Ulrich Arnold - Publications

Affiliations: 
2004-2007 University of Wisconsin, Madison, Madison, WI 

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Arnold U, Raines RT. Replacing a single atom accelerates the folding of a protein and increases its thermostability. Organic & Biomolecular Chemistry. PMID 27336677 DOI: 10.1039/C6Ob00980H  1
2015 Kiesgen S, Arndt MA, Körber C, Arnold U, Weber T, Halama N, Keller A, Bötticher B, Schlegelmilch A, Liebers N, Cremer M, Herold-Mende C, Dyckhoff G, Federspil PA, Jensen AD, et al. An EGF receptor targeting Ranpirnase-diabody fusion protein mediates potent antitumour activity in vitro and in vivo. Cancer Letters. 357: 364-73. PMID 25434798 DOI: 10.1016/J.Canlet.2014.11.054  1
2014 Kiesgen S, Liebers N, Cremer M, Arnold U, Weber T, Keller A, Herold-Mende C, Dyckhoff G, Jäger D, Kontermann RE, Arndt MA, Krauss J. A fusogenic dengue virus-derived peptide enhances antitumor efficacy of an antibody-ribonuclease fusion protein targeting the EGF receptor. Protein Engineering, Design & Selection : Peds. 27: 331-7. PMID 25301960 DOI: 10.1093/Protein/Gzu040  1
2014 Arnold U. Stability and folding of amphibian ribonuclease A superfamily members in comparison with mammalian homologues. The Febs Journal. 281: 3559-75. PMID 24966023 DOI: 10.1111/Febs.12891  1
2013 Hacke M, Gruber T, Schulenburg C, Balbach J, Arnold U. Consequences of proline-to-alanine substitutions for the stability and refolding of onconase. The Febs Journal. 280: 4454-62. PMID 23796075 DOI: 10.1111/Febs.12406  1
2013 Solé M, Brandt W, Arnold U. Striking stabilization of Rana catesbeiana ribonuclease 3 by guanidine hydrochloride. Febs Letters. 587: 737-42. PMID 23395613 DOI: 10.1016/J.Febslet.2013.01.056  1
2013 Arnold U, Huck BR, Gellman SH, Raines RT. Protein prosthesis: β-peptides as reverse-turn surrogates. Protein Science : a Publication of the Protein Society. 22: 274-9. PMID 23238807 DOI: 10.1002/Pro.2208  1
2012 Arnold U, Schöpfel M. Significant stabilization of ribonuclease A by additive effects. The Febs Journal. 279: 2508-19. PMID 22594773 DOI: 10.1111/J.1742-4658.2012.08632.X  1
2012 Arnold U. Stability and stabilization of proteins: The ribonuclease a example Proteomics Research Journal. 2: 273-308.  1
2011 Schöpfel M, Tziridis A, Arnold U, Stubbs MT. Towards a restriction proteinase: construction of a self-activating enzyme. Chembiochem : a European Journal of Chemical Biology. 12: 1523-7. PMID 21387509 DOI: 10.1002/Cbic.201000787  1
2011 Arnold U, Leich F, Neumann P, Lilie H, Ulbrich-Hofmann R. Crystal structure of RNase A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor. The Febs Journal. 278: 331-40. PMID 21134128 DOI: 10.1111/J.1742-4658.2010.07957.X  1
2011 Watkins RW, Arnold U, Raines RT. Ribonuclease S redux. Chemical Communications (Cambridge, England). 47: 973-5. PMID 21079871 DOI: 10.1039/C0Cc03864D  1
2011 Arnold U. Stability and stabilization of proteins: The Ribonucleasea example Proteomics Research Journal. 2: 85-120.  1
2010 Schulenburg C, Weininger U, Neumann P, Meiselbach H, Stubbs MT, Sticht H, Balbach J, Ulbrich-Hofmann R, Arnold U. Impact of the C-terminal disulfide bond on the folding and stability of onconase Chembiochem. 11: 978-986. PMID 20349493 DOI: 10.1002/Cbic.200900773  1
2009 Schulenburg C, Löw C, Weininger U, Mrestani-Klaus C, Hofmann H, Balbach J, Ulbrich-Hofmann R, Arnold U. The folding pathway of onconase is directed by a conserved intermediate Biochemistry. 48: 8449-8457. PMID 19655705 DOI: 10.1021/Bi900596J  1
2009 Arnold U. Incorporation of non-natural modules into proteins: structural features beyond the genetic code. Biotechnology Letters. 31: 1129-39. PMID 19404746 DOI: 10.1007/S10529-009-0002-9  1
2009 Pecher P, Arnold U. The effect of additional disulfide bonds on the stability and folding of ribonuclease A. Biophysical Chemistry. 141: 21-8. PMID 19155118 DOI: 10.1016/J.Bpc.2008.12.005  1
2009 Weininger U, Schulenburg C, Arnold U, Ulbrich-Hofmann R, Balbach J. Solution structure of onconase C87A/C104A Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Kb6/Pdb  0.4
2008 Arnold U. Aspects of the cytotoxic action of ribonucleases. Current Pharmaceutical Biotechnology. 9: 161-8. PMID 18673281 DOI: 10.2174/138920108784567263  1
2008 Arnold U. Therapeutic potential of RNases. Current Pharmaceutical Biotechnology. 9: 134. PMID 18673277 DOI: 10.2174/138920108784567290  1
2008 Arnold U. Editorial: The therapeutic potential of ribonucleases Current Pharmaceutical Biotechnology. 9: 134. DOI: 10.2174/138920108784567290  1
2007 Schulenburg C, Martinez-Senac MM, Löw C, Golbik R, Ulbrich-Hofmann R, Arnold U. Identification of three phases in Onconase refolding. The Febs Journal. 274: 5826-33. PMID 17944937 DOI: 10.1111/J.1742-4658.2007.06106.X  1
2007 Tam A, Arnold U, Soellner MB, Raines RT. Protein prosthesis: 1,5-disubstituted[1,2,3]triazoles as cis-peptide bond surrogates. Journal of the American Chemical Society. 129: 12670-1. PMID 17914828 DOI: 10.1021/Ja075865S  1
2007 Schulenburg C, Ardelt B, Ardelt W, Arnold U, Shogen K, Ulbrich-Hofmann R, Darzynkiewicz Z. The interdependence between catalytic activity, conformational stability, and cytotoxicity of onconase. Cancer Biology & Therapy. 6: 1233-9. PMID 17637563 DOI: 10.4161/Cbt.6.8.4423  1
2007 Leich F, Stöhr N, Rietz A, Ulbrich-Hofmann R, Arnold U. Endocytotic internalization as a crucial factor for the cytotoxicity of ribonucleases. The Journal of Biological Chemistry. 282: 27640-6. PMID 17635931 DOI: 10.1074/Jbc.M702240200  1
2006 Arnold U, Ulbrich-Hofmann R. Natural and engineered ribonucleases as potential cancer therapeutics. Biotechnology Letters. 28: 1615-22. PMID 16902846 DOI: 10.1007/S10529-006-9145-0  1
2006 Leich F, Köditz J, Ulbrich-Hofman R, Arnold U. Tandemization endows bovine pancreatic ribonuclease with cytotoxic activity. Journal of Molecular Biology. 358: 1305-13. PMID 16580680 DOI: 10.1016/J.Jmb.2006.03.007  1
2006 Arnold U, Schulenburg C, Schmidt D, Ulbrich-Hofmann R. Contribution of structural peculiarities of onconase to its high stability and folding kinetics. Biochemistry. 45: 3580-7. PMID 16533040 DOI: 10.1021/Bi0525223  1
2005 Arnold U, Köditz J, Markert Y, Ulbrich-Hofmann R. Local fluctuations vs. global unfolding of proteins investigated by limited proteolysis Biocatalysis and Biotransformation. 23: 159-167. DOI: 10.1080/10242420500183287  1
2004 Köditz J, Ulbrich-Hofmann R, Arnold U. Probing the unfolding region of ribonuclease A by site-directed mutagenesis. European Journal of Biochemistry / Febs. 271: 4147-56. PMID 15479244 DOI: 10.1111/J.1432-1033.2004.04355.X  1
2003 Markert Y, Köditz J, Ulbrich-Hofmann R, Arnold U. Proline versus charge concept for protein stabilization against proteolytic attack. Protein Engineering. 16: 1041-6. PMID 14983085 DOI: 10.1093/Protein/Gzg136  1
2003 Arnold U, Hinderaker MP, Köditz J, Golbik R, Ulbrich-Hofmann R, Raines RT. Protein prosthesis: a nonnatural residue accelerates folding and increases stability. Journal of the American Chemical Society. 125: 7500-1. PMID 12812474 DOI: 10.1021/Ja0351239  1
2002 Arnold U, Hinderaker MP, Raines RT. Semisynthesis of ribonuclease A using intein-mediated protein ligation. Thescientificworldjournal. 2: 1823-7. PMID 12806173 DOI: 10.1100/Tsw.2002.855  1
2002 Köditz J, Arnold U, Ulbrich-Hofmann R. Dissecting the effect of trifluoroethanol on ribonuclease A. Subtle structural changes detected by nonspecific proteases. European Journal of Biochemistry / Febs. 269: 3831-7. PMID 12153580 DOI: 10.1046/J.1432-1033.2002.03079.X  1
2002 Arnold U, Hinderaker MP, Nilsson BL, Huck BR, Gellman SH, Raines RT. Protein prosthesis: a semisynthetic enzyme with a beta-peptide reverse turn. Journal of the American Chemical Society. 124: 8522-3. PMID 12121081 DOI: 10.1021/Ja026114N  1
2001 Arnold U, Hinderaker MP, Raines RT. Semisynthesis of Protein variants Using Intein-Mediated Protein Ligation. Thescientificworldjournal. 1: 117. PMID 30147597 DOI: 10.1100/Tsw.2001.215  1
2001 Markert Y, Köditz J, Mansfeld J, Arnold U, Ulbrich-Hofmann R. Increased proteolytic resistance of ribonuclease A by protein engineering Protein Engineering. 14: 791-796. PMID 11739898 DOI: 10.1093/Protein/14.10.791  1
2001 Arnold U, Ulbrich-Hofmann R. Proteolytic degradation of ribonuclease A in the pretransition region of thermally and urea-induced unfolding European Journal of Biochemistry. 268: 93-97. PMID 11121107 DOI: 10.1046/J.1432-1327.2001.01849.X  1
2000 Arnold U, Ulbrich-Hofmann R. Differences in the denaturation behavior of ribonuclease A induced by temperature and guanidine hydrochloride Protein Journal. 19: 345-352. DOI: 10.1023/A:1026479212350  1
1999 Arnold U, Ulbrich-Hofmann R. Quantitative protein precipitation from guanidine hydrochloride- containing solutions by sodium deoxycholate/trichloroacetic acid Analytical Biochemistry. 271: 197-199. PMID 10419639 DOI: 10.1006/Abio.1999.4149  1
1999 Arnold U, Schierhorn A, Ulbrich-Hofmann R. Modification of the unfolding region in bovine pancreatic ribonuclease and its influence on the thermal stability and proteolytic fragmentation European Journal of Biochemistry. 259: 470-475. PMID 9914529 DOI: 10.1046/J.1432-1327.1999.00059.X  1
1999 Ulbrich-Hofmann R, Arnold U, Mansfeld J. The concept of the unfolding region for approaching the mechanisms of enzyme stabilization Journal of Molecular Catalysis - B Enzymatic. 7: 125-131. DOI: 10.1016/S1381-1177(99)00026-0  1
1998 Arnold U, Schierhorn A, Ulbrich-Hofmann R. Influence of the carbohydrate moiety on the proteolytic cleavage sites in ribonuclease B Journal of Protein Chemistry. 17: 397-405. PMID 9717736 DOI: 10.1023/A:1022562316513  1
1998 Arnold U, Ulbrich-Hofmann R. Modification of the carbohydrate moiety in ribonuclease B and its influence on the protein stability probed by limited proteolysis Progress in Biotechnology. 15: 121-126. DOI: 10.1016/S0921-0423(98)80020-8  1
1997 Arnold U, Ulbrich-Hofmann R. Kinetic and thermodynamic thermal stabilities of ribonuclease a and ribonuclease b Biochemistry. 36: 2166-2172. PMID 9047316 DOI: 10.1021/Bi962723U  1
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