Ian M. Willis - Publications

Affiliations: 
Yeshiva University, New York, NY, United States 
Area:
Biochemistry

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Moir RD, Lavados C, Lee J, Willis IM. Functional characterization of Polr3a hypomyelinating leukodystrophy mutations in the S. cerevisiae homolog, RPC160. Gene. 145259. PMID 33148458 DOI: 10.1016/j.gene.2020.145259  0.56
2020 Bonhoure N, Praz V, Moir RD, Willemin G, Mange F, Moret C, Willis IM, Hernandez N. MAF1 is a chronic repressor of RNA polymerase III transcription in the mouse. Scientific Reports. 10: 11956. PMID 32686713 DOI: 10.1038/s41598-020-68665-0  0.56
2020 Vorländer MK, Baudin F, Moir RD, Wetzel R, Hagen WJH, Willis IM, Müller CW. Structural basis for RNA polymerase III transcription repression by Maf1. Nature Structural & Molecular Biology. PMID 32066962 DOI: 10.1038/s41594-020-0383-y  0.56
2019 Choquet K, Pinard M, Yang S, Moir RD, Poitras C, Dicaire MJ, Sgarioto N, Larivière R, Kleinman CL, Willis IM, Gauthier MS, Coulombe B, Brais B. The leukodystrophy mutation Polr3b R103H causes homozygote mouse embryonic lethality and impairs RNA polymerase III biogenesis. Molecular Brain. 12: 59. PMID 31221184 DOI: 10.1186/s13041-019-0479-7  0.56
2018 Willis IM, Moir RD, Hernandez N. Metabolic programming a lean phenotype by deregulation of RNA polymerase III. Proceedings of the National Academy of Sciences of the United States of America. PMID 30429315 DOI: 10.1073/pnas.1815590115  0.56
2018 Qiu Y, Moir RD, Willis IM, Seethapathy S, Biniakewitz RC, Kurland IJ. Enhanced Isotopic Ratio Outlier Analysis (IROA) Peak Detection and Identification with Ultra-High Resolution GC-Orbitrap/MS: Potential Application for Investigation of Model Organism Metabolomes. Metabolites. 8. PMID 29346327 DOI: 10.3390/metabo8010009  0.56
2018 Willis IM, Moir RD. Signaling to and from the RNA Polymerase III Transcription and Processing Machinery. Annual Review of Biochemistry. PMID 29328783 DOI: 10.1146/annurev-biochem-062917-012624  0.56
2017 Choquet K, Yang S, Moir RD, Forget D, Larivière R, Bouchard A, Poitras C, Sgarioto N, Dicaire MJ, Noohi F, Kennedy TE, Rochford J, Bernard G, Teichmann M, Coulombe B, ... Willis IM, et al. Absence of neurological abnormalities in mice homozygous for the Polr3a G672E hypomyelinating leukodystrophy mutation. Molecular Brain. 10: 13. PMID 28407788 DOI: 10.1186/s13041-017-0294-y  0.56
2016 Dasgupta S, Yang C, Castro LM, Tashima AK, Ferro ES, Moir RD, Willis IM, Fricker LD. Analysis of the Yeast Peptidome and Comparison with the Human Peptidome. Plos One. 11: e0163312. PMID 27685651 DOI: 10.1371/journal.pone.0163312  0.56
2016 Qiu Y, Moir R, Willis IM, Beecher C, Tsai YH, Garrett TJ, Yost RA, Kurland IJ. Isotopic Ratio Outlier Analysis (IROA) of the S. cerevisiae metabolome using accurate mass GC-TOF/MS: A new method for discovery. Analytical Chemistry. PMID 26820234 DOI: 10.1021/acs.analchem.5b04263  0.56
2015 Lee J, Moir RD, Willis IM. Differential Phosphorylation of RNA Polymerase III and the Initiation Factor TFIIIB in Saccharomyces cerevisiae. Plos One. 10: e0127225. PMID 25970584 DOI: 10.1371/journal.pone.0127225  0.56
2015 Bonhoure N, Byrnes A, Moir RD, Hodroj W, Preitner F, Praz V, Marcelin G, Chua SC, Martinez-Lopez N, Singh R, Moullan N, Auwerx J, Willemin G, Shah H, Hartil K, ... ... Willis IM, et al. Loss of the RNA polymerase III repressor MAF1 confers obesity resistance. Genes & Development. 29: 934-47. PMID 25934505 DOI: 10.1101/gad.258350.115  0.56
2015 Sanchez-Casalongue ME, Lee J, Diamond A, Shuldiner S, Moir RD, Willis IM. Differential phosphorylation of a regulatory subunit of protein kinase CK2 by target of rapamycin complex 1 signaling and the Cdc-like kinase Kns1. The Journal of Biological Chemistry. 290: 7221-33. PMID 25631054 DOI: 10.1074/jbc.M114.626523  0.56
2015 Frame IJ, Deniskin R, Rinderspacher A, Katz F, Deng SX, Moir RD, Adjalley SH, Coburn-Flynn O, Fidock DA, Willis IM, Landry DW, Akabas MH. Yeast-based high-throughput screen identifies Plasmodium falciparum equilibrative nucleoside transporter 1 inhibitors that kill malaria parasites. Acs Chemical Biology. 10: 775-83. PMID 25602169 DOI: 10.1021/cb500981y  0.56
2015 Moir RD, Willis IM. Regulating maf1 expression and its expanding biological functions. Plos Genetics. 11: e1004896. PMID 25568945 DOI: 10.1371/journal.pgen.1004896  0.56
2014 Bonhoure N, Bounova G, Bernasconi D, Praz V, Lammers F, Canella D, Willis IM, Herr W, Hernandez N, Delorenzi M, Deplancke B, Desvergne B, Guex N, Naef F, Rougemont J, et al. Quantifying ChIP-seq data: A spiking method providing an internal reference for sample-to-sample normalization Genome Research. 24: 1157-1168. PMID 24709819 DOI: 10.1101/gr.168260.113  0.56
2014 Atencio D, Barnes C, Duncan TM, Willis IM, Hanes SD. The yeast Ess1 prolyl isomerase controls Swi6 and Whi5 nuclear localization. G3 (Bethesda, Md.). 4: 523-37. PMID 24470217 DOI: 10.1534/g3.113.008763  0.56
2013 Moir RD, Willis IM. Regulation of pol III transcription by nutrient and stress signaling pathways. Biochimica Et Biophysica Acta. 1829: 361-75. PMID 23165150 DOI: 10.1016/j.bbagrm.2012.11.001  0.56
2012 Nika H, Lee J, Willis IM, Angeletti RH, Hawke DH. Phosphopeptide characterization by mass spectrometry using reversed-phase supports for solid-phase β-elimination/Michael addition. Journal of Biomolecular Techniques : Jbt. 23: 51-68. PMID 22951960 DOI: 10.7171/jbt.2012-2302-002  0.56
2012 Moir RD, Gross DA, Silver DL, Willis IM. SCS3 and YFT2 link transcription of phospholipid biosynthetic genes to ER stress and the UPR. Plos Genetics. 8: e1002890. PMID 22927826 DOI: 10.1371/journal.pgen.1002890  0.56
2012 Moir RD, Lee J, Willis IM. Recovery of RNA polymerase III transcription from the glycerol-repressed state: revisiting the role of protein kinase CK2 in Maf1 phosphoregulation. The Journal of Biological Chemistry. 287: 30833-41. PMID 22810236 DOI: 10.1074/jbc.M112.378828  0.56
2012 Short MK, Hallett JP, Tar K, Dange T, Schmidt M, Moir R, Willis IM, Jubinsky PT. The yeast magmas ortholog pam16 has an essential function in fermentative growth that involves sphingolipid metabolism. Plos One. 7: e39428. PMID 22808036 DOI: 10.1371/journal.pone.0039428  0.56
2012 Willis IM, Lee J. Two new kinases in the TOR signaling network regulate ribosome and tRNA synthesis. Cell Cycle (Georgetown, Tex.). 11: 2769-70. PMID 22801535 DOI: 10.4161/cc.21257  0.56
2012 Lee J, Moir RD, McIntosh KB, Willis IM. TOR signaling regulates ribosome and tRNA synthesis via LAMMER/Clk and GSK-3 family kinases. Molecular Cell. 45: 836-43. PMID 22364741 DOI: 10.1016/j.molcel.2012.01.018  0.56
2012 Lajoie P, Moir RD, Willis IM, Snapp EL. Kar2p availability defines distinct forms of endoplasmic reticulum stress in living cells. Molecular Biology of the Cell. 23: 955-64. PMID 22219379 DOI: 10.1091/mbc.E11-12-0995  0.56
2011 McIntosh KB, Bhattacharya A, Willis IM, Warner JR. Eukaryotic cells producing ribosomes deficient in Rpl1 are hypersensitive to defects in the ubiquitin-proteasome system. Plos One. 6: e23579. PMID 21858174 DOI: 10.1371/journal.pone.0023579  0.56
2011 Willis IM, Moir RD, Lee J. Does casein kinase II phosphorylation of Maf1 trigger RNA polymerase III activation? Proceedings of the National Academy of Sciences of the United States of America. 108: E300; author reply E. PMID 21734148 DOI: 10.1073/pnas.1107306108  0.56
2011 Rana T, Misra S, Mittal MK, Farrow AL, Wilson KT, Linton MF, Fazio S, Willis IM, Chaudhuri G. Mechanism of down-regulation of RNA polymerase III-transcribed non-coding RNA genes in macrophages by Leishmania. The Journal of Biological Chemistry. 286: 6614-26. PMID 21149457 DOI: 10.1074/jbc.M110.181735  0.56
2010 Bhattacharya A, McIntosh KB, Willis IM, Warner JR. Why Dom34 stimulates growth of cells with defects of 40S ribosomal subunit biosynthesis. Molecular and Cellular Biology. 30: 5562-71. PMID 20876302 DOI: 10.1128/MCB.00618-10  0.56
2009 Lee J, Moir RD, Willis IM. Regulation of RNA polymerase III transcription involves SCH9-dependent and SCH9-independent branches of the target of rapamycin (TOR) pathway. The Journal of Biological Chemistry. 284: 12604-8. PMID 19299514 DOI: 10.1074/jbc.C900020200  0.56
2009 Rosonina E, Willis IM, Manley JL. Sub1 functions in osmoregulation and in transcription by both RNA polymerases II and III. Molecular and Cellular Biology. 29: 2308-21. PMID 19204085 DOI: 10.1128/MCB.01841-08  0.56
2008 Cabart P, Lee J, Willis IM. Facilitated recycling protects human RNA polymerase III from repression by Maf1 in vitro. The Journal of Biological Chemistry. 283: 36108-17. PMID 18974046 DOI: 10.1074/jbc.M807538200  0.56
2008 Willis IM, Chua G, Tong AH, Brost RL, Hughes TR, Boone C, Moir RD. Genetic interactions of MAF1 identify a role for Med20 in transcriptional repression of ribosomal protein genes. Plos Genetics. 4: e1000112. PMID 18604275 DOI: 10.1371/journal.pgen.1000112  0.56
2007 Caplan AJ, Ma'ayan A, Willis IM. Multiple kinases and system robustness: a link between Cdc37 and genome integrity. Cell Cycle (Georgetown, Tex.). 6: 3145-7. PMID 18075309  0.56
2007 Johnson SS, Zhang C, Fromm J, Willis IM, Johnson DL. Mammalian Maf1 is a negative regulator of transcription by all three nuclear RNA polymerases. Molecular Cell. 26: 367-79. PMID 17499043 DOI: 10.1016/j.molcel.2007.03.021  0.56
2007 Willis IM, Moir RD. Integration of nutritional and stress signaling pathways by Maf1. Trends in Biochemical Sciences. 32: 51-3. PMID 17174096 DOI: 10.1016/j.tibs.2006.12.001  0.56
2006 Moir RD, Lee J, Haeusler RA, Desai N, Engelke DR, Willis IM. Protein kinase A regulates RNA polymerase III transcription through the nuclear localization of Maf1. Proceedings of the National Academy of Sciences of the United States of America. 103: 15044-9. PMID 17005718 DOI: 10.1073/pnas.0607129103  0.56
2006 Liao Y, Moir RD, Willis IM. Interactions of Brf1 peptides with the tetratricopeptide repeat-containing subunit of TFIIIC inhibit and promote preinitiation complex assembly. Molecular and Cellular Biology. 26: 5946-56. PMID 16880507 DOI: 10.1128/MCB.00689-06  0.56
2005 Sauve AA, Moir RD, Schramm VL, Willis IM. Chemical activation of Sir2-dependent silencing by relief of nicotinamide inhibition. Molecular Cell. 17: 595-601. PMID 15721262 DOI: 10.1016/j.molcel.2004.12.032  0.56
2005 Desai N, Lee J, Upadhya R, Chu Y, Moir RD, Willis IM. Two steps in Maf1-dependent repression of transcription by RNA polymerase III. The Journal of Biological Chemistry. 280: 6455-62. PMID 15590667 DOI: 10.1074/jbc.M412375200  0.56
2004 Willis IM, Desai N, Upadhya R. Signaling repression of transcription by RNA polymerase III in yeast. Progress in Nucleic Acid Research and Molecular Biology. 77: 323-53. PMID 15196897 DOI: 10.1016/S0079-6603(04)77009-9  0.56
2004 Moir RD, Willis IM. Tetratricopeptide repeats of Tfc4 and a limiting step in the assembly of the initiation factor TFIIIB. Advances in Protein Chemistry. 67: 93-121. PMID 14969725 DOI: 10.1016/S0065-3233(04)67004-5  0.56
2003 Liao Y, Willis IM, Moir RD. The Brf1 and Bdp1 subunits of transcription factor TFIIIB bind to overlapping sites in the tetratricopeptide repeats of Tfc4. The Journal of Biological Chemistry. 278: 44467-74. PMID 12930823 DOI: 10.1074/jbc.M308354200  0.56
2003 Wu L, Pan J, Thoroddsen V, Wysong DR, Blackman RK, Bulawa CE, Gould AE, Ocain TD, Dick LR, Errada P, Dorr PK, Parkinson T, Wood T, Kornitzer D, Weissman Z, ... Willis IM, et al. Novel small-molecule inhibitors of RNA polymerase III. Eukaryotic Cell. 2: 256-64. PMID 12684375 DOI: 10.1128/EC.2.2.256-264.2003  0.56
2002 Upadhya R, Lee J, Willis IM. Maf1 is an essential mediator of diverse signals that repress RNA polymerase III transcription. Molecular Cell. 10: 1489-94. PMID 12504022 DOI: 10.1016/S1097-2765(02)00787-6  0.56
2002 Moir RD, Puglia KV, Willis IM. A gain-of-function mutation in the second tetratricopeptide repeat of TFIIIC131 relieves autoinhibition of Brf1 binding. Molecular and Cellular Biology. 22: 6131-41. PMID 12167707 DOI: 10.1128/MCB.22.17.6131-6141.2002  0.56
2002 Willis IM. A universal nomenclature for subunits of the RNA polymerase III transcription initiation factor TFIIIB. Genes & Development. 16: 1337-8. PMID 12066800 DOI: 10.1101/gad.998102  0.56
2002 Moir RD, Puglia KV, Willis IM. Autoinhibition of TFIIIB70 binding by the tetratricopeptide repeat-containing subunit of TFIIIC. The Journal of Biological Chemistry. 277: 694-701. PMID 11684692 DOI: 10.1074/jbc.M108924200  0.56
2001 Cloutier TE, Librizzi MD, Mollah AK, Brenowitz M, Willis IM. Kinetic trapping of DNA by transcription factor IIIB. Proceedings of the National Academy of Sciences of the United States of America. 98: 9581-6. PMID 11481428 DOI: 10.1073/pnas.161292298  0.56
2001 Kruppa M, Moir RD, Kolodrubetz D, Willis IM. Nhp6, an HMG1 protein, functions in SNR6 transcription by RNA polymerase III in S. cerevisiae Molecular Cell. 7: 309-318. PMID 11239460 DOI: 10.1016/S1097-2765(01)00179-4  0.56
2000 Moir RD, Puglia KV, Willis IM. Interactions between the tetratricopeptide repeats-containing transcription factor TFIIIC131 and its ligand, TFIIIB70: Evidence for a conformational change in the complex Journal of Biological Chemistry. 275: 26591-26598. PMID 10859316 DOI: 10.1074/jbc.M003991200  0.56
2000 Li Y, Moir RD, Sethy-Coraci IK, Warner JR, Willis IM. Repression of ribosome and tRNA synthesis in secretion-defective cells is signaled by a novel branch of the cell integrity pathway Molecular and Cellular Biology. 20: 3843-3851. PMID 10805727 DOI: 10.1128/MCB.20.11.3843-3851.2000  0.56
1998 Sethy-Coraci I, Moir RD, López-de-León A, Willis IM. A differential response of wild type and mutant promoters to TFIIIB70 overexpression in vivo and in vitro Nucleic Acids Research. 26: 2344-2352. PMID 9580684 DOI: 10.1093/nar/26.10.2344  0.56
1998 Librizzi MD, Brenowitz M, Willis IM. The TATA element and its context affect the cooperative interaction of TATA-binding protein with the TFIIB-related factor, TFIIIB70 Journal of Biological Chemistry. 273: 4563-4568. PMID 9468512 DOI: 10.1074/jbc.273.8.4563  0.56
1997 Moir RD, Sethy-Coraci I, Puglia K, Librizzi MD, Willis IM. A tetratricopeptide repeat mutation in yeast transcription factor IIIC131 (TFIIIC131) facilitates recruitment of TFIIB-related factor TFIIIB70 Molecular and Cellular Biology. 17: 7119-7125. PMID 9372943 DOI: 10.1128/MCB.17.12.7119  0.56
1996 Librizzi MD, Moir RD, Brenowitz M, Willis IM. Expression and purification of the RNA polymerase III transcription specificity factor IIIB70 from Saccharomyces cerevisiae and its cooperative binding with TATA-binding protein Journal of Biological Chemistry. 271: 32695-32701. PMID 8955101  0.56
1995 Sethy I, Moir RD, Librizzi M, Willis IM. In vitro evidence for growth regulation of tRNA gene transcription in yeast: A role for transcription factor (TF) IIIB70 and TFIIIC Journal of Biological Chemistry. 270: 28463-28470. PMID 7499353 DOI: 10.1074/jbc.270.47.28463  0.56
1995 Sethy I, Willis IM. Recessive mutations in the second largest subunit of TFIIIC suggest a new step in RNA polymerase III transcription Gene Expression. 5: 35-47. PMID 7488859  0.56
1994 Pak M, Willis IM, Schulman LH. Analysis of acceptor stem base pairing on tRNA(Trp) aminoacylation and function in vivo. The Journal of Biological Chemistry. 269: 2277-82. PMID 8294486  0.56
1993 Willis IM. RNA polymerase III. Genes, factors and transcriptional specificity European Journal of Biochemistry. 212: 1-11. PMID 8444147  0.56
1993 Werner M, Chaussivert N, Willis IM, Sentenac A. Interaction between a complex of RNA polymerase III subunits and the 70-kDa component of transcription factor IIIB Journal of Biological Chemistry. 268: 20721-20724. PMID 8407894  0.56
1992 López-De-León A, Librizzi M, Puglia K, Willis IM. PCF4 encodes an RNA polymerase III transcription factor with homology to TFIIB Cell. 71: 211-220. PMID 1423589 DOI: 10.1016/0092-8674(92)90350-L  0.56
1989 Alexander LJ, Hayes G, Pearse MJ, Beattie CW, Stewart AF, Willis IM, Mackinlay AG. Complete sequence of the bovine beta-lactoglobulin cDNA. Nucleic Acids Research. 17: 6739. PMID 2701948 DOI: 10.1093/nar/17.16.6739  0.56
1987 Stewart AF, Bonsing J, Beattie CW, Shah F, Willis IM, Mackinlay AG. Complete nucleotide sequences of bovine alpha S2- and beta-casein cDNAs: comparisons with related sequences in other species. Molecular Biology and Evolution. 4: 231-41. PMID 2833669  0.56
1984 Stewart AF, Willis IM, Mackinlay AF. Nucteotide sequences of bovine αS1- and x-casein cDNAs Nucleic Acids Research. 12: 3895-3907. PMID 6328443 DOI: 10.1093/nar/12.9.3895  0.56
1982 Willis IM, Stewart AF, Caputo A, Thompson AR, Mackinlay AG. Construction and identification by partial nucleotide sequence analysis of bovine casein and β-lactoglobulin cDNA clones Dna. 1: 375-386. PMID 6897774  0.56
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