Andrew P. Hinck - Publications

Affiliations: 
1997-2015 University of Texas Health Science Center in San Antonio 
 2015- University of Pittsburgh, Pittsburgh, PA, United States 

70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Huang T, Hinck AP. Production, Isolation, and Structural Analysis of Ligands and Receptors of the TGF-β Superfamily. Methods in Molecular Biology (Clifton, N.J.). 1344: 63-92. PMID 26520118 DOI: 10.1007/978-1-4939-2966-5_4  0.72
2015 Zhang S, Hinck AP, Fitzpatrick PF. The Amino Acid Specificity for Activation of Phenylalanine Hydroxylase Matches the Specificity for Stabilization of Regulatory Domain Dimers. Biochemistry. PMID 26252467 DOI: 10.1021/acs.biochem.5b00616  0.96
2015 Lin AP, Abbas S, Kim SW, Ortega M, Bouamar H, Escobedo Y, Varadarajan P, Qin Y, Sudderth J, Schulz E, Deutsch A, Mohan S, Ulz P, Neumeister P, Rakheja D, ... ... Hinck A, et al. D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2. Nature Communications. 6: 7768. PMID 26178471 DOI: 10.1038/ncomms8768  0.96
2015 Zhuo Y, Cano KE, Wang L, Ilangovan U, Hinck AP, Sousa R, Lafer EM. Nuclear Magnetic Resonance Structural Mapping Reveals Promiscuous Interactions between Clathrin-Box Motif Sequences and the N-Terminal Domain of the Clathrin Heavy Chain. Biochemistry. 54: 2571-80. PMID 25844500 DOI: 10.1021/acs.biochem.5b00065  0.96
2015 Khalkhali-Ellis Z, Kirschmann DA, Seftor EA, Gilgur A, Bodenstine TM, Hinck AP, Hendrix MJ. Divergence(s) in nodal signaling between aggressive melanoma and embryonic stem cells. International Journal of Cancer. Journal International Du Cancer. 136: E242-51. PMID 25204799 DOI: 10.1002/ijc.29198  0.96
2014 Huang T, Schor SL, Hinck AP. Biological activity differences between TGF-β1 and TGF-β3 correlate with differences in the rigidity and arrangement of their component monomers. Biochemistry. 53: 5737-49. PMID 25153513 DOI: 10.1021/bi500647d  0.96
2014 Zhang S, Huang T, Ilangovan U, Hinck AP, Fitzpatrick PF. The solution structure of the regulatory domain of tyrosine hydroxylase. Journal of Molecular Biology. 426: 1483-97. PMID 24361276 DOI: 10.1016/j.jmb.2013.12.015  0.96
2013 Hinck AP, Huang T. TGF-β antagonists: same knot, but different hold. Structure (London, England : 1993). 21: 1269-70. PMID 23931139 DOI: 10.1016/j.str.2013.07.015  0.96
2012 Mahlawat P, Ilangovan U, Biswas T, Sun LZ, Hinck AP. Structure of the Alk1 extracellular domain and characterization of its bone morphogenetic protein (BMP) binding properties. Biochemistry. 51: 6328-41. PMID 22799562 DOI: 10.1021/bi300942x  0.96
2012 Robinson AK, Leal BZ, Nanyes DR, Kaur Y, Ilangovan U, Schirf V, Hinck AP, Demeler B, Kim CA. Human polyhomeotic homolog 3 (PHC3) sterile alpha motif (SAM) linker allows open-ended polymerization of PHC3 SAM. Biochemistry. 51: 5379-86. PMID 22724443 DOI: 10.1021/bi3004318  0.96
2012 Hinck AP. Structural studies of the TGF-βs and their receptors - insights into evolution of the TGF-β superfamily. Febs Letters. 586: 1860-70. PMID 22651914 DOI: 10.1016/j.febslet.2012.05.028  0.96
2012 Sousa R, Jiang J, Lafer EM, Hinck AP, Wang L, Taylor AB, Maes EG. Evaluation of competing J domain:Hsp70 complex models in light of existing mutational and NMR data. Proceedings of the National Academy of Sciences of the United States of America. 109: E734; author reply E. PMID 22403069 DOI: 10.1073/pnas.1120597109  0.96
2012 Robinson AK, Leal BZ, Chadwell LV, Wang R, Ilangovan U, Kaur Y, Junco SE, Schirf V, Osmulski PA, Gaczynska M, Hinck AP, Demeler B, McEwen DG, Kim CA. The growth-suppressive function of the polycomb group protein polyhomeotic is mediated by polymerization of its sterile alpha motif (SAM) domain. The Journal of Biological Chemistry. 287: 8702-13. PMID 22275371 DOI: 10.1074/jbc.M111.336115  0.96
2011 Zuniga JE, Ilangovan U, Mahlawat P, Hinck CS, Huang T, Groppe JC, McEwen DG, Hinck AP. The TβR-I pre-helix extension is structurally ordered in the unbound form and its flanking prolines are essential for binding. Journal of Molecular Biology. 412: 601-18. PMID 21821041 DOI: 10.1016/j.jmb.2011.07.046  0.96
2011 Hinck AP, O'Connor-McCourt MD. Structures of TGF-β receptor complexes: implications for function and therapeutic intervention using ligand traps. Current Pharmaceutical Biotechnology. 12: 2081-98. PMID 21619540 DOI: 10.2174/138920111798808383  0.96
2011 Huang T, David L, Mendoza V, Yang Y, Villarreal M, De K, Sun L, Fang X, López-Casillas F, Wrana JL, Hinck AP. TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs. The Embo Journal. 30: 1263-76. PMID 21423151 DOI: 10.1038/emboj.2011.54  0.96
2011 Wang R, Ilangovan U, Leal BZ, Robinson AK, Amann BT, Tong CV, Berg JM, Hinck AP, Kim CA. Identification of nucleic acid binding residues in the FCS domain of the polycomb group protein polyhomeotic. Biochemistry. 50: 4998-5007. PMID 21351738 DOI: 10.1021/bi101487s  0.96
2011 Li J, Ilangovan U, Daubner SC, Hinck AP, Fitzpatrick PF. Direct evidence for a phenylalanine site in the regulatory domain of phenylalanine hydroxylase. Archives of Biochemistry and Biophysics. 505: 250-5. PMID 20951114 DOI: 10.1016/j.abb.2010.10.009  0.96
2010 Li L, Orner BP, Huang T, Hinck AP, Kiessling LL. Peptide ligands that use a novel binding site to target both TGF-β receptors. Molecular Biosystems. 6: 2392-402. PMID 20890540 DOI: 10.1039/c0mb00115e  0.72
2010 Zhuo Y, Ilangovan U, Schirf V, Demeler B, Sousa R, Hinck AP, Lafer EM. Dynamic interactions between clathrin and locally structured elements in a disordered protein mediate clathrin lattice assembly. Journal of Molecular Biology. 404: 274-90. PMID 20875424 DOI: 10.1016/j.jmb.2010.09.044  0.96
2010 Wang R, Taylor AB, Leal BZ, Chadwell LV, Ilangovan U, Robinson AK, Schirf V, Hart PJ, Lafer EM, Demeler B, Hinck AP, McEwen DG, Kim CA. Polycomb group targeting through different binding partners of RING1B C-terminal domain. Structure (London, England : 1993). 18: 966-75. PMID 20696397 DOI: 10.1016/j.str.2010.04.013  0.96
2010 Hinck AP. Class II cytokine common receptors: something old, something new. Structure (London, England : 1993). 18: 551-2. PMID 20462488 DOI: 10.1016/j.str.2010.04.003  0.96
2010 Radaev S, Zou Z, Huang T, Lafer EM, Hinck AP, Sun PD. Ternary complex of transforming growth factor-beta1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily. The Journal of Biological Chemistry. 285: 14806-14. PMID 20207738 DOI: 10.1074/jbc.M109.079921  0.96
2009 Mendoza V, Vilchis-Landeros MM, Mendoza-Hernández G, Huang T, Villarreal MM, Hinck AP, López-Casillas F, Montiel JL. Betaglycan has two independent domains required for high affinity TGF-beta binding: proteolytic cleavage separates the domains and inactivates the neutralizing activity of the soluble receptor. Biochemistry. 48: 11755-65. PMID 19842711 DOI: 10.1021/bi901528w  0.96
2009 Iakhiaeva E, Hinck CS, Hinck AP, Zwieb C. Characterization of the SRP68/72 interface of human signal recognition particle by systematic site-directed mutagenesis. Protein Science : a Publication of the Protein Society. 18: 2183-95. PMID 19693936 DOI: 10.1002/pro.232  0.96
2009 Garza JA, Ilangovan U, Hinck AP, Barnes LD. Kinetic, dynamic, ligand binding properties, and structural models of a dual-substrate specific nudix hydrolase from Schizosaccharomyces pombe. Biochemistry. 48: 6224-39. PMID 19462967 DOI: 10.1021/bi802266g  0.96
2009 Xu X, Mikhailova M, Ilangovan U, Chen Z, Yu A, Pal S, Hinck AP, Steffensen B. Nuclear magnetic resonance mapping and functional confirmation of the collagen binding sites of matrix metalloproteinase-2. Biochemistry. 48: 5822-31. PMID 19459623 DOI: 10.1021/bi900513h  0.96
2009 Baardsnes J, Hinck CS, Hinck AP, O'Connor-McCourt MD. TbetaR-II discriminates the high- and low-affinity TGF-beta isoforms via two hydrogen-bonded ion pairs. Biochemistry. 48: 2146-55. PMID 19161338 DOI: 10.1021/bi8019004  0.96
2008 Ilangovan U, Bhuiyan SH, Hinck CS, Hoyle JT, Pakhomova ON, Zwieb C, Hinck AP. A. fulgidus SRP54 M-domain. Journal of Biomolecular Nmr. 41: 241-8. PMID 18618268 DOI: 10.1007/s10858-008-9252-4  0.96
2008 Wang R, Ilangovan U, Robinson AK, Schirf V, Schwarz PM, Lafer EM, Demeler B, Hinck AP, Kim CA. Structural transitions of the RING1B C-terminal region upon binding the polycomb cbox domain. Biochemistry. 47: 8007-15. PMID 18616292 DOI: 10.1021/bi800857f  0.96
2008 Verona EV, Tang Y, Millstead TK, Hinck AP, Agyin JK, Sun LZ. Expression, purification and characterization of BG(E)RII: a novel pan-TGFbeta inhibitor. Protein Engineering, Design & Selection : Peds. 21: 463-73. PMID 18499679 DOI: 10.1093/protein/gzn023  0.96
2008 Yin H, Yeh LC, Hinck AP, Lee JC. Characterization of ligand-binding properties of the human BMP type II receptor extracellular domain. Journal of Molecular Biology. 378: 191-203. PMID 18342887 DOI: 10.1016/j.jmb.2008.02.031  0.96
2008 Groppe J, Hinck CS, Samavarchi-Tehrani P, Zubieta C, Schuermann JP, Taylor AB, Schwarz PM, Wrana JL, Hinck AP. Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding. Molecular Cell. 29: 157-68. PMID 18243111 DOI: 10.1016/j.molcel.2007.11.039  0.96
2007 Jiang J, Maes EG, Taylor AB, Wang L, Hinck AP, Lafer EM, Sousa R. Structural basis of J cochaperone binding and regulation of Hsp70. Molecular Cell. 28: 422-33. PMID 17996706 DOI: 10.1016/j.molcel.2007.08.022  0.96
2007 Loverde PT, Osman A, Hinck A. Schistosoma mansoni: TGF-beta signaling pathways. Experimental Parasitology. 117: 304-17. PMID 17643432 DOI: 10.1016/j.exppara.2007.06.002  0.96
2007 Chang SL, Hinck AP, Ishima R. Model-free analysis for large proteins at high magnetic field strengths. Journal of Biomolecular Nmr. 38: 315-24. PMID 17593525 DOI: 10.1007/s10858-007-9171-9  0.96
2006 De Crescenzo G, Hinck CS, Shu Z, Zúñiga J, Yang J, Tang Y, Baardsnes J, Mendoza V, Sun L, López-Casillas F, O'Connor-McCourt M, Hinck AP. Three key residues underlie the differential affinity of the TGFbeta isoforms for the TGFbeta type II receptor. Journal of Molecular Biology. 355: 47-62. PMID 16300789 DOI: 10.1016/j.jmb.2005.10.022  0.96
2006 De Crescenzo G, Hinck CS, Shu Z, Zúñiga J, Yang J, Tang Y, Baardsnes J, Mendoza V, Sun L, López-Casillas F, O'Connor-McCourt M, Hinck AP. Corrigendum to "Three Key Residues Underlie the Differential Affinity of the TGFβ Isoforms for the TGFβ Type II Receptor" [J. Mol. Biol. (2006) 355, 47-62] (DOI:10.1016/j.jmb.2005.10.022) Journal of Molecular Biology. 359: 508. DOI: 10.1016/j.jmb.2006.02.080  0.96
2005 Zúñiga JE, Groppe JC, Cui Y, Hinck CS, Contreras-Shannon V, Pakhomova ON, Yang J, Tang Y, Mendoza V, López-Casillas F, Sun L, Hinck AP. Assembly of TbetaRI:TbetaRII:TGFbeta ternary complex in vitro with receptor extracellular domains is cooperative and isoform-dependent. Journal of Molecular Biology. 354: 1052-68. PMID 16289576 DOI: 10.1016/j.jmb.2005.10.014  0.96
2005 Yin H, Ilangovan U, Hinck AP, Lee JC. Sequential resonance assignment of the human BMP type II receptor extracellular domain. Journal of Biomolecular Nmr. 32: 336. PMID 16211489 DOI: 10.1007/s10858-005-8871-2  0.96
2005 Ilangovan U, Ding W, Zhong Y, Wilson CL, Groppe JC, Trbovich JT, Zúñiga J, Demeler B, Tang Q, Gao G, Mulder KM, Hinck AP. Structure and dynamics of the homodimeric dynein light chain km23. Journal of Molecular Biology. 352: 338-54. PMID 16083906 DOI: 10.1016/j.jmb.2005.07.002  0.96
2004 Yin J, Huang Q, Pakhomova ON, Hinck AP, Zwieb C. The conserved adenosine in helix 6 of Archaeoglobus fulgidus signal recognition particle RNA initiates SRP assembly. Archaea (Vancouver, B.C.). 1: 269-75. PMID 15810437  0.96
2004 Borges CR, Qi J, Wu W, Torng E, Hinck AP, Watson JT. Algorithm-assisted elucidation of disulfide structure: application of the negative signature mass algorithm to mass-mapping the disulfide structure of the 12-cysteine transforming growth factor beta type II receptor extracellular domain. Analytical Biochemistry. 329: 91-103. PMID 15136171 DOI: 10.1016/j.ab.2004.01.037  0.96
2004 Ilangovan U, Deep S, Hinck CS, Hinck AP. Sequential resonance assignments of the extracellular domain of the human TGFbeta type II receptor in complex with monomeric TGFbeta3. Journal of Biomolecular Nmr. 29: 103-4. PMID 15017149 DOI: 10.1023/B:JNMR.0000019468.50957.42  0.96
2003 Deep S, Walker KP, Shu Z, Hinck AP. Solution structure and backbone dynamics of the TGFbeta type II receptor extracellular domain. Biochemistry. 42: 10126-39. PMID 12939140 DOI: 10.1021/bi034366a  0.96
2002 Pakhomova ON, Deep S, Huang Q, Zwieb C, Hinck AP. Solution structure of protein SRP19 of Archaeoglobus fulgidus signal recognition particle. Journal of Molecular Biology. 317: 145-58. PMID 11916385 DOI: 10.1006/jmbi.2002.5411  0.96
2002 Benavides-Garcia MG, Rivera EV, Ramos W, Hinck AP, Nall BT. Backbone sequential resonance assignments of yeast iso-2 cytochrome c, reduced and oxidized forms. Journal of Biomolecular Nmr. 22: 93-4. PMID 11885986 DOI: 10.1023/A:1013801402362  0.96
2002 Hart PJ, Deep S, Taylor AB, Shu Z, Hinck CS, Hinck AP. Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex. Nature Structural Biology. 9: 203-8. PMID 11850637 DOI: 10.1038/nsb766  0.96
2001 Miller RT, Hinck AP. Characterization of hydride transfer to flavin adenine dinucleotide in neuronal nitric oxide synthase reductase domain: geometric relationship between the nicotinamide and isoalloxazine rings. Archives of Biochemistry and Biophysics. 395: 129-35. PMID 11673874 DOI: 10.1006/abbi.2001.2588  0.96
2001 Pakhomova ON, Cui Y, Zwieb C, Hinck AP. Sequence-specific 1H, 13C and 15N signal assignments and secondary structure of Archaeoglobus fulgidus SRP19 [4] Journal of Biomolecular Nmr. 20: 187-188. PMID 11495253 DOI: 10.1023/A:1011243402698  0.96
2001 Bhuiyan SH, Pakhomova ON, Hinck AP, Zwieb C. Complexes with truncated RNAs from the large domain of Archaeoglobus fulgidus signal recognition particle Fems Microbiology Letters. 198: 105-110. PMID 11430398 DOI: 10.1016/S0378-1097(01)00141-0  0.96
2000 Hinck AP, Walker KP, Martin NR, Deep S, Hinck CS, Freedberg DI. Letter to the editor: Sequential resonance assignments of the extracellular ligand binding domain of the human TGF-β type II receptor [5] Journal of Biomolecular Nmr. 18: 369-370. PMID 11200535 DOI: 10.1023/A:1026775321886  0.96
1997 Hinck AP, Markus MA, Huang S, Grzesiek S, Kustonovich I, Draper DE, Torchia DA. The RNA binding domain of ribosomal protein L11: three-dimensional structure of the RNA-bound form of the protein and its interaction with 23 S rRNA. Journal of Molecular Biology. 274: 101-13. PMID 9398519 DOI: 10.1006/jmbi.1997.1379  0.96
1997 Markus MA, Hinck AP, Huang S, Draper DE, Torchia DA. High resolution solution structure of ribosomal protein L11-C76, a helical protein with a flexible loop that becomes structured upon binding to RNA. Nature Structural Biology. 4: 70-7. PMID 8989327 DOI: 10.1038/nsb0197-70  0.96
1996 Qian SW, Burmester JK, Tsang MLS, Weatherbee JA, Hinck AP, Ohlsen DJ, Sporn MB, Roberts AB. Binding affinity of transforming growth factor-β for its type II receptor is determined by the C-terminal region of the molecule Journal of Biological Chemistry. 271: 30656-30662. PMID 8940041 DOI: 10.1074/jbc.271.48.30656  0.96
1996 Yamazaki T, Hinck AP, Wang YX, Nicholson LK, Torchia DA, Wingfield P, Stahl SJ, Kaufman JD, Chang CH, Domaille PJ, Lam PY. Three-dimensional solution structure of the HIV-1 protease complexed with DMP323, a novel cyclic urea-type inhibitor, determined by nuclear magnetic resonance spectroscopy. Protein Science : a Publication of the Protein Society. 5: 495-506. PMID 8868486 DOI: 10.1002/pro.5560050311  0.96
1996 Hinck AP, Truckses DM, Markley JL. Engineered disulfide bonds in staphylococcal nuclease: effects on the stability and conformation of the folded protein. Biochemistry. 35: 10328-38. PMID 8756688 DOI: 10.1021/bi960309o  0.96
1996 Hinck AP, Archer SJ, Qian SW, Roberts AB, Sporn MB, Weatherbee JA, Tsang ML, Lucas R, Zhang BL, Wenker J, Torchia DA. Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2. Biochemistry. 35: 8517-34. PMID 8679613 DOI: 10.1021/bi9604946  0.96
1995 Grzesiek S, Kuboniwa H, Hinck AP, Bax A. Multiple-quantum line narrowing for measurement of Hα-Hβ J couplings in isotopically enriched proteins Journal of the American Chemical Society. 117: 5312-5315.  0.96
1994 Markley JL, Prehoda K, Truckses D, Wang J, Hinck AP, Loh SN, Walkenhorst WF. Case study of protein structure, stability, and function: NMR investigations of the proline residues in staphylococcal nuclease Pure and Applied Chemistry. 66: 65-69. DOI: 10.1351/pac199466010065  0.96
1993 Royer CA, Hinck AP, Loh SN, Prehoda KE, Peng X, Jonas J, Markley JL. Effects of amino acid substitutions on the pressure denaturation of staphylococcal nuclease as monitored by fluorescence and nuclear magnetic resonance spectroscopy. Biochemistry. 32: 5222-32. PMID 8494899 DOI: 10.1021/bi00070a034  0.96
1993 Hinck AP, Walkenhorst WF, Westler WM, Choe S, Markley JL. Overexpression and purification of avian ovomucoid third domains in Escherichia coli. Protein Engineering. 6: 221-7. PMID 8475048 DOI: 10.1093/protein/6.2.221  0.96
1993 Hinck AP, Eberhardt ES, Markley JL. NMR strategy for determining Xaa-Pro peptide bond configurations in proteins: mutants of staphylococcal nuclease with altered configuration at proline-117. Biochemistry. 32: 11810-8. PMID 8218252 DOI: 10.1021/bi00095a009  0.96
1992 Eberhardt ES, Loh SN, Hinck AP, Raines RT. Solvent Effects on the Energetics of Prolyl Peptide Bond Isomerization. Journal of the American Chemical Society. 114: 5437-5439. PMID 21451730 DOI: 10.1021/ja00039a072  0.96
1992 Wang JF, Hinck AP, Loh SN, LeMaster DM, Markley JL. Solution studies of staphylococcal nuclease H124L. 2. 1H, 13C, and 15N chemical shift assignments for the unligated enzyme and analysis of chemical shift changes that accompany formation of the nuclease-thymidine 3',5'-bisphosphate-calcium ternary complex. Biochemistry. 31: 921-36. PMID 1731949 DOI: 10.1021/bi00118a039  0.96
1990 Alexandrescu AT, Hinck AP, Markley JL. Coupling between local structure and global stability of a protein: mutants of staphylococcal nuclease. Biochemistry. 29: 4516-25. PMID 2372535 DOI: 10.1021/bi00471a003  0.96
1990 Wang JF, Hinck AP, Loh SN, Markley JL. Two-dimensional NMR studies of staphylococcal nuclease: evidence for conformational heterogeneity from hydrogen-1, carbon-13, and nitrogen-15 spin system assignments of the aromatic amino acids in the nuclease H124L-thymidine 3',5'-bisphosphate-Ca2+ ternary complex. Biochemistry. 29: 4242-53. PMID 2361141 DOI: 10.1021/bi00469a029  0.96
1990 Wang JF, Hinck AP, Loh SN, Markley JL. Two-dimensional NMR studies of staphylococcal nuclease. 2. Sequence-specific assignments of carbon-13 and nitrogen-15 signals from the nuclease H124L-thymidine 3',5'-bisphosphate-Ca2+ ternary complex. Biochemistry. 29: 102-13. PMID 2322533 DOI: 10.1021/bi00453a012  0.96
1990 Hinck AP, Loh SN, Wang J, Markley JL. Histidine 121 of staphylococcal nuclease. Correction of the H(δ2) 1H NMR assignment and reinterpretation of the role this residue plays in conformational heterogeneity of the protein Journal of the American Chemical Society. 112: 9031-9034. DOI: 10.1021/ja00181a001  0.96
1990 Hinck AP, Loh SN, Wang J, Markley JL. Histidine 121 of staphylococcal nuclease. Correction of the Hδ2 1H NMR assignment and reinterpretation of the role this residue plays in conformational heterogeneity of the protein Journal of the American Chemical Society. 112.  0.96
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