John W. Daly - Publications

Affiliations: 
Laboratory of Bioorganic Chemistry NIDDK, Bethesda, MD, United States 
Area:
amphibian-derived alkaloids
Website:
https://pubs.acs.org/cen/news/86/i10/8610notw11.html

362 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Andriamaharavo NR, Garraffo HM, Saporito RA, Daly JW, Razafindrabe CR, Andriantsiferana M, Spande TF. Roughing it: a mantellid poison frog shows greater alkaloid diversity in some disturbed habitats. Journal of Natural Products. 73: 322-30. PMID 20178326 DOI: 10.1021/np900721r  0.72
2009 Ohtani M, Daly JW, Oka T. Co-existence of muscarinic and nicotinic receptors and their functional interaction in mouse Beta-TC6 cells. European Journal of Pharmacology. 604: 150-7. PMID 19109944 DOI: 10.1016/j.ejphar.2008.12.018  1
2009 Kem WR, Rocca J, Garraffo HM, Spande TF, Daly JW, Soti F. Synthesis and spectroscopic comparison of the eight methyl-2,3′-bipyridyls and identification of a hoplonemertine alkaloid as 3-methyl-2,3′-bipyridyl Heterocycles. 79: 1025-1041. DOI: 10.3987/COM-08-S(D)80  0.72
2009 Fitch RW, Spande TF, Garraffo HM, Chase RR, Clinedinst MA, Parkes DA, Reed R, Whittaker NF, Daly JW. Dioicine: A novel prenylated purine alkaloid from Gymnocladus dioicus Heterocycles. 79: 583-598. DOI: 10.3987/COM-08-S(D)19  0.72
2009 Zhou D, Toyooka N, Nemoto H, Yamaguchi K, Tsuneki H, Wada T, Sasaoka T, Sakai H, Tezuka Y, Kadota S, Jones TH, Garraffo HM, Spande TF, Daly JW. Synthesis, determination of the absolute stereochemistry, and evaluations at the nicotinic acetylcholine receptors of a hydroxyindolizidine alkaloid from the ant Myrmicaria melanogaster Heterocycles. 79: 565-571. DOI: 10.3987/COM-08-S(D)16  0.84
2009 Dumbacher JP, Menon GK, Daly JW. Skin as a toxin storage organ in the endemic new Guinean genus Pitohui Auk. 126: 520-530. DOI: 10.1525/auk.2009.08230  0.84
2008 Nelson A, Garraffo HM, Spande TF, Daly JW, Stevenson PJ. Facile synthesis of two diastereomeric indolizidines corresponding to the postulated structure of alkaloid 5,9E-259B from a Bufonid toad (Melanophryniscus). Beilstein Journal of Organic Chemistry. 4: 6. PMID 18208586 DOI: 10.1186/1860-5397-4-6  0.84
2008 Daly JW, Garraffo HM, Spande TF, Giddings LA, Saporito RA, Vieites DR, Vences M. Individual and geographic variation of skin alkaloids in three species of Madagascan poison frogs (Mantella). Journal of Chemical Ecology. 34: 252-79. PMID 18196341 DOI: 10.1007/s10886-007-9396-9  0.84
2008 Saporito RA, Donnelly MA, Norton RA, Garraffo HM, Spande TF, Daly JW. Oribatid mites as a major dietary source for alkaloids in poison frogs (Proceedings of the National Academy of Sciences of the United States of America (2007) 104, 21, (8885-8890) DOI: 10.1073/pnas.0702851104) Proceedings of the National Academy of Sciences of the United States of America. 105: 17587. DOI: 10.1073/pnas.0808595105  0.72
2008 Toyooka N, Zhou D, Kobayashi S, Tsuneki H, Wada T, Sakai H, Nemoto H, Sasaoka T, Tezuka Y, Subehan, Kadota S, Garraffo HM, Spande TF, Daly JW. Syntheses of the proposed structures of poison-frog alkaloids 179 and 207E and their inhibitory effects on neuronal nicotinic acetylcholine receptors Synlett. 0061-0064. DOI: 10.1055/s-2007-1000831  0.32
2007 Toyooka N, Zhou D, Nemoto H, Garraffo HM, Spande TF, Daly JW. Flexible synthetic routes to poison-frog alkaloids of the 5,8-disubstituted indolizidine-class I: synthesis of common lactam chiral building blocks and application to the synthesis of (-)-203A, (-)-205A, and (-)-219F. Beilstein Journal of Organic Chemistry. 3: 29. PMID 17903239 DOI: 10.1186/1860-5397-3-30  0.84
2007 Toyooka N, Kobayashi S, Zhou D, Tsuneki H, Wada T, Sakai H, Nemoto H, Sasaoka T, Garraffo HM, Spande TF, Daly JW. Synthesis of poison-frog alkaloids 233A, 235U, and 251AA and their inhibitory effects on neuronal nicotinic acetylcholine receptors. Bioorganic & Medicinal Chemistry Letters. 17: 5872-5. PMID 17827002 DOI: 10.1016/j.bmcl.2007.08.045  0.32
2007 Saporito RA, Donnelly MA, Jain P, Martin Garraffo H, Spande TF, Daly JW. Spatial and temporal patterns of alkaloid variation in the poison frog Oophaga pumilio in Costa Rica and Panama over 30 years. Toxicon : Official Journal of the International Society On Toxinology. 50: 757-78. PMID 17706737 DOI: 10.1016/j.toxicon.2007.06.022  0.84
2007 Daly JW. Caffeine analogs: biomedical impact. Cellular and Molecular Life Sciences : Cmls. 64: 2153-69. PMID 17514358 DOI: 10.1007/s00018-007-7051-9  0.84
2007 Saporito RA, Donnelly MA, Norton RA, Garraffo HM, Spande TF, Daly JW. Oribatid mites as a major dietary source for alkaloids in poison frogs. Proceedings of the National Academy of Sciences of the United States of America. 104: 8885-90. PMID 17502597 DOI: 10.1073/pnas.0702851104  0.84
2007 Daly JW, Wilham JM, Spande TF, Garraffo HM, Gil RR, Silva GL, Vaira M. Alkaloids in bufonid toads (melanophryniscus): temporal and geographic determinants for two argentinian species. Journal of Chemical Ecology. 33: 871-87. PMID 17333373 DOI: 10.1007/s10886-007-9261-x  0.84
2006 Weldon PJ, Kramer M, Gordon S, Spande TF, Daly JW. A common pumiliotoxin from poison frogs exhibits enantioselective toxicity against mosquitoes. Proceedings of the National Academy of Sciences of the United States of America. 103: 17818-21. PMID 17095598 DOI: 10.1073/pnas.0608646103  0.84
2006 Ohtani M, Oka T, Badyuk M, Xiao Y, Kellar KJ, Daly JW. Mouse beta-TC6 insulinoma cells: high expression of functional alpha3beta4 nicotinic receptors mediating membrane potential, intracellular calcium, and insulin release. Molecular Pharmacology. 69: 899-907. PMID 16332988 DOI: 10.1124/mol.105.014902  0.84
2006 Toyooka N, Kawasaki M, Nemoto H, Daly JW, Spande TF, Garraffo HM. Enantioselective synthesis of poison-frog alkaloid 237d and determination of absolute stereochemistry Heterocycles. 68: 1317. DOI: 10.3987/COM-04-10269  0.72
2006 Toyooka N, Dejun Z, Nemoto H, Garraffo HM, Spande TF, Daly JW. The enantioselective synthesis of poison-frog alkaloids (-)-203A, (-)-209B, (-)-231C, (-)-233D, and (-)-235B″ Tetrahedron Letters. 47: 577-580. DOI: 10.1016/j.tetlet.2005.11.047  0.84
2006 Toyooka N, Dejun Z, Nemoto H, Garraffo HM, Spande TF, Daly JW. Enantioselective syntheses of poison-frog alkaloids: 219F and 221I and an epimer of 193E Tetrahedron Letters. 47: 581-582. DOI: 10.1016/j.tetlet.2005.11.046  0.72
2006 Daly JW, Camerini-Otero CS. Imidazole-induced elevations of intracellular calcium in HL-60 Cells: Effect of inhibition of phospholipase C by the steroidal maleimide U73122 Drug Development Research. 67: 519-534. DOI: 10.1002/ddr.20111  0.84
2005 Macfoy C, Danosus D, Sandit R, Jones TH, Garraffo HM, Spande TF, Daly JW. Alkaloids of anuran skin: antimicrobial function? Zeitschrift FüR Naturforschung. C, Journal of Biosciences. 60: 932-7. PMID 16402556  0.84
2005 Andriamaharavo NR, Andriantsiferana M, Stevenson PA, O'mahony G, Yeh HJ, Kaneko T, Garraffo HM, Spande TF, Daly JW. A revised structure for alkaloid 235C isolated from skin extracts of mantellid (Mantella) frogs of Madagascar. Journal of Natural Products. 68: 1743-8. PMID 16378366 DOI: 10.1021/np058089f  0.84
2005 Daly JW, Spande TF, Garraffo HM. Alkaloids from amphibian skin: a tabulation of over eight-hundred compounds. Journal of Natural Products. 68: 1556-75. PMID 16252926 DOI: 10.1021/np0580560  0.84
2005 Daly JW. Nicotinic agonists, antagonists, and modulators from natural sources. Cellular and Molecular Neurobiology. 25: 513-52. PMID 16075378 DOI: 10.1007/s10571-005-3968-4  0.84
2005 Fitch RW, Daly JW. Phosphorimaging detection and quantitation for isotopic ion flux assays. Analytical Biochemistry. 342: 260-70. PMID 15950910 DOI: 10.1016/j.ab.2005.04.041  0.68
2005 Fitch RW, Kaneko Y, Klaperski P, Daly JW, Seitz G, Gündisch D. Halogenated and isosteric cytisine derivatives with increased affinity and functional activity at nicotinic acetylcholine receptors. Bioorganic & Medicinal Chemistry Letters. 15: 1221-4. PMID 15686946 DOI: 10.1016/j.bmcl.2004.11.073  0.84
2005 Toyooka N, Nemoto H, Kawasaki M, Martin Garraffo H, Spande TF, Daly JW. Enantioselective syntheses of two 5, 9E diastereomers of 223V, an alkaloid from the poison frog Dendrobates pumilio Tetrahedron. 61: 1187-1198. DOI: 10.1016/j.tet.2004.11.060  0.72
2004 Daly JW, Noimai N, Kongkathip B, Kongkathip N, Wilham JM, Garraffo HM, Kaneko T, Spande TF, Nimit Y, Nabhitabhata J, Chan-Ard T. Biologically active substances from amphibians: preliminary studies on anurans from twenty-one genera of Thailand. Toxicon : Official Journal of the International Society On Toxinology. 44: 805-15. PMID 15530960 DOI: 10.1016/j.toxicon.2004.08.016  0.84
2004 Dumbacher JP, Wako A, Derrickson SR, Samuelson A, Spande TF, Daly JW. Melyrid beetles (Choresine): a putative source for the batrachotoxin alkaloids found in poison-dart frogs and toxic passerine birds. Proceedings of the National Academy of Sciences of the United States of America. 101: 15857-60. PMID 15520388 DOI: 10.1073/pnas.0407197101  0.84
2004 Daly JW. Marine toxins and nonmarine toxins: convergence or symbiotic organisms? Journal of Natural Products. 67: 1211-5. PMID 15332834 DOI: 10.1021/np040016t  0.84
2004 Saporito RA, Garraffo HM, Donnelly MA, Edwards AL, Longino JT, Daly JW. Formicine ants: An arthropod source for the pumiliotoxin alkaloids of dendrobatid poison frogs. Proceedings of the National Academy of Sciences of the United States of America. 101: 8045-50. PMID 15128938 DOI: 10.1073/pnas.0402365101  0.84
2004 Yotsu-Yamashita M, Kim YH, Dudley SC, Choudhary G, Pfahnl A, Oshima Y, Daly JW. The structure of zetekitoxin AB, a saxitoxin analog from the Panamanian golden frog Atelopus zeteki: a potent sodium-channel blocker. Proceedings of the National Academy of Sciences of the United States of America. 101: 4346-51. PMID 15070720 DOI: 10.1073/pnas.0400368101  0.32
2004 Ye S, Rezende MM, Deng WP, Herbert B, Daly JW, Johnson RA, Kirk KL. Synthesis of 2',5'-dideoxy-2-fluoroadenosine and 2',5'-dideoxy-2,5'-difluoroadenosine: potent P-site inhibitors of adenylyl cyclase. Journal of Medicinal Chemistry. 47: 1207-13. PMID 14971900 DOI: 10.1021/jm0303599  0.32
2004 Fitch RW, Pei XF, Kaneko Y, Gupta T, Shi D, Federova I, Daly JW. Homoepiboxidines: further potent agonists for nicotinic receptors. Bioorganic & Medicinal Chemistry. 12: 179-90. PMID 14697783 DOI: 10.1016/j.bmc.2003.10.015  0.84
2003 Saporito RA, Donnelly MA, Hoffman RL, Garraffo HM, Daly JW. A siphonotid millipede (Rhinotus) as the source of spiropyrrolizidine oximes of dendrobatid frogs. Journal of Chemical Ecology. 29: 2781-6. PMID 14969363 DOI: 10.1023/B:JOEC.0000008065.28364.a0  0.84
2003 Sunthitikawinsakul A, Kongkathip N, Kongkathip B, Phonnakhu S, Daly JW, Spande TF, Nimit Y, Napaswat C, Kasisit J, Yoosook C. Anti-HIV-1 limonoid: first isolation from Clausena excavata. Phytotherapy Research : Ptr. 17: 1101-3. PMID 14595596 DOI: 10.1002/ptr.1381  0.64
2003 Fitch RW, Garraffo HM, Spande TF, Yeh HJ, Daly JW. Bioassay-guided isolation of epiquinamide, a novel quinolizidine alkaloid and nicotinic agonist from an Ecuadoran poison frog, Epipedobates tricolor. Journal of Natural Products. 66: 1345-50. PMID 14575435 DOI: 10.1021/np030306u  0.84
2003 Daly JW, Garraffo HM, Spande TF, Clark VC, Ma J, Ziffer H, Cover JF. Evidence for an enantioselective pumiliotoxin 7-hydroxylase in dendrobatid poison frogs of the genus Dendrobates. Proceedings of the National Academy of Sciences of the United States of America. 100: 11092-7. PMID 12960405 DOI: 10.1073/pnas.1834430100  0.84
2003 Shi D, Padgett WL, Daly JW. Caffeine analogs: effects on ryanodine-sensitive calcium-release channels and GABAA receptors. Cellular and Molecular Neurobiology. 23: 331-47. PMID 12825831 DOI: 10.1023/A:1023688604792  0.84
2003 Fitch RW, Xiao Y, Kellar KJ, Daly JW. Membrane potential fluorescence: a rapid and highly sensitive assay for nicotinic receptor channel function. Proceedings of the National Academy of Sciences of the United States of America. 100: 4909-14. PMID 12657731 DOI: 10.1073/pnas.0630641100  0.84
2003 Sunthitikawinsakul A, Kongkathip N, Kongkathip B, Phonnakhu S, Daly JW, Spande TF, Nimit Y, Rochanaruangrai S. Coumarins and carbazoles from Clausena excavata exhibited antimycobacterial and antifungal activities. Planta Medica. 69: 155-7. PMID 12624822 DOI: 10.1055/s-2003-37716  0.84
2003 Daly JW. Ernest Guenther award in chemistry of natural products. Amphibian skin: a remarkable source of biologically active arthropod alkaloids. Journal of Medicinal Chemistry. 46: 445-52. PMID 12570366 DOI: 10.1021/jm0204845  0.84
2003 Harper JL, Camerini-Otero CS, Li AH, Kim SA, Jacobson KA, Daly JW. Dihydropyridines as inhibitors of capacitative calcium entry in leukemic HL-60 cells. Biochemical Pharmacology. 65: 329-38. PMID 12527326 DOI: 10.1016/S0006-2952(02)01488-0  0.84
2002 Sei Y, Brandom BW, Bina S, Hosoi E, Gallagher KL, Wyre HW, Pudimat PA, Holman SJ, Venzon DJ, Daly JW, Muldoon S. Patients with malignant hyperthermia demonstrate an altered calcium control mechanism in B lymphocytes. Anesthesiology. 97: 1052-8. PMID 12411786 DOI: 10.1097/00000542-200211000-00005  0.44
2002 Daly JW, Kaneko T, Wilham J, Garraffo HM, Spande TF, Espinosa A, Donnelly MA. Bioactive alkaloids of frog skin: combinatorial bioprospecting reveals that pumiliotoxins have an arthropod source. Proceedings of the National Academy of Sciences of the United States of America. 99: 13996-4001. PMID 12381780 DOI: 10.1073/pnas.222551599  0.84
2002 Müller CE, Thorand M, Qurishi R, Diekmann M, Jacobson KA, Padgett WL, Daly JW. Imidazo[2,1-i]purin-5-ones and related tricyclic water-soluble purine derivatives: potent A(2A)- and A(3)-adenosine receptor antagonists. Journal of Medicinal Chemistry. 45: 3440-50. PMID 12139454 DOI: 10.1021/jm011093d  0.84
2002 Flowers A, Onwueme K, Creveling CR, Daly JW. Reserpine: interactions with batrachotoxin and brevetoxin sites on voltage-dependent sodium channels. Cellular and Molecular Neurobiology. 22: 1-12. PMID 12064513 DOI: 10.1023/A:1015301610349  0.32
2002 Toyooka N, Fukutome A, Nemoto H, Daly JW, Spande TF, Garraffo HM, Kaneko T. Synthesis of alkaloid 223A and a structural revision. Organic Letters. 4: 1715-7. PMID 12000281 DOI: 10.1021/ol025775m  0.84
2002 Smith BP, Tyler MJ, Kaneko T, Garraffo HM, Spande TF, Daly JW. Evidence for biosynthesis of pseudophrynamine alkaloids by an Australian myobatrachid frog (pseudophryne) and for sequestration of dietary pumiliotoxins. Journal of Natural Products. 65: 439-47. PMID 11975476 DOI: 10.1021/np010506a  0.84
2002 Hayallah AM, Sandoval-Ramírez J, Reith U, Schobert U, Preiss B, Schumacher B, Daly JW, Müller CE. 1,8-disubstituted xanthine derivatives: synthesis of potent A2B-selective adenosine receptor antagonists. Journal of Medicinal Chemistry. 45: 1500-10. PMID 11906291 DOI: 10.1021/jm011049y  0.84
2001 Garraffo HM, Jain P, Spande TF, Daly JW, Jones TH, Smith LJ, Zottig VE. Structure of alkaloid 275A, a novel 1-azabicyclo[5.3.0]decane from a dendrobatid frog, Dendrobates lehmanni: synthesis of the tetrahydrodiastereomers. Journal of Natural Products. 64: 421-7. PMID 11325220 DOI: 10.1021/np0005098  0.84
2001 Sei Y, Gallagher KL, Daly JW. Multiple effects of caffeine on Ca2+ release and influx in human B lymphocytes. Cell Calcium. 29: 149-60. PMID 11162852 DOI: 10.1054/ceca.2000.0175  0.68
2000 Daly JW, Gupta TH, Padgett WL, Pei XF. 6beta-Acyloxy(nor)tropanes: affinities for antagonist/agonist binding sites on transfected and native muscarinic receptors. Journal of Medicinal Chemistry. 43: 2514-22. PMID 10891110 DOI: 10.1021/jm9904001  0.64
2000 Daly JW. Alkylxanthines as research tools. Journal of the Autonomic Nervous System. 81: 44-52. PMID 10869699 DOI: 10.1016/S0165-1838(00)00110-7  0.84
2000 Shin Y, Daly JW, Choi OH. Diverse effects of sphingosine on calcium mobilization and influx in differentiated HL-60 cells. Cell Calcium. 27: 269-80. PMID 10859593 DOI: 10.1054/ceca.2000.0118  0.64
2000 Daly JW, Garraffo HM, Spande TF, Decker MW, Sullivan JP, Williams M. Alkaloids from frog skin: the discovery of epibatidine and the potential for developing novel non-opioid analgesics. Natural Product Reports. 17: 131-5. PMID 10821107 DOI: 10.1039/a900728h  0.84
2000 Lu SF, Herbert B, Haufe G, Laue KW, Padgett WL, Oshunleti O, Daly JW, Kirk KL. Syntheses of (R)- and (S)-2- and 6-fluoronorepinephrine and (R)- and (S)-2- and 6-fluoroepinephrine: effect of stereochemistry on fluorine-induced adrenergic selectivities. Journal of Medicinal Chemistry. 43: 1611-9. PMID 10780918 DOI: 10.1021/jm990599h  0.32
2000 Jiang X, Lim LY, Daly JW, Li AH, Jacobson KA, Roberge M. Structure-activity relationships for G2 checkpoint inhibition by caffeine analogs. International Journal of Oncology. 16: 971-8. PMID 10762633 DOI: 10.3892/ijo.16.5.971  0.48
1999 Shi D, Daly JW. Chronic effects of xanthines on levels of central receptors in mice. Cellular and Molecular Neurobiology. 19: 719-32. PMID 10456233 DOI: 10.1023/A:1006901005925  0.84
1999 Garraffo HM, Spande TF, Jones TH, Daly JW. Ammonia chemical ionization tandem mass spectrometry in structure determination of alkaloids. I. Pyrrolidines, piperidines, decahydroquinolines, pyrrolizidines, indolizidines, quinolizidines and an azabicyclo[5.3.0]decane. Rapid Communications in Mass Spectrometry : Rcm. 13: 1553-63. PMID 10421897 DOI: 10.1002/(SICI)1097-0231(19990815)13:15<1553::AID-RCM658>3.0.CO;2-U  0.84
1999 Spande TF, Jain P, Garraffo HM, Pannell LK, Yeh HJC, Daly JW, Fukumoto S, Imamura K, Tokuyama T, Torres JA, Snelling RR, Jones TH. Occurrence and significance of decahydroquinolines from dendrobatid poison frogs and a myrmicine ant: use of 1H and 13C NMR in their conformational analysis Journal of Natural Products. 62: 5-21. PMID 9917275 DOI: 10.1021/np980298v  0.72
1999 Daly JW, Martin Garraffo H, Spande TF. Chapter One Alkaloids from amphibian skins Alkaloids: Chemical and Biological Perspectives. 13: 1-161. DOI: 10.1016/S0735-8210(99)80024-7  0.72
1999 Kirk KL, Herbert B, Lu SF, Jayachandran B, Padgett WL, Olufunke O, Daly JW, Haufe G, Laue KW. Chemical and biochemical approaches to the enantiomers of chiral fluorinated catecholamines and amino acids Acs Symposium Series. 746: 194-209.  0.6
1999 Jain P, Spande TF, Garraffo HM, Daly JW. The isolation and structure of pumiliotoxin 341A: A novel cyclic ether from the frog Epipedobates tricolor Heterocycles. 50: 903-912.  0.84
1999 Jones TH, Gorman JST, Snelling RR, Delabie JHC, Blum MS, Garraffo HM, Jain P, Daly JW, Spande TF. Further alkaloids common to ants and frogs: Decahydroquinolines and a quinolizidine Journal of Chemical Ecology. 25: 1179-1193.  0.84
1998 Park KS, Hoffmann C, Kim HO, Padgett WL, Daly JW, Brambilla R, Motta C, Abbracchio MP, Jacobson KA. Activation and Desensitization of Rat A3-Adenosine Receptors by Selective Adenosine Derivatives and Xanthine-7-Ribosides. Drug Development Research. 44: 97-105. PMID 23487508 DOI: 10.1002/(SICI)1098-2299(199806/07)44:2/3<97::AID-DDR7>3.0.CO;2-5  0.84
1998 Daly JW, Holmén J, Fredholm BB. [Is caffeine addictive? The most widely used psychoactive substance in the world affects same parts of the brain as cocaine]. LäKartidningen. 95: 5878-83. PMID 9889511  0.68
1998 Daly JW, Fredholm BB. Caffeine--an atypical drug of dependence. Drug and Alcohol Dependence. 51: 199-206. PMID 9716941 DOI: 10.1016/S0376-8716(98)00077-5  0.68
1998 Pei XF, Gupta TH, Badio B, Padgett WL, Daly JW. 6beta-Acetoxynortropane: a potent muscarinic agonist with apparent selectivity toward M2-receptors. Journal of Medicinal Chemistry. 41: 2047-55. PMID 9622546 DOI: 10.1021/jm9705115  0.6
1998 Daly JW. Thirty years of discovering arthropod alkaloids in amphibian skin. Journal of Natural Products. 61: 162-72. PMID 9461669 DOI: 10.1021/np970460e  0.72
1998 Daly JW. Chapter 4 The Nature and Origin of Amphibian Alkaloids Alkaloids: Chemistry and Biology. 50: 141-169. DOI: 10.1016/S1099-4831(08)60042-5  0.84
1998 Tokuyama T, Garraffo HM, Spande TF, Daly JW. A revised structure for alkaloid 205B, a novel 8B-azaacenaphthylene from a poison frog Anales Des La Asociacion Quimica Argentina. 86: 291-298.  0.72
1998 Tokuyama T, Shimada A, Martin Garraffo H, Spande TF, Daly JW. The isolation and structure of the novel cis-fused indolizidine 249h from frog skin: CIS- vs. trans-fused indolizidines distinguished by NMR Heterocycles. 49: 427-436.  0.84
1997 Daly JW, Shi D, Padgett WL, Ji XD, Jacobson KA. Riboflavin: Inhibitory Effects on Receptors, G-Proteins, and Adenylate Cyclase. Drug Development Research. 42: 98-108. PMID 22772360 DOI: 10.1002/(SICI)1098-2299(199710)42:2<98::AID-DDR6>3.0.CO;2-K  0.84
1997 Harper JL, Shin Y, Daly JW. Loperamide: a positive modulator for store-operated calcium channels? Proceedings of the National Academy of Sciences of the United States of America. 94: 14912-7. PMID 9405713 DOI: 10.1073/pnas.94.26.14912  0.84
1997 Daly JW, Garraffo HM, Hall GS, Cover JF. Absence of skin alkaloids in captive-raised Madagascan mantelline frogs (Mantella) and sequestration of dietary alkaloids. Toxicon : Official Journal of the International Society On Toxinology. 35: 1131-5. PMID 9248011 DOI: 10.1016/S0041-0101(96)00212-7  0.72
1997 Daly JW, Padgett WL, Saunders RL, Cover JF. Absence of tetrodotoxins in a captive-raised riparian frog, Atelopus varius. Toxicon : Official Journal of the International Society On Toxinology. 35: 705-9. PMID 9203295 DOI: 10.1016/S0041-0101(96)00165-1  0.6
1997 Badio B, Garraffo HM, Padgett WL, Greig NH, Daly JW. Pseudophrynaminol: a potent noncompetitive blocker of nicotinic receptor-channels. Biochemical Pharmacology. 53: 671-6. PMID 9113086 DOI: 10.1016/S0006-2952(96)00878-7  0.6
1997 Badio B, Garraffo HM, Plummer CV, Padgett WL, Daly JW. Synthesis and nicotinic activity of epiboxidine: an isoxazole analogue of epibatidine. European Journal of Pharmacology. 321: 189-94. PMID 9063687 DOI: 10.1016/S0014-2999(96)00939-9  1
1997 Badio B, Padgett WL, Daly JW. Ibogaine: a potent noncompetitive blocker of ganglionic/neuronal nicotinic receptors. Molecular Pharmacology. 51: 1-5. PMID 9016339  0.32
1997 Toyooka N, Tanaka K, Momose T, Daly JW, Garraffo HM. Highly stereoselective construction of trans(2,3)-cis(2,6)- Trisubstituted piperidines: An application to the chiral synthesis of dendrobates alkaloids Tetrahedron. 53: 9553-9574. DOI: 10.1016/S0040-4020(97)00641-8  0.72
1997 Shi D, Padgett WL, Hutchinson KD, Moore SP, Daly JW. Pyrazolopyridines: Effect of structural alterations on activity at adenosine- and GABA(A)-receptors Drug Development Research. 42: 41-56. DOI: 10.1002/(SICI)1098-2299(199709)42:1<41::AID-DDR4>3.0.CO;2-R  1
1996 Siddiqi SM, Ji XD, Melman N, Olah ME, Jain R, Evans P, Glashofer M, Padgett WL, Cohen LA, Daly JW, Stiles GL, Jacobson KA. A SURVEY OF NONXANTHINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS. Nucleosides & Nucleotides. 15: 693-717. PMID 27043138 DOI: 10.1080/07328319608002416  0.84
1996 Shin Y, Daly JW, Jacobson KA. Activation of Phosphoinositide Breakdown and Elevation of Intracellular Calcium in a Rat RBL-2H3 Mast Cell Line by Adenosine Analogs: Involvement of A(3)-Adenosine Receptors? Drug Development Research. 39: 36-46. PMID 23087534  0.84
1996 Jain P, Garraffo HM, Yeh HJ, Spande TF, Daly JW, Andriamaharavo NR, Andriantsiferana M. A 1,4-disubstituted quinolizidine from a Madagascan mantelline frog (Mantella). Journal of Natural Products. 59: 1174-8. PMID 8988603 DOI: 10.1021/np9605100  0.72
1996 Jacobson KA, von Lubitz DK, Daly JW, Fredholm BB. Adenosine receptor ligands: differences with acute versus chronic treatment. Trends in Pharmacological Sciences. 17: 108-13. PMID 8936347 DOI: 10.1016/0165-6147(96)10002-X  0.84
1996 Badio B, Shi D, Shin Y, Hutchinson KD, Padgett WL, Daly JW. Spiropyrrolizidines: a new class of blockers of nicotinic receptors. Biochemical Pharmacology. 52: 933-9. PMID 8781513 DOI: 10.1016/0006-2952(96)00464-9  1
1996 van Rhee AM, Siddiqi SM, Melman N, Shi D, Padgett WL, Daly JW, Jacobson KA. Tetrahydrobenzothiophenone derivatives as a novel class of adenosine receptor antagonists. Journal of Medicinal Chemistry. 39: 398-406. PMID 8558508 DOI: 10.1021/jm9504823  0.84
1996 Shin Y, Daly JW, Jacobson KA. Activation of phosphoinositide breakdown and elevation of intracellular calcium in a rat RBL-2H3 mast cell line by adenosine analogs: Involvement of A3-adenosine receptors? Drug Development Research. 39: 36-46. DOI: 10.1002/(SICI)1098-2299(19960901)39:1<36::AID-DDR5>3.0.CO;2-L  0.84
1996 Nie JY, Shi D, Daly JW, Kirk KL. Synthesis of fluorodopamines: Effect of aryl fluoro substituents on affinities for adrenergic and dopaminergic receptors Medicinal Chemistry Research. 6: 318-332.  0.84
1996 Siddiqi SM, Ji XD, Melman N, Olah ME, Jain R, Evans P, Glashofer M, Padgett WL, Cohen LA, Daly JW, Stiles GL, Jacobson KA. A survey of nonxanthine derivatives as adenosine receptor ligands Nucleosides and Nucleotides. 15: 693-717.  0.84
1995 Moni RW, Romero FS, Daly JW. The amphiphilic peptide adenoregulin enhances agonist binding to A1-adenosine receptors and [35S]GTP gamma S to brain membranes. Cellular and Molecular Neurobiology. 15: 465-93. PMID 8565049 DOI: 10.1007/BF02071881  0.6
1995 Daly JW. The chemistry of poisons in amphibian skin. Proceedings of the National Academy of Sciences of the United States of America. 92: 9-13. PMID 7816854 DOI: 10.1073/pnas.92.1.9  0.84
1995 Von Lubitz DK, Kim J, Beenhakker M, Carter MF, Lin RC, Meshulam Y, Daly JW, Shi D, Zhou LM, Jacobson KA. Chronic NMDA receptor stimulation: therapeutic implications of its effect on adenosine A1 receptors. European Journal of Pharmacology. 283: 185-92. PMID 7498308 DOI: 10.1016/0014-2999(95)00338-L  1
1995 Daly JW, Lueders J, Padgett WL, Shin Y, Gusovsky F. Maitotoxin-elicited calcium influx in cultured cells. Effect of calcium-channel blockers. Biochemical Pharmacology. 50: 1187-97. PMID 7488233 DOI: 10.1016/0006-2952(95)00257-Z  0.64
1995 Badio B, Shi D, Garraffo M, Daly JW. Antinociceptive effects of the alkaloid epibatidine: Further studies on involvement of nicotinic receptors Drug Development Research. 36: 46-59. DOI: 10.1002/ddr.430360108  0.64
1994 Daly JW, Shi D, Nikodijevic O, Jacobson KA. The role of adenosine receptors in the central action of caffeine. Pharmacopsychoecologia. 7: 201-213. PMID 25821357  0.84
1994 Daly JW, Martin Garraffo H, Spande TF, Jaramillo C, Stanley Rand A. Dietary source for skin alkaloids of poison frogs (Dendrobatidae)? Journal of Chemical Ecology. 20: 943-55. PMID 24242207 DOI: 10.1007/BF02059589  0.84
1994 Badio B, Daly JW. Epibatidine, a potent analgetic and nicotinic agonist. Molecular Pharmacology. 45: 563-9. PMID 8183234  0.84
1994 Brackett LE, Daly JW. Functional characterization of the A2b adenosine receptor in NIH 3T3 fibroblasts. Biochemical Pharmacology. 47: 801-14. PMID 8135856 DOI: 10.1016/0006-2952(94)90480-4  0.32
1994 Daly JW, Gusovsky F, Myers CW, Yotsu-Yamashita M, Yasumoto T. First occurrence of tetrodotoxin in a dendrobatid frog (Colostethus inguinalis), with further reports for the bufonid genus Atelopus. Toxicon : Official Journal of the International Society On Toxinology. 32: 279-85. PMID 8016850 DOI: 10.1016/0041-0101(94)90081-7  0.72
1994 Cristalli G, Vittori S, Thompson RD, Padgett WL, Shi D, Daly JW, Olsson RA. Inhibition of platelet aggregation by adenosine receptor agonists. Naunyn-Schmiedeberg's Archives of Pharmacology. 349: 644-50. PMID 7969516 DOI: 10.1007/PL00004904  0.84
1994 Nikodijevic B, Sei Y, Shin Y, Daly JW. Effects of ATP and UTP in pheochromocytoma PC12 cells: evidence for the presence of three P2 receptors, only one of which subserves stimulation of norepinephrine release. Cellular and Molecular Neurobiology. 14: 27-47. PMID 7954659 DOI: 10.1007/BF02088587  0.72
1994 Daly JW, Shi D, Wong V, Nikodijevic O. Chronic effects of ethanol on central adenosine function of mice. Brain Research. 650: 153-6. PMID 7953667 DOI: 10.1016/0006-8993(94)90219-4  0.68
1994 Daly JW, Secunda SI, Garraffo HM, Spande TF, Wisnieski A, Cover JF. An uptake system for dietary alkaloids in poison frogs (Dendrobatidae). Toxicon : Official Journal of the International Society On Toxinology. 32: 657-63. PMID 7940573 DOI: 10.1016/0041-0101(94)90335-2  0.84
1994 Fredholm BB, Abbracchio MP, Burnstock G, Daly JW, Harden TK, Jacobson KA, Leff P, Williams M. Nomenclature and classification of purinoceptors. Pharmacological Reviews. 46: 143-56. PMID 7938164  1
1994 Shin Y, Moni RW, Lueders JE, Daly JW. Effects of the amphiphilic peptides mastoparan and adenoregulin on receptor binding, G proteins, phosphoinositide breakdown, cyclic AMP generation, and calcium influx. Cellular and Molecular Neurobiology. 14: 133-57. PMID 7842473 DOI: 10.1007/BF02090781  0.84
1994 Shi D, Nikodijević O, Jacobson KA, Daly JW. Effects of chronic caffeine on adenosine, dopamine and acetylcholine systems in mice. Archives Internationales De Pharmacodynamie Et De ThéRapie. 328: 261-87. PMID 7625882  0.48
1994 Dumbacher JP, Daly JW. Symposium: Chemical defense in birds Journal of Ornithology. 135: 407-410. DOI: 10.1007/BF01639984  0.84
1993 Jacobson KA, Nikodijević O, Padgett WL, Gallo-Rodriguez C, Maillard M, Daly JW. 8-(3-Chlorostyryl)caffeine (CSC) is a selective A2-adenosine antagonist in vitro and in vivo. Febs Letters. 323: 141-4. PMID 8495727 DOI: 10.1016/0014-5793(93)81466-D  1
1993 Garraffo HM, Spande TF, Daly JW, Baldessari A, Gros EG. Alkaloids from bufonid toads (Melanophryniscus): decahydroquinolines, pumiliotoxins and homopumiliotoxins, indolizidines, pyrrolizidines, and quinolizidines. Journal of Natural Products. 56: 357-73. PMID 8482947  0.72
1993 Daly JW, Padgett WL, Secunda SI, Thompson RD, Olsson RA. Structure-activity relationships for 2-substituted adenosines at A1 and A2 adenosine receptors. Pharmacology. 46: 91-100. PMID 8441759 DOI: 10.1159/000139033  1
1993 Glendinning JI. Pitohui: how toxic and to whom? Science (New York, N.Y.). 259: 582-3. PMID 8430299  0.84
1993 Jacobson KA, Shi D, Gallo-Rodriguez C, Manning M, Müller C, Daly JW, Neumeyer JL, Kiriasis L, Pfleiderer W. Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors. Journal of Medicinal Chemistry. 36: 2639-44. PMID 8410976  0.6
1993 Jacobson KA, Nikodijević O, Shi D, Gallo-Rodriguez C, Olah ME, Stiles GL, Daly JW. A role for central A3-adenosine receptors. Mediation of behavioral depressant effects. Febs Letters. 336: 57-60. PMID 8262217 DOI: 10.1016/0014-5793(93)81608-3  0.68
1993 Chen GT, King M, Gusovsky F, Creveling CR, Daly JW, Chen BH, Nie JY, Kirk KL. Syntheses of 2,5- and 2,6-difluoronorepinephrine, 2,5-difluoroepinephrine, and 2,6-difluorophenylephrine: effect of disubstitution with fluorine on adrenergic activity. Journal of Medicinal Chemistry. 36: 3947-55. PMID 8254623  1
1993 Müller CE, Daly JW. Stimulation of calcium release by caffeine analogs in pheochromocytoma cells. Biochemical Pharmacology. 46: 1825-9. PMID 8250969 DOI: 10.1016/0006-2952(93)90589-O  0.6
1993 Shi D, Nikodijević O, Jacobson KA, Daly JW. Chronic caffeine alters the density of adenosine, adrenergic, cholinergic, GABA, and serotonin receptors and calcium channels in mouse brain. Cellular and Molecular Neurobiology. 13: 247-61. PMID 8242688 DOI: 10.1007/BF00733753  0.84
1993 Müller CE, Shi D, Manning M, Daly JW. Synthesis of paraxanthine analogs (1,7-disubstituted xanthines) and other xanthines unsubstituted at the 3-position: structure-activity relationships at adenosine receptors. Journal of Medicinal Chemistry. 36: 3341-9. PMID 8230124  0.84
1993 Nikodijević O, Jacobson KA, Daly JW. Locomotor activity in mice during chronic treatment with caffeine and withdrawal. Pharmacology, Biochemistry, and Behavior. 44: 199-216. PMID 7679219 DOI: 10.1016/0091-3057(93)90299-9  0.84
1993 Daly JW, Garraffo HM, Spande TF. Chapter 3 Amphibian Alkaloids Alkaloids: Chemistry and Pharmacology. 43: 185-288. DOI: 10.1016/S0099-9598(08)60136-4  0.84
1993 Nikodijevic O, Jacobson KA, Daly JW. Effects of combinations of methylxanthines and adenosine analogs on locomotor activity in control and chronic caffeine-treated mice Drug Development Research. 30: 104-110. DOI: 10.1002/ddr.430300209  0.68
1993 Nikodijevic O, Jacobson KA, Daly JW. Acute treatment of mice with high doses of caffeine: An animal model for choreiform movement Drug Development Research. 30: 121-128.  0.84
1992 Holbrook PG, Pannell LK, Murata Y, Daly JW. Bis(monoacylglycero)phosphate from PC12 cells, a phospholipid that can comigrate with phosphatidic acid: molecular species analysis by fast atom bombardment mass spectrometry. Biochimica Et Biophysica Acta. 1125: 330-4. PMID 1596522 DOI: 10.1016/0005-2760(92)90063-2  0.6
1992 Daly JW, Padgett WL. Agonist activity of 2- and 5'-substituted adenosine analogs and their N6-cycloalkyl derivatives at A1- and A2-adenosine receptors coupled to adenylate cyclase. Biochemical Pharmacology. 43: 1089-93. PMID 1554381 DOI: 10.1016/0006-2952(92)90616-Q  0.6
1992 Daly JW, Secunda SI, Garraffo HM, Spande TF, Wisnieski A, Nishihira C, Cover JF. Variability in alkaloid profiles in neotropical poison frogs (Dendrobatidae): genetic versus environmental determinants. Toxicon : Official Journal of the International Society On Toxinology. 30: 887-98. PMID 1523680 DOI: 10.1016/0041-0101(92)90387-K  0.72
1992 Spande TF, Garraffo HM, Yeh HJ, Pu QL, Pannell LK, Daly JW. A new class of alkaloids from a dendrobatid poison frog: a structure for alkaloid 251F. Journal of Natural Products. 55: 707-22. PMID 1522417  0.72
1992 Holbrook PG, Pannell LK, Murata Y, Daly JW. Molecular species analysis of a product of phospholipase D activation. Phosphatidylethanol is formed from phosphatidylcholine in phorbol ester- and bradykinin-stimulated PC12 cells. The Journal of Biological Chemistry. 267: 16834-40. PMID 1512226  0.32
1992 Dumbacher JP, Beehler BM, Spande TF, Garraffo HM, Daly JW. Homobatrachotoxin in the genus Pitohui: chemical defense in birds? Science (New York, N.Y.). 258: 799-801. PMID 1439786  0.84
1992 Daly JW, Caceres J, Moni RW, Gusovsky F, Moos M, Seamon KB, Milton K, Myers CW. Frog secretions and hunting magic in the upper Amazon: identification of a peptide that interacts with an adenosine receptor. Proceedings of the National Academy of Sciences of the United States of America. 89: 10960-3. PMID 1438301  0.32
1992 Jacobson KA, Nikodijevic O, Ji XD, Berkich DA, Eveleth D, Dean RL, Hiramatsu KI, Kassell NF, Van Galen PJM, Lee KS, Bartus RT, Daly JW, LaNoue KF, Maillard M. Synthesis and biological activity of N6-(p-sulfophenyl)alkyl and N6-sulfoalkyl derivatives of adenosine: Water-soluble and peripherally selective adenosine agonists Journal of Medicinal Chemistry. 35: 4143-4149. PMID 1433217  0.32
1992 Murata M, Sasaki M, Yokoyama A, Iwashita T, Gusovsky F, Daly JW, Yasumoto T. Partial structures and binding studies of maitotoxin, the most potent marine toxin. Bulletin De La SociéTé De Pathologie Exotique (1990). 85: 470-3. PMID 1340347  0.32
1992 Gusovsky F, Padgett WL, Creveling CR, Daly JW. Interaction of pumiliotoxin B with an "alkaloid-binding domain" on the voltage-dependent sodium channel. Molecular Pharmacology. 42: 1104-8. PMID 1336116  0.72
1992 Murata M, Gusovsky F, Yasumoto T, Daly JW. Selective stimulation of Ca2+ flux in cells by maitotoxin. European Journal of Pharmacology. 227: 43-9. PMID 1330638 DOI: 10.1016/0922-4106(92)90140-Q  0.32
1992 Soergel DG, Yasumoto T, Daly JW, Gusovsky F. Maitotoxin effects are blocked by SK&F 96365, an inhibitor of receptor-mediated calcium entry. Molecular Pharmacology. 41: 487-93. PMID 1312215  1
1992 Hide I, Padgett WL, Jacobson KA, Daly JW. A2A adenosine receptors from rat striatum and rat pheochromocytoma PC12 cells: characterization with radioligand binding and by activation of adenylate cyclase. Molecular Pharmacology. 41: 352-9. PMID 1311411  0.6
1992 Choi OH, Padgett WL, Daly JW. Effects of the amphiphilic peptides melittin and mastoparan on calcium influx, phosphoinositide breakdown and arachidonic acid release in rat pheochromocytoma PC12 cells. The Journal of Pharmacology and Experimental Therapeutics. 260: 369-75. PMID 1309880  0.64
1992 Spande TF, Garraffo HM, Edwards MW, Yeh HJC, Pannell L, Daly JW. Epibatidine: A novel (chloropyridyl)azabicycloheptane with potent analgesic activity from an ecuadoran poison frog Journal of the American Chemical Society. 114: 3475-3478.  0.72
1991 Brackett LE, Daly JW. Relaxant effects of adenosine analogs on guinea pig trachea in vitro: xanthine-sensitive and xanthine-insensitive mechanisms. The Journal of Pharmacology and Experimental Therapeutics. 257: 205-13. PMID 2019986  1
1991 Daly JW, Nishizawa Y, Edwards MW, Waters JA, Aronstam RS. Nicotinic receptor-elicited sodium flux in rat pheochromocytoma PC12 cells: effects of agonists, antagonists, and noncompetitive blockers. Neurochemical Research. 16: 489-500. PMID 1922660 DOI: 10.1007/BF00965571  1
1991 Ueeda M, Thompson RD, Padgett WL, Secunda S, Daly JW, Olsson RA. Cardiovascular actions of adenosines, but not adenosine receptors, differ in rat and guinea pig. Life Sciences. 49: 1351-8. PMID 1921650 DOI: 10.1016/0024-3205(91)90199-L  0.84
1991 Nikodijević O, Sarges R, Daly JW, Jacobson KA. Behavioral effects of A1- and A2-selective adenosine agonists and antagonists: evidence for synergism and antagonism. The Journal of Pharmacology and Experimental Therapeutics. 259: 286-94. PMID 1920121  0.84
1991 Thompson RD, Secunda S, Daly JW, Olsson RA. N6,9-disubstituted adenines: potent, selective antagonists at the A1 adenosine receptor. Journal of Medicinal Chemistry. 34: 2877-82. PMID 1895305  1
1991 Holbrook PG, Pannell LK, Daly JW. Phospholipase D-catalyzed hydrolysis of phosphatidylcholine occurs with P-O bond cleavage. Biochimica Et Biophysica Acta. 1084: 155-8. PMID 1854800 DOI: 10.1016/0005-2760(91)90214-3  0.6
1991 Daly JW, Nishizawa Y, Padgett WL, Tokuyama T, Smith AL, Holmes AB, Kibayashi C, Aronstam RS. 5,8-disubstituted indolizidines: a new class of noncompetitive blockers for nicotinic receptor-channels. Neurochemical Research. 16: 1213-8. PMID 1815137  0.64
1991 Daly JW, Nishizawa Y, Padgett WL, Tokuyama T, McCloskey PJ, Waykole L, Schultz AG, Aronstam RS. Decahydroquinoline alkaloids: noncompetitive blockers for nicotinic acetylcholine receptor-channels in pheochromocytoma cells and Torpedo electroplax. Neurochemical Research. 16: 1207-12. PMID 1815136 DOI: 10.1007/BF00966697  0.84
1991 Thompson RD, Secunda S, Daly JW, Olsson RA. Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors. Journal of Medicinal Chemistry. 34: 3388-90. PMID 1766003  0.32
1991 Ali H, Müller CE, Daly JW, Beaven MA. Methylxanthines block antigen-induced responses in RBL-2H3 cells independently of adenosine receptors or cyclic AMP: evidence for inhibition of antigen binding to IgE. The Journal of Pharmacology and Experimental Therapeutics. 258: 954-62. PMID 1716313  0.48
1991 Adejare A, Nie JY, Hebel D, Brackett LE, Choi O, Gusovsky F, Padgett WL, Daly JW, Creveling CR, Kirk KL. Effect of fluorine substitution on the adrenergic properties of 3-(tert-butylamino)-1-(3,4-dihydroxyphenoxy)-2-propanol. Journal of Medicinal Chemistry. 34: 1063-8. PMID 1672155  0.84
1991 Murata M, Gusovsky F, Sasaki M, Yokoyama A, Yasumoto T, Daly JW. Effect of maitotoxin analogues on calcium influx and phosphoinositide breakdown in cultured cells. Toxicon : Official Journal of the International Society On Toxinology. 29: 1085-96. PMID 1665603 DOI: 10.1016/0041-0101(91)90206-7  0.32
1991 Gusovsky F, Soergel DG, Daly JW. Effects of mastoparan and related peptides on phosphoinositide breakdown in HL-60 cells and cell-free preparations. European Journal of Pharmacology. 206: 309-14. PMID 1655489 DOI: 10.1016/0922-4106(91)90115-X  0.32
1990 Brackett LE, Shamim MT, Daly JW. Activities of caffeine, theophylline, and enprofylline analogs as tracheal relaxants. Biochemical Pharmacology. 39: 1897-904. PMID 2353933 DOI: 10.1016/0006-2952(90)90607-M  0.32
1990 Nikodijević O, Daly JW, Jacobson KA. Characterization of the locomotor depression produced by an A2-selective adenosine agonist. Febs Letters. 261: 67-70. PMID 2307237  0.84
1990 Müller CE, Hide I, Daly JW, Rothenhäusler K, Eger K. 7-Deaza-2-phenyladenines: structure-activity relationships of potent A1 selective adenosine receptor antagonists. Journal of Medicinal Chemistry. 33: 2822-8. PMID 2213835  1
1990 Daly JW, Hide I, Bridson PK. Imidazodiazepinediones: a new class of adenosine receptor antagonists. Journal of Medicinal Chemistry. 33: 2818-21. PMID 2213834  1
1990 Soergel DG, Gusovsky F, Yasumoto T, Daly JW. Stimulatory effects of maitotoxin on insulin release in insulinoma HIT cells: role of calcium uptake and phosphoinositide breakdown. The Journal of Pharmacology and Experimental Therapeutics. 255: 1360-5. PMID 2175805  0.48
1990 Nishizawa Y, Gusovsky F, Daly JW. Local anesthetics: stimulation of incorporation of inositol into phosphoinositides in guinea pig cerebral cortical synaptoneurosomes. Biochimica Et Biophysica Acta. 1054: 213-8. PMID 2169310  0.32
1990 Creveling CR, Bell ME, Burke TR, Chang E, Lewandowski-Lovenberg GA, Kim CH, Rice KC, Daly JW. Procaine isothiocyanate: an irreversible inhibitor of the specific binding of [3H]batrachotoxinin-A benzoate to sodium channels. Neurochemical Research. 15: 441-8. PMID 2167458 DOI: 10.1007/BF00969931  1
1990 Daly JW, Gusovsky F, McNeal ET, Secunda S, Bell M, Creveling CR, Nishizawa Y, Overman LE, Sharp MJ, Rossignol DP. Pumiliotoxin alkaloids: a new class of sodium channel agents. Biochemical Pharmacology. 40: 315-26. PMID 2165404 DOI: 10.1016/0006-2952(90)90694-G  0.64
1990 Schulick A, Gusovsky F, Yasumoto T, Daly JW. Effects of maitotoxin on atrial natriuretic factor-mediated accumulation of cyclic GMP in PC12 cells. Life Sciences. 46: 671-8. PMID 2156121 DOI: 10.1016/0024-3205(90)90071-X  1
1990 Gusovsky F, Bitran JA, Yasumoto T, Daly JW. Mechanism of maitotoxin-stimulated phosphoinositide breakdown in HL-60 cells. The Journal of Pharmacology and Experimental Therapeutics. 252: 466-73. PMID 2156045  0.32
1990 Choi OH, Padgett WL, Nishizawa Y, Gusovsky F, Yasumoto T, Daly JW. Maitotoxin: effects on calcium channels, phosphoinositide breakdown, and arachidonate release in pheochromocytoma PC12 cells. Molecular Pharmacology. 37: 222-30. PMID 2154671  1
1990 Gusovsky F, Daly JW. Maitotoxin: a unique pharmacological tool for research on calcium-dependent mechanisms. Biochemical Pharmacology. 39: 1633-9. PMID 1971510  0.32
1990 Gusovsky F, Nishizawa Y, Padgett W, McNeal ET, Rice K, Kim CH, Creveling CR, Daly JW. Voltage-dependent sodium channels in synaptoneurosomes: studies with 22Na+ influx and [3H]saxitoxin and [3H]batrachotoxinin-A 20-alpha-benzoate binding. Effects of proparacaine isothiocyanate. Brain Research. 518: 101-6. PMID 1697206  0.64
1989 Morgan PF, Deckert J, Jacobson KA, Marangos PJ, Daly JW. Potent convulsant actions of the adenosine receptor antagonist, xanthine amine congener (XAC). Life Sciences. 45: 719-28. PMID 2779359 DOI: 10.1016/0024-3205(89)90091-X  0.84
1989 Jacobson KA, Kiriasis L, Barone S, Bradbury BJ, Kammula U, Campagne JM, Secunda S, Daly JW, Neumeyer JL, Pfleiderer W. Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors. Journal of Medicinal Chemistry. 32: 1873-9. PMID 2754711  1
1989 Shamim MT, Ukena D, Padgett WL, Daly JW. Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions. Journal of Medicinal Chemistry. 32: 1231-7. PMID 2724296  1
1989 Gusovsky F, Secunda SI, Daly JW. Pyrethroids: involvement of sodium channels in effects on inositol phosphate formation in guinea pig synaptoneurosomes. Brain Research. 492: 72-8. PMID 2546657  0.32
1989 Gusovsky F, Yasumoto T, Daly JW. Calcium-dependent effects of maitotoxin on phosphoinositide breakdown and on cyclic AMP accumulation in PC12 and NCB-20 cells. Molecular Pharmacology. 36: 44-53. PMID 2546052  0.32
1989 Gusovsky F, Yasumoto T, Daly JW. Maitotoxin, a potent, general activator of phosphoinositide breakdown. Febs Letters. 243: 307-12. PMID 2537233  0.32
1988 Deckert J, Morgan PF, Bisserbe JC, Jacobson KA, Kirk KL, Daly JW, Marangos PJ. Autoradiographic localization of mouse brain adenosine receptors with an antagonist ([3H]xanthine amine congener) ligand probe. Neuroscience Letters. 86: 121-6. PMID 3368115 DOI: 10.1016/0304-3940(88)90557-5  0.84
1988 Shamim MT, Ukena D, Padgett WL, Hong O, Daly JW. 8-Aryl-and 8-cycloalkyl-1,3-dipropylxanthines: further potent and selective antagonists for A1-adenosine receptors. Journal of Medicinal Chemistry. 31: 613-7. PMID 3346878  0.32
1988 Edwards MW, Daly JW, Myers CW. Alkaloids from a panamanian poison frog, Dendrobates speciosus: identification of pumiliotoxin-A and allopumiliotoxin class alkaloids, 3,5-disubstituted indolizidines, 5-substituted 8-methylindolizidines, and a 2-methyl-6-nonyl-4-hydroxypiperidine. Journal of Natural Products. 51: 1188-97. PMID 3236011  0.72
1988 Seale TW, Abla KA, Shamim MT, Carney JM, Daly JW. 3,7-Dimethyl-1-propargylxanthine: a potent and selective in vivo antagonist of adenosine analogs. Life Sciences. 43: 1671-84. PMID 3193854 DOI: 10.1016/0024-3205(88)90478-X  0.6
1988 Daly JW, Padgett WL, Eger K. 7-Deaza-9-phenyladenines. A new class of adenosine receptor antagonists. Biochemical Pharmacology. 37: 3749-53. PMID 3178888  0.64
1988 Jacobson KA, de la Cruz R, Schulick R, Kiriasis L, Padgett W, Pfleiderer W, Kirk KL, Neumeyer JL, Daly JW. 8-Substituted xanthines as antagonists at A1- and A2-adenosine receptors. Biochemical Pharmacology. 37: 3653-61. PMID 3178879 DOI: 10.1016/0006-2952(88)90398-X  0.84
1988 Peet NP, Dickerson GA, Abdallah AH, Daly JW, Ukena D. Benzo[1,2-c:5,4-c']dipyrazoles: non-xanthine adenosine antagonists. Journal of Medicinal Chemistry. 31: 2034-9. PMID 3172141  0.56
1988 Nishizawa Y, Gusovsky F, Daly JW. Local anesthetics: comparison of effects on batrachotoxin-elicited sodium flux and phosphoinositide breakdown in guinea pig cerebral cortical synaptoneurosomes. Molecular Pharmacology. 34: 707-13. PMID 2848189  0.32
1988 Adejare A, Gusovsky F, Padgett W, Creveling CR, Daly JW, Kirk KL. Syntheses and adrenergic activities of ring-fluorinated epinephrines. Journal of Medicinal Chemistry. 31: 1972-7. PMID 2845082  0.72
1988 Gusovsky F, Daly JW, Yasumoto T, Rojas E. Differential effects of maitotoxin on ATP secretion and on phosphoinositide breakdown in rat pheochromocytoma cells. Febs Letters. 233: 139-42. PMID 2838322  0.32
1988 Daly JW, Hong O, Padgett WL, Shamim MT, Jacobson KA, Ukena D. Non-xanthine heterocycles: activity as antagonists of A1- and A2-adenosine receptors. Biochemical Pharmacology. 37: 655-64. PMID 2829919 DOI: 10.1016/0006-2952(88)90139-6  0.6
1988 Albuquerque EX, Daly JW, Warnick JE. Macromolecular sites for specific neurotoxins and drugs on chemosensitive synapses and electrical excitation in biological membranes. Ion Channels. 1: 95-162. PMID 2485004  0.72
1988 Gusovsky F, Daly JW. Formation of second messengers in response to activation of ion channels in excitable cells. Cellular and Molecular Neurobiology. 8: 157-69. PMID 2457443  0.32
1988 Choi OH, Shamim MT, Padgett WL, Daly JW. Caffeine and theophylline analogues: correlation of behavioral effects with activity as adenosine receptor antagonists and as phosphodiesterase inhibitors. Life Sciences. 43: 387-98. PMID 2456442 DOI: 10.1016/0024-3205(88)90517-6  1
1988 Aronstam RS, Edwards MW, Daly JW, Albuquerque EX. Interactions of piperidine derivatives with the nicotinic cholinergic receptor complex from Torpedo electric organ. Neurochemical Research. 13: 171-6. PMID 2452357  0.72
1988 Gusovsky F, Daly JW. Formation of inositol phosphates in synaptoneurosomes of guinea pig brain: stimulatory effects of receptor agonists, sodium channel agents and sodium and calcium ionophores. Neuropharmacology. 27: 95-105. PMID 2451187  0.32
1988 Gusovsky F, Rossignol DP, McNeal ET, Daly JW. Pumiliotoxin B binds to a site on the voltage-dependent sodium channel that is allosterically coupled to other binding sites. Proceedings of the National Academy of Sciences of the United States of America. 85: 1272-6. PMID 2448797  0.32
1988 Daly JW, McNeal E, Gusovsky F, Ito F, Overman LE. Pumiliotoxin alkaloids: relationship of cardiotonic activity to sodium channel activity and phosphatidylinositol turnover. Journal of Medicinal Chemistry. 31: 477-80. PMID 2448459  0.32
1987 Jacobson KA, Ukena D, Padgett W, Daly JW, Kirk KL. Xanthine functionalized congeners as potent ligands at A2-adenosine receptors. Journal of Medicinal Chemistry. 30: 211-4. PMID 3806597  0.84
1987 Jacobson KA, Zimmet J, Schulick R, Barone S, Daly JW, Kirk KL. Adenosine analogs with covalently attached lipids have enhanced potency at A1-adenosine receptors. Febs Letters. 225: 97-102. PMID 3691809  0.84
1987 Evoniuk G, Jacobson KA, Shamim MT, Daly JW, Wurtman RJ. A1- and A2-selective adenosine antagonists: in vivo characterization of cardiovascular effects. The Journal of Pharmacology and Experimental Therapeutics. 242: 882-7. PMID 3656117  0.6
1987 Daly JW, McNeal ET, Gusovsky F. Cardiotonic activities of pumiliotoxin B, pyrethroids and a phorbol ester and their relationships with phosphatidylinositol turnover. Biochimica Et Biophysica Acta. 930: 470-4. PMID 3651511  0.32
1987 Daly JW, Jacobson KA, Ukena D. Adenosine receptors: development of selective agonists and antagonists. Progress in Clinical and Biological Research. 230: 41-63. PMID 3588607  0.84
1987 Ukena D, Padgett WL, Hong O, Daly JW, Daly DT, Olsson RA. N6-substituted 9-methyladenines: a new class of adenosine receptor antagonists. Febs Letters. 215: 203-8. PMID 3582647 DOI: 10.1016/0014-5793(87)80146-1  1
1987 Ukena D, Olsson RA, Daly JW. Definition of subclasses of adenosine receptors associated with adenylate cyclase: interaction of adenosine analogs with inhibitory A1 receptors and stimulatory A2 receptors. Canadian Journal of Physiology and Pharmacology. 65: 365-76. PMID 3580959  0.32
1987 Rao KS, Warnick JE, Daly JW, Albuquerque EX. Pharmacology of the alkaloid pumiliotoxin-B. II. Possible involvement of calcium and sodium-dependent processes in nerve and skeletal muscle. The Journal of Pharmacology and Experimental Therapeutics. 243: 775-83. PMID 3500302  0.48
1987 Daly JW, Myers CW, Whittaker N. Further classification of skin alkaloids from neotropical poison frogs (Dendrobatidae), with a general survey of toxic/noxious substances in the amphibia. Toxicon : Official Journal of the International Society On Toxinology. 25: 1023-95. PMID 3321567 DOI: 10.1016/0041-0101(87)90265-0  0.72
1987 Hollingsworth EB, Daly JW. Inhibition of receptor-mediated stimulation of cyclic AMP accumulation in neuroblastoma-hybrid NCB-20 cells by a phorbol ester. Biochimica Et Biophysica Acta. 930: 272-8. PMID 3040124 DOI: 10.1016/0167-4889(87)90040-1  1
1987 Gusovsky F, McNeal ET, Olubajo O, Kirk KL, Creveling CR, Daly JW. Effects of ring fluorination on the adrenergic properties of phenylephrine. European Journal of Pharmacology. 136: 317-24. PMID 3038567  0.64
1987 Jacobson KA, Ukena D, Padgett W, Kirk KL, Daly JW. Molecular probes for extracellular adenosine receptors. Biochemical Pharmacology. 36: 1697-707. PMID 3036153  0.84
1987 Bolger GT, Marcus KA, Daly JW, Skolnick P. Local anesthetics differentiate dihydropyridine calcium antagonist binding sites in rat brain and cardiac membranes. The Journal of Pharmacology and Experimental Therapeutics. 240: 922-30. PMID 3031279  1
1987 Gusovsky F, Yasumoto T, Daly JW. Maitotoxin stimulates phosphoinositide breakdown in neuroblastoma hybrid NCB-20 cells. Cellular and Molecular Neurobiology. 7: 317-22. PMID 2449966  0.32
1987 Gusovsky F, McNeal ET, Daly JW. Stimulation of phosphoinositide breakdown in brain synaptoneurosomes by agents that activate sodium influx: antagonism by tetrodotoxin, saxitoxin, and cadmium. Molecular Pharmacology. 32: 479-87. PMID 2444871  0.32
1987 Jacobson KA, Lipkowski AW, Moody TW, Padgett W, Pijl E, Kirk KL, Daly JW. Binary drugs: conjugates of purines and a peptide that bind to both adenosine and substance P receptors. Journal of Medicinal Chemistry. 30: 1529-32. PMID 2441057  0.84
1987 Fredholm BB, Jacobson KA, Jonzon B, Kirk KL, Li YO, Daly JW. Evidence that a novel 8-phenyl-substituted xanthine derivative is a cardioselective adenosine receptor antagonist in vivo. Journal of Cardiovascular Pharmacology. 9: 396-400. PMID 2438501 DOI: 10.1097/00005344-198704000-00003  0.84
1986 Daly JW, Padgett WL, Shamim MT. Analogues of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors. Journal of Medicinal Chemistry. 29: 1305-8. PMID 3806581  0.6
1986 Ukena D, Jacobson KA, Padgett WL, Ayala C, Shamim MT, Kirk KL, Olsson RO, Daly JW. Species differences in structure-activity relationships of adenosine agonists and xanthine antagonists at brain A1 adenosine receptors. Febs Letters. 209: 122-8. PMID 3803571 DOI: 10.1016/0014-5793(86)81096-1  1
1986 Daly JW, Spande TF, Whittaker N, Highet RJ, Feigl D, Nishimori N, Tokuyama T, Myers CW. Alkaloids from dendrobatid frogs: structures of two omega-hydroxy congeners of 3-butyl-5-propylindolizidine and occurrence of 2,5-disubstituted pyrrolidines and a 2,6-disubstituted piperidine. Journal of Natural Products. 49: 265-80. PMID 3734811  0.72
1986 Kirk KL, Olubajo O, Buchhold K, Lewandowski GA, Gusovsky F, McCulloh D, Daly JW, Creveling CR. Synthesis and adrenergic activity of ring-fluorinated phenylephrines. Journal of Medicinal Chemistry. 29: 1982-8. PMID 3020250  0.84
1986 Olsson RA, Kusachi S, Thompson RD, Ukena D, Padgett W, Daly JW. N6-substituted N-alkyladenosine-5'-uronamides: bifunctional ligands having recognition groups for A1 and A2 adenosine receptors. Journal of Medicinal Chemistry. 29: 1683-9. PMID 3018244  0.32
1986 Daly JW, Padgett W, Thompson RD, Kusachi S, Bugni WJ, Olsson RA. Structure-activity relationships for N6-substituted adenosines at a brain A1-adenosine receptor with a comparison to an A2-adenosine receptor regulating coronary blood flow. Biochemical Pharmacology. 35: 2467-81. PMID 3017353 DOI: 10.1016/0006-2952(86)90042-0  0.6
1986 Ukena D, Shamim MT, Padgett W, Daly JW. Analogs of caffeine: antagonists with selectivity for A2 adenosine receptors. Life Sciences. 39: 743-50. PMID 3016449 DOI: 10.1016/0024-3205(86)90023-8  0.6
1986 Daly JW, Padgett WL, Shamim MT. Analogues of 1,3-dipropyl-8-phenylxanthine: enhancement of selectivity at A1-adenosine receptors by aryl substituents. Journal of Medicinal Chemistry. 29: 1520-4. PMID 3016270  1
1986 Waters JA, Hollingsworth EB, Daly JW, Lewandowski G, Creveling CR. Anticonvulsant activity of piperidinol and (dialkylamino)alkanol esters. Journal of Medicinal Chemistry. 29: 1512-6. PMID 3016269  0.32
1986 Paul SM, Schwartz RD, Creveling CR, Hollingsworth EB, Daly JW, Skolnick P. GABA receptor-mediated chloride transport in a "cell-free" membrane preparation from brain. Science (New York, N.Y.). 233: 228-9. PMID 3014649 DOI: 10.1126/science.3014649  0.32
1986 Jacobson KA, Yamada N, Kirk KL, Daly JW, Olsson RA. N6-functionalized congeners of adenosine with high potency at A2-adenosine receptors: potential ligands for affinity chromatography. Biochemical and Biophysical Research Communications. 136: 1097-102. PMID 3013167 DOI: 10.1016/0006-291X(86)90446-8  1
1986 Jacobson KA, Ukena D, Kirk KL, Daly JW. [3H]xanthine amine congener of 1,3-dipropyl-8-phenylxanthine: an antagonist radioligand for adenosine receptors. Proceedings of the National Academy of Sciences of the United States of America. 83: 4089-93. PMID 3012550  0.84
1986 Ukena D, Jacobson KA, Kirk KL, Daly JW. A [3H]amine congener of 1,3-dipropyl-8-phenylxanthine. A new radioligand for A2 adenosine receptors of human platelets. Febs Letters. 199: 269-74. PMID 3009222  0.84
1986 Jacobson KA, Kirk KL, Padgett WL, Daly JW. A functionalized congener approach to adenosine receptor antagonists: amino acid conjugates of 1,3-dipropylxanthine. Molecular Pharmacology. 29: 126-33. PMID 3005825  0.84
1986 Ukena D, Daly JW, Kirk KL, Jacobson KA. Functionalized congeners of 1,3-dipropyl-8-phenylxanthine: potent antagonists for adenosine receptors that modulate membrane adenylate cyclase in pheochromocytoma cells, platelets and fat cells. Life Sciences. 38: 797-807. PMID 3005794 DOI: 10.1016/0024-3205(86)90596-5  1
1986 Hollingsworth EB, Ukena D, Daly JW. The protein kinase C activator phorbol-12-myristate-13-acetate enhances cyclic AMP accumulation in pheochromocytoma cells. Febs Letters. 196: 131-4. PMID 3002860 DOI: 10.1016/0014-5793(86)80227-7  1
1986 Sokolove PM, Albuquerque EX, Kauffman FC, Spande TF, Daly JW. Phenolic antioxidants: potent inhibitors of the (Ca2+ + Mg2+)-ATPase of sarcoplasmic reticulum. Febs Letters. 203: 121-6. PMID 2942419 DOI: 10.1016/0014-5793(86)80726-8  0.84
1986 Aronstam RS, Daly JW, Spande TF, Narayanan TK, Albuquerque EX. Interaction of gephyrotoxin and indolizidine alkaloids with the nicotinic acetylcholine receptor-ion channel complex of Torpedo electroplax. Neurochemical Research. 11: 1227-40. PMID 2431336 DOI: 10.1007/BF00965950  0.72
1986 Hollingsworth EB, Sears EB, de la Cruz RA, Gusovsky F, Daly JW. Accumulations of cyclic AMP and inositol phosphates in guinea pig cerebral cortical synaptoneurosomes: enhancement by agents acting at sodium channels. Biochimica Et Biophysica Acta. 883: 15-25. PMID 2425852  0.32
1986 Gusovsky F, Hollingsworth EB, Daly JW. Regulation of phosphatidylinositol turnover in brain synaptoneurosomes: stimulatory effects of agents that enhance influx of sodium ions. Proceedings of the National Academy of Sciences of the United States of America. 83: 3003-7. PMID 2422664  0.32
1986 Albuquerque EX, Deshpande SS, Aracava Y, Alkondon M, Daly JW. A possible involvement of cyclic AMP in the expression of desensitization of the nicotinic acetylcholine receptor. A study with forskolin and its analogs. Febs Letters. 199: 113-20. PMID 2420646 DOI: 10.1016/0014-5793(86)81235-2  1
1986 Gusovsky F, Daly JW. Scorpion venom (Leiurus quinquestriatus) elicits accumulations of inositol phosphates and cyclic AMP in guinea pig cortical synaptoneurosomes. Febs Letters. 199: 107-12. PMID 2420645  0.32
1986 Jacobson KA, Ukena D, Daly JW, Kirk KL. Synthesis of tritiated functionalized congeners of 1,3-dipropylxanthine having high affinity at adenosine receptors Journal of Labelled Compounds and Radiopharmaceuticals. 23: 519-526.  1
1985 Seamon KB, Vaillancourt R, Daly JW. Modulation of forskolin binding to rat brain membranes. Journal of Cyclic Nucleotide and Protein Phosphorylation Research. 10: 535-49. PMID 4086675  0.6
1985 Jakobson KA, Kirk KL, Daly JW, Jonzon B, Li YO, Fredholm BB. A novel 8-phenyl-substituted xanthine derivative is a selective antagonist at adenosine A1-receptors in vivo. Acta Physiologica Scandinavica. 125: 341-2. PMID 3000136 DOI: 10.1111/j.1748-1716.1985.tb07725.x  1
1985 Jacobson KA, Kirk KL, Padgett WL, Daly JW. Functionalized congeners of adenosine: preparation of analogues with high affinity for A1-adenosine receptors. Journal of Medicinal Chemistry. 28: 1341-6. PMID 2993623  1
1985 Jacobson KA, Kirk KL, Padgett WL, Daly JW. Functionalized congeners of 1,3-dialkylxanthines: preparation of analogues with high affinity for adenosine receptors. Journal of Medicinal Chemistry. 28: 1334-40. PMID 2993622  1
1985 Hollingsworth EB, McNeal ET, Burton JL, Williams RJ, Daly JW, Creveling CR. Biochemical characterization of a filtered synaptoneurosome preparation from guinea pig cerebral cortex: cyclic adenosine 3':5'-monophosphate-generating systems, receptors, and enzymes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 5: 2240-53. PMID 2991484  1
1985 Siegl AM, Daly JW. Receptor (norepinephrine), P-site (2',5'-dideoxyadenosine), and calcium-mediated inhibition of prostaglandin and forskolin-activated cyclic AMP-generating systems in human platelets. Journal of Cyclic Nucleotide and Protein Phosphorylation Research. 10: 229-45. PMID 2991349  1
1985 Daly JW. Adenosine receptors. Advances in Cyclic Nucleotide and Protein Phosphorylation Research. 19: 29-46. PMID 2988302  0.48
1985 Hollingsworth EB, Sears EB, Daly JW. An activator of protein kinase C (phorbol-12-myristate-13-acetate) augments 2-chloroadenosine-elicited accumulation of cyclic AMP in guinea pig cerebral cortical particulate preparations. Febs Letters. 184: 339-42. PMID 2987034 DOI: 10.1016/0014-5793(85)80634-7  1
1985 Jacobson KA, Kirk KL, Padgett W, Daly JW. Probing the adenosine receptor with adenosine and xanthine biotin conjugates. Febs Letters. 184: 30-5. PMID 2985445 DOI: 10.1016/0014-5793(85)80646-3  1
1985 Daly JW, Padgett W, Shamim MT, Butts-Lamb P, Waters J. 1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors. Journal of Medicinal Chemistry. 28: 487-92. PMID 2984420  1
1985 Creveling CR, McNeal ET, Lewandowski GA, Rafferty M, Harrison EH, Jacobson AE, Rice KC, Daly JW. Local anesthetic properties of opioids and phencyclidines: interaction with the voltage-dependent, batrachotoxin binding site in sodium channels. Neuropeptides. 5: 253-6. PMID 2582303 DOI: 10.1016/0143-4179(85)90026-5  1
1985 McNeal ET, Lewandowski GA, Daly JW, Creveling CR. [3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of Medicinal Chemistry. 28: 381-8. PMID 2579237  1
1985 Shaw KP, Aracava Y, Akaike A, Daly JW, Rickett DL, Albuquerque EX. The reversible cholinesterase inhibitor physostigmine has channel-blocking and agonist effects on the acetylcholine receptor-ion channel complex. Molecular Pharmacology. 28: 527-38. PMID 2417099  1
1985 Aronstam RS, King CT, Albuquerque EX, Daly JW, Feigl DM. Binding of [3H]perhydrohistrionicotoxin and [3H]phencyclidine to the nicotinic receptor-ion channel complex of Torpedo electroplax. Inhibition by histrionicotoxins and derivatives. Biochemical Pharmacology. 34: 3037-47. PMID 2412560 DOI: 10.1016/0006-2952(85)90145-5  0.72
1985 Hollingsworth EB, Daly JW. Stimulatory effects of biogenic amines and carbamylcholine on 2-chloroadenosine-elicited accumulations of cyclic AMP and on cortical slices Federation Proceedings. 44: No. 563.  1
1984 Daly JW, Highet RJ, Myers CW. Occurrence of skin alkaloids in non-dendrobatid frogs from Brazil (Bufonidae), Australia (Myobatrachidae) and Madagascar (Mantellinae). Toxicon : Official Journal of the International Society On Toxinology. 22: 905-19. PMID 6523513 DOI: 10.1016/0041-0101(84)90182-X  0.72
1984 Seamon KB, Vaillancourt R, Edwards M, Daly JW. Binding of [3H]forskolin to rat brain membranes. Proceedings of the National Academy of Sciences of the United States of America. 81: 5081-5. PMID 6433343  1
1984 Daly JW. Forskolin, adenylate cyclase, and cell physiology: an overview. Advances in Cyclic Nucleotide and Protein Phosphorylation Research. 17: 81-9. PMID 6328947  1
1984 Souccar C, Varanda WA, Aronstam RS, Daly JW, Albuquerque EX. Interactions of gephyrotoxin with the acetylcholine receptor-ionic channel complex. II. Enhancement of desensitization. Molecular Pharmacology. 25: 395-400. PMID 6328265  1
1984 Souccar C, Varanda WA, Daly JW, Albuquerque EX. Interactions of gephyrotoxin with the acetylcholine receptor-ionic channel complex. I. Blockade of the ionic channel. Molecular Pharmacology. 25: 384-94. PMID 6328264  0.48
1984 Sugio K, Daly JW. Effects of forskolin analogs, phosphodiesterase inhibitors and 8-bromo cyclic AMP on plasma exudations induced with bradykinin and prostaglandin E1 in rat skin. Life Sciences. 34: 123-32. PMID 6319936 DOI: 10.1016/0024-3205(84)90582-4  1
1984 Aracava Y, Ikeda SR, Daly JW, Brookes N, Albuquerque EX. Interactions of bupivacaine with ionic channels of the nicotinic receptor. Analysis of single-channel currents. Molecular Pharmacology. 26: 304-13. PMID 6090885  0.84
1984 Ikeda SR, Aronstam RS, Daly JW, Aracava Y, Albuquerque EX. Interactions of bupivacaine with ionic channels of the nicotinic receptor. Electrophysiological and biochemical studies. Molecular Pharmacology. 26: 293-303. PMID 6090884  1
1984 Sugio K, Daly JW. Adenosine analogs: potentiation of bradykinin-induced plasma exudation in rat skin and prevention by caffeine and theophylline. Life Sciences. 35: 1575-83. PMID 6090841 DOI: 10.1016/0024-3205(84)90356-4  1
1984 Glennon RA, Tejani-Butt SM, Padgett W, Daly JW. Mesoionic xanthine analogues: antagonists of adenosine receptors. Journal of Medicinal Chemistry. 27: 1364-7. PMID 6090665  0.32
1984 Weir RL, Padgett W, Daly JW, Anderson SM. Interaction of anticonvulsant drugs with adenosine receptors in the central nervous system. Epilepsia. 25: 492-8. PMID 6086302  0.56
1984 Hollingsworth EB, Creveling CR, McNeal ET, Daly JW. A filtered neurosome enriched preparation from brain: Morphology, receptors, enzymes and cyclic AMP-responses Federation Proceedings. 43: no. 4728.  1
1984 Sugio K, Daly JW. Adenosine-induced plasma exudation in rat skin: Inhibition by methylxanthines forskolin, isoproterenol, prostaglandin E1, 8- bromocyclic AMP and phosphodiesterase inhibitors Federation Proceedings. 43: no. 593.  1
1983 Myers CW, Daly JW. Dart-poison frogs. Scientific American. 248: 120-33. PMID 6836257  0.72
1983 Seamon KB, Daly JW, Metzger H, de Souza NJ, Reden J. Structure-activity relationships for activation of adenylate cyclase by the diterpene forskolin and its derivatives. Journal of Medicinal Chemistry. 26: 436-9. PMID 6681845 DOI: 10.1021/jm00357a021  1
1983 Daly JW, Butts-Lamb P, Padgett W. Subclasses of adenosine receptors in the central nervous system: interaction with caffeine and related methylxanthines. Cellular and Molecular Neurobiology. 3: 69-80. PMID 6309393 DOI: 10.1007/BF00734999  1
1983 Karnushina I, Suzuki R, Padgett W, Daly JW. Degeneration of CA1 neurons in hippocampus after ischemia in Mongolian gerbils: cyclic AMP-systems. Brain Research. 268: 87-94. PMID 6305459  0.56
1983 Bruns RF, Daly JW, Snyder SH. Adenosine receptor binding: structure-activity analysis generates extremely potent xanthine antagonists. Proceedings of the National Academy of Sciences of the United States of America. 80: 2077-80. PMID 6300892 DOI: 10.1073/PNAS.80.7.2077  0.6
1983 Creveling CR, McNeal ET, Daly JW, Brown GB. Batrachotoxin-induced depolarization and [3H]batrachotoxinin-a 20 alpha-benzoate binding in a vesicular preparation from guinea pig cerebral cortex. Molecular Pharmacology. 23: 350-8. PMID 6300644  0.64
1983 Bruns RF, Katims JJ, Annau Z, Snyder SH, Daly JW. Adenosine receptor interactions and anxiolytics. Neuropharmacology. 22: 1523-9. PMID 6199685 DOI: 10.1016/0028-3908(83)90121-1  0.6
1983 Seamon KB, Daly JW. Forskolin, cyclic AMP and cellular physiology Trends in Pharmacological Sciences. 4: 120-123. DOI: 10.1016/0165-6147(83)90326-7  1
1982 Ebstein RP, Daly JW. Release of norepinephrine and dopamine from brain vesicular preparations: effects of calcium antagonists. Cellular and Molecular Neurobiology. 2: 205-13. PMID 7159902 DOI: 10.1007/BF00711148  1
1982 Ebstein RP, Daly JW. Release of norepinephrine and dopamine from brain vesicular preparations: effects of adenosine analogues. Cellular and Molecular Neurobiology. 2: 193-204. PMID 7159901 DOI: 10.1007/BF00711147  1
1982 Seamon KB, Daly JW. Calmodulin stimulation of adenylate cyclase in rat brain membranes does not require GTP. Life Sciences. 30: 1457-64. PMID 7087674 DOI: 10.1016/0024-3205(82)90559-8  1
1982 Nimit Y, Law J, Daly JW. Binding of 2',5'-dideoxyadenosine to brain membranes. Comparison to P-site inhibition of adenylate cyclase. Biochemical Pharmacology. 31: 3279-87. PMID 6983353  0.64
1982 Ebstein RP, Seamon K, Creveling CR, Daly JW. Release of norepinephrine from brain vesicular preparations: effects of an adenylate cyclase activator, forskolin, and a phosphodiesterase inhibitor. Cellular and Molecular Neurobiology. 2: 179-92. PMID 6891616  0.64
1982 Seamon KB, Daly JW. Guanosine 5'-(beta, gamma-imido)triphosphate inhibition of forskolin-activated adenylate cyclase is mediated by the putative inhibitory guanine nucleotide regulatory protein. The Journal of Biological Chemistry. 257: 11591-6. PMID 6288693  1
1982 Siegl AM, Daly JW, Smith JB. Inhibition of aggregation and stimulation of cyclic AMP generation in intact human platelets by the diterpene forskolin. Molecular Pharmacology. 21: 680-7. PMID 6287202  1
1982 Spivak CE, Maleque MA, Oliveira AC, Masukawa LM, Tokuyama T, Daly JW, Albuquerque EX. Actions of the histrionicotoxins at the ion channel of the nicotinic acetylcholine receptor and at the voltage-sensitive ion channels of muscle membranes. Molecular Pharmacology. 21: 351-61. PMID 6285171  1
1982 Daly JW. Adenosine receptors: targets for future drugs. Journal of Medicinal Chemistry. 25: 197-207. PMID 6279840  1
1982 Warnick JE, Jessup PJ, Overman LE, Eldefrawi ME, Nimit Y, Daly JW, Albuquerque EX. Pumiliotoxin-C and synthetic analogues. A new class of nicotinic antagonists. Molecular Pharmacology. 22: 565-73. PMID 6130469  1
1982 Daly JW, Padgett W, Seamon KB. Activation of cyclic AMP-generating systems in brain membranes and slices by the diterpene forskolin: augmentation of receptor-mediated responses. Journal of Neurochemistry. 38: 532-44. PMID 6125572  0.56
1982 Daly JW. Biologically active alkaloids from poison frogs (dendrobatidae) Toxin Reviews. 1: 33-86. DOI: 10.3109/15569548209016467  1
1982 Kaufmann FC, Albuquerque EX, Daly JW. Inhibition of Ca++-dependent ATPase by pumiliotoxin B and 251-D Federation Proceedings. 41: No. 6996.  1
1982 Souccar C, Maleque MA, Daly JW, Albuquerque EX. Actions of gephyrotoxin (GTX) on the ionic channel of the nicotinic receptor and on membrane excitability Federation Proceedings. 41: 6012.  1
1982 Seamon KB, Daly JW. Forskolin-activated adenylate cyclase can be inhibited by GppNHp Federation Proceedings. 41: No. 7019.  1
1981 Tamburini R, Albuquerque EX, Daly JW, Kauffman FC. Inhibition of calcium-dependent ATPase from sarcoplasmic reticulum by a new class of indolizidine alkaloids, pumiliotoxins A, B, and 251D. Journal of Neurochemistry. 37: 775-80. PMID 6456330  0.72
1981 Albuquerque EX, Warnick JE, Maleque MA, Kauffman FC, Tamburini R, Nimit Y, Daly JW. The pharmacology of pumiliotoxin-B. I. Interaction with calcium sites in the sarcoplasmic reticulum of skeletal muscle. Molecular Pharmacology. 19: 411-24. PMID 6455594  1
1981 Seamon KB, Daly JW. Forskolin: A unique diterpene activator of cyclic AMP-generating systems Journal of Cyclic Nucleotide Research. 7: 201-204. PMID 6278005  1
1981 Aguayo LG, Pazhenchevsky B, Daly JW, Albuquerque EX. The ionic channel of the acetylcholine receptor. Regulation by sites outside and inside the cell membrane which are sensitive to quaternary ligands. Molecular Pharmacology. 20: 345-55. PMID 6272092  0.72
1981 Seamon KB, Padgett W, Daly JW. Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells. Proceedings of the National Academy of Sciences of the United States of America. 78: 3363-7. PMID 6267587  0.56
1981 Snyder SH, Katims JJ, Annau Z, Bruns RF, Daly JW. Adenosine receptors and behavioral actions of methylxanthines [caffeine/theophylline/N 6-cyclohexyladenosine/N 6-(phenylisopropyl)adenosine] Proceedings of the National Academy of Sciences of the United States of America. 78: 3260-3264. PMID 6265942 DOI: 10.1073/pnas.78.5.3260  1
1981 Nimit Y, Skolnick P, Daly JW. Adenosine and cyclic AMP in rat cerebral cortical slices: effects of adenosine uptake inhibitors and adenosine deaminase inhibitors. Journal of Neurochemistry. 36: 908-12. PMID 6259294  1
1981 Daly JW, Bruns RF, Snyder SH. Adenosine receptors in the central nervous system: relationship to the central actions of methylxanthines. Life Sciences. 28: 2083-97. PMID 6114369 DOI: 10.1016/0024-3205(81)90614-7  1
1981 Brown GB, Daly JW. Interaction of batrachotoxinin-A benzoate with voltage-sensitive sodium channels: the effects of pH. Cellular and Molecular Neurobiology. 1: 361-71. PMID 6101082 DOI: 10.1007/BF00716271  1
1981 Daly JW, Padgett WL, Seamon KB. Forskolin: A unique triterpene activator of adenylate cyclase Federation Proceedings. 40: No. 2267.  1
1981 Creveling CR, McNeal ET, Daly JW. Effects of anemone toxin and cocaine on batrachotoxin induced depolarization of a vesicular preparation from guinea pig cerebral cortex Federation Proceedings. 40: 395.  1
1981 Seamon K, Padgett W, Daly JW. Forskolin: a unique diterpene activator of adenylate cyclase which potentiates calcium-calmodulin and hormone responses Federation Proceedings. 40: 1092.  1
1980 Oertel WH, Schmechel DE, Daly JW, Tappaz ML, Kopin IJ. Localization of glutamate decarboxylase on line-immunoelectrophoresis and two-dimensional electrophoresis by use of the radioactive suicide substrate [2-3H]-gamma-acetylenic GABA. Life Sciences. 27: 2133-41. PMID 7207011 DOI: 10.1016/0024-3205(80)90495-6  1
1980 McNeal ET, Creveling CR, Daly JW. Cyclic AMP-generating systems in cell-free preparations from guinea pig cerebral cortex: Loss of adenosine and amine responsiveness due to low levels of endogenous adenosine Journal of Neurochemistry. 35: 338-342. PMID 6256482  1
1980 Daly JW, McNeal E, Partington C, Neuwirth M, Creveling CR. Accumulations of cyclic AMP in adenine-labeled cell-free preparations from guinea pig cerebral cortex: role of alpha-adrenergic and H1-histaminergic receptors. Journal of Neurochemistry. 35: 326-37. PMID 6256481 DOI: 10.1111/j.1471-4159.1980.tb06268.x  1
1980 Partington CR, Edwards MW, Daly JW. Calcium-dependent desensitization of adenylate cyclase in rat cerebral cortical slices Journal of Neurochemistry. 34: 76-82. PMID 6256474  1
1980 Nimit Y, Cantacuzene D, Kirk KL, Creveling CR, Daly JW. The binding of fluorocatecholamines to adrenergic and dopaminergic receptors in rat brain membranes Life Sciences. 27: 1577-1585. PMID 6255279 DOI: 10.1016/0024-3205(80)90567-6  1
1980 Bruns RF, Daly JW, Snyder SH. Adenosine receptors in brain membranes: Binding of N6-cyclohexyl[3H]adenosine and 1,3-diethyl-8-[3H]phenylxanthine Proceedings of the National Academy of Sciences of the United States of America. 77: 5547-5551. PMID 6254090 DOI: 10.1073/pnas.77.9.5547  1
1980 Partington CR, Edwards MW, Daly JW. Regulation of cyclic AMP formation in brain tissue by α-adrenergic receptors: Requisite intermediacy of prostaglandins of the E series Proceedings of the National Academy of Sciences of the United States of America. 77: 3024-3028. PMID 6248884  1
1980 Davis CW, Daly JW. Activation of rat cerebral cortical 3',5'-cyclic nucleotide phosphodiesterase activity by gangliosides Molecular Pharmacology. 17: 206-211. PMID 6248757  1
1980 Brossi A, Rice KC, Mak CP, Reden J, Jacobson AE, Nimitkitpaisan Y, Skolnick P, Daly J. Mammalian alkaloids. 8. Synthesis and biological effects of tetrahydropapaveroline related 1-benzyltetrahydroisoquinolines. Journal of Medicinal Chemistry. 23: 648-52. PMID 6248642  1
1980 Daly JW, Myers CW, Warnick JE, Albuquerque EX. Levels of batrachotoxin and lack of sensitivity to its action in poison-dart frogs (Phyllobates). Science (New York, N.Y.). 208: 1383-5. PMID 6246586  1
1980 Pons F, Bruns RF, Daly JW. Depolarization-evoked accumulation of cyclic AMP in brain slices: The requisite intermediate adenosine is not derived from hydrolysis of released ATP Journal of Neurochemistry. 34: 1319-1323. PMID 6246208 DOI: 10.1111/j.1471-4159.1980.tb09977.x  1
1980 Bruns RF, Pons F, Daly JW. Glutamate- and veratridine-elicited accumulations of cyclic AMP in brain slices: a role for factors which potentiate adenosine-responsive systems Brain Research. 189: 550-555. PMID 6245768 DOI: 10.1016/0006-8993(80)90367-4  1
1980 Creveling CR, McNeal ET, McCulloh DH, Daly JW. Membrane potentials in cell-free preparations from guinea pig cerebral cortex: Effect of depolarizing agents and cyclic nucleotides Journal of Neurochemistry. 35: 922-932. PMID 6109002  1
1980 Daly JW, Padgett W, Nimitkitpaisan Y, Creveling CR, Cantacuzene D, Kirk KL. Fluoronorepinephrines: Specific agonists for the activation of alpha and beta adrenergic-sensitive cyclic AMP-generating systems in brain slices Journal of Pharmacology and Experimental Therapeutics. 212: 382-389. PMID 6102142  1
1980 Flier J, Edwards MW, Daly JW, Myers CW. Widespread occurrence in frogs and toads of skin compounds interacting with the ouabain site of Na+,K+-ATPase Science. 208: 505-508.  1
1980 Bruns RF, Daly JW, Snyder SH. N6-cyclohexyladenosine and 1,3-diethyl-8-phenylxanthine label two distinct adenosine receptors in brain membranes Federation Proceedings. 39: 3909.  1
1979 Neuwirth M, Daly JW, Myers CW, Tice LW. Morphology of the granular secretory glands in skin of poison-dart frogs (Dendrobatidae). Tissue & Cell. 11: 755-71. PMID 524345 DOI: 10.1016/0040-8166(79)90029-6  1
1979 Partington CR, Daly JW. Effect of proteases and protease inhibitors on adenylate cyclase activity in rat cerebral cortical membranes Archives of Biochemistry and Biophysics. 198: 255-262. PMID 507844 DOI: 10.1016/0003-9861(79)90417-X  1
1979 Partington CR, Daly JW. Effect of gangliosides on adenylate cyclase activity in rat cerebral cortical membranes Molecular Pharmacology. 15: 484-491. PMID 492141  1
1979 Smellie FW, Davis CW, Daly JW, Wells JN. Alkylxanthines: Inhibition of adenosine-elicited accumulation of cyclic AMP in brain slices and of brain phosphodiesterase activity Life Sciences. 24: 2475-2481. PMID 225626 DOI: 10.1016/0024-3205(79)90458-2  1
1979 Smellie FW, Daly JW, Wells JN. 1-Isoamyl-3-isobutylxanthine: A remarkably potent agent for the potentiation of norepinephrine, histamine, and adenosine-elicited accumulations of cyclic AMP in brain slices Life Sciences. 25: 1917-1924. PMID 93674 DOI: 10.1016/0024-3205(79)90613-1  1
1979 Daly JW, Padgett W, Nimitkitpaisan Y. Fluoronorepinephrines: Selective α- and β-adrenergic agents for the activation of cyclic AMP-generating systems in rat brain slices Federation Proceedings. 38: No. 1603.  1
1978 Eldefrawi ME, Eldefrawi AT, Mansour NA, Daly JW, Witkop B, Albuquerque EX. Acetylcholine receptor and ionic channel of Torpedo electroplax: binding of perhydrohistrionicotoxin to membrane and solubilized preparations. Biochemistry. 17: 5474-84. PMID 728410  1
1978 Skolnick P, Nimitkitpaisan Y, Stalvey L, Daly JW. Inhibition of brain adenosine deaminase by 2'-deoxycoformycin and erythro-9-(2-hydroxy-3-nonyl) adenine. Journal of Neurochemistry. 30: 1479-82. PMID 670988  1
1978 Garrison DL, Albuquerque EX, Warnick JE, Daly JW, Witkop B. Antagonism of carbamylcholine-induced depolarization by batrachotoxin and veratridine. Molecular Pharmacology. 14: 111-21. PMID 304959  1
1978 Skolnick P, Daly JW, Segal DS. Neurochemical and behavioral effects of clonidine and related imidazolines: interaction with alpha-adrenoceptors. European Journal of Pharmacology. 47: 451-5. PMID 204500 DOI: 10.1016/0014-2999(78)90126-7  1
1978 Davis JN, Arnett CD, Hoyler E, Stalvey LP, Daly JW, Skolnick P. Brain alpha-adrenergic receptors: comparison of [3H]WB 4101 binding with norepinephrine-stimulated cyclic AMP accumulation in rat cerebral cortex. Brain Research. 159: 125-35. PMID 31963  1
1978 Skolnick P, Stalvey LP, Daly JW, Hoyler E, Davis JN. Binding of alpha-and beta-adrenergic ligands to cerebral cortical membranes: effect of 6-hydroxydopamine treatment and relationship to the responsiveness of cyclic amp-generating systems in two rat strains. European Journal of Pharmacology. 47: 201-10. PMID 23299 DOI: 10.1016/0014-2999(78)90391-6  1
1977 Daly JW, Witkop B, Tokuyama T, Nishikawa T, Karle IL. Gephyrotoxins, histrionicotoxins and pumiliotoxins from the neotropical frog Dendrobates histrionicus. Helvetica Chimica Acta. 60: 1128-40. PMID 863724 DOI: 10.1002/hlca.19770600336  1
1977 Eldefrawi AT, Eldefrawi ME, Albuquerque EX, Oliveira AC, Mansour N, Adler M, Daly JW, Brown GB, Burgermeister W, Witkop B. Perhydrohistrionicotoxin: a potential ligand for the ion conductance modulator of the acetylcholine receptor. Proceedings of the National Academy of Sciences of the United States of America. 74: 2172-6. PMID 301278  1
1977 Skolnick P, Daly JW. Strain differences in responsiveness of norepinephrine-sensitive adenosine 3',5'-monophosphate-generating systems in rat brain slices after intraventricular administration of 6-hydroxydopamine. European Journal of Pharmacology. 41: 145-52. PMID 188662  1
1977 Skolnick P, Stalvey LP, Daly JW. Blockade of central beta-adrenergic receptors by tazolol (1-isopropylamino-3-(2-thiazoloxy)-2-propanol). Life Sciences. 21: 1655-63. PMID 23478  1
1976 Skolnick P, Daly JW. Interaction of clonidine with pre- and post-synaptic adrenergic receptors of rat brain: effects on cyclic AMP-generating systems. European Journal of Pharmacology. 39: 11-21. PMID 183964  1
1976 Skolnick P, Daly JW. Antagonism of alpha- and beta-adrenergic-mediated accumulations of cyclic AMP in rat cerebral cortical slices by the beta-antagonist (-)alprenolol. Life Sciences. 19: 497-503. PMID 8683  1
1976 Skolnick P, Daly JW, Freedman R, Hoffer BJ. Interrelationship between catecholamine-stimulated formation of adenosine 3',5'-monophosphate in cerebellar slices and inhibitory effects on cerebellar Purkinje cells: antagonism by neuroleptic compounds. The Journal of Pharmacology and Experimental Therapeutics. 197: 280-92. PMID 5595  1
1975 Skolnick P, Daly JW. Stimulation of adenosine 3',5'-monophosphate formation by alpha and beta adrenergic agonists in rat cerebral cortical slices: effects of clonidine. Molecular Pharmacology. 11: 545-51. PMID 241008  1
1975 Skolnick P, Daly JW. Stimulation of adenosine 3',5'-monophosphate formation in rat cerebral cortical slices by methoxamine: interaction with an alpha adrenergic receptor. The Journal of Pharmacology and Experimental Therapeutics. 193: 549-58. PMID 238025  1
1975 Weissman BA, Daly JW, Skolnick P. Diethylstilbestrol-elicited accumulation of cyclic AMP in incubated rat hypothalamus. Endocrinology. 97: 1559-66. PMID 173528 DOI: 10.1210/endo-97-6-1559  1
1975 Skolnick P, Schultz J, Daly JW. Repetitive stimulation of cyclic adenosine 3',5'-monophosphate formation by adrenergic agonists in incubated slices from rat cerebral cortex. Journal of Neurochemistry. 24: 1263-5. PMID 165265  1
1975 Skolnick P, Daly JW. Functional compartments of adenine nucleotides serving as precursors of adenosine 3',5'-monophosphate in mouse cerebral cortex. Journal of Neurochemistry. 24: 451-6. PMID 163293  1
1974 Tokuyama T, Uenoyama K, Brown G, Daly JW, Witkop B. Allenic and acetylenic spiropiperidine alkaloids from the neotropical frog, Dendrobates histrionicus. Helvetica Chimica Acta. 57: 2597-604. PMID 4443292 DOI: 10.1002/hlca.19740570835  0.64
1974 Skolnick P, Daly JW. The accumulation of adenosine 3',5'-monophosphate in cerebral cortical slices of the quaking mouse, a neurologic mutant. Brain Research. 73: 513-25. PMID 4366158  1
1974 Skolnick P, Daly JW. Norepinephrine-sensitive adenylate cyclases in rat brain: relation to behavior and tyrosine hydroxylase. Science (New York, N.Y.). 184: 175-7. PMID 4150105  1
1972 Lutz WB, Creveling CR, Daly JW, Witkop B. Sulfur analogs of dopamine and norepinephrine. Inhibition of catechol-O-methyltransferase. Journal of Medicinal Chemistry. 15: 795-802. PMID 5044295  1
1972 Oesch F, Waters JA, Daly JW, Witkop B. Fluorescent derivatives of strophanthidin. Interaction with sodium- and potassium-activated adenosine triphosphatase. Journal of Medicinal Chemistry. 15: 757-9. PMID 4261402  1
1972 Daly JW, Jerina DM, Witkop B. Arene oxides and the NIH shift: the metabolism, toxicity and carcinogenicity of aromatic compounds. Experientia. 28: 1129-49. PMID 4117670 DOI: 10.1007/BF01946135  1
1971 Jerina DM, Daly JW, Witkop B. Migration of substituents during Hydroxylation of aromatic substrates (NIH shift). Oxidations with peroxytrifluoroacetic acid. Biochemistry. 10: 366-72. PMID 5543961 DOI: 10.1021/bi00779a002  1
1971 Daly JW, Karle I, Myers CW, Tokuyama T, Waters JA, Witkop B. Histrionicotoxins: roentgen-ray analysis of the novel allenic and acetylenie spiroalkaloids isolated from a Colombian frog, Dendrobates histrionicus. Proceedings of the National Academy of Sciences of the United States of America. 68: 1870-5. PMID 5288773 DOI: 10.1073/PNAS.68.8.1870  1
1971 Albuquerque EX, Daly JW, Witkop B. Batrachotoxin: chemistry and pharmacology. Science (New York, N.Y.). 172: 995-1002. PMID 4324825  0.72
1970 Jerina DM, Daly JW, Witkop B, Zaltzman-Nirenberg P, Udenfriend S. 1,2-naphthalene oxide as an intermediate in the microsomal hydroxylation of naphthalene. Biochemistry. 9: 147-56. PMID 5411205 DOI: 10.1021/bi00803a019  1
1970 Daly JW, Jerina DM, Ziffer H, Witkop B, Klärner FG, Vogel E. Enzymatic hydration of 8,9-indan oxide, Homoallylic addition of water. Journal of the American Chemical Society. 92: 702-3. PMID 5411062 DOI: 10.1021/ja00706a048  1
1970 Usubillaga A, Seelkopf C, Karle IL, Daly JW, Witkop B. The structure of solaphyllidine, a novel 4-ketosteroidal alkaloid. Journal of the American Chemical Society. 92: 700-1. PMID 5411061  1
1969 Karle IL, Daly JW, Witkop B. 2,3-cis-3,4-trans-3,4-dihydroxy-L-proline: mass spectrometry and X-ray analysis. Science (New York, N.Y.). 164: 1401-2. PMID 5783710  0.56
1969 Creveling CR, Daly JW, Tokuyama T, Witkop B. Labile lipophilic derivatives of norepinephrine capable of crossing the blood-brain barrier. Experientia. 25: 26-7. PMID 5766567 DOI: 10.1007/BF01903871  1
1969 Daly JW, Tokuyama T, Habermehl G, Karle I, Witkop B. [Frog venoms. Isolation and structure of pumiliotoxin]. Justus Liebigs Annalen Der Chemie. 729: 198-204. PMID 5364747 DOI: 10.1002/JLAC.19697290124  0.72
1968 Daly JW, Guroff G, Jerina DM, Udenfriend S, Witkop B. Intramolecular migrations of aryl substituents during enzymatic hydroxylation. Hoppe-Seyler's Zeitschrift FüR Physiologische Chemie. 349: 1600-4. PMID 5745910  1
1968 Spector S, Tabei R, Creveling CR, Daly JW, Witkop B, Sjoerdsma A. Reduction of tissue norepinephrine and blood pressure by 3,5-dihydroxy-4-methoxy-phenylalanine. Life Sciences. 7: 943-9. PMID 5735321  1
1968 Jerina DM, Daly JW, Witkop B, Zaltzman-Nirenberg P, Udenfriend S. The role of arene oxide-oxepin systems in the metabolism of aromatic substrates. 3. Formation of 1,2-naphthalene oxide from naphthalene by liver microsomes. Journal of the American Chemical Society. 90: 6525-7. PMID 5682453 DOI: 10.1021/ja01025a058  1
1968 Jerina DM, Daly JW, Witkop B. The role of arene oxide-oxepin systems in the metabolism of aromatic substrates. II. Synthesis of 3,4-toluene-4-2H oxide and subsequent "NIH shift" to 4-hydroxytoluene-3-2H. Journal of the American Chemical Society. 90: 6523-5. PMID 5682452 DOI: 10.1021/ja01025a057  0.56
1968 Creveling CR, Daly JW, Parfitt RT, Witkop B. The chemorelease of norepinephrine from mouse hearts. IV. Structure-activity relationships. Reserpines and yohimbines. Journal of Medicinal Chemistry. 11: 596-8. PMID 5656504  1
1968 Creveling CR, Daly JW, Witkop B. The chemorelease of norepinephrine from mouse hearts. 3. 3,5-Dihydroxy-4-methoxyphenethylamines and related compounds. Journal of Medicinal Chemistry. 11: 595-6. PMID 5656503  1
1968 Daly JW, Guroff G, Udenfriend S, Witkop B. Hydroxylation of alkyl and halogen substituted anilines and acetanilides by microsomal hydroxylases. Biochemical Pharmacology. 17: 31-6. PMID 5638557  1
1967 Creveling CR, Daly JW, Witkop B. The depletion of cardiac norepinephrine by 3,5-dihydroxy-4-methoxyphenethylamine and related compounds. The Journal of Pharmacology and Experimental Therapeutics. 158: 46-54. PMID 6054080  0.64
1967 Guroff G, Daly JW, Jerina DM, Renson J, Witkop B, Udenfriend S. Hydroxylation-induced migration: the NIH shift. Recent experiments reveal an unexpected and general result of enzymatic hydroxylation of aromatic compounds. Science (New York, N.Y.). 157: 1524-30. PMID 6038165 DOI: 10.1126/science.157.3796.1524  0.72
1967 Daly JW, Witkop B. Selective exchange of nuclear protons in hydroxyindoles. Journal of the American Chemical Society. 89: 1032-3. PMID 5298577  1
1967 Daly JW, Mauger AB, Yonemitsu O, Antonov VK, Takase K, Witkop B. The synthesis and metabolism of 2,3-dihydro-L-tryptophan and 2,3-dihydro-5-hydroxy-DL-tryptophan. Biochemistry. 6: 648-54. PMID 5297946  1
1966 Creveling CR, Daly JW, Witkop B. The depletion of norepinephrine-3H from heart by alpha-methyl-m-tyrosine. A novel and convenient method for assaying the inhibition of aromatic amino acid decarboxylase in vivo. Journal of Medicinal Chemistry. 9: 284-6. PMID 5960888  1
1966 Daly JW, Creveling CR, Witkop B. The chemorelease of norepinephrine from mouse hearts. Structure-activity relationships. I. Sympathomimetic and related amines. Journal of Medicinal Chemistry. 9: 273-80. PMID 5960887  1
1960 DALY JW, AXELROD J, WITKOP B. Dynamic aspects of enzymatic O-methylation and -demethylation of catechols in vitro and in vivo. The Journal of Biological Chemistry. 235: 1155-9. PMID 13813871  1
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