Thomas H. Scheuermann, Ph.D. - Publications

2004 Yale University, New Haven, CT 
General Biophysics, Biochemistry

10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Yin J, Babaoglu K, Brautigam CA, Clark L, Shao Z, Scheuermann TH, Harrell CM, Gotter AL, Roecker AJ, Winrow CJ, Renger JJ, Coleman PJ, Rosenbaum DM. Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors. Nature Structural & Molecular Biology. PMID 26950369 DOI: 10.1038/Nsmb.3183  0.356
2015 Scheuermann TH, Padrick SB, Gardner KH, Brautigam CA. On the acquisition and analysis of microscale thermophoresis data. Analytical Biochemistry. PMID 26739938 DOI: 10.1016/J.Ab.2015.12.013  0.539
2015 Scheuermann TH, Stroud D, Sleet CE, Bayeh L, Shokri C, Wang H, Caldwell CG, Longgood J, MacMillan JB, Bruick RK, Gardner KH, Tambar UK. Isoform-Selective and Stereoselective Inhibition of Hypoxia Inducible Factor-2. Journal of Medicinal Chemistry. PMID 26226049 DOI: 10.1021/Acs.Jmedchem.5B00529  0.698
2015 Guo Y, Scheuermann TH, Partch CL, Tomchick DR, Gardner KH. Coiled-coil coactivators play a structural role mediating interactions in hypoxia-inducible factor heterodimerization. The Journal of Biological Chemistry. 290: 7707-21. PMID 25627682 DOI: 10.1074/Jbc.M114.632786  0.637
2013 Scheuermann TH, Li Q, Ma HW, Key J, Zhang L, Chen R, Garcia JA, Naidoo J, Longgood J, Frantz DE, Tambar UK, Gardner KH, Bruick RK. Allosteric inhibition of hypoxia inducible factor-2 with small molecules. Nature Chemical Biology. 9: 271-6. PMID 23434853 DOI: 10.1038/Nchembio.1185  0.72
2013 Rogers JL, Bayeh L, Scheuermann TH, Longgood J, Key J, Naidoo J, Melito L, Shokri C, Frantz DE, Bruick RK, Gardner KH, MacMillan JB, Tambar UK. Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor. Journal of Medicinal Chemistry. 56: 1739-47. PMID 23363003 DOI: 10.1021/Jm301847Z  0.72
2009 Key J, Scheuermann TH, Anderson PC, Daggett V, Gardner KH. Principles of ligand binding within a completely buried cavity in HIF2α PAS-B Journal of the American Chemical Society. 131: 17647-17654. PMID 19950993 DOI: 10.1021/Ja9073062  0.697
2009 Scheuermann TH, Tomchick DR, Machius M, Guo Y, Bruick RK, Gardner KH. Artificial ligand binding within the HIF2α PAS-B domain of the HIF2 transcription factor Proceedings of the National Academy of Sciences of the United States of America. 106: 450-455. PMID 19129502 DOI: 10.1073/Pnas.0808092106  0.725
2007 Scheuermann TH, Yang J, Zhang L, Gardner KH, Bruick RK. Hypoxia-Inducible Factors Per/ARNT/Sim Domains: Structure and Function Methods in Enzymology. 435: 1,3-24. PMID 17998046 DOI: 10.1016/S0076-6879(07)35001-5  0.646
2003 Scheuermann TH, Lolis E, Hodsdon ME. Tertiary structure of thiopurine methyltransferase from Pseudomonas syringae, a bacterial orthologue of a polymorphic, drug-metabolizing enzyme. Journal of Molecular Biology. 333: 573-85. PMID 14556746 DOI: 10.1016/J.Jmb.2003.08.039  0.513
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