Jack W. Szostak - Related publications

Genetics Harvard Medical School, Boston, MA, United States 
origin of life
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Staroseletz Y, Amirloo B, Williams A, Lomzov A, Burusco KK, Clarke DJ, Brown T, Zenkova MA, Bichenkova EV. Strict conformational demands of RNA cleavage in bulge-loops created by peptidyl-oligonucleotide conjugates. Nucleic Acids Research. PMID 33010175 DOI: 10.1093/nar/gkaa780   
2020 Micura R, Höbartner C. Fundamental studies of functional nucleic acids: aptamers, riboswitches, ribozymes and DNAzymes. Chemical Society Reviews. PMID 32944725 DOI: 10.1039/d0cs00617c   
2020 Lin J, Liu Y, Lai P, Ye H, Xu L. Conditional guide RNA through two intermediate hairpins for programmable CRISPR/Cas9 function: building regulatory connections between endogenous RNA expressions. Nucleic Acids Research. PMID 33068434 DOI: 10.1093/nar/gkaa842   
2020 Song EY, Jiménez EI, Lin H, Le Vay K, Krishnamurthy R, Mutschler H. Prebiotically plausible RNA activation compatible with ribozyme-catalyzed ligation. Angewandte Chemie (International Ed. in English). PMID 33128282 DOI: 10.1002/anie.202010918   
2020 Velema WA, Kool ET. The chemistry and applications of RNA 2'-OH acylation. Nature Reviews. Chemistry. 4: 22-37. PMID 32984545 DOI: 10.1038/s41570-019-0147-6   
2020 Dai H, Gu W. Strategies and Best Practice in Cloning Small RNAs. Gene Technology. 9. PMID 32953938   
2020 Chandrasekaran AR, Mathivanan J, Ebrahimi P, Vilcapoma J, Chen AA, Halvorsen K, Sheng J. Hybrid DNA/RNA nanostructures with 2'-5' linkages. Nanoscale. PMID 33089274 DOI: 10.1039/d0nr05846g   
2020 Scheitl CPM, Ghaem Maghami M, Lenz AK, Höbartner C. Site-specific RNA methylation by a methyltransferase ribozyme. Nature. PMID 33116304 DOI: 10.1038/s41586-020-2854-z   
2020 Gómez-González B, Aguilera A. Origin matters: spontaneous DNA-RNA hybrids do not form in trans as a source of genome instability. Current Genetics. PMID 33095299 DOI: 10.1007/s00294-020-01117-4   
2020 Tarashima NS, Matsuo A, Minakawa N. Gene Expression of 4'-Thioguanine DNA via 4'-Thiocytosine RNA. Journal of the American Chemical Society. PMID 33016701 DOI: 10.1021/jacs.0c07145   
2020 Galizi R, Duncan JN, Rostain W, Quinn CM, Storch M, Kushwaha M, Jaramillo A. Engineered RNA-Interacting CRISPR Guide RNAs for Genetic Sensing and Diagnostics. The Crispr Journal. 3: 398-408. PMID 33095053 DOI: 10.1089/crispr.2020.0029   
2020 Zajaczkowski EL, Bredy TW. Circular RNAs in the Brain: A Possible Role in Memory? The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 1073858420963028. PMID 33034238 DOI: 10.1177/1073858420963028   
2020 Ehrhardt JE, Weeks KM. Time-Resolved, Single-Molecule, Correlated Chemical Probing of RNA. Journal of the American Chemical Society. PMID 33095984 DOI: 10.1021/jacs.0c06221   
2020 Kelly ML, Chu CC, Shi H, Ganser LR, Bogerd HP, Huynh K, Hou Y, Cullen BR, Al-Hashimi HM. Understanding the characteristics of nonspecific binding of drug-like compounds to canonical stem-loop RNAs and their implications for functional cellular assays. Rna (New York, N.Y.). PMID 33028652 DOI: 10.1261/rna.076257.120   
2020 Ancar R, Li Y, Kindler E, Cooper DA, Ransom M, Thiel V, Weiss SR, Hesselberth JR, Barton DJ. Physiologic RNA Targets and Refined Sequence Specificity of Coronavirus EndoU. Rna (New York, N.Y.). PMID 32989044 DOI: 10.1261/rna.076604.120   
2020 Martín AL, Mounir M, Meyer IM. CoBold: a method for identifying different functional classes of transient RNA structure features that can impact RNA structure formation in vivo. Nucleic Acids Research. PMID 33095878 DOI: 10.1093/nar/gkaa900   
2020 Fraga de Andrade I, Mehta C, Bresnick EH. Post-transcriptional control of cellular differentiation by the RNA exosome complex. Nucleic Acids Research. PMID 33119769 DOI: 10.1093/nar/gkaa883   
2020 Cao D, Gao Y, Roesler C, Rice S, D'Cunha P, Zhuang L, Slack J, Antonova A, Romanelli S, Liang B. primer-based RNA elongation and promoter fine mapping of the respiratory syncytial virus. Journal of Virology. PMID 33028717 DOI: 10.1128/JVI.01897-20   
2020 Rodriques SG, Chen LM, Liu S, Zhong ED, Scherrer JR, Boyden ES, Chen F. RNA timestamps identify the age of single molecules in RNA sequencing. Nature Biotechnology. PMID 33077959 DOI: 10.1038/s41587-020-0704-z   
2020 Marina RJ, Brannan KW, Dong KD, Yee BA, Yeo GW. Evaluation of Engineered CRISPR-Cas-Mediated Systems for Site-Specific RNA Editing. Cell Reports. 33: 108350. PMID 33147453 DOI: 10.1016/j.celrep.2020.108350   
2020 Vågbø CB, Slupphaug G. RNA in DNA repair. Dna Repair. 95: 102927. PMID 32920299 DOI: 10.1016/j.dnarep.2020.102927   
2020 Xu Z. Can the novel coronavirus be transmitted via RNAs without protein capsids? Journal of Infection in Developing Countries. 14: 1001-1003. PMID 33031088 DOI: 10.3855/jidc.13880   
2020 Ravi P, Singh SP, Kang JW, Tran S, Dasari RR, So PTC, Liepmann D, Katti KS, Katti DR, Renugopalakrishnan V, Paulmurugan R. Spectrochemical Probing of microRNA duplex using spontaneous Raman Spectroscopy for Biosensing Applications. Analytical Chemistry. PMID 32985868 DOI: 10.1021/acs.analchem.0c02401   
2020 Gudanis D, Kaniowski D, Kulik K, Baranowski D, Gdaniec Z, Nawrot B. Formation of an RNA Quadruplex-Duplex Hybrid in Living Cells between mRNA of the Epidermal Growth Factor Receptor (EGFR) and a G-Rich Antisense Oligoribonucleotide. Cells. 9. PMID 33138194 DOI: 10.3390/cells9112375   
2020 Jones RA, Steckelberg AL, Vicens Q, Szucs MJ, Akiyama BM, Kieft JS. Different tertiary interactions create the same important 3-D features in a distinct flavivirus xrRNA. Rna (New York, N.Y.). PMID 33004436 DOI: 10.1261/rna.077065.120   
2020 Malina J, Farrell NP, Brabec V. Substitution-Inert Polynuclear Platinum Complexes Inhibit Reverse Transcription Preferentially in RNA Triplex-Forming Templates. Inorganic Chemistry. 59: 15135-15143. PMID 32988198 DOI: 10.1021/acs.inorgchem.0c02070   
2020 Aw JGA, Lim SW, Wang JX, Lambert FRP, Tan WT, Shen Y, Zhang Y, Kaewsapsak P, Li C, Ng SB, Vardy LA, Tan MH, Nagarajan N, Wan Y. Determination of isoform-specific RNA structure with nanopore long reads. Nature Biotechnology. PMID 33106685 DOI: 10.1038/s41587-020-0712-z   
2020 Li P, Zhou X, Xu K, Zhang QC. RASP: an atlas of transcriptome-wide RNA secondary structure probing data. Nucleic Acids Research. PMID 33068412 DOI: 10.1093/nar/gkaa880   
2020 Becette OB, Zong G, Chen B, Taiwo KM, Case DA, Dayie TK. Solution NMR readily reveals distinct structural folds and interactions in doubly C- and F-labeled RNAs. Science Advances. 6. PMID 33028531 DOI: 10.1126/sciadv.abc6572   
2020 Aguilar LC, Paul B, Reiter T, Gendron L, Arul Nambi Rajan A, Montpetit R, Trahan C, Pechmann S, Oeffinger M, Montpetit B. Altered rRNA processing disrupts nuclear RNA homeostasis via competition for the poly(A)-binding protein Nab2. Nucleic Acids Research. PMID 33137177 DOI: 10.1093/nar/gkaa964   
2020 Gassner FJ, Zaborsky N, Buchumenski I, Levanon EY, Gatterbauer M, Schubert M, Rauscher S, Hebenstreit D, Nadeu F, Campo E, Egle A, Greil R, Geisberger R. RNA editing contributes to epitranscriptome diversity in chronic lymphocytic leukemia. Leukemia. PMID 32728184 DOI: 10.1038/s41375-020-0995-6   
2020 Chen L, Yang R, Kwan T, Tang C, Watt S, Zhang Y, Bourque G, Ge B, Downes K, Frontini M, Ouwehand WH, Lin JW, Soranzo N, Pastinen T, Chen L. Paired rRNA-depleted and polyA-selected RNA sequencing data and supporting multi-omics data from human T cells. Scientific Data. 7: 376. PMID 33168820 DOI: 10.1038/s41597-020-00719-4   
2020 Thakur J, Henikoff S. Architectural RNA in chromatin organization. Biochemical Society Transactions. PMID 32897323 DOI: 10.1042/BST20191226   
2020 Choudhury P, Kretschmer J, Hackert P, Bohnsack KE, Bohnsack MT. The DExD box ATPase DDX55 is recruited to domain IV of the 28S ribosomal RNA by its C-terminal region. Rna Biology. 1-12. PMID 33048000 DOI: 10.1080/15476286.2020.1829366   
2020 Dou Y, Kalmykova S, Pashkova M, Oghbaie M, Jiang H, Molloy KR, Chait BT, Rout MP, Fenyö D, Jensen TH, Altukhov I, LaCava J. Affinity proteomic dissection of the human nuclear cap-binding complex interactome. Nucleic Acids Research. PMID 32960270 DOI: 10.1093/nar/gkaa743   
2020 Dasgupta T, Ferdous S, Tse-Dinh YC. Mechanism of Type IA Topoisomerases. Molecules (Basel, Switzerland). 25. PMID 33080770 DOI: 10.3390/molecules25204769   
2020 Pilsl S, Morgan C, Choukeife M, Möglich A, Mayer G. Optoribogenetic control of regulatory RNA molecules. Nature Communications. 11: 4825. PMID 32973178 DOI: 10.1038/s41467-020-18673-5   
2020 Haniff HS, Tong Y, Liu X, Chen JL, Suresh BM, Andrews RJ, Peterson JM, O'Leary CA, Benhamou RI, Moss WN, Disney MD. Targeting the SARS-CoV-2 RNA Genome with Small Molecule Binders and Ribonuclease Targeting Chimera (RIBOTAC) Degraders. Acs Central Science. 6: 1713-1721. PMID 33140033 DOI: 10.1021/acscentsci.0c00984   
2020 King JJ, Larijani M. Structural plasticity of substrate selection by activation-induced cytidine deaminase as a regulator of its genome-wide mutagenic activity. Febs Letters. PMID 33089497 DOI: 10.1002/1873-3468.13962   
2020 de Felippes FF, Waterhouse PM. The Whys and Wherefores of Transitivity in Plants. Frontiers in Plant Science. 11: 579376. PMID 32983223 DOI: 10.3389/fpls.2020.579376   
2020 Davidson L, Francis L, Eaton JD, West S. Integrator-Dependent and Allosteric/Intrinsic Mechanisms Ensure Efficient Termination of snRNA Transcription. Cell Reports. 33: 108319. PMID 33113359 DOI: 10.1016/j.celrep.2020.108319   
2020 Caruso IP, Guimarães GC, Machado VB, Fossey MA, Willbold D, Almeida FCL, Souza FP. Biophysical and dynamic characterization of a fine-tuned binding of the human Respiratory Syncytial Virus M2-1 core domain to long RNAs. Journal of Virology. PMID 32938771 DOI: 10.1128/JVI.01505-20   
2020 Temple MD. Real-time audio and visual display of the Coronavirus genome. Bmc Bioinformatics. 21: 431. PMID 33008363 DOI: 10.1186/s12859-020-03760-7   
2020 Todd LA, Hall AC, Pietrobon V, Chan JNY, Laflamme G, Mekhail K. RNA-cDNA hybrids mediate transposition via different mechanisms. Scientific Reports. 10: 16034. PMID 32994470 DOI: 10.1038/s41598-020-73018-y   
2020 Wang Y, Fang X, Yin H, Zhou Y, Yang Y, Ai S. Photoelectrochemical immunosensor for methylated RNA detection based on WS and poly(U) polymerase-triggered signal amplification. Mikrochimica Acta. 187: 596. PMID 33033870 DOI: 10.1007/s00604-020-04572-5   
2020 Ni WJ, Xie F, Leng XM. Terminus-Associated Non-coding RNAs: Trash or Treasure? Frontiers in Genetics. 11: 552444. PMID 33101379 DOI: 10.3389/fgene.2020.552444   
2020 Yang C, Hu Y, Zhou B, Bao Y, Li Z, Gong C, Yang H, Wang S, Xiao Y. The role of mA modification in physiology and disease. Cell Death & Disease. 11: 960. PMID 33162550 DOI: 10.1038/s41419-020-03143-z   
2020 Jensen D, Galburt EA. The Context-Dependent Influence of Promoter Sequence Motifs on Transcription Initiation Kinetics and Regulation. Journal of Bacteriology. PMID 33139481 DOI: 10.1128/JB.00512-20   
2020 Porto EM, Komor AC, Slaymaker IM, Yeo GW. Base editing: advances and therapeutic opportunities. Nature Reviews. Drug Discovery. PMID 33077937 DOI: 10.1038/s41573-020-0084-6   
2020 Huang PJ, Liu J. In vitro Selection of Chemically Modified DNAzymes. Chemistryopen. 9: 1046-1059. PMID 33101831 DOI: 10.1002/open.202000134