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Mary A. Dwyer, Ph.D. - Publications

Affiliations: 
2004 Duke University, Durham, NC 
Area:
Biochemistry
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Chen S, Ryan DA, Dwyer MA, Cashman JR. Synergistic effect of Wnt modulatory small molecules and an osteoinductive ceramic on C2C12 cell osteogenic differentiation. Bone. 67: 109-21. PMID 24998670 DOI: 10.1016/j.bone.2014.06.032  0.92
2013 Hu P, Herrmann R, Bednar A, Saloupis P, Dwyer MA, Yang P, Qi X, Thomas RS, Jaffe GJ, Boulton ME, McDonnell DP, Malek G. Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology. Proceedings of the National Academy of Sciences of the United States of America. 110: E4069-78. PMID 24106308 DOI: 10.1073/pnas.1307574110  0.92
2012 Motika MS, Zhang J, Ralph EC, Dwyer MA, Cashman JR. pH dependence on functional activity of human and mouse flavin-containing monooxygenase 5. Biochemical Pharmacology. 83: 962-8. PMID 22266355 DOI: 10.1016/j.bcp.2012.01.006  0.92
2012 Malek G, Dwyer M, McDonnell D. Exploring the potential role of the oxidant-activated transcription factor aryl hydrocarbon receptor in the pathogenesis of AMD Advances in Experimental Medicine and Biology. 723: 51-59. PMID 22183315 DOI: 10.1007/978-1-4614-0631-0_8  0.92
2011 Michalek RD, Gerriets VA, Nichols AG, Inoue M, Kazmin D, Chang CY, Dwyer MA, Nelson ER, Pollizzi KN, Ilkayeva O, Giguere V, Zuercher WJ, Powell JD, Shinohara ML, McDonnell DP, et al. Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation. Proceedings of the National Academy of Sciences of the United States of America. 108: 18348-53. PMID 22042850 DOI: 10.1073/pnas.1108856108  0.92
2011 Dwyer MA, Kazmin D, Hu P, McDonnell DP, Malek G. Research resource: nuclear receptor atlas of human retinal pigment epithelial cells: potential relevance to age-related macular degeneration. Molecular Endocrinology (Baltimore, Md.). 25: 360-72. PMID 21239617 DOI: 10.1210/me.2010-0392  0.92
2010 Dwyer MA, Joseph JD, Wade HE, Eaton ML, Kunder RS, Kazmin D, Chang CY, McDonnell DP. WNT11 expression is induced by estrogen-related receptor alpha and beta-catenin and acts in an autocrine manner to increase cancer cell migration. Cancer Research. 70: 9298-308. PMID 20870744 DOI: 10.1158/0008-5472.CAN-10-0226  0.92
2009 Joseph JD, Wittmann BM, Dwyer MA, Cui H, Dye DA, McDonnell DP, Norris JD. Inhibition of prostate cancer cell growth by second-site androgen receptor antagonists. Proceedings of the National Academy of Sciences of the United States of America. 106: 12178-83. PMID 19574450 DOI: 10.1073/pnas.0900185106  0.92
2009 Grasfeder LL, Gaillard S, Hammes SR, Ilkayeva O, Newgard CB, Hochberg RB, Dwyer MA, Chang CY, McDonnell DP. Fasting-induced hepatic production of DHEA is regulated by PGC-1alpha, ERRalpha, and HNF4alpha. Molecular Endocrinology (Baltimore, Md.). 23: 1171-82. PMID 19389810 DOI: 10.1210/me.2009-0024  0.92
2008 Dwyer MA, Looger LL, Hellinga HW. Retraction. Science (New York, N.Y.). 319: 569. PMID 18239106 DOI: 10.1126/science.319.5863.569b  0.92
2007 Mettu NB, Stanley TB, Dwyer MA, Jansen MS, Allen JE, Hall JM, McDonnell DP. The nuclear receptor-coactivator interaction surface as a target for peptide antagonists of the peroxisome proliferator-activated receptors. Molecular Endocrinology (Baltimore, Md.). 21: 2361-77. PMID 17595321 DOI: 10.1210/me.2007-0201  0.92
2007 Allert M, Dwyer MA, Hellinga HW. Local encoding of computationally designed enzyme activity. Journal of Molecular Biology. 366: 945-53. PMID 17196220 DOI: 10.1016/j.jmb.2006.12.002  0.92
2007 Gaillard S, Dwyer MA, McDonnell DP. Definition of the molecular basis for estrogen receptor-related receptor-alpha-cofactor interactions. Molecular Endocrinology (Baltimore, Md.). 21: 62-76. PMID 17053040 DOI: 10.1210/me.2006-0179  0.92
2004 Dwyer MA, Hellinga HW. Periplasmic binding proteins: a versatile superfamily for protein engineering. Current Opinion in Structural Biology. 14: 495-504. PMID 15313245 DOI: 10.1016/j.sbi.2004.07.004  0.92
2004 Dwyer MA, Looger LL, Hellinga HW. Computational design of a biologically active enzyme. Science (New York, N.Y.). 304: 1967-71. PMID 15218149 DOI: 10.1126/science.1098432  0.92
2004 Bernat B, Sun M, Dwyer M, Feldkamp M, Kossiakoff AA. Dissecting the binding energy epitope of a high-affinity variant of human growth hormone: cooperative and additive effects from combining mutations from independently selected phage display mutagenesis libraries. Biochemistry. 43: 6076-84. PMID 15147191 DOI: 10.1021/bi036069b  0.92
2003 Dwyer MA, Looger LL, Hellinga HW. Computational design of a Zn2+ receptor that controls bacterial gene expression. Proceedings of the National Academy of Sciences of the United States of America. 100: 11255-60. PMID 14500902 DOI: 10.1073/pnas.2032284100  0.92
2003 Looger LL, Dwyer MA, Smith JJ, Hellinga HW. Computational design of receptor and sensor proteins with novel functions. Nature. 423: 185-90. PMID 12736688 DOI: 10.1038/nature01556  0.92
2002 de Lorimier RM, Smith JJ, Dwyer MA, Looger LL, Sali KM, Paavola CD, Rizk SS, Sadigov S, Conrad DW, Loew L, Hellinga HW. Construction of a fluorescent biosensor family. Protein Science : a Publication of the Protein Society. 11: 2655-75. PMID 12381848 DOI: 10.1110/ps.021860  0.92
2002 Rajagopalan PT, Zhang Z, McCourt L, Dwyer M, Benkovic SJ, Hammes GG. Interaction of dihydrofolate reductase with methotrexate: ensemble and single-molecule kinetics. Proceedings of the National Academy of Sciences of the United States of America. 99: 13481-6. PMID 12359872 DOI: 10.1073/pnas.172501499  0.92
2001 Dwyer JJ, Dwyer MA, Kossiakoff AA. High affinity RNase S-peptide variants obtained by phage display have a novel "hot-spot" of binding energy. Biochemistry. 40: 13491-500. PMID 11695896 DOI: 10.1021/bi011703b  0.92
2001 Roberge M, Santell L, Dennis MS, Eigenbrot C, Dwyer MA, Lazarus RA. A novel exosite on coagulation factor VIIa and its molecular interactions with a new class of peptide inhibitors. Biochemistry. 40: 9522-31. PMID 11583151 DOI: 10.1021/bi010592d  0.92
2000 Dwyer MA, Lu W, Dwyer JJ, Kossiakoff AA. Biosynthetic phage display: a novel protein engineering tool combining chemical and genetic diversity. Chemistry & Biology. 7: 263-74. PMID 10780926 DOI: 10.1016/S1074-5521(00)00102-2  0.92
2000 Dennis MS, Eigenbrot C, Skelton NJ, Ultsch MH, Santell L, Dwyer MA, O'Connell MP, Lazarus RA. Peptide exosite inhibitors of factor VIIa as anticoagulants. Nature. 404: 465-70. PMID 10761907 DOI: 10.1038/35006574  0.92
1999 Dwyer MA, Huang AJ, Pan CQ, Lazarus RA. Expression and characterization of a DNase I-Fc fusion enzyme. The Journal of Biological Chemistry. 274: 9738-43. PMID 10092662 DOI: 10.1074/jbc.274.14.9738  0.92
1991 Dwyer MA, Bredt DS, Snyder SH. Nitric oxide synthase: irreversible inhibition by L-NG-nitroarginine in brain in vitro and in vivo. Biochemical and Biophysical Research Communications. 176: 1136-41. PMID 1710109 DOI: 10.1016/0006-291X(91)90403-T  0.92
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