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Kathleen M. Holtz, Ph.D. - Publications

Affiliations: 
2000 Boston College, Newton, MA, United States 
Area:
Biochemistry
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7 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2005 Stec B, Holtz KM, Wojciechowski CL, Kantrowitz ER. Structure of the wild-type TEM-1 beta-lactamase at 1.55 A and the mutant enzyme Ser70Ala at 2.1 A suggest the mode of noncovalent catalysis for the mutant enzyme. Acta Crystallographica. Section D, Biological Crystallography. 61: 1072-9. PMID 16041072 DOI: 10.1107/S0907444905014356  0.466
2000 Holtz KM, Catrina IE, Hengge AC, Kantrowitz ER. Mutation of Arg-166 of alkaline phosphatase alters the thio effect but not the transition state for phosphoryl transfer. Implications for the interpretation of thio effects in reactions of phosphatases. Biochemistry. 39: 9451-8. PMID 10924140 DOI: 10.1021/Bi000899X  0.604
2000 Stec B, Holtz KM, Kantrowitz ER. A revised mechanism for the alkaline phosphatase reaction involving three metal ions. Journal of Molecular Biology. 299: 1303-11. PMID 10873454 DOI: 10.1006/Jmbi.2000.3799  0.648
2000 Holtz KM, Stec B, Myers JK, Antonelli SM, Widlanski TS, Kantrowitz ER. Alternate modes of binding in two crystal structures of alkaline phosphatase-inhibitor complexes. Protein Science : a Publication of the Protein Society. 9: 907-15. PMID 10850800 DOI: 10.1110/Ps.9.5.907  0.587
1999 Holtz KM, Kantrowitz ER. The mechanism of the alkaline phosphatase reaction: insights from NMR, crystallography and site-specific mutagenesis. Febs Letters. 462: 7-11. PMID 10580082 DOI: 10.1016/S0014-5793(99)01448-9  0.668
1999 Holtz KM, Stec B, Kantrowitz ER. A model of the transition state in the alkaline phosphatase reaction. The Journal of Biological Chemistry. 274: 8351-4. PMID 10085061 DOI: 10.1074/Jbc.274.13.8351  0.64
1997 Widlanski TS, Myers JK, Stec B, Holtz KM, Kantrowitz ER. The road less travelled: taming phosphatases. Chemistry & Biology. 4: 489-92. PMID 9263635 DOI: 10.1016/S1074-5521(97)90319-7  0.474
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