Stephen C. West - Publications

Clare Hall Laboratories Imperial Cancer Research Fund 

235 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Ho HN, West SC. Generation of double Holliday junction DNAs and their dissolution/resolution within a chromatin context. Proceedings of the National Academy of Sciences of the United States of America. 119: e2123420119. PMID 35452329 DOI: 10.1073/pnas.2123420119  0.499
2022 Caballero M, Ge T, Rebelo AR, Seo S, Kim S, Brooks K, Zuccaro M, Kanagaraj R, Vershkov D, Kim D, Smogorzewska A, Smolka M, Benvenisty N, West SC, Egli D, et al. Comprehensive analysis of DNA replication timing across 184 cell lines suggests a role for MCM10 in replication timing regulation. Human Molecular Genetics. PMID 35394024 DOI: 10.1093/hmg/ddac082  0.363
2021 Young SJ, West SC. Coordinated roles of SLX4 and MutSβ in DNA repair and the maintenance of genome stability. Critical Reviews in Biochemistry and Molecular Biology. 1-31. PMID 33596761 DOI: 10.1080/10409238.2021.1881433  0.558
2021 West SC, Kowalczykowski SC. Charles M. Radding: A love of science and art. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33495365 DOI: 10.1073/pnas.2025935118  0.427
2020 Hewitt G, Borel V, Segura-Bayona S, Takaki T, Ruis P, Bellelli R, Lehmann LC, Sommerova L, Vancevska A, Tomas-Loba A, Zhu K, Cooper C, Fugger K, Patel H, Goldstone R, ... ... West SC, et al. Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD. Molecular Cell. PMID 33333017 DOI: 10.1016/j.molcel.2020.12.006  0.738
2020 Young SJ, Sebald M, Shah Punatar R, Larin M, Masino L, Rodrigo-Brenni MC, Liang CC, West SC. MutSβ Stimulates Holliday Junction Resolution by the SMX Complex. Cell Reports. 33: 108289. PMID 33086055 DOI: 10.1016/j.celrep.2020.108289  0.428
2020 van Wietmarschen N, Sridharan S, Nathan WJ, Tubbs A, Chan EM, Callen E, Wu W, Belinky F, Tripathi V, Wong N, Foster K, Noorbakhsh J, Garimella K, Cruz-Migoni A, Sommers JA, ... ... West SC, et al. Repeat expansions confer WRN dependence in microsatellite-unstable cancers. Nature. PMID 32999459 DOI: 10.1038/s41586-020-2769-8  0.441
2018 Chan YW, West SC. A new class of ultrafine anaphase bridges generated by homologous recombination. Cell Cycle (Georgetown, Tex.). 1-9. PMID 30253678 DOI: 10.1080/15384101.2018.1515555  0.593
2018 Shah Punatar R, West SC. Preparation and Resolution of Holliday Junction DNA Recombination Intermediates. Methods in Enzymology. 600: 569-590. PMID 29458775 DOI: 10.1016/Bs.Mie.2017.11.022  0.609
2018 Chan YW, West SC. GEN1 Endonuclease: Purification and Nuclease Assays. Methods in Enzymology. 600: 527-542. PMID 29458773 DOI: 10.1016/Bs.Mie.2017.11.020  0.629
2018 West SC, Chan YW. Genome Instability as a Consequence of Defects in the Resolution of Recombination Intermediates. Cold Spring Harbor Symposia On Quantitative Biology. PMID 29348327 DOI: 10.1101/Sqb.2017.82.034256  0.468
2018 Chan YW, Fugger K, West SC. Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations. Nature Cell Biology. 20: 92-103. PMID 29255170 DOI: 10.1038/S41556-017-0011-1  0.524
2017 Matos J, West SC. Analysis of Structure-Selective Endonuclease Activities From Yeast and Human Extracts. Methods in Enzymology. 591: 271-286. PMID 28645372 DOI: 10.1016/Bs.Mie.2017.03.005  0.517
2017 Muñoz-Galván S, Tous C, Blanco MG, Schwartz EK, Ehmsen KT, West SC, Heyer WD, Aguilera A. Correction for Muñoz-Galván et al., "Distinct Roles of Mus81, Yen1, Slx1-Slx4, and Rad1 Nucleases in the Repair of Replication-Born Double-Strand Breaks by Sister Chromatid Exchange". Molecular and Cellular Biology. 37. PMID 28512214 DOI: 10.1128/Mcb.00161-17  0.389
2017 Wyatt HD, Laister RC, Martin SR, Arrowsmith CH, West SC. The SMX DNA Repair Tri-nuclease. Molecular Cell. 65: 848-860.e11. PMID 28257701 DOI: 10.1016/J.Molcel.2017.01.031  0.554
2017 Shah Punatar R, Martin MJ, Wyatt HD, Chan YW, West SC. Resolution of single and double Holliday junction recombination intermediates by GEN1. Proceedings of the National Academy of Sciences of the United States of America. PMID 28049850 DOI: 10.1073/Pnas.1619790114  0.628
2016 Fugger K, West SC. Keeping homologous recombination in check. Cell Research. PMID 26902288 DOI: 10.1038/Cr.2016.25  0.499
2015 Chan YW, West S. GEN1 promotes Holliday junction resolution by a coordinated nick and counter-nick mechanism. Nucleic Acids Research. 43: 10882-92. PMID 26578604 DOI: 10.1093/Nar/Gkv1207  0.573
2015 West SC, Blanco MG, Chan YW, Matos J, Sarbajna S, Wyatt HD. Resolution of Recombination Intermediates: Mechanisms and Regulation. Cold Spring Harbor Symposia On Quantitative Biology. PMID 26370409 DOI: 10.1101/Sqb.2015.80.027649  0.46
2015 Gaur V, Wyatt HD, Komorowska W, Szczepanowski RH, de Sanctis D, Gorecka KM, West SC, Nowotny M. Structural and Mechanistic Analysis of the Slx1-Slx4 Endonuclease. Cell Reports. PMID 25753413 DOI: 10.1016/J.Celrep.2015.02.019  0.503
2014 Shahid T, Soroka J, Kong EH, Malivert L, McIlwraith MJ, Pape T, West SC, Zhang X. Structure and mechanism of action of the BRCA2 breast cancer tumor suppressor. Nature Structural & Molecular Biology. 21: 962-8. PMID 25282148 DOI: 10.1038/Nsmb.2899  0.482
2014 Chan YW, West SC. Spatial control of the GEN1 Holliday junction resolvase ensures genome stability. Nature Communications. 5: 4844. PMID 25209024 DOI: 10.1038/Ncomms5844  0.366
2014 Wyatt HD, West SC. Holliday junction resolvases. Cold Spring Harbor Perspectives in Biology. 6: a023192. PMID 25183833 DOI: 10.1101/Cshperspect.A023192  0.632
2014 Sarbajna S, West SC. Holliday junction processing enzymes as guardians of genome stability. Trends in Biochemical Sciences. 39: 409-19. PMID 25131815 DOI: 10.1016/J.Tibs.2014.07.003  0.563
2014 Sarbajna S, Davies D, West SC. Roles of SLX1-SLX4, MUS81-EME1, and GEN1 in avoiding genome instability and mitotic catastrophe. Genes & Development. 28: 1124-36. PMID 24831703 DOI: 10.1101/Gad.238303.114  0.404
2014 Pepe A, West SC. MUS81-EME2 promotes replication fork restart Cell Reports. 7: 1048-P1055. PMID 24813886 DOI: 10.1016/J.Celrep.2014.04.007  0.43
2014 Matos J, West SC. Holliday junction resolution: regulation in space and time. Dna Repair. 19: 176-81. PMID 24767945 DOI: 10.1016/J.Dnarep.2014.03.013  0.488
2014 Blanco MG, Matos J, West SC. Dual control of Yen1 nuclease activity and cellular localization by Cdk and Cdc14 prevents genome instability. Molecular Cell. 54: 94-106. PMID 24631285 DOI: 10.1016/J.Molcel.2014.02.011  0.452
2014 Pepe A, West SC. Substrate specificity of the MUS81-EME2 structure selective endonuclease Nucleic Acids Research. 42: 3833-3845. PMID 24371268 DOI: 10.1093/Nar/Gkt1333  0.481
2013 Wyatt HD, Sarbajna S, Matos J, West SC. Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells. Molecular Cell. 52: 234-47. PMID 24076221 DOI: 10.1016/J.Molcel.2013.08.035  0.521
2013 Coulthard R, Deans AJ, Swuec P, Bowles M, Costa A, West SC, McDonald NQ. Architecture and DNA recognition elements of the Fanconi anemia FANCM-FAAP24 complex. Structure (London, England : 1993). 21: 1648-58. PMID 23932590 DOI: 10.1016/J.Str.2013.07.006  0.6
2013 Zilio N, Williamson CT, Eustermann S, Shah R, West SC, Neuhaus D, Ulrich HD. DNA-dependent SUMO modification of PARP-1. Dna Repair. 12: 761-73. PMID 23871147 DOI: 10.1016/J.Dnarep.2013.07.001  0.573
2013 Matos J, Blanco MG, West SC. Cell-cycle kinases coordinate the resolution of recombination intermediates with chromosome segregation. Cell Reports. 4: 76-86. PMID 23810555 DOI: 10.1016/J.Celrep.2013.05.039  0.365
2013 Yüce Ö, West SC. Senataxin, defective in the neurodegenerative disorder ataxia with oculomotor apraxia 2, lies at the interface of transcription and the DNA damage response. Molecular and Cellular Biology. 33: 406-17. PMID 23149945 DOI: 10.1128/Mcb.01195-12  0.544
2012 Muñoz-Galván S, Tous C, Blanco MG, Schwartz EK, Ehmsen KT, West SC, Heyer WD, Aguilera A. Distinct roles of Mus81, Yen1, Slx1-Slx4, and Rad1 nucleases in the repair of replication-born double-strand breaks by sister chromatid exchange. Molecular and Cellular Biology. 32: 1592-603. PMID 22354996 DOI: 10.1128/Mcb.00111-12  0.599
2012 Blackford AN, Schwab RA, Nieminuszczy J, Deans AJ, West SC, Niedzwiedz W. The DNA translocase activity of FANCM protects stalled replication forks. Human Molecular Genetics. 21: 2005-16. PMID 22279085 DOI: 10.1093/Hmg/Dds013  0.552
2012 West SC. Links Between Defective DNA Strand Break Repair and Genome Instability in Fanconi Anemia Blood. 120: SCI-2-SCI-2. DOI: 10.1182/Blood.V120.21.Sci-2.Sci-2  0.621
2011 Matos J, Blanco MG, Maslen S, Skehel JM, West SC. Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis. Cell. 147: 158-72. PMID 21962513 DOI: 10.1016/J.Cell.2011.08.032  0.449
2011 Deans AJ, West SC. DNA interstrand crosslink repair and cancer. Nature Reviews. Cancer. 11: 467-80. PMID 21701511 DOI: 10.1038/Nrc3088  0.531
2011 Wechsler T, Newman S, West SC. Aberrant chromosome morphology in human cells defective for Holliday junction resolution. Nature. 471: 642-6. PMID 21399624 DOI: 10.1038/Nature09790  0.44
2010 Thorslund T, McIlwraith MJ, Compton SA, Lekomtsev S, Petronczki M, Griffith JD, West SC. The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA. Nature Structural & Molecular Biology. 17: 1263-5. PMID 20729858 DOI: 10.1038/Nsmb.1905  0.549
2010 Rass U, Compton SA, Matos J, Singleton MR, Ip SC, Blanco MG, Griffith JD, West SC. Mechanism of Holliday junction resolution by the human GEN1 protein. Genes & Development. 24: 1559-69. PMID 20634321 DOI: 10.1101/Gad.585310  0.503
2010 MacKay C, Déclais AC, Lundin C, Agostinho A, Deans AJ, MacArtney TJ, Hofmann K, Gartner A, West SC, Helleday T, Lilley DM, Rouse J. Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2. Cell. 142: 65-76. PMID 20603015 DOI: 10.1016/J.Cell.2010.06.021  0.63
2010 Wyatt HD, West SC, Beattie TL. InTERTpreting telomerase structure and function. Nucleic Acids Research. 38: 5609-22. PMID 20460453 DOI: 10.1093/Nar/Gkq370  0.346
2010 Youds JL, Mets DG, McIlwraith MJ, Martin JS, Ward JD, ONeil NJ, Rose AM, West SC, Meyer BJ, Boulton SJ. RTEL-1 enforces meiotic crossover interference and homeostasis. Science (New York, N.Y.). 327: 1254-8. PMID 20203049 DOI: 10.1126/Science.1183112  0.318
2010 Blanco MG, Matos J, Rass U, Ip SC, West SC. Functional overlap between the structure-specific nucleases Yen1 and Mus81-Mms4 for DNA-damage repair in S. cerevisiae. Dna Repair. 9: 394-402. PMID 20106725 DOI: 10.1016/J.Dnarep.2009.12.017  0.626
2010 Eustermann S, Brockmann C, Mehrotra PV, Yang JC, Loakes D, West SC, Ahel I, Neuhaus D. Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose). Nature Structural & Molecular Biology. 17: 241-3. PMID 20098424 DOI: 10.1038/Nsmb.1747  0.677
2010 Lorenz A, West SC, Whitby MC. The human Holliday junction resolvase GEN1 rescues the meiotic phenotype of a Schizosaccharomyces pombe mus81 mutant. Nucleic Acids Research. 38: 1866-73. PMID 20040574 DOI: 10.1093/Nar/Gkp1179  0.378
2009 Deans AJ, West SC. FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia. Molecular Cell. 36: 943-53. PMID 20064461 DOI: 10.1016/J.Molcel.2009.12.006  0.485
2009 Ahel D, Horejsí Z, Wiechens N, Polo SE, Garcia-Wilson E, Ahel I, Flynn H, Skehel M, West SC, Jackson SP, Owen-Hughes T, Boulton SJ. Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1. Science (New York, N.Y.). 325: 1240-3. PMID 19661379 DOI: 10.1126/Science.1177321  0.736
2009 West SC. The search for a human Holliday junction resolvase. Biochemical Society Transactions. 37: 519-26. PMID 19442245 DOI: 10.1042/Bst0370519  0.492
2009 Poulet A, Buisson R, Faivre-Moskalenko C, Koelblen M, Amiard S, Montel F, Cuesta-Lopez S, Bornet O, Guerlesquin F, Godet T, Moukhtar J, Argoul F, Déclais AC, Lilley DM, Ip SC, ... West SC, et al. TRF2 promotes, remodels and protects telomeric Holliday junctions. The Embo Journal. 28: 641-51. PMID 19197240 DOI: 10.1038/Emboj.2009.11  0.454
2008 Ip SC, Rass U, Blanco MG, Flynn HR, Skehel JM, West SC. Identification of Holliday junction resolvases from humans and yeast. Nature. 456: 357-61. PMID 19020614 DOI: 10.1038/Nature07470  0.626
2008 Collis SJ, Ciccia A, Deans AJ, Ho?ejší Z, Martin JS, Maslen SL, Skehel JM, Elledge SJ, West SC, Boulton SJ. FANCM and FAAP24 Function in ATR-Mediated Checkpoint Signaling Independently of the Fanconi Anemia Core Complex Molecular Cell. 32: 313-324. PMID 18995830 DOI: 10.1016/J.Molcel.2008.10.014  0.541
2008 Barber LJ, Youds JL, Ward JD, McIlwraith MJ, O'Neil NJ, Petalcorin MI, Martin JS, Collis SJ, Cantor SB, Auclair M, Tissenbaum H, West SC, Rose AM, Boulton SJ. RTEL1 maintains genomic stability by suppressing homologous recombination. Cell. 135: 261-71. PMID 18957201 DOI: 10.1016/J.Cell.2008.08.016  0.489
2008 Liu Y, West SC. More complexity to the Bloom's syndrome complex. Genes & Development. 22: 2737-42. PMID 18923071 DOI: 10.1101/Gad.1732808  0.38
2008 Rass U, Ahel I, West SC. Molecular mechanism of DNA deadenylation by the neurological disease protein aprataxin. The Journal of Biological Chemistry. 283: 33994-4001. PMID 18836178 DOI: 10.1074/Jbc.M807124200  0.772
2008 Ciccia A, McDonald N, West SC. Structural and functional relationships of the XPF/MUS81 family of proteins. Annual Review of Biochemistry. 77: 259-87. PMID 18518821 DOI: 10.1146/Annurev.Biochem.77.070306.102408  0.536
2008 Richard DJ, Bolderson E, Cubeddu L, Wadsworth RI, Savage K, Sharma GG, Nicolette ML, Tsvetanov S, McIlwraith MJ, Pandita RK, Takeda S, Hay RT, Gautier J, West SC, Paull TT, et al. Single-stranded DNA-binding protein hSSB1 is critical for genomic stability. Nature. 453: 677-81. PMID 18449195 DOI: 10.1038/Nature06883  0.64
2008 McIlwraith MJ, West SC. DNA repair synthesis facilitates RAD52-mediated second-end capture during DSB repair. Molecular Cell. 29: 510-6. PMID 18313388 DOI: 10.1016/J.Molcel.2007.11.037  0.629
2008 Ahel I, Ahel D, Matsusaka T, Clark AJ, Pines J, Boulton SJ, West SC. Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins. Nature. 451: 81-5. PMID 18172500 DOI: 10.1038/Nature06420  0.75
2008 Thorslund T, West SC. BRCA2: a universal recombinase regulator. Oncogene. 26: 7720-30. PMID 18066084 DOI: 10.1038/Sj.Onc.1210870  0.49
2008 Thorslund T, Esashi F, West S. Interactions between BRCA2 protein and the meiosis-specific recombinase DMC1 Breast Cancer Research. 10: 3. DOI: 10.1186/Bcr1887  0.485
2007 Stewart GS, Stankovic T, Byrd PJ, Wechsler T, Miller ES, Huissoon A, Drayson MT, West SC, Elledge SJ, Taylor AM. RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling. Proceedings of the National Academy of Sciences of the United States of America. 104: 16910-5. PMID 17940005 DOI: 10.1073/Pnas.0708408104  0.568
2007 Rass U, Ahel I, West SC. Defective DNA repair and neurodegenerative disease. Cell. 130: 991-1004. PMID 17889645 DOI: 10.1016/J.Cell.2007.08.043  0.709
2007 Thorslund T, Esashi F, West SC. Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1. The Embo Journal. 26: 2915-22. PMID 17541404 DOI: 10.1038/Sj.Emboj.7601739  0.396
2007 Esashi F, Galkin VE, Yu X, Egelman EH, West SC. Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2. Nature Structural & Molecular Biology. 14: 468-74. PMID 17515904 DOI: 10.1038/Nsmb1245  0.419
2007 Kuznetsov S, Pellegrini M, Shuda K, Fernandez-Capetillo O, Liu Y, Martin BK, Burkett S, Southon E, Pati D, Tessarollo L, West SC, Donovan PJ, Nussenzweig A, Sharan SK. RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females. The Journal of Cell Biology. 176: 581-92. PMID 17312021 DOI: 10.1083/Jcb.200608130  0.408
2007 Ciccia A, Ling C, Coulthard R, Yan Z, Xue Y, Meetei AR, Laghmani el H, Joenje H, McDonald N, de Winter JP, Wang W, West SC. Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM. Molecular Cell. 25: 331-43. PMID 17289582 DOI: 10.1016/J.Molcel.2007.01.003  0.601
2007 Rass U, Ahel I, West SC. Actions of aprataxin in multiple DNA repair pathways. The Journal of Biological Chemistry. 282: 9469-74. PMID 17276982 DOI: 10.1074/Jbc.M611489200  0.781
2007 Liu Y, Tarsounas M, O'regan P, West SC. Role of RAD51C and XRCC3 in genetic recombination and DNA repair. The Journal of Biological Chemistry. 282: 1973-9. PMID 17114795 DOI: 10.1074/Jbc.M609066200  0.568
2006 Ahel I, Rass U, El-Khamisy SF, Katyal S, Clements PM, McKinnon PJ, Caldecott KW, West SC. The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates. Nature. 443: 713-6. PMID 16964241 DOI: 10.1038/Nature05164  0.779
2006 Rass U, West SC. Synthetic junctions as tools to identify and characterize Holliday junction resolvases. Methods in Enzymology. 408: 485-501. PMID 16793388 DOI: 10.1016/S0076-6879(06)08030-X  0.537
2006 Rodrigue A, Lafrance M, Gauthier MC, McDonald D, Hendzel M, West SC, Jasin M, Masson JY. Interplay between human DNA repair proteins at a unique double-strand break in vivo. The Embo Journal. 25: 222-31. PMID 16395335 DOI: 10.1038/Sj.Emboj.7600914  0.607
2006 West S, Esashi F. Regulation of recombinational repair by the familial breast cancer susceptibility protein BRCA2. Breast Cancer Research. 8: 1-1. DOI: 10.1186/Bcr1548  0.334
2005 McIlwraith MJ, Mcllwraith MJ, Vaisman A, Liu Y, Fanning E, Woodgate R, West SC. Human DNA polymerase eta promotes DNA synthesis from strand invasion intermediates of homologous recombination. Molecular Cell. 20: 783-92. PMID 16337601 DOI: 10.1016/J.Molcel.2005.10.001  0.597
2005 Galkin VE, Esashi F, Yu X, Yang S, West SC, Egelman EH. BRCA2 BRC motifs bind RAD51-DNA filaments. Proceedings of the National Academy of Sciences of the United States of America. 102: 8537-42. PMID 15937124 DOI: 10.1073/Pnas.0407266102  0.507
2005 Tarsounas M, West SC. Recombination at mammalian telomeres: an alternative mechanism for telomere protection and elongation. Cell Cycle (Georgetown, Tex.). 4: 672-4. PMID 15846103 DOI: 10.4161/Cc.4.5.1689  0.567
2005 Esashi F, Christ N, Gannon J, Liu Y, Hunt T, Jasin M, West SC. CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair. Nature. 434: 598-604. PMID 15800615 DOI: 10.1038/Nature03404  0.48
2004 Liu Y, West SC. Happy Hollidays: 40th anniversary of the Holliday junction. Nature Reviews. Molecular Cell Biology. 5: 937-44. PMID 15520813 DOI: 10.1038/Nrm1502  0.51
2004 Garcia PL, Liu Y, Jiricny J, West SC, Janscak P. Human RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptide. The Embo Journal. 23: 2882-91. PMID 15241474 DOI: 10.1038/Sj.Emboj.7600301  0.636
2004 Surrallés J, Jackson SP, Jasin M, Kastan MB, West SC, Joenje H. Molecular cross-talk among chromosome fragility syndromes. Genes & Development. 18: 1359-70. PMID 15198978 DOI: 10.1101/Gad.1216304  0.364
2004 Hussain S, Wilson JB, Medhurst AL, Hejna J, Witt E, Ananth S, Davies A, Masson JY, Moses R, West SC, de Winter JP, Ashworth A, Jones NJ, Mathew CG. Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways. Human Molecular Genetics. 13: 1241-8. PMID 15115758 DOI: 10.1093/Hmg/Ddh135  0.613
2004 Tarsounas M, Muñoz P, Claas A, Smiraldo PG, Pittman DL, Blasco MA, West SC. Telomere maintenance requires the RAD51D recombination/repair protein. Cell. 117: 337-47. PMID 15109494 DOI: 10.1016/S0092-8674(04)00337-X  0.551
2004 Tarsounas M, Davies AA, West SC. RAD51 localization and activation following DNA damage. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 359: 87-93. PMID 15065660 DOI: 10.1098/Rstb.2003.1368  0.64
2004 Liu Y, Stasiak AZ, Masson JY, McIlwraith MJ, Stasiak A, West SC. Conformational changes modulate the activity of human RAD51 protein. Journal of Molecular Biology. 337: 817-27. PMID 15033353 DOI: 10.1016/J.Jmb.2004.02.022  0.628
2004 Constantinou A, West SC. Holliday junction branch migration and resolution assays. Methods in Molecular Biology (Clifton, N.J.). 262: 239-53. PMID 14769966 DOI: 10.1385/1-59259-761-0:239  0.526
2004 Liu Y, Masson JY, Shah R, O'Regan P, West SC. RAD51C is required for Holliday junction processing in mammalian cells. Science (New York, N.Y.). 303: 243-6. PMID 14716019 DOI: 10.1126/Science.1093037  0.513
2003 Abraham J, Lemmers B, Hande MP, Moynahan ME, Chahwan C, Ciccia A, Essers J, Hanada K, Chahwan R, Khaw AK, McPherson P, Shehabeldin A, Laister R, Arrowsmith C, Kanaar R, ... West SC, et al. Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells. The Embo Journal. 22: 6137-47. PMID 14609959 DOI: 10.1093/Emboj/Cdg580  0.611
2003 West SC. Molecular views of recombination proteins and their control. Nature Reviews. Molecular Cell Biology. 4: 435-45. PMID 12778123 DOI: 10.1038/Nrm1127  0.548
2003 West SC, Chappell C, Hanakahi LA, Masson JY, McIlwraith MJ, Van Dyck E. Double-strand break repair in human cells. Cold Spring Harbor Symposia On Quantitative Biology. 65: 315-21. PMID 12760045 DOI: 10.1101/Sqb.2000.65.315  0.458
2003 Ciccia A, Constantinou A, West SC. Identification and characterization of the human mus81-eme1 endonuclease. The Journal of Biological Chemistry. 278: 25172-8. PMID 12721304 DOI: 10.1074/Jbc.M302882200  0.541
2003 Henry-Mowatt J, Jackson D, Masson JY, Johnson PA, Clements PM, Benson FE, Thompson LH, Takeda S, West SC, Caldecott KW. XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes. Molecular Cell. 11: 1109-17. PMID 12718895 DOI: 10.1016/S1097-2765(03)00132-1  0.532
2003 Tarsounas M, Davies D, West SC. BRCA2-dependent and independent formation of RAD51 nuclear foci. Oncogene. 22: 1115-23. PMID 12606939 DOI: 10.1038/Sj.Onc.1206263  0.446
2003 Dai Y, Kysela B, Hanakahi LA, Manolis K, Riballo E, Stumm M, Harville TO, West SC, Oettinger MA, Jeggo PA. Nonhomologous end joining and V(D)J recombination require an additional factor. Proceedings of the National Academy of Sciences of the United States of America. 100: 2462-7. PMID 12604777 DOI: 10.1073/Pnas.0437964100  0.547
2003 West SC. Cross-links between Fanconi anaemia and BRCA2. Dna Repair. 2: 231-4. PMID 12531392 DOI: 10.1016/S1568-7864(02)00168-4  0.394
2002 Constantinou A, Chen XB, McGowan CH, West SC. Holliday junction resolution in human cells: two junction endonucleases with distinct substrate specificities. The Embo Journal. 21: 5577-85. PMID 12374758 DOI: 10.1093/Emboj/Cdf554  0.479
2002 Singleton MR, Wentzell LM, Liu Y, West SC, Wigley DB. Structure of the single-strand annealing domain of human RAD52 protein. Proceedings of the National Academy of Sciences of the United States of America. 99: 13492-7. PMID 12370410 DOI: 10.1073/Pnas.212449899  0.569
2002 Chappell C, Hanakahi LA, Karimi-Busheri F, Weinfeld M, West SC. Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining. The Embo Journal. 21: 2827-32. PMID 12032095 DOI: 10.1093/Emboj/21.11.2827  0.551
2002 Hanakahi LA, West SC. Specific interaction of IP6 with human Ku70/80, the DNA-binding subunit of DNA-PK. The Embo Journal. 21: 2038-44. PMID 11953323 DOI: 10.1093/Emboj/21.8.2038  0.553
2002 French CA, Masson JY, Griffin CS, O'Regan P, West SC, Thacker J. Role of mammalian RAD51L2 (RAD51C) in recombination and genetic stability. The Journal of Biological Chemistry. 277: 19322-30. PMID 11912211 DOI: 10.1074/Jbc.M201402200  0.554
2002 Liu Y, West SC. Distinct functions of BRCA1 and BRCA2 in double-strand break repair. Breast Cancer Research : Bcr. 4: 9-13. PMID 11879553 DOI: 10.1186/Bcr417  0.535
2001 Masson JY, Tarsounas MC, Stasiak AZ, Stasiak A, Shah R, McIlwraith MJ, Benson FE, West SC. Identification and purification of two distinct complexes containing the five RAD51 paralogs. Genes & Development. 15: 3296-307. PMID 11751635 DOI: 10.1101/Gad.947001  0.606
2001 McIlwraith MJ, Hall DR, Stasiak AZ, Stasiak A, Wigley DB, West SC. RadA protein from Archaeoglobus fulgidus forms rings, nucleoprotein filaments and catalyses homologous recombination. Nucleic Acids Research. 29: 4509-17. PMID 11713300 DOI: 10.1093/Nar/29.22.4509  0.629
2001 Van Dyck E, Stasiak AZ, Stasiak A, West SC. Visualization of recombination intermediates produced by RAD52-mediated single-strand annealing. Embo Reports. 2: 905-9. PMID 11571269 DOI: 10.1093/Embo-Reports/Kve201  0.629
2001 Masson JY, Stasiak AZ, Stasiak A, Benson FE, West SC. Complex formation by the human RAD51C and XRCC3 recombination repair proteins. Proceedings of the National Academy of Sciences of the United States of America. 98: 8440-6. PMID 11459987 DOI: 10.1073/Pnas.111005698  0.617
2001 Yu X, Jacobs SA, West SC, Ogawa T, Egelman EH. Domain structure and dynamics in the helical filaments formed by RecA and Rad51 on DNA. Proceedings of the National Academy of Sciences of the United States of America. 98: 8419-24. PMID 11459984 DOI: 10.1073/Pnas.111005398  0.474
2001 Constantinou A, Tarsounas M, Karow JK, Brosh RM, Bohr VA, Hickson ID, West SC. Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest. Embo Reports. 1: 80-4. PMID 11256630 DOI: 10.1093/Embo-Reports/Kvd004  0.523
2001 Davies AA, Masson JY, McIlwraith MJ, Stasiak AZ, Stasiak A, Venkitaraman AR, West SC. Role of BRCA2 in control of the RAD51 recombination and DNA repair protein. Molecular Cell. 7: 273-82. PMID 11239456 DOI: 10.1016/S1097-2765(01)00175-7  0.527
2001 Constantinou A, Davies AA, West SC. Branch migration and Holliday junction resolution catalyzed by activities from mammalian cells. Cell. 104: 259-68. PMID 11207366 DOI: 10.1016/S0092-8674(01)00210-0  0.59
2001 Masson JY, West SC. The Rad51 and Dmc1 recombinases: a non-identical twin relationship. Trends in Biochemical Sciences. 26: 131-6. PMID 11166572 DOI: 10.1016/S0968-0004(00)01742-4  0.552
2001 McIlwraith MJ, West SC. The efficiency of strand invasion by Escherichia coli RecA is dependent upon the length and polarity of ssDNA tails. Journal of Molecular Biology. 305: 23-31. PMID 11114244 DOI: 10.1006/Jmbi.2000.4268  0.547
2000 McIlwraith MJ, Van Dyck E, Masson JY, Stasiak AZ, Stasiak A, West SC. Reconstitution of the strand invasion step of double-strand break repair using human Rad51 Rad52 and RPA proteins. Journal of Molecular Biology. 304: 151-64. PMID 11080452 DOI: 10.1006/Jmbi.2000.4180  0.636
2000 Hanakahi LA, Bartlet-Jones M, Chappell C, Pappin D, West SC. Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair. Cell. 102: 721-9. PMID 11030616 DOI: 10.1016/S0092-8674(00)00061-1  0.611
2000 Arenas-Licea J, van Gool AJ, Keeley AJ, Davies A, West SC, Tsaneva IR. Functional interactions of Mycobacterium leprae RuvA with Escherichia coli RuvB and RuvC on holliday junctions. Journal of Molecular Biology. 301: 839-50. PMID 10966790 DOI: 10.1006/Jmbi.2000.4009  0.466
2000 Parsons CA, Baumann P, Van Dyck E, West SC. Precise binding of single-stranded DNA termini by human RAD52 protein Embo Journal. 19: 4175-4181. PMID 10921897 DOI: 10.1093/Emboj/19.15.4175  0.639
2000 Eggleston AK, West SC. Cleavage of holliday junctions by the Escherichia coli RuvABC complex. The Journal of Biological Chemistry. 275: 26467-76. PMID 10851230 DOI: 10.1074/Jbc.M001496200  0.8
2000 Karow JK, Constantinou A, Li JL, West SC, Hickson ID. The Bloom's syndrome gene product promotes branch migration of holliday junctions. Proceedings of the National Academy of Sciences of the United States of America. 97: 6504-8. PMID 10823897 DOI: 10.1073/Pnas.100448097  0.48
2000 Stasiak AZ, Larquet E, Stasiak A, Müller S, Engel A, Van Dyck E, West SC, Egelman EH. The human Rad52 protein exists as a heptameric ring. Current Biology : Cb. 10: 337-40. PMID 10744977 DOI: 10.1016/S0960-9822(00)00385-7  0.556
2000 George H, Kuraoka I, Nauman DA, Kobertz WR, Wood RD, West SC. RuvAB-mediated branch migration does not involve extensive DNA opening within the RuvB hexamer. Current Biology : Cb. 10: 103-6. PMID 10662672 DOI: 10.1016/S0960-9822(00)00296-7  0.641
2000 Yu VPCC, Koehler M, Steinlein C, Schmid M, Hanakahi LA, Gool AJv, West SC, Venkitaraman AR. Gross chromosomal rearrangements and genetic exchange between nonhomologous chromosomes following BRCA2 inactivation Genes & Development. 14: 1400-1406. DOI: 10.1101/Gad.14.11.1400  0.434
2000 West SC, Baillot A, Chappell C, Constantinou A, Davies A, Van Dyck E, Hanakahi L, Masson JY, McIlwraith M, Parsons CA, Tarsounas M. The repair of double-strand breaks in human cells Biochemical Society Transactions. 28: A101-A101. DOI: 10.1042/Bst028A101C  0.458
1999 Masson JY, Davies AA, Hajibagheri N, Van Dyck E, Benson FE, Stasiak AZ, Stasiak A, West SC. The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51. The Embo Journal. 18: 6552-60. PMID 10562567 DOI: 10.1093/Emboj/18.22.6552  0.637
1999 George H, Mézard C, Stasiak A, West SC. Helicase-defective RuvB(D113E) promotes RuvAB-mediated branch migration in vitro. Journal of Molecular Biology. 293: 505-19. PMID 10543946 DOI: 10.1006/Jmbi.1999.3187  0.634
1999 Passy SI, Yu X, Li Z, Radding CM, Masson JY, West SC, Egelman EH. Human Dmc1 protein binds DNA as an octameric ring Proceedings of the National Academy of Sciences of the United States of America. 96: 10684-10688. PMID 10485886 DOI: 10.1073/Pnas.96.19.10684  0.466
1999 Baumann P, West SC. Heteroduplex formation by human Rad51 protein: Effects of DNA end-structure, hRP-A and hRad52 Journal of Molecular Biology. 291: 363-374. PMID 10438626 DOI: 10.1006/Jmbi.1999.2954  0.647
1999 van Gool AJ, Hajibagheri NM, Stasiak A, West SC. Assembly of the Escherichia coli RuvABC resolvasome directs the orientation of holliday junction resolution. Genes & Development. 13: 1861-70. PMID 10421637 DOI: 10.1101/Gad.13.14.1861  0.572
1999 Van Dyck E, Stasiak AZ, Stasiak A, West SC. Binding of double-strand breaks in DNA by human Rad52 protein. Nature. 398: 728-31. PMID 10227297 DOI: 10.1038/19560  0.613
1999 Mézard C, George H, Davies AA, van Gool AJ, Zerbib D, Stasiak A, West SC. Escherichia coli RuvBL268S: a mutant RuvB protein that exhibits wild-type activities in vitro but confers a UV-sensitive ruv phenotype in vivo. Nucleic Acids Research. 27: 1275-82. PMID 9973614 DOI: 10.1093/Nar/27.5.1275  0.605
1999 Van Dyck E, Stasiak AZ, Stasiak A, West SC. Binding of double-strand breaks in DNA by human Rad52 protein Nature. 401: 403-403. DOI: 10.1038/43942  0.517
1998 Van Dyck E, Hajibagheri NM, Stasiak A, West SC. Visualisation of human rad52 protein and its complexes with hRad51 and DNA. Journal of Molecular Biology. 284: 1027-38. PMID 9837724 DOI: 10.1006/Jmbi.1998.2203  0.618
1998 Baumann P, West SC. DNA end-joining catalyzed by human cell-free extracts Proceedings of the National Academy of Sciences of the United States of America. 95: 14066-14070. PMID 9826654 DOI: 10.1073/Pnas.95.24.14066  0.584
1998 Zerbib D, Mézard C, George H, West SC. Coordinated actions of RuvABC in Holliday junction processing. Journal of Molecular Biology. 281: 621-30. PMID 9710535 DOI: 10.1006/Jmbi.1998.1959  0.552
1998 Baumann P, West SC. Role of the human RAD51 protein in homologous recombination and double- stranded-break repair Trends in Biochemical Sciences. 23: 247-251. PMID 9697414 DOI: 10.1016/S0968-0004(98)01232-8  0.619
1998 Hagan NF, Vincent SD, Ingleston SM, Sharples GJ, Bennett RJ, West SC, Lloyd RG. Sequence-specificity of Holliday junction resolution: identification of RuvC mutants defective in metal binding and target site recognition. Journal of Molecular Biology. 281: 17-29. PMID 9680472 DOI: 10.1006/Jmbi.1998.1934  0.7
1998 Davies AA, West SC. Formation of RuvABC-Holliday junction complexes in vitro. Current Biology : Cb. 8: 725-7. PMID 9637927 DOI: 10.1016/S0960-9822(98)70282-9  0.554
1998 van Gool AJ, Shah R, Mézard C, West SC. Functional interactions between the holliday junction resolvase and the branch migration motor of Escherichia coli. The Embo Journal. 17: 1838-45. PMID 9501105 DOI: 10.1093/Emboj/17.6.1838  0.576
1998 Benson FE, Baumann P, West SC. Synergistic actions of Rad51 and Rad52 in recombination and DNA repair. Nature. 391: 401-4. PMID 9450758 DOI: 10.1038/34937  0.637
1998 West SC. Processing of recombination intermediates by the RuvABC proteins. Annual Review of Genetics. 31: 213-44. PMID 9442895 DOI: 10.1146/Annurev.Genet.31.1.213  0.637
1997 Eggleston AK, West SC. Recombination initiation: easy as A, B, C, D... chi? Current Biology : Cb. 7: R745-9. PMID 9382825 DOI: 10.1016/S0960-9822(06)00394-0  0.758
1997 Barlow AL, Benson FE, West SC, Hultén MA. Distribution of the Rad51 recombinase in human and mouse spermatocytes. The Embo Journal. 16: 5207-15. PMID 9311981 DOI: 10.1093/Emboj/16.17.5207  0.418
1997 Baumann P, West SC. The human Rad51 protein: Polarity of strand transfer and stimulation by hRP-A Embo Journal. 16: 5198-5206. PMID 9311980 DOI: 10.1093/Emboj/16.17.5198  0.519
1997 Mézard C, Davies AA, Stasiak A, West SC. Biochemical properties of RuvBD113N: a mutation in helicase motif II of the RuvB hexamer affects DNA binding and ATPase activities. Journal of Molecular Biology. 271: 704-17. PMID 9299321 DOI: 10.1006/Jmbi.1997.1225  0.587
1997 Baumann P, Benson FE, Hajibagheri N, West SC. Purification of human Rad51 protein by selective spermidine precipitation. Mutation Research. 384: 65-72. PMID 9298115 DOI: 10.1016/S0921-8777(97)00028-1  0.407
1997 Stasiak A, West SC, Egelman EH. Sickle cell anemia research and a recombinant DNA technique. Science (New York, N.Y.). 277: 460-2. PMID 9254412 DOI: 10.1126/Science.277.5325.459C  0.451
1997 Zerbib D, Colloms SD, Sherratt DJ, West SC. Effect of DNA topology on Holliday junction resolution by Escherichia coli RuvC and bacteriophage T7 endonuclease I. Journal of Molecular Biology. 270: 663-73. PMID 9245595 DOI: 10.1006/Jmbi.1997.1157  0.604
1997 Eggleston AK, Mitchell AH, West SC. In vitro reconstitution of the late steps of genetic recombination in E. coli. Cell. 89: 607-17. PMID 9160752 DOI: 10.1016/S0092-8674(00)80242-1  0.724
1997 Shah R, Cosstick R, West SC. The RuvC protein dimer resolves Holliday junctions by a dual incision mechanism that involves base-specific contacts. The Embo Journal. 16: 1464-72. PMID 9135161 DOI: 10.1093/Emboj/16.6.1464  0.586
1997 Hiom K, Tsaneva IR, West SC. The directionality of RuvAB-mediated branch migration: in vitro studies with three-armed junctions. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 1: 443-51. PMID 9078376 DOI: 10.1046/J.1365-2443.1996.D01-253.X  0.538
1997 Yu X, West SC, Egelman EH. Structure and subunit composition of the RuvAB-Holliday junction complex. Journal of Molecular Biology. 266: 217-22. PMID 9047358 DOI: 10.1006/Jmbi.1996.0799  0.531
1997 West SC, Baumann P, Benson F, Davies A, Dyck Ev, Eggleston AK, George H, van Gool A, Kysela B, Mézard C, Parsons C, Stasiak A, Zerbib D. O VIII.1 Protein-directed molecular interactions in recombination and repair Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 379: S55. DOI: 10.1016/S0027-5107(97)82780-7  0.697
1996 Lehmann AR, Bridges BA, Hanawalt PC, Johnson RT, Kanaar R, Krokan HE, Kyrtopoulos S, Lambert B, Melton DW, Moustacchi E, Natarajan AT, Radman M, Sarasin A, Seeberg E, Smerdon MJ, ... ... West SC, et al. Workshop on processing of DNA damage. Mutation Research. 364: 245-70. PMID 8960136 DOI: 10.1016/S0921-8777(96)00037-7  0.446
1996 West SC. DNA helicases get physical. Nature. 384: 316-7. PMID 8934511 DOI: 10.1038/384316A0  0.52
1996 Baumann P, Benson FE, West SC. Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro. Cell. 87: 757-66. PMID 8929543 DOI: 10.1016/S0092-8674(00)81394-X  0.622
1996 Adams DE, West SC. Bypass of DNA heterologies during RuvAB-mediated three- and four-strand branch migration. Journal of Molecular Biology. 263: 582-96. PMID 8918940 DOI: 10.1006/Jmbi.1996.0600  0.642
1996 Bennett RJ, West SC. Resolution of Holliday junctions in genetic recombination: RuvC protein nicks DNA at the point of strand exchange. Proceedings of the National Academy of Sciences of the United States of America. 93: 12217-22. PMID 8901560 DOI: 10.1073/Pnas.93.22.12217  0.768
1996 Eggleston AK, West SC. Exchanging partners: recombination in E. coli. Trends in Genetics : Tig. 12: 20-6. PMID 8741856 DOI: 10.1016/0168-9525(96)81384-9  0.806
1996 West SC. DNA helicases: new breeds of translocating motors and molecular pumps. Cell. 86: 177-80. PMID 8706121 DOI: 10.1016/S0092-8674(00)80088-4  0.479
1996 Mitchell AH, West SC. Role of RuvA in branch migration reactions catalyzed by the RuvA and RuvB proteins of Escherichia coli Journal of Biological Chemistry. 271: 19497-19502. PMID 8702640 DOI: 10.1074/Jbc.271.32.19497  0.447
1996 West SC. The RuvABC proteins and Holliday junction processing in Escherichia coli. Journal of Bacteriology. 178: 1237-41. PMID 8631697 DOI: 10.1128/Jb.178.5.1237-1241.1996  0.398
1996 Adams DE, West SC. Relaxing and unwinding on Holliday: DNA helicase-mediated branch migration. Mutation Research. 337: 149-59. PMID 7491118 DOI: 10.1016/0921-8777(95)00031-E  0.566
1995 Shah R, Bennett RJ, West SC. Genetic recombination in E. coli: RuvC protein cleaves Holliday junctions at resolution hotspots in vitro. Cell. 79: 853-64. PMID 8001122 DOI: 10.1016/0092-8674(94)90074-4  0.677
1995 Hiom K, West SC. Branch migration during homologous recombination: assembly of a RuvAB-Holliday junction complex in vitro. Cell. 80: 787-93. PMID 7889572 DOI: 10.1016/0092-8674(95)90357-7  0.619
1995 Parsons CA, Stasiak A, Bennett RJ, West SC. Structure of a multisubunit complex that promotes DNA branch migration. Nature. 374: 375-8. PMID 7885479 DOI: 10.1038/374375A0  0.758
1995 West SC. Holliday junctions cleaved by Rad1? Nature. 373: 27-8. PMID 7800034 DOI: 10.1038/373027A0  0.394
1995 Bennett RJ, West SC. RuvC protein resolves Holliday junctions via cleavage of the continuous (noncrossover) strands. Proceedings of the National Academy of Sciences of the United States of America. 92: 5635-9. PMID 7777562 DOI: 10.1073/Pnas.92.12.5635  0.77
1995 West SC. Formation, translocation and resolution of Holliday junctions during homologous genetic recombination. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 347: 21-5. PMID 7746849 DOI: 10.1098/Rstb.1995.0004  0.526
1995 Adams DE, West SC. Unwinding of closed circular DNA by the Escherichia coli RuvA and RuvB recombination/repair proteins. Journal of Molecular Biology. 247: 404-17. PMID 7714897 DOI: 10.1006/Jmbi.1995.0149  0.641
1995 Bennett RJ, West SC. Structural analysis of the RuvC-Holliday junction complex reveals an unfolded junction. Journal of Molecular Biology. 252: 213-26. PMID 7674302 DOI: 10.1006/Jmbi.1995.0489  0.67
1995 Davies AA, Friedberg EC, Tomkinson AE, Wood RD, West SC. Role of the Rad1 and Rad10 proteins in nucleotide excision repair and recombination. The Journal of Biological Chemistry. 270: 24638-41. PMID 7559571 DOI: 10.1074/Jbc.270.42.24638  0.671
1995 Hiom K, West SC. Characterisation of RuvAB-Holliday junction complexes by glycerol gradient sedimentation. Nucleic Acids Research. 23: 3621-6. PMID 7478987 DOI: 10.1093/Nar/23.18.3621  0.514
1995 Parsons CA, Stasiak A, West SC. The E.coli RuvAB proteins branch migrate Holliday junctions through heterologous DNA sequences in a reaction facilitated by SSB. The Embo Journal. 14: 5736-5744. DOI: 10.1002/J.1460-2075.1995.Tb00260.X  0.656
1994 West SC. The processing of recombination intermediates: mechanistic insights from studies of bacterial proteins. Cell. 76: 9-15. PMID 8287483 DOI: 10.1016/0092-8674(94)90168-6  0.645
1994 Müller B, West SC. Processing of Holliday junctions by the Escherichia coli RuvA, RuvB, RuvC and RecG proteins. Experientia. 50: 216-22. PMID 8143795 DOI: 10.1007/Bf01924004  0.532
1994 O'Donovan A, Davies AA, Moggs JG, West SC, Wood RD. XPG endonuclease makes the 3' incision in human DNA nucleotide excision repair. Nature. 371: 432-5. PMID 8090225 DOI: 10.1038/371432A0  0.607
1994 Stasiak A, Tsaneva IR, West SC, Benson CJ, Yu X, Egelman EH. The Escherichia coli RuvB branch migration protein forms double hexameric rings around DNA. Proceedings of the National Academy of Sciences of the United States of America. 91: 7618-22. PMID 8052630 DOI: 10.1073/Pnas.91.16.7618  0.646
1994 Shah R, Bennett RJ, West SC. Activation of RuvC Holliday junction resolvase in vitro Nucleic Acids Research. 22: 2490-2497. PMID 8041610 DOI: 10.1093/Nar/22.13.2490  0.685
1994 Dunderdale HJ, West SC. Recombination genes and proteins. Current Opinion in Genetics & Development. 4: 221-8. PMID 8032199 DOI: 10.1016/S0959-437X(05)80048-6  0.517
1994 Müller B, West SC. An assay for in vitro recombination between duplex DNA molecules. Methods in Molecular Biology (Clifton, N.J.). 30: 413-23. PMID 8004213 DOI: 10.1385/0-89603-256-6:413  0.547
1994 Adams DE, Tsaneva IR, West SC. Dissociation of RecA filaments from duplex DNA by the RuvA and RuvB DNA repair proteins. Proceedings of the National Academy of Sciences of the United States of America. 91: 9901-5. PMID 7937914 DOI: 10.1073/Pnas.91.21.9901  0.653
1994 Mitchell AH, West SC. Hexameric rings of Escherichia coli RuvB protein: Cooperative assembly, processivity and ATPase activity Journal of Molecular Biology. 243: 208-215. PMID 7932751 DOI: 10.1006/Jmbi.1994.1648  0.577
1994 Tsaneva IR, West SC. Targeted versus non-targeted DNA helicase activity of the RuvA and RuvB proteins of Escherichia coli Journal of Biological Chemistry. 269: 26552-26558. DOI: 10.1016/s0021-9258(18)47230-4  0.383
1994 Benson F, West S. Substrate specificity of the Escherichia coli RuvC protein. Resolution of three- and four-stranded recombination intermediates. Journal of Biological Chemistry. 269: 5195-5201. DOI: 10.1016/s0021-9258(17)37674-3  0.392
1994 Benson F, Stasiak A, West S. Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA. The Embo Journal. 13: 5764-5771. DOI: 10.1002/J.1460-2075.1994.Tb06914.X  0.632
1993 Tsaneva IR, Müller B, West SC. RuvA and RuvB proteins of Escherichia coli exhibit DNA helicase activity in vitro. Proceedings of the National Academy of Sciences of the United States of America. 90: 1315-9. PMID 8433990 DOI: 10.1073/Pnas.90.4.1315  0.65
1993 Bennett RJ, Dunderdale HJ, West SC. Resolution of Holliday junctions by RuvC resolvase: cleavage specificity and DNA distortion. Cell. 74: 1021-31. PMID 8402879 DOI: 10.1016/0092-8674(93)90724-5  0.773
1993 Parsons CA, West SC. Formation of a RuvAB-Holliday junction complex in vitro. Journal of Molecular Biology. 232: 397-405. PMID 8393934 DOI: 10.1006/Jmbi.1993.1399  0.563
1993 West SC, Tsaneva IR, Hiom K, Benson FE. Late steps in genetic recombination: branch migration and Holliday junction resolution by RuvA, RuvB, and RuvC proteins. Cold Spring Harbor Symposia On Quantitative Biology. 58: 525-31. PMID 7956066 DOI: 10.1101/Sqb.1993.058.01.059  0.409
1992 West SC. Three-stranded DNA helices as intermediates in genetic recombination. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 13: 37-8. PMID 1772408 DOI: 10.1002/Bies.950130107  0.56
1992 Tsaneva IR, Müller B, West SC. ATP-dependent branch migration of Holliday junctions promoted by the RuvA and RuvB proteins of E. coli. Cell. 69: 1171-80. PMID 1617728 DOI: 10.1016/0092-8674(92)90638-S  0.624
1992 Parsons CA, Tsaneva I, Lloyd RG, West SC. Interaction of Escherichia coli RuvA and RuvB proteins with synthetic Holliday junctions. Proceedings of the National Academy of Sciences of the United States of America. 89: 5452-6. PMID 1608954 DOI: 10.1073/Pnas.89.12.5452  0.633
1992 West SC. Enzymes and molecular mechanisms of genetic recombination. Annual Review of Biochemistry. 61: 603-40. PMID 1497320 DOI: 10.1146/Annurev.Bi.61.070192.003131  0.616
1992 Tsaneva IR, Illing G, Lloyd RG, West SC. Purification and properties of the RuvA and RuvB proteins of Escherichia coli. Molecular & General Genetics : Mgg. 235: 1-10. PMID 1435721 DOI: 10.1007/Bf00286175  0.527
1992 West SC, Connolly B. Biological roles of the Escherichia coli RuvA, RuvB and RuvC proteins revealed. Molecular Microbiology. 6: 2755-9. PMID 1435254 DOI: 10.1111/J.1365-2958.1992.Tb01454.X  0.635
1992 Müller B, Burdett I, West S. Unusual stability of recombination intermediates made by Escherichia coli RecA protein. The Embo Journal. 11: 2685-2693. DOI: 10.1002/J.1460-2075.1992.Tb05334.X  0.587
1991 Connolly B, Parsons CA, Benson FE, Dunderdale HJ, Sharples GJ, Lloyd RG, West SC. Resolution of Holliday junctions in vitro requires the Escherichia coli ruvC gene product. Proceedings of the National Academy of Sciences of the United States of America. 88: 6063-7. PMID 1829835 DOI: 10.1073/Pnas.88.14.6063  0.554
1991 Dunderdale HJ, Benson FE, Parsons CA, Sharples GJ, Lloyd RG, West SC. Formation and resolution of recombination intermediates by E. coli RecA and RuvC proteins. Nature. 354: 506-10. PMID 1758493 DOI: 10.1038/354506A0  0.638
1990 Müller B, Jones C, West SC. T7 endonuclease I resolves Holliday junctions formed in vitro by RecA protein. Nucleic Acids Research. 18: 5633-6. PMID 2216756 DOI: 10.1093/Nar/18.19.5633  0.551
1990 West SC. Processing of recombination intermediates in vitro. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 12: 151-4. PMID 2185746 DOI: 10.1002/Bies.950120402  0.559
1990 Parsons CA, West SC. Specificity of binding to four-way junctions in DNA by bacteriophage T7 endonuclease I. Nucleic Acids Research. 18: 4377-84. PMID 2167465 DOI: 10.1093/Nar/18.15.4377  0.514
1990 Picksley SM, Parsons CA, Kemper B, West SC. Cleavage specificity of bacteriophage T4 endonuclease VII and bacteriophage T7 endonuclease I on synthetic branch migratable Holliday junctions. Journal of Molecular Biology. 212: 723-35. PMID 2158565 DOI: 10.1016/0022-2836(90)90233-C  0.486
1990 Connolly B, West SC. Genetic recombination in Escherichia coli: Holliday junctions made by RecA protein are resolved by fractionated cell-free extracts. Proceedings of the National Academy of Sciences of the United States of America. 87: 8476-80. PMID 2146685 DOI: 10.1073/Pnas.87.21.8476  0.588
1990 Müller B, Jones C, Kemper B, West SC. Enzymatic formation and resolution of Holliday junctions in vitro. Cell. 60: 329-36. PMID 2137030 DOI: 10.1016/0092-8674(90)90747-3  0.556
1990 Parsons CA, Kemper B, West SC. Interaction of a four-way junction in DNA with T4 endonuclease VII. Journal of Biological Chemistry. 265: 9285-9289. DOI: 10.1016/s0021-9258(19)38845-3  0.378
1990 Conley EC, West SC. Underwinding of DNA associated with duplex-duplex pairing by RecA protein. Journal of Biological Chemistry. 265: 10156-10163. DOI: 10.1016/s0021-9258(19)38793-9  0.512
1990 Elborough KM, West SC. Resolution of synthetic Holliday junctions in DNA by an endonuclease activity from calf thymus. The Embo Journal. 9: 2931-2936. DOI: 10.1002/J.1460-2075.1990.Tb07484.X  0.592
1989 West SC. Protein-DNA interactions in genetic recombination. Trends in Genetics : Tig. 4: 8-13. PMID 3070851 DOI: 10.1016/0168-9525(88)90121-7  0.616
1989 Conley EC, West SC. Homologous pairing and the formation of nascent synaptic intermediates between regions of duplex DNA by RecA protein Cell. 56: 987-995. PMID 2647306 DOI: 10.1016/0092-8674(89)90632-6  0.616
1989 Parsons CA, Murchie AI, Lilley DM, West SC. Resolution of model Holliday junctions by yeast endonuclease: effect of DNA structure and sequence. The Embo Journal. 8: 239-246. DOI: 10.1002/J.1460-2075.1989.Tb03369.X  0.511
1988 Elborough KM, West SC. Specific binding of cruciform DNA structures by a protein from human extracts. Nucleic Acids Research. 16: 3603-16. PMID 3375068 DOI: 10.1093/Nar/16.9.3603  0.572
1988 Parsons CA, West SC. Resolution of model Holliday junctions by yeast endonuclease is dependent upon homologous DNA sequences. Cell. 52: 621-9. PMID 3277721 DOI: 10.1016/0092-8674(88)90474-6  0.565
1988 Hahn TR, West S, Howard-Flanders P. RecA-mediated strand exchange reactions between duplex DNA molecules containing damaged bases, deletions, and insertions. Journal of Biological Chemistry. 263: 7431-7436. DOI: 10.1016/s0021-9258(18)68660-0  0.46
1987 West SC, Parsons CA, Picksley SM. Purification and properties of a nuclease from Saccharomyces cerevisiae that cleaves DNA at cruciform junctions. Journal of Biological Chemistry. 262: 12752-12758. DOI: 10.1016/s0021-9258(18)45270-2  0.494
1985 Howard-Flanders P, West SC, Rusche JR, Egelman EH. Molecular mechanisms of general genetic recombination: the DNA-binding sites of RecA protein. Cold Spring Harbor Symposia On Quantitative Biology. 49: 571-80. PMID 6397312 DOI: 10.1101/Sqb.1984.049.01.064  0.531
1985 West SC, Körner A. Cleavage of cruciform DNA structures by an activity from Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 82: 6445-9. PMID 3901001 DOI: 10.1073/Pnas.82.19.6445  0.605
1984 West SC, Little JW. P. mirabilis RecA protein catalyses cleavage of E. coli LexA protein and the lambda repressor in vitro. Molecular & General Genetics : Mgg. 194: 111-3. PMID 6374373 DOI: 10.1007/Bf00383505  0.442
1984 West SC, Howard-Flanders P. Duplex-duplex interactions catalyzed by RecA protein allow strand exchanges to pass double-strand breaks in DNA. Cell. 37: 683-91. PMID 6327083 DOI: 10.1016/0092-8674(84)90401-X  0.637
1984 Howard-Flanders P, West SC, Stasiak A. Role of RecA protein spiral filaments in genetic recombination. Nature. 309: 215-9. PMID 6325943 DOI: 10.1038/309215A0  0.425
1983 West SC, Countryman JK, Howard-Flanders P. Enzymatic formation of biparental figure-eight molecules from plasmid DNA and their resolution in E. coli. Cell. 32: 817-29. PMID 6339073 DOI: 10.1016/0092-8674(83)90068-5  0.6
1983 West SC, Cassuto E, Howard-Flanders P. Postreplication repair in E. coli: strand exchange reactions of gapped DNA by RecA protein. Molecular & General Genetics : Mgg. 187: 209-17. PMID 6217396 DOI: 10.1007/Bf00331119  0.612
1983 West SC, Countryman JK, Howard-Flanders P. Purification and properties of the recA protein of Proteus mirabilis. Comparison with Escherichia coli recA protein; specificity of interaction with single strand binding protein. Journal of Biological Chemistry. 258: 4648-4654. DOI: 10.1016/s0021-9258(18)32673-5  0.335
1982 West SC, Cassuto E, Howard-Flanders P. Mechanism of E. coli RecA protein directed strand exchanges in post-replication repair of DNA. Nature. 294: 659-62. PMID 7031482 DOI: 10.1038/294659A0  0.664
1982 Cassuto E, West SC, Podell J, Howard-Flanders P. Genetic recombination: recA protein promotes homologous pairing between duplex DNA molecules without strand unwinding. Nucleic Acids Research. 9: 4201-10. PMID 7029464 DOI: 10.1093/Nar/9.16.4201  0.62
1982 West SC, Cassuto E, Howard-Flanders P. Heteroduplex formation by recA protein: polarity of strand exchanges. Proceedings of the National Academy of Sciences of the United States of America. 78: 6149-53. PMID 6273854 DOI: 10.1073/Pnas.78.10.6149  0.594
1982 West SC, Cassuto E, Howard-Flanders P. Role of SSB protein in RecA promoted branch migration reactions. Molecular & General Genetics : Mgg. 186: 333-8. PMID 6214697 DOI: 10.1007/Bf00729451  0.611
1982 Cassuto E, West S, Howard-Flanders P. Can recA protein promote homologous pairing between duplex regions of DNA? The Embo Journal. 1: 821-825. DOI: 10.1002/J.1460-2075.1982.Tb01254.X  0.56
1981 West SC, Cassuto E, Howard-Flanders P. recA protein promotes homologous-pairing and strand-exchange reactions between duplex DNA molecules. Proceedings of the National Academy of Sciences of the United States of America. 78: 2100-4. PMID 6941272 DOI: 10.1073/Pnas.78.4.2100  0.623
1981 West SC, Cassuto E, Howard-Flanders P. Homologous pairing can occur before DNA strand separation in general genetic recombination. Nature. 290: 29-33. PMID 6451807 DOI: 10.1038/290029A0  0.617
1981 Cassuto E, West SC, Mursalim J, Conlon S, Howard-Flanders P. Initiation of genetic recombination: homologous pairing between duplex DNA molecules promoted by recA protein. Proceedings of the National Academy of Sciences of the United States of America. 77: 3962-6. PMID 6449004 DOI: 10.1073/Pnas.77.7.3962  0.607
1980 West SC, Cassuto E, Mursalim J, Howard-Flanders P. Recognition of duplex DNA containing single-stranded regions by recA protein. Proceedings of the National Academy of Sciences of the United States of America. 77: 2569-73. PMID 6446716 DOI: 10.1073/Pnas.77.5.2569  0.637
1980 Emmerson PT, Northrop FD, Walker JE, West SC. Amino terminal sequence of the recA protein of Escherichia coli. Febs Letters. 106: 349-51. PMID 387448 DOI: 10.1016/0014-5793(79)80530-X  0.355
1978 Emmerson PT, West SC. Identification of protein X of Escherichia coli as the recA+/tif+ gene product. Molecular & General Genetics : Mgg. 155: 77-85. PMID 337120 DOI: 10.1007/Bf00268563  0.35
1978 Emmerson PT, West SC. INDUCTION AND REPRESSION OF THE recA GENE OF ESCHERICHIA COLI Dna Repair Mechanisms. 367-370. DOI: 10.1016/B978-0-12-322650-1.50069-2  0.455
1977 West SC, Emmerson PT. Induction of protein synthesis in Escherichia coli following UV- or gamma-irradiation, mitomycin C treatment or tif Expression. Molecular & General Genetics : Mgg. 151: 57-67. PMID 325368 DOI: 10.1007/Bf00446913  0.474
1975 West SC, Powell KA, Emmerson PT. recA+-dependent inactivation of the lambda repressor in Escherichia coli lysogens by γ-radiation and by tif expression Mgg Molecular &Amp; General Genetics. 141: 1-8. PMID 765722 DOI: 10.1007/Bf00332374  0.419
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