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Kareem A. Chehade, Ph.D. - Publications

Affiliations: 
2001 University of Kentucky, Lexington, KY 
Area:
Biochemistry
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8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Rising KA, Crenshaw CM, Koo HJ, Subramanian T, Chehade KA, Starks C, Allen KD, Andres DA, Spielmann HP, Noel JP, Chappell J. Formation of a Novel Macrocyclic Alkaloid from the Unnatural Farnesyl Diphosphate Analogue Anilinogeranyl Diphosphate by 5-Epi-Aristolochene Synthase. Acs Chemical Biology. 10: 1729-36. PMID 25897591 DOI: 10.1021/Acschembio.5B00145  0.494
2006 Roberts MJ, Troutman JM, Chehade KA, Cha HC, Kao JP, Huang X, Zhan CG, Peterson YK, Subramanian T, Kamalakkannan S, Andres DA, Spielmann HP. Hydrophilic anilinogeranyl diphosphate prenyl analogues are Ras function inhibitors. Biochemistry. 45: 15862-72. PMID 17176109 DOI: 10.1021/BI061704+  0.601
2004 Troutman JM, Chehade KA, Kiegiel K, Andres DA, Spielmann HP. Synthesis of acyloxymethyl ester prodrugs of the transferable protein farnesyl transferase substrate farnesyl methylenediphosphonate. Bioorganic & Medicinal Chemistry Letters. 14: 4979-82. PMID 15341963 DOI: 10.1016/J.Bmcl.2004.07.017  0.65
2002 Chehade KA, Kiegiel K, Isaacs RJ, Pickett JS, Bowers KE, Fierke CA, Andres DA, Spielmann HP. Photoaffinity analogues of farnesyl pyrophosphate transferable by protein farnesyl transferase. Journal of the American Chemical Society. 124: 8206-19. PMID 12105898 DOI: 10.1021/Ja0124717  0.662
2001 Micali E, Chehade KA, Isaacs RJ, Andres DA, Spielmann HP. Protein farnesyltransferase isoprenoid substrate discrimination is dependent on isoprene double bonds and branched methyl groups. Biochemistry. 40: 12254-65. PMID 11591144 DOI: 10.1021/Bi011133F  0.641
2001 Than C, Morimoto H, Williams PG, Chehade KA, Andres DA, Spielmann HP. Preparation, NMR characterization, and labeling reactions of tritiated triacetoxy sodium borohydride. The Journal of Organic Chemistry. 66: 3602-5. PMID 11348153 DOI: 10.1021/Jo005753I  0.429
2000 Chehade KA, Spielmann HP. Facile and efficient synthesis of 4-azidotetrafluoroaniline: a new photoaffinity reagent. The Journal of Organic Chemistry. 65: 4949-53. PMID 10956477 DOI: 10.1021/Jo000402P  0.511
2000 Chehade KA, Andres DA, Morimoto H, Spielmann HP. Design and synthesis of a transferable farnesyl pyrophosphate analogue to Ras by protein farnesyltransferase. The Journal of Organic Chemistry. 65: 3027-33. PMID 10814193 DOI: 10.1021/Jo991735T  0.627
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