Duxin Sun, Ph.D. - Publications

2002 University of Michigan, Ann Arbor, Ann Arbor, MI 
Pharmaceutical Chemistry, Pharmacology

286 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Luan X, Yuan H, Song Y, Hu H, Wen B, He M, Zhang H, Li Y, Li F, Shu P, Burnett JP, Truchan N, Palmisano M, Pai MP, Zhou S, ... ... Sun D, et al. Reappraisal of anticancer nanomedicine design criteria in three types of preclinical cancer models for better clinical translation. Biomaterials. 275: 120910. PMID 34144373 DOI: 10.1016/j.biomaterials.2021.120910  0.88
2021 Zhou H, Bai L, Xu R, McEachern D, Chinnaswamy K, Li R, Wen B, Wang M, Yang CY, Meagher JL, Sun D, Stuckey JA, Wang S. SD-91 as A Potent and Selective STAT3 Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression. Acs Medicinal Chemistry Letters. 12: 996-1004. PMID 34141084 DOI: 10.1021/acsmedchemlett.1c00155  0.64
2021 Rogawski DS, Deng J, Li H, Miao H, Borkin D, Purohit T, Song J, Chase J, Li S, Ndoj J, Klossowski S, Kim E, Mao F, Zhou B, Ropa J, ... ... Sun D, et al. Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity. Nature Communications. 12: 2792. PMID 33990599 DOI: 10.1038/s41467-021-23152-6  0.88
2021 Wang Y, Xie Y, Niu Y, Song P, Liu Y, Burnett J, Yang Z, Sun D, Ran Y, Li Y, Sun L. Carboxypeptidase A4 negatively correlates with p53 expression and regulates the stemness of breast cancer cells. International Journal of Medical Sciences. 18: 1753-1759. PMID 33746592 DOI: 10.7150/ijms.54954  0.88
2021 Wang H, Ong E, Kao JY, Sun D, He Y. Reverse Microbiomics: A New Reverse Dysbiosis Analysis Strategy and Its Usage in Prediction of Autoantigens and Virulent Factors in Dysbiotic Gut Microbiomes From Rheumatoid Arthritis Patients. Frontiers in Microbiology. 12: 633732. PMID 33717026 DOI: 10.3389/fmicb.2021.633732  0.8
2021 Liu Y, Hur J, Chan WKB, Wang Z, Xie J, Sun D, Handelman S, Sexton J, Yu H, He Y. Ontological modeling and analysis of experimentally or clinically verified drugs against coronavirus infection. Scientific Data. 8: 16. PMID 33441564 DOI: 10.1038/s41597-021-00799-w  0.88
2020 Huddle BC, Grimley E, Chtcherbinine M, Buchman CD, Takahashi C, Debnath B, McGonigal SC, Mao S, Li S, Felton J, Pan S, Wen B, Sun D, Neamati N, Buckanovich RJ, et al. Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy. European Journal of Medicinal Chemistry. 211: 113060. PMID 33341649 DOI: 10.1016/j.ejmech.2020.113060  0.6
2020 Rom O, Liu Y, Liu Z, Zhao Y, Wu J, Ghrayeb A, Villacorta L, Fan Y, Chang L, Wang L, Liu C, Yang D, Song J, Rech JC, Guo Y, ... ... Sun D, et al. Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome. Science Translational Medicine. 12. PMID 33268508 DOI: 10.1126/scitranslmed.aaz2841  0.88
2020 Chen J, Zhou Y, Dong X, Liu L, Bai L, McEachern D, Przybranowski S, Yang CY, Stuckey J, Li X, Wen B, Zhao T, Sun S, Sun D, Jiao L, et al. Discovery of CJ-2360 as a Potent and Orally Active Inhibitor of Anaplastic Lymphoma Kinase Capable of Achieving Complete Tumor Regression. Journal of Medicinal Chemistry. PMID 33185101 DOI: 10.1021/acs.jmedchem.0c01550  0.64
2020 Wilson MW, Shu L, Hinkovska-Galcheva V, Jin Y, Rajeswaran W, Abe A, Zhao T, Luo R, Wang L, Wen B, Liou B, Fannin V, Sun D, Sun Y, Shayman JA, et al. Optimization of Eliglustat-Based Glucosylceramide Synthase Inhibitors as Substrate Reduction Therapy for Gaucher Disease Type 3. Acs Chemical Neuroscience. PMID 33035424 DOI: 10.1021/acschemneuro.0c00558  0.6
2020 Sun D, Zhou S, Gao W. What Went Wrong with Anticancer Nanomedicine Design and How to Make It Right. Acs Nano. PMID 33021091 DOI: 10.1021/acsnano.9b09713  0.56
2020 Bailey CM, Liu Y, Peng G, Zhang H, He M, Sun D, Zheng P, Liu Y, Wang Y. Liposomal formulation of HIF-1α inhibitor Echinomycin eliminates established metastases of triple-negative breast Cancer. Nanomedicine : Nanotechnology, Biology, and Medicine. 102278. PMID 32738299 DOI: 10.1016/J.Nano.2020.102278  0.88
2020 Li Y, Palmisano M, Sun D, Zhou S. Pharmacokinetic Disposition Difference Between Cyclosporine and Voclosporin Drives Their Distinct Efficacy and Safety Profiles in Clinical Studies. Clinical Pharmacology : Advances and Applications. 12: 83-96. PMID 32669879 DOI: 10.2147/CPAA.S255789  0.68
2020 Rej RK, Wang C, Lu J, Wang M, Petrunak E, Zawacki KP, McEachern D, Fernandez-Salas E, Yang CY, Wang L, Li R, Chinnaswamy K, Wen B, Sun D, Stuckey J, et al. EEDi-5285: An Exceptionally Potent, Efficacious, and Orally Active Small-Molecule Inhibitor of Embryonic Ectoderm Development. Journal of Medicinal Chemistry. PMID 32580550 DOI: 10.1021/Acs.Jmedchem.0C00479  0.76
2020 Yuan H, Guo H, Luan X, He M, Li F, Burnett J, Truchan N, Sun D. Albumin Nanoparticle of Paclitaxel (Abraxane) Decreases while Taxol Increases Breast Cancer Stem Cells in Treatment of Triple Negative Breast Cancer. Molecular Pharmaceutics. PMID 32485107 DOI: 10.1021/Acs.Molpharmaceut.9B01221  0.88
2020 Gasparyan M, Lo MC, Jiang H, Lin CC, Sun D. Combined P53/PTEN deficiency activates expression of mesenchyme homeobox 1 (MEOX1) required for growth of triple-negative breast cancer. The Journal of Biological Chemistry. PMID 32467227 DOI: 10.1074/Jbc.Ra119.010710  0.64
2020 Liu X, Wilson MW, Liu K, Lee P, Yeomans L, Hagen SE, Lin CM, Wen B, Sun D, White AD, Showalter HD, Antonetti DA. Synthesis and structure-activity relationships of thieno[2,3-d]pyrimidines as atypical protein kinase C inhibitors to control retinal vascular permeability and cytokine-induced edema. Bioorganic & Medicinal Chemistry. 115480. PMID 32327351 DOI: 10.1016/J.Bmc.2020.115480  0.6
2020 Lin CC, Lo MC, Moody R, Jiang H, Harouaka R, Stevers N, Tinsley S, Gasparyan M, Wicha M, Sun D. Corrigendum to "Targeting LRP8 inhibits breast cancer stem cells in triple-negative breast cancer" [Canc. Lett. 438 (2018, Dec 1) 165-173]. Cancer Letters. PMID 32229161 DOI: 10.1016/J.Canlet.2020.01.013  0.64
2020 Ji X, Xie S, Jiao Y, Zhang X, Sun D, Yang VC, Wang M, He H, Sun L. MT1-MMP activatable fluorogenic probes with enhanced specificity via high-affinity peptide conjugation for tumor imaging. Biomaterials Science. PMID 32186291 DOI: 10.1039/C9Bm02007A  0.76
2020 Wang Y, Liu Y, Bailey C, Zhang H, He M, Sun D, Zhang P, Parkin B, Baer MR, Zheng P, Malek SN, Liu Y. Therapeutic targeting of TP53-mutated acute myeloid leukemia by inhibiting HIF-1α with echinomycin. Oncogene. PMID 32060420 DOI: 10.1038/S41388-020-1201-Z  0.88
2020 Zwicker JD, Smith D, Guerra AJ, Hitchens JR, Haug N, Vander Roest S, Lee P, Wen B, Sun D, Wang L, Keep R, Xiang J, Carruthers VB, Larsen SD. Discovery and Optimization of Triazine Nitrile Inhibitors of Toxoplasma gondii Cathepsin L for the Potential Treatment of Chronic Toxoplasmosis in the CNS. Acs Chemical Neuroscience. PMID 32027110 DOI: 10.1021/Acschemneuro.9B00674  0.48
2020 Chen H, Luan X, Paholak HJ, Burnett JP, Stevers NO, Sansanaphongpricha K, He M, Chang AE, Li Q, Sun D. Depleting tumor-associated Tregs via nanoparticle-mediated hyperthermia to enhance anti-CTLA-4 immunotherapy. Nanomedicine (London, England). 15: 77-92. PMID 31868112 DOI: 10.2217/Nnm-2019-0190  0.88
2020 Tan YS, Heath BR, Hill BD, Luo X, Rizvi SM, Moghbeli T, Hu H, Siismets E, Wen H, Xie Y, Sun D, Young S, Zou W, Wen F, Lei YL. Abstract A08: Resolving STING-mediated tumor immune microenvironment shift at single-cell resolution Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Aacrahns19-A08  0.84
2020 Burnett JP, Johnson G, Truchan N, Brooks M, Wicha MS, Sun D. Abstract 500: Discovering epigenetic regulators of cells states in triple negative breast cancers Cancer Research. 80: 500-500. DOI: 10.1158/1538-7445.Am2020-500  0.84
2019 Wang Y, Zhao L, Han X, Wang Y, Mi J, Wang C, Sun D, Fu Y, Zhao X, Guo H, Wang Q. Saikosaponin A Inhibits Triple-Negative Breast Cancer Growth and Metastasis Through Downregulation of CXCR4. Frontiers in Oncology. 9: 1487. PMID 32047724 DOI: 10.3389/Fonc.2019.01487  0.88
2019 Klossowski S, Miao H, Kempinska K, Wu T, Purohit T, Kim E, Linhares BM, Chen D, Jih G, Perkey E, Huang H, He M, Wen B, Wang Y, Yu K, ... ... Sun D, et al. Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia. The Journal of Clinical Investigation. PMID 31855575 DOI: 10.1172/JCI129126  0.88
2019 Zhou H, Bai L, Xu R, Zhao Y, Chen J, McEachern D, Chinnaswamy K, Wen B, Dai L, Kumar P, Yang CY, Liu Z, Wang M, Liu L, Meagher JL, ... ... Sun D, et al. Structure-Based Discovery of SD-36 as a Potent, Selective and Efficacious PROTAC Degrader of STAT3 Protein. Journal of Medicinal Chemistry. PMID 31747516 DOI: 10.1021/Acs.Jmedchem.9B01530  0.64
2019 Bai L, Zhou H, Xu R, Zhao Y, Chinnaswamy K, McEachern D, Chen J, Yang CY, Liu Z, Wang M, Liu L, Jiang H, Wen B, Kumar P, Meagher JL, ... Sun D, et al. A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo. Cancer Cell. 36: 498-511.e17. PMID 31715132 DOI: 10.1016/J.Ccell.2019.10.002  0.64
2019 Yu A, Koenigsknecht MJ, Hens B, Baker JR, Wen B, Jackson TL, Pai MP, Hasler W, Amidon GL, Sun D. Mechanistic Deconvolution of Oral Absorption Model with Dynamic Gastrointestinal Fluid to Predict Regional Rate and Extent of GI Drug Dissolution. The Aaps Journal. 22: 3. PMID 31712917 DOI: 10.1208/S12248-019-0385-Z  0.6
2019 Das NK, Schwartz AJ, Barthel G, Inohara N, Liu Q, Sankar A, Hill DR, Ma X, Lamberg O, Schnizlein MK, Arqués JL, Spence JR, Nunez G, Patterson AD, Sun D, et al. Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis. Cell Metabolism. PMID 31708445 DOI: 10.1016/J.Cmet.2019.10.005  0.44
2019 Shu P, Zhao T, Wen B, Mendelsohn-Victor K, Sun D, Friese CR, Pai MP. Application of an innovative high-throughput liquid chromatography-tandem mass spectrometry method for simultaneous analysis of 18 hazardous drugs to rule out accidental acute chemotherapy exposures in health care workers. Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners. 1078155219870591. PMID 31483750 DOI: 10.1177/1078155219870591  0.56
2019 Heath BR, Michmerhuizen NL, Donnelly CR, Sansanaphongpricha K, Sun D, Brenner JC, Lei YL. Head and Neck Cancer Immunotherapy beyond the Checkpoint Blockade. Journal of Dental Research. 22034519864112. PMID 31340724 DOI: 10.1177/0022034519864112  0.56
2019 Chen H, Hu H, Tao C, Clauson RM, Moncion I, Luan X, Hwang S, Sough A, Sansanaphongpricha K, Liao J, Paholak HJ, Stevers NO, Wang G, Liu B, Sun D. Self-Assembled Au@Fe Core/Satellite Magnetic Nanoparticles for Versatile Biomolecule Functionalization. Acs Applied Materials & Interfaces. PMID 31245984 DOI: 10.1021/Acsami.9B05544  0.56
2019 Li F, Yuan H, Zhang H, He M, Liao J, Chen N, Li Y, Zhou S, Palmisano M, Yu A, Pai M, Sun D. Neonatal Fc Receptor (FcRn) Enhances Tissue Distribution and Prevents Excretion of nab-Paclitaxel. Molecular Pharmaceutics. PMID 31002261 DOI: 10.1021/Acs.Molpharmaceut.8B01314  0.88
2019 Kahl D, Hutchings KM, Lisabeth EM, Haak A, Leipprandt JR, Dexheimer TS, Khanna D, Tsou PS, Campbell PL, Fox DA, Wen B, Sun D, Bailie M, Neubig RR, Larsen SD. 5-Aryl-1,3,4-oxadiazol-2-ylthioalkanoic Acids: A Highly Potent New Class of Inhibitors of Rho/Myocardin-Related Transcription Factor (MRTF)/Serum Reponse Factor (SRF)-Mediated Gene Transcription as Potential Antifibrotic Agents for Scleroderma. Journal of Medicinal Chemistry. PMID 30951312 DOI: 10.1021/Acs.Jmedchem.8B01772  0.48
2019 Seekatz AM, Schnizlein MK, Koenigsknecht MJ, Baker JR, Hasler WL, Bleske BE, Young VB, Sun D. Spatial and Temporal Analysis of the Stomach and Small-Intestinal Microbiota in Fasted Healthy Humans. Msphere. 4. PMID 30867328 DOI: 10.1128/mSphere.00126-19  0.6
2019 Gan X, Wilson MW, Beyett TS, Wen B, Sun D, Larsen SD, Tesmer JJG, Saltiel AR, Showalter HD. Synthesis of deuterium-labelled amlexanox and its metabolic stability against mouse, rat and human microsomes. Journal of Labelled Compounds & Radiopharmaceuticals. PMID 30828860 DOI: 10.1002/Jlcr.3716  0.48
2019 Dai W, Samanta S, Xue D, Petrunak EM, Stuckey JA, Han Y, Sun D, Wu Y, Neamati N. Structure-based Design of N-(5-phenylthiazol-2-yl)acrylamides as Novel and Potent Glutathione S-Transferase Omega 1 Inhibitors. Journal of Medicinal Chemistry. PMID 30735370 DOI: 10.2210/Pdb6Mhc/Pdb  0.56
2019 Sun L, Yuan H, Burnett J, Gasparyan M, Zhang Y, Zhang F, Yang Z, Ran Y, Sun D. MEOX1 Promotes Tumor Progression and Predicts Poor Prognosis in Human Non-Small-Cell Lung Cancer. International Journal of Medical Sciences. 16: 68-74. PMID 30662330 DOI: 10.7150/Ijms.27595  0.84
2019 Baker JR, Dickens JR, Koenigsknecht M, Frances A, Lee AA, Shedden KA, Brasseur JG, Amidon GL, Sun D, Hasler WL. Propagation Characteristics of Fasting Duodeno-Jejunal Contractions in Healthy Controls Measured by Clustered Closely-spaced Manometric Sensors. Journal of Neurogastroenterology and Motility. 25: 100-112. PMID 30646481 DOI: 10.5056/Jnm18112  0.6
2019 Chen H, Luan X, Paholak H, Burnett J, Stevers N, Sansanaphongpricha K, He M, Chang A, Li Q, Sun D. Abstract 3220: Enhancing breast cancer immunotherapy via IONP-mediated photothermal therapy Immunology. DOI: 10.1158/1538-7445.Sabcs18-3220  0.88
2019 Truchan NA, Burnett JP, Sun D. Abstract 968: Targeting intratumoral heterogeneity in TNBC with novel combinations of FDA-approved drugs Cancer Research. 79: 968-968. DOI: 10.1158/1538-7445.Am2019-968  0.52
2018 Li YF, Zhang C, Zhou S, He M, Zhang H, Chen N, Li F, Luan X, Pai M, Yuan H, Sun D, Li Y. Species difference in paclitaxel disposition correlated with poor pharmacological efficacy translation from mice to humans. Clinical Pharmacology : Advances and Applications. 10: 165-174. PMID 30519122 DOI: 10.2147/CPAA.S185449  0.88
2018 Paixão P, Bermejo M, Hens B, Tsume Y, Dickens J, Shedden K, Salehi N, Koenigsknecht MJ, Baker JR, Hasler WL, Lionberger R, Fan J, Wysocki J, Wen B, Lee A, ... ... Sun D, et al. Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 2: Fed State. Molecular Pharmaceutics. PMID 30417648 DOI: 10.1021/Acs.Molpharmaceut.8B00736  0.6
2018 Bermejo M, Paixão P, Hens B, Tsume Y, Koenigsknecht MJ, Baker JR, Hasler WL, Lionberger R, Fan J, Dickens J, Shedden KA, Wen B, Wysocki J, Löbenberg R, Lee A, ... ... Sun D, et al. Linking the Gastrointestinal Behavior of Ibuprofen with The Systemic Exposure Between and Within Humans - Part 1: Fasted State. Molecular Pharmaceutics. PMID 30372084 DOI: 10.1021/Acs.Molpharmaceut.8B00515  0.6
2018 Yu J, Chen J, Zhao H, Gao J, Li Y, Li Y, Xue J, Dahan A, Sun D, Zhang G, Zhang H. Integrative proteomics and metabolomics analysis reveals the toxicity of cationic liposomes to human normal hepatocyte cell line L02. Molecular Omics. PMID 30247494 DOI: 10.1039/c8mo00132d  0.88
2018 Lin CC, Lo MC, Moody R, Jiang H, Harouaka R, Stevers N, Tinsley S, Gasparyan M, Wicha M, Sun D. Targeting LRP8 inhibits breast cancer stem cells in triple-negative breast cancer. Cancer Letters. PMID 30227220 DOI: 10.1016/J.Canlet.2018.09.022  0.64
2018 Huddle BC, Grimley E, Buchman CD, Chtcherbinine M, Debnath B, Mehta P, Yang K, Morgan CA, Li S, Felton JA, Sun D, Metha G, Neamati N, Buckanovich RJ, Hurley TD, et al. Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy. Journal of Medicinal Chemistry. PMID 30221940 DOI: 10.1021/Acs.Jmedchem.8B00930  0.36
2018 Tsume Y, Patel S, Fotaki N, Bergstrӧm C, Amidon GL, Brasseur JG, Mudie DM, Sun D, Bermejo M, Gao P, Zhu W, Sperry DC, Vertzoni M, Parrott N, Lionberger R, et al. In Vivo Predictive Dissolution and Simulation Workshop Report: Facilitating the Development of Oral Drug Formulation and the Prediction of Oral Bioperformance. The Aaps Journal. 20: 100. PMID 30191341 DOI: 10.1208/S12248-018-0260-3  0.6
2018 Li F, Zhang H, He M, Liao J, Chen N, Li Y, Zhou S, Palmisano M, Yu A, Pai MP, Yuan H, Sun D. Different nanoformulations alter the tissue distribution of paclitaxel, which aligns with reported distinct efficacy and safety profiles. Molecular Pharmaceutics. PMID 30180593 DOI: 10.1021/Acs.Molpharmaceut.8B00527  0.88
2018 Luan X, Guan YY, Liu HJ, Lu Q, Zhao M, Sun D, Lovell JF, Sun P, Chen HZ, Fang C. A Tumor Vascular-Targeted Interlocking Trimodal Nanosystem That Induces and Exploits Hypoxia. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 5: 1800034. PMID 30128230 DOI: 10.1002/Advs.201800034  0.56
2018 Qin C, Hu Y, Zhou B, Fernandez-Salas E, Yang CY, Liu L, McEachern D, Przybranowski S, Wang M, Stuckey J, Meagher J, Bai L, Chen Z, Lin M, Yang J, ... ... Sun D, et al. Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression. Journal of Medicinal Chemistry. PMID 30019901 DOI: 10.1021/Acs.Jmedchem.8B00506  0.8
2018 Zhao Y, Zhou B, Bai L, Liu L, Yang CY, Meagher JL, Stuckey JA, McEachern D, Przybranowski S, Wang M, Ran X, Aguilar A, Hu Y, Kampf JW, Li X, ... ... Sun D, et al. Structure-Based Discovery of CF53 as a Potent and Orally Bioavailable Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitor. Journal of Medicinal Chemistry. PMID 30015487 DOI: 10.1021/Acs.Jmedchem.8B00483  0.64
2018 Li Y, Cui XL, Chen QS, Yu J, Zhang H, Gao J, Sun DX, Zhang GQ. Cationic liposomes induce cytotoxicity in HepG2 via regulation of lipid metabolism based on whole-transcriptome sequencing analysis. Bmc Pharmacology & Toxicology. 19: 43. PMID 29996945 DOI: 10.1186/S40360-018-0230-5  0.88
2018 Hens B, Sinko P, Job N, Dean M, Al-Gousous J, Salehi N, Ziff RM, Tsume Y, Bermejo M, Paixão P, Brasseur JG, Yu A, Talattof A, Benninghoff G, Langguth P, ... ... Sun D, et al. Formulation Predictive Dissolution (fPD) Testing to Advance Oral Drug Product Development: an Introduction to the US FDA Funded '21 Century BA/BE' Project. International Journal of Pharmaceutics. PMID 29944899 DOI: 10.1016/J.Ijpharm.2018.06.050  0.6
2018 Paixão P, Bermejo M, Hens B, Tsume Y, Dickens J, Shedden K, Salehi N, Koenigsknecht MJ, Baker JR, Hasler WL, Lionberger R, Fan J, Wysocki J, Wen B, Lee A, ... ... Sun D, et al. Gastric Emptying and Intestinal Appearance of Nonabsorbable Drugs Phenol Red and Paromomycin in Human Subjects: A Multi-Compartment Stomach Approach. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 29857136 DOI: 10.1016/J.Ejpb.2018.05.033  0.6
2018 Li W, Tanikawa T, Kryczek I, Xia H, Li G, Wu K, Wei S, Zhao L, Vatan L, Wen B, Shu P, Sun D, Kleer C, Wicha M, Sabel M, et al. Aerobic Glycolysis Controls Myeloid-Derived Suppressor Cells and Tumor Immunity via a Specific CEBPB Isoform in Triple-Negative Breast Cancer. Cell Metabolism. PMID 29805099 DOI: 10.1016/J.Cmet.2018.04.022  0.56
2018 Tan YS, Sansanaphongpricha K, Xie Y, Donnelly CR, Luo X, Heath BR, Zhao X, Bellile EL, Hu H, Chen H, Polverini PJ, Chen Q, Young S, Carey TE, Nör JE, ... ... Sun D, et al. Mitigating SOX2-potentiated immune escape of Head and Neck Squamous Cell Carcinoma with a STING-inducing nanosatellite vaccine. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29769207 DOI: 10.1158/1078-0432.Ccr-17-2807  0.84
2018 Borkin D, Klossowski S, Pollock J, Miao H, Linhares B, Kempinska K, Jin Z, Purohit T, Wen B, He M, Sun D, Cierpicki T, Grembecka J. The complexity of blocking bivalent protein-protein interactions: development of a highly potent inhibitor of the menin-Mixed Lineage Leukemia (MLL) interaction. Journal of Medicinal Chemistry. PMID 29738674 DOI: 10.1021/Acs.Jmedchem.8B00071  0.88
2018 Madak JT, Cuthbertson CR, Miyata Y, Tamura S, Petrunak EM, Stuckey JA, Han Y, He M, Sun D, Showalter HD, Neamati N. Design, Synthesis, and Biological Evaluation of 4-Quinoline Carboxylic Acids as Inhibitors of Dihydroorotate Dehydrogenase. Journal of Medicinal Chemistry. PMID 29727569 DOI: 10.1021/Acs.Jmedchem.7B01862  0.88
2018 Zwicker JD, Diaz NA, Guerra AJ, Kirchhoff PD, Wen B, Sun D, Carruthers VB, Larsen SD. Optimization of dipeptidic inhibitors of cathepsin L for improved Toxoplasma gondii selectivity and CNS permeability. Bioorganic & Medicinal Chemistry Letters. PMID 29650289 DOI: 10.1016/J.Bmcl.2018.03.020  0.48
2018 Lin CC, Lo MC, Moody RR, Stevers NO, Tinsley SL, Sun D. Doxycycline targets aldehyde dehydrogenase‑positive breast cancer stem cells. Oncology Reports. PMID 29620216 DOI: 10.3892/Or.2018.6337  0.64
2018 Tan YS, Sansanaphongpricha K, Prince MEP, Sun D, Wolf GT, Lei YL. Engineering Vaccines to Reprogram Immunity against Head and Neck Cancer. Journal of Dental Research. 22034518764416. PMID 29533731 DOI: 10.1177/0022034518764416  0.56
2018 Luo M, Brooks M, Burnett J, Truchan N, Sun D, Wicha MS. Abstract LB-053: Tracing redox-regulated breast cancer stem cell state transition using a dual fluorescent reporter system Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-053  0.84
2018 Truchan NA, Buschhaus J, Brooks M, Halabu A, Guo H, Yuan H, Luker K, Wicha M, Sun D, Burnett JP. Abstract 2007: A novel CRISPR/Cas9 reporter system to monitor TNBC cancer stem cells in real time Cancer Research. 78: 2007-2007. DOI: 10.1158/1538-7445.Am2018-2007  0.64
2018 Lin C, Lo M, Moody R, Stevers N, Tinsley S, Gasparyan M, Wicha M, Sun D. Abstract 2004: Identification of MLK4 as a novel regulator of cancer stem cells in triple-negative breast cancer Tumor Biology. DOI: 10.1158/1538-7445.Am2018-2004  0.64
2018 Kump KJ, Tong J, Mady AS, Miao L, Li S, Sun D, Yu J, Zhang L, Nikolovska-Coleska Z. Abstract 1970: Novel Mcl-1 inhibitor effectively restores in vivo regorafenib sensitivity in resistant colorectal cancer Cancer Research. 78: 1970-1970. DOI: 10.1158/1538-7445.Am2018-1970  0.52
2017 Moody RR, Lo MC, Meagher JL, Lin CC, Stevers NO, Tinsley SL, Jung I, Matvekas A, Stuckey JA, Sun D. Probing the interaction between the histone methyltransferase/deacetylase subunit RBBP4/7 and the transcription factor BCL11A in epigenetic complexes. The Journal of Biological Chemistry. PMID 29263092 DOI: 10.1074/Jbc.M117.811463  0.64
2017 Ye G, Jiang Y, Yang X, Hu H, Wang B, Sun L, Yang VC, Sun D, Gao W. Smart Nanoparticles Undergo Phase-transition for Enhanced Cellular Uptake and Subsequent Intracellular Drug Release in Tumor Microenvironment. Acs Applied Materials & Interfaces. PMID 29260563 DOI: 10.1021/Acsami.7B15978  0.64
2017 Conner TM, Nikolian VC, Georgoff PE, Pai MP, Alam HB, Sun D, Reed RC, Zhang T. Physiologically based pharmacokinetic modeling of disposition and drug-drug interactions for valproic acid and divalproex. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 29030176 DOI: 10.1016/J.Ejps.2017.10.009  0.56
2017 Yu A, Jackson T, Tsume Y, Koenigsknecht M, Wysocki J, Marciani L, Amidon GL, Frances A, Baker JR, Hasler W, Wen B, Pai A, Sun D. Mechanistic Fluid Transport Model to Estimate Gastrointestinal Fluid Volume and Its Dynamic Change Over Time. The Aaps Journal. PMID 28980204 DOI: 10.1208/S12248-017-0145-X  0.6
2017 Sun D, Baker JR, Wen B, Frances A, Zhang H, Yu A, Zhao T, Tsume Y, Pai M, Bleske B, Zhang X, Lionberger R, Lee A, Amidon G, Hasler WL, et al. In Vivo Dissolution and Systemic Absorption of Immediate Release Ibuprofen in Human Gastrointestinal Tract Under Fed and Fasted Conditions. Molecular Pharmaceutics. PMID 28937221 DOI: 10.1021/Acs.Molpharmaceut.7B00425  0.88
2017 Kick BL, Shu P, Wen B, Sun D, Taylor DK. Pharmacokinetic Profiles of Nalbuphine after Intraperitoneal and Subcutaneous Administration to C57BL/6 Mice. Journal of the American Association For Laboratory Animal Science : Jaalas. 56: 534-538. PMID 28903824  0.56
2017 Sun L, Guo C, Cao J, Burnett J, Yang Z, Ran Y, Sun D. Over-Expression of Alpha-Enolase as a Prognostic Biomarker in Patients with Pancreatic Cancer. International Journal of Medical Sciences. 14: 655-661. PMID 28824297 DOI: 10.7150/Ijms.18736  0.64
2017 Hens B, Tsume Y, Bermejo M, Paixao P, Koenigsknecht M, Baker JR, Hasler WL, Lionberger R, Fan J, Dickens J, Shedden KA, Wen B, Wysocki J, Löbenberg R, Lee A, ... ... Sun D, et al. Low Buffer Capacity and Alternating Motility Along The Human Gastrointestinal Tract: Implications for In Vivo Dissolution and Absorption of Ionizable Drugs. Molecular Pharmaceutics. PMID 28737409 DOI: 10.1021/Acs.Molpharmaceut.7B00426  0.6
2017 Connarn JN, Flowers S, Kelly M, Luo R, Ward KM, Harrington G, Moncion I, Kamali M, McInnis M, Feng MR, Ellingrod V, Babiskin A, Zhang X, Sun D. Pharmacokinetics and Pharmacogenomics of Bupropion in Three Different Formulations with Different Release Kinetics in Healthy Human Volunteers. The Aaps Journal. PMID 28685396 DOI: 10.1208/S12248-017-0102-8  0.76
2017 Yu J, Zhang H, Li Y, Sun S, Gao J, Zhong Y, Sun D, Zhang G. Metabolomics revealed the toxicity of cationic liposomes in HepG2 cells using UHPLC-Q-TOF/MS and multivariate data analysis. Biomedical Chromatography : Bmc. PMID 28664536 DOI: 10.1002/Bmc.4036  0.88
2017 Karatas H, Li Y, Liu L, Ji J, Lee S, Chen Y, Yang J, Huang L, Bernard D, Xu J, Townsend EC, Cao F, Ran X, Li X, Wen B, ... Sun D, et al. Discovery of a Highly Potent, Cell-Permeable Macrocyclic Peptidomimetic (MM-589) Targeting the WD Repeat Domain 5 Protein (WDR5)-Mixed Lineage Leukemia (MLL) Protein-Protein Interaction. Journal of Medicinal Chemistry. PMID 28603984 DOI: 10.1021/Acs.Jmedchem.6B01796  0.68
2017 Georgoff PE, Nikolian VC, Bonham T, Pai MP, Tafatia C, Halaweish I, To K, Watcharotone K, Parameswaran A, Luo R, Sun D, Alam HB. Safety and Tolerability of Intravenous Valproic Acid in Healthy Subjects: A Phase I Dose-Escalation Trial. Clinical Pharmacokinetics. PMID 28497259 DOI: 10.1007/S40262-017-0553-1  0.44
2017 Sun L, Cao J, Guo C, Burnett J, Yang Z, Ran Y, Sun D. Associations of carboxypeptidase 4 with ALDH1A1 expression and their prognostic value in esophageal squamous cell carcinoma. Diseases of the Esophagus : Official Journal of the International Society For Diseases of the Esophagus. 30: 1-5. PMID 28475748 DOI: 10.1093/Dote/Dox011  0.64
2017 Zhao Y, Bai L, Liu L, McEachern D, Stuckey JA, Meagher JL, Yang CY, Ran X, Zhou B, Hu Y, Li X, Wen B, Zhao T, Li S, Sun D, et al. Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor. Journal of Medicinal Chemistry. PMID 28463487 DOI: 10.1021/Acs.Jmedchem.7B00193  0.64
2017 Wang M, Xie F, Wen X, Chen H, Zhang H, Liu J, Zhang H, Zou H, Yu Y, Chen Y, Sun Z, Wang X, Zhang G, Yin C, Sun D, et al. Therapeutic PEG-ceramide nanomicelles synergize with salinomycin to target both liver cancer cells and cancer stem cells. Nanomedicine (London, England). PMID 28440698 DOI: 10.2217/Nnm-2016-0408  1
2017 Luan X, Sansanaphongpricha K, Myers I, Chen H, Yuan H, Sun D. Engineering exosomes as refined biological nanoplatforms for drug delivery. Acta Pharmacologica Sinica. PMID 28392567 DOI: 10.1038/Aps.2017.12  0.64
2017 Aguilar A, Lu J, Liu L, Du D, Bernard D, McEachern D, Przybranowski S, Li X, Luo R, Wen B, Sun D, Wang H, Wen J, Wang G, Zhai Y, et al. Discovery of 4-((3'R,4'S,5'R)-6″-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2″-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3″-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic Acid (AA-115/APG-115): A Potent and Orally Active Murine Double Minute 2 (MDM2) Inhibitor in Clinical Development. Journal of Medicinal Chemistry. PMID 28339198 DOI: 10.1021/Acs.Jmedchem.6B01665  0.8
2017 Zhou B, Hu J, Xu F, Chen Z, Bai L, Fernandez-Salas E, Lin M, Liu L, Yang CY, Zhao Y, McEachern D, Przybranowski S, Wen B, Sun D, Wang S. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression. Journal of Medicinal Chemistry. PMID 28339196 DOI: 10.1021/Acs.Jmedchem.6B01816  0.8
2017 Hutchings KM, Lisabeth EM, Rajeswaran W, Wilson MW, Sorenson RJ, Campbell PL, Ruth JH, Amin A, Tsou PS, Leipprandt JR, Olson SR, Wen B, Zhao T, Sun D, Khanna D, et al. Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma. Bioorganic & Medicinal Chemistry Letters. PMID 28285914 DOI: 10.1016/J.Bmcl.2017.02.070  0.48
2017 Tsume Y, Matsui K, Searls AL, Takeuchi S, Amidon GE, Sun D, Amidon GL. The impact of supersaturation level for oral absorption of BCS class IIb drugs, dipyridamole and ketoconazole, using in vivo predictive dissolution system: Gastrointestinal Simulator (GIS). European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 28263914 DOI: 10.1016/J.Ejps.2017.02.042  0.6
2017 Burnett JP, Lim G, Li Y, Shah RB, Lim R, Paholak HJ, McDermott SP, Sun L, Tsume Y, Bai S, Wicha MS, Sun D, Zhang T. Sulforaphane Enhances the Anticancer Activity of Taxanes against Triple Negative Breast Cancer by Killing Cancer Stem Cells. Cancer Letters. PMID 28254410 DOI: 10.1016/J.Canlet.2017.02.023  0.84
2017 Bai L, Zhou B, Yang CY, Ji J, McEachern D, Przybranowski S, Jiang H, Hu J, Xu F, Zhao Y, Liu L, Fernandez-Salas E, Xu J, Dou Y, Wen B, ... Sun D, et al. Targeted degradation of BET proteins in triple-negative breast cancer. Cancer Research. PMID 28209615 DOI: 10.1158/0008-5472.Can-16-2622  0.64
2017 Guo H, Luo H, Yuan H, Xia Y, Shu P, Huang X, Lu Y, Liu X, Keller ET, Sun D, Deng J, Zhang J. Litchi seed extracts diminish prostate cancer progression via induction of apoptosis and attenuation of EMT through Akt/GSK-3β signaling. Scientific Reports. 7: 41656. PMID 28134352 DOI: 10.1038/Srep41656  0.64
2017 Sun L, Guo C, Burnett J, Pan J, Yang Z, Ran Y, Sun D. Association between expression of Carboxypeptidase 4 and stem cell markers and their clinical significance in liver cancer development. Journal of Cancer. 8: 111-116. PMID 28123604 DOI: 10.7150/Jca.17060  0.8
2017 Dahl JU, Gray MJ, Bazopoulou D, Beaufay F, Lempart J, Koenigsknecht MJ, Wang Y, Baker JR, Hasler WL, Young VB, Sun D, Jakob U. The anti-inflammatory drug mesalamine targets bacterial polyphosphate accumulation. Nature Microbiology. 2: 16267. PMID 28112760 DOI: 10.1038/Nmicrobiol.2016.267  0.88
2017 Luo R, Li Y, He M, Zhang H, Yuan H, Johnson M, Palmisano M, Zhou S, Sun D. Distinct biodistribution of doxorubicin and the altered dispositions mediated by different liposomal formulations. International Journal of Pharmaceutics. PMID 28063903 DOI: 10.1016/J.Ijpharm.2017.01.002  0.88
2017 Burnett JP, Fouladdel S, Truchan N, Azizi E, Wicha M, Sun D. Abstract 940: Altering intratumoral heterogeneity in HER2+ breast cancers with PTEN inactivation and trastuzumab therapy Cancer Research. 77: 940-940. DOI: 10.1158/1538-7445.Am2017-940  0.56
2017 Mahran R, Shu P, Sun D, Brenner DE. Abstract 5257: Cellular pharmacology of curcumin cellular pharmacology of curcumin±piperine Cancer Research. 77: 5257-5257. DOI: 10.1158/1538-7445.Am2017-5257  0.32
2017 Fernandez-Salas E, Chen Z, Lin M, Zhou B, McEachern D, Przybranowski S, Kump K, Peterson LF, Kandarpa M, Hu J, Xu F, Liu L, Bai L, Wen B, Sun D, et al. Abstract 5083: A novel and highly efficacious small-molecule degrader of BET-BRD proteins for the treatment of acute leukemia Cancer Research. 77: 5083-5083. DOI: 10.1158/1538-7445.Am2017-5083  0.8
2017 Wu T, Kessler L, Li S, Purohit T, Li S, Miao H, Linhares B, Hansen R, Kucharski J, Wang Y, Yu K, Kempinska K, Ely T, Klossowski S, Zarieh A, ... ... Sun D, et al. Abstract 5077: A novel small molecule menin-MLL inhibitor for potential treatment of MLL-rearranged leukemias Cancer Research. 77: 5077-5077. DOI: 10.1158/1538-7445.Am2017-5077  0.88
2017 Yuan H, Guo H, Li F, Burnett J, He M, Truchan N, Myers I, Sun D. Abstract 4788: Abraxane eliminates cancer stem cells in triple-negative breast cancers Cancer Research. 77: 4788-4788. DOI: 10.1158/1538-7445.Am2017-4788  0.88
2017 Lin C, Lo M, Moody R, Stevers N, Tinsley S, Wicha M, Sun D. Abstract 4767: Identifying CDCA7 as a novel regulator of tumor-initiating cells in triple-negative breast cancer Cancer Research. 77: 4767-4767. DOI: 10.1158/1538-7445.Am2017-4767  0.56
2017 Stevers NO, Tinsley SL, Moody R, Lin C, Meagher J, Stuckey JA, Lo M, Sun D. Abstract 4495: Elucidating BCL11A’s function in triple negative breast cancer Cancer Research. 77: 4495-4495. DOI: 10.1158/1538-7445.Am2017-4495  0.56
2017 Chen H, Paholak HJ, Luan X, Burnett JP, Stevers NO, Sansanaphongpricha K, Sun D. Abstract 2002: Disrupting immunosuppressive tumor microenvironment via stealthy nanobombs to enhance T-cell anticancer efficacy Cancer Research. 77: 2002-2002. DOI: 10.1158/1538-7445.Am2017-2002  0.56
2016 Huang J, Tao C, Yu Y, Yu F, Zhang H, Gao J, Wang D, Chen Y, Gao J, Zhang G, Zhou G, Liu J, Sun Z, Sun D, Zou H, et al. Simultaneous Targeting of Differentiated Breast Cancer Cells and Breast Cancer Stem Cells by Combination of Docetaxel- and Sulforaphane-Loaded Self-Assembled Poly(D, L-lactide-co-glycolide)/Hyaluronic Acid Block Copolymer-Based Nanoparticles. Journal of Biomedical Nanotechnology. 12: 1463-77. PMID 29337484 DOI: 10.1166/Jbn.2016.2234  1
2016 Yu A, Baker JR, Fioritto AF, Wang Y, Luo R, Li S, Wen B, Bly M, Tsume Y, Koenigsknecht MJ, Zhang X, Lionberger R, Amidon GL, Hasler WL, Sun D. Measurement of in vivo Gastrointestinal Release and Dissolution of Three Locally Acting Mesalamine Formulations in Regions of the Human Gastrointestinal Tract. Molecular Pharmaceutics. PMID 28009518 DOI: 10.1021/Acs.Molpharmaceut.6B00641  0.88
2016 Sun L, Guo C, Yuan H, Burnett J, Pan J, Yang Z, Ran Y, Myers I, Sun D. Overexpression of carboxypeptidase A4 (CPA4) is associated with poor prognosis in patients with gastric cancer. American Journal of Translational Research. 8: 5071-5075. PMID 27904708  0.8
2016 Sansanaphongpricha K, DeSantis MC, Chen H, Cheng W, Sun K, Wen B, Sun D. Multibuilding Block Janus Synthesized by Seed-Mediated Self-Assembly for Enhanced Photothermal Effects and Colored Brownian Motion in an Optical Trap. Small (Weinheim An Der Bergstrasse, Germany). PMID 27873448 DOI: 10.1002/Smll.201602569  0.56
2016 Patel TS, Cinti S, Sun D, Li S, Luo R, Wen B, Gallagher BA, Stevenson JG. Oseltamivir for pandemic influenza preparation: Maximizing the use of an existing stockpile. American Journal of Infection Control. PMID 27816215 DOI: 10.1016/J.Ajic.2016.09.024  0.6
2016 Sun L, Guo C, Burnett J, Yang Z, Ran Y, Sun D. Serum carboxypeptidaseA4 levels predict liver metastasis in colorectal carcinoma. Oncotarget. PMID 27780921 DOI: 10.18632/Oncotarget.12798  0.64
2016 Connarn JN, Luo R, Windak J, Zhang X, Babiskin A, Kelly M, Harrington G, Ellingrod VL, Kamali M, McInnis M, Sun D. Identification of Non-Reported Bupropion Metabolites in Human Plasma. Biopharmaceutics & Drug Disposition. PMID 27723114 DOI: 10.1002/Bdd.2046  0.76
2016 Costa MD, Ashraf NS, Fischer S, Yang Y, Schapka E, Joshi G, McQuade TJ, Dharia RM, Dulchavsky M, Ouyang M, Cook D, Sun D, Larsen MJ, Gestwicki JE, Todi SV, et al. Unbiased screen identifies aripiprazole as a modulator of abundance of the polyglutamine disease protein, ataxin-3. Brain : a Journal of Neurology. PMID 27645800 DOI: 10.1093/Brain/Aww228  0.6
2016 Jia T, Sun Z, Lu Y, Gao J, Zou H, Xie F, Zhang G, Xu H, Sun D, Yu Y, Zhong Y. A dual brain-targeting curcumin-loaded polymersomes ameliorated cognitive dysfunction in intrahippocampal amyloid-β1-42-injected mice. International Journal of Nanomedicine. 11: 3765-75. PMID 27540290 DOI: 10.2147/IJN.S94622  0.8
2016 Zhang H, Lauver DA, Wang H, Sun D, Hollenberg PF, Chen YE, Osawa Y, Eitzman DT. Significant Improvement Of Antithrombotic Responses To Clopidogrel By Use Of A Novel Conjugate As Revealed In An Arterial Model Of Thrombosis. The Journal of Pharmacology and Experimental Therapeutics. PMID 27511819 DOI: 10.1124/Jpet.116.236034  0.36
2016 Paholak HJ, Stevers NO, Chen H, Burnett JP, He M, Korkaya H, McDermott SP, Deol Y, Clouthier SG, Luther T, Li Q, Wicha MS, Sun D. Elimination of epithelial-like and mesenchymal-like breast cancer stem cells to inhibit metastasis following nanoparticle-mediated photothermal therapy. Biomaterials. 104: 145-157. PMID 27450902 DOI: 10.1016/J.Biomaterials.2016.06.045  0.8
2016 Chang Y, Sun D, Zhang Z, Zhang Y, Yao X, Jiang D, Yu Y, Mi L, Chen L, Zhong H, Jiang Y. High Color-Rendering-index Hybrid White LEDs Employing CdSe/ZnS Core/Shell Quantum Dots. Journal of Nanoscience and Nanotechnology. 16: 670-6. PMID 27398506  1
2016 Sun L, Wang Y, Yuan H, Burnett J, Pan J, Yang Z, Ran Y, Myers I, Sun D. CPA4 is a Novel Diagnostic and Prognostic Marker for Human Non-Small-Cell Lung Cancer. Journal of Cancer. 7: 1197-204. PMID 27390594 DOI: 10.7150/Jca.15209  0.8
2016 Sun L, Burnett J, Gasparyan M, Xu F, Jiang H, Lin CC, Myers I, Korkaya H, Liu Y, Connarn J, He H, Zhang N, Wicha MS, Sun D. Novel cancer stem cell targets during epithelial to mesenchymal transition in PTEN-deficient trastuzumab-resistant breast cancer. Oncotarget. PMID 27285982 DOI: 10.18632/Oncotarget.9839  0.88
2016 Yu F, Huang J, Yu Y, Lu Y, Chen Y, Zhang H, Zhou G, Sun Z, Liu J, Sun D, Zhang G, Zou H, Zhong Y. Glutathione-Responsive Multilayer Coated Gold Nanoparticles for Targeted Gene Delivery. Journal of Biomedical Nanotechnology. 12: 503-15. PMID 27280248 DOI: 10.1166/Jbn.2016.2177  1
2016 Passalacqua KD, Charbonneau ME, Donato NJ, Showalter HD, Sun D, Wen B, He M, Sun H, O'Riordan MX, Wobus CE. Anti-infective activity of 2-cyano-3-acrylamide inhibitors with improved drug-like properties against two intracellular pathogens. Antimicrobial Agents and Chemotherapy. PMID 27139470 DOI: 10.1128/Aac.03021-15  0.8
2016 Sun L, Burnett J, Guo C, Xie Y, Pan J, Yang Z, Ran Y, Sun D. CPA4 is a promising diagnostic serum biomarker for pancreatic cancer. American Journal of Cancer Research. 6: 91-6. PMID 27073726  0.84
2016 Li Y, Sun D, Palmisano M, Zhou S. Slow drug delivery decreased total body clearance and altered bioavailability of immediate- and controlled-release oxycodone formulations. Pharmacology Research & Perspectives. 4: e00210. PMID 26977300 DOI: 10.1002/Prp2.210  0.68
2016 Ren Y, Wang R, Gao L, Li K, Zhou X, Guo H, Liu C, Han D, Tian J, Ye Q, Hu YT, Sun D, Yuan X, Zhang N. Sequential co-delivery of miR-21 inhibitor followed by burst release doxorubicin using NIR-responsive hollow gold nanoparticle to enhance anticancer efficacy. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26956593 DOI: 10.1016/J.Jconrel.2016.03.008  0.48
2016 Hsu EC, Kulp SK, Huang HL, Tu HJ, Chao MW, Tseng YC, Yang MC, Salunke SB, Sullivan NJ, Chen WC, Zhang J, Teng CM, Fu WM, Sun D, Wicha MS, et al. Integrin-linked kinase as a novel molecular switch of the IL-6-NF-κB signaling loop in breast cancer. Carcinogenesis. PMID 26905583 DOI: 10.1093/Carcin/Bgw020  0.8
2016 Borkin D, Pollock JW, Kempinska K, Purohit T, Li X, Wen B, Zhao T, Miao H, Shukla S, He M, Sun D, Cierpicki T, Grembecka J. Property focused structure-based optimization of small molecule inhibitors of the protein-protein interaction between menin and Mixed Lineage Leukemia (MLL). Journal of Medicinal Chemistry. PMID 26744767 DOI: 10.1021/Acs.Jmedchem.5B01305  0.88
2016 Yu F, Huang J, Yu Y, Lu Y, Chen Y, Zhang H, Zhou G, Sun Z, Liu J, Sun D, Zhang G, Zou H, Zhong Y. Glutathione-responsive multilayer coated gold nanoparticles for targeted gene delivery Journal of Biomedical Nanotechnology. 12: 503-515. DOI: 10.1166/jbn.2016.2177  0.48
2016 Chen H, Luan X, Stevers N, Sansanaphongpricha K, Burnett J, Paholak H, Sun D. Abstract 4912: Boosting immunotherapy via stealthy nanoparticle-mediated photothermal therapy Cancer Research. 76: 4912-4912. DOI: 10.1158/1538-7445.Am2016-4912  0.64
2016 Pollock J, Borkin D, Kempinska K, Purohit T, Li X, Wen B, Zhao T, Miao H, Shukla S, He M, Sun D, Cierpicki T, Grembecka J. Abstract 3898: Structure-based optimization of small molecule inhibitors of the protein-protein interaction between menin and mixed lineage leukemia (MLL) Cancer Research. 76: 3898-3898. DOI: 10.1158/1538-7445.Am2016-3898  0.88
2016 Reed R, Lo M, Lin C, Sun D. Abstract 3091: Development and optimization of a fluorescence polarization-based assay for the discovery of inhibitors of the RBBP4/7-Histone H3 interaction Cancer Research. 76: 3091-3091. DOI: 10.1158/1538-7445.Am2016-3091  0.44
2016 Gasparyan M, Burnett JP, Sun L, Sun D. Abstract 2509: Determining the functional and mechanistic role of homeobox transcription factor Meox1 in breast cancer and breast cancer stem cells Cancer Research. 76: 2509-2509. DOI: 10.1158/1538-7445.Am2016-2509  0.64
2016 Sansanaphongpricha K, Chen H, Sun K, Wen B, Sun D. Abstract 1331: Janus nanostructures for magnetic resonance imaging and enhanced photothermal therapy for cancer theranostics Cancer Research. 76: 1331-1331. DOI: 10.1158/1538-7445.Am2016-1331  0.56
2016 Bai L, Zhao Y, Liu L, Yang C, McEachern D, Stuckey J, Meagher J, Wen B, Sun D, Wang S. Abstract 1250: Antitumor activities of CD161, a structurally novel and orally bioavailable BET inhibitor, in leukemia and triple negative breast cancer cellsin vitroandin vivo Cancer Research. 76: 1250-1250. DOI: 10.1158/1538-7445.Am2016-1250  0.64
2015 Wu S, Yang Z, Ye R, An D, Li C, Wang Y, Wang Y, Huang Y, Liu H, Li F, He L, Sun D, Yu Y, Li Q, Huang P, et al. Novel variants in MLL confer to bladder cancer recurrence identified by whole-exome sequencing. Oncotarget. PMID 26625313 DOI: 10.18632/Oncotarget.6380  0.4
2015 Wu N, Wei J, Wang Y, Yan J, Qin Y, Tong D, Pang B, Sun D, Sun H, Yu Y, Sun W, Meng X, Zhang C, Bai J, Chen F, et al. Ribosomal L22-like1 (RPL22L1) Promotes Ovarian Cancer Metastasis by Inducing Epithelial-to-Mesenchymal Transition. Plos One. 10: e0143659. PMID 26618703 DOI: 10.1371/journal.pone.0143659  0.56
2015 Chen C, Zhang T, Zhang Q, Feng Z, Zhu C, Yu Y, Li K, Zhao M, Yang J, Liu J, Sun D. Three-Dimensional BC/PEDOT Composite Nanofibers with High Performance for Electrode-Cell Interface. Acs Applied Materials & Interfaces. PMID 26550840 DOI: 10.1021/Acsami.5B07273  0.52
2015 Burnett JP, Korkaya H, Ouzounova MD, Jiang H, Conley SJ, Newman BW, Sun L, Connarn JN, Chen CS, Zhang N, Wicha MS, Sun D. Trastuzumab resistance induces EMT to transform HER2(+) PTEN(-) to a triple negative breast cancer that requires unique treatment options. Scientific Reports. 5: 15821. PMID 26522776 DOI: 10.1038/Srep15821  0.8
2015 Yang S, Li C, Xie Y, Cui X, Li X, Wei J, Zhang Y, Yu Y, Wang Y, Zhang S, Zhang Q, Sun D. Detection of functional polymorphisms influencing the promoter activity of the SAA2 gene and their association with milk production traits in Chinese Holstein cows. Animal Genetics. PMID 26373797 DOI: 10.1111/age.12332  1
2015 Wang X, Ma P, Liu J, Zhang Q, Zhang Y, Ding X, Jiang L, Wang Y, Zhang Y, Sun D, Zhang S, Su G, Yu Y. Genome-wide association study in Chinese Holstein cows reveal two candidate genes for somatic cell score as an indicator for mastitis susceptibility. Bmc Genetics. 16: 111. PMID 26370837 DOI: 10.1186/s12863-015-0263-3  1
2015 Sun D, Lu J, Zhong Y, Yu Y, Wang Y, Zhang B, Chen Z. Sensitive electrochemical aptamer cytosensor for highly specific detection of cancer cells based on the hybrid nanoelectrocatalysts and enzyme for signal amplification. Biosensors & Bioelectronics. 75: 301-307. PMID 26332382 DOI: 10.1016/j.bios.2015.08.056  0.76
2015 Xiong X, Sun D, Chai H, Shan W, Yu Y, Pu L, Cheng F. MiR-145 functions as a tumor suppressor targeting NUAK1 in human intrahepatic cholangiocarcinoma. Biochemical and Biophysical Research Communications. 465: 262-9. PMID 26255969 DOI: 10.1016/j.bbrc.2015.08.013  1
2015 Sun D, Lu J, Chen Z, Yu Y, Mo M. A repeatable assembling and disassembling electrochemical aptamer cytosensor for ultrasensitive and highly selective detection of human liver cancer cells. Analytica Chimica Acta. 885: 166-73. PMID 26231902 DOI: 10.1016/j.aca.2015.05.027  0.76
2015 Hsu EC, Kulp SK, Huang HL, Tu HJ, Salunke SB, Sullivan NJ, Sun D, Wicha MS, Shapiro CL, Chen CS. Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6-Abundant Breast Cancer Cells by Regulating γ-Secretase-Mediated Notch1 Activation in Caveolae. Neoplasia (New York, N.Y.). 17: 497-508. PMID 26152358 DOI: 10.1016/J.Neo.2015.06.001  0.8
2015 Chen H, Ren X, Paholak HJ, Burnett J, Ni F, Fang X, Sun D. Facile Fabrication of Near-Infrared-Resonant and Magnetic Resonance Imaging-Capable Nanomediators for Photothermal Therapy. Acs Applied Materials & Interfaces. 7: 12814-23. PMID 26010660 DOI: 10.1021/Acsami.5B01991  0.64
2015 Friese CR, Mendelsohn-Victor K, Wen B, Sun D, Sutcliffe K, Yang JJ, Ronis DL, McCullagh MC. DEFENS - Drug Exposure Feedback and Education for Nurses' Safety: study protocol for a randomized controlled trial. Trials. 16: 171. PMID 25928792 DOI: 10.1186/S13063-015-0674-5  0.8
2015 Connarn JN, Zhang X, Babiskin A, Sun D. Metabolism of bupropion by carbonyl reductases in liver and intestine. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 1019-27. PMID 25904761 DOI: 10.1124/Dmd.115.063107  0.8
2015 Borkin D, He S, Miao H, Kempinska K, Pollock J, Chase J, Purohit T, Malik B, Zhao T, Wang J, Wen B, Zong H, Jones M, Danet-Desnoyers G, Guzman ML, ... ... Sun D, et al. Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo. Cancer Cell. 27: 589-602. PMID 25817203 DOI: 10.1016/J.Ccell.2015.02.016  0.8
2015 Peterson LF, Sun H, Liu Y, Potu H, Kandarpa M, Ermann M, Courtney SM, Young M, Showalter HD, Sun D, Jakubowiak A, Malek SN, Talpaz M, Donato NJ. Targeting deubiquitinase activity with a novel small-molecule inhibitor as therapy for B-cell malignancies. Blood. 125: 3588-97. PMID 25814533 DOI: 10.1182/Blood-2014-10-605584  0.88
2015 Wang Y, Liu Y, Liu Y, Zhou W, Wang H, Wan G, Sun D, Zhang N, Wang Y. A polymeric prodrug of cisplatin based on pullulan for the targeted therapy against hepatocellular carcinoma. International Journal of Pharmaceutics. 483: 89-100. PMID 25681730 DOI: 10.1016/J.Ijpharm.2015.02.027  0.8
2015 Dong T, Yan Y, Chai H, Chen S, Xiong X, Sun D, Yu Y, Deng L, Cheng F. Pyruvate kinase M2 affects liver cancer cell behavior through up-regulation of HIF-1α and Bcl-xL in culture. Biomedicine & Pharmacotherapy = BioméDecine & PharmacothéRapie. 69: 277-84. PMID 25661370 DOI: 10.1016/j.biopha.2014.12.010  0.72
2015 Wang Y, Yue D, Xiao M, Qi C, Chen Y, Sun D, Zhang N, Chen R. C1QBP negatively regulates the activation of oncoprotein YBX1 in the renal cell carcinoma as revealed by interactomics analysis. Journal of Proteome Research. 14: 804-13. PMID 25497084 DOI: 10.1021/Pr500847P  0.88
2015 Yu Y, Chen Z, Jian W, Sun D, Zhang B, Li X, Yao M. Ultrasensitive electrochemical detection of avian influenza A (H7N9) virus DNA based on isothermal exponential amplification coupled with hybridization chain reaction of DNAzyme nanowires. Biosensors & Bioelectronics. 64: 566-71. PMID 25310490 DOI: 10.1016/j.bios.2014.09.080  1
2015 Friese CR, McArdle C, Zhao T, Sun D, Spasojevic I, Polovich M, McCullagh MC. Antineoplastic drug exposure in an ambulatory setting: a pilot study. Cancer Nursing. 38: 111-7. PMID 24831047 DOI: 10.1097/Ncc.0000000000000143  0.8
2015 Paholak HJ, Stevers NO, Burnett JP, Chen H, McDermott SP, He M, Luther T, Clouthier SG, Wicha MS, Sun D. Abstract 4239: Epithelial-like breast cancer stem cells are preferentially sensitive to nanoparticle-mediated hyperthermia Cancer Research. 75: 4239-4239. DOI: 10.1158/1538-7445.Am2015-4239  0.88
2015 Burnett JP, Shah RB, Paholak HJ, McDermott SP, Tsume Y, Wicha MW, Sun D. Abstract 4076: Combination of docetaxel with sulforaphane synergistically inhibits triple negative breast cancer and cancer stem cells Cancer Research. 75: 4076-4076. DOI: 10.1158/1538-7445.Am2015-4076  0.52
2015 Chen H, Ren X, Paholak H, Burnett J, Ni F, Sun D. Abstract 3681: Facile fabrication of MRI-capable and NIR-resonant core-satellite nanomediators for photothermal therapy Cancer Research. 75: 3681-3681. DOI: 10.1158/1538-7445.Am2015-3681  0.64
2015 Reed RA, Lo M, Sun D. Abstract 106: Characterization of polycomb repressive complex 2 (PRC2) subunits retinoblastoma-binding protein 4 and 7 (RbBP4/7) in triple-negative breast cancer Cancer Research. 75: 106-106. DOI: 10.1158/1538-7445.Am2015-106  0.44
2014 Chen H, Burnett J, Zhang F, Zhang J, Paholak H, Sun D. Highly crystallized iron oxide nanoparticles as effective and biodegradable mediators for photothermal cancer therapy. Journal of Materials Chemistry. B. 2: 757-765. PMID 32261307 DOI: 10.1039/C3Tb21338B  0.64
2014 Kintzel PE, Zhao T, Wen B, Sun D. Stability of i.v. admixture containing metoclopramide, diphenhydramine hydrochloride, and dexamethasone sodium phosphate in 0.9% sodium chloride injection. American Journal of Health-System Pharmacy : Ajhp : Official Journal of the American Society of Health-System Pharmacists. 71: 2061-5. PMID 25404598 DOI: 10.2146/Ajhp130697  0.48
2014 Chen S, Shao C, Dong T, Chai H, Xiong X, Sun D, Zhang L, Yu Y, Wang P, Cheng F. Transplantation of ATP7B-transduced bone marrow mesenchymal stem cells decreases copper overload in rats. Plos One. 9: e111425. PMID 25375371 DOI: 10.1371/journal.pone.0111425  1
2014 Chen J, Jiang C, Levant B, Li X, Zhao T, Wen B, Luo R, Sun D, Wang S. Pramipexole derivatives as potent and selective dopamine D(3) receptor agonists with improved human microsomal stability. Chemmedchem. 9: 2653-60. PMID 25338762 DOI: 10.1002/Cmdc.201402398  0.8
2014 Liu Y, Wang Y, Zhang C, Zhou P, Liu Y, An T, Sun D, Zhang N, Wang Y. Core-shell nanoparticles based on pullulan and poly(β-amino) ester for hepatoma-targeted codelivery of gene and chemotherapy agent. Acs Applied Materials & Interfaces. 6: 18712-20. PMID 25289563 DOI: 10.1021/Am504203X  0.88
2014 Yu Y, Chen Z, Shi L, Yang F, Pan J, Zhang B, Sun D. Ultrasensitive electrochemical detection of microRNA based on an arched probe mediated isothermal exponential amplification. Analytical Chemistry. 86: 8200-5. PMID 25054588 DOI: 10.1021/ac501505a  1
2014 Sun D, Sun W, Yu Y, Li Z, Deng Z, Lin S. A new glutarimide derivative from marine sponge-derived Streptomyces anulatus S71. Natural Product Research. 28: 1602-6. PMID 24949797 DOI: 10.1080/14786419.2014.928877  1
2014 Chen H, Zou H, Paholak HJ, Ito M, Qian W, Che Y, Sun D. Thiol-reactive amphiphilic block copolymer for coating gold nanoparticles with neutral and functionable surfaces. Polymer Chemistry. 5: 2768-2773. PMID 24729795 DOI: 10.1039/C3Py01652H  0.64
2014 Zhang Y, Li Q, Ye S, Faruque MO, Yu Y, Sun D, Zhang S, Wang Y. New variants in the melanocortin 1 receptor gene (MC1R) in Asian cattle. Animal Genetics. 45: 609-10. PMID 24702190 DOI: 10.1111/age.12160  1
2014 Larsen MJ, Larsen SD, Fribley A, Grembecka J, Homan K, Mapp A, Haak A, Nikolovska-Coleska Z, Stuckey JA, Sun D, Sherman DH. The role of HTS in drug discovery at the University of Michigan. Combinatorial Chemistry & High Throughput Screening. 17: 210-30. PMID 24409957 DOI: 10.2174/1386207317666140109121546  0.8
2014 Connarn JN, Assimon VA, Reed RA, Tse E, Southworth DR, Zuiderweg ER, Gestwicki JE, Sun D. The molecular chaperone Hsp70 activates protein phosphatase 5 (PP5) by binding the tetratricopeptide repeat (TPR) domain. The Journal of Biological Chemistry. 289: 2908-17. PMID 24327656 DOI: 10.1074/Jbc.M113.519421  0.8
2014 Huang J, Zhang H, Yu Y, Chen Y, Wang D, Zhang G, Zhou G, Liu J, Sun Z, Sun D, Lu Y, Zhong Y. Biodegradable self-assembled nanoparticles of poly (D,L-lactide-co-glycolide)/hyaluronic acid block copolymers for target delivery of docetaxel to breast cancer. Biomaterials. 35: 550-66. PMID 24135268 DOI: 10.1016/J.Biomaterials.2013.09.089  1
2014 Zou P, Stern ST, Sun D. PLGA/liposome hybrid nanoparticles for short-chain ceramide delivery. Pharmaceutical Research. 31: 684-93. PMID 24065591 DOI: 10.1007/S11095-013-1190-5  0.6
2014 Abulwerdi F, Liao C, Liu M, Azmi AS, Aboukameel A, Mady AS, Gulappa T, Cierpicki T, Owens S, Zhang T, Sun D, Stuckey JA, Mohammad RM, Nikolovska-Coleska Z. A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo. Molecular Cancer Therapeutics. 13: 565-75. PMID 24019208 DOI: 10.1158/1535-7163.Mct-12-0767  0.8
2014 Pan J, Chen Z, Yao M, Li X, Li Y, Sun D, Yu Y. A two-electrode system-based electrochemiluminescence detection for microfluidic capillary electrophoresis and its application in pharmaceutical analysis. Luminescence : the Journal of Biological and Chemical Luminescence. 29: 427-32. PMID 23913856 DOI: 10.1002/bio.2565  1
2014 Gu M, Yu Y, Gunaherath GM, Gunatilaka AA, Li D, Sun D. Structure-activity relationship (SAR) of withanolides to inhibit Hsp90 for its activity in pancreatic cancer cells. Investigational New Drugs. 32: 68-74. PMID 23887853 DOI: 10.1007/S10637-013-9987-Y  1
2014 Chen H, Burnett J, Ren X, Ni F, Wei Y, Paholak H, Sun D. Abstract 5380: Near-infrared-resonant IONP/Au2S core/satellites hybrid nanocomposite for imaging-guided photothermal therapy Cancer Research. 74: 5380-5380. DOI: 10.1158/1538-7445.Am2014-5380  0.64
2014 Sun L, Burnett JP, Gasparyan M, Korkaya H, Jiang H, Liu Y, Connarn J, Wicha M, Sun D. Abstract 218: MEOX-1 as a novel cancer stem cell target for treatment of trastuzumab-resistant Her2+ breast cancers Cancer Research. 74: 218-218. DOI: 10.1158/1538-7445.Am2014-218  0.88
2014 Chen SL, Burnett J, Sun D, Xie Z, Wang X. Photoacoustic microscopy for quantitative evaluation of angiogenesis inhibitor Proceedings of Spie. 8943. DOI: 10.1117/12.2038054  0.64
2014 Ren X, Chen H, Yang V, Sun D. Iron oxide nanoparticle-based theranostics for cancer imaging and therapy Frontiers of Chemical Science and Engineering. 8: 253-264. DOI: 10.1007/S11705-014-1425-Y  0.56
2013 Lin L, Hutzen B, Lee HF, Peng Z, Wang W, Zhao C, Lin HJ, Sun D, Li PK, Li C, Korkaya H, Wicha MS, Lin J. Evaluation of STAT3 signaling in ALDH+ and ALDH+/CD44+/CD24- subpopulations of breast cancer cells. Plos One. 8: e82821. PMID 24376586 DOI: 10.1371/Journal.Pone.0082821  0.8
2013 Wang XS, Zhang Y, He YH, Ma PP, Fan LJ, Wang YC, Zhang YI, Sun DX, Zhang SL, Wang CD, Song JZ, Yu Y. Aberrant promoter methylation of the CD4 gene in peripheral blood cells of mastitic dairy cows. Genetics and Molecular Research : Gmr. 12: 6228-39. PMID 24338418 DOI: 10.4238/2013.December.4.10  0.76
2013 Li X, Srinivasan SR, Connarn J, Ahmad A, Young ZT, Kabza AM, Zuiderweg ER, Sun D, Gestwicki JE. Analogs of the Allosteric Heat Shock Protein 70 (Hsp70) Inhibitor, MKT-077, as Anti-Cancer Agents. Acs Medicinal Chemistry Letters. 4. PMID 24312699 DOI: 10.1021/Ml400204N  0.56
2013 Chen SL, Burnett J, Sun D, Wei X, Xie Z, Wang X. Photoacoustic microscopy: a potential new tool for evaluation of angiogenesis inhibitor. Biomedical Optics Express. 4: 2657-66. PMID 24298423 DOI: 10.1364/Boe.4.002657  0.64
2013 Jia X, Zhang F, Bai J, Gao L, Zhang X, Sun H, Sun D, Guan R, Sun W, Xu L, Yue Z, Yu Y, Fu S. Combinational analysis of linkage and exome sequencing identifies the causative mutation in a Chinese family with congenital cataract. Bmc Medical Genetics. 14: 107. PMID 24103489 DOI: 10.1186/1471-2350-14-107  1
2013 Zeller J, Turbiak AJ, Powelson IA, Lee S, Sun D, Showalter HD, Fearon ER. Investigation of 3-aryl-pyrimido[5,4-e][1,2,4]triazine-5,7-diones as small molecule antagonists of β-catenin/TCF transcription. Bioorganic & Medicinal Chemistry Letters. 23: 5814-20. PMID 24060489 DOI: 10.1016/J.Bmcl.2013.08.111  0.8
2013 Zou P, Chen H, Paholak HJ, Sun D. Noninvasive fluorescence resonance energy transfer imaging of in vivo premature drug release from polymeric nanoparticles. Molecular Pharmaceutics. 10: 4185-94. PMID 24033270 DOI: 10.1021/Mp4002393  0.6
2013 Yu L, Zhao Y, Quan C, Ji W, Zhu J, Huang Y, Guan R, Sun D, Jin Y, Meng X, Zhang C, Yu Y, Bai J, Sun W, Fu S. Gemcitabine eliminates double minute chromosomes from human ovarian cancer cells. Plos One. 8: e71988. PMID 23991020 DOI: 10.1371/journal.pone.0071988  0.56
2013 Chen H, Paholak H, Ito M, Sansanaphongpricha K, Qian W, Che Y, Sun D. 'Living' PEGylation on gold nanoparticles to optimize cancer cell uptake by controlling targeting ligand and charge densities. Nanotechnology. 24: 355101. PMID 23940104 DOI: 10.1088/0957-4484/24/35/355101  0.56
2013 Li Y, Zhang T, Li X, Zou P, Schwartz SJ, Sun D. Kinetics of sulforaphane in mice after consumption of sulforaphane-enriched broccoli sprout preparation. Molecular Nutrition & Food Research. 57: 2128-36. PMID 23929742 DOI: 10.1002/Mnfr.201300210  0.8
2013 Wang D, Huang J, Wang X, Yu Y, Zhang H, Chen Y, Liu J, Sun Z, Zou H, Sun D, Zhou G, Zhang G, Lu Y, Zhong Y. The eradication of breast cancer cells and stem cells by 8-hydroxyquinoline-loaded hyaluronan modified mesoporous silica nanoparticle-supported lipid bilayers containing docetaxel. Biomaterials. 34: 7662-73. PMID 23859657 DOI: 10.1016/J.Biomaterials.2013.06.042  1
2013 Zhang T, Li Y, Zou P, Yu JY, McEachern D, Wang S, Sun D. Physiologically based pharmacokinetic and pharmacodynamic modeling of an antagonist (SM-406/AT-406) of multiple inhibitor of apoptosis proteins (IAPs) in a mouse xenograft model of human breast cancer. Biopharmaceutics & Drug Disposition. 34: 348-59. PMID 23813446 DOI: 10.1002/Bdd.1850  0.8
2013 Zhao Y, Yu S, Sun W, Liu L, Lu J, McEachern D, Shargary S, Bernard D, Li X, Zhao T, Zou P, Sun D, Wang S. A potent small-molecule inhibitor of the MDM2-p53 interaction (MI-888) achieved complete and durable tumor regression in mice. Journal of Medicinal Chemistry. 56: 5553-61. PMID 23786219 DOI: 10.1021/Jm4005708  0.8
2013 Ding X, Zhang Z, Li X, Wang S, Wu X, Sun D, Yu Y, Liu J, Wang Y, Zhang Y, Zhang S, Zhang Y, Zhang Q. Accuracy of genomic prediction for milk production traits in the Chinese Holstein population using a reference population consisting of cows. Journal of Dairy Science. 96: 5315-23. PMID 23746588 DOI: 10.3168/jds.2012-6194  1
2013 Zhao Y, Liu L, Sun W, Lu J, McEachern D, Li X, Yu S, Bernard D, Ochsenbein P, Ferey V, Carry JC, Deschamps JR, Sun D, Wang S. Diastereomeric spirooxindoles as highly potent and efficacious MDM2 inhibitors. Journal of the American Chemical Society. 135: 7223-34. PMID 23641733 DOI: 10.1021/Ja3125417  0.8
2013 Zhou G, Lu Y, Zhang H, Chen Y, Yu Y, Gao J, Sun D, Zhang G, Zou H, Zhong Y. A novel pulsed drug-delivery system: polyelectrolyte layer-by-layer coating of chitosan-alginate microgels. International Journal of Nanomedicine. 8: 877-87. PMID 23486565 DOI: 10.2147/Ijn.S38144  1
2013 Miyata Y, Li X, Lee HF, Jinwal UK, Srinivasan SR, Seguin SP, Young ZT, Brodsky JL, Dickey CA, Sun D, Gestwicki JE. Synthesis and initial evaluation of YM-08, a blood-brain barrier permeable derivative of the heat shock protein 70 (Hsp70) inhibitor MKT-077, which reduces tau levels. Acs Chemical Neuroscience. 4: 930-9. PMID 23472668 DOI: 10.1021/Cn300210G  0.8
2013 Yestrepsky BD, Xu Y, Breen ME, Li X, Rajeswaran WG, Ryu JG, Sorenson RJ, Tsume Y, Wilson MW, Zhang W, Sun D, Sun H, Larsen SD. Novel inhibitors of bacterial virulence: development of 5,6-dihydrobenzo[h]quinazolin-4(3H)-ones for the inhibition of group A streptococcal streptokinase expression. Bioorganic & Medicinal Chemistry. 21: 1880-97. PMID 23433668 DOI: 10.1016/J.Bmc.2013.01.046  0.8
2013 Lin YW, Ren LL, Xiong H, Du W, Yu YN, Sun TT, Weng YR, Wang ZH, Wang JL, Wang YC, Cui Y, Sun DF, Han ZG, Shen N, Zou W, et al. Role of STAT3 and vitamin D receptor in EZH2-mediated invasion of human colorectal cancer. The Journal of Pathology. 230: 277-90. PMID 23424038 DOI: 10.1002/Path.4179  0.48
2013 Yang Q, Liu H, Qu L, Fu X, Yu Y, Yu G, Tian H, Yu Y, Sun D, Peng J, Bao F, Yuan C, Lu N, Li J, Zhang Y, et al. Investigation of 20 non-HLA (human leucocyte antigen) psoriasis susceptibility loci in Chinese patients with psoriatic arthritis and psoriasis vulgaris. The British Journal of Dermatology. 168: 1060-5. PMID 23252691 DOI: 10.1111/bjd.12142  1
2013 Burnett J, Korkaya H, Newman B, Conley S, Connarn J, Sun L, Lee H, Ouzounova M, Wicha M, Sun D. Abstract 913: Natural product sulforaphane selectively inhibits breast cancer stem cells in basal and trastuzumab resistant Her2+ breast cancer. Cancer Research. 73: 913-913. DOI: 10.1158/1538-7445.Am2013-913  0.84
2012 Zhang X, Qiao H, Zhao Y, Wang X, Sun H, Liu A, Xu L, Sun D, Jin Y, Yu Y, Meng X, Bai J, Chen F, Fu S. Association of single nucleotide polymorphisms in TCF2 with type 2 diabetes susceptibility in a Han Chinese population. Plos One. 7: e52938. PMID 23300827 DOI: 10.1371/journal.pone.0052938  1
2012 Zhang Y, Fan X, Sun D, Wang Y, Yu Y, Xie Y, Zhang S, Zhang Y. A novel method for rapid and reliable detection of complex vertebral malformation and bovine leukocyte adhesion deficiency in Holstein cattle. Journal of Animal Science and Biotechnology. 3: 24. PMID 22958243 DOI: 10.1186/2049-1891-3-24  1
2012 He Y, Yu Y, Zhang Y, Song J, Mitra A, Zhang Y, Wang Y, Sun D, Zhang S. Genome-wide bovine H3K27me3 modifications and the regulatory effects on genes expressions in peripheral blood lymphocytes. Plos One. 7: e39094. PMID 22761725 DOI: 10.1371/journal.pone.0039094  0.76
2012 Newman B, Liu Y, Lee HF, Sun D, Wang Y. HSP90 inhibitor 17-AAG selectively eradicates lymphoma stem cells. Cancer Research. 72: 4551-61. PMID 22751135 DOI: 10.1158/0008-5472.Can-11-3600  0.88
2012 Burnett J, Newman B, Sun D. Targeting cancer stem cells with natural products. Current Drug Targets. 13: 1054-64. PMID 22594473 DOI: 10.2174/138945012802009062  0.64
2012 Zou P, Zheng N, Yang Y, Yu LX, Sun D. Prediction of volume of distribution at steady state in humans: comparison of different approaches. Expert Opinion On Drug Metabolism & Toxicology. 8: 855-72. PMID 22591253 DOI: 10.1517/17425255.2012.682569  0.8
2012 Zou P, Zheng N, Yu Y, Yu S, Sun W, McEachem D, Yang Y, Yu LX, Wang S, Sun D. Preclinical pharmacokinetics of MI-219, a novel human double minute 2 (HDM2) inhibitor and prediction of human pharmacokinetics. Journal of Pharmacy & Pharmaceutical Sciences : a Publication of the Canadian Society For Pharmaceutical Sciences, Sociã©Tã© Canadienne Des Sciences Pharmaceutiques. 15: 265-80. PMID 22579006 DOI: 10.18433/J34S4N  0.8
2012 Yu S, Zhang G, Zhang W, Luo H, Qiu L, Liu Q, Sun D, Wang PG, Wang F. Synthesis and biological activities of a 3'-azido analogue of Doxorubicin against drug-resistant cancer cells. International Journal of Molecular Sciences. 13: 3671-84. PMID 22489175 DOI: 10.3390/Ijms13033671  0.64
2012 Li Y, Karagöz GE, Seo YH, Zhang T, Jiang Y, Yu Y, Duarte AM, Schwartz SJ, Boelens R, Carroll K, Rüdiger SG, Sun D. Sulforaphane inhibits pancreatic cancer through disrupting Hsp90-p50(Cdc37) complex and direct interactions with amino acids residues of Hsp90. The Journal of Nutritional Biochemistry. 23: 1617-26. PMID 22444872 DOI: 10.1016/J.Jnutbio.2011.11.004  0.8
2012 Zou P, Yu Y, Zheng N, Yang Y, Paholak HJ, Yu LX, Sun D. Applications of human pharmacokinetic prediction in first-in-human dose estimation. The Aaps Journal. 14: 262-81. PMID 22407287 DOI: 10.1208/S12248-012-9332-Y  0.8
2012 Zhu J, Lee H, Korkaya H, Liu S, McDemott S, Wicha MS, Sun D. Abstract LB-100: Computational assessment of oncogenic pathways modulated by vorinostat in breast cancer stem cells Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-100  0.84
2012 Chen H, Zou P, Paholak H, Sun D. Abstract 2898: Intracellular dissociation of polymer coating from nanoparticles Cancer Research. 72: 2898-2898. DOI: 10.1158/1538-7445.Am2012-2898  0.6
2012 Sun W, Sun D. Coupled modelling of hydro-mechanical behaviour of unsaturated compacted expansive soils International Journal For Numerical and Analytical Methods in Geomechanics. 36: 1002-1022. DOI: 10.1002/nag.1036  0.36
2011 Li Y, Zhang T, Schwartz SJ, Sun D. Sulforaphane potentiates the efficacy of 17-allylamino 17-demethoxygeldanamycin against pancreatic cancer through enhanced abrogation of Hsp90 chaperone function. Nutrition and Cancer. 63: 1151-9. PMID 21875325 DOI: 10.1080/01635581.2011.596645  0.8
2011 Yu Y, Zick S, Li X, Zou P, Wright B, Sun D. Examination of the pharmacokinetics of active ingredients of ginger in humans. The Aaps Journal. 13: 417-26. PMID 21638149 DOI: 10.1208/S12248-011-9286-5  1
2011 Sun H, Liu L, Lu J, Bai L, Li X, Nikolovska-Coleska Z, McEachern D, Yang CY, Qiu S, Yi H, Sun D, Wang S. Potent bivalent Smac mimetics: effect of the linker on binding to inhibitor of apoptosis proteins (IAPs) and anticancer activity. Journal of Medicinal Chemistry. 54: 3306-18. PMID 21462933 DOI: 10.1021/Jm101651B  0.8
2011 Cai Q, Sun H, Peng Y, Lu J, Nikolovska-Coleska Z, McEachern D, Liu L, Qiu S, Yang CY, Miller R, Yi H, Zhang T, Sun D, Kang S, Guo M, et al. A potent and orally active antagonist (SM-406/AT-406) of multiple inhibitor of apoptosis proteins (IAPs) in clinical development for cancer treatment. Journal of Medicinal Chemistry. 54: 2714-26. PMID 21443232 DOI: 10.1021/Jm101505D  0.8
2011 Li Y, Wicha MS, Schwartz SJ, Sun D. Implications of cancer stem cell theory for cancer chemoprevention by natural dietary compounds. The Journal of Nutritional Biochemistry. 22: 799-806. PMID 21295962 DOI: 10.1016/J.Jnutbio.2010.11.001  0.8
2011 Zheng N, Zou P, Wang S, Sun D. In vitro metabolism of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin in human liver microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 627-35. PMID 21177985 DOI: 10.1124/Dmd.110.036418  0.8
2011 Wang S, Sun W, Yu S, Zhao Y, Kumar S, McEachern D, Liu L, Bernard D, Sun D, Zou P, Li X, Yi H, Stuckey J, Long J, Malek S, et al. Abstract LB-204: Highly potent and optimized small-molecule inhibitors of MDM2 achieve complete tumor regression in animal models of solid tumors and leukemia. Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-204  0.64
2011 Newman BW, Zhang Q, Lu Y, Zhai J, Ding Y, Ma W, Fan H, Long J, Zhang H, Wang M, Chen Y, Sun D. Abstract 3350: Inhibition of breast cancer and cancer stem cells via a novel micheliolide analogue CY-9 Cancer Research. 71: 3350-3350. DOI: 10.1158/1538-7445.Am2011-3350  0.88
2011 Sun F, Sun D. Evaluation on agricultural relative efficiency in different areas of China Proceedings of 2011 International Conference On Electronic and Mechanical Engineering and Information Technology, Emeit 2011. 4: 1986-1990. DOI: 10.1109/EMEIT.2011.6023491  0.4
2011 Dai F, Sun D. Three 3D lanthanide-organic frameworks based on novel flexible multicarboxylates: From ssa to rtl topologies Crystal Growth and Design. 11: 5670-5675. DOI: 10.1021/Cg201210P  0.32
2010 Yu Y, Sun D. Superparamagnetic iron oxide nanoparticle 'theranostics' for multimodality tumor imaging, gene delivery, targeted drug and prodrug delivery. Expert Review of Clinical Pharmacology. 3: 117-30. PMID 22111537 DOI: 10.1586/ecp.09.39  1
2010 Sun D. Nanotheranostics: integration of imaging and targeted drug delivery. Molecular Pharmaceutics. 7: 1879. PMID 21128687 DOI: 10.1021/Mp1003652  0.8
2010 Zou P, Yu Y, Wang YA, Zhong Y, Welton A, Galbán C, Wang S, Sun D. Superparamagnetic iron oxide nanotheranostics for targeted cancer cell imaging and pH-dependent intracellular drug release. Molecular Pharmaceutics. 7: 1974-84. PMID 20845930 DOI: 10.1021/Mp100273T  0.8
2010 Zou P, Povoski SP, Hall NC, Carlton MM, Hinkle GH, Xu RX, Mojzisik CM, Johnson MA, Knopp MV, Martin EW, Sun D. 124I-HuCC49deltaCH2 for TAG-72 antigen-directed positron emission tomography (PET) imaging of LS174T colon adenocarcinoma tumor implants in xenograft mice: preliminary results. World Journal of Surgical Oncology. 8: 65. PMID 20691066 DOI: 10.1186/1477-7819-8-65  0.8
2010 Zhang T, Li Y, Zhu Z, Gu M, Newman B, Sun D. MEK inhibition potentiates the activity of Hsp90 inhibitor 17-AAG against pancreatic cancer cells. Molecular Pharmaceutics. 7: 1576-84. PMID 20669973 DOI: 10.1021/Mp900321A  0.68
2010 Liu Q, Zhang H, Zhou G, Xie S, Zou H, Yu Y, Li G, Sun D, Zhang G, Lu Y, Zhong Y. In vitro and in vivo study of thymosin alpha1 biodegradable in situ forming poly(lactide-co-glycolide) implants. International Journal of Pharmaceutics. 397: 122-9. PMID 20650309 DOI: 10.1016/J.Ijpharm.2010.07.015  1
2010 Zhu Z, Xu X, Yu Y, Graham M, Prince ME, Carey TE, Sun D. Silencing heat shock protein 27 decreases metastatic behavior of human head and neck squamous cell cancer cells in vitro. Molecular Pharmaceutics. 7: 1283-90. PMID 20540527 DOI: 10.1021/Mp100073S  0.8
2010 Jiang Y, Bernard D, Yu Y, Xie Y, Zhang T, Li Y, Burnett JP, Fu X, Wang S, Sun D. Split Renilla luciferase protein fragment-assisted complementation (SRL-PFAC) to characterize Hsp90-Cdc37 complex and identify critical residues in protein/protein interactions. The Journal of Biological Chemistry. 285: 21023-36. PMID 20413594 DOI: 10.1074/Jbc.M110.103390  0.8
2010 Li Y, Zhang T, Korkaya H, Liu S, Lee HF, Newman B, Yu Y, Clouthier SG, Schwartz SJ, Wicha MS, Sun D. Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 2580-90. PMID 20388854 DOI: 10.1158/1078-0432.Ccr-09-2937  0.8
2010 Yu Y, Fang L, Sun D. Biodistribution of HuCC49DeltaCH2-beta-galactosidase in colorectal cancer xenograft model. International Journal of Pharmaceutics. 386: 208-15. PMID 19944136 DOI: 10.1016/J.Ijpharm.2009.11.020  1
2010 Yu Y, Hamza A, Zhang T, Gu M, Zou P, Newman B, Li Y, Gunatilaka AA, Zhan CG, Sun D. Withaferin A targets heat shock protein 90 in pancreatic cancer cells. Biochemical Pharmacology. 79: 542-51. PMID 19769945 DOI: 10.1016/J.Bcp.2009.09.017  1
2010 Kakarala M, Sun D, Wicha MS. Abstract CN08-02: Implications of the cancer stem cell hypothesis for breast cancer prevention Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-10-Cn08-02  0.84
2010 Li Y, Zhang T, Korkaya H, Liu S, Lee H, Newman B, Yu Y, Clouthier S, Schwartz S, Wicha M, Sun D. Abstract 4271: Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells Cancer Research. 70: 4271-4271. DOI: 10.1158/1538-7445.Am10-4271  1
2010 Zhu Z, Xu X, Yu Y, Graham M, Liu G, Prince M, Carey T, Sun D. Abstract 3392: Heat shock protein 27 increases metastasis of human head and neck squamous cancer cellsin vitro Cancer Research. 70: 3392-3392. DOI: 10.1158/1538-7445.Am10-3392  1
2010 Jiang Y, Bernard D, Yu Y, Zhang T, Li Y, Fu X, Wang S, Sun D. Abstract 2672: Characterization of Hsp90/Cdc37 interaction and their critical residues using luciferase fragment complementation imaging Cancer Research. 70: 2672-2672. DOI: 10.1158/1538-7445.Am10-2672  1
2010 Sun D, Sun B. Rapid prediction of earthquake damage to buildings based on fuzzy analysis Proceedings - 2010 7th International Conference On Fuzzy Systems and Knowledge Discovery, Fskd 2010. 3: 1332-1335. DOI: 10.1109/FSKD.2010.5569101  0.52
2009 Zhang T, Li Y, Yu Y, Zou P, Jiang Y, Sun D. Characterization of celastrol to inhibit hsp90 and cdc37 interaction. The Journal of Biological Chemistry. 284: 35381-9. PMID 19858214 DOI: 10.1074/Jbc.M109.051532  1
2009 Shin HC, Kim HR, Cho HJ, Yi H, Cho SM, Lee DG, Abd El-Aty AM, Kim JS, Sun D, Amidon GL. Comparative gene expression of intestinal metabolizing enzymes. Biopharmaceutics & Drug Disposition. 30: 411-21. PMID 19746353 DOI: 10.1002/Bdd.675  0.64
2009 Zou P, Xu S, Povoski SP, Wang A, Johnson MA, Martin EW, Subramaniam V, Xu R, Sun D. Near-infrared fluorescence labeled anti-TAG-72 monoclonal antibodies for tumor imaging in colorectal cancer xenograft mice. Molecular Pharmaceutics. 6: 428-40. PMID 19718796 DOI: 10.1021/Mp9000052  0.6
2009 Xu RX, Huang J, Xu JS, Sun D, Hinkle GH, Martin EW, Povoski SP. Fabrication of indocyanine green encapsulated biodegradable microbubbles for structural and functional imaging of cancer. Journal of Biomedical Optics. 14: 034020. PMID 19566313 DOI: 10.1117/1.3147424  0.8
2009 Li Y, Zhang T, Jiang Y, Lee HF, Schwartz SJ, Sun D. (-)-Epigallocatechin-3-gallate inhibits Hsp90 function by impairing Hsp90 association with cochaperones in pancreatic cancer cell line Mia Paca-2. Molecular Pharmaceutics. 6: 1152-9. PMID 19438225 DOI: 10.1021/Mp900037P  0.8
2009 Li Y, Zhang T, Schwartz SJ, Sun D. New developments in Hsp90 inhibitors as anti-cancer therapeutics: mechanisms, clinical perspective and more potential. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 12: 17-27. PMID 19179103 DOI: 10.1016/J.Drup.2008.12.002  0.8
2008 Shen J, Woodward R, Kedenburg JP, Liu X, Chen M, Fang L, Sun D, Wang PG. Histone deacetylase inhibitors through click chemistry. Journal of Medicinal Chemistry. 51: 7417-27. PMID 19007204 DOI: 10.1021/Jm8005355  0.92
2008 Polli JE, Abrahamsson BS, Yu LX, Amidon GL, Baldoni JM, Cook JA, Fackler P, Hartauer K, Johnston G, Krill SL, Lipper RA, Malick WA, Shah VP, Sun D, Winkle HN, et al. Summary workshop report: bioequivalence, biopharmaceutics classification system, and beyond. The Aaps Journal. 10: 373-9. PMID 18679807 DOI: 10.1208/S12248-008-9040-9  0.8
2008 Wang B, Povoski SP, Cao X, Sun D, Xu RX. Dynamic schema for near infrared detection of pressure-induced changes in solid tumors. Applied Optics. 47: 3053-63. PMID 18516127 DOI: 10.1364/Ao.47.003053  0.56
2008 Fang L, Sun D. Predictive physiologically based pharmacokinetic model for antibody-directed enzyme prodrug therapy. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 1153-65. PMID 18356268 DOI: 10.1124/Dmd.107.019182  0.92
2008 Cao X, Bloomston M, Zhang T, Frankel WL, Jia G, Wang B, Hall NC, Koch RM, Cheng H, Knopp MV, Sun D. Synergistic antipancreatic tumor effect by simultaneously targeting hypoxic cancer cells with HSP90 inhibitor and glycolysis inhibitor. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 1831-9. PMID 18347186 DOI: 10.1158/1078-0432.Ccr-07-1607  0.8
2008 Cao X, Jia G, Zhang T, Yang M, Wang B, Wassenaar PA, Cheng H, Knopp MV, Sun D. Non-invasive MRI tumor imaging and synergistic anticancer effect of HSP90 inhibitor and glycolysis inhibitor in RIP1-Tag2 transgenic pancreatic tumor model. Cancer Chemotherapy and Pharmacology. 62: 985-94. PMID 18253734 DOI: 10.1007/S00280-008-0688-8  0.8
2008 Yin D, Lu Y, Zhang H, Zhang G, Zou H, Sun D, Zhong Y. Preparation of glucagon-like peptide-1 loaded PLGA microspheres: characterizations, release studies and bioactivities in vitro/in vivo. Chemical & Pharmaceutical Bulletin. 56: 156-61. PMID 18239299 DOI: 10.1248/Cpb.56.156  0.88
2008 Zhang T, Hamza A, Cao X, Wang B, Yu S, Zhan CG, Sun D. A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells. Molecular Cancer Therapeutics. 7: 162-70. PMID 18202019 DOI: 10.1158/1535-7163.Mct-07-0484  0.56
2008 Zhang H, Lu Y, Zhang G, Gao S, Sun D, Zhong Y. Bupivacaine-loaded biodegradable poly(lactic-co-glycolic) acid microspheres I. Optimization of the drug incorporation into the polymer matrix and modelling of drug release. International Journal of Pharmaceutics. 351: 244-9. PMID 18024022 DOI: 10.1016/J.Ijpharm.2007.10.004  0.88
2008 Cui H, Shen J, Lu D, Zhang T, Zhang W, Sun D, Wang PG. 4-Aryl-1,3,2-oxathiazolylium-5-olate: a novel GST inhibitor to release JNK and activate c-Jun for cancer therapy. Cancer Chemotherapy and Pharmacology. 62: 509-15. PMID 18008069 DOI: 10.1007/S00280-007-0632-3  0.6
2008 Sun D, Sun Z. Electrochemical determination of Pb2+ using a carbon nanotube/Nafion composite film-modified electrode Journal of Applied Electrochemistry. 38: 1223-1227. DOI: 10.1007/s10800-008-9542-2  0.56
2007 Sun D, Bloomston M, Hinkle G, Al-Saif OH, Hall NC, Povoski SP, Arnold MW, Martin EW. Radioimmunoguided surgery (RIGS), PET/CT image-guided surgery, and fluorescence image-guided surgery: past, present, and future. Journal of Surgical Oncology. 96: 297-308. PMID 17726663 DOI: 10.1002/Jso.20869  0.4
2007 Kim HR, Park SW, Cho HJ, Chae KA, Sung JM, Kim JS, Landowski CP, Sun D, Abd El-Aty AM, Amidon GL, Shin HC. Comparative gene expression profiles of intestinal transporters in mice, rats and humans. Pharmacological Research. 56: 224-36. PMID 17681807 DOI: 10.1016/J.Phrs.2007.06.005  0.8
2007 Lu Y, Zhang G, Sun D, Zhong Y. Preparation and evaluation of biodegradable flubiprofen gelatin micro-spheres for intra-articular administration. Journal of Microencapsulation. 24: 515-24. PMID 17654172 DOI: 10.1080/02652040701433479  0.76
2007 Battisti RF, Zhong Y, Fang L, Gibbs S, Shen J, Nadas J, Zhang G, Sun D. Modifying the sugar moieties of daunorubicin overcomes P-gp-mediated multidrug resistance. Molecular Pharmaceutics. 4: 140-53. PMID 17274671 DOI: 10.1021/Mp060075V  0.8
2007 Fang L, Holford NH, Hinkle G, Cao X, Xiao JJ, Bloomston M, Gibbs S, Saif OH, Dalton JT, Chan KK, Schlom J, Martin EW, Sun D. Population pharmacokinetics of humanized monoclonal antibody HuCC49deltaCH2 and murine antibody CC49 in colorectal cancer patients. Journal of Clinical Pharmacology. 47: 227-37. PMID 17244774 DOI: 10.1177/0091270006293758  0.92
2007 Cao X, Fang L, Gibbs S, Huang Y, Dai Z, Wen P, Zheng X, Sadee W, Sun D. Glucose uptake inhibitor sensitizes cancer cells to daunorubicin and overcomes drug resistance in hypoxia. Cancer Chemotherapy and Pharmacology. 59: 495-505. PMID 16906425 DOI: 10.1007/S00280-006-0291-9  0.8
2006 Nadas J, Sun D. Anthracyclines as effective anticancer drugs. Expert Opinion On Drug Discovery. 1: 549-68. PMID 23506066 DOI: 10.1517/17460441.1.6.549  0.8
2006 Fang L, Battisti RF, Cheng H, Reigan P, Xin Y, Shen J, Ross D, Chan KK, Martin EW, Wang PG, Sun D. Enzyme specific activation of benzoquinone ansamycin prodrugs using HuCC49DeltaCH2-beta-galactosidase conjugates. Journal of Medicinal Chemistry. 49: 6290-7. PMID 17034135 DOI: 10.1021/Jm060647F  0.92
2006 Cao X, Gibbs ST, Fang L, Miller HA, Landowski CP, Shin HC, Lennernas H, Zhong Y, Amidon GL, Yu LX, Sun D. Why is it challenging to predict intestinal drug absorption and oral bioavailability in human using rat model. Pharmaceutical Research. 23: 1675-86. PMID 16841194 DOI: 10.1007/S11095-006-9041-2  0.8
2006 Zhang G, Fang L, Zhu L, Zhong Y, Wang PG, Sun D. Syntheses and biological activities of 3'-azido disaccharide analogues of daunorubicin against drug-resistant leukemia. Journal of Medicinal Chemistry. 49: 1792-9. PMID 16509594 DOI: 10.1021/Jm050916M  0.92
2006 Fang L, Zhang G, Li C, Zheng X, Zhu L, Xiao JJ, Szakacs G, Nadas J, Chan KK, Wang PG, Sun D. Discovery of a daunorubicin analogue that exhibits potent antitumor activity and overcomes P-gp-mediated drug resistance. Journal of Medicinal Chemistry. 49: 932-41. PMID 16451059 DOI: 10.1021/Jm050800Q  0.8
2006 Zhang G, Fang L, Zhu L, Sun D, Wang PG. Syntheses and biological activity of bisdaunorubicins. Bioorganic & Medicinal Chemistry. 14: 426-34. PMID 16182536 DOI: 10.1016/J.Bmc.2005.08.014  0.92
2006 Sun D, Sun X. Estimation of multivariate normal covariance and precision matrices in a star-shape model with missing data Journal of Multivariate Analysis. 97: 698-719. DOI: 10.1016/J.Jmva.2005.09.006  0.56
2005 Zhang G, Fang L, Zhu L, Aimiuwu JE, Shen J, Cheng H, Muller MT, Lee GE, Sun D, Wang PG. Syntheses and biological activities of disaccharide daunorubicins. Journal of Medicinal Chemistry. 48: 5269-78. PMID 16078845 DOI: 10.1021/Jm050144U  0.92
2005 Zhu L, Cao X, Chen W, Zhang G, Sun D, Wang PG. Syntheses and biological activities of daunorubicin analogs with uncommon sugars. Bioorganic & Medicinal Chemistry. 13: 6381-7. PMID 16055335 DOI: 10.1016/J.Bmc.2005.06.053  0.64
2005 Cao X, Yu LX, Barbaciru C, Landowski CP, Shin HC, Gibbs S, Miller HA, Amidon GL, Sun D. Permeability dominates in vivo intestinal absorption of P-gp substrate with high solubility and high permeability. Molecular Pharmaceutics. 2: 329-40. PMID 16053336 DOI: 10.1021/Mp0499104  0.8
2005 Zhang G, Shen J, Cheng H, Zhu L, Fang L, Luo S, Muller MT, Lee GE, Wei L, Du Y, Sun D, Wang PG. Syntheses and biological activities of rebeccamycin analogues with uncommon sugars. Journal of Medicinal Chemistry. 48: 2600-11. PMID 15801850 DOI: 10.1021/Jm0493764  0.92
2005 Xiao J, Horst S, Hinkle G, Cao X, Kocak E, Fang J, Young D, Khazaeli M, Agnese D, Sun D, Martin E. Pharmacokinetics and clinical evaluation of 125I-radiolabeled humanized CC49 monoclonal antibody (HuCC49deltaC(H)2) in recurrent and metastatic colorectal cancer patients. Cancer Biotherapy & Radiopharmaceuticals. 20: 16-26. PMID 15778575 DOI: 10.1089/Cbr.2005.20.16  0.52
2005 Cheng H, Cao X, Xian M, Fang L, Cai TB, Ji JJ, Tunac JB, Sun D, Wang PG. Synthesis and enzyme-specific activation of carbohydrate-geldanamycin conjugates with potent anticancer activity. Journal of Medicinal Chemistry. 48: 645-52. PMID 15658879 DOI: 10.1021/Jm049693A  0.8
2005 Sun D, Sun X. Estimation of the multivariate normal precision and covariance matrices in a star-shape model Annals of the Institute of Statistical Mathematics. 57: 455-484. DOI: 10.1007/Bf02509235  0.56
2004 Landowski CP, Anderle P, Sun D, Sadee W, Amidon GL. Transporter and ion channel gene expression after Caco-2 cell differentiation using 2 different microarray technologies. The Aaps Journal. 6: e21. PMID 15760106 DOI: 10.1208/Aapsj060321  0.8
2004 Sun D, Song B. Cytocompatibility of collagen membranes with bladder transitional cells of rabbit in vitro Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi = Zhongguo Xiufu Chongjian Waike Zazhi = Chinese Journal of Reparative and Reconstructive Surgery. 18: 217-219. PMID 15211840  0.36
2004 Sun D, Yu LX, Hussain MA, Wall DA, Smith RL, Amidon GL. In vitro testing of drug absorption for drug 'developability' assessment: forming an interface between in vitro preclinical data and clinical outcome. Current Opinion in Drug Discovery & Development. 7: 75-85. PMID 14982151  0.6
2004 Sun Z, Sun D. Optical constants and dispersion of Ag-MgF2 nanoparticle composite films Chinese Optics Letters. 2: 243-245.  0.56
2003 Shin HC, Landowski CP, Sun D, Vig BS, Kim I, Mittal S, Lane M, Rosania G, Drach JC, Amidon GL. Functional expression and characterization of a sodium-dependent nucleoside transporter hCNT2 cloned from human duodenum. Biochemical and Biophysical Research Communications. 307: 696-703. PMID 12893280 DOI: 10.1016/S0006-291X(03)01259-2  0.8
2003 Walters CL, Wang BC, Godfrey M, Sun D, Funk CD, Blendy JA. Augmented responses to morphine and cocaine in mice with a 12-lipoxygenase gene disruption. Psychopharmacology. 170: 124-31. PMID 12845410 DOI: 10.1007/S00213-003-1526-7  0.8
2003 Qi X, Liu RR, Sun D, Ackermann C, Hou H. Convolution method to predict drug concentration profiles of 2,3,5,6-tetramethylpyrazine following transdermal application. International Journal of Pharmaceutics. 259: 39-45. PMID 12787634 DOI: 10.1016/S0378-5173(03)00184-4  0.56
2003 Landowski CP, Sun D, Foster DR, Menon SS, Barnett JL, Welage LS, Ramachandran C, Amidon GL. Gene expression in the human intestine and correlation with oral valacyclovir pharmacokinetic parameters. The Journal of Pharmacology and Experimental Therapeutics. 306: 778-86. PMID 12750437 DOI: 10.1124/Jpet.103.051011  0.8
2003 Qi X, Ackermann C, Sun D, Sheng M, Hou H. Physicochemical characterization and percutaneous delivery of 2,3,5,6-tetramethylpyrazine. International Journal of Pharmaceutics. 253: 177-83. PMID 12593948 DOI: 10.1016/S0378-5173(03)00002-4  0.56
2002 Qi X, Ackermann C, Sun D, Liu R, Sheng M, Hou H. The prediction of plasma and brain levels of 2,3,5,6-tetramethylpyrazine following transdermal application. Aaps Pharmsci. 4: E46. PMID 12646016 DOI: 10.1208/Ps040446  0.56
2002 Sun D, Lennernas H, Welage LS, Barnett JL, Landowski CP, Foster D, Fleisher D, Lee KD, Amidon GL. Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs. Pharmaceutical Research. 19: 1400-16. PMID 12425456 DOI: 10.1023/A:1020483911355  0.8
2001 Sun D, Landowski CP, Chu X, Wallsten R, Komorowski TE, Fleisher D, Amidon GL. Drug inhibition of Gly-Sar uptake and hPepT1 localization using hPepT1-GFP fusion protein. Aaps Pharmsci. 3: E2. PMID 11741253 DOI: 10.1208/Ps030102  0.8
1999 Bleich D, Chen S, Zipser B, Sun D, Funk CD, Nadler JL. Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice Journal of Clinical Investigation. 103: 1431-1436. PMID 10330425 DOI: 10.1172/Jci5241  0.8
1999 Johnson EN, Sun D, Chen XS, Funk CD. Lipoxygenase gene disruption studies. Status and applications. Advances in Experimental Medicine and Biology. 447: 63-73. PMID 10086183 DOI: 10.1007/978-1-4615-4861-4_6  0.8
1996 Sun H, Sun D. Environmental design technology: discovering new color skills Journal of Healthcare Design : Proceedings From the ... Symposium On Healthcare Design. Symposium On Healthcare Design. 8: 121-125. PMID 10160304  0.52
1996 Sun D, Funk CD. Disruption of 12/15-Lipoxygenase Expression in Peritoneal Macrophages ENHANCED UTILIZATION OF THE 5-LIPOXYGENASE PATHWAY AND DIMINISHED OXIDATION OF LOW DENSITY LIPOPROTEIN Journal of Biological Chemistry. 271: 24055-24062. DOI: 10.1074/Jbc.271.39.24055  0.36
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