Yunjeong Kim, Ph.D. - Publications

Affiliations: 
2001 Ohio State University, Columbus, Columbus, OH 
Area:
Veterinary Science Biology, Molecular Biology, Immunology

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kim Y, Pool E, Kim E, Dampalla CS, Nguyen HN, Johnson DK, Lovell S, Groutas WC, Chang K-O. Potent small molecule inhibitors against the 3C protease of foot-and-mouth disease virus. Microbiology Spectrum. e0337223. PMID 38466127 DOI: 10.1128/spectrum.03372-23  0.342
2022 Perera KD, Johnson D, Lovell S, Groutas WC, Chang KO, Kim Y. Potent Protease Inhibitors of Highly Pathogenic Lagoviruses: Rabbit Hemorrhagic Disease Virus and European Brown Hare Syndrome Virus. Microbiology Spectrum. e0014222. PMID 35766511 DOI: 10.1128/spectrum.00142-22  0.332
2021 Dampalla CS, Rathnayake AD, Perera KD, Jesri AM, Nguyen HN, Miller MJ, Thurman HA, Zheng J, Kashipathy MM, Battaile KP, Lovell S, Perlman S, Kim Y, Groutas WC, Chang KO. Structure-Guided Design of Potent Inhibitors of SARS-CoV-2 3CL Protease: Structural, Biochemical, and Cell-Based Studies. Journal of Medicinal Chemistry. PMID 34865476 DOI: 10.1021/acs.jmedchem.1c01037  0.31
2020 Rathnayake AD, Kim Y, Dampalla CS, Nguyen HN, Jesri AM, Kashipathy MM, Lushington GH, Battaile KP, Lovell S, Chang KO, Groutas WC. Structure-Guided Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease. Journal of Medicinal Chemistry. PMID 32945669 DOI: 10.1021/Acs.Jmedchem.0C01252  0.401
2020 Rathnayake AD, Zheng J, Kim Y, Perera KD, Mackin S, Meyerholz DK, Kashipathy MM, Battaile KP, Lovell S, Perlman S, Groutas WC, Chang KO. 3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. Science Translational Medicine. PMID 32747425 DOI: 10.1126/Scitranslmed.Abc5332  0.386
2020 Oh C, Kim Y, Chang KO. Caspase-mediated cleavage of nucleocapsid protein of a protease-independent porcine epidemic diarrhea virus strain. Virus Research. 285: 198026. PMID 32482590 DOI: 10.1016/J.Virusres.2020.198026  0.335
2019 Perera KD, Rathnayake AD, Liu H, Pedersen NC, Groutas WC, Chang KO, Kim Y. Characterization of amino acid substitutions in feline coronavirus 3C-like protease from a cat with feline infectious peritonitis treated with a protease inhibitor. Veterinary Microbiology. 237: 108398. PMID 31585653 DOI: 10.1016/J.Vetmic.2019.108398  0.336
2019 Oh C, Kim Y, Chang KO. Proteases facilitate the endosomal escape of porcine epidemic diarrhea virus during entry into host cells. Virus Research. 197730. PMID 31445102 DOI: 10.1016/J.Virusres.2019.197730  0.363
2019 Galasiti Kankanamalage AC, Weerawarna PM, Rathnayake AD, Kim Y, Mehzabeen N, Battaile KP, Lovell S, Chang KO, Groutas WC. Putative Structural Rearrangements Associated with the Interaction of Macrocyclic Inhibitors with Norovirus 3CL Protease. Proteins. PMID 30883881 DOI: 10.1002/Prot.25682  0.417
2019 Chang KO, Kim Y, Lovell S, Rathnayake AD, Groutas WC. Antiviral Drug Discovery: Norovirus Proteases and Development of Inhibitors. Viruses. 11. PMID 30823509 DOI: 10.3390/V11020197  0.403
2018 Perera KD, Galasiti Kankanamalage AC, Rathnayake AD, Honeyfield A, Groutas W, Chang KO, Kim Y. Protease inhibitors broadly effective against feline, ferret and mink coronaviruses. Antiviral Research. PMID 30342822 DOI: 10.1016/J.Antiviral.2018.10.015  0.404
2018 Galasiti Kankanamalage AC, Kim Y, Damalanka VC, Rathnayake AD, Fehr AR, Mehzabeen N, Battaile KP, Lovell S, Lushington GH, Perlman S, Chang KO, Groutas WC. Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element. European Journal of Medicinal Chemistry. 150: 334-346. PMID 29544147 DOI: 10.1016/J.Ejmech.2018.03.004  0.367
2018 Kim Y, Chang KO. Fexaramine as an entry blocker for feline caliciviruses. Antiviral Research. PMID 29454892 DOI: 10.1016/J.Antiviral.2018.02.009  0.384
2018 Kim Y, Chang KO. Protein Disulfide Isomerases as potential therapeutic targets for Influenza A and B Viruses. Virus Research. PMID 29382552 DOI: 10.1016/J.Virusres.2018.01.010  0.361
2018 Damalanka VC, Kim Y, Galasiti Kankanamalage AC, Rathnayake AD, Mehzabeen N, Battaile KP, Lovell S, Nguyen HN, Lushington GH, Chang KO, Groutas WC. Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease. European Journal of Medicinal Chemistry. 143: 881-890. PMID 29227928 DOI: 10.1016/J.Ejmech.2017.12.014  0.363
2017 Kim Y, Oh C, Shivanna V, Hesse RA, Chang KO. Trypsin-independent porcine epidemic diarrhea virus US strain with altered virus entry mechanism. Bmc Veterinary Research. 13: 356. PMID 29178878 DOI: 10.1186/S12917-017-1283-1  0.4
2017 Galasiti Kankanamalage AC, Kim Y, Rathnayake AD, Alliston KR, Butler MM, Cardinale SC, Bowlin TL, Groutas WC, Chang KO. Design, Synthesis, and Evaluation of Novel Prodrugs of Transition State Inhibitors of Norovirus 3CL Protease. Journal of Medicinal Chemistry. PMID 28671827 DOI: 10.1021/Acs.Jmedchem.7B00497  0.331
2016 Damalanka VC, Kim Y, Galasiti Kankanamalage AC, Lushington GH, Mehzabeen N, Battaile KP, Lovell S, Chang KO, Groutas WC. Design, synthesis, and evaluation of a novel series of macrocyclic inhibitors of norovirus 3CL protease. European Journal of Medicinal Chemistry. 127: 41-61. PMID 28038326 DOI: 10.1016/J.Ejmech.2016.12.033  0.397
2016 Galasiti Kankanamalage AC, Kim Y, Rathnayake AD, Damalanka VC, Weerawarna PM, Doyle ST, Alsoudi AF, Dissanayake DM, Lushington GH, Mehzabeen N, Battaile KP, Lovell S, Chang KO, Groutas WC. Structure-based exploration and exploitation of the S4 subsite of norovirus 3CL protease in the design of potent and permeable inhibitors. European Journal of Medicinal Chemistry. 126: 502-516. PMID 27914364 DOI: 10.1016/J.Ejmech.2016.11.027  0.382
2016 Weerawarna PM, Kim Y, Galasiti Kankanamalage AC, Damalanka VC, Lushington GH, Alliston KR, Mehzabeen N, Battaile KP, Lovell S, Chang KO, Groutas WC. Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: Structural, biochemical, spectroscopic, and antiviral studies. European Journal of Medicinal Chemistry. 119: 300-318. PMID 27235842 DOI: 10.1016/J.Ejmech.2016.04.013  0.391
2016 Kim Y, Liu H, Galasiti Kankanamalage AC, Weerasekara S, Hua DH, Groutas WC, Chang KO, Pedersen NC. Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor. Plos Pathogens. 12: e1005531. PMID 27027316 DOI: 10.1371/Journal.Ppat.1005531  0.399
2016 Galasiti Kankanamalage AC, Weerawarna PM, Kim Y, Chang KO, Groutas WC. Anti-Norovirus Therapeutics: A Patent Review (2010-2015). Expert Opinion On Therapeutic Patents. PMID 26881878 DOI: 10.1517/13543776.2016.1153065  0.35
2016 Damalanka VC, Kim Y, Alliston KR, Weerawarna PM, Galasiti Kankanamalage AC, Lushington GH, Mehzabeen N, Battaile KP, Lovell SW, Chang KO, Groutas WC. Oxadiazole-Based Cell Permeable Macrocyclic Transition State Inhibitors of Norovirus 3CL Protease. Journal of Medicinal Chemistry. PMID 26823007 DOI: 10.1021/Acs.Jmedchem.5B01464  0.418
2015 Kim Y, Galasiti Kankanamalage AC, Damalanka VC, Weerawarna PM, Groutas WC, Chang KO. Potent Inhibition of Enterovirus D68 and Human Rhinoviruses by Dipeptidyl Aldehydes and α-Ketoamides. Antiviral Research. PMID 26658373 DOI: 10.1016/J.Antiviral.2015.11.010  0.321
2015 Kim Y, Galasiti Kankanamalage AC, Chang KO, Groutas WC. Recent Advances in the Discovery of Norovirus Therapeutics. Journal of Medicinal Chemistry. PMID 26258852 DOI: 10.1021/Acs.Jmedchem.5B00762  0.304
2015 Shivanna V, Kim Y, Chang KO. Ceramide formation mediated by acid sphingomyelinase facilitates endosomal escape of caliciviruses. Virology. 483: 218-28. PMID 25985440 DOI: 10.1016/J.Virol.2015.04.022  0.332
2015 Galasiti Kankanamalage AC, Kim Y, Weerawarna PM, Uy RA, Damalanka VC, Mandadapu SR, Alliston KR, Mehzabeen N, Battaile KP, Lovell S, Chang KO, Groutas WC. Structure-guided design and optimization of dipeptidyl inhibitors of norovirus 3CL protease. Structure-activity relationships and biochemical, X-ray crystallographic, cell-based, and in vivo studies. Journal of Medicinal Chemistry. 58: 3144-55. PMID 25761614 DOI: 10.1021/Jm5019934  0.406
2015 Kim Y, Shivanna V, Narayanan S, Prior AM, Weerasekara S, Hua DH, Kankanamalage AC, Groutas WC, Chang KO. Broad-spectrum inhibitors against 3C-like proteases of feline coronaviruses and feline caliciviruses. Journal of Virology. 89: 4942-50. PMID 25694593 DOI: 10.1128/Jvi.03688-14  0.42
2014 Shivanna V, Kim Y, Chang KO. Endosomal acidification and cathepsin L activity is required for calicivirus replication. Virology. 464: 287-95. PMID 25108379 DOI: 10.1016/J.Virol.2014.07.025  0.317
2014 Shivanna V, Kim Y, Chang KO. The crucial role of bile acids in the entry of porcine enteric calicivirus. Virology. 456: 268-78. PMID 24889246 DOI: 10.1016/J.Virol.2014.04.002  0.301
2013 Prior AM, Kim Y, Weerasekara S, Moroze M, Alliston KR, Uy RA, Groutas WC, Chang KO, Hua DH. Design, synthesis, and bioevaluation of viral 3C and 3C-like protease inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 6317-20. PMID 24125888 DOI: 10.1016/J.Bmcl.2013.09.070  0.367
2013 Takahashi D, Kim Y, Lovell S, Prakash O, Groutas WC, Chang KO. Structural and inhibitor studies of norovirus 3C-like proteases. Virus Research. 178: 437-44. PMID 24055466 DOI: 10.1016/J.Virusres.2013.09.008  0.365
2013 Mandadapu SR, Gunnam MR, Galasiti Kankanamalage AC, Uy RA, Alliston KR, Lushington GH, Kim Y, Chang KO, Groutas WC. Potent inhibition of norovirus by dipeptidyl α-hydroxyphosphonate transition state mimics. Bioorganic & Medicinal Chemistry Letters. 23: 5941-4. PMID 24054123 DOI: 10.1016/J.Bmcl.2013.08.073  0.307
2013 Mandadapu SR, Weerawarna PM, Prior AM, Uy RA, Aravapalli S, Alliston KR, Lushington GH, Kim Y, Hua DH, Chang KO, Groutas WC. Macrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus. Bioorganic & Medicinal Chemistry Letters. 23: 3709-12. PMID 23727045 DOI: 10.1016/J.Bmcl.2013.05.021  0.327
2013 Kim Y, Mandadapu SR, Groutas WC, Chang KO. Potent inhibition of feline coronaviruses with peptidyl compounds targeting coronavirus 3C-like protease. Antiviral Research. 97: 161-8. PMID 23219425 DOI: 10.1016/J.Antiviral.2012.11.005  0.421
2013 Mandadapu SR, Gunnam MR, Tiew KC, Uy RA, Prior AM, Alliston KR, Hua DH, Kim Y, Chang KO, Groutas WC. Inhibition of norovirus 3CL protease by bisulfite adducts of transition state inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 62-5. PMID 23218713 DOI: 10.1016/J.Bmcl.2012.11.026  0.368
2012 Kim Y, Lovell S, Tiew KC, Mandadapu SR, Alliston KR, Battaile KP, Groutas WC, Chang KO. Broad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, noroviruses, and coronaviruses. Journal of Virology. 86: 11754-62. PMID 22915796 DOI: 10.1128/Jvi.01348-12  0.4
2012 Jung K, Wang Q, Kim Y, Scheuer K, Zhang Z, Shen Q, Chang KO, Saif LJ. The effects of simvastatin or interferon-α on infectivity of human norovirus using a gnotobiotic pig model for the study of antivirals. Plos One. 7: e41619. PMID 22911825 DOI: 10.1371/Journal.Pone.0041619  0.598
2012 Mandadapu SR, Weerawarna PM, Gunnam MR, Alliston KR, Lushington GH, Kim Y, Chang KO, Groutas WC. Potent inhibition of norovirus 3CL protease by peptidyl α-ketoamides and α-ketoheterocycles. Bioorganic & Medicinal Chemistry Letters. 22: 4820-6. PMID 22698498 DOI: 10.1016/J.Bmcl.2012.05.055  0.315
2012 Pokhrel L, Kim Y, Nguyen TD, Prior AM, Lu J, Chang KO, Hua DH. Synthesis and anti-norovirus activity of pyranobenzopyrone compounds. Bioorganic & Medicinal Chemistry Letters. 22: 3480-4. PMID 22513282 DOI: 10.1016/J.Bmcl.2012.03.084  0.314
2012 Kim Y, George D, Prior AM, Prasain K, Hao S, Le DD, Hua DH, Chang KO. Novel triacsin C analogs as potential antivirals against rotavirus infections. European Journal of Medicinal Chemistry. 50: 311-8. PMID 22365411 DOI: 10.1016/J.Ejmech.2012.02.010  0.375
2012 Dou D, Tiew KC, Mandadapu SR, Gunnam MR, Alliston KR, Kim Y, Chang KO, Groutas WC. Potent norovirus inhibitors based on the acyclic sulfamide scaffold. Bioorganic & Medicinal Chemistry. 20: 2111-8. PMID 22356738 DOI: 10.1016/J.Bmc.2012.01.030  0.351
2012 Chang KO, Takahashi D, Prakash O, Kim Y. Characterization and inhibition of norovirus proteases of genogroups I and II using a fluorescence resonance energy transfer assay. Virology. 423: 125-33. PMID 22200497 DOI: 10.1016/J.Virol.2011.12.002  0.37
2012 Dou D, He G, Mandadapu SR, Aravapalli S, Kim Y, Chang KO, Groutas WC. Inhibition of noroviruses by piperazine derivatives. Bioorganic & Medicinal Chemistry Letters. 22: 377-9. PMID 22119464 DOI: 10.1016/J.Bmcl.2011.10.122  0.334
2012 Thapa M, Kim Y, Desper J, Chang KO, Hua DH. Synthesis and antiviral activity of substituted quercetins. Bioorganic & Medicinal Chemistry Letters. 22: 353-6. PMID 22115591 DOI: 10.1016/J.Bmcl.2011.10.119  0.417
2012 Dou D, Mandadapu SR, Alliston KR, Kim Y, Chang KO, Groutas WC. Cyclosulfamide-based derivatives as inhibitors of noroviruses. European Journal of Medicinal Chemistry. 47: 59-64. PMID 22063754 DOI: 10.1016/J.Ejmech.2011.10.019  0.327
2012 Takahashi D, Kim Y, Chang KO, Anbanandam A, Prakash O. Backbone and side-chain ¹H, ¹⁵N, and ¹³C resonance assignments of Norwalk virus protease. Biomolecular Nmr Assignments. 6: 19-21. PMID 21647610 DOI: 10.1007/S12104-011-9316-3  0.374
2011 Kim Y, Chang KO. Inhibitory effects of bile acids and synthetic farnesoid X receptor agonists on rotavirus replication. Journal of Virology. 85: 12570-7. PMID 21957312 DOI: 10.1128/Jvi.05839-11  0.363
2011 Dou D, Tiew KC, He G, Mandadapu SR, Aravapalli S, Alliston KR, Kim Y, Chang KO, Groutas WC. Potent inhibition of Norwalk virus by cyclic sulfamide derivatives. Bioorganic & Medicinal Chemistry. 19: 5975-83. PMID 21925886 DOI: 10.1016/J.Bmc.2011.08.054  0.315
2011 Dou D, Mandadapu SR, Alliston KR, Kim Y, Chang KO, Groutas WC. Design and synthesis of inhibitors of noroviruses by scaffold hopping. Bioorganic & Medicinal Chemistry. 19: 5749-55. PMID 21893416 DOI: 10.1016/J.Bmc.2011.08.032  0.31
2011 Tiew KC, He G, Aravapalli S, Mandadapu SR, Gunnam MR, Alliston KR, Lushington GH, Kim Y, Chang KO, Groutas WC. Design, synthesis, and evaluation of inhibitors of Norwalk virus 3C protease. Bioorganic & Medicinal Chemistry Letters. 21: 5315-9. PMID 21802286 DOI: 10.1016/J.Bmcl.2011.07.016  0.386
2011 Kim Y, Thapa M, Hua DH, Chang KO. Biodegradable nanogels for oral delivery of interferon for norovirus infection. Antiviral Research. 89: 165-73. PMID 21144866 DOI: 10.1016/J.Antiviral.2010.11.016  0.315
2011 Takahashi D, Kim Y, Chang K, Anbanandam A, Prakash O. Solution Structure Determination of Norwalk Virus 3C-Like Cysteine Protease Biophysical Journal. 100: 605a-606a. DOI: 10.1016/J.Bpj.2010.12.3486  0.349
2010 Kim Y, Narayanan S, Chang KO. Inhibition of influenza virus replication by plant-derived isoquercetin. Antiviral Research. 88: 227-35. PMID 20826184 DOI: 10.1016/J.Antiviral.2010.08.016  0.376
2006 Park SJ, Jeong C, Yoon SS, Choy HE, Saif LJ, Park SH, Kim YJ, Jeong JH, Park SI, Kim HH, Lee BJ, Cho HS, Kim SK, Kang MI, Cho KO. Detection and characterization of bovine coronaviruses in fecal specimens of adult cattle with diarrhea during the warmer seasons. Journal of Clinical Microbiology. 44: 3178-88. PMID 16954245 DOI: 10.1128/Jcm.02667-05  0.397
2006 Park SH, Saif LJ, Jeong C, Lim GK, Park SI, Kim HH, Park SJ, Kim YJ, Jeong JH, Kang MI, Cho KO. Molecular characterization of novel G5 bovine rotavirus strains. Journal of Clinical Microbiology. 44: 4101-12. PMID 16928963 DOI: 10.1128/Jcm.01196-06  0.413
2004 Chang KO, Sosnovtsev SV, Belliot G, Kim Y, Saif LJ, Green KY. Bile acids are essential for porcine enteric calicivirus replication in association with down-regulation of signal transducer and activator of transcription 1. Proceedings of the National Academy of Sciences of the United States of America. 101: 8733-8. PMID 15161971 DOI: 10.1073/Pnas.0401126101  0.499
2004 Azevedo MS, Yuan L, Iosef C, Chang KO, Kim Y, Nguyen TV, Saif LJ. Magnitude of serum and intestinal antibody responses induced by sequential replicating and nonreplicating rotavirus vaccines in gnotobiotic pigs and correlation with protection. Clinical and Diagnostic Laboratory Immunology. 11: 12-20. PMID 14715539 DOI: 10.1128/Cdli.11.1.12-20.2004  0.618
2003 Nguyen TV, Iosef C, Jeong K, Kim Y, Chang KO, Lovgren-Bengtsson K, Morein B, Azevedo MS, Lewis P, Nielsen P, Yuan L, Saif LJ. Protection and antibody responses to oral priming by attenuated human rotavirus followed by oral boosting with 2/6-rotavirus-like particles with immunostimulating complexes in gnotobiotic pigs. Vaccine. 21: 4059-70. PMID 12922143 DOI: 10.1016/S0264-410X(03)00267-6  0.616
2002 Chang KO, Kim Y, Green KY, Saif LJ. Cell-culture propagation of porcine enteric calicivirus mediated by intestinal contents is dependent on the cyclic AMP signaling pathway. Virology. 304: 302-10. PMID 12504571 DOI: 10.1006/Viro.2002.1665  0.503
2002 Kim Y, Chang KO, Kim WY, Saif LJ. Production of hybrid double- or triple-layered virus-like particles of group A and C rotaviruses using a baculovirus expression system. Virology. 302: 1-8. PMID 12429511 DOI: 10.1006/Viro.2002.1610  0.497
2002 Iosef C, Van Nguyen T, Jeong Ki, Bengtsson K, Morein B, Kim Y, Chang KO, Azevedo MS, Yuan L, Nielsen P, Saif LJ. Systemic and intestinal antibody secreting cell responses and protection in gnotobiotic pigs immunized orally with attenuated Wa human rotavirus and Wa 2/6-rotavirus-like-particles associated with immunostimulating complexes. Vaccine. 20: 1741-53. PMID 11906761 DOI: 10.1016/S0264-410X(02)00031-2  0.627
2002 Kim Y, Nielsen PR, Hodgins D, Chang KO, Saif LJ. Lactogenic antibody responses in cows vaccinated with recombinant bovine rotavirus-like particles (VLPs) of two serotypes or inactivated bovine rotavirus vaccines. Vaccine. 20: 1248-58. PMID 11803088 DOI: 10.1016/S0264-410X(01)00404-2  0.525
2001 Yuan L, Iosef C, Azevedo MS, Kim Y, Qian Y, Geyer A, Nguyen TV, Chang KO, Saif LJ. Protective immunity and antibody-secreting cell responses elicited by combined oral attenuated Wa human rotavirus and intranasal Wa 2/6-VLPs with mutant Escherichia coli heat-labile toxin in gnotobiotic pigs. Journal of Virology. 75: 9229-38. PMID 11533185 DOI: 10.1128/Jvi.75.19.9229-9238.2001  0.633
1999 Chang KO, Kim YJ, Saif LJ. Comparisons of nucleotide and deduced amino acid sequences of NSP4 genes of virulent and attenuated pairs of group A and C rotaviruses. Virus Genes. 18: 229-33. PMID 10456791 DOI: 10.1023/A:1008068218966  0.432
1999 Kim Y, Chang KO, Straw B, Saif LJ. Characterization of group C rotaviruses associated with diarrhea outbreaks in feeder pigs. Journal of Clinical Microbiology. 37: 1484-8. PMID 10203510 DOI: 10.1128/Jcm.37.5.1484-1488.1999  0.491
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