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Anthony R. Braun, Ph.D. - Publications

Affiliations: 
2014 Biomedical Engineering University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Biomedical Engineering, General Biophysics, Neuroscience Biology
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44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kochen NN, Seaney D, Vasandani V, Murray M, Braun AR, Sachs JN. Post-translational modification sites are present in hydrophilic cavities of alpha-synuclein, tau, FUS, and TDP-43 fibrils: A molecular dynamics study. Proteins. PMID 38458997 DOI: 10.1002/prot.26679  0.569
2023 Liao EE, Yang M, Nathan Kochen N, Vunnam N, Braun AR, Ferguson DM, Sachs JN. Proteasomal Stimulation by MK886 and Its Derivatives Can Rescue Tau-Induced Neurite Pathology. Molecular Neurobiology. PMID 37428404 DOI: 10.1007/s12035-023-03417-5  0.64
2023 Braun AR, Kochen NN, Yuen SL, Liao EE, Cornea RL, Thomas DD, Sachs JN. Advancements in a FRET Biosensor for Live-Cell Fluorescence-Lifetime High-Throughput Screening of Alpha-Synuclein. Asn Neuro. 15: 17590914231184086. PMID 37428128 DOI: 10.1177/17590914231184086  0.556
2023 Pandey AK, Buchholz CR, Nathan Kochen N, Pomerantz WCK, Braun AR, Sachs JN. pH Effects Can Dominate Chemical Shift Perturbations in H,N-HSQC NMR Spectroscopy for Studies of Small Molecule/α-Synuclein Interactions. Acs Chemical Neuroscience. PMID 36749138 DOI: 10.1021/acschemneuro.2c00782  0.546
2022 Ratnapriya S, Braun AR, Cervera Benet H, Carlson D, Ding S, Paulson CN, Mishra N, Sachs JN, Aldrich CC, Finzi A, Herschhorn A. Broad Tricyclic Ring Inhibitors Block SARS-CoV-2 Spike Function Required for Viral Entry. Acs Infectious Diseases. PMID 36153947 DOI: 10.1021/acsinfecdis.1c00658  0.562
2022 Nathan Kochen N, Vasandani V, Seaney D, Pandey AK, Walters MA, Braun AR, Sachs JN. Threonine Cavities Are Targetable Motifs That Control Alpha-Synuclein Fibril Growth. Acs Chemical Neuroscience. PMID 36001084 DOI: 10.1021/acschemneuro.2c00327  0.583
2021 Braun AR, Liao EE, Horvath M, Kalra P, Acosta K, Young MC, Kochen NN, Lo CH, Brown R, Evans MD, Pomerantz WCK, Rhoades E, Luk K, Cornea RL, Thomas DD, et al. Potent inhibitors of toxic alpha-synuclein identified via cellular time-resolved FRET biosensors. Npj Parkinson's Disease. 7: 52. PMID 34183676 DOI: 10.1038/s41531-021-00195-6  0.686
2019 Lo CH, Lim CK, Ding Z, Wickramasinghe SP, Braun AR, Ashe KH, Rhoades E, Thomas DD, Sachs JN. Targeting the ensemble of heterogeneous tau oligomers in cells: A novel small molecule screening platform for tauopathies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31653529 DOI: 10.1016/J.Jalz.2019.06.4954  0.581
2018 Braun AR, Lacy MM, Ducas VC, Chen Z, Baumgart T, Rhoades E, Sachs JN. Correction to: α-Synuclein's Uniquely Long Amphipathic Helix Enhances its Membrane Binding and Remodeling Capacity. The Journal of Membrane Biology. PMID 30054671 DOI: 10.1007/S00232-018-0042-Y  0.606
2018 Young M, Braun AR, Sachs JN, Hung Lo C. Developing Novel FRET Based Biosensors that Monitor α-Synuclein Assembly for Use in High Throughput Screening Biophysical Journal. 114: 77a. DOI: 10.1016/J.Bpj.2017.11.465  0.572
2018 Beaven AH, Romo TD, Lewis AK, Braun AR, Grossfield A, Sachs JN. Computational Studies of Alpha-Synuclein Fibril Formation and Stability Biophysical Journal. 114: 230a. DOI: 10.1016/J.Bpj.2017.11.1278  0.697
2017 Romo TD, Lewis AK, Braun AR, Grossfield A, Sachs JN. Minimal nucleation state of alpha-Synuclein is stabilized by dynamic threonine-water networks. Acs Chemical Neuroscience. PMID 28677385 DOI: 10.1021/Acschemneuro.7B00171  0.729
2017 Braun AR, Lacy MM, Ducas VC, Rhoades E, Sachs JN. α-Synuclein's Uniquely Long Amphipathic Helix Enhances its Membrane Binding and Remodeling Capacity. The Journal of Membrane Biology. PMID 28239748 DOI: 10.1007/S00232-017-9946-1  0.68
2016 Brummel BE, Braun AR, Sachs JN. Polyunsaturated chains in asymmetric lipids disorder raft mixtures and preferentially associate with α-Synuclein. Biochimica Et Biophysica Acta. PMID 27742354 DOI: 10.1016/J.Bbamem.2016.10.006  0.653
2016 Lewis AK, Valley CC, Peery SL, Brummel B, Braun AR, Karim C, Sachs JN. Death Receptor 5 Networks Require Membrane Cholesterol for Proper Structure and Function. Journal of Molecular Biology. PMID 27720987 DOI: 10.1016/J.Jmb.2016.10.001  0.789
2016 West A, Brummel BE, Braun AR, Rhoades E, Sachs JN. Membrane remodeling and mechanics: Experiments and simulations of α-Synuclein. Biochimica Et Biophysica Acta. PMID 26972046 DOI: 10.1016/J.Bbamem.2016.03.012  0.671
2015 Braun AR, Sachs JN. α-Synuclein Reduces Tension and Increases Undulations in Simulations of Small Unilamellar Vesicles. Biophysical Journal. 108: 1848-51. PMID 25902424 DOI: 10.1016/J.Bpj.2015.03.029  0.663
2015 Braun AR, Sachs JN. Alpha-Synuclein Stabilizes Small Unilamellar Vesicles by Reducing Both Membrane Surface Tension and Rigidity Biophysical Journal. 108: 547a. DOI: 10.1016/J.Bpj.2014.11.3001  0.672
2014 Braun AR, Sachs JN. Determining Structural and Mechanical Properties from Molecular Dynamics Simulations of Lipid Vesicles. Journal of Chemical Theory and Computation. 10: 4160-4168. PMID 25221448 DOI: 10.1021/Ct500460U  0.659
2014 Braun AR, Lacy MM, Ducas VC, Rhoades E, Sachs JN. α-Synuclein-induced membrane remodeling is driven by binding affinity, partition depth, and interleaflet order asymmetry. Journal of the American Chemical Society. 136: 9962-72. PMID 24960410 DOI: 10.1021/Ja5016958  0.683
2014 Lewis AK, James ZM, McCaffrey JE, Braun AR, Karim CB, Thomas DD, Sachs JN. Open and closed conformations of the isolated transmembrane domain of death receptor 5 support a new model of activation. Biophysical Journal. 106: L21-4. PMID 24655519 DOI: 10.1016/J.Bpj.2014.01.044  0.736
2014 Boscia AL, Treece BW, Mohammadyani D, Klein-Seetharaman J, Braun AR, Wassenaar TA, Klösgen B, Tristram-Nagle S. X-ray structure, thermodynamics, elastic properties and MD simulations of cardiolipin/dimyristoylphosphatidylcholine mixed membranes. Chemistry and Physics of Lipids. 178: 1-10. PMID 24378240 DOI: 10.1016/J.Chemphyslip.2013.12.010  0.423
2014 Lewis AK, Valley CC, Braun AR, Sachs JN. Quantitative Analysis of Ligand-Induced Supramolecular Clustering of Death Receptor 5 in Jurkat Cells Biophysical Journal. 106: 715a. DOI: 10.1016/J.Bpj.2013.11.3953  0.776
2014 Braun AR, Sachs JN. Extracting Structural and Mechanical Properties of Lipid Vesicles from Molecular Dynamics Simulations Biophysical Journal. 106: 710a. DOI: 10.1016/J.Bpj.2013.11.3915  0.676
2014 Lacy MM, Ducas VC, Braun AR, Sachs JN, Rhoades E. Assessing the Structural Dynamics and Membrane Interactions of the Disordered Protein Alpha-Synuclein Biophysical Journal. 106: 267a-268a. DOI: 10.1016/J.Bpj.2013.11.1568  0.681
2013 Braun AR, Sachs JN, Nagle JF. Comparing simulations of lipid bilayers to scattering data: the GROMOS 43A1-S3 force field. The Journal of Physical Chemistry. B. 117: 5065-72. PMID 23560979 DOI: 10.1021/Jp401718K  0.6
2013 Braun AR, Sachs JN. α-Synuclein Induced Membrane Curvature: What is the Significance of Negative Gaussian Curvature Biophysical Journal. 104: 95a. DOI: 10.1016/J.Bpj.2012.11.564  0.682
2012 Valley CC, Lewis AK, Mudaliar DJ, Perlmutter JD, Braun AR, Karim CB, Thomas DD, Brody JR, Sachs JN. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces death receptor 5 networks that are highly organized. The Journal of Biological Chemistry. 287: 21265-78. PMID 22496450 DOI: 10.1074/Jbc.M111.306480  0.747
2012 Braun AR, Sevcsik E, Chin P, Rhoades E, Tristram-Nagle S, Sachs JN. α-Synuclein induces both positive mean curvature and negative Gaussian curvature in membranes. Journal of the American Chemical Society. 134: 2613-20. PMID 22211521 DOI: 10.1021/Ja208316H  0.671
2012 Braun AR, Sevcsik E, Rhoades E, Tristram-Nagle S, Sachs JN. The Nature of Membrane Curvature-Induction by Amphipathic α-Helices Relies upon Protein Length: Simulations of α-Synuclein and H0 Biophysical Journal. 102: 237a. DOI: 10.1016/J.Bpj.2011.11.1301  0.677
2011 Valley CC, Perlmutter JD, Braun AR, Sachs JN. NaCl interactions with phosphatidylcholine bilayers do not alter membrane structure but induce long-range ordering of ions and water. The Journal of Membrane Biology. 244: 35-42. PMID 22015614 DOI: 10.1007/S00232-011-9395-1  0.768
2011 Braun AR, Brandt EG, Edholm O, Nagle JF, Sachs JN. Determination of electron density profiles and area from simulations of undulating membranes. Biophysical Journal. 100: 2112-20. PMID 21539778 DOI: 10.1016/J.Bpj.2011.03.009  0.624
2011 Brandt EG, Braun AR, Sachs JN, Nagle JF, Edholm O. Interpretation of fluctuation spectra in lipid bilayer simulations. Biophysical Journal. 100: 2104-11. PMID 21539777 DOI: 10.1016/J.Bpj.2011.03.010  0.603
2011 Brandt EG, Braun AR, Sachs JN, Nagle JF, Edholm O. Direct Fourier Analysis of Lipid Bilayer Fluctuations in Particle-Based Simulations Biophysical Journal. 100: 491a. DOI: 10.1016/J.Bpj.2010.12.2881  0.595
2011 Braun AR, Tristram-Nagle S, Sachs JN. Structure and Bending Rigidity of SOPC, SOPC-Cholesterol, and SOPC-LWYIK Bilayers: A Comparison of Molecular Dynamics and X-Ray Scattering Results Biophysical Journal. 100: 490a. DOI: 10.1016/J.Bpj.2010.12.2873  0.625
2011 Valley CC, Braun AR, Sachs JN. Pre-Ligand Assembly of TNF Receptors Through Covalent and Non-Covalent Interactions Biophysical Journal. 100: 419a-420a. DOI: 10.1016/J.Bpj.2010.12.2485  0.786
2011 Altun A, Bartlett RJ, Bergonzo C, Braun AR, Bylaska EJ, Daniel Crawford T, de Jong WA, Deumens E, Erik Nielsen J, Fortenberry RC, Govind N, Hayat S, Helms V, Jindal N, Johnston MA, et al. Contributors Annual Reports in Computational Chemistry. 7: ix-xi. DOI: 10.1016/B978-0-444-53835-2.00017-1  0.464
2011 Braun AR, Sachs JN. Extracting Experimental Measurables from Molecular Dynamics Simulations of Membranes Annual Reports in Computational Chemistry. 7: 125-150. DOI: 10.1016/B978-0-444-53835-2.00006-7  0.635
2010 Braun AR, Frink LJ, Sachs JN. Probing the Molecular Structure of Polymer DNA Nanoparticles Via Fluids-DFT Biophysical Journal. 98: 658a. DOI: 10.1016/J.Bpj.2009.12.3608  0.555
2010 Braun AR, Edholm O, Brandt EG, Nagle JF, Sachs JN. Characterization of Electron Density Profiles and Area Per Lipid from MD Simulation of Large Undulating Bilayers Biophysical Journal. 98: 569a. DOI: 10.1016/J.Bpj.2009.12.3087  0.619
2010 Sachs JN, Perlmutter JD, Braun AR, Sevcsik E, Tristram-Nagle S, Rhoades E. Probing the Membrane Deformations Induced by Binding of Membrane Proteins: Alpha-Synuclein and CRAC Biophysical Journal. 98: 487a-488a. DOI: 10.1016/J.Bpj.2009.12.2655  0.802
2009 Perlmutter JD, Braun AR, Sachs JN. Curvature dynamics of alpha-synuclein familial Parkinson disease mutants: molecular simulations of the micelle- and bilayer-bound forms. The Journal of Biological Chemistry. 284: 7177-89. PMID 19126542 DOI: 10.1074/Jbc.M808895200  0.79
2009 Perlmutter JD, Braun AR, Sachs JN. Curvature Dynamics of α-Synuclein Familial Parkinson's Disease Mutants: Molecular Dynamics Simulations of the Micelle- and Membrane-Bound Forms Biophysical Journal. 96: 340a. DOI: 10.1016/J.Bpj.2008.12.3830  0.802
2009 Braun AR. A Novel Analysis Technique For Determining Area Per Lipid And Electron Density Profiles From Large Lipid Bilayer Molecular Dynamics Simulations Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.111  0.362
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