Darwin J. Prockop - Publications

Affiliations: 
2000-2008 Neuroscience Tulane University School of Science and Engineering 
 2008- Texas A & M College of Medicine, Bryan, TX, United States 
Area:
Neuroscience Biology, Cell Biology
Website:
https://medicine.tamhsc.edu/faculty/prockop.html

267 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Song HB, Park SY, Ko JH, Park JW, Yoon CH, Kim DH, Kim JH, Kim MK, Lee RH, Prockop DJ, Oh JY. Mesenchymal Stromal Cells Inhibit Inflammatory Lymphangiogenesis in the Cornea by Suppressing Macrophage in a TSG-6-Dependent Manner. Molecular Therapy : the Journal of the American Society of Gene Therapy. 26: 162-172. PMID 29301108 DOI: 10.1016/J.Ymthe.2017.09.026  0.307
2017 Prockop DJ, Oh JY, Lee RH. Data against a Common Assumption: Xenogeneic Mouse Models Can Be Used to Assay Suppression of Immunity by Human MSCs. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28647464 DOI: 10.1016/J.Ymthe.2017.06.004  0.319
2017 Shigemoto-Kuroda T, Oh JY, Kim DK, Jeong HJ, Park SY, Lee HJ, Park JW, Kim TW, An SY, Prockop DJ, Lee RH. MSC-derived Extracellular Vesicles Attenuate Immune Responses in Two Autoimmune Murine Models: Type 1 Diabetes and Uveoretinitis. Stem Cell Reports. 8: 1214-1225. PMID 28494937 DOI: 10.1016/J.Stemcr.2017.04.008  0.327
2017 Ullah M, Kuroda Y, Bartosh TJ, Liu F, Zhao Q, Gregory C, Reger R, Xu J, Lee RH, Prockop DJ. iPS-derived MSCs from an expandable bank to deliver a prodrug-converting enzyme that limits growth and metastases of human breast cancers. Cell Death Discovery. 3: 16064. PMID 28179988 DOI: 10.1038/Cddiscovery.2016.64  0.326
2016 Yun YI, Park SY, Lee HJ, Ko JH, Kim MK, Wee WR, Reger RL, Gregory CA, Choi H, Fulcher SF, Prockop DJ, Oh JY. Comparison of the anti-inflammatory effects of induced pluripotent stem cell-derived and bone marrow-derived mesenchymal stromal cells in a murine model of corneal injury. Cytotherapy. PMID 27840134 DOI: 10.1016/J.Jcyt.2016.10.007  0.358
2016 Prockop DJ. The exciting prospects of new therapies with mesenchymal stromal cells. Cytotherapy. PMID 27769637 DOI: 10.1016/J.Jcyt.2016.09.008  0.352
2016 Bazhanov N, Ylostalo JH, Bartosh TJ, Tiblow A, Mohammadipoor A, Foskett A, Prockop DJ. Intraperitoneally infused human mesenchymal stem cells form aggregates with mouse immune cells and attach to peritoneal organs. Stem Cell Research & Therapy. 7: 27. PMID 26864573 DOI: 10.1186/S13287-016-0284-5  0.343
2016 Prockop DJ. Inflammation, fibrosis, and modulation of the process by mesenchymal stem/stromal cells. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 26807758 DOI: 10.1016/J.Matbio.2016.01.010  0.341
2016 Kim DK, Choi H, Nishida H, Oh JY, Gregory C, Lee RH, Yu JM, Watanabe J, An SY, Bartosh TJ, Prockop DJ. Scalable Production of a Multifunctional Protein (TSG-6) That Aggregates with Itself and the CHO Cells That Synthesize It. Plos One. 11: e0147553. PMID 26793973 DOI: 10.1371/Journal.Pone.0147553  0.317
2015 Kim DK, Nishida H, An SY, Shetty AK, Bartosh TJ, Prockop DJ. Chromatographically isolated CD63+CD81+ extracellular vesicles from mesenchymal stromal cells rescue cognitive impairments after TBI. Proceedings of the National Academy of Sciences of the United States of America. PMID 26699510 DOI: 10.1073/Pnas.1522297113  0.325
2015 Ko JH, Lee HJ, Jeong HJ, Kim MK, Wee WR, Yoon SO, Choi H, Prockop DJ, Oh JY. Mesenchymal stem/stromal cells precondition lung monocytes/macrophages to produce tolerance against allo- and autoimmunity in the eye. Proceedings of the National Academy of Sciences of the United States of America. PMID 26699483 DOI: 10.1073/Pnas.1522905113  0.304
2015 Zhao Q, Gregory CA, Lee RH, Reger RL, Qin L, Hai B, Park MS, Yoon N, Clough B, McNeill E, Prockop DJ, Liu F. MSCs derived from iPSCs with a modified protocol are tumor-tropic but have much less potential to promote tumors than bone marrow MSCs. Proceedings of the National Academy of Sciences of the United States of America. 112: 530-5. PMID 25548183 DOI: 10.1073/Pnas.1423008112  0.331
2015 Xie J, Broxmeyer HE, Feng D, Schweitzer KS, Yi R, Cook TG, Chitteti BR, Barwinska D, Traktuev DO, Van Demark MJ, Justice MJ, Ou X, Srour EF, Prockop DJ, Petrache I, et al. Human adipose-derived stem cells ameliorate cigarette smoke-induced murine myelosuppression via secretion of TSG-6. Stem Cells (Dayton, Ohio). 33: 468-78. PMID 25329668 DOI: 10.1002/Stem.1851  0.323
2014 Lee RH, Yu JM, Foskett AM, Peltier G, Reneau JC, Bazhanov N, Oh JY, Prockop DJ. TSG-6 as a biomarker to predict efficacy of human mesenchymal stem/progenitor cells (hMSCs) in modulating sterile inflammation in vivo. Proceedings of the National Academy of Sciences of the United States of America. 111: 16766-71. PMID 25385603 DOI: 10.1073/Pnas.1416121111  0.343
2014 Ylostalo JH, Bartosh TJ, Tiblow A, Prockop DJ. Unique characteristics of human mesenchymal stromal/progenitor cells pre-activated in 3-dimensional cultures under different conditions. Cytotherapy. 16: 1486-500. PMID 25231893 DOI: 10.1016/J.Jcyt.2014.07.010  0.345
2014 McFerrin HE, Olson SD, Gutschow MV, Semon JA, Sullivan DE, Prockop DJ. Rapidly self-renewing human multipotent marrow stromal cells (hMSC) express sialyl Lewis X and actively adhere to arterial endothelium in a chick embryo model system. Plos One. 9: e105411. PMID 25144321 DOI: 10.1371/Journal.Pone.0105411  0.332
2014 Prockop DJ, Prockop SE, Bertoncello I. Are clinical trials with mesenchymal stem/progenitor cells too far ahead of the science? Lessons from experimental hematology. Stem Cells (Dayton, Ohio). 32: 3055-61. PMID 25100155 DOI: 10.1002/Stem.1806  0.322
2014 Reger RL, Prockop DJ. Should publications on mesenchymal stem/progenitor cells include in-process data on the preparation of the cells? Stem Cells Translational Medicine. 3: 632-5. PMID 24692588 DOI: 10.5966/Sctm.2013-0203  0.333
2014 Kim H, Darwish I, Monroy MF, Prockop DJ, Liles WC, Kain KC. Mesenchymal stromal (stem) cells suppress pro-inflammatory cytokine production but fail to improve survival in experimental staphylococcal toxic shock syndrome. Bmc Immunology. 15: 1. PMID 24423010 DOI: 10.1186/1471-2172-15-1  0.32
2013 Bartosh TJ, Ylöstalo JH, Bazhanov N, Kuhlman J, Prockop DJ. Dynamic compaction of human mesenchymal stem/precursor cells into spheres self-activates caspase-dependent IL1 signaling to enhance secretion of modulators of inflammation and immunity (PGE2, TSG6, and STC1). Stem Cells (Dayton, Ohio). 31: 2443-56. PMID 23922312 DOI: 10.1002/Stem.1499  0.346
2013 Weiss DJ, Bates JH, Gilbert T, Liles WC, Lutzko C, Rajagopal J, Prockop D. Stem cells and cell therapies in lung biology and diseases: conference report. Annals of the American Thoracic Society. 10: S25-44. PMID 23869447 DOI: 10.1513/Annalsats.201304-089Aw  0.3
2013 Watanabe J, Shetty AK, Hattiangady B, Kim DK, Foraker JE, Nishida H, Prockop DJ. Administration of TSG-6 improves memory after traumatic brain injury in mice. Neurobiology of Disease. 59: 86-99. PMID 23851308 DOI: 10.1016/J.Nbd.2013.06.017  0.764
2013 Prockop DJ. Further proof for an unpopular concept: a single cell from bone marrow can serve as a stem cell for both hematopoiesis and osteogenesis. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1116-7. PMID 23728255 DOI: 10.1038/Mt.2013.103  0.329
2013 Prockop DJ. Concise review: two negative feedback loops place mesenchymal stem/stromal cells at the center of early regulators of inflammation. Stem Cells (Dayton, Ohio). 31: 2042-6. PMID 23681848 DOI: 10.1002/Stem.1400  0.31
2012 Lee RH, Yoon N, Reneau JC, Prockop DJ. Preactivation of human MSCs with TNF-α enhances tumor-suppressive activity. Cell Stem Cell. 11: 825-35. PMID 23142520 DOI: 10.1016/J.Stem.2012.10.001  0.314
2012 Mao JJ, Robey PG, Prockop DJ. Stem cells in the face: tooth regeneration and beyond. Cell Stem Cell. 11: 291-301. PMID 22958928 DOI: 10.1016/J.Stem.2012.08.010  0.317
2012 Oh JY, Lee RH, Yu JM, Ko JH, Lee HJ, Ko AY, Roddy GW, Prockop DJ. Intravenous mesenchymal stem cells prevented rejection of allogeneic corneal transplants by aborting the early inflammatory response. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 2143-52. PMID 22929658 DOI: 10.1038/Mt.2012.165  0.321
2012 Prockop DJ. A long-awaited discovery: hypoxia prevents mouse cells from undergoing spontaneous p53-dependent transformation. Cytotherapy. 14: 1029-31. PMID 22909278 DOI: 10.3109/14653249.2012.718887  0.305
2012 Horie M, Choi H, Lee RH, Reger RL, Ylostalo J, Muneta T, Sekiya I, Prockop DJ. Intra-articular injection of human mesenchymal stem cells (MSCs) promote rat meniscal regeneration by being activated to express Indian hedgehog that enhances expression of type II collagen. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 20: 1197-207. PMID 22750747 DOI: 10.1016/J.Joca.2012.06.002  0.345
2012 Horie M, Driscoll MD, Sampson HW, Sekiya I, Caroom CT, Prockop DJ, Thomas DB. Implantation of allogenic synovial stem cells promotes meniscal regeneration in a rabbit meniscal defect model. The Journal of Bone and Joint Surgery. American Volume. 94: 701-12. PMID 22517386 DOI: 10.2106/Jbjs.K.00176  0.344
2012 Prockop DJ, Oh JY. Medical therapies with adult stem/progenitor cells (MSCs): a backward journey from dramatic results in vivo to the cellular and molecular explanations. Journal of Cellular Biochemistry. 113: 1460-9. PMID 22213121 DOI: 10.1002/Jcb.24046  0.333
2012 Ohkouchi S, Block GJ, Katsha AM, Kanehira M, Ebina M, Kikuchi T, Saijo Y, Nukiwa T, Prockop DJ. Mesenchymal stromal cells protect cancer cells from ROS-induced apoptosis and enhance the Warburg effect by secreting STC1. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 417-23. PMID 22146344 DOI: 10.1038/Mt.2011.259  0.307
2012 Scheibe F, Gladow N, Mergenthaler P, Tucker AH, Meisel A, Prockop DJ, Priller J. Nonviral gene delivery of erythropoietin by mesenchymal stromal cells. Gene Therapy. 19: 550-60. PMID 21956691 DOI: 10.1038/Gt.2011.139  0.372
2011 Foraker JE, Oh JY, Ylostalo JH, Lee RH, Watanabe J, Prockop DJ. Cross-talk between human mesenchymal stem/progenitor cells (MSCs) and rat hippocampal slices in LPS-stimulated cocultures: the MSCs are activated to secrete prostaglandin E2. Journal of Neurochemistry. 119: 1052-63. PMID 21954847 DOI: 10.1111/J.1471-4159.2011.07511.X  0.776
2011 Roddy GW, Oh JY, Lee RH, Bartosh TJ, Ylostalo J, Coble K, Rosa RH, Prockop DJ. Action at a distance: systemically administered adult stem/progenitor cells (MSCs) reduce inflammatory damage to the cornea without engraftment and primarily by secretion of TNF-α stimulated gene/protein 6. Stem Cells (Dayton, Ohio). 29: 1572-9. PMID 21837654 DOI: 10.1002/Stem.708  0.351
2011 Choi H, Lee RH, Bazhanov N, Oh JY, Prockop DJ. Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-κB signaling in resident macrophages. Blood. 118: 330-8. PMID 21551236 DOI: 10.1182/Blood-2010-12-327353  0.309
2011 Shoji M, Oskowitz A, Malone CD, Prockop DJ, Pochampally R. Human mesenchymal stromal cells (MSCs) reduce neointimal hyperplasia in a mouse model of flow-restriction by transient suppression of anti-inflammatory cytokines. Journal of Atherosclerosis and Thrombosis. 18: 464-74. PMID 21307612 DOI: 10.5551/Jat.6213  0.311
2011 Robinson AP, Foraker JE, Ylostalo J, Prockop DJ. Human stem/progenitor cells from bone marrow enhance glial differentiation of rat neural stem cells: a role for transforming growth factor β and Notch signaling. Stem Cells and Development. 20: 289-300. PMID 20575640 DOI: 10.1089/Scd.2009.0444  0.777
2010 Uccelli A, Prockop DJ. Why should mesenchymal stem cells (MSCs) cure autoimmune diseases? Current Opinion in Immunology. 22: 768-74. PMID 21093239 DOI: 10.1016/J.Coi.2010.10.012  0.349
2010 Oh JY, Roddy GW, Choi H, Lee RH, Ylöstalo JH, Rosa RH, Prockop DJ. Anti-inflammatory protein TSG-6 reduces inflammatory damage to the cornea following chemical and mechanical injury. Proceedings of the National Academy of Sciences of the United States of America. 107: 16875-80. PMID 20837529 DOI: 10.1073/Pnas.1012451107  0.332
2010 Prockop DJ, Brenner M, Fibbe WE, Horwitz E, Le Blanc K, Phinney DG, Simmons PJ, Sensebe L, Keating A. Defining the risks of mesenchymal stromal cell therapy. Cytotherapy. 12: 576-8. PMID 20735162 DOI: 10.3109/14653249.2010.507330  0.302
2010 Prockop DJ, Kota DJ, Bazhanov N, Reger RL. Evolving paradigms for repair of tissues by adult stem/progenitor cells (MSCs). Journal of Cellular and Molecular Medicine. 14: 2190-9. PMID 20716123 DOI: 10.1111/J.1582-4934.2010.01151.X  0.36
2010 Bartosh TJ, Ylöstalo JH, Mohammadipoor A, Bazhanov N, Coble K, Claypool K, Lee RH, Choi H, Prockop DJ. Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties. Proceedings of the National Academy of Sciences of the United States of America. 107: 13724-9. PMID 20643923 DOI: 10.1073/Pnas.1008117107  0.361
2010 Larson BL, Ylostalo J, Lee RH, Gregory C, Prockop DJ. Sox11 is expressed in early progenitor human multipotent stromal cells and decreases with extensive expansion of the cells. Tissue Engineering. Part A. 16: 3385-94. PMID 20626275 DOI: 10.1089/Ten.Tea.2010.0085  0.373
2010 Prockop DJ. Defining the probability that a cell therapy will produce a malignancy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1249-50. PMID 20596063 DOI: 10.1038/Mt.2010.99  0.357
2010 Snyder BR, Chiu AM, Prockop DJ, Chan AW. Human multipotent stromal cells (MSCs) increase neurogenesis and decrease atrophy of the striatum in a transgenic mouse model for Huntington's disease. Plos One. 5: e9347. PMID 20179764 DOI: 10.1371/Journal.Pone.0009347  0.755
2010 Fischer-Valuck BW, Barrilleaux BL, Phinney DG, Russell KC, Prockop DJ, O'Connor KC. Migratory response of mesenchymal stem cells to macrophage migration inhibitory factor and its antagonist as a function of colony-forming efficiency. Biotechnology Letters. 32: 19-27. PMID 19705068 DOI: 10.1007/S10529-009-0110-6  0.346
2009 Lee RH, Pulin AA, Seo MJ, Kota DJ, Ylostalo J, Larson BL, Semprun-Prieto L, Delafontaine P, Prockop DJ. Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6. Cell Stem Cell. 5: 54-63. PMID 19570514 DOI: 10.1016/J.Stem.2009.05.003  0.32
2009 Prockop DJ. Repair of tissues by adult stem/progenitor cells (MSCs): controversies, myths, and changing paradigms. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 939-46. PMID 19337235 DOI: 10.1038/Mt.2009.62  0.327
2009 Block GJ, Ohkouchi S, Fung F, Frenkel J, Gregory C, Pochampally R, DiMattia G, Sullivan DE, Prockop DJ. Multipotent stromal cells are activated to reduce apoptosis in part by upregulation and secretion of stanniocalcin-1. Stem Cells (Dayton, Ohio). 27: 670-81. PMID 19267325 DOI: 10.1002/stem.20080742  0.329
2009 Barrilleaux BL, Phinney DG, Fischer-Valuck BW, Russell KC, Wang G, Prockop DJ, O'Connor KC. Small-molecule antagonist of macrophage migration inhibitory factor enhances migratory response of mesenchymal stem cells to bronchial epithelial cells. Tissue Engineering. Part A. 15: 2335-46. PMID 19260777 DOI: 10.1089/Ten.Tea.2008.0434  0.352
2009 Lee RH, Seo MJ, Pulin AA, Gregory CA, Ylostalo J, Prockop DJ. The CD34-like protein PODXL and alpha6-integrin (CD49f) identify early progenitor MSCs with increased clonogenicity and migration to infarcted heart in mice. Blood. 113: 816-26. PMID 18818395 DOI: 10.1182/Blood-2007-12-128702  0.364
2008 Garnero P, Schott AM, Prockop D, Chevrel G. Bone turnover and type I collagen C-telopeptide isomerization in adult osteogenesis imperfecta: associations with collagen gene mutations. Bone. 44: 461-6. PMID 19071236 DOI: 10.1016/J.Bone.2008.11.006  0.319
2008 Zeitouni S, Ford BS, Harris SM, Whitney MJ, Gregory CA, Prockop DJ. Pharmaceutical induction of ApoE secretion by multipotent mesenchymal stromal cells (MSCs). Bmc Biotechnology. 8: 75. PMID 18823563 DOI: 10.1186/1472-6750-8-75  0.332
2008 Ohtaki H, Ylostalo JH, Foraker JE, Robinson AP, Reger RL, Shioda S, Prockop DJ. Stem/progenitor cells from bone marrow decrease neuronal death in global ischemia by modulation of inflammatory/immune responses. Proceedings of the National Academy of Sciences of the United States of America. 105: 14638-43. PMID 18794523 DOI: 10.1073/Pnas.0803670105  0.782
2008 Ylöstalo J, Bazhanov N, Prockop DJ. Reversible commitment to differentiation by human multipotent stromal cells in single-cell-derived colonies. Experimental Hematology. 36: 1390-402. PMID 18619725 DOI: 10.1016/J.Exphem.2008.05.003  0.352
2008 Ylöstalo J, Pochampally R, Prockop DJ. Assays of MSCs with microarrays. Methods in Molecular Biology (Clifton, N.J.). 449: 133-51. PMID 18370089 DOI: 10.1007/978-1-60327-169-1_10  0.301
2008 Spees JL, Whitney MJ, Sullivan DE, Lasky JA, Laboy M, Ylostalo J, Prockop DJ. Bone marrow progenitor cells contribute to repair and remodeling of the lung and heart in a rat model of progressive pulmonary hypertension. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1226-36. PMID 18032636 DOI: 10.1096/Fj.07-8076Com  0.316
2008 Larson BL, Ylöstalo J, Prockop DJ. Human multipotent stromal cells undergo sharp transition from division to development in culture. Stem Cells (Dayton, Ohio). 26: 193-201. PMID 17916801 DOI: 10.1634/Stemcells.2007-0524  0.362
2007 Lee N, Smolarz AJ, Olson S, David O, Reiser J, Kutner R, Daw NC, Prockop DJ, Horwitz EM, Gregory CA. A potential role for Dkk-1 in the pathogenesis of osteosarcoma predicts novel diagnostic and treatment strategies. British Journal of Cancer. 97: 1552-9. PMID 17987039 DOI: 10.1038/Sj.Bjc.6604069  0.33
2007 Phinney DG, Prockop DJ. Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair--current views. Stem Cells (Dayton, Ohio). 25: 2896-902. PMID 17901396 DOI: 10.1634/Stemcells.2007-0637  0.366
2007 Prockop DJ. "Stemness" does not explain the repair of many tissues by mesenchymal stem/multipotent stromal cells (MSCs) Clinical Pharmacology and Therapeutics. 82: 241-243. PMID 17700588 DOI: 10.1038/Sj.Clpt.6100313  0.338
2007 Pochampally RR, Ylostalo J, Penfornis P, Matz RR, Smith JR, Prockop DJ. Histamine receptor H1 and dermatopontin: new downstream targets of the vitamin D receptor. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 22: 1338-49. PMID 17547532 DOI: 10.1359/Jbmr.070605  0.321
2007 Spees JL, Pociask DA, Sullivan DE, Whitney MJ, Lasky JA, Prockop DJ, Brody AR. Engraftment of bone marrow progenitor cells in a rat model of asbestos-induced pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine. 176: 385-94. PMID 17496228 DOI: 10.1164/Rccm.200607-1004Oc  0.317
2007 Hung SC, Pochampally RR, Hsu SC, Sanchez C, Chen SC, Spees J, Prockop DJ. Short-term exposure of multipotent stromal cells to low oxygen increases their expression of CX3CR1 and CXCR4 and their engraftment in vivo. Plos One. 2: e416. PMID 17476338 DOI: 10.1371/Journal.Pone.0000416  0.374
2007 Iso Y, Spees JL, Serrano C, Bakondi B, Pochampally R, Song YH, Sobel BE, Delafontaine P, Prockop DJ. Multipotent human stromal cells improve cardiac function after myocardial infarction in mice without long-term engraftment. Biochemical and Biophysical Research Communications. 354: 700-6. PMID 17257581 DOI: 10.1016/J.Bbrc.2007.01.045  0.311
2007 Marini JC, Forlino A, Cabral WA, Barnes AM, San Antonio JD, Milgrom S, Hyland JC, Körkkö J, Prockop DJ, De Paepe A, Coucke P, Symoens S, Glorieux FH, Roughley PJ, Lund AM, et al. Consortium for osteogenesis imperfecta mutations in the helical domain of type I collagen: regions rich in lethal mutations align with collagen binding sites for integrins and proteoglycans. Human Mutation. 28: 209-21. PMID 17078022 DOI: 10.1002/Humu.20429  0.315
2007 Tolar J, Nauta AJ, Osborn MJ, Panoskaltsis Mortari A, McElmurry RT, Bell S, Xia L, Zhou N, Riddle M, Schroeder TM, Westendorf JJ, McIvor RS, Hogendoorn PC, Szuhai K, Oseth L, ... ... Prockop DJ, et al. Sarcoma derived from cultured mesenchymal stem cells. Stem Cells (Dayton, Ohio). 25: 371-9. PMID 17038675 DOI: 10.1634/Stemcells.2005-0620  0.352
2006 Barrilleaux B, Phinney DG, Prockop DJ, O'Connor KC. Review: ex vivo engineering of living tissues with adult stem cells. Tissue Engineering. 12: 3007-19. PMID 17518617 DOI: 10.1089/Ten.2006.12.3007  0.342
2006 Peister A, Zeitouni S, Pfankuch T, Reger RL, Prockop DJ, Raber J. Novel object recognition in Apoe(-/-) mice improved by neonatal implantation of wild-type multipotential stromal cells. Experimental Neurology. 201: 266-9. PMID 16808914 DOI: 10.1016/J.Expneurol.2006.03.023  0.301
2006 Ylöstalo J, Smith JR, Pochampally RR, Matz R, Sekiya I, Larson BL, Vuoristo JT, Prockop DJ. Use of differentiating adult stem cells (marrow stromal cells) to identify new downstream target genes for transcription factors. Stem Cells (Dayton, Ohio). 24: 642-52. PMID 16439615 DOI: 10.1634/Stemcells.2005-0270  0.329
2006 Gunn WG, Conley A, Deininger L, Olson SD, Prockop DJ, Gregory CA. A crosstalk between myeloma cells and marrow stromal cells stimulates production of DKK1 and interleukin-6: a potential role in the development of lytic bone disease and tumor progression in multiple myeloma. Stem Cells (Dayton, Ohio). 24: 986-91. PMID 16293576 DOI: 10.1634/Stemcells.2005-0220  0.344
2006 Lee RH, Hsu SC, Munoz J, Jung JS, Lee NR, Pochampally R, Prockop DJ. A subset of human rapidly self-renewing marrow stromal cells preferentially engraft in mice. Blood. 107: 2153-61. PMID 16278305 DOI: 10.1182/Blood-2005-07-2701  0.362
2006 Tolar J, Nauta AJ, Osborn MJ, Panoskaltsis-Mortari A, McElmurry RT, Bell S, Xia L, Zhou N, Riddle M, Schroeder TM, Westendorf JJ, McIvor RS, Hogendoom PC, Szuhai K, Oseth L, ... ... Prockop DJ, et al. Osteosarcoma Derived from Cultured Mesenchymal Stem Cells. Blood. 108: 2554-2554. DOI: 10.1182/Blood.V108.11.2554.2554  0.358
2006 Munoz JR, Stoutenger BR, Robinson AP, Spees JL, Prockop DJ. Erratum: Human stem/progenitor cells from bone marrow promote neurogenesis of endogenous neural stem cells in the hippocampus of mice (Proceedings of the National Academy of Sciences of the United States of America (December 13, 2005) 102, 50 (18171-18176) DOI: 10.1073/pnas.0508945102) Proceedings of the National Academy of Sciences of the United States of America. 103: 2000-2002. DOI: 10.1073/Pnas.0510800103  0.332
2005 Munoz JR, Stoutenger BR, Robinson AP, Spees JL, Prockop DJ. Human stem/progenitor cells from bone marrow promote neurogenesis of endogenous neural stem cells in the hippocampus of mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 18171-6. PMID 16330757 DOI: 10.1073/Pnas.0508945102  0.366
2005 Gregory CA, Ylostalo J, Prockop DJ. Adult bone marrow stem/progenitor cells (MSCs) are preconditioned by microenvironmental "niches" in culture: a two-stage hypothesis for regulation of MSC fate. Science's Stke : Signal Transduction Knowledge Environment. 2005: pe37. PMID 16046665 DOI: 10.1126/Stke.2942005Pe37  0.369
2005 Gregory CA, Gunn WG, Reyes E, Smolarz AJ, Munoz J, Spees JL, Prockop DJ. How Wnt signaling affects bone repair by mesenchymal stem cells from the bone marrow. Annals of the New York Academy of Sciences. 1049: 97-106. PMID 15965110 DOI: 10.1196/Annals.1334.010  0.346
2005 Gregory CA, Prockop DJ, Spees JL. Non-hematopoietic bone marrow stem cells: molecular control of expansion and differentiation. Experimental Cell Research. 306: 330-5. PMID 15925588 DOI: 10.1016/J.Yexcr.2005.03.018  0.361
2005 Nieminen J, Sahlman J, Hirvonen T, Jämsä T, Tuukkanen J, Kovanen V, Kröger H, Jurvelin J, Arita M, Li SW, Prockop DJ, Hyttinen MM, Helminen HJ, Lapveteläinen T, Puustjärvi K. Abnormal response to physical activity in femurs after heterozygous inactivation of one allele of the Col2a1 gene for type II collagen in mice. Calcified Tissue International. 77: 104-12. PMID 15920676 DOI: 10.1007/S00223-004-0069-1  0.302
2005 Pochampally RR, Horwitz EM, DiGirolamo CM, Stokes DS, Prockop DJ. Correction of a mineralization defect by overexpression of a wild-type cDNA for COL1A1 in marrow stromal cells (MSCs) from a patient with osteogenesis imperfecta: a strategy for rescuing mutations that produce dominant-negative protein defects. Gene Therapy. 12: 1119-25. PMID 15815702 DOI: 10.1038/Sj.Gt.3302514  0.394
2005 Sekiya I, Larson BL, Vuoristo JT, Reger RL, Prockop DJ. Comparison of effect of BMP-2, -4, and -6 on in vitro cartilage formation of human adult stem cells from bone marrow stroma. Cell and Tissue Research. 320: 269-76. PMID 15778851 DOI: 10.1007/S00441-004-1075-3  0.388
2005 Wang G, Bunnell BA, Painter RG, Quiniones BC, Tom S, Lanson NA, Spees JL, Bertucci D, Peister A, Weiss DJ, Valentine VG, Prockop DJ, Kolls JK. Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: potential therapy for cystic fibrosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 186-91. PMID 15615854 DOI: 10.1073/Pnas.0406266102  0.326
2005 Gregory CA, Perry AS, Reyes E, Conley A, Gunn WG, Prockop DJ. Dkk-1-derived synthetic peptides and lithium chloride for the control and recovery of adult stem cells from bone marrow. The Journal of Biological Chemistry. 280: 2309-23. PMID 15504735 DOI: 10.1074/Jbc.M406275200  0.353
2005 Tolar J, Osborn MJ, Panoskaltsis-Mortari A, McElmurry RT, Bell S, Xia L, Riddle M, Schroeder TM, Westendorf JJ, McIvor RS, Oseth L, Hirsch B, Yant SR, Kay MA, Peister A, ... Prockop DJ, et al. Mesenchymal Cancer Cells Can Arise from Ex Vivo Modified Mesenchymal Stem Cells. Blood. 106: 4326-4326. DOI: 10.1182/Blood.V106.11.4326.4326  0.358
2004 Sahlman J, Pitkänen MT, Prockop DJ, Arita M, Li SW, Helminen HJ, Långsjö TK, Puustjärvi K, Lammi MJ. A human COL2A1 gene with an Arg519Cys mutation causes osteochondrodysplasia in transgenic mice. Arthritis and Rheumatism. 50: 3153-60. PMID 15476249 DOI: 10.1002/Art.20552  0.307
2004 Smith JR, Pochampally R, Perry A, Hsu SC, Prockop DJ. Isolation of a highly clonogenic and multipotential subfraction of adult stem cells from bone marrow stroma. Stem Cells (Dayton, Ohio). 22: 823-31. PMID 15342946 DOI: 10.1634/Stemcells.22-5-823  0.365
2004 Pochampally RR, Neville BT, Schwarz EJ, Li MM, Prockop DJ. Rat adult stem cells (marrow stromal cells) engraft and differentiate in chick embryos without evidence of cell fusion. Proceedings of the National Academy of Sciences of the United States of America. 101: 9282-5. PMID 15197249 DOI: 10.1073/Pnas.0401558101  0.341
2004 Prockop DJ. Targeting gene therapy for osteogenesis imperfecta. The New England Journal of Medicine. 350: 2302-4. PMID 15163783 DOI: 10.1056/Nejmcibr040806  0.346
2004 Spees JL, Gregory CA, Singh H, Tucker HA, Peister A, Lynch PJ, Hsu SC, Smith J, Prockop DJ. Internalized antigens must be removed to prepare hypoimmunogenic mesenchymal stem cells for cell and gene therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 747-56. PMID 15120336 DOI: 10.1016/J.Ymthe.2004.02.012  0.372
2004 Sekiya I, Larson BL, Vuoristo JT, Cui JG, Prockop DJ. Adipogenic differentiation of human adult stem cells from bone marrow stroma (MSCs). Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 19: 256-64. PMID 14969395 DOI: 10.1359/Jbmr.0301220  0.375
2004 Peister A, Mellad JA, Wang M, Tucker HA, Prockop DJ. Stable transfection of MSCs by electroporation. Gene Therapy. 11: 224-8. PMID 14712307 DOI: 10.1038/Sj.Gt.3302163  0.352
2004 Pochampally RR, Smith JR, Ylostalo J, Prockop DJ. Serum deprivation of human marrow stromal cells (hMSCs) selects for a subpopulation of early progenitor cells with enhanced expression of OCT-4 and other embryonic genes Blood. 103: 1647-1652. PMID 14630823 DOI: 10.1182/Blood-2003-06-1967  0.37
2004 Peister A, Mellad JA, Larson BL, Hall BM, Gibson LF, Prockop DJ. Adult stem cells from bone marrow (MSCs) isolated from different strains of inbred mice vary in surface epitopes, rates of proliferation, and differentiation potential. Blood. 103: 1662-8. PMID 14592819 DOI: 10.1182/Blood-2003-09-3070  0.352
2004 Prockop DJ. Time to end the stem cell wars? Blood. 104: 3421-3422. DOI: 10.1182/Blood-2004-09-3478  0.324
2004 Wang G, Bunnell BA, Painter RG, Tom S, Lanson NA, Spees JL, Bertucci D, Weiss DJ, Valentine VG, Prockop DJ, Kolls JK. 514. Potential of Bone Marrow Mesenchymal Stem Cells for Cystic Fibrosis Therapy Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.455  0.388
2003 Prockop DJ, Gregory CA, Spees JL. One strategy for cell and gene therapy: harnessing the power of adult stem cells to repair tissues. Proceedings of the National Academy of Sciences of the United States of America. 100: 11917-23. PMID 13679583 DOI: 10.1073/Pnas.1834138100  0.368
2003 Gregory CA, Singh H, Perry AS, Prockop DJ. The Wnt signaling inhibitor dickkopf-1 is required for reentry into the cell cycle of human adult stem cells from bone marrow. The Journal of Biological Chemistry. 278: 28067-78. PMID 12740383 DOI: 10.1074/Jbc.M300373200  0.346
2003 Spees JL, Olson SD, Ylostalo J, Lynch PJ, Smith J, Perry A, Peister A, Wang MY, Prockop DJ. Differentiation, cell fusion, and nuclear fusion during ex vivo repair of epithelium by human adult stem cells from bone marrow stroma. Proceedings of the National Academy of Sciences of the United States of America. 100: 2397-402. PMID 12606728 DOI: 10.1073/Pnas.0437997100  0.364
2002 Sekiya I, Larson BL, Smith JR, Pochampally R, Cui JG, Prockop DJ. Expansion of human adult stem cells from bone marrow stroma: conditions that maximize the yields of early progenitors and evaluate their quality. Stem Cells (Dayton, Ohio). 20: 530-41. PMID 12456961 DOI: 10.1634/Stemcells.20-6-530  0.35
2002 Sekiya I, Vuoristo JT, Larson BL, Prockop DJ. In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis. Proceedings of the National Academy of Sciences of the United States of America. 99: 4397-402. PMID 11917104 DOI: 10.1073/Pnas.052716199  0.351
2002 Hofstetter CP, Schwarz EJ, Hess D, Widenfalk J, El Manira A, Prockop DJ, Olson L. Marrow stromal cells form guiding strands in the injured spinal cord and promote recovery. Proceedings of the National Academy of Sciences of the United States of America. 99: 2199-204. PMID 11854516 DOI: 10.1073/Pnas.042678299  0.302
2002 Colige A, Vandenberghe I, Thiry M, Lambert CA, Van Beeumen J, Li SW, Prockop DJ, Lapiere CM, Nusgens BV. Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3. The Journal of Biological Chemistry. 277: 5756-66. PMID 11741898 DOI: 10.1074/Jbc.M105601200  0.342
2001 Prockop DJ, Sekiya I, Colter DC. Isolation and characterization of rapidly self-renewing stem cells from cultures of human marrow stromal cells Cytotherapy. 3: 393-396. PMID 11953019 DOI: 10.1080/146532401753277229  0.363
2001 Sahlman J, Inkinen R, Hirvonen T, Lammi MJ, Lammi PE, Nieminen J, Lapveteläinen T, Prockop DJ, Arita M, Li SW, Hyttinen MM, Helminen HJ, Puustjärvi K. Premature vertebral endplate ossification and mild disc degeneration in mice after inactivation of one allele belonging to the Col2a1 gene for Type II collagen. Spine. 26: 2558-65. PMID 11725236 DOI: 10.1097/00007632-200112010-00008  0.312
2001 Li SW, Takanosu M, Arita M, Bao Y, Ren ZX, Maier A, Prockop DJ, Mayne R. Targeted disruption of Col11a2 produces a mild cartilage phenotype in transgenic mice: comparison with the human disorder otospondylomegaepiphyseal dysplasia (OSMED). Developmental Dynamics : An Official Publication of the American Association of Anatomists. 222: 141-52. PMID 11668593 DOI: 10.1002/Dvdy.1178  0.318
2001 Schwarz EJ, Reger RL, Alexander GM, Class R, Azizi SA, Prockop DJ. Rat marrow stromal cells rapidly transduced with a self-inactivating retrovirus synthesize L-DOPA in vitro. Gene Therapy. 8: 1214-23. PMID 11509954 DOI: 10.1038/Sj.Gt.3301517  0.337
2001 Prockop DJ. Stem cell research has only just begun [2] Science. 293: 211-212. PMID 11452973 DOI: 10.1126/Science.293.5528.211C  0.321
2001 Colter DC, Sekiya I, Prockop DJ. Identification of a subpopulation of rapidly self-renewing and multipotential adult stem cells in colonies of human marrow stromal cells Proceedings of the National Academy of Sciences of the United States of America. 98: 7841-7845. PMID 11427725 DOI: 10.1073/Pnas.141221698  0.35
2001 Sekiya I, Colter DC, Prockop DJ. BMP-6 enhances chondrogenesis in a subpopulation of human marrow stromal cells Biochemical and Biophysical Research Communications. 284: 411-418. PMID 11394894 DOI: 10.1006/Bbrc.2001.4898  0.368
2001 Javazon EH, Colter DC, Schwarz EJ, Prockop DJ. Rat marrow stromal cells are more sensitive to plating density and expand more rapidly from single-cell-derived colonies than human marrow stromal cells. Stem Cells (Dayton, Ohio). 19: 219-25. PMID 11359947 DOI: 10.1634/Stemcells.19-3-219  0.339
2001 Deng W, Obrocka M, Fischer I, Prockop DJ. In vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP Biochemical and Biophysical Research Communications. 282: 148-152. PMID 11263984 DOI: 10.1006/Bbrc.2001.4570  0.351
2000 Woodbury D, Schwarz EJ, Prockop DJ, Black IB. Adult rat and human bone marrow stromal cells differentiate into neurons. Journal of Neuroscience Research. 61: 364-70. PMID 10931522 DOI: 10.1002/1097-4547(20000815)61:4<364::Aid-Jnr2>3.0.Co;2-C  0.348
2000 Körkkö J, Cohn DH, Ala-Kokko L, Krakow D, Prockop DJ. Widely distributed mutations in the COL2A1 gene produce achondrogenesis type II/hypochondrogenesis. American Journal of Medical Genetics. 92: 95-100. PMID 10797431 DOI: 10.1002/(Sici)1096-8628(20000515)92:2<95::Aid-Ajmg3>3.0.Co;2-9  0.301
2000 Yuan CM, Ala-Kokko L, Le Guellec D, Franc S, Fertala A, Khillan JS, Sokolov BP, Prockop DJ. Lack of a phenotype in transgenic mice aberrantly expressing COL2A1 mRNA because of highly selective post-transcriptional down-regulation. The Biochemical Journal. 345: 377-84. PMID 10620515 DOI: 10.1042/Bj3450377  0.333
2000 Digirolamo CM, Stokes D, Colter D, Phinney DG, Class R, Prockop DJ. Propagation and senescence of human marrow stromal cells in culture: a simple colony-forming assay identifies samples with the greatest potential to propagate and differentiate. British Journal of Haematology. 107: 275-81. PMID 10583212 DOI: 10.1046/J.1365-2141.1999.01715.X  0.344
2000 Colter DC, Class R, DiGirolamo CM, Prockop DJ. Rapid expansion of recycling stem cells in cultures of plastic-adherent cells from human bone marrow Proceedings of the National Academy of Sciences. 97: 3213-3218. DOI: 10.1073/Pnas.97.7.3213  0.342
2000 Prockop DJ, Azizi SA, Colter D, DiGirolamo C, Kopen G, Phinney DG. Potential use of stem cells from bone marrow to repair the extracellular matrix and the central nervous system Biochemical Society Transactions. 28: 341-345. DOI: 10.1042/Bst0280341  0.357
1999 Schwarz EJ, Alexander GM, Prockop DJ, Azizi SA. Multipotential marrow stromal cells transduced to produce L-DOPA: engraftment in a rat model of Parkinson disease. Human Gene Therapy. 10: 2539-49. PMID 10543618 DOI: 10.1089/10430349950016870  0.319
1999 Phinney DG, Kopen G, Righter W, Webster S, Tremain N, Prockop DJ. Donor variation in the growth properties and osteogenic potential of human marrow stromal cells. Journal of Cellular Biochemistry. 75: 424-36. PMID 10536366 DOI: 10.1002/(Sici)1097-4644(19991201)75:3<424::Aid-Jcb8>3.0.Co;2-8  0.326
1999 Annunen S, Körkkö J, Czarny M, Warman ML, Brunner HG, Kääriäinen H, Mulliken JB, Tranebjærg L, Brooks DG, Cox GF, Cruysberg JR, Curtis MA, Davenport SLH, Friedrich CA, Kaitila I, ... ... Prockop DJ, et al. Splicing mutations of 54-bp exons in the COL11A1 gene cause Marshall syndrome, but other mutations cause overlapping Marshall/Stickler phenotypes American Journal of Human Genetics. 65: 974-983. PMID 10486316 DOI: 10.1086/302585  0.437
1999 Kopen GC, Prockop DJ, Phinney DG. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proceedings of the National Academy of Sciences of the United States of America. 96: 10711-6. PMID 10485891 DOI: 10.1073/Pnas.96.19.10711  0.337
1999 Paassilta P, Pihlajamaa T, Annunen S, Brewton RG, Wood BM, Johnson CC, Liu J, Gong Y, Warman ML, Prockop DJ, Mayne R, Ala-Kokko L. Complete sequence of the 23-kilobase human COL9A3 gene. Detection of Gly-X-Y triplet deletions that represent neutral variants. The Journal of Biological Chemistry. 274: 22469-75. PMID 10428822 DOI: 10.1074/Jbc.274.32.22469  0.33
1999 Prockop DJ. Heritable osteoarthritis. Diagnosis and possible modes of cell and gene therapy Osteoarthritis and Cartilage. 7: 364-366. PMID 10419768 DOI: 10.1053/Joca.1998.0213  0.331
1999 Colige A, Sieron AL, Li SW, Schwarze U, Petty E, Wertelecki W, Wilcox W, Krakow D, Cohn DH, Reardon W, Byers PH, Lapière CM, Prockop DJ, Nusgens BV. Human Ehlers-Danlos syndrome type VII C and bovine dermatosparaxis are caused by mutations in the procollagen I N-proteinase gene. American Journal of Human Genetics. 65: 308-17. PMID 10417273 DOI: 10.1086/302504  0.321
1999 Horwitz EM, Prockop DJ, Fitzpatrick LA, Koo WW, Gordon PL, Neel M, Sussman M, Orchard P, Marx JC, Pyeritz RE, Brenner MK. Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta. Nature Medicine. 5: 309-13. PMID 10086387 DOI: 10.1038/6529  0.303
1999 Phinney DG, Kopen G, Isaacson RL, Prockop DJ. Plastic adherent stromal cells from the bone marrow of commonly used strains of inbred mice: variations in yield, growth, and differentiation. Journal of Cellular Biochemistry. 72: 570-85. PMID 10022616 DOI: 10.1002/(Sici)1097-4644(19990315)72:4<570::Aid-Jcb12>3.0.Co;2-W  0.347
1999 Kulkosky J, Laptev A, Shetty S, Srinivasan A, BouHamdan M, Prockop DJ, Pomerantz RJ. Human Immunodeficiency Virus Type 1 Vpr Alters Bone Marrow Cell Function Blood. 93: 1906-1915. DOI: 10.1182/Blood.V93.6.1906.406K11_1906_1915  0.346
1998 PROCKOP DJ, KEISER HR, SJOERDSMA A. Gastrointestinal absorption and renal excretion of hydroxyproline peptides. Lancet (London, England). 2: 527-8. PMID 14488876 DOI: 10.1016/S0140-6736(62)90400-2  0.399
1998 Myers LK, Brand DD, Ye XJ, Cremer MA, Rosloniec EF, Bodo M, Myllyharju J, Helaakoski T, Nokelainen M, Pihlajaniemi T, Kivirikko K, Yang CL, Alakokko L, Prockop DJ, Notbohm H, et al. Characterization of recombinant type II collagen: Arthritogenicity and tolerogenicity in DBA/1 mice Immunology. 95: 631-639. PMID 9893056 DOI: 10.1046/J.1365-2567.1998.00637.X  0.302
1998 Pihlajamaa T, Vuoristo MM, Annunen S, Perälä M, Prockop DJ, Ala-Kokko L. Human COL9A1 and COL9A2 genes. Two genes of 90 and 15 kb code for similar polypeptides of the same collagen molecule. Matrix Biology : Journal of the International Society For Matrix Biology. 17: 237-41. PMID 9707347 DOI: 10.1016/S0945-053X(98)90063-4  0.308
1998 Li SW, Arita M, Kopen GC, Phinney DG, Prockop DJ. A 1,064 bp fragment from the promoter region of the Col11a2 gene drives lacZ expression not only in cartilage but also in osteoblasts adjacent to regions undergoing both endochondral and intramembranous ossification in mouse embryos. Matrix Biology : Journal of the International Society For Matrix Biology. 17: 213-21. PMID 9707344 DOI: 10.1016/S0945-053X(98)90060-9  0.313
1998 Prockop DJ. What holds us together? Why do some of us fall apart? What can we do about it? Matrix Biology : Journal of the International Society For Matrix Biology. 16: 519-28. PMID 9569121 DOI: 10.1016/S0945-053X(98)90064-6  0.395
1998 Prockop DJ, Sieron AL, Li SW. Procollagen N-proteinase and procollagen C-proteinase. Two unusual metalloproteinases that are essential for procollagen processing probably have important roles in development and cell signaling. Matrix Biology : Journal of the International Society For Matrix Biology. 16: 399-408. PMID 9524360 DOI: 10.1016/S0945-053X(98)90013-0  0.312
1998 Pereira RF, O'Hara MD, Laptev AV, Halford KW, Pollard MD, Class R, Simon D, Livezey K, Prockop DJ. Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta. Proceedings of the National Academy of Sciences of the United States of America. 95: 1142-7. PMID 9448299 DOI: 10.1073/Pnas.95.3.1142  0.362
1998 Colige A, Li S, Sieron A, Cohn D, Byers P, Prockop D, Lapière C, Nusgens B. Ehlers-Danlos type VIIC in human and dermatosparaxis in cattle are caused by mutations in the procollagen i amino-peptidase gene Journal of Dermatological Science. 16: S30. DOI: 10.1016/S0923-1811(98)83176-9  0.305
1998 Prockop DJ. Marrow stromal cells as stem cells for continual renewal of nonhematopoietic tissues and as potential vectors for gene therapy Journal of Cellular Biochemistry. 284-285. DOI: 10.1002/(Sici)1097-4644(1998)72:30/31+<284::Aid-Jcb34>3.0.Co;2-I  0.345
1997 Arnold WV, Sieron AL, Fertala A, Bächinger HP, Mechling D, Prockop DJ. A cDNA cassette system for the synthesis of recombinant procollagens. Variants of procollagen II lacking a D-period are secreted as triple-helical monomers. Matrix Biology : Journal of the International Society For Matrix Biology. 16: 105-16. PMID 9314160 DOI: 10.1016/S0945-053X(97)90039-1  0.324
1997 Yang C, Li SW, Helminen HJ, Khillan JS, Bao Y, Prockop DJ. Apoptosis of chondrocytes in transgenic mice lacking collagen II. Experimental Cell Research. 235: 370-3. PMID 9299161 DOI: 10.1006/Excr.1997.3692  0.303
1997 Jimenez SA, Ala-Kokko L, Prockop DJ, Merryman CF, Shepard N, Dodge GR. Characterization of human type II procollagen and collagen-specific antibodies and their application to the study of human type II collagen processing and ultrastructure. Matrix Biology : Journal of the International Society For Matrix Biology. 16: 29-39. PMID 9181552 DOI: 10.1016/S0945-053X(97)90114-1  0.329
1997 Colige A, Li SW, Sieron AL, Nusgens BV, Prockop DJ, Lapière CM. cDNA cloning and expression of bovine procollagen I N-proteinase: a new member of the superfamily of zinc-metalloproteinases with binding sites for cells and other matrix components. Proceedings of the National Academy of Sciences of the United States of America. 94: 2374-9. PMID 9122202 DOI: 10.1073/Pnas.94.6.2374  0.337
1997 Kuivaniemi H, Tromp G, Prockop DJ. Mutations in fibrillar collagens (types I, II, III, and XI), fibril- associated collagen (type IX), and network-forming collagen (type X) cause a spectrum of disease of bone, cartilage, and blood vessels Human Mutation. 9: 300-315. PMID 9101290 DOI: 10.1002/(Sici)1098-1004(1997)9:4<300::Aid-Humu2>3.0.Co;2-9  0.312
1997 Prockop DJ. Marrow stromal cells as stem cells for nonhematopoietic tissues Science. 276: 71-74. PMID 9082988 DOI: 10.1126/Science.276.5309.71  0.366
1997 Fertala A, Ala-Kokko L, Wiaderkiewicz R, Prockop DJ. Collagen II containing a Cys substitution for arg-alpha1-519. Homotrimeric monomers containing the mutation do not assemble into fibrils but alter the self-assembly of the normal protein. The Journal of Biological Chemistry. 272: 6457-64. PMID 9045670 DOI: 10.1074/Jbc.272.10.6457  0.311
1997 Percira R, Halford K, O'hara M, Pollard M, Laptev A, Prockop D. Replacement of bone cells expressing a muated COL1A1 gene in a transgenic mouse for osteogenesis imperfecta Matrix Biology. 16: 128. DOI: 10.1016/S0945-053X(97)90063-9  0.33
1996 Vandenberg P, Vuoristo MM, Ala-Kokko L, Prockop DJ. The mouse col11a2 gene. Some transcripts from the adjacent rxr-beta gene extend into the col11a2 gene. Matrix Biology : Journal of the International Society For Matrix Biology. 15: 359-67. PMID 8981332 DOI: 10.1016/S0945-053X(96)90139-0  0.313
1996 Scott IC, Halila R, Jenkins JM, Mehan S, Apostolou S, Winqvist R, Callen DF, Prockop DJ, Peltonen L, Kadler KE. Molecular cloning, expression and chromosomal localization of a human gene encoding a 33 kDa putative metallopeptidase (PRSM1). Gene. 174: 135-43. PMID 8863740 DOI: 10.1016/0378-1119(96)00510-0  0.326
1996 Zhuang J, Tromp G, Kuivaniemi H, Castells S, Prockop DJ. Substitution of arginine for glycine at position 154 of the α1 chain of type I collagen in a variant of osteogenesis imperfecta: Comparison to previous cases with the same mutation American Journal of Medical Genetics. 61: 111-116. PMID 8669434 DOI: 10.1016/0945-053X(94)90108-2  0.304
1996 Laptev A, Phinney D, Isaacson R, Prockop D. Inhibition of marrow osteoprogenitor cell differentiation by murine osteo-blasts Matrix Biology. 15: 190. DOI: 10.1016/S0945-053X(96)90088-8  0.333
1995 Pereira RF, Hume EL, Halford KW, Prockop DJ. Bone fragility in transgenic mice expressing a mutated gene for type I procollagen (COL1A1) parallels the age-dependent phenotype of human osteogenesis imperfecta. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 10: 1837-43. PMID 8619363 DOI: 10.1002/Jbmr.5650101202  0.323
1995 Pereira RF, Halford KW, O'Hara MD, Leeper DB, Sokolov BP, Pollard MD, Bagasra O, Prockop DJ. Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice. Proceedings of the National Academy of Sciences of the United States of America. 92: 4857-61. PMID 7761413 DOI: 10.1073/Pnas.92.11.4857  0.377
1995 Bonaventure J, Cohen-Solal L, Ritvaniemi P, Van Maldergem L, Kadhom N, Delezoide AL, Maroteaux P, Prockop DJ, Ala-Kokko L. Substitution of aspartic acid for glycine at position 310 in type II collagen produces achondrogenesis II, and substitution of serine at position 805 produces hypochondrogenesis: analysis of genotype-phenotype relationships. The Biochemical Journal. 307: 823-30. PMID 7741714 DOI: 10.1042/Bj3070823  0.329
1995 Sokolov BP, Ala-Kokko L, Dhulipala R, Arita M, Khillan JS, Prockop DJ. Tissue-specific expression of the gene for type I procollagen (COL1A1) in transgenic mice. Only 476 base pairs of the promoter are required if collagen genes are used as reporters. The Journal of Biological Chemistry. 270: 9622-9. PMID 7721894 DOI: 10.1074/Jbc.270.16.9622  0.326
1995 Li SW, Prockop DJ, Helminen H, Fässler R, Lapveteläinen T, Kiraly K, Peltarri A, Arokoski J, Lui H, Arita M. Transgenic mice with targeted inactivation of the Col2 alpha 1 gene for collagen II develop a skeleton with membranous and periosteal bone but no endochondral bone. Genes & Development. 9: 2821-30. PMID 7590256 DOI: 10.1101/Gad.9.22.2821  0.337
1995 Prockop DJ, Kivirikko KI. Collagens: Molecular biology, diseases, and potentials for therapy Annual Review of Biochemistry. 64: 403-434. PMID 7574488 DOI: 10.1146/Annurev.Bi.64.070195.002155  0.36
1995 Vuristo MM, Pihlajamaa T, Vandenberg P, Prockop DJ, Ala-Kokko L. The human COL11A2 gene structure indicates that the gene has not evolved with the genes for the major fibrillar collagens. The Journal of Biological Chemistry. 270: 22873-81. PMID 7559422 DOI: 10.1074/Jbc.270.39.22873  0.319
1994 Fertala A, Sieron AL, Ganguly A, Li SW, Ala-Kokko L, Anumula KR, Prockop DJ. Synthesis of recombinant human procollagen II in a stably transfected tumour cell line (HT1080). The Biochemical Journal. 298: 31-7. PMID 8129728 DOI: 10.1042/Bj2980031  0.357
1994 Laptev AV, Lu Z, Colige A, Prockop DJ. Specific inhibition of expression of a human collagen gene (COL1A1) with modified antisense oligonucleotides. The most effective target sites are clustered in double-stranded regions of the predicted secondary structure for the mRNA. Biochemistry. 33: 11033-9. PMID 8086420 DOI: 10.1021/Bi00202A024  0.319
1994 Ganguly A, Smelt S, Mewar R, Fertala A, Sieron AL, Overhauser J, Prockop DJ. Targeted insertions of two exogenous collagen genes into both alleles of their endogenous loci in cultured human cells: the insertions are directed by relatively short fragments containing the promoters and the 5' ends of the genes. Proceedings of the National Academy of Sciences of the United States of America. 91: 7365-9. PMID 8041796 DOI: 10.1073/Pnas.91.15.7365  0.323
1994 Khillan JS, Li SW, Prockop DJ. Partial rescue of a lethal phenotype of fragile bones in transgenic mice with a chimeric antisense gene directed against a mutated collagen gene. Proceedings of the National Academy of Sciences of the United States of America. 91: 6298-302. PMID 8022775 DOI: 10.1073/Pnas.91.14.6298  0.331
1994 Ritvaniemi P, Sokolov BP, Williams CJ, Considine E, Yurgenev L, Meerson EM, Ala-Kokko L, Prockop DJ. A single base mutation in the type II procollagen gene (COL2A1) that converts glycine alpha 1-247 to serine in a family with late-onset spondyloepiphyseal dysplasia. Human Mutation. 3: 261-7. PMID 8019561 DOI: 10.1002/Humu.1380030314  0.301
1994 Prockop DJ, Kuivaniemi H, Tromp G. Molecular basis of osteogenesis imperfecta and related disorders of bone Clinics in Plastic Surgery. 21: 407-413. PMID 7924138 DOI: 10.1016/S0094-1298(20)31017-8  0.349
1994 Cassella JP, Pereira R, Khillan JS, Prockop DJ, Garrington N, Ali SY. An ultrastructural, microanalytical, and spectroscopic study of bone from a transgenic mouse with a COL1.A1 pro-alpha-1 mutation. Bone. 15: 611-9. PMID 7873289 DOI: 10.1016/8756-3282(94)90308-5  0.326
1994 Pereira RF, Halford KW, O'Hara M, Leeper D, Pollard M, Sokolov B, Prockop DJ. Type I collagen transgene used as a marker to trace donor marrow stromal cells. Tranpslanted cells persist up to five months in bone marrow, spleen, cartilage and lung Matrix Biology. 14: 407. DOI: 10.1016/0945-053X(94)90145-7  0.335
1994 Laptev A, Lu Z, Colige A, Prockop D. Specific inhibition of expression of a human collagen gene (COL1A1) with modified antisense oligonucleotides Matrix Biology. 14: 404. DOI: 10.1016/0945-053X(94)90140-6  0.322
1993 Constantinou-Deltas CD, Ladda RL, Prockop DJ. Somatic cell mosaicism: another source of phenotypic heterogeneity in nuclear families with osteogenesis imperfecta. American Journal of Medical Genetics. 45: 246-51. PMID 8456810 DOI: 10.1002/Ajmg.1320450218  0.329
1993 Pereira R, Khillan JS, Helminen HJ, Hume EL, Prockop DJ. Transgenic mice expressing a partially deleted gene for type I procollagen (COL1A1). A breeding line with a phenotype of spontaneous fractures and decreased bone collagen and mineral. The Journal of Clinical Investigation. 91: 709-16. PMID 8432871 DOI: 10.1172/Jci116252  0.301
1993 Colige A, Sokolov BP, Nugent P, Baserga R, Prockop DJ. Use of an antisense oligonucleotide to inhibit expression of a mutated human procollagen gene (COL1A1) in transfected mouse 3T3 cells. Biochemistry. 32: 7-11. PMID 8418862 DOI: 10.1021/Bi00052A002  0.338
1993 Ritvaniemi P, Hyland J, Ignatius J, Kivirikko KI, Prockop DJ, Ala-Kokko L. A fourth example suggests that premature termination codons in the COL2A1 gene are a common cause of the Stickler syndrome: analysis of the COL2A1 gene by denaturing gradient gel electrophoresis. Genomics. 17: 218-21. PMID 8406454 DOI: 10.1006/Geno.1993.1306  0.301
1993 Sokolov BP, Mays PK, Khillan JS, Prockop DJ. Tissue- and development-specific expression in transgenic mice of a type I procollagen (COL1A1) minigene construct with 2.3 kb of the promoter region and 2 kb of the 3'-flanking region. Specificity is independent of the putative regulatory sequences in the first intron. Biochemistry. 32: 9242-9. PMID 8369292 DOI: 10.1021/Bi00086A033  0.312
1993 Geddis AE, Prockop DJ. Expression of human COL1A1 gene in stably transfected HT1080 cells: The production of a thermostable homotrimer of type I collagen in a recombinant system Matrix. 13: 399-405. PMID 8246835 DOI: 10.1016/S0934-8832(11)80045-4  0.359
1993 Williams CJ, Considine EL, Knowlton RG, Reginato A, Neumann G, Harrison D, Buxton P, Jimenez S, Prockop DJ. Spondyloepiphyseal dysplasia and precocious osteoarthritis in a family with an Arg75-->Cys mutation in the procollagen type II gene (COL2A1). Human Genetics. 92: 499-505. PMID 8244341 DOI: 10.1007/Bf00216458  0.306
1993 Prockop DJ, Colige A, Helminen H, Khillan JS, Pereira R, Vandenberg P. Mutations in type 1 procollagen that cause osteogenesis imperfecta: effects of the mutations on the assembly of collagen into fibrils, the basis of phenotypic variations, and potential antisense therapies. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 8: S489-92. PMID 8122517 DOI: 10.1002/Jbmr.5650081311  0.337
1993 Zhuang J, Tromp G, Kuivaniemi H, Nakayasu K, Prockop DJ. Deletion of 19 base pairs in intron 13 of the gene for the proα2(I) chain of type-I procollagen (COL1A2) causes exon skipping in a proband with type-I osteogenesis imperfecta Human Genetics. 91: 210-216. PMID 7916744 DOI: 10.1007/Bf00218258  0.315
1991 Spotila LD, Constantinou CD, Sereda L, Ganguly A, Riggs BL, Prockop DJ. Mutation in a gene for type I procollagen (COL1A2) in a woman with postmenopausal osteoporosis: evidence for phenotypic and genotypic overlap with mild osteogenesis imperfecta. Proceedings of the National Academy of Sciences of the United States of America. 88: 5423-7. PMID 2052622 DOI: 10.1073/Pnas.88.12.5423  0.323
1991 Kadler KE, Torre-Blanco A, Adachi E, Vogel BE, Hojima Y, Prockop DJ. A type I collagen with substitution of a cysteine for glycine-748 in the alpha 1(I) chain copolymerizes with normal type I collagen and can generate fractallike structures. Biochemistry. 30: 5081-8. PMID 2036375 DOI: 10.1021/Bi00234A035  0.325
1991 Kuivaniemi H, Tromp G, Prockop DJ. Mutations in collagen genes: Causes of rare and some common diseases in humans Faseb Journal. 5: 2052-2060. PMID 2010058 DOI: 10.1096/Fasebj.5.7.2010058  0.334
1991 Vandenberg P, Khillan JS, Prockop DJ, Helminen H, Kontusaari S, Ala-Kokko L. Expression of a partially deleted gene of human type II procollagen (COL2A1) in transgenic mice produces a chondrodysplasia. Proceedings of the National Academy of Sciences of the United States of America. 88: 7640-4. PMID 1881905 DOI: 10.1073/Pnas.88.17.7640  0.338
1991 Westerhausen A, Constantinou CD, Pack M, Peng MZ, Hanning C, Olsen AS, Prockop DJ. Completion of the last half of the structure of the human gene for the Pro alpha 1 (I) chain of type I procollagen (COL1A1). Matrix (Stuttgart, Germany). 11: 375-9. PMID 1787829 DOI: 10.1016/S0934-8832(11)80191-5  0.32
1991 Sokolov BP, Prytkov AN, Tromp G, Knowlton RG, Prockop DJ. Exclusion of COL1A1, COL1A2, and COL3A1 genes as candidate genes for Ehlers-Danlos syndrome type I in one large family. Human Genetics. 88: 125-9. PMID 1684560 DOI: 10.1007/Bf00206058  0.305
1991 Ahmad NN, Ala-Kokko L, Knowlton RG, Jimenez SA, Weaver EJ, Maguire JI, Tasman W, Prockop DJ. Stop codon in the procollagen II gene (COL2A1) in a family with the Stickler syndrome (arthro-ophthalmopathy). Proceedings of the National Academy of Sciences of the United States of America. 88: 6624-7. PMID 1677770 DOI: 10.1073/Pnas.88.15.6624  0.327
1990 Dombrowski KE, Vogel BE, Prockop DJ. Mutations that alter the primary structure of type I procollagen have long-range effects on its cleavage by procollagen N-proteinase. Biochemistry. 28: 7107-12. PMID 2684272 DOI: 10.1021/Bi00443A048  0.309
1990 Hulmes DJ, Kadler KE, Mould AP, Hojima Y, Holmes DF, Cummings C, Chapman JA, Prockop DJ. Pleomorphism in type I collagen fibrils produced by persistence of the procollagen N-propeptide. Journal of Molecular Biology. 210: 337-45. PMID 2600969 DOI: 10.1016/0022-2836(89)90335-5  0.3
1990 Prockop DJ, Baldwin CT, Constantinou CD. Mutations in type I procollagen genes that cause osteogenesis imperfecta. Advances in Human Genetics. 19: 105-32. PMID 2193488 DOI: 10.1007/978-1-4757-9065-8_2  0.323
1990 Tryggvason K, Soininen R, Hostikka SL, Ganguly A, Huotari M, Prockop DJ. Structure of the human type IV collagen genes. Annals of the New York Academy of Sciences. 580: 97-111. PMID 2186699 DOI: 10.1111/J.1749-6632.1990.Tb17922.X  0.314
1990 Ala-Kokko L, Prockop DJ. Completion of the intron-exon structure of the gene for human type II procollagen (COL2A1): Variations in the nucleotide sequences of the alleles from three chromosomes Genomics. 8: 454-460. PMID 1981048 DOI: 10.1016/0888-7543(90)90031-O  0.31
1990 Ala-Kokko L, Baldwin CT, Moskowitz RW, Prockop DJ. Single base mutation in the type II procollagen gene (COL2A1) as a cause of primary osteoarthritis associated with a mild chondrodysplasia. Proceedings of the National Academy of Sciences of the United States of America. 87: 6565-8. PMID 1975693 DOI: 10.1073/Pnas.87.17.6565  0.317
1989 Constantinou CD, Nielsen KB, Prockop DJ. A lethal variant of osteogenesis imperfecta has a single base mutation that substitutes cysteine for glycine 904 of the alpha 1(I) chain of type I procollagen. The asymptomatic mother has an unidentified mutation producing an overmodified and unstable type I procollagen. Journal of Clinical Investigation. 83: 574-584. PMID 2913053 DOI: 10.1172/Jci113920  0.313
1989 Ala-Kokko L, Kontusaari S, Baldwin CT, Kuivaniemi H, Prockop DJ. Structure of cDNA clones coding for the entire prepro alpha 1 (III) chain of human type III procollagen. Differences in protein structure from type I procollagen and conservation of codon preferences. The Biochemical Journal. 260: 509-16. PMID 2764886 DOI: 10.1042/Bj2600509  0.322
1989 Prockop DJ, Constantinou CD, Dombrowski KE, Hojima Y, Kadler KE, Kuivaniemi H, Tromp G, Vogel BE. Type I procollagen: The gene-protein system that harbors most of the mutations causing osteogenesis imperfecta and probably more common heritable disorders of connective tissue American Journal of Medical Genetics. 34: 60-67. PMID 2683782 DOI: 10.1002/Ajmg.1320340112  0.328
1989 Pihlajaniemi T, McKeon J, Gay S, Gay R, de Wet WJ, Myers JC, Prockop DJ. Increased expression of the gene for the pro alpha 1(IV) chain of basement-membrane procollagen in cultured skin fibroblasts from two variants of osteogenesis imperfecta. The Biochemical Journal. 257: 439-45. PMID 2649075 DOI: 10.1042/Bj2570439  0.322
1988 Kuivaniemi H, Tromp G, Chu ML, Prockop DJ. Structure of a full-length cDNA clone for the prepro alpha 2(I) chain of human type I procollagen. Comparison with the chicken gene confirms unusual patterns of gene conservation. The Biochemical Journal. 252: 633-40. PMID 3421913 DOI: 10.1042/Bj2520633  0.313
1988 Tromp G, Prockop DJ. Single base mutation in the pro alpha 2(I) collagen gene that causes efficient splicing of RNA from exon 27 to exon 29 and synthesis of a shortened but in-frame pro alpha 2(I) chain Proceedings of the National Academy of Sciences of the United States of America. 85: 5254-5258. PMID 2839839 DOI: 10.1073/Pnas.85.14.5254  0.3
1988 Tikka L, Pihlajaniemi T, Henttu P, Prockop DJ, Tryggvason K. Gene structure for the alpha 1 chain of a human short-chain collagen (type XIII) with alternatively spliced transcripts and translation termination codon at the 5' end of the last exon. Proceedings of the National Academy of Sciences of the United States of America. 85: 7491-5. PMID 2459707 DOI: 10.1073/Pnas.85.20.7491  0.329
1987 Olsen AS, Prockop DJ. Relative transcription rates and mRNA levels for the two chains of type I procollagen. Methods in Enzymology. 144: 74-83. PMID 3626883 DOI: 10.1016/0076-6879(87)44173-6  0.317
1987 Pihlajaniemi T, Myllylä R, Seyer J, Kurkinen M, Prockop DJ. Partial characterization of a low molecular weight human collagen that undergoes alternative splicing. Proceedings of the National Academy of Sciences of the United States of America. 84: 940-4. PMID 3547403 DOI: 10.1073/Pnas.84.4.940  0.327
1987 Constantinou CD, Vogel BE, Jeffrey JJ, Prockop DJ. The A and B fragments of normal type I procollagen have a similar thermal stability to proteinase digestion but are selectively destabilized by structural mutations. European Journal of Biochemistry. 163: 247-51. PMID 3545829 DOI: 10.1111/J.1432-1033.1987.Tb10794.X  0.316
1986 Soininen R, Chow L, Kurkinen M, Tryggvason K, Prockop D. The gene for the alpha 1(IV) chain of human type IV procollagen: the exon structures do not coincide with the two structural subdomains in the globular carboxy-terminus of the protein. The Embo Journal. 5: 2821-2823. DOI: 10.1002/J.1460-2075.1986.Tb04574.X  0.322
1985 Prockop DJ. Mutations in collagen genes. Consequences for rare and common diseases Journal of Clinical Investigation. 75: 783-787. PMID 3884665 DOI: 10.1172/Jci111773  0.303
1985 Prockop DJ, Chu De Wet MLW. Mutations in osteogenesis imperfecta leading to the synthesis of abnormal type I procollagens Annals of the New York Academy of Sciences. 289-297. PMID 3868953 DOI: 10.1111/J.1749-6632.1985.Tb51176.X  0.34
1985 Oikarinen H, Oikarinen AI, Tan EM, Abergel RP, Meeker CA, Chu ML, Prockop DJ, Uitto J. Modulation of procollagen gene expression by retinoids. Inhibition of collagen production by retinoic acid accompanied by reduced type I procollagen messenger ribonucleic acid levels in human skin fibroblast cultures. The Journal of Clinical Investigation. 75: 1545-53. PMID 2987306 DOI: 10.1172/Jci111859  0.328
1985 WET W, SIPPOLA M, BERNARD M, PROCKOP D, CHU M, RAMIREZ F. Electronmicroscopic Localization of Deletions in the Human Pro-?2(I) Collagen Gene Annals of the New York Academy of Sciences. 460: 415-418. DOI: 10.1111/J.1749-6632.1985.Tb51196.X  0.303
1984 Hoffmann HP, Schwartz NB, Rodén L, Prockop DJ. Location of xylosyltransferase in the cisternae of the rough endoplasmic reticulum of embryonic cartilage cells Connective Tissue Research. 12: 151-163. PMID 6426856 DOI: 10.3109/03008208408992780  0.315
1983 Chu ML, Williams CJ, Pepe G, Hirsch JL, Prockop DJ, Ramirez F. Internal deletion in a collagen gene in a perinatal lethal form of osteogenesis imperfecta. Nature. 304: 78-80. PMID 6191221 DOI: 10.1038/304078A0  0.337
1982 Njieha FK, Morikawa T, Tuderman L, Prockop DJ. Partial purification of a procollagen C-proteinase. Inhibition by synthetic peptides and sequential cleavage of type I procollagen. Biochemistry. 21: 757-64. PMID 7041964 DOI: 10.1021/Bi00533A028  0.302
1982 Kimura T, Prockop DJ. Hydroxylation of prolyl residues in type II procollagen in vitro and in cellulo. Lack of preferential hydroxylation of specific regions of the protein Biochemistry. 21: 5482-5488. PMID 6293542 DOI: 10.1021/Bi00265A016  0.329
1982 Guzman NA, Oronsky AL, Suarez G, Meyerson LR, Cutroneo KR, Olsen BR, Prockop DJ. Prolyl 4-Hydroxylase from Human Placenta. Simultaneous Isolation of Immunoglobulin G which Binds to Ascaris Cuticle Collagen Collagen and Related Research. 2: 365-380. DOI: 10.1016/S0174-173X(82)80001-0  0.449
1981 Prockop DJ. Recombinant DNA and collagen research. Is amino acid sequencing obsolete? Can we study diseases involving collagen by analysis of the genes? Collagen and Related Research. 1: 129-135. PMID 7346217 DOI: 10.1016/S0174-173X(80)80012-4  0.32
1981 Uitto VJ, Uitto J, Prockop DJ. Synthesis of type I procollagen: Formation of interchain disulfide bonds before complete hydroxylation of the protein Archives of Biochemistry and Biophysics. 210: 445-454. PMID 7305337 DOI: 10.1016/0003-9861(81)90208-3  0.342
1981 Graves PN, Olsen BR, Fietzek PP, Prockop DJ, Monson JM. Comparison of the NH2-Terminal sequences of chick Type I preprocollagen chains synthesized in an nRNA-dependent reticulocyte lysate. European Journal of Biochemistry. 118: 363-9. PMID 6269854 DOI: 10.1111/J.1432-1033.1981.Tb06411.X  0.449
1981 Myers JC, Chu ML, Faro SH, Clark WJ, Prockop DJ, Ramirez F. Cloning a cDNA for the pro-α2 chain of human type I collagen Proceedings of the National Academy of Sciences of the United States of America. 78: 3516-3520. PMID 6267597 DOI: 10.1073/Pnas.78.6.3516  0.304
1980 Bächinger HP, Bruckner P, Timpl R, Prockop DJ, Engel J. Folding mechanism of the triple helix in type-III collagen and type-III pN-collagen. Role of disulfide bridges and peptide bond isomerization. European Journal of Biochemistry. 106: 619-32. PMID 7398630 DOI: 10.1111/J.1432-1033.1980.Tb04610.X  0.304
1980 Peltonen L, Palotie A, Prockop DJ. A defect in the structure of type I procollagen in a patient who had osteogenesis imperfecta: Excess mannose in the COOH-terminal propeptide Proceedings of the National Academy of Sciences of the United States of America. 77: 6179-6183. PMID 6934545 DOI: 10.1073/Pnas.77.10.6179  0.313
1980 Peltonen L, Palotie A, Hayashi T, Prockop DJ. Thermal stability of type I and type III procollagens from normal human fibroblasts and from a patient with osteogenesis imperfecta. Proceedings of the National Academy of Sciences of the United States of America. 77: 162-6. PMID 6928611 DOI: 10.1073/Pnas.77.1.162  0.301
1978 Uitto VJ, Uitto J, Kao WW, Prockop DJ. Procollagen polypeptides containing cis-4-hydroxy-L-proline are overglycosylated and secreted as nonhelical pro-gamma-chains. Archives of Biochemistry and Biophysics. 185: 214-21. PMID 623484 DOI: 10.1016/0003-9861(78)90161-3  0.323
1978 Guzman NA, Graves PN, Prockop DJ. Addition of mannose to both the amino- and carboxy-terminal properties of type II procollagen occurs without formation of a triple helix. Biochemical and Biophysical Research Communications. 84: 691-8. PMID 568927 DOI: 10.1016/0006-291X(78)90760-X  0.343
1977 Prockop DJ, Guzman NA. Collagen diseases and the biosynthesis of collagen Hospital Practice. 12: 61-68. PMID 924426 DOI: 10.1080/21548331.1977.11707242  0.305
1977 Bressan GM, Prockop DJ. Is newly-secreted elastin cleaved to a smaller molecule before being incorporated into crosslinked elastin fibers? Advances in Experimental Medicine and Biology. 79: 443-451. PMID 868653 DOI: 10.1007/978-1-4684-9093-0_38  0.314
1977 Kao WWY, Prockop DJ. Proline analogue removes fibroblasts from cultured mixed cell populations [19] Nature. 266: 63-64. PMID 758007 DOI: 10.1038/266063A0  0.332
1977 Uitto J, Hoffmann HP, Prockop DJ. Purification and partial characterization of the type II procollagen synthesized by embryonic cartilage cells Archives of Biochemistry and Biophysics. 179: 654-662. PMID 557959 DOI: 10.1016/0003-9861(77)90154-0  0.333
1977 Bressan GM, Prockop DJ. Synthesis of elastin in aortas from chick embryos. Conversion of newly secreted elastin to cross-linked elastin without apparent proteolysis of the molecule Biochemistry. 16: 1406-1412. PMID 557339 DOI: 10.1021/Bi00626A026  0.317
1976 Hoffmann HP, Olsen BR, Chen HT, Prockop DJ. Segment long spacing aggregates and isolation of COOH terminal peptides from type I procollagen Proceedings of the National Academy of Sciences of the United States of America. 73: 4304-4308. PMID 1069985 DOI: 10.1073/Pnas.73.12.4304  0.477
1976 Olsen BR, Hoffmann HP, Prockop DJ. Interchain disulfide bonds at the COOH-terminal end of procollagen synthesized by matrix-free cells from chick embryonic tendon and cartilage Archives of Biochemistry and Biophysics. 175: 341-350. PMID 182083 DOI: 10.1016/0003-9861(76)90516-6  0.483
1976 Uitto J, Hoffmann HP, Prockop DJ. Synthesis of elastin and procollagen by cells from embryonic aorta. Differences in the role of hydroxyproline and the effects of proline analogs on the secretion of the two proteins Archives of Biochemistry and Biophysics. 173: 187-200. PMID 176945 DOI: 10.1016/0003-9861(76)90249-6  0.339
1976 Kao WW, Berg RA, Prockop DJ. Ascorbate increases the synthesis of procollagen hydroxyproline by cultured fibroblasts from chick embryo tendons without activation of prolyl hydroxyla. Biochimica Et Biophysica Acta. 411: 202-15. PMID 172137 DOI: 10.1016/0304-4165(75)90300-1  0.312
1976 Berg RA, Kao WW, Prockop DJ. Prolyl hydroxylase activity in L-929 fibroblasts incubated with and without ascorbate Biochimica Et Biophysica Acta (Bba) - General Subjects. 444: 756-764. DOI: 10.1016/0304-4165(76)90322-6  0.312
1975 Kishida Y, Olsen BR, Berg RA, Prockop DJ. Two improved methods for preparing ferritin protein conjugates for electron microscopy Journal of Cell Biology. 64: 331-339. PMID 803973 DOI: 10.1083/Jcb.64.2.331  0.436
1975 Olsen BR, Berg RA, Kishida Y, Prockop DJ. Further characterization of embryonic tendon fibroblasts and the use of immunoferritin techniques to study collagen biosynthesis Journal of Cell Biology. 64: 340-355. PMID 163830 DOI: 10.1083/Jcb.64.2.340  0.51
1974 Kivirikko KI, Ryhänen L, Anttinen H, Bornstein P, Prockop DJ. Further hydroxylation of lysyl residues in collagen by protocollagen lysyl hydroxylase in vitro. Biochemistry. 12: 4966-71. PMID 4761977 DOI: 10.1021/Bi00748A023  0.317
1974 Olsen BR, Prockop DJ. Ferritin conjugated antibodies used for labeling of organelles involved in the cellular synthesis and transport of procollagen Proceedings of the National Academy of Sciences of the United States of America. 71: 2033-2037. PMID 4525314 DOI: 10.1073/Pnas.71.5.2033  0.456
1974 Uitto J, Prockop DJ. Hydroxylation of peptide-bound proline and lysine before and after chain completion of the polypeptide chains of procollagen Archives of Biochemistry and Biophysics. 164: 210-217. PMID 4473958 DOI: 10.1016/0003-9861(74)90024-1  0.301
1974 Uitto J, Prockop DJ. Synthesis and secretion of under-hydroxylated procollagen at various temperatures by cells subject to temporary anoxia Biochemical and Biophysical Research Communications. 60: 414-423. PMID 4472803 DOI: 10.1016/0006-291X(74)90220-4  0.334
1974 Uitto J, Prockop DJ. Biosynthesis of cartilage procollagen. Influence of chain association and hydroxylation of prolyl residues on the folding of the polypeptides into the triple-helical conformation Biochemistry. 13: 4586-4591. PMID 4371812 DOI: 10.1021/Bi00719A018  0.335
1974 Uitto J, Prockop DJ. Intracellular hydroxylation of non helical protocollagen to form triple helical procollagen and subsequent secretion of the molecule European Journal of Biochemistry. 43: 221-230. PMID 4365178 DOI: 10.1111/J.1432-1033.1974.Tb03403.X  0.326
1974 Dehm P, Olsen BR, Prockop DJ. Antibodies to chick tendon procollagen. Affinity purification with the isolated disulfide linked NH2 terminal extensions and reactivity with a component in embryonic serum European Journal of Biochemistry. 46: 107-116. PMID 4136533 DOI: 10.1111/J.1432-1033.1974.Tb03602.X  0.455
1974 SCHOFIELD JD, UITTO JJ, PROCKOP DJ. Interchain Disulphide Bonding in Procollagen from Embryonic Chick Tendon Cells and the Formation of the Triple-Helical Structure Biochemical Society Transactions. 2: 90-93. DOI: 10.1042/Bst0020090  0.312
1974 Uitto J, Prockop DJ. Incorporation of proline analogues into collagen polypeptides Effects on the production of extracellular procollagen and on the stability of the triple-helical structure of the molecule Bba - Protein Structure. 336: 234-251. DOI: 10.1016/0005-2795(74)90401-2  0.315
1973 Berg RA, Prockop DJ. The thermal transition of a non-hydroxylated form of collagen. Evidence for a role for hydroxyproline in stabilizing the triple-helix of collagen Biochemical and Biophysical Research Communications. 52: 115-120. PMID 4712181 DOI: 10.1016/0006-291X(73)90961-3  0.303
1973 Uitto J, Prockop DJ. Rate of helix formation by intracellular procollagen and protocollagen. Evidence for a role for disulfide bons Biochemical and Biophysical Research Communications. 55: 904-911. PMID 4586622 DOI: 10.1016/0006-291X(73)91229-1  0.334
1973 Olsen BR, Berg RA, Kishida Y, Prockop DJ. Collagen synthesis: Localization of prolyl hydroxylase in tendon cells detected with ferritin labeled antibodies Science. 182: 825-827. PMID 4355681 DOI: 10.1126/Science.182.4114.825  0.472
1973 Dehm P, Prockop DJ. Biosynthesis of cartilage procollagen. European Journal of Biochemistry. 35: 159-66. PMID 4351528 DOI: 10.1111/J.1432-1033.1973.Tb02821.X  0.371
1973 Olsen BR, Berg RA, Kivirikko KI, Prockop DJ. Structure of Protocollagen Proline Hydroxylase from Chick Embryos European Journal of Biochemistry. 35: 135-147. PMID 4351527 DOI: 10.1111/J.1432-1033.1973.Tb02819.X  0.427
1972 Prockop DJ. A subtle disease and a dilemma: can cells secrete collagen that does not contain a sugar-tag? New England Journal of Medicine. 286: 1055-1056. PMID 5016374 DOI: 10.1056/Nejm197205112861910  0.303
1972 Uitto J, Jimenez SA, Dehm P, Prockop DJ. Characterization of the precursor forms of the α1 and α2 chains of collagen from matrix-free tendon cells Bba - Protein Structure. 278: 198-205. PMID 4672181 DOI: 10.1016/0005-2795(72)90123-7  0.305
1972 Uitto J, Dehm P, Prockop DJ. Incorporation of cis-hydroxyproline into collagen by tendon cells. Failure of the intracellular collagen to assume a triple-helical conformation Bba - Protein Structure. 278: 601-605. PMID 4563773 DOI: 10.1016/0005-2795(72)90023-2  0.332
1972 Dehm P, Prockop DJ. Time lag in the secretion of collagen by matrix-free tendon cells and inhibition of the secretory process by colchicine and vinblastine Bba - General Subjects. 264: 375-382. PMID 4337621 DOI: 10.1016/0304-4165(72)90302-9  0.316
1972 Dehm P, Jimenez SA, Olsen BR, Prockop DJ. A transport form of collagen from embryonic tendon: electron microscopic demonstration of an NH 2 -terminal extension and evidence suggesting the presence of cystine in the molecule (chick embryo-tropocollagen-gel filtration) Proceedings of the National Academy of Sciences of the United States of America. 69: 60-64. PMID 4333046 DOI: 10.1073/Pnas.69.1.60  0.464
1972 Grant ME, Prockop DJ. The biosynthesis of collagen. 1 New England Journal of Medicine. 286: 194-199. PMID 4257078 DOI: 10.1056/Nejm197201272860406  0.301
1972 Berg RA, Olsen BR, Prockop DJ. Labeled antibodies to protocollagen proline hydroxylase from chick embryos for intracellular localization of the enzyme Bba - Protein Structure. 285: 167-175. PMID 4120059 DOI: 10.1016/0005-2795(72)90188-2  0.434
1971 Lane JM, Dehm P, Prockop DJ. Effect of the proline analogue azetidine-2-carboxylic acid on collagen synthesis in vivo I. Arrest of collagen accumulation in growing chick embryos Bba - Protein Structure. 236: 517-527. PMID 5559959 DOI: 10.1016/0005-2795(71)90235-2  0.33
1971 Lane J, Rosenbloom J, Prockop DJ. Lag between incorporation of proline into protocollagen and synthesis of hydroxyproline during collagen biosynthesis in vitro and in vivo Nature: New Biology. 232: 191-192. PMID 5285273 DOI: 10.1038/Newbio232191A0  0.313
1971 Olsen BR, Berg RA, Sakakibara S, Kishida Y, Prockop DJ. The synthetic polytripeptides (Pro-Pro-Gly)10 and (Pro-Pro-Gly)20 form micro-crystalline structures similar to segmental structures formed by collagen. Journal of Molecular Biology. 57: 589-95. PMID 4103752 DOI: 10.1016/0022-2836(71)90111-2  0.451
1971 Dehm P, Prockop DJ. Synthesis and extrusion of collagen by freshly isolated cells from chick embryo tendon Bba Section Nucleic Acids and Protein Synthesis. 240: 358-369. DOI: 10.1016/0005-2787(71)90529-6  0.368
1969 Takeuchi T, Rosenbloom J, Prockop DJ. Biosynthesis of abnormal collagens with amino acid analogues. II. Inability of cartilage cells to extrude collagen polypeptides containing l-azetidine-2-carboxylic acid or cis-4-fluoro-l-proline Bba - Protein Structure. 175: 156-164. PMID 5765999 DOI: 10.1016/0005-2795(69)90154-8  0.302
1969 Prockop DJ. The Intracellular Biosynthesis of Collagen: Some Possible Implications for Diseases of Bone and Other Connective Tissues Archives of Internal Medicine. 124: 563-570. PMID 5345862 DOI: 10.1001/Archinte.124.5.563  0.317
1968 Cooper GW, Prockop DJ. Intracellular accumulation of protocollagen and extrusion of collagen by embryonic cartilage cells Journal of Cell Biology. 38: 523-537. PMID 5664222 DOI: 10.1083/Jcb.38.3.523  0.3
1967 Kivirikko KI, Prockop DJ. Partial characterization of protocollagen from embryonic cartilage Biochemical Journal. 102: 432-442. PMID 6029602 DOI: 10.1042/Bj1020432  0.339
1967 Rosenbloom J, Bhatnagar RS, Prockop DJ. Hydroxylation of proline after the release of proline-rich polypeptides from ribosomal complexes during uninhibited collagen biosynthesis Bba Section Nucleic Acids and Protein Synthesis. 149: 259-272. PMID 5582744 DOI: 10.1016/0005-2787(67)90707-1  0.3
1966 Prockop DJ, Weinstein E, Mulveny T. Hydroxylation of lysine in a polypeptide precursor of collagen Biochemical and Biophysical Research Communications. 22: 124-128. PMID 5937328 DOI: 10.1016/0006-291X(66)90613-9  0.328
1966 Juva K, Prockop DJ, Cooper GW, Lash JW. Hydroxylation of proline and the intracellular accumulation of a polypeptide precursor of collagen. Science (New York, N.Y.). 152: 92-4. PMID 5910019 DOI: 10.1126/Science.152.3718.92  0.302
1966 Bhatnagar RS, Prockop DJ. Dissociation of the synthesis of sulphated mucopolysaccharides and the synthesis of collagen in embryonic cartilage Bba - General Subjects. 130: 383-392. PMID 4226472 DOI: 10.1016/0304-4165(66)90234-0  0.302
1964 PROCKOP DJ, PETTENGILL O, HOLTZER H. INCORPORATION OF SULFATE AND THE SYNTHESIS OF COLLAGEN BY CULTURES OF EMBRYONIC CHONDROCYTES. Biochimica Et Biophysica Acta. 83: 189-96. PMID 14200684 DOI: 10.1016/0926-6526(64)90034-5  0.317
1963 PROCKOP D, KAPLAN A, UDENFRIEND S. Oxygen-18 studies on the conversion of proline to collagen hydroxyproline. Archives of Biochemistry and Biophysics. 101: 499-503. PMID 13986293 DOI: 10.1016/0003-9861(63)90509-5  0.58
1962 PROCKOP D, KAPLAN A, UDENFRIEND S. Oxygen-18 studies on the conversion of proline to hydroxyproline. Biochemical and Biophysical Research Communications. 9: 162-6. PMID 13986292 DOI: 10.1016/0006-291X(62)90107-9  0.558
1961 PROCKOP DJ, UDENFRIEND S, LINDSTEDT S. A simple technique for measuring the specific activity of labeled hydroxyproline in biological materials. The Journal of Biological Chemistry. 236: 1395-8. PMID 13738133  0.346
1961 PROCKOP DJ, SJOERDSMA A. Significance of urinary hydroxyproline in man The Journal of Clinical Investigation. 40: 843-849. PMID 13738132 DOI: 10.1172/Jci104318  0.466
1960 Prockop DJ, Udenfriend S. A specific method for the analysis of hydroxyproline in tissues and urine Analytical Biochemistry. 1: 228-239. PMID 13738134 DOI: 10.1016/0003-2697(60)90050-6  0.447
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