Robertus Antonius de Bruin - Publications

Affiliations: 
MRC LMCB University College London, London, United Kingdom 
Area:
Cell cycle, DNA structure checkpoint
Website:
http://www.ucl.ac.uk/lmcb/research-groups/Bruin.htm

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Herlihy AE, de Bruin RA. The Role of the Transcriptional Response to DNA Replication Stress. Genes. 8. PMID 28257104 DOI: 10.3390/genes8030092  0.359
2016 Bertoli C, Herlihy AE, Pennycook BR, Kriston-Vizi J, de Bruin RA. Sustained E2F-Dependent Transcription Is a Key Mechanism to Prevent Replication-Stress-Induced DNA Damage. Cell Reports. 15: 1412-22. PMID 27160911 DOI: 10.1016/j.celrep.2016.04.036  0.397
2014 Caetano C, Limbo O, Farmer S, Klier S, Dovey C, Russell P, de Bruin RA. Tolerance of deregulated G1/S transcription depends on critical G1/S regulon genes to prevent catastrophic genome instability. Cell Reports. 9: 2279-89. PMID 25533348 DOI: 10.1016/J.Celrep.2014.11.039  0.694
2014 Bertoli C, de Bruin RA. Turning cell cycle entry on its head. Elife. 3: e03475. PMID 24986860  0.306
2014 Klier S, Farmer S, de Bruin RA. Analyzing G1-S transcriptional control. Methods in Molecular Biology (Clifton, N.J.). 1170: 463-76. PMID 24906330 DOI: 10.1007/978-1-4939-0888-2_25  0.667
2013 Bertoli C, Klier S, McGowan C, Wittenberg C, de Bruin RA. Chk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription. Current Biology : Cb. 23: 1629-37. PMID 23954429 DOI: 10.1016/J.Cub.2013.06.063  0.715
2013 Bertoli C, Skotheim JM, de Bruin RA. Control of cell cycle transcription during G1 and S phases. Nature Reviews. Molecular Cell Biology. 14: 518-28. PMID 23877564 DOI: 10.1038/nrm3629  0.68
2013 Harris MR, Lee D, Farmer S, Lowndes NF, de Bruin RA. Binding specificity of the G1/S transcriptional regulators in budding yeast. Plos One. 8: e61059. PMID 23593391 DOI: 10.1371/journal.pone.0061059  0.57
2013 Travesa A, Kalashnikova TI, de Bruin RA, Cass SR, Chahwan C, Lee DE, Lowndes NF, Wittenberg C. Repression of G1/S transcription is mediated via interaction of the GTB motifs of Nrm1 and Whi5 with Swi6. Molecular and Cellular Biology. 33: 1476-86. PMID 23382076 DOI: 10.1128/Mcb.01333-12  0.729
2012 Smolka MB, Bastos de Oliveira FM, Harris MR, de Bruin RA. The checkpoint transcriptional response: make sure to turn it off once you are satisfied. Cell Cycle (Georgetown, Tex.). 11: 3166-74. PMID 22895177 DOI: 10.4161/Cc.21197  0.585
2012 Travesa A, Kuo D, de Bruin RA, Kalashnikova TI, Guaderrama M, Thai K, Aslanian A, Smolka MB, Yates JR, Ideker T, Wittenberg C. DNA replication stress differentially regulates G1/S genes via Rad53-dependent inactivation of Nrm1. The Embo Journal. 31: 1811-22. PMID 22333915 DOI: 10.1038/Emboj.2012.28  0.741
2012 Bastos de Oliveira FM, Harris MR, Brazauskas P, de Bruin RA, Smolka MB. Linking DNA replication checkpoint to MBF cell-cycle transcription reveals a distinct class of G1/S genes. The Embo Journal. 31: 1798-810. PMID 22333912 DOI: 10.1038/Emboj.2012.27  0.572
2011 Caetano C, Klier S, de Bruin RA. Phosphorylation of the MBF repressor Yox1p by the DNA replication checkpoint keeps the G1/S cell-cycle transcriptional program active. Plos One. 6: e17211. PMID 21359180 DOI: 10.1371/journal.pone.0017211  0.708
2009 Aligianni S, Lackner DH, Klier S, Rustici G, Wilhelm BT, Marguerat S, Codlin S, Brazma A, de Bruin RA, Bähler J. The fission yeast homeodomain protein Yox1p binds to MBF and confines MBF-dependent cell-cycle transcription to G1-S via negative feedback. Plos Genetics. 5: e1000626. PMID 19714215 DOI: 10.1371/Journal.Pgen.1000626  0.747
2009 Wagner MV, Smolka MB, de Bruin RA, Zhou H, Wittenberg C, Dowdy SF. Whi5 regulation by site specific CDK-phosphorylation in Saccharomyces cerevisiae. Plos One. 4: e4300. PMID 19172996 DOI: 10.1371/Journal.Pone.0004300  0.663
2009 de Bruin RA, Wittenberg C. All eukaryotes: before turning off G1-S transcription, please check your DNA. Cell Cycle (Georgetown, Tex.). 8: 214-7. PMID 19158488 DOI: 10.4161/Cc.8.2.7412  0.739
2008 de Bruin RA, Kalashnikova TI, Wittenberg C. Stb1 collaborates with other regulators to modulate the G1-specific transcriptional circuit. Molecular and Cellular Biology. 28: 6919-28. PMID 18794370 DOI: 10.1128/Mcb.00211-08  0.747
2008 Souer E, Rebocho AB, Bliek M, Kusters E, de Bruin RA, Koes R. Patterning of inflorescences and flowers by the F-Box protein DOUBLE TOP and the LEAFY homolog ABERRANT LEAF AND FLOWER of petunia. The Plant Cell. 20: 2033-48. PMID 18713949 DOI: 10.1105/tpc.108.060871  0.339
2008 de Bruin RA, Kalashnikova TI, Aslanian A, Wohlschlegel J, Chahwan C, Yates JR, Russell P, Wittenberg C. DNA replication checkpoint promotes G1-S transcription by inactivating the MBF repressor Nrm1. Proceedings of the National Academy of Sciences of the United States of America. 105: 11230-5. PMID 18682565 DOI: 10.1073/Pnas.0801106105  0.757
2008 Ashe M, de Bruin RA, Kalashnikova T, McDonald WH, Yates JR, Wittenberg C. The SBF- and MBF-associated protein Msa1 is required for proper timing of G1-specific transcription in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 283: 6040-9. PMID 18160399 DOI: 10.1074/Jbc.M708248200  0.749
2007 Limbo O, Chahwan C, Yamada Y, de Bruin RA, Wittenberg C, Russell P. Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination. Molecular Cell. 28: 134-46. PMID 17936710 DOI: 10.1016/J.Molcel.2007.09.009  0.674
2006 de Bruin RA, Kalashnikova TI, Chahwan C, McDonald WH, Wohlschlegel J, Yates J, Russell P, Wittenberg C. Constraining G1-specific transcription to late G1 phase: the MBF-associated corepressor Nrm1 acts via negative feedback. Molecular Cell. 23: 483-96. PMID 16916637 DOI: 10.1016/J.Molcel.2006.06.025  0.722
2004 de Bruin RA, McDonald WH, Kalashnikova TI, Yates J, Wittenberg C. Cln3 activates G1-specific transcription via phosphorylation of the SBF bound repressor Whi5. Cell. 117: 887-98. PMID 15210110 DOI: 10.1016/J.Cell.2004.05.025  0.749
1997 Stam M, De Bruin R, Kenter S, Van der Hoorn RAL, Van Blokland R, Mol JNM, Kooter JM. Post-transcriptional silencing of chalcone synthase in petunia by inverted transgene repeats Plant Journal. 12: 63-82.  0.374
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