Bilha Fischer - Publications

Affiliations: 
1992-1993 Bar-Ilan University, Jerusalem, Jerusalem District, Israel 

93 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Salameh H, Afri M, Gottlieb HE, Fischer B. β-Cyanuryl Ribose, β-Barbituryl Ribose, and 6-Azauridine as Uridine Mimetics. Acs Omega. 5: 31314-31322. PMID 33324842 DOI: 10.1021/acsomega.0c04788  0.56
2020 Nassir M, Balaom L, Fischer B. Addressing regio- and stereo-specificity challenges in the synthesis of nucleoside 2',3'-cyclic monophosphate analogs - a rapid and facile synthesis of nucleoside-2',3'-,-phosphoro-thioate or -selenoate, and elucidation of the origin of the rare specificity. Chemical Communications (Cambridge, England). PMID 32870217 DOI: 10.1039/D0Cc02886J  0.32
2019 Nassir M, Mirza S, Arad U, Lee S, Rafehi M, Yaw Attah I, Renn C, Zimmermann H, Pelletier J, Sévigny J, Müller CE, Fischer B. Adenine-(methoxy)-ethoxy-P-dithio-triphosphate inhibits pathologic calcium pyrophosphate deposition in osteoarthritic human chondrocytes. Organic & Biomolecular Chemistry. PMID 31720670 DOI: 10.1039/C9Ob02199J  0.32
2019 Nassir M, Pelletier J, Arad U, Arguin G, Khazanov N, Gendron FP, Sévigny J, Senderowitz H, Fischer B. Structure-activity relationship study of NPP1 inhibitors based on uracil-N1-(methoxy)ethyl-β-phosphate scaffold. European Journal of Medicinal Chemistry. 184: 111754. PMID 31610377 DOI: 10.1016/J.Ejmech.2019.111754  0.32
2019 Pariente Cohen N, Lo Presti E, Dell'Acqua S, Jantz T, Shimon LJW, Levi Hevroni B, Levy N, Nassir M, Elbaz L, Casella L, Fischer B. Correction to Aminomethylene-Phosphonate Analogue as a Cu(II) Chelator: Characterization and Application as an Inhibitor of Oxidation Induced by Cu(II)-Prion Peptide Complex. Inorganic Chemistry. PMID 31479250 DOI: 10.1021/Acs.Inorgchem.9B02110  0.4
2019 Nassir M, Arad U, Lee SY, Journo S, Renn SMC, Zimmermann H, Pelletier J, Sévigny J, Müller CE, Fischer B. Correction to: Identification of adenine-N9-(methoxy)ethyl-β-bisphosphonate as NPP1 inhibitor attenuates NPPase activity in human osteoarthritic chondrocytes. Purinergic Signalling. PMID 31327117 DOI: 10.1007/s11302-019-09671-4  0.32
2019 Pariente Cohen N, Lo Presti E, Dell'Acqua S, Jantz T, Shimon LJW, Levy N, Nassir M, Elbaz L, Casella L, Fischer B. Aminomethylene-Phosphonate Analogue as a Cu(II) Chelator: Characterization and Application as an Inhibitor of Oxidation Induced by the Cu(II)-Prion Peptide Complex. Inorganic Chemistry. PMID 31247811 DOI: 10.1021/Acs.Inorgchem.9B00287  0.32
2019 Nassir M, Arad U, Lee SY, Journo S, Mirza S, Renn C, Müller CE, Fischer B. Identification of adenine-N9-(methoxy)ethyl-β-bisphosphonate as NPP1 inhibitor attenuating undesired NPPase activity in human osteoarthritic chondrocytes. Purinergic Signalling. PMID 31025169 DOI: 10.1007/S11302-019-09649-2  0.32
2018 Jacob TF, Singh V, Dixit M, Ginsburg-Shmuel T, Fonseca B, Pintor J, Youdim MBH, Major DT, Weinreb O, Fischer B. A promising drug candidate for the treatment of glaucoma based on a P2Y6-receptor agonist. Purinergic Signalling. PMID 30019187 DOI: 10.1007/S11302-018-9614-7  0.96
2018 Danino O, Svetitsky S, Kenigsberg S, Levin A, Journo S, Gold A, Drexler M, Snir N, Elkayam O, Fischer B, Arad U. Inhibition of nucleotide pyrophosphatase/phosphodiesterase 1: implications for developing a calcium pyrophosphate deposition disease modifying drug. Rheumatology (Oxford, England). PMID 29688536 DOI: 10.1093/Rheumatology/Key092  0.4
2018 Zelikman V, Pelletier J, Simhaev L, Sela A, Gendron FP, Arguin G, Senderowitz H, Sévigny J, Fischer B. Highly Selective and Potent Ecto-nucleotide pyro¬phosphatase-1 (NPP1) Inhibitors Based on Uridine-5'-Pα,α-dithiophosphate Analogues. Journal of Medicinal Chemistry. PMID 29681152 DOI: 10.1021/Acs.Jmedchem.7B01906  0.32
2017 Segal-Gavish H, Danino O, Barhum Y, Ben-Zur T, Shai E, Varon D, Offen D, Fischer B. A Multifunctional Biocompatible Drug Candidate is Highly Effective in Delaying Pathological Signs of Alzheimer's Disease in 5XFAD Mice. Journal of Alzheimer's Disease : Jad. PMID 28453480 DOI: 10.3233/Jad-161236  0.4
2017 Hevroni BL, Jantz T, Gottlieb HE, Fischer B. (Aminomethylene)phosphonate Analogues as ZnII Chelators: Synthesis and Characterization European Journal of Inorganic Chemistry. 2017: 2955-2967. DOI: 10.1002/Ejic.201700210  0.64
2016 Hevroni BL, Major DT, Dixit M, Mhashal AR, Das S, Fischer B. Nucleoside-2',3'/3',5'-bis(thio)phosphate antioxidants are also capable of disassembly of amyloid beta42-Zn(ii)/Cu(ii) aggregates via Zn(ii)/Cu(ii)-chelation. Organic & Biomolecular Chemistry. PMID 27109038 DOI: 10.1039/C6Ob00613B  0.72
2015 Meltzer D, Gottlieb HE, Amir A, Shimon LJ, Fischer B. Novel crown-ether-methylenediphosphonotetrathioate hybrids as Zn(ii) chelators. Dalton Transactions (Cambridge, England : 2003). PMID 26592926 DOI: 10.1039/C5Dt03935E  0.72
2015 Azran S, Danino O, Förster D, Kenigsberg S, Reiser G, Dixit M, Singh V, Major DT, Fischer B. Identification of Highly Promising Antioxidants/Neuroprotectants Based on Nucleoside 5'-Phosphorothioate Scaffold. Synthesis, Activity, and Mechanisms of Action. Journal of Medicinal Chemistry. PMID 26447940 DOI: 10.1021/Acs.Jmedchem.5B00575  0.72
2015 Meltzer D, Ethan O, Arguin G, Nadel Y, Danino O, Lecka J, Sévigny J, Gendron FP, Fischer B. Synthesis and structure-activity relationship of uracil nucleotide derivatives towards the identification of human P2Y6 receptor antagonists. Bioorganic & Medicinal Chemistry. 23: 5764-73. PMID 26233801 DOI: 10.1016/J.Bmc.2015.07.004  0.4
2015 Sayer AH, Blum E, Major DT, Vardi-Kilshtain A, Levi Hevroni B, Fischer B. Adenosine/guanosine-3',5'-bis-phosphates as biocompatible and selective Zn2+-ion chelators. Characterization and comparison with adenosine/guanosine-5'-di-phosphate. Dalton Transactions (Cambridge, England : 2003). 44: 7305-17. PMID 25797179 DOI: 10.1039/C5Dt00080G  0.72
2015 Danino O, Grossman S, Fischer B. ATP-γ-S-(α,β-CH2) protects against oxidative stress and amyloid beta toxicity in neuronal culture. Biochemical and Biophysical Research Communications. 460: 446-50. PMID 25796332 DOI: 10.1016/J.Bbrc.2015.03.053  0.72
2015 Meltzer D, Ethan O, Arguin G, Nadel Y, Danino O, Lecka J, Sévigny J, Gendron FP, Fischer B. Synthesis and structure-activity relationship of uracil nucleotide derivatives towards the identification of human P2Y6 receptor antagonists Bioorganic and Medicinal Chemistry. DOI: 10.1016/j.bmc.2015.07.004  0.72
2014 Kovaliov M, Wachtel C, Yavin E, Fischer B. Synthesis and evaluation of a photoresponsive quencher for fluorescent hybridization probes. Organic & Biomolecular Chemistry. 12: 7844-58. PMID 25177827 DOI: 10.1039/C4Ob01185F  0.72
2014 Amir A, Ezra A, Shimon LJ, Fischer B. Novel Cu(I)-selective chelators based on a bis(phosphorothioyl)amide scaffold. Inorganic Chemistry. 53: 7901-8. PMID 25033439 DOI: 10.1021/Ic500465Z  0.72
2014 Kovaliov M, Weitman M, Major DT, Fischer B. Phenyl-imidazolo-cytidine analogues: structure-photophysical activity relationship and ability to detect single DNA mismatch. The Journal of Organic Chemistry. 79: 7051-62. PMID 24992467 DOI: 10.1021/Jo5011944  0.72
2014 Gillerman I, Lecka J, Simhaev L, Munkonda MN, Fausther M, Martín-Satué M, Senderowitz H, Sévigny J, Fischer B. 2-Hexylthio-β,γ-CH2-ATP is an effective and selective NTPDase2 inhibitor. Journal of Medicinal Chemistry. 57: 5919-34. PMID 24972256 DOI: 10.1021/Jm401933C  0.72
2014 Haas M, Ginsburg-Shmuel T, Fischer B, Reiser G. 5-OMe-uridine-5'-O-(α-boranodiphosphate), a novel nucleotide derivative highly active at the human P2Y(6) receptor protects against death-receptor mediated glial apoptosis. Neuroscience Letters. 578: 80-4. PMID 24970757 DOI: 10.1016/J.Neulet.2014.06.030  0.72
2014 Nadel Y, Lecka J, Gilad Y, Ben-David G, Förster D, Reiser G, Kenigsberg S, Camden J, Weisman GA, Senderowitz H, Sévigny J, Fischer B. Highly potent and selective ectonucleotide pyrophosphatase/phosphodiesterase I inhibitors based on an adenosine 5'-(α or γ)-thio-(α,β- or β,γ)-methylenetriphosphate scaffold. Journal of Medicinal Chemistry. 57: 4677-91. PMID 24846781 DOI: 10.1021/Jm500196C  0.72
2014 Zilbershtein-Shklanovsky L, Kafri P, Shav-Tal Y, Yavin E, Fischer B. Development of fluorescent double-strand probes labeled with 8-(p-CF3-cinnamyl)-adenosine for the detection of cyclin D1 breast cancer marker. European Journal of Medicinal Chemistry. 79: 77-88. PMID 24727242 DOI: 10.1016/J.Ejmech.2014.03.081  0.72
2014 Kovaliov M, Segal M, Kafri P, Yavin E, Shav-Tal Y, Fischer B. Detection of cyclin D1 mRNA by hybridization sensitive NIC-oligonucleotide probe. Bioorganic & Medicinal Chemistry. 22: 2613-21. PMID 24726303 DOI: 10.1016/J.Bmc.2014.03.033  0.72
2014 Danino O, Giladi N, Grossman S, Fischer B. Nucleoside 5'-phosphorothioate derivatives are highly effective neuroprotectants. Biochemical Pharmacology. 88: 384-92. PMID 24548458 DOI: 10.1016/J.Bcp.2014.02.001  0.72
2014 Hevroni BL, Sayer AH, Blum E, Fischer B. Nucleoside-2',3'/3',5'-bis(thio)phosphate analogues are promising antioxidants acting mainly via Cu+/Fe2+ ion chelation. Inorganic Chemistry. 53: 1594-605. PMID 24410662 DOI: 10.1021/Ic402671Q  0.72
2013 Zilbershtein-Shklanovsky L, Weitman M, Major DT, Fischer B. Rules for the design of highly fluorescent nucleoside probes: 8-(substituted cinnamyl)-adenosine analogues. The Journal of Organic Chemistry. 78: 11999-2008. PMID 24206423 DOI: 10.1021/Jo402050X  0.72
2013 Lecka J, Ben-David G, Simhaev L, Eliahu S, Oscar J, Luyindula P, Pelletier J, Fischer B, Senderowitz H, Sévigny J. Nonhydrolyzable ATP analogues as selective inhibitors of human NPP1: a combined computational/experimental study. Journal of Medicinal Chemistry. 56: 8308-20. PMID 24083941 DOI: 10.1021/Jm400918S  0.32
2013 Sayer AH, Itzhakov Y, Stern N, Nadel Y, Fischer B. Characterization of complexes of nucleoside-5'-phosphorothioate analogues with zinc ions. Inorganic Chemistry. 52: 10886-96. PMID 24050595 DOI: 10.1021/Ic400878K  0.56
2013 Haas M, Ben-Moshe I, Fischer B, Reiser G. Sp-2-propylthio-ATP-α-B and Sp-2-propylthio-ATP-α-B,β-γ-dichloromethylene are novel potent and specific agonists of the human P2Y₁₁ receptor. Biochemical Pharmacology. 86: 645-55. PMID 23810430 DOI: 10.1016/J.Bcp.2013.06.013  0.72
2013 Azran S, Förster D, Danino O, Nadel Y, Reiser G, Fischer B. Highly efficient biocompatible neuroprotectants with dual activity as antioxidants and P2Y receptor agonists. Journal of Medicinal Chemistry. 56: 4938-52. PMID 23751098 DOI: 10.1021/Jm400197M  0.72
2013 Danino O, Grossman S, Fischer B. Nucleoside 5'-phosphorothioate derivatives as oxidative stress protectants in PC12 cells. Nucleosides, Nucleotides & Nucleic Acids. 32: 333-53. PMID 23742060 DOI: 10.1080/15257770.2013.789107  0.72
2013 Segal M, Yavin E, Kafri P, Shav-Tal Y, Fischer B. Detection of mRNA of the cyclin D1 breast cancer marker by a novel duplex-DNA probe. Journal of Medicinal Chemistry. 56: 4860-9. PMID 23688195 DOI: 10.1021/Jm301838Y  0.72
2013 Amir A, Sayer AH, Ezra A, Fischer B. Methylenediphosphonotetrathioate: synthesis, characterization, and chemical properties. Inorganic Chemistry. 52: 3133-40. PMID 23452087 DOI: 10.1021/Ic3026057  0.4
2013 Amir A, Sayer AH, Zagalsky R, Shimon LJ, Fischer B. O,O'-Diester methylenediphosphonotetrathioate: synthesis, characterization, and potential applications. The Journal of Organic Chemistry. 78: 270-7. PMID 23205517 DOI: 10.1021/Jo301786M  0.4
2013 Kovaliov M, Segal M, Fischer B. Fluorescent p-substituted-phenyl-imidazolo-cytidine analogues Tetrahedron. 69: 3698-3705. DOI: 10.1016/J.Tet.2013.03.005  0.72
2012 Ginsburg-Shmuel T, Haas M, Grbic D, Arguin G, Nadel Y, Gendron FP, Reiser G, Fischer B. UDP made a highly promising stable, potent, and selective P2Y6-receptor agonist upon introduction of a boranophosphate moiety. Bioorganic & Medicinal Chemistry. 20: 5483-95. PMID 22901672 DOI: 10.1016/J.Bmc.2012.07.042  0.72
2012 Yelovitch S, Barr HM, Camden J, Weisman GA, Shai E, Varon D, Fischer B. Identification of a promising drug candidate for the treatment of type 2 diabetes based on a P2Y(1) receptor agonist. Journal of Medicinal Chemistry. 55: 7623-35. PMID 22873688 DOI: 10.1021/Jm3006355  0.72
2012 Amir A, Shmuel E, Zagalsky R, Sayer AH, Nadel Y, Fischer B. Nucleoside-5'-phosphorothioate analogues are biocompatible antioxidants dissolving efficiently amyloid beta-metal ion aggregates. Dalton Transactions (Cambridge, England : 2003). 41: 8539-49. PMID 22652964 DOI: 10.1039/C2Dt30631J  0.4
2012 Stern N, Major DT, Gottlieb HE, Weizman D, Sayer AH, Blum E, Fischer B. Studies of Mg2+/Ca2+ complexes of naturally occurring dinucleotides: potentiometric titrations, NMR, and molecular dynamics. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 17: 861-79. PMID 22592972 DOI: 10.1007/S00775-012-0903-2  0.72
2012 Yelovitch S, Camden J, Weisman GA, Fischer B. Boranophosphate isoster controls P2Y-receptor subtype selectivity and metabolic stability of dinucleoside polyphosphate analogues. Journal of Medicinal Chemistry. 55: 437-48. PMID 22107038 DOI: 10.1021/Jm2013198  0.72
2010 Eliahu S, Lecka J, Reiser G, Haas M, Bigonnesse F, Lévesque SA, Pelletier J, Sévigny J, Fischer B. Diadenosine 5',5''-(boranated)polyphosphonate analogues as selective nucleotide pyrophosphatase/phosphodiesterase inhibitors. Journal of Medicinal Chemistry. 53: 8485-97. PMID 21090681 DOI: 10.1021/Jm100597C  0.72
2010 Stern N, Major DT, Gottlieb HE, Weizman D, Fischer B. What is the conformation of physiologically-active dinucleoside polyphosphates in solution? Conformational analysis of free dinucleoside polyphosphates by NMR and molecular dynamics simulations. Organic & Biomolecular Chemistry. 8: 4637-52. PMID 20714505 DOI: 10.1039/C005122E  0.72
2010 Eliahu S, Martín-Gil A, Perez de Lara MJ, Pintor J, Camden J, Weisman GA, Lecka J, Sévigny J, Fischer B. 2-MeS-beta,gamma-CCl2-ATP is a potent agent for reducing intraocular pressure. Journal of Medicinal Chemistry. 53: 3305-19. PMID 20337495 DOI: 10.1021/Jm100030U  0.72
2010 Eliahu S, Barr HM, Camden J, Weisman GA, Fischer B. A novel insulin secretagogue based on a dinucleoside polyphosphate scaffold. Journal of Medicinal Chemistry. 53: 2472-81. PMID 20175517 DOI: 10.1021/Jm901621H  0.72
2010 Zobel E, Yavin E, Gottlieb HE, Segal M, Fischer B. Oligonucleotides are potent antioxidants acting primarily through metal ion chelation. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 15: 601-20. PMID 20155378 DOI: 10.1007/S00775-010-0628-Z  0.56
2010 Ginsburg-Shmuel T, Haas M, Schumann M, Reiser G, Kalid O, Stern N, Fischer B. 5-OMe-UDP is a potent and selective P2Y(6)-receptor agonist. Journal of Medicinal Chemistry. 53: 1673-85. PMID 20095577 DOI: 10.1021/Jm901450D  0.72
2009 Eliahu SE, Camden J, Lecka J, Weisman GA, Sévigny J, Gélinas S, Fischer B. Identification of hydrolytically stable and selective P2Y(1) receptor agonists. European Journal of Medicinal Chemistry. 44: 1525-36. PMID 18760862 DOI: 10.1016/J.Ejmech.2008.07.015  0.72
2008 Ecke D, Fischer B, Reiser G. Diastereoselectivity of the P2Y11 nucleotide receptor: mutational analysis. British Journal of Pharmacology. 155: 1250-5. PMID 18820714 DOI: 10.1038/Bjp.2008.352  0.72
2007 Laxer A, Gottlieb HE, Fischer B. Molecular recognition of adenosine deaminase: 15N NMR studies. Nucleosides, Nucleotides & Nucleic Acids. 26: 161-80. PMID 17365795 DOI: 10.1080/15257770601112713  0.56
2007 Zylberg J, Ecke D, Fischer B, Reiser G. Structure and ligand-binding site characteristics of the human P2Y11 nucleotide receptor deduced from computational modelling and mutational analysis. The Biochemical Journal. 405: 277-86. PMID 17338680 DOI: 10.1042/Bj20061728  0.72
2006 Ecke D, Tulapurkar ME, Nahum V, Fischer B, Reiser G. Opposite diastereoselective activation of P2Y1 and P2Y11 nucleotide receptors by adenosine 5'-O-(alpha-boranotriphosphate) analogues. British Journal of Pharmacology. 149: 416-23. PMID 16953187 DOI: 10.1038/Sj.Bjp.0706887  0.72
2006 Sharon E, Lévesque SA, Munkonda MN, Sévigny J, Ecke D, Reiser G, Fischer B. Fluorescent N2,N3-epsilon-adenine nucleoside and nucleotide probes: synthesis, spectroscopic properties, and biochemical evaluation. Chembiochem : a European Journal of Chemical Biology. 7: 1361-74. PMID 16871613 DOI: 10.1002/Cbic.200600070  0.72
2006 Nahum V, Tulapurkar M, Lévesque SA, Sévigny J, Reiser G, Fischer B. Diadenosine and diuridine poly(borano)phosphate analogues: synthesis, chemical and enzymatic stability, and activity at P2Y1 and P2Y2 receptors. Journal of Medicinal Chemistry. 49: 1980-90. PMID 16539385 DOI: 10.1021/Jm050955Y  0.72
2004 Sharon E, Zündorf G, Lévesque SA, Beaudoin AR, Reiser G, Fischer B. Fluorescent epsilon-ATP analogues for probing physicochemical properties of proteins. Synthesis, biochemical evaluation, and sensitivity to properties of the medium. Bioorganic & Medicinal Chemistry. 12: 6119-35. PMID 15519157 DOI: 10.1016/J.Bmc.2004.09.011  0.72
2004 Major DT, Nahum V, Wang Y, Reiser G, Fischer B. Molecular recognition in purinergic receptors. 2. Diastereoselectivity of the h-P2Y1-receptor. Journal of Medicinal Chemistry. 47: 4405-16. PMID 15317453 DOI: 10.1021/Jm049771U  0.72
2004 Major DT, Fischer B. Molecular recognition in purinergic receptors. 1. A comprehensive computational study of the h-P2Y1-receptor. Journal of Medicinal Chemistry. 47: 4391-404. PMID 15317452 DOI: 10.1021/Jm049772M  0.96
2004 Tulapurkar ME, Laubinger W, Nahum V, Fischer B, Reiser G. Subtype specific internalization of P2Y1 and P2Y2 receptors induced by novel adenosine 5'-O-(1-boranotriphosphate) derivatives. British Journal of Pharmacology. 142: 869-78. PMID 15197109 DOI: 10.1038/Sj.Bjp.0705859  0.72
2004 Nahum V, Fischer B. Boranophosphate Salts as an Excellent Mimic of Phosphate Salts: Preparation, Characterization, and Properties European Journal of Inorganic Chemistry. 2004: 4124-4131. DOI: 10.1002/Ejic.200400142  0.36
2003 Halbfinger E, Gorochesky K, Lévesque SA, Beaudoin AR, Sheihet L, Margel S, Fischer B. Photoaffinity labeling on magnetic microspheres (PALMm) methodology for topographic mapping: preparation of PALMm reagents and demonstration of biochemical relevance. Organic & Biomolecular Chemistry. 1: 2821-32. PMID 12968331 DOI: 10.1039/B303425A  0.6
2002 Nahum V, Zündorf G, Lévesque SA, Beaudoin AR, Reiser G, Fischer B. Adenosine 5'-O-(1-boranotriphosphate) derivatives as novel P2Y(1) receptor agonists. Journal of Medicinal Chemistry. 45: 5384-96. PMID 12431066 DOI: 10.1021/Jm020251D  0.72
2002 Major DT, Laxer A, Fischer B. Protonation studies of modified adenine and adenine nucleotides by theoretical calculations and (15)N NMR. The Journal of Organic Chemistry. 67: 790-802. PMID 11856021 DOI: 10.1021/Jo0107554  0.96
2002 Gendron FP, Halbfinger E, Fischer B, Beaudoin AR. Inhibitors of NTPDase: Key Players in the Metabolism of Extracellular Purines Advances in Experimental Medicine and Biology. 486: 119-123. PMID 11783467 DOI: 10.1007/0-306-46843-3_24  0.6
2001 Laxer A, Major DT, Gottlieb HE, Fischer B. ((15)N(5))-labeled adenine derivatives: synthesis and studies of tautomerism by (15)N NMR spectroscopy and theoretical calculations. The Journal of Organic Chemistry. 66: 5463-81. PMID 11485471 DOI: 10.1021/Jo010344N  0.96
2001 Zündorf G, Schäfer R, Vöhringer C, Halbfinger E, Fischer B, Reiser G. Novel modified adenosine 5'-triphosphate analogues pharmacologically characterized in human embryonic kidney 293 cells highly expressing rat brain P2Y(1) receptor: Biotinylated analogue potentially suitable for specific P2Y(1) receptor isolation. Biochemical Pharmacology. 61: 1259-69. PMID 11322930 DOI: 10.1016/S0006-2952(01)00593-7  0.72
2000 Gendron F, Halbfinger E, Fischer B, Duval M, D'Orléans-Juste P, Beaudoin AR. Novel inhibitors of nucleoside triphosphate diphosphohydrolases: chemical synthesis and biochemical and pharmacological characterizations. Journal of Medicinal Chemistry. 43: 2239-2247. PMID 10841802 DOI: 10.1021/Jm000020B  0.6
2000 Laxer A, Fischer B. A facile synthesis of (15N2) malononitrile Journal of Labelled Compounds and Radiopharmaceuticals. 43: 47-53. DOI: 10.1002/(Sici)1099-1344(200001)43:1<47::Aid-Jlcr289>3.0.Co;2-K  0.56
1999 Major DT, Halbfinger E, Fischer B. Molecular recognition of modified adenine nucleotides by the P2Y(1)-receptor. 2. A computational approach. Journal of Medicinal Chemistry. 42: 5338-47. PMID 10639277 DOI: 10.1021/Jm9901576  0.96
1999 Halbfinger E, Major DT, Ritzmann M, Ubl J, Reiser G, Boyer JL, Harden KT, Fischer B. Molecular recognition of modified adenine nucleotides by the P2Y(1)-receptor. 1. A synthetic, biochemical, and NMR approach. Journal of Medicinal Chemistry. 42: 5325-37. PMID 10639276 DOI: 10.1021/Jm990156D  0.72
1999 Fischer B, Yefidoff R, Major DT, Rutman-Halili I, Shneyvays V, Zinman T, Jacobson KA, Shainberg A. Characterization of "mini-nucleotides" as P2X receptor agonists in rat cardiomyocyte cultures. An integrated synthetic, biochemical, and theoretical study. Journal of Medicinal Chemistry. 42: 2685-96. PMID 10411489 DOI: 10.1021/Jm990085I  0.96
1996 Boyer JL, Siddiqi S, Fischer B, Romero-Avila T, Jacobson KA, Harden TK. Identification of potent P2Y-purinoceptor agonists that are derivatives of adenosine 5'-monophosphate. British Journal of Pharmacology. 118: 1959-64. PMID 8864529 DOI: 10.1111/j.1476-5381.1996.tb15630.x  0.88
1995 Jacobson KA, Fischer B, van Rhee AM. Molecular probes for muscarinic receptors: functionalized congeners of selective muscarinic antagonists. Life Sciences. 56: 823-30. PMID 10188781 DOI: 10.1016/0024-3205(95)00016-Y  0.88
1995 Van Rhee AM, Fischer B, Van Galen PJ, Jacobson KA. Modelling the P2Y purinoceptor using rhodopsin as template. Drug Design and Discovery. 13: 133-54. PMID 8872457  0.88
1995 Boyer JL, O'Tuel JW, Fischer B, Jacobson KA, Harden TK. Potent agonist action of 2-thioether derivatives of adenine nucleotides at adenylyl cyclase-linked P2Y-purinoceptors. British Journal of Pharmacology. 116: 2611-6. PMID 8590978 DOI: 10.1111/J.1476-5381.1995.Tb17215.X  0.88
1995 Jacobson KA, Fischer B, Ji XD. "Cleavable trifunctional" approach to receptor affinity labeling: chemical regeneration of binding to A1-adenosine receptors. Bioconjugate Chemistry. 6: 255-63. PMID 7632796 DOI: 10.1021/Bc00033A004  0.88
1994 Burnstock G, Fischer B, Hoyle CH, Maillard M, Ziganshin AU, Brizzolara AL, von Isakovics A, Boyer JL, Harden TK, Jacobson KA. Structure Activity Relationships for Derivatives of Adenosine-5'-Triphosphate as Agonists at P(2) Purinoceptors: Heterogeneity Within P(2X) and P(2Y) Subtypes. Drug Development Research. 31: 206-219. PMID 22962511 DOI: 10.1002/Ddr.430310308  0.88
1994 Gallo-Rodriguez C, Ji XD, Melman N, Siegman BD, Sanders LH, Orlina J, Fischer B, Pu Q, Olah ME, Van Galen PJM, Stiles GL, Jacobson KA. STructure-activity relationships of N6-benzyladenosine-5′-uronamides as A3-selective adenosine agonists Journal of Medicinal Chemistry®. 37: 636-646. PMID 8126704 DOI: 10.1021/JM00031A014  0.72
1994 Bo X, Fischer B, Maillard M, Jacobson KA, Burnstock G. Comparative studies on the affinities of ATP derivatives for P2x-purinoceptors in rat urinary bladder. British Journal of Pharmacology. 112: 1151-9. PMID 7952876 DOI: 10.1111/J.1476-5381.1994.Tb13204.X  0.88
1993 Jacobson KA, Gallo-Rodriguez C, Melman N, Fischer B, Maillard M, van Bergen A, van Galen PJ, Karton Y. Structure-activity relationships of 8-styrylxanthines as A2-selective adenosine antagonists. Journal of Medicinal Chemistry. 36: 1333-42. PMID 8496902 DOI: 10.1021/Jm00062A005  0.88
1993 Fischer B, Boyer JL, Hoyle CH, Ziganshin AU, Brizzolara AL, Knight GE, Zimmet J, Burnstock G, Harden TK, Jacobson KA. Identification of potent, selective P2Y-purinoceptor agonists: structure-activity relationships for 2-thioether derivatives of adenosine 5'-triphosphate. Journal of Medicinal Chemistry. 36: 3937-46. PMID 8254622 DOI: 10.1021/Jm00076A023  0.88
1993 Hassner A, Fischer B. New chemistry of oxazoles Heterocycles. 35: 1441-1465. DOI: 10.3987/Rev-92-Sr(T)6  0.72
1991 Hassner A, Fischer B. Novel heterocycles by bis heteroannulation of oxazoles Journal of Organic Chemistry. 56: 3419-3425. DOI: 10.1021/Jo00010A044  0.72
1990 Hassner A, Fischer B. Intramolecular formation of oxazolium salts and their reaction with N- and C-nucleophiles Tetrahedron Letters. 31: 7213-7214. DOI: 10.1016/S0040-4039(00)97282-4  0.72
1989 Hassner A, Fischer B. 4,5- and 2,5-additions to oxazoles Tetrahedron. 45: 6249-6262. DOI: 10.1016/S0040-4020(01)85135-8  0.72
1989 Hassner A, Fischer B. Do oxazoliks undergo Diels-Alder reactions with heterodienophiles? Tetrahedron. 45: 3535-3546. DOI: 10.1016/S0040-4020(01)81032-2  0.72
1986 Herzig J, Nudelman A, Gottlieb HE, Fischer B. Studies in sugar chemistry. 2. A simple method for O-deacylation of polyacylated sugars Journal of Organic Chemistry. 51: 727-730. DOI: 10.1021/Jo00355A026  0.56
1986 Herzig J, Nudelman A, Gottlieb HE, Fischer B. Studies in Sugar Chemistry. Part 2. A Simple Method for O-Deacylation of Polyacylated Sugars. Cheminform. 17. DOI: 10.1002/Chin.198636316  0.56
1985 Fischer B, Nudelman A, Ruse M, Herzig J, Gottlieb HE, Keinan E. A Novel Method For Stereoselective Glucuronidation Cheminform. 16. DOI: 10.1002/Chin.198519322  0.56
1984 Fischer B, Nudelman A, Ruse M, Herzig J, Gottlieb HE, Keinan E. A novel method for stereoselective glucuronidation Journal of Organic Chemistry. 49: 4988-4993. DOI: 10.1021/Jo00199A046  0.56
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