John C. Lukesh, Ph.D. - Publications

Affiliations: 
2017- Department of Chemistry Wake Forest University, Winston-Salem, NC, United States 
Area:
Medicinal Chemistry, Chemical Biology
Website:
https://lukeshjc.sites.wfu.edu

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hankins RA, Suarez SI, Kalk MA, Green NM, Harty MN, Lukesh JC. An Innovative Hydrogen Peroxide-Sensing Scaffold and Insight Towards its Potential as an ROS-Activated Persulfide Donor. Angewandte Chemie. DOI: 10.1002/Ange.202010530  0.387
2019 Suarez SI, Warner CC, Brown-Harding H, Thooft AM, VanVeller B, Lukesh JC. Highly selective staining and quantification of intracellular lipid droplets with a compact push-pull fluorophore based on benzothiadiazole. Organic & Biomolecular Chemistry. PMID 31850447 DOI: 10.1039/C9Ob02486G  0.611
2019 Suarez SI, Ambrose R, Kalk MA, Lukesh JC. Selenosulfides Tethered to Gem-Dimethyl Esters: A Robust and Highly Versatile Framework for H₂S Probe Development. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31576582 DOI: 10.1002/Chem.201904133  0.31
2018 Windsor IW, Palte MJ, Lukesh JC, Gold B, Forest KT, Raines RT. Sub-picomolar Inhibition of HIV-1 Protease with a Boronic Acid. Journal of the American Chemical Society. PMID 30346745 DOI: 10.1021/Jacs.8B07366  0.616
2017 Lukesh JC, Carney DW, Dong H, Cross RM, Shukla V, Duncan KK, Yang S, Brody DM, Brütsch MM, Radakovic A, Boger DL. Vinblastine 20' Amides: Synthetic Analogues That Maintain or Improve Potency and Simultaneously Overcome Pgp-Derived Efflux and Resistance. Journal of Medicinal Chemistry. PMID 28857558 DOI: 10.1021/acs.jmedchem.7b00958  0.351
2017 Yang S, Sankar K, Skepper CK, Barker TJ, Lukesh JC, Brody DM, Brütsch MM, Boger DL. Total synthesis of a key series of vinblastines modified at C4 that define the importance and surprising trends in activity. Chemical Science. 8: 1560-1569. PMID 28194270 DOI: 10.1039/C6Sc04146A  0.488
2016 Carney DW, Lukesh JC, Brody DM, Brütsch MM, Boger DL. Ultrapotent vinblastines in which added molecular complexity further disrupts the target tubulin dimer-dimer interface. Proceedings of the National Academy of Sciences of the United States of America. PMID 27512044 DOI: 10.1073/Pnas.1611405113  0.465
2016 Allemann O, Brutsch M, Lukesh JC, Brody DM, Boger DL. Synthesis of a Potent Vinblastine: Rationally Designed Added Benign Complexity. Journal of the American Chemical Society. PMID 27356080 DOI: 10.1021/Jacs.6B04330  0.426
2014 Lukesh JC, Andersen KA, Wallin KK, Raines RT. Organocatalysts of oxidative protein folding inspired by protein disulfide isomerase. Organic & Biomolecular Chemistry. 12: 8598-602. PMID 25266373 DOI: 10.1039/C4Ob01738B  0.72
2014 Lukesh JC, Wallin KK, Raines RT. Pyrazine-derived disulfide-reducing agent for chemical biology. Chemical Communications (Cambridge, England). 50: 9591-4. PMID 25014913 DOI: 10.1039/C4Cc04491F  0.576
2013 Lukesh JC, Vanveller B, Raines RT. Thiols and selenols as electron-relay catalysts for disulfide-bond reduction. Angewandte Chemie (International Ed. in English). 52: 12901-4. PMID 24123634 DOI: 10.1002/Anie.201307481  0.742
2013 Lukesh JC, VanVeller B, Raines RT. Inside Cover: Thiols and Selenols as Electron-Relay Catalysts for Disulfide-Bond Reduction (Angew. Chem. Int. Ed. 49/2013) Angewandte Chemie International Edition. 52: 12748-12748. DOI: 10.1002/Anie.201309405  0.727
2013 Lukesh JC, VanVeller B, Raines RT. Innentitelbild: Thiols and Selenols as Electron-Relay Catalysts for Disulfide-Bond Reduction (Angew. Chem. 49/2013) Angewandte Chemie. 125: 12982-12982. DOI: 10.1002/Ange.201309405  0.729
2012 Lukesh JC, Palte MJ, Raines RT. A potent, versatile disulfide-reducing agent from aspartic acid. Journal of the American Chemical Society. 134: 4057-9. PMID 22353145 DOI: 10.1021/Ja211931F  0.739
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