Grant McClarty - Publications

Affiliations: 
University of Manitoba, Winnipeg, Manitoba, Canada 
Area:
Microbiology Biology

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Yang C, Kari L, Lei L, Carlson JH, Ma L, Couch CE, Whitmire WM, Bock K, Moore I, Bonner C, McClarty G, Caldwell HD. Chlamydia trachomatis Plasmid Gene Protein 3 Is Essential for the Establishment of Persistent Infection and Associated Immunopathology. Mbio. 11. PMID 32817110 DOI: 10.1128/Mbio.01902-20  0.31
2018 Patton MJ, Chen CY, Yang C, McCorrister S, Grant C, Westmacott G, Yuan XY, Ochoa E, Fariss R, Whitmire WM, Carlson JH, Caldwell HD, McClarty G. Plasmid Negative Regulation of CPAF Expression Is Pgp4 Independent and Restricted to Invasive Chlamydia trachomatis Biovars. Mbio. 9. PMID 29382731 DOI: 10.1128/Mbio.02164-17  0.409
2017 Yang C, Kari L, Sturdevant GL, Song L, Patton MJ, Couch CE, Ilgenfritz JM, Southern TR, Whitmire WM, Briones M, Bonner C, Grant C, Hu P, McClarty G, Caldwell HD. Chlamydia trachomatis ChxR is a transcriptional regulator of virulence factors that function in in vivo host pathogen interactions. Pathogens and Disease. PMID 28369275 DOI: 10.1093/Femspd/Ftx035  0.377
2016 Patton MJ, McCorrister S, Grant C, Westmacott G, Fariss R, Hu P, Zhao K, Blake M, Whitmire B, Yang C, Caldwell HD, McClarty G. Chlamydial Protease-Like Activity Factor and Type III Secreted Effectors Cooperate in Inhibition of p65 Nuclear Translocation. Mbio. 7. PMID 27677792 DOI: 10.1128/Mbio.01427-16  0.333
2014 Song L, Carlson JH, Zhou B, Virtaneva K, Whitmire WM, Sturdevant GL, Porcella SF, McClarty G, Caldwell HD. Plasmid-mediated transformation tropism of chlamydial biovars. Pathogens and Disease. 70: 189-93. PMID 24214488 DOI: 10.1111/2049-632X.12104  0.369
2013 Song L, Carlson JH, Whitmire WM, Kari L, Virtaneva K, Sturdevant DE, Watkins H, Zhou B, Sturdevant GL, Porcella SF, McClarty G, Caldwell HD. Chlamydia trachomatis plasmid-encoded pgp4 is a transcriptional regulator of virulence-associated genes Infection and Immunity. 81: 636-644. PMID 23319558 DOI: 10.1128/Iai.01305-12  0.36
2011 Kari L, Goheen MM, Randall LB, Taylor LD, Carlson JH, Whitmire WM, Virok D, Rajaram K, Endresz V, McClarty G, Nelson DE, Caldwell HD. Generation of targeted Chlamydia trachomatis null mutants. Proceedings of the National Academy of Sciences of the United States of America. 108: 7189-93. PMID 21482792 DOI: 10.1073/Pnas.1102229108  0.357
2010 Lutter EI, Bonner C, Holland MJ, Suchland RJ, Stamm WE, Jewett TJ, McClarty G, Hackstadt T. Phylogenetic analysis of Chlamydia trachomatis Tarp and correlation with clinical phenotype. Infection and Immunity. 78: 3678-88. PMID 20605986 DOI: 10.1128/Iai.00515-10  0.373
2008 Kari L, Whitmire WM, Carlson JH, Crane DD, Reveneau N, Nelson DE, Mabey DC, Bailey RL, Holland MJ, McClarty G, Caldwell HD. Pathogenic diversity among Chlamydia trachomatis ocular strains in nonhuman primates is affected by subtle genomic variations. The Journal of Infectious Diseases. 197: 449-56. PMID 18199030 DOI: 10.1086/525285  0.311
2007 Nelson DE, Taylor LD, Shannon JG, Whitmire WM, Crane DD, McClarty G, Su H, Kari L, Caldwell HD. Phenotypic rescue of Chlamydia trachomatis growth in IFN-gamma treated mouse cells by irradiated Chlamydia muridarum. Cellular Microbiology. 9: 2289-98. PMID 17501981 DOI: 10.1111/J.1462-5822.2007.00959.X  0.361
2007 McClarty G, Caldwell HD, Nelson DE. Chlamydial interferon gamma immune evasion influences infection tropism. Current Opinion in Microbiology. 10: 47-51. PMID 17208039 DOI: 10.1016/J.Mib.2006.12.003  0.357
2006 Carlson JH, Wood H, Roshick C, Caldwell HD, McClarty G. In vivo and in vitro studies of Chlamydia trachomatis TrpR:DNA interactions. Molecular Microbiology. 59: 1678-91. PMID 16553875 DOI: 10.1111/J.1365-2958.2006.05045.X  0.402
2006 Roshick C, Wood H, Caldwell HD, McClarty G. Comparison of gamma interferon-mediated antichlamydial defense mechanisms in human and mouse cells. Infection and Immunity. 74: 225-38. PMID 16368976 DOI: 10.1128/Iai.74.1.225-238.2006  0.32
2005 Carlson JH, Porcella SF, McClarty G, Caldwell HD. Comparative genomic analysis of Chlamydia trachomatis oculotropic and genitotropic strains. Infection and Immunity. 73: 6407-18. PMID 16177312 DOI: 10.1128/Iai.73.10.6407-6418.2005  0.359
2005 Nelson DE, Virok DP, Wood H, Roshick C, Johnson RM, Whitmire WM, Crane DD, Steele-Mortimer O, Kari L, McClarty G, Caldwell HD. Chlamydial IFN-gamma immune evasion is linked to host infection tropism. Proceedings of the National Academy of Sciences of the United States of America. 102: 10658-63. PMID 16020528 DOI: 10.1073/Pnas.0504198102  0.325
2005 Griffin J, Roshick C, Iliffe-Lee E, McClarty G. Catalytic mechanism of Chlamydia trachomatis flavin-dependent thymidylate synthase. The Journal of Biological Chemistry. 280: 5456-67. PMID 15591067 DOI: 10.1074/Jbc.M412415200  0.711
2004 Carlson JH, Hughes S, Hogan D, Cieplak G, Sturdevant DE, McClarty G, Caldwell HD, Belland RJ. Polymorphisms in the Chlamydia trachomatis cytotoxin locus associated with ocular and genital isolates. Infection and Immunity. 72: 7063-72. PMID 15557630 DOI: 10.1128/Iai.72.12.7063-7072.2004  0.368
2004 Högbom M, Stenmark P, Voevodskaya N, McClarty G, Gräslund A, Nordlund P. The radical site in chlamydial ribonucleotide reductase defines a new R2 subclass. Science (New York, N.Y.). 305: 245-8. PMID 15247479 DOI: 10.1126/Science.1098419  0.339
2004 Wood H, Roshick C, McClarty G. Tryptophan recycling is responsible for the interferon-gamma resistance of Chlamydia psittaci GPIC in indoleamine dioxygenase-expressing host cells. Molecular Microbiology. 52: 903-16. PMID 15101993 DOI: 10.1111/J.1365-2958.2004.04029.X  0.426
2004 Hatch GM, McClarty G. C. trachomatis-infection accelerates metabolism of phosphatidylcholine derived from low density lipoprotein but does not affect phosphatidylcholine secretion from hepatocytes. Bmc Microbiology. 4: 8. PMID 15018642 DOI: 10.1186/1471-2180-4-8  0.358
2004 Stenmark P, Högbom M, Roshick C, McClarty G, Nordlund P. Crystals of the ribonucleotide reductase R2 protein from Chlamydia trachomatis obtained by heavy-atom co-crystallization. Acta Crystallographica. Section D, Biological Crystallography. 60: 376-8. PMID 14747731 DOI: 10.1107/S0907444903028208  0.333
2004 Greene W, Xiao Y, Huang Y, McClarty G, Zhong G. Chlamydia-infected cells continue to undergo mitosis and resist induction of apoptosis. Infection and Immunity. 72: 451-60. PMID 14688126 DOI: 10.1128/Iai.72.1.451-460.2004  0.314
2004 Su H, McClarty G, Dong F, Hatch GM, Pan ZK, Zhong G. Activation of Raf/MEK/ERK/cPLA2 signaling pathway is essential for chlamydial acquisition of host glycerophospholipids. The Journal of Biological Chemistry. 279: 9409-16. PMID 14676189 DOI: 10.1074/Jbc.M312008200  0.37
2003 Wood H, Fehlner-Gardner C, Berry J, Fischer E, Graham B, Hackstadt T, Roshick C, McClarty G. Regulation of tryptophan synthase gene expression in Chlamydia trachomatis. Molecular Microbiology. 49: 1347-59. PMID 12940992 DOI: 10.1046/J.1365-2958.2003.03638.X  0.437
2003 Caldwell HD, Wood H, Crane D, Bailey R, Jones RB, Mabey D, Maclean I, Mohammed Z, Peeling R, Roshick C, Schachter J, Solomon AW, Stamm WE, Suchland RJ, Taylor L, ... ... McClarty G, et al. Polymorphisms in Chlamydia trachomatis tryptophan synthase genes differentiate between genital and ocular isolates. The Journal of Clinical Investigation. 111: 1757-69. PMID 12782678 DOI: 10.1172/Jci17993  0.409
2002 Fehlner-Gardiner C, Roshick C, Carlson JH, Hughes S, Belland RJ, Caldwell HD, McClarty G. Molecular basis defining human Chlamydia trachomatis tissue tropism. A possible role for tryptophan synthase. The Journal of Biological Chemistry. 277: 26893-903. PMID 12011099 DOI: 10.1074/Jbc.M203937200  0.313
2002 Iliffe-Lee ER, McClarty G. Pyruvate kinase from Chlamydia trachomatis is activated by fructose-2,6-bisphosphate. Molecular Microbiology. 44: 819-28. PMID 11994161 DOI: 10.1046/J.1365-2958.2002.02924.X  0.707
2001 Belland RJ, Scidmore MA, Crane DD, Hogan DM, Whitmire W, McClarty G, Caldwell HD. Chlamydia trachomatis cytotoxicity associated with complete and partial cytotoxin genes. Proceedings of the National Academy of Sciences of the United States of America. 98: 13984-9. PMID 11707582 DOI: 10.1073/Pnas.241377698  0.384
2000 Iliffe-Lee ER, McClarty G. Regulation of carbon metabolism in Chlamydia trachomatis. Molecular Microbiology. 38: 20-30. PMID 11029687 DOI: 10.1046/J.1365-2958.2000.02102.X  0.699
2000 Roshick C, Iliffe-Lee ER, McClarty G. Cloning and characterization of ribonucleotide reductase from Chlamydia trachomatis. The Journal of Biological Chemistry. 275: 38111-9. PMID 10984489 DOI: 10.1074/Jbc.M006367200  0.704
1999 Iliffe-Lee ER, McClarty G. Glucose metabolism in Chlamydia trachomatis: the 'energy parasite' hypothesis revisited. Molecular Microbiology. 33: 177-87. PMID 10411734 DOI: 10.1046/J.1365-2958.1999.01464.X  0.732
1998 Hatch GM, Mcclarty G. Phospholipid composition of purified Chlamydia trachomatis mimics that of the eucaryotic host cell Infection and Immunity. 66: 3727-3735. PMID 9673255 DOI: 10.1128/Iai.66.8.3727-3735.1998  0.372
1998 Hatch GM, McClarty G. Cardiolipin remodeling in eukaryotic cells infected with Chlamydia trachomatis is linked to elevated mitochondrial metabolism Biochemical and Biophysical Research Communications. 243: 356-360. PMID 9480813 DOI: 10.1006/Bbrc.1998.8101  0.354
1997 Wylie JL, Hatch GM, Mcclarty G. Host cell phospholipids are trafficked to and then modified by Chlamydia trachomatis Journal of Bacteriology. 179: 7233-7242. PMID 9393685 DOI: 10.1128/Jb.179.23.7233-7242.1997  0.365
1997 Rusnak A, Mangat R, Xu F, McClarty G, Hatch GM. Cardiolipin remodeling in a Chinese hamster lung fibroblast cell line deficient in oxidative energy production Journal of Bioenergetics and Biomembranes. 29: 291-298. PMID 9298714 DOI: 10.1023/A:1022418328922  0.301
1997 Wylie JL, Iliffe ER, Ling Ling Wang, McClarty G. Identification, characterization, and developmental regulation of Chlamydia trachomatis 3-deoxy-D-manno-octulosonate (KDO)-8-phosphate synthetase and CMP-KDO synthetase Infection and Immunity. 65: 1527-1530. PMID 9119498 DOI: 10.1128/Iai.65.4.1527-1530.1997  0.441
1996 Wylie JL, Berry JD, McClarty G. Chlamydia trachomatis CTP synthetase: Molecular characterization and developmental regulation of expression Molecular Microbiology. 22: 631-642. PMID 8951811 DOI: 10.1046/J.1365-2958.1996.D01-1717.X  0.503
1996 Hatch GM, McClarty G. Regulation of cardiolipin biosynthesis in H9c2 cardiac myoblasts by cytidine 5'-triphosphate Journal of Biological Chemistry. 271: 25810-25816. PMID 8824210 DOI: 10.1074/Jbc.271.42.25810  0.394
1996 Wylie JL, Wang LL, Tipples G, McClarty G. A single point mutation in CTP synthetase of Chlamydia trachomatis confers resistance to cyclopentenyl cytosine Journal of Biological Chemistry. 271: 15393-15400. PMID 8663065 DOI: 10.1074/Jbc.271.26.15393  0.39
1995 Tipples G, McClarty G. Cloning and expression of the Chlamydia trachomatis gene for CTP synthetase Journal of Biological Chemistry. 270: 7908-7914. PMID 7713886 DOI: 10.1074/Jbc.270.14.7908  0.404
1994 McClarty G. Chlamydiae and the biochemistry of intracellular parasitism Trends in Microbiology. 2: 157-164. PMID 8055179 DOI: 10.1016/0966-842X(94)90665-3  0.331
1994 Wang LL, Henson E, McClarty G. Characterization of trimethoprim- and sulphisoxazole-resistant Chlamydia trachomatis Molecular Microbiology. 14: 271-281. PMID 7530318 DOI: 10.1111/J.1365-2958.1994.Tb01288.X  0.321
1993 McClarty G, Fan H, Andersen AA. Diversity in nucleotide acquisition by antigenically similar Chlamydia psittaci of avian origin Fems Microbiology Letters. 108: 325-331. PMID 8514120 DOI: 10.1111/J.1574-6968.1993.Tb06123.X  0.358
1993 Tipples G, McClarty G. The obligate intracellular bacterium Clamydia trachomatis is auxotrophic for three of the four ribonucleoside triphosphates Molecular Microbiology. 8: 1105-1114. PMID 8361355 DOI: 10.1111/J.1365-2958.1993.Tb01655.X  0.439
1993 McClarty G, Fan H. Purine metabolism by intracellular Chlamydia psittaci Journal of Bacteriology. 175: 4662-4669. PMID 8335625 DOI: 10.1128/Jb.175.15.4662-4669.1993  0.451
1993 McClarty G, Qin B. Pyrimidine metabolism by intracellular Chlamydia psittaci Journal of Bacteriology. 175: 4652-4661. PMID 8335624  0.33
1992 Qin B, McClarty G. Effect of 6-thioguanine on Chlamydia trachomatis growth in wild-type and hypoxanthine-guanine phosphoribosyltransferase-deficient cells Journal of Bacteriology. 174: 2865-2873. PMID 1569017 DOI: 10.1128/Jb.174.9.2865-2873.1992  0.392
1992 Fan H, Brunham RC, McClarty G. Acquisition and synthesis of folates by obligate intracellular bacteria of the genus Chlamydia Journal of Clinical Investigation. 90: 1803-1811. PMID 1430206 DOI: 10.1172/Jci116055  0.374
1991 Fan H, McClarty G, Brunham RC. Biochemical evidence for the existence of thymidylate synthase in the obligate intracellular parasite Chlamydia trachomatis Journal of Bacteriology. 173: 6670-6677. PMID 1938873 DOI: 10.1128/Jb.173.21.6670-6677.1991  0.432
1991 McClarty G, Tipples G. In situ studies on incorporation of nucleic acid precursors into Chlamydia trachomatis DNA Journal of Bacteriology. 173: 4922-4931. PMID 1907263 DOI: 10.1128/Jb.173.16.4922-4931.1991  0.376
1991 Tipples G, McClarty G. Isolation and initial characterization of a series of Chlamydia trachomatis isolates selected for hydroxyurea resistance by a stepwise procedure Journal of Bacteriology. 173: 4932-4940. PMID 1860812 DOI: 10.1128/Jb.173.16.4932-4940.1991  0.454
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