| Year |
Citation |
Score |
| 2021 |
Poole LG, Fournier AK, Cline-Fedewa HM, Kopec AK, Luyendyk JP, Groeneveld DJ. Von Willebrand factor exerts hepatoprotective effects in acute but not chronic cholestatic liver injury in mice. Toxicology. 463: 152968. PMID 34619301 DOI: 10.1016/j.tox.2021.152968 |
0.441 |
|
| 2021 |
Poole LG, Kopec AK, Groeneveld D, Pant A, Baker K, Cline-Fedewa HM, Flick MJ, Luyendyk JP. Factor XIII cross-links fibrin(ogen) independent of fibrin polymerization in experimental acute liver injury. Blood. PMID 33569603 DOI: 10.1182/blood.2020007415 |
0.374 |
|
| 2020 |
LaBranche TP, Kopec AK, Mantena SR, Hollingshead BD, Harrington AW, Stewart ZS, Zhan Y, Hayes KD, Whiteley LO, Burdick AD, Davis JW. Zucker Lean Rats With Hepatic Steatosis Recapitulate Asymptomatic Metabolic Syndrome and Exhibit Greater Sensitivity to Drug-Induced Liver Injury Compared With Standard Nonclinical Sprague-Dawley Rat Model. Toxicologic Pathology. 192623320968716. PMID 33252024 DOI: 10.1177/0192623320968716 |
0.301 |
|
| 2020 |
Miszta A, Kopec AK, Pant A, Holle L, Byrnes JR, Lawrence DA, Hansen K, Flick MJ, Luyendyk JP, de Laat B, Wolberg AS. High fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice. Blood. PMID 32315384 DOI: 10.1182/Blood.2019004267 |
0.399 |
|
| 2019 |
Baker KS, Kopec AK, Pant A, Poole LG, Cline-Fedewa H, Ivkovich D, Olyaee M, Woolbright BL, Miszta A, Jaeschke H, Wolberg AS, Luyendyk JP. Direct Amplification of TF (Tissue Factor). Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119313215. PMID 31412737 DOI: 10.1161/Atvbaha.119.313215 |
0.375 |
|
| 2019 |
Groeneveld D, Pereyra D, Veldhuis Z, Adelmeijer J, Ottens P, Kopec AK, Starlinger P, Lisman T, Luyendyk JP. Intrahepatic fibrin(ogen) deposition drives liver regeneration after partial hepatectomy in mice and humans. Blood. PMID 30655274 DOI: 10.1182/Blood-2018-08-869057 |
0.477 |
|
| 2018 |
Poole LG, Pant A, Baker KS, Kopec AK, Cline-Fedewa HM, Iismaa SE, Flick MJ, Luyendyk JP. Chronic liver injury drives non-traditional intrahepatic fibrin(ogen) cross-linking via tissue transglutaminase. Journal of Thrombosis and Haemostasis : Jth. PMID 30415489 DOI: 10.1111/Jth.14330 |
0.443 |
|
| 2018 |
Bates MA, Akbari P, Gilley KN, Wagner JG, Li N, Kopec AK, Wierenga KA, Jackson-Humbles D, Brandenberger C, Holian A, Benninghoff AD, Harkema JR, Pestka JJ. Dietary Docosahexaenoic Acid Prevents Silica-Induced Development of Pulmonary Ectopic Germinal Centers and Glomerulonephritis in the Lupus-Prone NZBWF1 Mouse. Frontiers in Immunology. 9: 2002. PMID 30258439 DOI: 10.3389/Fimmu.2018.02002 |
0.375 |
|
| 2018 |
Pant A, Kopec AK, Luyendyk JP. Role of the blood coagulation cascade in hepatic fibrosis. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 29723040 DOI: 10.1152/Ajpgi.00402.2017 |
0.418 |
|
| 2018 |
Pant A, Kopeć AK, Baker KS, Cline-Fedewa H, Lawrence DA, Luyendyk JP. Plasminogen Activator Inhibitor-1 Reduces tPA-Dependent Fibrinolysis and Intrahepatic Hemorrhage in Experimental Acetaminophen Overdose. The American Journal of Pathology. PMID 29454747 DOI: 10.1016/J.Ajpath.2018.01.010 |
0.54 |
|
| 2018 |
Boucher AA, Rosenfeldt LA, Mureb D, Kopec AK, Luyendyk JP, Flick MJ, Palumbo JS. Inflammation and Tissue Damage Mediated By PAR-1 Expression Is Cell Type-Specific and Varies Depending on the Inflammatory Challenge Blood. 132: 133-133. DOI: 10.1182/Blood-2018-99-117312 |
0.49 |
|
| 2017 |
Kopec AK, Spada AP, Contreras PC, Mackman N, Luyendyk JP. Caspase inhibition reduces hepatic tissue factor-driven coagulation in vitro and in vivo. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 29228388 DOI: 10.1093/Toxsci/Kfx268 |
0.497 |
|
| 2017 |
Kopec AK, Abrahams SR, Thornton S, Palumbo JS, Mullins ES, Divanovic S, Weiler H, Owens AP, Mackman N, Goss A, van Ryn J, Luyendyk JP, Flick MJ. Thrombin promotes diet-induced obesity through fibrin-driven inflammation. The Journal of Clinical Investigation. PMID 28737512 DOI: 10.1172/Jci92744 |
0.412 |
|
| 2017 |
Joshi N, Kopec AK, Ray JL, Cline-Fedewa H, Groeneveld DJ, Lisman T, Luyendyk JP. Von Willebrand factor deficiency reduces liver fibrosis in mice. Toxicology and Applied Pharmacology. PMID 28527913 DOI: 10.1016/J.Taap.2017.05.018 |
0.562 |
|
| 2017 |
Ray JL, Kopec AK, Joshi N, Cline-Fedewa H, Lash LH, Williams KJ, Leung PS, Eric Gerswhin M, Luyendyk JP. Trichloroethylene exposure reduces liver injury in a mouse model of primary biliary cholangitis. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28115651 DOI: 10.1093/Toxsci/Kfw264 |
0.591 |
|
| 2016 |
Joshi N, Kopec AK, Cline-Fedewa H, Luyendyk JP. Lymphocytes contribute to biliary injury and fibrosis in experimental xenobiotic-induced cholestasis. Toxicology. PMID 28049044 DOI: 10.1016/J.Tox.2016.12.009 |
0.542 |
|
| 2016 |
Kopec AK, Joshi N, Cline-Fedewa H, Wojcicki AV, Ray JL, Sullivan BP, Froehlich JE, Johnson BF, Flick MJ, Luyendyk JP. Fibri(nogen) drives repair after acetaminophen-induced liver injury via leukocyte αMβ2 integrin-dependent upregulation of MMP12. Journal of Hepatology. PMID 27965156 DOI: 10.1016/J.Jhep.2016.12.004 |
0.543 |
|
| 2016 |
Nault R, Fader KA, Kopec AK, Harkema JR, Zacharewski TR, Luyendyk JP. Coagulation-driven hepatic fibrosis requires protease activated receptor-1 (PAR-1) in a mouse model of TCDD-elicited steatohepatitis. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27613713 DOI: 10.1093/Toxsci/Kfw175 |
0.754 |
|
| 2016 |
Joshi N, Ray JL, Kopec AK, Luyendyk JP. Dose-dependent effects of alpha-naphthylisothiocyanate disconnect biliary fibrosis from hepatocellular necrosis. Journal of Biochemical and Molecular Toxicology. PMID 27605088 DOI: 10.1002/Jbt.21834 |
0.566 |
|
| 2016 |
Joshi N, Kopec AK, Ray JL, Luyendyk JP. Inhibition of PAR-4 and P2Y12 receptor-mediated platelet activation produces distinct hepatic pathologies in experimental xenobiotic-induced cholestatic liver disease. Toxicology. PMID 27475285 DOI: 10.1016/J.Tox.2016.07.021 |
0.502 |
|
| 2016 |
Kopec AK, Luyendyk JP. Role of Fibrin(ogen) in Progression of Liver Disease: Guilt by Association? Seminars in Thrombosis and Hemostasis. PMID 27144445 DOI: 10.1055/S-0036-1579655 |
0.438 |
|
| 2016 |
Kopec AK, Joshi N, Luyendyk JP. Role of hemostatic factors in hepatic injury and disease: Animal models de-liver. Journal of Thrombosis and Haemostasis : Jth. PMID 27060337 DOI: 10.1111/Jth.13327 |
0.436 |
|
| 2016 |
Joshi N, Kopec AK, Ray JL, Cline-Fedewa H, Nawabi A, Schmitt T, Nault R, Zacharewski TR, Rockwell CE, Flick MJ, Luyendyk JP. Fibrin deposition following bile duct injury limits fibrosis through an αMβ2-dependent mechanism. Blood. PMID 26921287 DOI: 10.1182/Blood-2015-09-670703 |
0.793 |
|
| 2015 |
Saini Y, Proper SP, Dornbos P, Greenwood KK, Kopec AK, Lynn SG, Grier E, Burgoon LD, Zacharewski TR, Thomas RS, Harkema JR, LaPres JJ. Loss of Hif-2α Rescues the Hif-1α Deletion Phenotype of Neonatal Respiratory Distress In Mice. Plos One. 10: e0139270. PMID 26422241 DOI: 10.1371/Journal.Pone.0139270 |
0.672 |
|
| 2015 |
Rautou PE, Tatsumi K, Antoniak S, Owens AP, Sparkenbaugh E, Holle LA, Wolberg AS, Kopec AK, Pawlinski R, Luyendyk JP, Mackman N. Hepatocyte tissue factor contributes to the hypercoagulable state in a mouse model of chronic liver injury. Journal of Hepatology. PMID 26325534 DOI: 10.1016/J.Jhep.2015.08.017 |
0.415 |
|
| 2015 |
Joshi N, Kopec AK, O'Brien KM, Towery KL, Cline-Fedewa H, Williams KJ, Copple BL, Flick MJ, Luyendyk JP. Coagulation-driven platelet activation reduces cholestatic liver injury and fibrosis in mice. Journal of Thrombosis and Haemostasis : Jth. 13: 57-71. PMID 25353084 DOI: 10.1111/Jth.12770 |
0.448 |
|
| 2014 |
Kopec AK, Joshi N, Towery KL, Kassel KM, Sullivan BP, Flick MJ, Luyendyk JP. Thrombin inhibition with dabigatran protects against high-fat diet-induced fatty liver disease in mice. The Journal of Pharmacology and Experimental Therapeutics. 351: 288-97. PMID 25138021 DOI: 10.1124/Jpet.114.218545 |
0.544 |
|
| 2014 |
Kopec AK, Sullivan BP, Kassel KM, Joshi N, Luyendyk JP. Toxicogenomic analysis reveals profibrogenic effects of trichloroethylene in autoimmune-mediated cholangitis in mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 141: 515-23. PMID 25055964 DOI: 10.1093/Toxsci/Kfu148 |
0.602 |
|
| 2014 |
Lopez M, Kopec AK, Joshi N, Geddings JE, Cline H, Towery KL, Rockwell CE, Mackman N, Luyendyk JP. Fas-induced apoptosis increases hepatocyte tissue factor procoagulant activity in vitro and in vivo. Toxicological Sciences : An Official Journal of the Society of Toxicology. 141: 453-64. PMID 25015658 DOI: 10.1093/Toxsci/Kfu139 |
0.421 |
|
| 2014 |
Kopec AK, Luyendyk JP. Coagulation in liver toxicity and disease: role of hepatocyte tissue factor. Thrombosis Research. 133: S57-9. PMID 24759146 DOI: 10.1016/J.Thromres.2014.03.023 |
0.465 |
|
| 2014 |
Joshi N, Kopec AK, Towery K, Williams KJ, Luyendyk JP. The antifibrinolytic drug tranexamic acid reduces liver injury and fibrosis in a mouse model of chronic bile duct injury. The Journal of Pharmacology and Experimental Therapeutics. 349: 383-92. PMID 24633426 DOI: 10.1124/Jpet.113.210880 |
0.542 |
|
| 2013 |
Kopec AK, Boverhof DR, Nault R, Harkema JR, Tashiro C, Potter D, Sharratt B, Chittim B, Zacharewski TR. Toxicogenomic evaluation of long-term hepatic effects of TCDD in immature, ovariectomized C57BL/6 mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 135: 465-75. PMID 23864506 DOI: 10.1093/Toxsci/Kft156 |
0.783 |
|
| 2013 |
Sullivan BP, Kopec AK, Joshi N, Cline H, Brown JA, Bishop SC, Kassel KM, Rockwell C, Mackman N, Luyendyk JP. Hepatocyte tissue factor activates the coagulation cascade in mice. Blood. 121: 1868-74. PMID 23305736 DOI: 10.1182/Blood-2012-09-455436 |
0.485 |
|
| 2012 |
Kopec AK, Thompson CM, Kim S, Forgacs AL, Zacharewski TR. Comparative toxicogenomic analysis of oral Cr(VI) exposure effects in rat and mouse small intestinal epithelia. Toxicology and Applied Pharmacology. 262: 124-38. PMID 22561333 DOI: 10.1016/J.Taap.2012.04.026 |
0.763 |
|
| 2012 |
Kopec AK, Kim S, Forgacs AL, Zacharewski TR, Proctor DM, Harris MA, Haws LC, Thompson CM. Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90days of exposure to hexavalent chromium in drinking water. Toxicology and Applied Pharmacology. 259: 13-26. PMID 22155349 DOI: 10.1016/J.Taap.2011.11.012 |
0.766 |
|
| 2011 |
Kopec AK, D'Souza ML, Mets BD, Burgoon LD, Reese SE, Archer KJ, Potter D, Tashiro C, Sharratt B, Harkema JR, Zacharewski TR. Non-additive hepatic gene expression elicited by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153) co-treatment in C57BL/6 mice. Toxicology and Applied Pharmacology. 256: 154-67. PMID 21851831 DOI: 10.1016/J.Taap.2011.08.002 |
0.787 |
|
| 2011 |
Thompson CM, Proctor DM, Haws LC, Hébert CD, Grimes SD, Shertzer HG, Kopec AK, Hixon JG, Zacharewski TR, Harris MA. Investigation of the mode of action underlying the tumorigenic response induced in B6C3F1 mice exposed orally to hexavalent chromium. Toxicological Sciences : An Official Journal of the Society of Toxicology. 123: 58-70. PMID 21712504 DOI: 10.1093/Toxsci/Kfr164 |
0.653 |
|
| 2010 |
Kopec AK, Burgoon LD, Ibrahim-Aibo D, Burg AR, Lee AW, Tashiro C, Potter D, Sharratt B, Harkema JR, Rowlands JC, Budinsky RA, Zacharewski TR. Automated dose-response analysis and comparative toxicogenomic evaluation of the hepatic effects elicited by TCDD, TCDF, and PCB126 in C57BL/6 mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 118: 286-97. PMID 20702594 DOI: 10.1093/Toxsci/Kfq236 |
0.786 |
|
| 2010 |
Kopec AK, Burgoon LD, Ibrahim-Aibo D, Mets BD, Tashiro C, Potter D, Sharratt B, Harkema JR, Zacharewski TR. PCB153-elicited hepatic responses in the immature, ovariectomized C57BL/6 mice: comparative toxicogenomic effects of dioxin and non-dioxin-like ligands. Toxicology and Applied Pharmacology. 243: 359-71. PMID 20005886 DOI: 10.1016/J.Taap.2009.12.003 |
0.785 |
|
| 2008 |
Kopec AK, Boverhof DR, Burgoon LD, Ibrahim-Aibo D, Harkema JR, Tashiro C, Chittim B, Zacharewski TR. Comparative toxicogenomic examination of the hepatic effects of PCB126 and TCDD in immature, ovariectomized C57BL/6 mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 102: 61-75. PMID 18042819 DOI: 10.1093/Toxsci/Kfm289 |
0.798 |
|
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