| Year |
Citation |
Score |
| 2017 |
Tesseur I, Nguyen A, Chang B, Li L, Woodling NS, Wyss-Coray T, Luo J. Deficiency in neuronal TGF-β signaling leads to nigrostriatal degeneration and activation of TGF-β signaling protects against MPTP neurotoxicity in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28363982 DOI: 10.1523/Jneurosci.2952-16.2017 |
0.561 |
|
| 2017 |
Espuny-Camacho I, Arranz AM, Fiers M, Snellinx A, Ando K, Munck S, Bonnefont J, Lambot L, Corthout N, Omodho L, Vanden Eynden E, Radaelli E, Tesseur I, Wray S, Ebneth A, et al. Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain. Neuron. PMID 28238547 DOI: 10.1016/J.Neuron.2017.02.001 |
0.625 |
|
| 2017 |
Timmers M, Barão S, Van Broeck B, Tesseur I, Slemmon J, De Waepenaert K, Bogert J, Shaw LM, Engelborghs S, Moechars D, Mercken M, Van Nueten L, Tritsmans L, de Strooper B, Streffer JR. BACE1 Dynamics Upon Inhibition with a BACE Inhibitor and Correlation to Downstream Alzheimer's Disease Markers in Elderly Healthy Participants. Journal of Alzheimer's Disease : Jad. PMID 28157093 DOI: 10.3233/Jad-160829 |
0.533 |
|
| 2017 |
Leinonen V, Rauramaa T, Bottelbergs A, Tesseur I, Ark PVD, Pemberton D, Koivisto AM, Jääskeläinen JE, Hiltunen M, Johansson J, Jokinen P, Rokka J, Haaparanta-Solin M, Solin O, Okamura N, et al. [18F]THK-5117-PET AND [11C]PIB-PET IMAGING IN IDIOPATHIC NORMAL PRESSURE HYDROCEPHALUS (INPH) IN RELATION TO CONFIRMED AMYLOID-β PLAQUES AND TAU IN BRAIN BIOPSIES Alzheimers & Dementia. 13: 1537. DOI: 10.1016/J.Jalz.2017.07.672 |
0.32 |
|
| 2017 |
Tesseur I, Timmers M, Borjesson A, Broeck BV, Slemmon JR, Smekens P, Aguilar M, Baquero M, Frank A, Matias-Guiu J, Boada M, Hugon J, Prins ND, Laske C, Tritsmans L, et al. AMYLOID-β42 (Aβ42) DIFFERENTIALLY CORRELATES WITH CSF TOTAL AND HYPERPHOSPHORYLATED TAU IN AN AMYLOID-POSITIVE VERSUS AMYLOID-NEGATIVE EARLY PRODROMAL AND ASYMPTOMATIC AT-RISK FOR AD POPULATION Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.863 |
0.414 |
|
| 2016 |
Russu A, Broeck BV, Tesseur I, Timmers M, Smekens P, Tritsmans L, Nueten LV, Streffer J. Pharmacokinetic/Pharmacodynamic Modeling Of Csf Ab1-40 Reduction In An Early Alzheimer'S Disease Study Of Jnj-54861911, An Oral Bace1 Inhibitor Alzheimers & Dementia. 12: 612. DOI: 10.1016/J.Jalz.2016.06.1215 |
0.335 |
|
| 2014 |
Serneels L, Tesseur I, De Strooper B. Assay to probe proteolytic processing of Notch by γ-secretase. Methods in Molecular Biology (Clifton, N.J.). 1187: 223-9. PMID 25053493 DOI: 10.1007/978-1-4939-1139-4_17 |
0.482 |
|
| 2014 |
Pimenova AA, Thathiah A, De Strooper B, Tesseur I. Regulation of amyloid precursor protein processing by serotonin signaling. Plos One. 9: e87014. PMID 24466315 DOI: 10.1371/Journal.Pone.0087014 |
0.582 |
|
| 2013 |
Tesseur I, De Strooper B. When the dust settles: what did we learn from the bexarotene discussion? Alzheimer's Research & Therapy. 5: 54. PMID 24229456 DOI: 10.1186/Alzrt218 |
0.576 |
|
| 2013 |
Lo AC, Tesseur I, Scopes DI, Nerou E, Callaerts-Vegh Z, Vermaercke B, Treherne JM, De Strooper B, D'Hooge R. Dose-dependent improvements in learning and memory deficits in APPPS1-21 transgenic mice treated with the orally active Aβ toxicity inhibitor SEN1500. Neuropharmacology. 75: 458-66. PMID 24035915 DOI: 10.1016/J.Neuropharm.2013.08.030 |
0.604 |
|
| 2013 |
Lo AC, Iscru E, Blum D, Tesseur I, Callaerts-Vegh Z, Buée L, De Strooper B, Balschun D, D'Hooge R. Amyloid and tau neuropathology differentially affect prefrontal synaptic plasticity and cognitive performance in mouse models of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 37: 109-25. PMID 23788007 DOI: 10.3233/Jad-122296 |
0.633 |
|
| 2013 |
Tesseur I, Lo AC, Roberfroid A, Dietvorst S, Van Broeck B, Borgers M, Gijsen H, Moechars D, Mercken M, Kemp J, D'Hooge R, De Strooper B. Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models". Science (New York, N.Y.). 340: 924-e. PMID 23704554 DOI: 10.1126/science.1233937 |
0.518 |
|
| 2013 |
Tesseur I, Pimenova AA, Lo AC, Ciesielska M, Lichtenthaler SF, De Maeyer JH, Schuurkes JA, D'Hooge R, De Strooper B. Chronic 5-HT4 receptor activation decreases Aβ production and deposition in hAPP/PS1 mice. Neurobiology of Aging. 34: 1779-89. PMID 23474291 DOI: 10.1016/J.Neurobiolaging.2013.01.020 |
0.545 |
|
| 2013 |
Tesseur I, Lo A, Roberfroid A, Dietvorst S, Van Broeck B, Borgers M, Gijsen H, Moechars D, Mercken M, Kemp J, D’Hooge R, De Strooper B. Bexarotene treatment does not clear β-Amyloid in an AD mouse model and Beagle dogs Molecular Neurodegeneration. 8: P40. DOI: 10.1186/1750-1326-8-S1-P40 |
0.58 |
|
| 2011 |
Moss ML, Powell G, Miller MA, Edwards L, Qi B, Sang QX, De Strooper B, Tesseur I, Lichtenthaler SF, Taverna M, Zhong JL, Dingwall C, Ferdous T, Schlomann U, Zhou P, et al. ADAM9 inhibition increases membrane activity of ADAM10 and controls α-secretase processing of amyloid precursor protein. The Journal of Biological Chemistry. 286: 40443-51. PMID 21956108 DOI: 10.1074/Jbc.M111.280495 |
0.536 |
|
| 2010 |
Jorissen E, Prox J, Bernreuther C, Weber S, Schwanbeck R, Serneels L, Snellinx A, Craessaerts K, Thathiah A, Tesseur I, Bartsch U, Weskamp G, Blobel CP, Glatzel M, De Strooper B, et al. The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 4833-44. PMID 20371803 DOI: 10.1523/Jneurosci.5221-09.2010 |
0.635 |
|
| 2009 |
Tesseur I, Zhang H, Brecht W, Corn J, Gong JS, Yanagisawa K, Michikawa M, Weisgraber K, Huang Y, Wyss-Coray T. Bioactive TGF-beta can associate with lipoproteins and is enriched in those containing apolipoprotein E3. Journal of Neurochemistry. 110: 1254-62. PMID 19549280 DOI: 10.1111/J.1471-4159.2009.06222.X |
0.571 |
|
| 2009 |
Cheng JS, Dubal DB, Kim DH, Legleiter J, Cheng IH, Yu GQ, Tesseur I, Wyss-Coray T, Bonaldo P, Mucke L. Collagen VI protects neurons against Abeta toxicity. Nature Neuroscience. 12: 119-21. PMID 19122666 DOI: 10.1038/Nn.2240 |
0.715 |
|
| 2008 |
Tamgüney G, Giles K, Glidden DV, Lessard P, Wille H, Tremblay P, Groth DF, Yehiely F, Korth C, Moore RC, Tatzelt J, Rubinstein E, Boucheix C, Yang X, Stanley P, ... ... Tesseur I, et al. Genes contributing to prion pathogenesis. The Journal of General Virology. 89: 1777-88. PMID 18559949 DOI: 10.1099/Vir.0.2008/001255-0 |
0.671 |
|
| 2008 |
Cheng JS, Cheng IH, Kim DH, Wu T, Tesseur I, Wyss-Coray T, Bonaldo P, Scearce-Levie K, Mucke L. P1-413: Collagen VI protects neurons against amyloid-beta toxicity Alzheimer's & Dementia. 4: T340-T340. DOI: 10.1016/J.Jalz.2008.05.995 |
0.697 |
|
| 2006 |
Tesseur I, Wyss-Coray T. A role for TGF-beta signaling in neurodegeneration: evidence from genetically engineered models. Current Alzheimer Research. 3: 505-13. PMID 17168649 DOI: 10.2174/156720506779025297 |
0.654 |
|
| 2006 |
Tesseur I, Zou K, Esposito L, Bard F, Berber E, Can JV, Lin AH, Crews L, Tremblay P, Mathews P, Mucke L, Masliah E, Wyss-Coray T. Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology. The Journal of Clinical Investigation. 116: 3060-9. PMID 17080199 DOI: 10.1172/Jci27341 |
0.745 |
|
| 2006 |
Tesseur I, Zou K, Berber E, Zhang H, Wyss-Coray T. Highly sensitive and specific bioassay for measuring bioactive TGF-beta. Bmc Cell Biology. 7: 15. PMID 16549026 DOI: 10.1186/1471-2121-7-15 |
0.542 |
|
| 2005 |
Zhang H, Zou K, Tesseur I, Wyss-Coray T. Small molecule tgf-beta mimetics as potential neuroprotective factors. Current Alzheimer Research. 2: 183-6. PMID 15974916 DOI: 10.2174/1567205053585756 |
0.599 |
|
| 2004 |
Brecht WJ, Harris FM, Chang S, Tesseur I, Yu GQ, Xu Q, Dee Fish J, Wyss-Coray T, Buttini M, Mucke L, Mahley RW, Huang Y. Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2527-34. PMID 15014128 DOI: 10.1523/Jneurosci.4315-03.2004 |
0.755 |
|
| 2004 |
Harris FM, Tesseur I, Brecht WJ, Xu Q, Mullendorff K, Chang S, Wyss-Coray T, Mahley RW, Huang Y. Astroglial regulation of apolipoprotein E expression in neuronal cells. Implications for Alzheimer's disease. The Journal of Biological Chemistry. 279: 3862-8. PMID 14585838 DOI: 10.1074/Jbc.M309475200 |
0.619 |
|
| 2004 |
Brecht WJ, Harris FM, Chang S, Tesseur I, Yu G, Fish JD, Wyss-Coray T, Buttini M, Mucke L, Mahley RW, Huang Y. P2-292 Neuron-specific apoE4 proteolysis is associated with increased tau phosphorylation in the brains of transgenic mice Neurobiology of Aging. 25: S316. DOI: 10.1016/S0197-4580(04)81037-6 |
0.72 |
|
| 2003 |
Brionne TC, Tesseur I, Masliah E, Wyss-Coray T. Loss of TGF-beta 1 leads to increased neuronal cell death and microgliosis in mouse brain. Neuron. 40: 1133-45. PMID 14687548 DOI: 10.1016/S0896-6273(03)00766-9 |
0.637 |
|
| 2003 |
Harris FM, Brecht WJ, Xu Q, Tesseur I, Kekonius L, Wyss-Coray T, Fish JD, Masliah E, Hopkins PC, Scearce-Levie K, Weisgraber KH, Mucke L, Mahley RW, Huang Y. Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 10966-71. PMID 12939405 DOI: 10.1073/Pnas.1434398100 |
0.754 |
|
| 2001 |
Dewachter I, Moechars D, van Dorpe J, Tesseur I, Van den Haute C, Spittaels K, Van Leuven F. Modelling Alzheimer's disease in multiple transgenic mice. Biochemical Society Symposium. 203-10. PMID 11447836 DOI: 10.1042/Bss0670203 |
0.702 |
|
| 2000 |
Tesseur I, Van Dorpe J, Bruynseels K, Bronfman F, Sciot R, Van Lommel A, Van Leuven F. Prominent axonopathy and disruption of axonal transport in transgenic mice expressing human apolipoprotein E4 in neurons of brain and spinal cord. The American Journal of Pathology. 157: 1495-510. PMID 11073810 DOI: 10.1016/S0002-9440(10)64788-8 |
0.749 |
|
| 2000 |
Dewachter I, van Dorpe J, Spittaels K, Tesseur I, Van Den Haute C, Moechars D, Van Leuven F. Modeling Alzheimer's disease in transgenic mice: effect of age and of presenilin1 on amyloid biochemistry and pathology in APP/London mice. Experimental Gerontology. 35: 831-41. PMID 11053674 DOI: 10.1016/S0531-5565(00)00149-2 |
0.689 |
|
| 2000 |
Van Dorpe J, Smeijers L, Dewachter I, Nuyens D, Spittaels K, Van Den Haute C, Mercken M, Moechars D, Laenen I, Kuiperi C, Bruynseels K, Tesseur I, Loos R, Vanderstichele H, Checler F, et al. Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons. The American Journal of Pathology. 157: 1283-98. PMID 11021833 DOI: 10.1016/S0197-4580(00)82614-7 |
0.637 |
|
| 2000 |
Bronfman FC, Tesseur I, Hofker MH, Havekens LM, Van Leuven F. No evidence for cholinergic problems in apolipoprotein E knockout and apolipoprotein E4 transgenic mice. Neuroscience. 97: 411-8. PMID 10828523 DOI: 10.1016/S0306-4522(00)00016-6 |
0.745 |
|
| 2000 |
Tesseur I, Van Dorpe J, Spittaels K, Van den Haute C, Moechars D, Van Leuven F. Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice. The American Journal of Pathology. 156: 951-64. PMID 10702411 DOI: 10.1016/S0002-9440(10)64963-2 |
0.675 |
|
| 1999 |
Umans L, Serneels L, Lorent K, Dewachter I, Tesseur I, Moechars D, Van Leuven F. Lipoprotein receptor-related protein in brain and in cultured neurons of mice deficient in receptor-associated protein and transgenic for apolipoprotein E4 or amyloid precursor protein. Neuroscience. 94: 315-21. PMID 10613521 DOI: 10.1016/S0306-4522(99)00242-0 |
0.584 |
|
| 1999 |
Umans L, Overbergh L, Serneels L, Tesseur I, Van Leuven F. Analysis of expression of genes involved in apolipoprotein E-based lipoprotein metabolism in pregnant mice deficient in the receptor-associated protein, the low density lipoprotein receptor, or apolipoprotein E. Biology of Reproduction. 61: 1216-25. PMID 10529267 DOI: 10.1095/Biolreprod61.5.1216 |
0.563 |
|
| 1999 |
Moechars D, Dewachter I, Lorent K, Reversé D, Baekelandt V, Naidu A, Tesseur I, Spittaels K, Haute CV, Checler F, Godaux E, Cordell B, Van Leuven F. Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain. The Journal of Biological Chemistry. 274: 6483-92. PMID 10037741 DOI: 10.1074/Jbc.274.10.6483 |
0.645 |
|
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