1992 Devillers-Thiéry A, Galzi JL, Bertrand S, Changeux JP, Bertrand D. Stratified organization of the nicotinic acetylcholine receptor channel. Neuroreport. 3: 1001-4. PMID 1282832 DOI: 10.1097/00001756-199211000-00014  0.642
1992 Kerszberg M, Dehaene S, Changeux JP. Stabilization of complex input-output functions in neural clusters formed by synapse selection Neural Networks. 5: 403-413. DOI: 10.1016/0893-6080(92)90003-2  0.595
1991 Galzi JL, Revah F, Bessis A, Changeux JP. Functional architecture of the nicotinic acetylcholine receptor: from electric organ to brain. Annual Review of Pharmacology and Toxicology. 31: 37-72. PMID 2064379 DOI: 10.1146/annurev.pa.31.040191.000345  0.643
1991 Galzi JL, Revah F, Bouet F, Ménez A, Goeldner M, Hirth C, Changeux JP. Allosteric transitions of the acetylcholine receptor probed at the amino acid level with a photolabile cholinergic ligand. Proceedings of the National Academy of Sciences of the United States of America. 88: 5051-5. PMID 2052586 DOI: 10.1073/Pnas.88.11.5051  0.774
1991 Dehaene S, Changeux JP. The Wisconsin Card Sorting Test: theoretical analysis and modeling in a neuronal network. Cerebral Cortex (New York, N.Y. : 1991). 1: 62-79. PMID 1822726 DOI: 10.1093/cercor/1.1.62  0.578
1991 Duclert A, Piette J, Changeux J. Influence of innervation of myogenic factors and acetylcholine receptor alpha-subunit mRNAs. Neuroreport. 2: 25-28. PMID 1768845 DOI: 10.1097/00001756-199101000-00006  0.324
1991 Laufer R, Klarsfeld A, Changeux JP. Phorbol esters inhibit the activity of the chicken acetylcholine receptor alpha-subunit gene promoter. Role of myogenic regulators. European Journal of Biochemistry / Febs. 202: 813-8. PMID 1765095 DOI: 10.1111/j.1432-1033.1991.tb16437.x  0.698
1991 Galzi JL, Bertrand D, Devillers-Thiéry A, Revah F, Bertrand S, Changeux JP. Functional significance of aromatic amino acids from three peptide loops of the alpha 7 neuronal nicotinic receptor site investigated by site-directed mutagenesis. Febs Letters. 294: 198-202. PMID 1756861 DOI: 10.1016/0014-5793(91)80668-S  0.726
1991 Revah F, Bertrand D, Galzi JL, Devillers-Thiéry A, Mulle C, Hussy N, Bertrand S, Ballivet M, Changeux JP. Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor. Nature. 353: 846-9. PMID 1719423 DOI: 10.1038/353846A0  0.659
1991 Mulle C, Vidal C, Benoit P, Changeux J. Existence of different subtypes of nicotinic acetylcholine receptors in the rat habenulo-interpeduncular system The Journal of Neuroscience. 11: 2588-2597. DOI: 10.1523/Jneurosci.11-08-02588.1991  0.457
1991 Changeux JP. Functional organization of the nicotinic acetylcholine receptor European Neuropsychopharmacology. 1: 305-307. DOI: 10.1016/0924-977X(91)90538-6  0.309
1990 Changeux JP, Fontaine B, Klarsfeld A, Laufer R, Cartaud J. Molecular biology of acetylcholine receptor long-term evolution during motor end-plate morphogenesis. Progress in Brain Research. 79: 15-25. PMID 2685894 DOI: 10.1016/S0079-6123(08)62462-0  0.743
1990 Galzi JL, Revah F, Black D, Goeldner M, Hirth C, Changeux JP. Identification of a novel amino acid alpha-tyrosine 93 within the cholinergic ligands-binding sites of the acetylcholine receptor by photoaffinity labeling. Additional evidence for a three-loop model of the cholinergic ligands-binding sites. The Journal of Biological Chemistry. 265: 10430-7. PMID 2355008  0.74
1990 Bessis A, Simon-Chazottes D, Devillers-Thiéry A, Guénet JL, Changeux JP. Chromosomal localization of the mouse genes coding for alpha 2, alpha 3, alpha 4 and beta 2 subunits of neuronal nicotinic acetylcholine receptor. Febs Letters. 264: 48-52. PMID 2338144 DOI: 10.1016/0014-5793(90)80761-7  0.396
1990 Jasmin BJ, Changeux JP, Cartaud J. Compartmentalization of cold-stable and acetylated microtubules in the subsynaptic domain of chick skeletal muscle fibre Nature. 344: 673-675. PMID 2325774 DOI: 10.1038/344673A0  0.307
1990 Duclert A, Piette J, Changeux J. Induction of acetylcholine receptor alpha-subunit gene expression in chicken myotubes by blocking electrical activity requires ongoing protein synthesis. Proceedings of the National Academy of Sciences of the United States of America. 87: 1391-1395. PMID 2304905 DOI: 10.1073/Pnas.87.4.1391  0.347
1990 Mulle C, Changeux JP. A novel type of nicotinic receptor in the rat central nervous system characterized by patch-clamp techniques Journal of Neuroscience. 10: 169-175. PMID 2299390 DOI: 10.1523/Jneurosci.10-01-00169.1990  0.44
1990 Changeux JP, Benoît P, Bessis A, Cartaud J, Devillers-Thiéry A, Fontaine B, Galzi JL, Klarsfeld A, Laufer R, Mulle C. Regulation of acetylcholine receptor gene expression by neural factors and electrical activity during motor endplate formation. Biochemical Society Symposium. 56: 9-12. PMID 2256962  0.596
1990 Changeux JP. The TiPS lecture the nicotinic acetylcholine receptor: an allosteric protein prototype of ligand-gated ion channels Trends in Pharmacological Sciences. 11: 485-492. PMID 2080554 DOI: 10.1016/0165-6147(90)90049-E  0.385
1990 Changeux JP, Benoit P, Bessis A, Cartaud J, Devillers-Thiery A, Fontaine B, Galzi JL, Klarsfeld A, Laufer R, Mulle C. The acetylcholine receptor: functional architecture and regulation. Advances in Second Messenger and Phosphoprotein Research. 24: 15-9. PMID 1698404  0.634
1990 Revah F, Galzi JL, Giraudat J, Haumont PY, Lederer F, Changeux JP. The noncompetitive blocker [3H]chlorpromazine labels three amino acids of the acetylcholine receptor gamma subunit: implications for the alpha-helical organization of regions MII and for the structure of the ion channel. Proceedings of the National Academy of Sciences of the United States of America. 87: 4675-9. PMID 1693775  0.64
1989 Dehaene S, Changeux JP. A simple model of prefrontal cortex function in delayed-response tasks. Journal of Cognitive Neuroscience. 1: 244-61. PMID 23968508 DOI: 10.1162/jocn.1989.1.3.244  0.566
1989 Vidal C, Changeux JP. Pharmacological profile of nicotinic acetylcholine receptors in the rat prefrontal cortex: An electrophysiological study in a slice preparation Neuroscience. 29: 261-270. PMID 2725858 DOI: 10.1016/0306-4522(89)90056-0  0.349
1989 Changeux JP, Dehaene S. Neuronal models of cognitive functions. Cognition. 33: 63-109. PMID 2691185 DOI: 10.1016/0010-0277(89)90006-1  0.597
1989 Laufer R, Changeux JP. Activity-dependent regulation of gene expression in muscle and neuronal cells Molecular Neurobiology. 3: 1-53. PMID 2679765 DOI: 10.1007/BF02935587  0.374
1989 Giraudat J, Galzi JL, Revah F, Changeux JP, Haumont PY, Lederer F. The noncompetitive blocker [3H]chlorpromazine labels segment M2 but not segment M 1 of the nicotinic acetylcholine receptor α-subunit Febs Letters. 253: 190-198. PMID 2474458 DOI: 10.1016/0014-5793(89)80957-3  0.671
1989 Changeux JP. The acetylcholine receptor: its molecular biology and biotechnological prospects Bioessays. 10: 48-54. PMID 2470366 DOI: 10.1002/Bies.950100204  0.384
1989 Hill J, Nghiêm H, Changeux J. The nicotinic receptor-associated 43K protein is a phosphoprotein Cell Differentiation and Development. 27: 195. DOI: 10.1016/0922-3371(89)90590-X  0.384
1988 Dehaene S, Changeux JP. Selectionist mechanisms: A framework for interactionism Behavioral and Brain Sciences. 11: 633. DOI: 10.1017/S0140525X00053747  0.542
1987 Henderson CE, Hauser SL, Huchet M, Dessi F, Hentati F, Taguchi T, Changeux JP, Fardeau M. Extracts of muscle biopsies from patients with spinal muscular atrophies inhibit neurite outgrowth from spinal neurons. Neurology. 37: 1361-4. PMID 3614658  0.406
1987 Fontaine B, Klarsfeld A, Hökfelt T, Changeux JP. Calcitonin gene-related peptide, a peptide present in spinal cord motoneurons, increases the number of acetylcholine receptors in primary cultures of chick embryo myotubes. Neuroscience Letters. 71: 59-65. PMID 3491345 DOI: 10.1016/0304-3940(86)90257-0  0.663
1987 Dehaene S, Changeux JP, Nadal JP. Neural networks that learn temporal sequences by selection. Proceedings of the National Academy of Sciences of the United States of America. 84: 2727-31. PMID 3472233 DOI: 10.1073/Pnas.84.9.2727  0.585
1987 Taguchi T, Huchet M, Roa M, Changeux JP, Henderson CE. A subpopulation of embryonic telencephalic neurons survive and develop in vitro in response to factors derived from the periphery. Brain Research. 465: 125-32. PMID 3440197 DOI: 10.1016/0165-3806(87)90234-3  0.503
1987 Changeux JP, Revah F. The acetylcholine receptor molecule: allosteric sites and the ion channel Trends in Neurosciences. 10: 245-250. DOI: 10.1016/0166-2236(87)90167-6  0.421
1987 Changeux J, Giraudat J, Dennis M. The nicotinic acetylcholine receptor: Molecular architecture of a ligand-regulated ion channel Trends in Pharmacological Sciences. 8: 459-465. DOI: 10.1016/0165-6147(87)90039-3  0.397
1986 Henderson CE, Benoit P, Huchet M, Guenet JL, Changeux JP. Increase of neurite-promoting activity for spinal neurons in muscles of 'paralysé' mice and tenotomised rats. Brain Research. 390: 65-70. PMID 3948032 DOI: 10.1016/0165-3806(86)90152-5  0.487
1986 Hauser SL, Cazenave PA, Lyon-Caen O, Taguchi T, Huchet M, Nuret H, Changeux JP, Henderson CE. Immunoblot analysis of circulating antibodies against muscle proteins in amyotrophic lateral sclerosis and other neurologic diseases. Neurology. 36: 1614-8. PMID 3785679 DOI: 10.1212/Wnl.36.12.1614  0.458
1986 Toulouse G, Dehaene S, Changeux JP. Spin glass model of learning by selection. Proceedings of the National Academy of Sciences of the United States of America. 83: 1695-8. PMID 3456609 DOI: 10.1073/Pnas.83.6.1695  0.569
1986 Giraudat J, Dennis M, Heidmann T, Chang J, Changeux J. Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: serine-262 of the delta subunit is labeled by [3H]chlorpromazine. Proceedings of the National Academy of Sciences of the United States of America. 83: 2719-2723. PMID 3085104 DOI: 10.1073/Pnas.83.8.2719  0.385
1986 Heidmann O, Buonanno A, Geoffroy B, Robert B, Guénet JL, Merlie JP, Changeux JP. Chromosomal localization of muscle nicotinic acetylcholine receptor genes in the mouse. Science (New York, N.Y.). 234: 866-8. PMID 3022377 DOI: 10.1126/Science.3022377  0.694
1986 Dennis M, Giraudat J, Kotzyba-Hibert F, Goeldner M, Hirth C, Chang JY, Changeux JP. A photoaffinity ligand of the acetylcholine-binding site predominantly labels the region 179-207 of the α-subunit on native acetylcholine receptor from Torpedo marmorata Febs Letters. 207: 243-249. DOI: 10.1016/0014-5793(86)81497-1  0.772
1985 Chemouilli P, Heidmann T, Changeux J, Bachy A, Morre M. Allosteric effects of diprobutine on acetylcholine receptors European Journal of Pharmacology. 117: 205-214. PMID 3000803 DOI: 10.1016/0014-2999(85)90605-3  0.405
1985 Klarsfeld A, Changeux JP. Activity regulates the levels of acetylcholine receptor α-subunit mRNA in cultured chicken myotubes Proceedings of the National Academy of Sciences of the United States of America. 82: 4548-4562. PMID 2989833 DOI: 10.1073/pnas.82.13.4558  0.71
1984 Bon F, Lebrun E, Gomel J, Rapenbusch RV, Cartaud J, Popot J, Changeux J. Image analysis of the heavy form of the acetylcholine receptor from Torpedo marmorata. Journal of Molecular Biology. 176: 205-237. PMID 6748076 DOI: 10.1016/0022-2836(84)90421-2  0.358
1984 Benoit P, Delhaye-Bouchaud N, Changeux JP, Mariani J. Stability of multiple innervation of Purkinje cells by climbing fibers in the agranular cerebellum of old rats X-irradiated at birth. Brain Research. 316: 310-3. PMID 6467024 DOI: 10.1016/0165-3806(84)90320-1  0.366
1984 Changeux J, Devillers-Thiery A, Chemouilli P. Acetylcholine receptor: an allosteric protein Science. 225: 1335-1345. PMID 6382611 DOI: 10.1126/Science.6382611  0.447
1984 Henderson CE, Huchet M, Changeux JP. Neurite-promoting activities for embryonic spinal neurons and their developmental changes in the chick. Developmental Biology. 104: 336-47. PMID 6378691 DOI: 10.1016/0012-1606(84)90089-7  0.485
1984 Heidmann T, Changeux JP. Time-resolved photolabeling by the noncompetitive blocker chlorpromazine of the acetylcholine receptor in its transiently open and closed ion channel conformations Proceedings of the National Academy of Sciences of the United States of America. 81: 1897-1901. PMID 6324218 DOI: 10.1073/Pnas.81.6.1897  0.387
1984 Popot JL, Changeux JP. Nicotinic receptor of acetylcholine: Structure of an oligomeric integral membrane protein Physiological Reviews. 64: 1162-1239. PMID 6208568  0.3
1983 Henderson CE, Huchet M, Changeux JP. Denervation increases a neurite-promoting activity in extracts of skeletal muscle. Nature. 302: 609-11. PMID 6835393 DOI: 10.1038/302609a0  0.471
1983 Devillers-Thiery A, Giraudat J, Bentaboulet M, Changeux J. Complete mRNA coding sequence of the acetylcholine binding alpha-subunit of Torpedo marmorata acetylcholine receptor: a model for the transmembrane organization of the polypeptide chain Proceedings of the National Academy of Sciences of the United States of America. 80: 2067-2071. PMID 6572962 DOI: 10.1073/Pnas.80.7.2067  0.344
1983 Aslanian D, Heidmann T, Negrerie M, Changeux J. Raman spectroscopy of acetylcholine receptor-rich membranes from Torpedo marmorata and of their isolated components Febs Letters. 164: 393-400. DOI: 10.1016/0014-5793(83)80324-X  0.322
1982 Oswald RE, Changeux JP. Crosslinking of α-bungarotoxin to the acetylcholine receptor from Torpedo marmorata by ultraviolet light irradiation Febs Letters. 139: 225-229. PMID 7075777 DOI: 10.1016/0014-5793(82)80857-0  0.331
1982 Cartaud J, Oswald R, Clément G, Changeux J. Evidence for a skeleton in acetylcholine receptor-rich membranes from Torpedo marmorata electric organ Febs Letters. 145: 250-257. DOI: 10.1016/0014-5793(82)80177-4  0.345
1981 Sobel A, Heidmann T, Cartaud J, Changeux JP. Reconstitution of a functional acetylcholine receptor. Polypeptide chains, ultrastructure, and binding sites for acetylcholine and local anesthetics. European Journal of Biochemistry. 110: 13-33. PMID 7439153 DOI: 10.1111/J.1432-1033.1980.TB04838.X  0.398
1981 Mariani J, Changeux JP. Ontogenesis of olivocerebellar relationships. II. Spontaneous activity of inferior olivary neurons and climbing fibermediated activity of cerebellar Purkinje cells in developing rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 1: 703-9. PMID 7346579  0.406
1981 Mariani J, Changeux JP. Ontogenesis of olivocerebellar relationships. I. Studies by intracellular recordings of the multiple innervation of Purkinje cells by climbing fibers in the developing rat cerebellum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 1: 696-702. PMID 7346578 DOI: 10.1523/Jneurosci.01-07-00696.1981  0.454
1981 Heidmann T, Changeux JP. Stabilization of the high affinity state of the membrane-bound acetylcholine receptor from Torpedo marmorata by noncompetitive blockers. Evidence for dual interaction and pharmacological selectivity Febs Letters. 131: 239-244. PMID 7297675 DOI: 10.1016/0014-5793(81)80375-4  0.352
1981 Oswald R, Changeux JP. Ultraviolet light-induced labeling by noncompetitive blockers of the acetylcholine receptor from Torpedo marmorata Proceedings of the National Academy of Sciences of the United States of America. 78: 3925-3929. PMID 6943590 DOI: 10.1073/Pnas.78.6.3925  0.368
1981 Henderson CE, Huchet M, Changeux JP. Neurite outgrowth from embryonic chicken spinal neurons is promoted by media conditioned by muscle cells. Proceedings of the National Academy of Sciences of the United States of America. 78: 2625-9. PMID 6941315 DOI: 10.1073/Pnas.78.4.2625  0.481
1980 Heidmann T, Changeux JP. Interaction of a fluorescent agonist with the membrane-bound acetylcholine receptor from Torpedo marmorata in the millisecond time range: Resolution of an "intermediate" conformational transition and evidence for positive cooperative effects Biochemical and Biophysical Research Communications. 97: 889-896. PMID 7470156 DOI: 10.1016/0006-291X(80)91460-6  0.346
1980 Cartaud J, Popot J, Changeux J. Light and heavy forms of the acetylcholine receptor from Torpedo marmorata electric organ: Morphological identification using reconstituted vesicles Febs Letters. 121: 327-332. PMID 7461135 DOI: 10.1016/0014-5793(80)80374-7  0.329
1980 Heidmann T, Sobel A, Popot J, Changeux J. Reconstitution of a functional acetylcholine receptor. Conservation of the conformational and allosteric transitions and recovery of the permeability response; role of lipids. Febs Journal. 110: 35-55. PMID 7439162 DOI: 10.1111/J.1432-1033.1980.Tb04839.X  0.412
1980 Heidmann T, Sobel A, Changeux J. Conservation of the kinetic and allosteric properties of the acetylcholine receptor in its Na cholate soluble 9 S form : effect of lipids. Biochemical and Biophysical Research Communications. 93: 127-133. PMID 7378076 DOI: 10.1016/S0006-291X(80)80255-5  0.363
1980 Waksman G, Oswald R, Changeux JP, Roques BP. Synthesis and pharmacological activity on Electrophorus electricus electroplaque of photoaffinity labelling derivatives of the non-competitive blockers di- and tri-methisoquin Febs Letters. 111: 23-28. PMID 7358160 DOI: 10.1016/0014-5793(80)80753-8  0.355
1980 Saitoh T, Oswald R, Wennogle LP, Changeux J. Conditions for the selective labelling of the 66 000 dalton chain of the acetylcholine receptor by the covalent non-competitive blocker 5-azido-[3H]trimethisoquin Febs Letters. 116: 30-36. PMID 6893305 DOI: 10.1016/0014-5793(80)80522-9  0.328
1980 Oswald R, Sobel A, Waksman G, Roques B, Changeux JP. Selective labelling by [3H]trimethisoquin azide of polypeptide chains present in acetylcholine receptor-rich membranes from Torpedo marmorata Febs Letters. 111: 29-34. PMID 6892623 DOI: 10.1016/0014-5793(80)80754-X  0.339
1980 Mariani J, Changeux JP. [Intracellular recordings of the multiple innervation of Purkinje cells by climbing fibers in the cerebellum of the developing rat]. Comptes Rendus Des SéAnces De L'AcadéMie Des Sciences. SéRie D, Sciences Naturelles. 291: 97-100. PMID 6774831  0.371
1980 Saitoh T, Changeux JP. Phosphorylation in vitro of membrane fragments from Torpedo marmorata electric organ. Effect on membrane solubilization by detergents European Journal of Biochemistry. 105: 51-62. PMID 6245881 DOI: 10.1111/J.1432-1033.1980.Tb04473.X  0.32
1980 Mariani J, Changeux JP. Multiple innervation of Purkinje cells by climbing fibers in the cerebellum of the adult staggerer mutant mouse. Journal of Neurobiology. 11: 41-50. PMID 6243692 DOI: 10.1002/Neu.480110106  0.465
1979 Bon C, Changeux J, Jeng T, Fraenkel‐Conrat H. Postsynaptic Effects of Crotoxin and of Its Isolated Subunits Febs Journal. 99: 471-482. PMID 499210 DOI: 10.1111/J.1432-1033.1979.Tb13278.X  0.425
1979 Changeux J, Heidmann T, Popot J, Sobel A. Reconstitution of a functional acetylcholine regulator under defined conditions Febs Letters. 105: 181-187. PMID 488341 DOI: 10.1016/0014-5793(79)80913-8  0.334
1979 Devillers-Thiery A, Changeux J, Paroutaud P, Strosberg AD. The amino-terminal sequence of the 40 000 molecular weight subunit of the acetylcholine receptor protein from Torpedo marmorata Febs Letters. 104: 99-105. PMID 477982 DOI: 10.1016/0014-5793(79)81092-3  0.358
1979 Heidmann T, Changeux JP. Fast kinetic studies on the allosteric interactions between acetylcholine receptor and local anesthetic binding sites European Journal of Biochemistry. 94: 281-296. PMID 436844 DOI: 10.1111/J.1432-1033.1979.Tb12894.X  0.357
1979 Heidmann T, Changeux JP. Fast kinetic studies on the interaction of a fluorescent agonist with the membrane-bound acetylcholine receptor from Torpedo marmorata European Journal of Biochemistry. 94: 255-279. PMID 436843 DOI: 10.1111/J.1432-1033.1979.Tb12893.X  0.38
1979 Betz H, Changeux JP. Regulation of muscle acetylcoline receptor synthesis in vitro by cyclic nucleotide derivatives [20] Nature. 278: 749-752. PMID 219375 DOI: 10.1038/278749a0  0.541
1979 Saitoh T, Wennogle LP, Changeux J. Factors regulating the susceptibility of the acetylcholine receptor protein to heat inactivation. Febs Letters. 108: 489-494. PMID 42563 DOI: 10.1016/0014-5793(79)80595-5  0.323
1978 Changeux JP, Mikoshiba K. Genetic and 'Epigenetic' Factors Regulating Synapse Formation in Vertebrate Cerebellum and Neuromuscular Junction Progress in Brain Research. 48: 43-66. PMID 746166 DOI: 10.1016/S0079-6123(08)61015-8  0.319
1978 Bourgeois J, Popot J, Ryter A, Changeux J. Quantitative studies on the localization of the cholinergic receptor protein in the normal and denervated electroplaque from Electrophorus electricus. Journal of Cell Biology. 79: 200-216. PMID 701372 DOI: 10.1083/Jcb.79.1.200  0.375
1978 Popot JL, Demel RA, Sobel A, Van Deenen LL, Changeux JP. Interaction of the acetylcholine (nicotinic) receptor protein from Torpedo marmorata electric organ with monolayers of pure lipids. European Journal of Biochemistry / Febs. 85: 27-42. PMID 639821 DOI: 10.1111/j.1432-1033.1978.tb12209.x  0.361
1978 Heidmann T, Sobel A, Changeux J. Recovery of allosteric interactions between a fluorescent cholinergic agonist and local anesthetics after removal of the detergent from cholate-solubilized membrane fragments rich in acetylcholine receptor Febs Letters. 94: 397-404. PMID 568082 DOI: 10.1016/0014-5793(78)80986-7  0.364
1978 Briley MS, Changeux JP. Recovery of some functional properties of the detergent-extracted cholinergic receptor protein from Torpedo marmorata after reintegration into a membrane environment European Journal of Biochemistry. 84: 429-439. PMID 565286 DOI: 10.1111/J.1432-1033.1978.Tb12184.X  0.403
1978 Merlie JP, Changeux JP, Gros F. Skeletal muscle acetylcholine receptor. Purification, characterization, and turnover in muscle cell cultures. The Journal of Biological Chemistry. 253: 2882-91. PMID 564910  0.582
1978 Heidmann T, Changeux JP. Structural and functional properties of the acetylcholine receptor protein in its purified and membrane-bound states Annual Review of Biochemistry. 47: 317-357. PMID 354498 DOI: 10.1146/Annurev.Bi.47.070178.001533  0.34
1977 Sobel A, Weber M, Changeux J. Large-scale purification of the acetylcholine-receptor protein in its membrane-bound and detergent-extracted forms from Torpedo marmorata electric organ. Febs Journal. 80: 215-224. PMID 923574 DOI: 10.1111/J.1432-1033.1977.Tb11874.X  0.371
1977 Sobel A, Changeux JP. Purification and characterization of the cholinergic receptor protein in its membrane bound and detergent soluble forms from the electric organ of Torpedo marmorata Biochemical Society Transactions. 5: 511-514. PMID 902870 DOI: 10.1042/Bst0050511  0.353
1977 Betz H, Bourgeois J, Changeux J. Evidence for degradation of the acetylcholine (nicotinic) receptor in skeletal muscle during the development of the chick embryo Febs Letters. 77: 219-224. PMID 862921 DOI: 10.1016/0014-5793(77)80238-X  0.565
1977 Bon C, Changeux JP. Ceruleotoxin: a possible marker of the cholinergic ionophore European Journal of Biochemistry. 74: 43-51. PMID 856574 DOI: 10.1111/J.1432-1033.1977.Tb11364.X  0.44
1977 Teichberg VI, Sobel A, Changeux JP. In vitro phosphorylation of the acetylcholine receptor. Nature. 267: 540-2. PMID 559948 DOI: 10.1038/267540a0  0.622
1977 Briley MS, Changeux JP. Isolation and purification of the nicotinic acetylcholine receptor and its functional reconstitution into a membrane environment International Review of Neurobiology. 20: 31-63. PMID 338528 DOI: 10.1016/S0074-7742(08)60650-9  0.42
1977 Teichberg VI, Changeux JP. Evidence for protein phosphorylation and dephosphorylation in membrane fragments isolated from the electric organ of Electrophorus electricus. Febs Letters. 74: 71-6. PMID 190043 DOI: 10.1016/0014-5793(77)80755-2  0.576
1977 Mariani J, Crepel F, Mikoshiba K, Changeux JP, Sotelo C. Anatomical, physiological and biochemical studies of the cerebellum from Reeler mutant mouse. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 281: 1-28. PMID 22882 DOI: 10.1098/Rstb.1977.0121  0.404
1977 Atlas D, Teichberg VI, Changeux JP. Direct evidence for beta-adrenoreceptors on the Purkinje cells of mouse cerebellum. Brain Research. 128: 532-6. PMID 18258 DOI: 10.1016/0006-8993(77)90178-0  0.511
1976 Merlie JP, Changeux JP, Gros F. Acetylcholine receptor degradation measured by pulse chase labelling. Nature. 264: 74-6. PMID 1004540 DOI: 10.1038/264074A0  0.667
1976 Grünhagen HH, Changeux JP. Studies on the electrogenic action of acetylcholine with Torpedo marmorata electric organ. V. Qualitative correlation between pharmacological effects and equilibration processes of the cholinergic receptor protein as revealed by the structural probe quinacrine Journal of Molecular Biology. 106: 517-535. PMID 978734 DOI: 10.1016/0022-2836(76)90250-3  0.333
1976 Grünhagen HH, Changeux JP. Studies on the electrogenic action of acetylcholine with Torpedo marmorata electric organ. IV. Quinacrine: a fluorescent probe for the conformational transitions of the cholinergic receptor protein in its membrane-bound state Journal of Molecular Biology. 106: 497-516. PMID 978733 DOI: 10.1016/0022-2836(76)90249-7  0.339
1976 Sugiyama H, Popot JL, Changeux JP. Studies on the electrogenic action of acetylcholine with Torpedo marmorata electric organ. III. Pharmocological desensitization in vitro of the receptor-rich membrane fragments by cholinergic agonists. Journal of Molecular Biology. 106: 485-96. PMID 978732 DOI: 10.1016/0022-2836(76)90248-5  0.521
1976 Popot JL, Sugiyama H, Changeux JP. Studies on the electrogenic action of acetylcholine with Torpedo marmorata electric organ. II. The permeability response of the receptor-rich membrane fragments to cholinergic agonists in vitro. Journal of Molecular Biology. 106: 469-83. PMID 978731 DOI: 10.1016/0022-2836(76)90247-3  0.555
1976 Moreau M, Changeux JP. Studies on the electrogenic action of acetylcholine with Torpedo marmorata electric organ. I. Pharmacological properties of the electroplaque Journal of Molecular Biology. 106: 457-467. PMID 978730 DOI: 10.1016/0022-2836(76)90246-1  0.308
1976 Waksman G, Fournié-Zaluski MC, Roques B, Heidmann T, Grünhagen HH, Changeux JP. Synthesis of fluorescent acyl-cholines with agonistic properties: pharmacological activity on Electrophorus electroplaque and interaction in vitro with Torpedo receptor-rich membrane fragments Febs Letters. 67: 335-342. PMID 964367 DOI: 10.1016/0014-5793(76)80560-1  0.354
1976 Teichberg VI, Changeux JP. Presence of two forms of acetylcholine receptor with different isoelectric points in the electric organ of Electrophorus electricus and their catalytic interconversion in vitro. Febs Letters. 67: 264-8. PMID 964359 DOI: 10.1016/0014-5793(76)80543-1  0.626
1975 Bon C, Changeux JP. Ceruleotoxin: An acidic neurotoxin from the venom of Bungarus caeruleus which blocks the response to a cholinergic agonist without binding to the cholinergic receptor site Febs Letters. 59: 212-216. PMID 1241677 DOI: 10.1016/0014-5793(75)80377-2  0.442
1975 Lester HA, Changeux JP, Sheridan RE. Conductance increases produced by bath application of cholinergic agonists to Electrophorus electroplaques. The Journal of General Physiology. 65: 797-816. PMID 1194885 DOI: 10.1085/Jgp.65.6.797  0.495
1975 Sugiyama H, Changeux JP. Interconversion between different states of affinity for acetylcholine of the cholinergic receptor protein from Torpedo marmorata European Journal of Biochemistry. 55: 505-515. PMID 1175609 DOI: 10.1111/J.1432-1033.1975.Tb02188.X  0.532
1975 Cohen JB, Changeux JP. The cholinergic receptor protein in its membrane environment. Annual Review of Pharmacology. 15: 83-103. PMID 1096798 DOI: 10.1146/annurev.pa.15.040175.000503  0.436
1975 Merlie JP, Sobel A, Changeux JP, Gros F. Synthesis of acetylcholine receptor during differentiation of cultured embryonic muscle cells. Proceedings of the National Academy of Sciences of the United States of America. 72: 4028-32. PMID 1060086 DOI: 10.1073/Pnas.72.10.4028  0.696
1975 Brisson AD, Scandella CJ, Bienvenüe A, Devaux PF, Cohen JB, Changeux JP. Interaction of a spin-labeled long chain acylcholine with the cholinergic receptor protein in its membrane environment. Proceedings of the National Academy of Sciences of the United States of America. 72: 1087-91. PMID 165483  0.414
1974 Cohen JB, Weber M, Changeux JP. Effects of local anesthetics and calcium on the interaction of cholinergic ligands with the nicotinic receptor protein from Torpedo marmorata. Molecular Pharmacology. 10: 904-32. PMID 25771543  0.483
1974 Dupont Y, Cohen JB, Changeux JP. X-ray diffraction study of membrane fragments rich in acetylcholine receptor protein prepared from the electric organ of Torpedo marmorata. Febs Letters. 40: 130-3. PMID 4855432 DOI: 10.1016/0014-5793(74)80910-5  0.472
1974 Meunier JC, Sealock R, Olsen R, Changeux JP. Purification and properties of the cholinergic receptor protein from Electrophorus electricus electric tissue. European Journal of Biochemistry / Febs. 45: 371-94. PMID 4853969  0.507
1974 Hazelbauer GL, Changeux JP. Reconstitution of a chemically excitable membrane Proceedings of the National Academy of Sciences of the United States of America. 71: 1479-1483. PMID 4524651 DOI: 10.1073/Pnas.71.4.1479  0.615
1974 Cohen JB, Weber M, Changeux JP. [Effect of local anesthetics on the binding properties of cholinergic receptors of the torpedo]. Comptes Rendus Hebdomadaires Des Sã©Ances De L'Acadã©Mie Des Sciences. Sã©Rie D: Sciences Naturelles. 278: 1269-72. PMID 4276961  0.46
1974 Crepel F, Mariani J, Korn H, Changeux JP. [Electrophysiology of the cerebellar cortex in the staggerer mutant mouse]. Comptes Rendus Hebdomadaires Des Sã©Ances De L'Acadã©Mie Des Sciences. Sã©Rie D: Sciences Naturelles. 277: 2761-3. PMID 4211422  0.376
1974 Gerschenfeld HM, Gros F, Jacob F, Lwoff A, Changeux JP, Masle, Wall P. Academics in Chile [1] Nature. 248: 376. DOI: 10.1038/248376a0  0.493
1973 Hucho F, Changeux JP. Molecular weight and quaternary structure of the cholinergic receptor protein extracted by detergents from Electrophorus electricus electric tissue. Febs Letters. 38: 11-5. PMID 4772687 DOI: 10.1016/0014-5793(73)80500-9  0.498
1973 Cohen JB, Changeux JP. Interaction of a fluorescent ligand with membrane-bound cholinergic receptor from Torpedo marmorata. Biochemistry. 12: 4855-64. PMID 4761972 DOI: 10.1021/Bi00748A008  0.414
1973 Cohen JB, Changeux JP. [Interaction of a fluorescent ligand with the protein receptor of acetylcholine present in Torpedo marmorata membrane fragments]. Comptes Rendus Hebdomadaires Des Sã©Ances De L'Acadã©Mie Des Sciences. Sã©Rie D: Sciences Naturelles. 277: 603-6. PMID 4205999  0.425
1973 Sugiyama H, Benda P, Meunier JC, Changeux JP. Immunological characterisation of the cholinergic receptor protein from Electrophorus electricus. Febs Letters. 35: 124-8. PMID 4201666 DOI: 10.1016/0014-5793(73)80592-7  0.672
1973 Meunier JC, Changeux JP. Comparison between the affinities for reversible cholinergic ligands of a purified and membrane bound state of the acetylcholine-receptor protein from Electrophorus electricus Febs Letters. 32: 143-148. PMID 4146034 DOI: 10.1016/0014-5793(73)80758-6  0.388
1973 Cartaud J, Benedetti EL, Cohen JB, Meunier JC, Changeux JP. Presence of a lattice structure in membrane fragments rich in nicotinic receptor protein from the electric organ of Torpedo marmorata. Febs Letters. 33: 109-13. PMID 4124671 DOI: 10.1016/0014-5793(73)80171-1  0.535
1972 Bourgeois J, Ryter A, Menez A, Fromageot P, Boquet P, Changeux J. Localization of the cholinergic receptor protein in Electrophorus electroplax by high resolution autoradiography Febs Letters. 25: 127-133. PMID 11946736 DOI: 10.1016/0014-5793(72)80469-1  0.336
1972 Meunier JC, Olsen RW, Changeux JP. Studies on the cholinergic receptor protein from Electrophorus electricus. Effect of detergents on some hydrodynamic properties of the receptor protein in solution. Febs Letters. 24: 63-8. PMID 5086619  0.527
1972 Meunier JC, Olsen RW, Menez A, Fromageot P, Boquet P, Changeux JP. Some physical properties of the cholinergic receptor protein from Electrophorus electricus revealed by a tritiated alpha-toxin from Naja nigricollis venom. Biochemistry. 11: 1200-10. PMID 5012974 DOI: 10.1021/Bi00757A014  0.545
1972 Olsen RW, Meunier JC, Changeux JP. Progress in the purification of the cholinergic receptor protein from Electrophorus electricus by affinity chromatography. Febs Letters. 28: 96-100. PMID 4646881 DOI: 10.1016/0014-5793(72)80686-0  0.598
1972 Cohen JB, Weber M, Huchet M, Changeux JP. Purification from Torpedo marmorata electric tissue of membrane fragments particularly rich in cholinergic receptor protein. Febs Letters. 26: 43-7. PMID 4636749 DOI: 10.1016/0014-5793(72)80538-6  0.515
1971 Meunier JC, Olsen R, Menez A, Morgat JL, Fromageot P, Ronseray AM, Boquet P, Changeux JP. [Some physical properties of the acetylcholine protein receptor studied with a radioactive neurotoxin]. Comptes Rendus Hebdomadaires Des SéAnces De L'AcadéMie Des Sciences. SéRie D: Sciences Naturelles. 273: 595-8. PMID 5001139  0.525
1971 Kasai M, Changeux JP. In vitro excitation of purified membrane fragments by cholinergic agonists - III. Comparison of the dose-response curves to decamethonium with the corresponding binding curves of decamethonium to the cholinergic receptor The Journal of Membrane Biology. 6: 58-80. DOI: 10.1007/BF01874114  0.383
1971 Kasai M, Changeux JP. In Vitro excitation of purified membrane fragments by cholinergic agonists - I. Pharmalogical properties of the excitable membrane fragments The Journal of Membrane Biology. 6: 1-23. DOI: 10.1007/BF01874112  0.326
1970 Bauman A, Changeux J, Benda P, Huchet M. Purification of membrane fragments derived from the non excitable surface of the eel electroplax. Febs Letters. 8: 145-148. PMID 11947555 DOI: 10.1016/0014-5793(70)80248-4  0.524
1970 Changeux J, Kasai M, Lee C. Use of a Snake Venom Toxin to Characterize the Cholinergic Receptor Protein Proceedings of the National Academy of Sciences of the United States of America. 67: 1241-1247. PMID 5274453 DOI: 10.1073/Pnas.67.3.1241  0.401
1970 Benda P, Tsuji S, Daussant J, Changeux JP. Localization of acetylcholinesterase by immunofluorescence in eel electroplax. Nature. 225: 1149-50. PMID 4984866 DOI: 10.1038/2251149a0  0.544
1969 Changeux JP, Podleski T, Meunier JC. On Some Structural Analogies between Acetylcholinesterase and the Macromolecular Receptor of Acetylcholine. The Journal of General Physiology. 54: 225-44. PMID 19873643 DOI: 10.1085/JGP.54.1.225  0.409
1969 Podleski T, Meunier JC, Changeux JP. Compared effects of dithiotreitol on the interaction of an affinity-labeling reagent with acetylcholinesterase and the excitable membrane of the electroplax. Proceedings of the National Academy of Sciences of the United States of America. 63: 1239-46. PMID 5260926 DOI: 10.1073/Pnas.63.4.1239  0.368
1969 Meunier JC, Changeux JP. On the irreversible binding of p-(trimethylammonium) benzenediazonium fluoroborate (TDF) to acetylcholinesterase from electrogenic tissue Febs Letters. 2: 224-226. DOI: 10.1016/0014-5793(69)80025-6  0.318
1968 Changeux J, Leuzinger W, Huchet M. Specific binding of acetylcholine to acetylcholinesterase in the presence of eserine. Febs Letters. 2: 77-80. PMID 11946273 DOI: 10.1016/0014-5793(68)80105-X  0.367
1967 Changeux JP, Podleski TR, Wofsy L. Affinity labeling of the acetylcholine-receptor. Proceedings of the National Academy of Sciences of the United States of America. 58: 2063-70. PMID 5237500 DOI: 10.1073/Pnas.58.5.2063  0.392
1965 MONOD J, WYMAN J, CHANGEUX JP. ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL. Journal of Molecular Biology. 12: 88-118. PMID 14343300 DOI: 10.1016/S0022-2836(65)80285-6  0.713
1963 MONOD J, CHANGEUX JP, JACOB F. Allosteric proteins and cellular control systems. Journal of Molecular Biology. 6: 306-29. PMID 13936070 DOI: 10.1016/S0022-2836(63)80091-1  0.706
Low-probability matches (unlikely to be authored by this person)
2001 Altiok N, Changeux JP. Electrical activity regulates AChR gene expression via JNK, PKCzeta and Sp1 in skeletal chick muscle. Febs Letters. 487: 333-8. PMID 11163354 DOI: 10.1016/S0014-5793(00)02311-5  0.299
1974 Mallet J, Huchet M, Shelanski M, Changeux J. Protein differences associated with the absence of granule cells in the cerebella from the mutant weaver mouse and from X-irradiated rat Febs Letters. 46: 243-246. PMID 4419600 DOI: 10.1016/0014-5793(74)80378-9  0.299
2014 Sauguet L, Shahsavar A, Poitevin F, Huon C, Menny A, Nemecz A, Haouz A, Changeux J, Corringer P, Delarue M. X-Ray Structures of the Open and Resting Forms of the Same Bacterial Pentameric Ligand-Gated Ion Channel Biophysical Journal. 106: 641a. DOI: 10.1016/J.Bpj.2013.11.3551  0.298
2009 Suarez SV, Amadon A, Giacomini E, Wiklund A, Changeux JP, Le Bihan D, Granon S. Brain activation by short-term nicotine exposure in anesthetized wild-type and beta2-nicotinic receptors knockout mice: a BOLD fMRI study. Psychopharmacology. 202: 599-610. PMID 18818904 DOI: 10.1007/S00213-008-1338-X  0.298
2016 Changeux JP, Christopoulos A. Allosteric Modulation as a Unifying Mechanism for Receptor Function and Regulation. Cell. 166: 1084-102. PMID 27565340 DOI: 10.1016/j.cell.2016.08.015  0.295
2000 Paas-Rozner M, Dayan M, Paas Y, Changeux JP, Wirguin I, Sela M, Mozes E. Oral administration of a dual analog of two myasthenogenic T cell epitopes down-regulates experimental autoimmune myasthenia gravis in mice. Proceedings of the National Academy of Sciences of the United States of America. 97: 2168-73. PMID 10681457 DOI: 10.1073/Pnas.040554597  0.294
1973 Changeux JP. Cholinergic receptors in Electrophorus Neurosciences Research Program Bulletin. 11: 246-252. PMID 4716596  0.293
1996 Yu D, Zhang L, Eiselé JL, Bertrand D, Changeux JP, Weight FF. Ethanol inhibition of nicotinic acetylcholine type alpha 7 receptors involves the amino-terminal domain of the receptor. Molecular Pharmacology. 50: 1010-6. PMID 8863848  0.293
1976 Changeux JP, Danchin A. Selective stabilisation of developing synapses as a mechanism for the specification of neuronal networks Nature. 264: 705-712. PMID 189195 DOI: 10.1038/264705a0  0.292
2004 Pons S, Sallette J, Bourgeois JP, Taly A, Changeux JP, Devillers-Thiéry A. Critical role of the C-terminal segment in the maturation and export to the cell surface of the homopentameric alpha 7-5HT3A receptor. The European Journal of Neuroscience. 20: 2022-30. PMID 15450081 DOI: 10.1111/j.1460-9568.2004.03673.x  0.292
2001 Salmon AM, Damaj MI, Marubio LM, Epping-Jordan MP, Merlo-Pich E, Changeux JP. Altered neuroadaptation in opiate dependence and neurogenic inflammatory nociception in alpha CGRP-deficient mice. Nature Neuroscience. 4: 357-8. PMID 11276224 DOI: 10.1038/86001  0.29
1996 Le Novère N, Zoli M, Changeux JP. Neuronal nicotinic receptor alpha 6 subunit mRNA is selectively concentrated in catecholaminergic nuclei of the rat brain. The European Journal of Neuroscience. 8: 2428-39. PMID 8950106  0.29
1999 Gramolini AO, Angus LM, Schaeffer L, Burton EA, Tinsley JM, Davies KE, Changeux JP, Jasmin BJ. Induction of utrophin gene expression by heregulin in skeletal muscle cells: role of the N-box motif and GA binding protein. Proceedings of the National Academy of Sciences of the United States of America. 96: 3223-7. PMID 10077665 DOI: 10.1073/Pnas.96.6.3223  0.289
1980 Wennogle LP, Changeux JP. Transmembrane orientation of proteins present in acetylcholine receptor-rich membranes from Torpedo marmorata studied by selective proteolysis European Journal of Biochemistry. 106: 381-393. PMID 6772438 DOI: 10.1111/J.1432-1033.1980.Tb04584.X  0.289
1996 Changeux JP, Bessis A, Bourgeois JP, Corringer PJ, Devillers-Thiery A, Eiselé JL, Kerszberg M, Léna C, Le Novère N, Picciotto M, Zoli M. Nicotinic receptors and brain plasticity. Cold Spring Harbor Symposia On Quantitative Biology. 61: 343-62. PMID 9246464  0.288
2014 Holton B, Tzartos SJ, Changeux JP. Comparison of embryonic and adult torpedo acetylcholine receptor by sedimentation characteristics and antigenicity. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 2: 549-55. PMID 24874395 DOI: 10.1016/0736-5748(84)90032-7  0.287
2000 Rogner UC, Spyropoulos DD, Le Novère N, Changeux JP, Avner P. Control of neurulation by the nucleosome assembly protein-1-like 2. Nature Genetics. 25: 431-5. PMID 10932189 DOI: 10.1038/78124  0.286
1993 Kerszberg M, Changeux J. A Model for Motor Endplate Morphogenesis: Diffusible Morphogens, Transmembrane Signaling, and Compartmentalized Gene Expression Neural Computation. 5: 341-358. DOI: 10.1162/neco.1993.5.3.341  0.285
2013 Changeux JP. The concept of allosteric modulation: an overview. Drug Discovery Today. Technologies. 10: e223-8. PMID 24050272 DOI: 10.1016/j.ddtec.2012.07.007  0.285
1995 Legay C, Huchet M, Massoulié J, Changeux JP. Developmental regulation of acetylcholinesterase transcripts in the mouse diaphragm: alternative splicing and focalization. The European Journal of Neuroscience. 7: 1803-9. PMID 7582132 DOI: 10.1111/J.1460-9568.1995.Tb00699.X  0.284
1969 Changeux JP, Ryter A, Leuzinger W, Barrand P, Podleski T. On the association of tyrocidine with acetylcholinesterase. Proceedings of the National Academy of Sciences of the United States of America. 62: 986-93. PMID 5257018 DOI: 10.1073/Pnas.62.3.986  0.284
1977 Bon C, Changeux JP. Chemical and pharmacological characterization of toxic polypeptides from the venom of Bungarus caeruleus European Journal of Biochemistry. 74: 31-42. PMID 856573 DOI: 10.1111/J.1432-1033.1977.Tb11363.X  0.283
1966 Rubin MM, Changeux JP. On the nature of allosteric transitions: Implications of non-exclusive ligand binding Journal of Molecular Biology. 21: 265-274. PMID 5972463 DOI: 10.1016/0022-2836(66)90097-0  0.283
1981 Oswald RE, Changeux JP. Selective labeling of the δ subunit of the acetylcholine receptor by a covalent local anesthetic Biochemistry. 20: 7166-7174. PMID 6895603 DOI: 10.1021/bi00528a018  0.283
2008 Pons S, Fattore L, Cossu G, Tolu S, Porcu E, McIntosh JM, Changeux JP, Maskos U, Fratta W. Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12318-27. PMID 19020025 DOI: 10.1523/Jneurosci.3918-08.2008  0.282
2007 Skok MV, Grailhe R, Agenes F, Changeux JP. The role of nicotinic receptors in B-lymphocyte development and activation. Life Sciences. 80: 2334-6. PMID 17363009 DOI: 10.1016/j.lfs.2007.02.005  0.281
1981 Saitoh T, Changeux JP. Change in state of phosphorylation of acetylcholine receptor during maturation of the electromotor synapse in Torpedo marmorata electric organ Proceedings of the National Academy of Sciences of the United States of America. 78: 4430-4434. PMID 6945595 DOI: 10.1073/Pnas.78.7.4430  0.28
2016 Evers K, Changeux JP. Proactive epigenesis and ethical innovation: A neuronal hypothesis for the genesis of ethical rules. Embo Reports. PMID 27613656 DOI: 10.15252/embr.201642783  0.279
1999 Arroyo-Jim nez MM, Bourgeois JP, Marubio LM, Le Sourd AM, Ottersen OP, Rinvik E, Fairén A, Changeux JP. Ultrastructural localization of the alpha4-subunit of the neuronal acetylcholine nicotinic receptor in the rat substantia nigra. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6475-87. PMID 10414976  0.279
2014 Kaczanowska K, Harel M, Radić Z, Changeux JP, Finn MG, Taylor P. Structural basis for cooperative interactions of substituted 2-aminopyrimidines with the acetylcholine binding protein. Proceedings of the National Academy of Sciences of the United States of America. 111: 10749-54. PMID 25006260 DOI: 10.1073/Pnas.1410992111  0.278
2002 Shoaib M, Gommans J, Morley A, Stolerman IP, Grailhe R, Changeux JP. The role of nicotinic receptor beta-2 subunits in nicotine discrimination and conditioned taste aversion. Neuropharmacology. 42: 530-9. PMID 11955523 DOI: 10.1016/S0028-3908(01)00194-0  0.278
2004 Schütz B, Mauer D, Salmon AM, Changeux JP, Zimmer A. Analysis of the cellular expression pattern of beta-CGRP in alpha-CGRP-deficient mice. The Journal of Comparative Neurology. 476: 32-43. PMID 15236465 DOI: 10.1002/Cne.20211  0.277
2013 Changeux JP. The origins of allostery: from personal memories to material for the future. Journal of Molecular Biology. 425: 1396-406. PMID 23523086 DOI: 10.1016/j.jmb.2013.02.033  0.276
1983 Changeux JP. Concluding Remarks: On the "Singularity" of Nerve Cells and its Ontogenesis Progress in Brain Research. 58: 465-478. PMID 6635204 DOI: 10.1016/S0079-6123(08)60049-7  0.276
2015 Changeux JP, Corringer PJ, Maskos U. The nicotinic acetylcholine receptor: From molecular biology to cognition. Neuropharmacology. 96: 135-6. PMID 25842243 DOI: 10.1016/j.neuropharm.2015.03.024  0.275
1975 Mallet J, Huchet M, Pougeois R, Changeux J. A protein difference associated with defects of the Purkinje cell in staggerer and nervous mutant mice. Febs Letters. 52: 216-220. PMID 1132476 DOI: 10.1016/0014-5793(75)80809-X  0.273
1962 CHANGEUX JP. Effect of L-threonine and L-isoleucine analogs on L-threonine desaminase Journal of Molecular Biology. 4: 220-225. PMID 13878123 DOI: 10.1016/S0022-2836(62)80054-0  0.273
2019 Menez A, Morgat J, Fromageot P, Ronseray A, Boquet P, Changeux J. Tritium labelling of the alpha-neurotoxin of Naja nigricollis. Febs Letters. 17: 333-335. PMID 11946062 DOI: 10.1016/0014-5793(71)80180-1  0.272
2014 Sauguet L, Shahsavar A, Poitevin F, Huon C, Menny A, nemecz a, Haouz A, Changeux J, Corringer P, Delarue M. Structural Basis for Allosteric Transitions in the GLIC Pentameric Proton-Gated Ion Channel Biophysical Journal. 106: 343a. DOI: 10.1016/J.Bpj.2013.11.1960  0.272
2008 Putz G, Kristufek D, Orr-Urtreger A, Changeux JP, Huck S, Scholze P. Nicotinic acetylcholine receptor-subunit mRNAs in the mouse superior cervical ganglion are regulated by development but not by deletion of distinct subunit genes. Journal of Neuroscience Research. 86: 972-81. PMID 17975828 DOI: 10.1002/jnr.21559  0.271
1999 Bertrand D, Changeux JP. Nicotinic receptor: a prototype of allosteric ligand-gated ion channels and its possible implications in epilepsy. Advances in Neurology. 79: 171-88. PMID 10514813  0.271
1986 Changeux JP. Chapter 26 Coexistence of neuronal messengers and molecular selection Progress in Brain Research. 68: 373-403. PMID 2882560 DOI: 10.1016/S0079-6123(08)60252-6  0.27
1970 Blumenthal R, Changeux JP. About the changes of internal ionic concentration in the isolated electroplax during chemical excitation Bba - Biomembranes. 219: 398-404. PMID 5497198 DOI: 10.1016/0005-2736(70)90217-8  0.27
2020 Oasa S, Vukojević V, Rigler R, Tsigelny IF, Changeux JP, Terenius L. A strategy for designing allosteric modulators of transcription factor dimerization. Proceedings of the National Academy of Sciences of the United States of America. PMID 31953259 DOI: 10.1073/Pnas.1915531117  0.27
2006 Besson M, David V, Suarez S, Cormier A, Cazala P, Changeux JP, Granon S. Genetic dissociation of two behaviors associated with nicotine addiction: beta-2 containing nicotinic receptors are involved in nicotine reinforcement but not in withdrawal syndrome. Psychopharmacology. 187: 189-99. PMID 16752141 DOI: 10.1007/S00213-006-0418-Z  0.269
1969 Kasai M, Changeux JP, Monnerie L. In vitro interaction of 1-anilino 8 naphthalene sulfonate with excitable membranes isolated from the electric organ of Electrophorus electricus. Biochemical and Biophysical Research Communications. 36: 420-7. PMID 5822399 DOI: 10.1016/0006-291X(69)90581-6  0.269
1995 Jasmin BJ, Antony C, Changeux JP, Cartaud J. Nerve-dependent plasticity of the Golgi complex in skeletal muscle fibres: compartmentalization within the subneural sarcoplasm. The European Journal of Neuroscience. 7: 470-9. PMID 7773444 DOI: 10.1111/J.1460-9568.1995.Tb00343.X  0.268
2003 Sunesen M, Changeux JP. Transcription in neuromuscular junction formation: who turns on whom? Journal of Neurocytology. 32: 677-84. PMID 15034260 DOI: 10.1023/B:NEUR.0000020616.53664.80  0.268
1972 Changeux JP. Studies on the molecular mechanism of the response of an excitable membrane to cholinergic agents Chemistry and Physics of Lipids. 8: 355-365. PMID 4557529 DOI: 10.1016/0009-3084(72)90066-7  0.265
1971 Kasai M, Changeux JP. In Vitro excitation of purified membrane fragments by cholinergic agonists - II. The permeability change caused by cholinergic agonists The Journal of Membrane Biology. 6: 24-57. DOI: 10.1007/BF01874113  0.265
1998 Kerszberg M, Changeux JP. A simple molecular model of neurulation. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 20: 758-70. PMID 9819565 DOI: 10.1002/(SICI)1521-1878(199809)20:9<758::AID-BIES9>3.0.CO;2-C  0.265
1977 Grünhagen H, Iwatsubo M, Changeux J. Fast Kinetic Studies on the Interaction of Cholinergic Agonists with the Membrane-Bound Acetylcholine Receptor from Torpedo marmorata as Revealed by Quinacrine Fluorescence Febs Journal. 80: 225-242. PMID 923575 DOI: 10.1111/J.1432-1033.1977.Tb11875.X  0.265
1976 Kato G, Changeux JP. Studies on the effect of histrionicotoxin on the monocellular electroplax from Electrophorus electricus on the ending of [3H]acetylcholine to membrane fragments from Torpedo marmorata Molecular Pharmacology. 12: 92-100. PMID 1256447  0.264
1970 Kasai M, Podleski TR, Changeux J. Some structural properties of excitable membranes labelled by fluorescent probes. Febs Letters. 7: 13-19. PMID 11947418 DOI: 10.1016/0014-5793(70)80605-6  0.264
2018 Farisco M, Evers K, Changeux JP. Drug Addiction: From Neuroscience to Ethics. Frontiers in Psychiatry. 9: 595. PMID 30524319 DOI: 10.3389/fpsyt.2018.00595  0.263
1979 Woodhams P, Mallet J, Changeux JP, Balázs R. Immunological studies on the Purkinje cells from rat and mouse cerebella. II. Immunohistochemical specificity of the antiserum to purkinje cells. Developmental Biology. 72: 320-6. PMID 116895 DOI: 10.1016/0012-1606(79)90121-0  0.26
2011 Changeux JP, Lou HC. Emergent pharmacology of conscious experience: new perspectives in substance addiction. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2098-108. PMID 21719514 DOI: 10.1096/fj.11-0702ufm  0.26
1968 Changeux JP. Allosteric interactions in aspartate transcarbamylase. III. Interpretation of experimental data in terms of the model of monod, wyman, and changeux Biochemistry. 7: 553-561. PMID 4868541 DOI: 10.1021/Bi00842A601  0.259
1993 Benoit P, Changeux JP. Voltage dependencies of the effects of chlorpromazine on the nicotinic receptor channel from mouse muscle cell line So18. Neuroscience Letters. 160: 81-4. PMID 7504221 DOI: 10.1016/0304-3940(93)90918-B  0.259
2002 Fischer M, Haase I, Feicht R, Richter G, Gerhardt S, Changeux JP, Huber R, Bacher A. Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe. European Journal of Biochemistry / Febs. 269: 519-26. PMID 11856310 DOI: 10.1046/J.0014-2956.2001.02674.X  0.258
1976 Mallet J, Huchet M, Pougeois R, Changeux J. Anatomical physiological and biochemical studies on the cerebellum from mutant mice. Iii. Protein differences associated with the weaver, staggerer and nervous mutations. Brain Research. 103: 291-312. PMID 1252920 DOI: 10.1016/0006-8993(76)90800-3  0.258
1980 Mikoshiba K, Huchet M, Changeux JP. Biochemical and immunological studies on the P400 protein, a protein characteristic of the Purkinje cell from mouse and rat cerebellum. Developmental Neuroscience. 2: 254-75. PMID 121073 DOI: 10.1159/000112489  0.258
2002 de Kerchove D'Exaerde A, Cartaud J, Ravel-Chapuis A, Seroz T, Pasteau F, Angus LM, Jasmin BJ, Changeux JP, Schaeffer L. Expression of mutant Ets protein at the neuromuscular synapse causes alterations in morphology and gene expression. Embo Reports. 3: 1075-81. PMID 12393756 DOI: 10.1093/Embo-Reports/Kvf220  0.256
1995 Antony C, Huchet M, Changeux JP, Cartaud J. Developmental regulation of membrane traffic organization during synaptogenesis in mouse diaphragm muscle. The Journal of Cell Biology. 130: 959-68. PMID 7642711 DOI: 10.1083/Jcb.130.4.959  0.256
2020 Lou HC, Rømer Thomsen K, Changeux JP. The Molecular Organization of Self-awareness: Paralimbic Dopamine-GABA Interaction. Frontiers in Systems Neuroscience. 14: 3. PMID 32047425 DOI: 10.3389/fnsys.2020.00003  0.255
2011 Changeux JP. 50th anniversary of the word "allosteric". Protein Science : a Publication of the Protein Society. 20: 1119-24. PMID 21574197 DOI: 10.1002/pro.658  0.255
1979 Changeux JP. The acetylcholine receptor: an "allosteric" membrane protein Harvey Lectures. 75: 85-254. PMID 400609  0.253
1979 Mallet J, Christen R, Changeux J. Immunological studies on the Purkinje cells from rat and mouse cerebella. I. Evidence for antibodies characteristic of the Purkinje cells. Developmental Biology. 72: 308-319. PMID 92429 DOI: 10.1016/0012-1606(79)90120-9  0.252
2015 Sekiguchi H, Matsushita Y, Nishino Y, Ikezaki K, Miyazawa A, Yagi N, Huron C, Changeux J, Corringer P, Sasaki YC. Single Molecule Motion Map of GLIC by Diffracted X-Ray Tracking Biophysical Journal. 108: 191a-192a. DOI: 10.1016/J.BPJ.2014.11.1059  0.252
1971 Wahl P, Kasai M, Changeux J. A Study on the Motion Of Protenis in Excitable Membrane Fragment by Nanosecond Fluorescence Polarization Spectroscopy Febs Journal. 18: 332-341. PMID 5542943 DOI: 10.1111/J.1432-1033.1971.Tb01248.X  0.251
1995 Changeux JP. Thudichum Medal Lecture. The acetylcholine receptor: a model for allosteric membrane proteins. Biochemical Society Transactions. 23: 195-205. PMID 7545603  0.251
2017 Changeux JP. Climbing Brain Levels of Organisation from Genes to Consciousness. Trends in Cognitive Sciences. PMID 28161289 DOI: 10.1016/j.tics.2017.01.004  0.248
1990 Garcia L, Pinçon-Raymond M, Romey G, Changeux JP, Lazdunski M, Rieger F. Induction of normal ultrastructure by CGRP treatment in dysgenic myotubes. Febs Letters. 263: 147-52. PMID 2158902 DOI: 10.1016/0014-5793(90)80725-X  0.248
1970 Blumenthal R, Changeux JP, Lefever R. Membrane excitability and dissipative instabilities. The Journal of Membrane Biology. 2: 351-74. PMID 24174157 DOI: 10.1007/BF01869870  0.248
1974 Weber M, Changeux JP. Binding of Naja nigricollis [3H]α toxin to membrane fragments from Electrophorus and Torpedo electric organs. III. Effects of local anaesthetics on the binding of the tritiated α neurotoxin Molecular Pharmacology. 10: 35-40. PMID 4846183  0.246
2020 Cerdan AH, Sisquellas M, Pereira G, Barreto Gomes DE, Changeux JP, Cecchini M. The Glycine Receptor Allosteric Ligands Library (GRALL). Bioinformatics (Oxford, England). PMID 32163115 DOI: 10.1093/Bioinformatics/Btaa170  0.242
2005 Gisiger T, Kerszberg M, Changeux JP. Acquisition and performance of delayed-response tasks: a neural network model. Cerebral Cortex (New York, N.Y. : 1991). 15: 489-506. PMID 15342439 DOI: 10.1093/cercor/bhh149  0.24
1971 Patrick J, Valeur B, Monnerie L, Changeux JP. Changes in extrinsic fluorescence intensity of the electroplax membrane during electrical excitation. The Journal of Membrane Biology. 5: 102-20. PMID 24172986 DOI: 10.1007/BF01870827  0.239
2014 Sasaki Y, Sekiguchi H, Matsushita Y, Ikezaki K, Nishino Y, Miyazawa A, Huon C, Changeux J, Corringer P. 1P218 PH dependent 3D Motion Maps of GLIC from X-ray Single Molecule Observations(13C. Biological & Artificial membrane: Excitation & Channels,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014)) Seibutsu Butsuri. 54: S177. DOI: 10.2142/biophys.54.S177_2  0.239
2023 Shi S, Lefebvre SN, Peverini L, Cerdan AH, Milán Rodríguez P, Gielen M, Changeux JP, Cecchini M, Corringer PJ. Illumination of a progressive allosteric mechanism mediating the glycine receptor activation. Nature Communications. 14: 795. PMID 36781912 DOI: 10.1038/s41467-023-36471-7  0.239
1969 Podleski T, Changeux JP. Effects associated with permeability changes caused by Gramicidin A in electroplax membrane Nature. 221: 541-545. PMID 5789298 DOI: 10.1038/221541a0  0.238
2013 Rømer Thomsen K, Joensson M, Lou HC, Møller A, Gross J, Kringelbach ML, Changeux JP. Altered paralimbic interaction in behavioral addiction. Proceedings of the National Academy of Sciences of the United States of America. 110: 4744-9. PMID 23487797 DOI: 10.1073/Pnas.1302374110  0.237
1989 Villar MJ, Roa M, Huchet M, Hökfelt T, Changeux JP, Fahrenkrug J, Brown JC, Epstein M, Hersh L. Immunoreactive Calcitonin Gene-Related Peptide, Vasoactive Intestinal Polypeptide, and Somatostatin in Developing Chicken Spinal Cord Motoneurons. The European Journal of Neuroscience. 1: 269-287. PMID 12106158 DOI: 10.1111/J.1460-9568.1989.Tb00795.X  0.237
2017 Evers K, Changeux JP. Response by the authors. Embo Reports. PMID 28743712 DOI: 10.15252/embr.201744696  0.236
1984 Giraudat J, Devillers-Thiery A, Perriard J, Changeux J. Complete nucleotide sequence of Torpedo marmorata mRNA coding for the 43,000-dalton nu 2 protein: muscle-specific creatine kinase. Proceedings of the National Academy of Sciences of the United States of America. 81: 7313-7317. PMID 6095285 DOI: 10.1073/Pnas.81.23.7313  0.236
2006 Grailhe R, Merola F, Ridard J, Couvignou S, Le Poupon C, Changeux JP, Laguitton-Pasquier H. Monitoring protein interactions in the living cell through the fluorescence decays of the cyan fluorescent protein. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 7: 1442-54. PMID 16739159 DOI: 10.1002/cphc.200600057  0.235
1983 Tzartos SJ, Changeux JP. High affinity binding of alpha-bungarotoxin to the purified alpha-subunit and to its 27,000-dalton proteolytic peptide from Torpedo marmorata acetylcholine receptor. Requirement for sodium dodecyl sulfate Embo Journal. 2: 381-387. PMID 11894953  0.234
1967 Changeux JP, Thiéry J, Tung Y, Kittel C. On the cooperativity of biological membranes. Proceedings of the National Academy of Sciences of the United States of America. 57: 335-41. PMID 16591474 DOI: 10.1073/Pnas.57.2.335  0.233
2012 Granon S, Changeux JP. Deciding between conflicting motivations: what mice make of their prefrontal cortex. Behavioural Brain Research. 229: 419-26. PMID 22108342 DOI: 10.1016/j.bbr.2011.11.011  0.233
2021 Goulas A, Changeux JP, Wagstyl K, Amunts K, Palomero-Gallagher N, Hilgetag CC. The natural axis of transmitter receptor distribution in the human cerebral cortex. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33452137 DOI: 10.1073/pnas.2020574118  0.233
1980 Toutant M, Bourgeois J, Toutant J, Renaud D, Douarin GL, Changeux J. Chronic stimulation of the spinal cord in developing chick embryo causes the differentiation of multiple clusters of acetylcholine receptor in the posterior latissimus dorsi muscle Developmental Biology. 76: 384-395. PMID 7390009 DOI: 10.1016/0012-1606(80)90387-5  0.232
1994 Kerszberg M, Changeux JP. A model for reading morphogenetic gradients: autocatalysis and competition at the gene level. Proceedings of the National Academy of Sciences of the United States of America. 91: 5823-7. PMID 8016073 DOI: 10.1073/pnas.91.13.5823  0.232
2016 Changeux J. El hombre neuronal, treinta años después Ciencias Sociales Y EducacióN. 5: 201-219. DOI: 10.22395/CSYE.V5N10A9  0.232
1998 Lu Y, Grady S, Marks MJ, Picciotto M, Changeux JP, Collins AC. Pharmacological characterization of nicotinic receptor-stimulated GABA release from mouse brain synaptosomes. The Journal of Pharmacology and Experimental Therapeutics. 287: 648-57. PMID 9808692  0.23
1983 Gouzé JL, Lasry JM, Changeux JP. Selective stabilization of muscle innervation during development: a mathematical model. Biological Cybernetics. 46: 207-15. PMID 6850005 DOI: 10.1007/BF00336802  0.226
1974 Weber M, Changeux JP. Binding of Naja nigricollis [3H]α toxin to membrane fragments from Electrophorus and Torpedo electric organs. II. Effect of cholinergic agonists and antagonists on the binding of the tritiated α neurotoxin Molecular Pharmacology. 10: 15-34. PMID 4846182  0.225
1975 Giacobini-Robecchi MG, Giacobini G, Filogamo G, Changeux J. Effects of the type A toxin fromClostridium botulinum on the development of skeletal muscles and of their innervation in chick embryo Brain Research. 83: 107-121. DOI: 10.1016/0006-8993(75)90862-8  0.224
2022 Cerdan AH, Peverini L, Changeux JP, Corringer PJ, Cecchini M. Lateral fenestrations in the extracellular domain of the glycine receptor contribute to the main chloride permeation pathway. Science Advances. 8: eadc9340. PMID 36240268 DOI: 10.1126/sciadv.adc9340  0.224
2019 Changeux J. Two Cultures and Our Encyclopaedic Brain European Review. 27: 54-65. DOI: 10.1017/S1062798718000534  0.222
2009 Lagercrantz H, Changeux JP. The emergence of human consciousness: from fetal to neonatal life. Pediatric Research. 65: 255-60. PMID 19092726 DOI: 10.1203/Pdr.0B013E3181973B0D  0.22
2006 Vincent P, Maskos U, Charvet I, Bourgeais L, Stoppini L, Leresche N, Changeux JP, Lambert R, Meda P, Paupardin-Tritsch D. Live imaging of neural structure and function by fibred fluorescence microscopy. Embo Reports. 7: 1154-61. PMID 17008931 DOI: 10.1038/Sj.Embor.7400801  0.22
1973 Menez A, Bouet F, Morgat J, Ronsseray A, Boquet P, Changeux J, Fromageot P. Studies of tubocurarine labelled with iodine or tritium. Biochimie. 55: 919-924. PMID 4772294 DOI: 10.1016/S0300-9084(73)80169-5  0.218
2012 Changeux JP. Conscious processing: implications for general anesthesia. Current Opinion in Anaesthesiology. 25: 397-404. PMID 22699320 DOI: 10.1097/ACO.0b013e32835561de  0.218
1993 Hill JA, Zoli M, Bourgeois JP, Changeux JP. Immunocytochemical localization of a neuronal nicotinic receptor: the beta 2-subunit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 1551-68. PMID 8463835  0.217
1994 Mendelzon D, Changeux JP, Nghiêm HO. Phosphorylation of myogenin in chick myotubes: regulation by electrical activity and by protein kinase C. Implications for acetylcholine receptor gene expression. Biochemistry. 33: 2568-75. PMID 8117718  0.217
1991 Villar MJ, Roa M, Huchet M, Changeux JP, Valentino KL, Hökfelt T. Occurrence of neuropeptide K-like immunoreactivity in ventral horn cells of the chicken spinal cord during development Brain Research. 541: 149-153. PMID 2029616 DOI: 10.1016/0006-8993(91)91089-J  0.216
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