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Sagar B. Kudchodkar, Ph.D. - Publications

Affiliations: 
2007 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Virology Biology, Cell Biology
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Tebas P, Roberts CC, Muthumani K, Reuschel EL, Kudchodkar SB, Zaidi FI, White S, Khan AS, Racine T, Choi H, Boyer J, Park YK, Trottier S, Remigio C, Krieger D, et al. Safety and Immunogenicity of an Anti-Zika Virus DNA Vaccine. The New England Journal of Medicine. 385: e35. PMID 34525286 DOI: 10.1056/NEJMoa1708120  0.314
2020 Choi H, Kudchodkar SB, Ho M, Reuschel EL, Reynolds E, Xu Z, Bordoloi D, Ugen KE, Tebas P, Kim J, Abdel-Mohsen M, Thangamani S, Weiner DB, Muthumani K. A novel synthetic DNA vaccine elicits protective immune responses against Powassan virus. Plos Neglected Tropical Diseases. 14: e0008788. PMID 33119599 DOI: 10.1371/journal.pntd.0008788  0.353
2020 Zankharia US, Kudchodkar S, Khoshnejad M, Perales-Puchalt A, Choi H, Ho M, Zaidi F, Ugen KE, Kim JJ, Weiner DB, Muthumani K. Neutralization of hepatitis B virus by a novel DNA-encoded monoclonal antibody. Human Vaccines & Immunotherapeutics. 1-9. PMID 32463327 DOI: 10.1080/21645515.2020.1763686  0.351
2019 Choi H, Kudchodkar SB, Reuschel EL, Asija K, Borole P, Agarwal S, Van Gorder L, Reed CC, Gulendran G, Ramos S, Broderick KE, Kim JJ, Ugen KE, Kobinger G, Siegel DL, et al. Synthetic nucleic acid antibody prophylaxis confers rapid and durable protective immunity against Zika virus challenge. Human Vaccines & Immunotherapeutics. 1-12. PMID 31799896 DOI: 10.1080/21645515.2019.1688038  0.417
2019 Modjarrad K, Roberts CC, Mills KT, Castellano AR, Paolino K, Muthumani K, Reuschel EL, Robb ML, Racine T, Oh MD, Lamarre C, Zaidi FI, Boyer J, Kudchodkar SB, Jeong M, et al. Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial. The Lancet. Infectious Diseases. PMID 31351922 DOI: 10.1016/S1473-3099(19)30266-X  0.354
2019 Esquivel RN, Patel A, Kudchodkar SB, Park DH, Stettler K, Beltramello M, Allen JW, Mendoza J, Ramos S, Choi H, Borole P, Asija K, Bah M, Shaheen S, Chen J, et al. In Vivo Delivery of a DNA-Encoded Monoclonal Antibody Protects Non-human Primates against Zika Virus. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30962164 DOI: 10.1016/J.Ymthe.2019.03.005  0.403
2019 Choi H, Kudchodkar SB, Reuschel EL, Asija K, Borole P, Ho M, Wojtak K, Reed C, Ramos S, Bopp NE, Aguilar PV, Weaver SC, Kim JJ, Humeau L, Tebas P, et al. Protective immunity by an engineered DNA vaccine for Mayaro virus. Plos Neglected Tropical Diseases. 13: e0007042. PMID 30730897 DOI: 10.1371/Journal.Pntd.0007042  0.449
2018 Tang L, Zheng Y, Melo MB, Mabardi L, Castaño AP, Xie YQ, Li N, Kudchodkar SB, Wong HC, Jeng EK, Maus MV, Irvine DJ. Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery. Nature Biotechnology. PMID 29985479 DOI: 10.1038/Nbt.4181  0.345
2018 Kudchodkar SB, Choi H, Reuschel EL, Esquivel R, Jin-Ah Kwon J, Jeong M, Maslow JN, Reed CC, White S, Kim JJ, Kobinger GP, Tebas P, Weiner DB, Muthumani K. Rapid response to an emerging infectious disease - Lessons learned from development of a synthetic DNA vaccine targeting Zika virus. Microbes and Infection. PMID 29555345 DOI: 10.1016/J.Micinf.2018.03.001  0.431
2017 Tebas P, Roberts CC, Muthumani K, Reuschel EL, Kudchodkar SB, Zaidi FI, White S, Khan AS, Racine T, Choi H, Boyer J, Park YK, Trottier S, Remigio C, Krieger D, et al. Safety and Immunogenicity of an Anti-Zika Virus DNA Vaccine - Preliminary Report. The New England Journal of Medicine. PMID 28976850 DOI: 10.1056/Nejmoa1708120  0.4
2017 Muthumani K, Marnin L, Kudchodkar SB, Perales-Puchalt A, Choi H, Agarwal S, Scott VL, Reuschel EL, Zaidi FI, Duperret EK, Wise MC, Kraynyak KA, Ugen KE, Sardesai NY, Joseph Kim J, et al. Novel prostate cancer immunotherapy with a DNA-encoded anti-prostate-specific membrane antigen monoclonal antibody. Cancer Immunology, Immunotherapy : Cii. PMID 28819703 DOI: 10.1007/S00262-017-2042-7  0.304
2017 Castano A, Tang L, Kudchodkar S, Darrell I, Maus M. Abstract B59: Enhancing T-cell therapy through TCR signaling-responsive nanogel drug delivery Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-B59  0.348
2017 Tebas P, Roberts CC, Muthumani K, Reuschel E, White S, Khan AS, Racine T, Choi H, Zaidi F, Boyer J, Kudchodkar S, Park YK, Trottier S, Remigio C, Krieger D, et al. ZIKA-001: Safety and Immunogenicity of an Engineered DNA Vaccine Against ZIKA virus infection Open Forum Infectious Diseases. 4: S300-S301. DOI: 10.1093/Ofid/Ofx163.693  0.402
2016 Muthumani K, Griffin BD, Agarwal S, Kudchodkar SB, Reuschel EL, Choi H, Kraynyak KA, Duperret EK, Keaton AA, Chung C, Kim YK, Booth SA, Racine T, Yan J, Morrow MP, et al. In vivo protection against ZIKV infection and pathogenesis through passive antibody transfer and active immunisation with a prMEnv DNA vaccine. Npj Vaccines. 1: 16021. PMID 29263859 DOI: 10.1038/npjvaccines.2016.21  0.391
2016 Fraietta JA, Beckwith KA, Patel PR, Ruella M, Zheng Z, Barrett DM, Lacey SF, Melenhorst JJ, McGettigan SE, Cook DR, Zhang C, Xu J, Do P, Hulitt J, Kudchodkar SB, et al. Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia. Blood. PMID 26813675 DOI: 10.1182/Blood-2015-11-679134  0.329
2016 Reuschel EL, Muthumani K, Kraynyak K, Tingey C, Kudchodkar SB, Khan AS, Sardesai NY, Kim JJ, Maslow J, Park YK, Kobinger G, Falzarano D, Feldman H, Weiner DB. 436. Developing a Synthetic DNA Vaccine for an Emerging Pathogen - Middle East Respiratory Syndrome Molecular Therapy. 24: S172-S173. DOI: 10.1016/S1525-0016(16)33245-2  0.441
2016 Muthumani K, Chung C, Agarwal S, Plyler R, Kudchodkar S, Flingai S, Ugen K, Kim J, Sardesai N, Weiner DB. 401. In Vivo Expression of Plasmid Encoded IgG for PD-1 or LAG3 by Synthetic DNA as a New Tool for Cancer Immunotherapy Molecular Therapy. 24: S159. DOI: 10.1016/S1525-0016(16)33210-5  0.379
2015 Kudchodkar SB, Tang L, Jeng EK, Wong HC, Irvine DJ, Maus MV. 517. Improving CAR T Cell Efficacy for Solid Tumors By Nanogel-Based Delivery of Immunomodulatory Proteins Molecular Therapy. 23: S207. DOI: 10.1016/S1525-0016(16)34126-0  0.342
2014 Shedlock DJ, Tingey C, Mahadevan L, Hutnick N, Reuschel EL, Kudchodkar S, Flingai S, Yan J, Kim JJ, Ugen KE, Weiner DB, Muthumani K. Co-Administration of Molecular Adjuvants Expressing NF-Kappa B Subunit p65/RelA or Type-1 Transactivator T-bet Enhance Antigen Specific DNA Vaccine-Induced Immunity. Vaccines. 2: 196-215. PMID 26344618 DOI: 10.3390/Vaccines2020196  0.425
2013 Flingai S, Czerwonko M, Goodman J, Kudchodkar SB, Muthumani K, Weiner DB. Synthetic DNA vaccines: improved vaccine potency by electroporation and co-delivered genetic adjuvants. Frontiers in Immunology. 4: 354. PMID 24204366 DOI: 10.3389/Fimmu.2013.00354  0.367
2009 Kudchodkar SB, Levine B. Viruses and autophagy. Reviews in Medical Virology. 19: 359-78. PMID 19750559 DOI: 10.1002/Rmv.630  0.342
2007 Kudchodkar SB, Del Prete GQ, Maguire TG, Alwine JC. AMPK-mediated inhibition of mTOR kinase is circumvented during immediate-early times of human cytomegalovirus infection. Journal of Virology. 81: 3649-51. PMID 17215282 DOI: 10.1128/Jvi.02079-06  0.612
2006 Kudchodkar SB, Yu Y, Maguire TG, Alwine JC. Human cytomegalovirus infection alters the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing complexes. Proceedings of the National Academy of Sciences of the United States of America. 103: 14182-7. PMID 16959881 DOI: 10.1073/Pnas.0605825103  0.621
2005 Kutzler MA, Robinson TM, Chattergoon MA, Choo DK, Choo AY, Choe PY, Ramanathan MP, Parkinson R, Kudchodkar S, Tamura Y, Sidhu M, Roopchand V, Kim JJ, Pavlakis GN, Felber BK, et al. Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help. Journal of Immunology (Baltimore, Md. : 1950). 175: 112-23. PMID 15972637 DOI: 10.4049/Jimmunol.175.1.112  0.363
2005 Yu Y, Kudchodkar SB, Alwine JC. Effects of simian virus 40 large and small tumor antigens on mammalian target of rapamycin signaling: small tumor antigen mediates hypophosphorylation of eIF4E-binding protein 1 late in infection. Journal of Virology. 79: 6882-9. PMID 15890927 DOI: 10.1128/Jvi.79.11.6882-6889.2005  0.634
2004 Kudchodkar SB, Yu Y, Maguire TG, Alwine JC. Human cytomegalovirus infection induces rapamycin-insensitive phosphorylation of downstream effectors of mTOR kinase. Journal of Virology. 78: 11030-9. PMID 15452223 DOI: 10.1128/Jvi.78.20.11030-11039.2004  0.609
2003 Lin CL, Li H, Wang Y, Zhu FX, Kudchodkar S, Yuan Y. Kaposi's sarcoma-associated herpesvirus lytic origin (ori-Lyt)-dependent DNA replication: identification of the ori-Lyt and association of K8 bZip protein with the origin. Journal of Virology. 77: 5578-88. PMID 12719550 DOI: 10.1128/Jvi.77.10.5578-5588.2003  0.31
2002 Boyer JD, Chattergoon M, Muthumani K, Kudchodkar S, Kim J, Bagarazzi M, Pavlakis G, Sekaly R, Weiner DB. Next generation DNA vaccines for HIV-1. Journal of Liposome Research. 12: 137-42. PMID 12604047 DOI: 10.1081/Lpr-120004786  0.385
2002 Muthumani K, Zhang D, Hwang DS, Kudchodkar S, Dayes NS, Desai BM, Malik AS, Yang JS, Chattergoon MA, Maguire HC, Weiner DB. Adenovirus encoding HIV-1 Vpr activates caspase 9 and induces apoptotic cell death in both p53 positive and negative human tumor cell lines. Oncogene. 21: 4613-25. PMID 12096338 DOI: 10.1038/Sj.Onc.1205549  0.332
2002 Muthumani K, Kudchodkar S, Zhang D, Bagarazzi ML, Kim JJ, Boyer JD, Ayyavoo V, Pavlakis GN, Weiner DB. Issues for improving multiplasmid DNA vaccines for HIV-1. Vaccine. 20: 1999-2003. PMID 11983262 DOI: 10.1016/S0264-410X(02)00086-5  0.383
2002 Ayyavoo V, Muthumani K, Kudchodkar S, Zhang D, Ramanathan P, Dayes NS, Kim JJ, Sin JI, Montaner LJ, Weiner DB. HIV-1 viral protein R compromises cellular immune function in vivo. International Immunology. 14: 13-22. PMID 11751747 DOI: 10.1093/Intimm/14.1.13  0.425
2001 Dickey CA, Morgan DG, Kudchodkar S, Weiner DB, Bai Y, Cao C, Gordon MN, Ugen KE. Duration and specificity of humoral immune responses in mice vaccinated with the Alzheimer's disease-associated beta-amyloid 1-42 peptide. Dna and Cell Biology. 20: 723-9. PMID 11788050 DOI: 10.1089/10445490152717587  0.313
2001 Yang JS, Kim JJ, Hwang D, Choo AY, Dang K, Maguire H, Kudchodkar S, Ramanathan MP, Weiner DB. Induction of potent Th1-type immune responses from a novel DNA vaccine for West Nile virus New York isolate (WNV-NY1999). The Journal of Infectious Diseases. 184: 809-16. PMID 11550123 DOI: 10.1086/323395  0.424
2001 Fernando KP, Muthumani K, Zhang D, Kudchodkar S, Weiner DB. HIV DNA Vaccination: Advances and Experiences Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz. 44: 1076-1082. DOI: 10.1007/S00103-001-0291-1  0.368
2000 Ayyavoo V, Kudchodkar S, Ramanathan MP, Le P, Muthumani K, Megalai NM, Dentchev T, Santiago-Barrios L, Mrinalini C, Weiner DB. Immunogenicity of a novel DNA vaccine cassette expressing multiple human immunodeficiency virus (HIV-1) accessory genes. Aids (London, England). 14: 1-9. PMID 10714562 DOI: 10.1097/00002030-200001070-00001  0.37
2000 Muthumani K, Kudchodkar S, Papasavvas E, Montaner LJ, Weiner DB, Ayyavoo V. HIV-1 Vpr regulates expression of β chemokines in human primary lymphocytes and macrophages Journal of Leukocyte Biology. 68: 366-372. DOI: 10.1189/Jlb.68.3.366  0.369
1997 Agadjanyan MG, Trivedi NN, Kudchodkar S, Bennett M, Levine W, Lin A, Boyer J, Levy D, Ugen KE, Kim JJ, Weiner DB. An HIV type 2 DNA vaccine induces cross-reactive immune responses against HIV type 2 and SIV. Aids Research and Human Retroviruses. 13: 1561-72. PMID 9430248 DOI: 10.1089/Aid.1997.13.1561  0.372
1997 Ayyavoo V, Mahboubi A, Mahalingam S, Ramalingam R, Kudchodkar S, Williams WV, Green DR, Weiner DB. HIV-1 Vpr suppresses immune activation and apoptosis through regulation of nuclear factor kappa B. Nature Medicine. 3: 1117-23. PMID 9334723 DOI: 10.1038/Nm1097-1117  0.339
1997 Ayyavoo V, Mahalingam S, Rafaeli Y, Kudchodkar S, Chang D, Nagashunmugam T, Williams WV, Weiner DB. HIV-1 viral protein R (Vpr) regulates viral replication and cellular proliferation in T cells and monocytoid cells in vitro. Journal of Leukocyte Biology. 62: 93-9. PMID 9225999 DOI: 10.1002/Jlb.62.1.93  0.392
1994 Ugen KE, Wang B, Ayyavoo V, Agadjanyan M, Boyer J, Li F, Kudchodkar S, Lin J, Merva M, Fernandes L, Williams WV, Weiner DB. DNA inoculation as a novel vaccination method against human retroviruses with rheumatic disease associations Immunologic Research. 13: 154-162. PMID 7775806 DOI: 10.1007/Bf02918276  0.467
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